BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0203.p (455 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2720 [F] COG0015 Adenylosuccinate lyase Rso Ralstonia solanac... 749 0.0 PA2629 [F] COG0015 Adenylosuccinate lyase Pae Pseudomonas aerugi... 665 0.0 VC1126 [F] COG0015 Adenylosuccinate lyase Vch Vibrio cholerae 644 0.0 NMA2203 [F] COG0015 Adenylosuccinate lyase NmA Neisseria meningi... 631 e-180 NMB0284 [F] COG0015 Adenylosuccinate lyase Nme Neisseria meningi... 630 e-180 HI0639 [F] COG0015 Adenylosuccinate lyase Hin Haemophilus influe... 630 e-180 ZpurB [F] COG0015 Adenylosuccinate lyase EcZ Escherichia coli O1... 624 e-178 ECs1603 [F] COG0015 Adenylosuccinate lyase Ecs Escherichia coli ... 624 e-178 purB [F] COG0015 Adenylosuccinate lyase Eco Escherichia coli K12 624 e-178 STM1232 [F] COG0015 Adenylosuccinate lyase Sty Salmonella typhim... 614 e-175 >RSc2720 [F] COG0015 Adenylosuccinate lyase Rso Ralstonia solanacearum Length = 457 Score = 749 bits (1933), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/454 (79%), Positives = 395/454 (87%) Query: 2 SLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALSEAGFAEIKPFSAT 61 SLSAL+ALSP+DGRYA+K D LR LSEA FM HRVKVE+ WL ALS+AG AEI FSA Sbjct: 3 SLSALTALSPIDGRYAAKADPLREWLSEAAFMRHRVKVEVHWLIALSQAGLAEIPRFSAD 62 Query: 62 ALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFACT 121 A L L F EADAARIKEIEAVTNHDVKAVEYWLKE+VK EL AASEFIHFACT Sbjct: 63 AERALLALVDHFAEADAARIKEIEAVTNHDVKAVEYWLKERVKGNAELEAASEFIHFACT 122 Query: 122 SEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTLGK 181 SEDINNTSHGMMLK ARDTV++P+L+ V +L ELAH +A VPMLSRTHGQPASPTTLGK Sbjct: 123 SEDINNTSHGMMLKGARDTVIVPTLRRVQARLVELAHANADVPMLSRTHGQPASPTTLGK 182 Query: 182 EVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGLVF 241 E+ANV ARL RA +RI AVE+LGKMNGAVGNYNAHLSAYP DW AFSK V+E RLGL F Sbjct: 183 EMANVAARLDRAIRRIEAVELLGKMNGAVGNYNAHLSAYPDADWEAFSKSVIETRLGLTF 242 Query: 242 NPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMPHK 301 NPYTIQIEPHDYMAELFDAVAR NTI+LDL+RD+WGYIS GYFKQ+TKAGEIGSSTMPHK Sbjct: 243 NPYTIQIEPHDYMAELFDAVARANTIILDLDRDVWGYISQGYFKQKTKAGEIGSSTMPHK 302 Query: 302 VNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDSCL 361 VNPIDFENSEGN+G+ANAVL+HL+EKLPVSRWQRDLTDSTVLRNIGV FGY+LLAYD+CL Sbjct: 303 VNPIDFENSEGNVGLANAVLRHLSEKLPVSRWQRDLTDSTVLRNIGVAFGYSLLAYDACL 362 Query: 362 RGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDALRD 421 RGL KLE NP RLA+DLDA WEVLAEPVQTVMRRYGI NPYEQLKELTRGKGIS++ALR+ Sbjct: 363 RGLGKLETNPARLAEDLDACWEVLAEPVQTVMRRYGIANPYEQLKELTRGKGISREALRE 422 Query: 422 FINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 FI LAIP+ A+ LL MTP +Y+G A ELA++I Sbjct: 423 FIGTLAIPEAARQQLLDMTPGSYVGKAVELARRI 456 >PA2629 [F] COG0015 Adenylosuccinate lyase Pae Pseudomonas aeruginosa Length = 456 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 314/456 (68%), Positives = 374/456 (82%), Gaps = 1/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFS 59 M LS+L+A+SP+DGRYA KT LRP+ SE G + RV