BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0161.p (311 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4926 [E] COG1305 Transglutaminase-like enzymes, putative cyste... 311 2e-84 ML0508 [E] COG1305 Transglutaminase-like enzymes, putative cyste... 196 6e-50 Rv2569c [E] COG1305 Transglutaminase-like enzymes, putative cyst... 196 7e-50 MT2645 [E] COG1305 Transglutaminase-like enzymes, putative cyste... 196 7e-50 mll2875 [E] COG1305 Transglutaminase-like enzymes, putative cyst... 177 4e-44 AGl1957 [E] COG1305 Transglutaminase-like enzymes, putative cyst... 171 2e-42 SMc04058 [E] COG1305 Transglutaminase-like enzymes, putative cys... 158 1e-38 CC1600 Non COG 144 2e-34 SMb20888 [E] COG1305 Transglutaminase-like enzymes, putative cys... 143 6e-34 DR1993 [E] COG1305 Transglutaminase-like enzymes, putative cyste... 134 4e-31 >PA4926 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Pae Pseudomonas aeruginosa Length = 311 Score = 311 bits (796), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 159/302 (52%), Positives = 194/302 (64%), Gaps = 8/302 (2%) Query: 7 YRIHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDNFGNIIK 66 Y++ H T Y+YA+PV LS Q+ HL PRE WQAC + I P P D FGN + Sbjct: 16 YQVLHDTHYRYAMPVSLSRQLAHLWPRECAWQACHERALLIEPGPSRREDGHDAFGNPLS 75 Query: 67 AFSLDTDHTSLDVQADSWVALSARGQPQ--AQMAWDEAAMQMAYHGGRVMTPGMLEASNF 124 + + H +L V A V + A Q A AW+ A +A+ GR ++ LEA + Sbjct: 76 RLAFERPHEALRVSARLQVEVFAHAPAQLTASPAWETVAAGLAF-SGRALSAAELEACRY 134 Query: 125 LFESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVTEVFV 184 ES +VRI+R F +AA+CF PG +L LM +I EFAFD AT V+TP+ EV Sbjct: 135 RVESPYVRIQRRFAEFAADCFPPGRPLLVAAAALMEKIFREFAFDAQATQVATPLDEVLE 194 Query: 185 NRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYCPGVN 244 RRGVCQDFAHLML+CLR+ GLAARYVSGYLLT PPPGQ RLIGADASHAWVS+YCP Sbjct: 195 RRRGVCQDFAHLMLACLRARGLAARYVSGYLLTRPPPGQARLIGADASHAWVSLYCP--- 251 Query: 245 GAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQSMQVAVTVLPAEEA 304 E W+D DPTN + PD HITL WGRDF D+SPLRGV++GGG +V VTVLP +E Sbjct: 252 --ENGWVDFDPTNDLLPDLEHITLAWGRDFSDVSPLRGVILGGGSHDPEVRVTVLPLQET 309 Query: 305 QG 306 G Sbjct: 310 AG 311 >ML0508 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Mle Mycobacterium leprae Length = 313 Score = 196 bits (498), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 110/297 (37%), Positives = 164/297 (55%), Gaps = 6/297 (2%) Query: 7 YRIHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDNFGNIIK 66 YR+ H+T Y+Y+ V S+ LTP + Q C+ H ++I P P D++GNI Sbjct: 16 YRVSHRTEYRYSDVVTSSYGRGFLTPCDSLRQRCVDHRLHIVPVPADSSISRDSYGNISS 75 Query: 67 AFSLDTDHTSLDVQADSWVALSARGQPQAQMAWDEAAMQMAYHGGRVMTPGMLEASNFLF 126 F + H +L V ++S V + P + + R + A+ F Sbjct: 76 YFHVTEPHCTLTVTSESIVDV----YPTPPELFTSGPASAPWEAARPTGRRGVLATEFTL 131 Query: 127 ESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVTEVFVNR 186 + + I E +YAA F P ++E +R L RI+ +F + +TT+ST V EV + R Sbjct: 132 DLNPPEITDEVRQYAAPSFEPQRPLIEVLRDLTTRIYADFTYRSGSTTISTGVNEVLLAR 191 Query: 187 RGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYCPGVNGA 246 GVCQDFA L ++CLR+ GLAA YVSGYL T+PPPG+ R++G D +HAW SV+ P +G Sbjct: 192 EGVCQDFARLAIACLRANGLAASYVSGYLATDPPPGKDRMVGIDVTHAWASVWTPQQSG- 250 Query: 247 EGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQS-MQVAVTVLPAE 302 + W+ DPTN D +I +G GRD++++ PLRG++ + S + VAV V P E Sbjct: 251 QCEWLGLDPTNDQLVDERYIVVGQGRDYVNVPPLRGIIYTNSENSVIDVAVDVAPCE 307 >Rv2569c [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Mtu Mycobacterium tuberculosis H37Rv Length = 314 Score = 196 bits (497), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 113/290 (38%), Positives = 159/290 (54%), Gaps = 5/290 (1%) Query: 1 MSERHIYRIHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDN 60 +S H YR+ H+T Y+Y+ V S+ LTPR Q C++H + I P P + D Sbjct: 11 LSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDG 70 Query: 61 FGNIIKAFSLDTDHTSLDVQADSWVALSARGQPQAQMAWDEAAMQMAYHGGRVMTPGMLE 120 +GNI F + H +L + +DS V +S P + A+Q PG L Sbjct: 71 YGNISSYFHVTEPHRTLTITSDSIVDVSP---PPPGLYTSGPALQPWEAARPAGLPGSL- 126 Query: 121 ASNFLFESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVT 180 A+ F + + I YAA F P ++E +R L RI+ +F + +TT+ST V Sbjct: 127 ATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTYRSGSTTISTGVN 186 Query: 181 EVFVNRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYC 240 EV + R GVCQDFA L ++CLR+ GLAA YVSGYL T+PPPG+ R+IG DA+HAW SV+ Sbjct: 187 EVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHAWASVWT 246 Query: 241 PGVNGAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQ 290 P G W+ DPTN D +I +G GRD+ D+ PLRG++ + Sbjct: 247 PQQPG-RFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSEN 295 >MT2645 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases MtC Mycobacterium tuberculosis CDC1551 Length = 314 Score = 196 bits (497), Expect = 7e-50, Method: Compositional matrix adjust. Identities = 113/290 (38%), Positives = 159/290 (54%), Gaps = 5/290 (1%) Query: 1 MSERHIYRIHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDN 60 +S H YR+ H+T Y+Y+ V S+ LTPR Q C++H + I P P + D Sbjct: 11 LSGTHRYRVTHRTEYRYSDVVTSSYGRGFLTPRNSLRQRCVAHRLTIDPAPADRSTSRDG 70 Query: 61 FGNIIKAFSLDTDHTSLDVQADSWVALSARGQPQAQMAWDEAAMQMAYHGGRVMTPGMLE 120 +GNI F + H +L + +DS V +S P + A+Q PG L Sbjct: 71 YGNISSYFHVTEPHRTLTITSDSIVDVSP---PPPGLYTSGPALQPWEAARPAGLPGSL- 126 Query: 121 ASNFLFESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVT 180 A+ F + + I YAA F P ++E +R L RI+ +F + +TT+ST V Sbjct: 127 ATEFTLDLNPPEITDAVREYAAPSFLPKRPLVEVLRDLASRIYTDFTYRSGSTTISTGVN 186 Query: 181 EVFVNRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYC 240 EV + R GVCQDFA L ++CLR+ GLAA YVSGYL T+PPPG+ R+IG DA+HAW SV+ Sbjct: 187 EVLLAREGVCQDFARLAIACLRANGLAACYVSGYLATDPPPGKDRMIGIDATHAWASVWT 246 Query: 241 PGVNGAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQ 290 P G W+ DPTN D +I +G GRD+ D+ PLRG++ + Sbjct: 247 PQQPG-RFEWLGLDPTNDQLVDQRYIVVGRGRDYADVPPLRGIIYTNSEN 295 >mll2875 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Mlo Mesorhizobium loti Length = 294 Score = 177 bits (448), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 103/296 (34%), Positives = 156/296 (52%), Gaps = 10/296 (3%) Query: 6 IYRIHHQTTYQYALPVRLSHQVLHLTPRELPW-QACLSHTVNIFPQPQLVRSYEDNFGNI 64 +Y I Y YA + + P + Q ++ +++ P P + D FGN Sbjct: 2 LYDIRLHLHYDYAAAAGGGRHQIRVLPSTISGVQRVIAASLSFTPAPNERSDFSDFFGNN 61 Query: 65 IKAFSLDTDHTSLDVQADSWVALSARGQPQAQMAWDEAAMQMAYHGGRVMTPGMLEASNF 124 + + + H +LD++ + V++S R +P ++ D ++ R + +F Sbjct: 62 VTSIAFRDAHDALDIRMSARVSVS-RPEPGLDVSPDIGRLRQELAAVRSLASA--SPHHF 118 Query: 125 LFESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVTEVFV 184 