VE+ WLQ L+ AG E+ PFS Sbjct: 1 MQLSSLTAVSPVDGRYAGKTSSLRPIFSEYGLIRFRVMVEVRWLQRLAAHAGIPEVAPFS 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A ALLD LA+DF A RIKEIE TNHDVKAVEY LKE+ +PEL A SEFIHFA Sbjct: 61 AEANALLDSLASDFQLEHAERIKEIERTTNHDVKAVEYLLKEQAAKLPELAAVSEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINN SH +ML+ RD+VLLP ++ + + ELA + A VPMLSRTHGQPASPTTL Sbjct: 121 CTSEDINNLSHALMLREGRDSVLLPLMRQIAEAIRELAVKLADVPMLSRTHGQPASPTTL 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANVV RL+R K++A +E+LGK+NGAVGNYNAHLSAYP+ DW A ++Q +E LGL Sbjct: 181 GKELANVVYRLERQIKQVAGIELLGKINGAVGNYNAHLSAYPEVDWEANARQFIEGDLGL 240 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 FNPYT QIEPHDY+AELFDA+AR NTIL+D +RD+WGYISLGYFKQ+T AGEIGSSTMP Sbjct: 241 TFNPYTTQIEPHDYIAELFDAIARFNTILIDFDRDVWGYISLGYFKQKTVAGEIGSSTMP 300 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG+ANA+ +HLA KLP+SRWQRDLTDSTVLRN+GVG ++++AY++ Sbjct: 301 HKVNPIDFENSEGNLGIANALFQHLASKLPISRWQRDLTDSTVLRNLGVGIAHSIIAYEA 360 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 L+G+ KLE+N QR+A+DLDA WEVLAEPVQTVMRRYG+ENPYE+LKELTRGKGIS +AL Sbjct: 361 SLKGIGKLELNAQRIAEDLDACWEVLAEPVQTVMRRYGVENPYEKLKELTRGKGISAEAL 420 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 + FI LAIP EAK L +TPA Y+G AA AK+I Sbjct: 421 QTFIEELAIPAEAKVELKKLTPAGYVGNAAAQAKRI 456 >VC1126 [F] COG0015 Adenylosuccinate lyase Vch Vibrio cholerae Length = 456 Score = 644 bits (1662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 307/456 (67%), Positives = 369/456 (80%), Gaps = 1/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFS 59 M LSAL+A+SP+DGRY SKT LR + SE G + +R VEI WLQ L+ A AE+ FS Sbjct: 1 MELSALTAVSPVDGRYGSKTIALRSIFSEFGLLKYRTIVEIRWLQKLAATAEIAEVPAFS 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A LD +AA+F EADA RIKEIE TNHDVKAVEY+LKEKV +PEL A +EFIHFA Sbjct: 61 AEANQFLDAIAANFNEADALRIKEIERTTNHDVKAVEYFLKEKVAAMPELHAVNEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINNTSH +MLK ARDTV+LP ++ VI + +LA E+ +P+LSRTHGQPASP+T+ Sbjct: 121 CTSEDINNTSHALMLKEARDTVILPEIRNVIDAIRKLAEEYRDIPLLSRTHGQPASPSTM 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANV R++R K+IA VEIL K+NGAVGNYNAHLSAYP DW FS++ + + LG+ Sbjct: 181 GKEMANVAYRMERQYKQIANVEILAKINGAVGNYNAHLSAYPTVDWHKFSEEFITESLGV 240 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 +NPYT QIEPHDY+AELF+AVAR NTIL+D +RD+WGYI+LG+FKQRT AGEIGSSTMP Sbjct: 241 DWNPYTTQIEPHDYIAELFEAVARFNTILIDFDRDVWGYIALGHFKQRTIAGEIGSSTMP 300 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG+ANAV HLA+KLP+SRWQRDLTDSTVLRN+GVG GY ++AY S Sbjct: 301 HKVNPIDFENSEGNLGLANAVFTHLAQKLPISRWQRDLTDSTVLRNLGVGVGYAIIAYTS 360 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 L+G++KLEVN L +LD WEVLAEP+QTVMRRYGIE PYE+LKELTRGK + +A+ Sbjct: 361 TLKGISKLEVNRDALLAELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDGEAM 420 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 R FI+GLA+P E K L AMTPA+YIG A EL ++ Sbjct: 421 RQFIDGLALPAEEKTRLKAMTPASYIGYAIELTDKL 456 >NMA2203 [F] COG0015 Adenylosuccinate lyase NmA Neisseria meningitidis Z2491 Length = 456 Score = 631 bits (1627), Expect = e-180, Method: Compositional matrix adjust. Identities = 306/455 (67%), Positives = 361/455 (79%), Gaps = 2/455 (0%) Query: 3 LSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFSAT 61 ++ +++LSPLDGRYA + LRP+ SE G M RVKVE+ WL+AL+ E AE+ PFSA Sbjct: 2 INPIASLSPLDGRYAQSVEALRPIFSEYGLMKARVKVELNWLKALAAEPKIAEVPPFSAE 61 Query: 62 ALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFACT 121 LA +D + +F+ DAA +K IEA TNHDVKA+EYWLK++ +VPE+ A SEFIHFACT Sbjct: 62 TLAEIDTVIENFSLEDAAAVKAIEATTNHDVKAIEYWLKKRFAEVPEVAAVSEFIHFACT 121 Query: 122 SEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTLGK 181 SEDINN SH +ML+ AR+ VLLP L +I KLT +AH+ AAVPM+SRTHGQPA+PTTLGK Sbjct: 122 SEDINNLSHALMLQEAREAVLLPKLAEIIEKLTAMAHDLAAVPMMSRTHGQPATPTTLGK 181 Query: 182 EVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGLVF 241 E ANVV RLQR K + A E LGK+NGAVGNYNAH+ AYP DW + VE LGL F Sbjct: 182 ETANVVYRLQRQFKSLQAQEFLGKINGAVGNYNAHMVAYPDVDWETHCRNFVEISLGLTF 241 Query: 242 NPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMPHK 301 NPYTIQIEPHDYMAE F ++R NTIL+D NRD+WGYISLGYFKQ+ KAGE+GSSTMPHK Sbjct: 242 NPYTIQIEPHDYMAEFFQTLSRINTILIDFNRDVWGYISLGYFKQKVKAGEVGSSTMPHK 301 Query: 302 VNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDSCL 361 VNPIDFENSEGNLGMANAVL LAEKLP+SRWQRDLTDSTVLRN+GVG GY +L + + L Sbjct: 302 VNPIDFENSEGNLGMANAVLGFLAEKLPISRWQRDLTDSTVLRNMGVGVGYAVLGFAAHL 361 Query: 362 RGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGK-GISKDALR 420 RGLNKLE NP LA DLDATWE+LAEP+QTVMRRYG+ NPYE+LK+LTRGK GI+ + L+ Sbjct: 362 RGLNKLEPNPAALAADLDATWELLAEPIQTVMRRYGVANPYEKLKDLTRGKGGITPEVLK 421 Query: 421 DFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 FI L IP EAK LL +TPA Y+G A LAK+I Sbjct: 422 GFIGLLEIPAEAKAKLLELTPALYVGKAEALAKRI 456 >NMB0284 [F] COG0015 Adenylosuccinate lyase Nme Neisseria meningitidis MC58 Length = 456 Score = 630 bits (1624), Expect = e-180, Method: Compositional matrix adjust. Identities = 305/455 (67%), Positives = 361/455 (79%), Gaps = 2/455 (0%) Query: 3 LSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFSAT 61 ++ +++LSPLDGRYA + LRP+ SE G M RVKVE+ WL+AL+ E AE+ PFSA Sbjct: 2 INPIASLSPLDGRYAQSVEALRPIFSEYGLMKARVKVELNWLKALAAEPKIAEVPPFSAE 61 Query: 62 ALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFACT 121 LA +D + +F+ DAA +K IEA TNHDVKA+EYWLK++ +VPE+ A SEFIHFACT Sbjct: 62 TLAEIDTVIENFSLEDAAAVKAIEATTNHDVKAIEYWLKKRFAEVPEVAAVSEFIHFACT 121 Query: 122 SEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTLGK 181 SEDINN SH +ML+ AR+ VLLP L +I KLT +AH+ AAVPM+SRTHGQPA+PTTLGK Sbjct: 122 SEDINNLSHALMLQEAREAVLLPKLAEIIEKLTAMAHDLAAVPMMSRTHGQPATPTTLGK 181 Query: 182 EVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGLVF 241 E ANVV RLQR K + A E LGK+NGAVGNYNAH+ AYP DW + VE LGL F Sbjct: 182 ETANVVYRLQRQFKNLQAQEFLGKINGAVGNYNAHMVAYPDVDWETHCRNFVEISLGLTF 241 Query: 242 NPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMPHK 301 NPYTIQIEPHDYMAE F ++R NTIL+D NRD+WGYISLGYFKQ+ KAGE+GSSTMPHK Sbjct: 242 NPYTIQIEPHDYMAEFFQTLSRINTILIDFNRDVWGYISLGYFKQKVKAGEVGSSTMPHK 301 Query: 302 VNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDSCL 361 VNPIDFENSEGNLGMANAVL L+EKLP+SRWQRDLTDSTVLRN+GVG GY +L + + L Sbjct: 302 VNPIDFENSEGNLGMANAVLGFLSEKLPISRWQRDLTDSTVLRNMGVGVGYAVLGFAAHL 361 Query: 362 RGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGK-GISKDALR 420 RGLNKLE NP LA DLDATWE+LAEP+QTVMRRYG+ NPYE+LK+LTRGK GI+ + L+ Sbjct: 362 RGLNKLEPNPAALAADLDATWELLAEPIQTVMRRYGVANPYEKLKDLTRGKGGITPEVLK 421 Query: 421 DFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 FI L IP EAK LL +TPA Y+G A LAK+I Sbjct: 422 GFIGLLEIPAEAKAKLLELTPALYVGKAEALAKRI 456 >HI0639 [F] COG0015 Adenylosuccinate lyase Hin Haemophilus influenzae Length = 456 Score = 630 bits (1624), Expect = e-180, Method: Compositional matrix adjust. Identities = 298/456 (65%), Positives = 358/456 (78%), Gaps = 2/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQAL-SEAGFAEIKPFS 59 M LS L+ALSPLDGRY K LR + SE G M RV VE+ WLQ L S A E+ PFS Sbjct: 1 MQLSTLTALSPLDGRYQDKVTPLRAIFSEFGLMKFRVAVEVRWLQKLASTADITEVPPFS 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A LD + A+F EADAARIKEIE TNHDVKAVEY+LKEK+++ ELV SEFIHFA Sbjct: 61 TQANAFLDGIVANFNEADAARIKEIERTTNHDVKAVEYFLKEKIQNEVELVKVSEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINN SH +ML ARD V+LP Q +I ++T LA E+ +P+LSRTHGQPASP+T+ Sbjct: 121 CTSEDINNLSHALMLSTARDEVILPEWQKLIDEITRLAEEYKTIPLLSRTHGQPASPSTV 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANVV RL+R K++ EILGK+NGAVGNYNAHLSAYP DW FS++ V LG+ Sbjct: 181 GKEMANVVYRLKRQFKQLQNAEILGKINGAVGNYNAHLSAYPNIDWHKFSEEFVTS-LGI 239 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 +NPYT QIEPHDY+ E FDAV R NTI++D +RD+WGYI+L +FKQRT AGEIGSSTMP Sbjct: 240 QWNPYTTQIEPHDYITEFFDAVVRFNTIIIDFDRDLWGYIALNHFKQRTIAGEIGSSTMP 299 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG+ANAV+ HL +KLP+SRWQRDLTDSTVLRN+GVG GY L+AY S Sbjct: 300 HKVNPIDFENSEGNLGLANAVMTHLGQKLPISRWQRDLTDSTVLRNLGVGLGYCLIAYAS 359 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 +G++KLEVN L ++L+ WEVLAEP+QTVMRRYGIE PYE+LKELTRGK +++ A+ Sbjct: 360 TRKGISKLEVNQPHLLEELNQNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVTEQAM 419 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 R+FI+ L IPQE K L +TPA YIG A EL +++ Sbjct: 420 REFIDKLDIPQEEKLRLQKLTPATYIGAAVELVEKL 455 >ZpurB [F] COG0015 Adenylosuccinate lyase EcZ Escherichia coli O157:H7 EDL933 Length = 456 Score = 624 bits (1609), Expect = e-178, Method: Compositional matrix adjust. Identities = 291/456 (63%), Positives = 364/456 (79%), Gaps = 2/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFS 59 M LS+L+A+SP+DGRY K LR + SE G + RV+VE+ WLQ L+ A E+ F+ Sbjct: 1 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFA 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A+ LD + A+F+E DAARIK IE TNHDVKAVEY+LKEKV ++PEL A SEFIHFA Sbjct: 61 ADAIGYLDAIVANFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINN SH +MLK ARD V+LP + +I + +LA ++ +P+LSRTHGQPA+P+T+ Sbjct: 121 CTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTI 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANV R++R +++ VEILGK+NGAVGNYNAH++AYP+ DW FS++ V LG+ Sbjct: 181 GKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTS-LGI 239 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 +NPYT QIEPHDY+AELFD VAR NTIL+D +RD+WGYI+L +FKQ+T AGEIGSSTMP Sbjct: 240 QWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMP 299 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG++NAVL+HLA KLPVSRWQRDLTDSTVLRN+GVG GY L+AY S Sbjct: 300 HKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQS 359 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 L+G++KLEVN L D+LD WEVLAEP+QTVMRRYGIE PYE+LKELTRGK + + + Sbjct: 360 TLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGM 419 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 + FI+GLA+P+E K L AMTPANYIG A + ++ Sbjct: 420 KQFIDGLALPEEEKARLKAMTPANYIGRAITMVDEL 455 >ECs1603 [F] COG0015 Adenylosuccinate lyase Ecs Escherichia coli O157:H7 Length = 456 Score = 624 bits (1609), Expect = e-178, Method: Compositional matrix adjust. Identities = 291/456 (63%), Positives = 364/456 (79%), Gaps = 2/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFS 59 M LS+L+A+SP+DGRY K LR + SE G + RV+VE+ WLQ L+ A E+ F+ Sbjct: 1 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFA 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A+ LD + A+F+E DAARIK IE TNHDVKAVEY+LKEKV ++PEL A SEFIHFA Sbjct: 61 ADAIGYLDAIVANFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINN SH +MLK ARD V+LP + +I + +LA ++ +P+LSRTHGQPA+P+T+ Sbjct: 121 CTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTI 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANV R++R +++ VEILGK+NGAVGNYNAH++AYP+ DW FS++ V LG+ Sbjct: 181 GKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTS-LGI 239 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 +NPYT QIEPHDY+AELFD VAR NTIL+D +RD+WGYI+L +FKQ+T AGEIGSSTMP Sbjct: 240 QWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMP 299 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG++NAVL+HLA KLPVSRWQRDLTDSTVLRN+GVG GY L+AY S Sbjct: 300 HKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQS 359 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 L+G++KLEVN L D+LD WEVLAEP+QTVMRRYGIE PYE+LKELTRGK + + + Sbjct: 360 TLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGM 419 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 + FI+GLA+P+E K L AMTPANYIG A + ++ Sbjct: 420 KQFIDGLALPEEEKARLKAMTPANYIGRAITMVDEL 455 >purB [F] COG0015 Adenylosuccinate lyase Eco Escherichia coli K12 Length = 456 Score = 624 bits (1608), Expect = e-178, Method: Compositional matrix adjust. Identities = 291/456 (63%), Positives = 363/456 (79%), Gaps = 2/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFS 59 M LS+L+A+SP+DGRY K LR + SE G + RV+VE+ WLQ L+ A E+ F+ Sbjct: 1 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFA 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A+ LD + A F+E DAARIK IE TNHDVKAVEY+LKEKV ++PEL A SEFIHFA Sbjct: 61 ADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINN SH +MLK ARD V+LP + +I + +LA ++ +P+LSRTHGQPA+P+T+ Sbjct: 121 CTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQYRDIPLLSRTHGQPATPSTI 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANV R++R +++ VEILGK+NGAVGNYNAH++AYP+ DW FS++ V LG+ Sbjct: 181 GKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTS-LGI 239 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 +NPYT QIEPHDY+AELFD VAR NTIL+D +RD+WGYI+L +FKQ+T AGEIGSSTMP Sbjct: 240 QWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMP 299 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG++NAVL+HLA KLPVSRWQRDLTDSTVLRN+GVG GY L+AY S Sbjct: 300 HKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQS 359 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 L+G++KLEVN L D+LD WEVLAEP+QTVMRRYGIE PYE+LKELTRGK + + + Sbjct: 360 TLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGM 419 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 + FI+GLA+P+E K L AMTPANYIG A + ++ Sbjct: 420 KQFIDGLALPEEEKARLKAMTPANYIGRAITMVDEL 455 >STM1232 [F] COG0015 Adenylosuccinate lyase Sty Salmonella typhimurium LT2 Length = 456 Score = 614 bits (1584), Expect = e-175, Method: Compositional matrix adjust. Identities = 290/456 (63%), Positives = 356/456 (78%), Gaps = 2/456 (0%) Query: 1 MSLSALSALSPLDGRYASKTDKLRPLLSEAGFMHHRVKVEIAWLQALS-EAGFAEIKPFS 59 M LS+L+A+SP+DGRY K LR + SE G + RV+VE+ WLQ L+ A E+ F+ Sbjct: 1 MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFA 60 Query: 60 ATALALLDKLAADFTEADAARIKEIEAVTNHDVKAVEYWLKEKVKDVPELVAASEFIHFA 119 A A LD L A+F E DAARIK IE TNHDVKAVEY+LKEKV +P L SEFIHFA Sbjct: 61 ADANGYLDTLVANFNEEDAARIKTIERTTNHDVKAVEYFLKEKVAAIPALHDVSEFIHFA 120 Query: 120 CTSEDINNTSHGMMLKAARDTVLLPSLQAVITKLTELAHEHAAVPMLSRTHGQPASPTTL 179 CTSEDINN SH +MLK ARD V+LP + VI + +LA ++ +P+LSRTHGQPA+P+TL Sbjct: 121 CTSEDINNLSHALMLKTARDEVILPYWRQVINAVKDLATQYRDIPLLSRTHGQPATPSTL 180 Query: 180 GKEVANVVARLQRAAKRIAAVEILGKMNGAVGNYNAHLSAYPQTDWAAFSKQVVEQRLGL 239 GKE+ANV R++R +++ VEILGK+NGAVGNYNAH++AYP+ DW FS++ V LG+ Sbjct: 181 GKEMANVAYRMERQFRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTS-LGI 239 Query: 240 VFNPYTIQIEPHDYMAELFDAVARTNTILLDLNRDIWGYISLGYFKQRTKAGEIGSSTMP 299 +NPYT QIEPHDY+AELFD +AR NTIL+D +RD+WGYI+L +FKQ+T AGEIGSSTMP Sbjct: 240 QWNPYTTQIEPHDYIAELFDCIARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMP 299 Query: 300 HKVNPIDFENSEGNLGMANAVLKHLAEKLPVSRWQRDLTDSTVLRNIGVGFGYTLLAYDS 359 HKVNPIDFENSEGNLG++NAVL HLA KLPVSRWQRDLTDSTVLRN+GVG GY L+AY S Sbjct: 300 HKVNPIDFENSEGNLGLSNAVLHHLANKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQS 359 Query: 360 CLRGLNKLEVNPQRLADDLDATWEVLAEPVQTVMRRYGIENPYEQLKELTRGKGISKDAL 419 L+G++KLEVN L D+LD WEVLAEP+QTVMRRYGIE PYE+LKELTRGK + + + Sbjct: 360 TLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEKPYEKLKELTRGKRVDAEGM 419 Query: 420 RDFINGLAIPQEAKDHLLAMTPANYIGTAAELAKQI 455 + FI+ LA+P+ K L AMTPANYIG A L ++ Sbjct: 420 KQFIDSLALPEAEKTRLKAMTPANYIGRAVTLVDEL 455