L S+H I YA + G S L RIH +F +D ATTV T ++ F Sbjct: 119 LAGSAHSGIDAAITSYAHDSVG--TSAAGTAMNLCNRIHRDFTYDGEATTVRTRASDAFK 176 Query: 185 NRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYCPGVN 244 +RGVCQDF+H+M++ LR +G+ A YVSG+L T PP G+PRL GADA HAWV V+C Sbjct: 177 LKRGVCQDFSHIMIAGLRGLGIPAGYVSGFLRTIPPKGKPRLEGADAMHAWVKVWC---- 232 Query: 245 GAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQSMQVAVTVLP 300 G + W + DPTNG+ HIT+G+GRD+ D++P+ GVL G Q + AV V+P Sbjct: 233 GRDAGWQEFDPTNGMRASNDHITVGYGRDYSDVAPIVGVLKTTGGQVGEQAVDVIP 288 >AGl1957 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 303 Score = 171 bits (433), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 96/298 (32%), Positives = 154/298 (51%), Gaps = 8/298 (2%) Query: 6 IYRIHHQTTYQYALPVRLSHQVLHLTPRELPW-QACLSHTVNIFPQPQLVRSYEDNFGNI 64 +Y + Y Y P + ++ + P +P Q ++ ++++ P P+ +ED F Sbjct: 13 LYDLSLHMGYTYDTPAHGARHIIRVLPLSIPGRQRLVAGSIDVSPTPEERVGFEDFFHQS 72 Query: 65 IKAFSLDTDHTSLDVQADSWVALSARGQPQAQMAWDEAAMQMAYHGGRVMTPGMLEASNF 124 + L H LD++ + V + A P + ++ V + +F Sbjct: 73 ATSVHLRAPHEKLDIRMQARVMVEA---PALTADFSPELSRLPRELAEVWSLDFQSPHHF 129 Query: 125 LFESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVTEVFV 184 + S + YA E PG+++ E RIH +F +D ATTV T +E F Sbjct: 130 VGTSPRIGSDAAISAYARELLKPGMTIREIALATCKRIHGDFTYDGEATTVDTTPSEAFK 189 Query: 185 NRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYCPGVN 244 + GVCQDF+H+M+ LRS+G+ A YVSG+L T PPPG+ RL GADA HAWV ++C Sbjct: 190 LKSGVCQDFSHIMIMALRSLGIPAGYVSGFLRTIPPPGKERLEGADAMHAWVRIWC---- 245 Query: 245 GAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQSMQVAVTVLPAE 302 G +++ DPTN + + HI +G+GRD+ D++P+ GVL G Q ++ AV V+P + Sbjct: 246 GEATGYLELDPTNDIVAGSDHIVVGYGRDYSDVAPVIGVLKSYGNQQIKQAVDVIPVQ 303 >SMc04058 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Sme Sinorhizobium meliloti Length = 292 Score = 158 bits (400), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 106/309 (34%), Positives = 153/309 (49%), Gaps = 34/309 (11%) Query: 6 IYRIHHQTTYQYALPVRLSHQVLHLTPRELPW-QACLSHTVNIFPQPQLVRSYEDNFGNI 64 +Y I + TY Y PV ++ + P +P Q ++ +V P P R D F N Sbjct: 2 LYDISLKITYGYEAPVSGGRHLVRVLPVSIPGRQRLVAGSVTCQPVPFERREGRDFFANP 61 Query: 65 IKAFSLDTDHTSLDVQADSWVALSARG------------QPQAQMAWD-EAAMQMAYHGG 111 + + H L ++ + V A P+ W +A + G Sbjct: 62 TTSILFRSVHDHLVIRMQARVQAEAPALTADLSPPLGGLAPELAACWSVDAESPHHFLGP 121 Query: 112 RVMTPGMLEASNFLFESSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPA 171 + P + E + + + + E I G +V + RIH +FA+D Sbjct: 122 SPLLPAVPEIAAYARAIARNTMTVEQI---------GAAVCD-------RIHRDFAYDSE 165 Query: 172 ATTVSTPVTEVFVNRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADA 231 ATTV+T E F +RGVCQDFAH+M+ LRS+G+ A YVSG+L T PPPGQ RL GADA Sbjct: 166 ATTVNTTPAEAFDLKRGVCQDFAHVMIVALRSLGIPAGYVSGFLRTLPPPGQERLEGADA 225 Query: 232 SHAWVSVYCPGVNGAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQS 291 HAWV +C G G W++ DPTN + T HI +G GRD+ D++P+ GVL G G+ + Sbjct: 226 MHAWVRFWC----GTTGGWMELDPTNNIPAGTDHIVVGHGRDYGDVAPVIGVLKGYGRHT 281 Query: 292 MQVAVTVLP 300 + AV V+P Sbjct: 282 TEQAVDVVP 290 >CC1600 Non COG Length = 325 Score = 144 bits (363), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 98/305 (32%), Positives = 143/305 (46%), Gaps = 24/305 (7%) Query: 6 IYRIHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDNFGNII 65 + I H T Y Y PVR S L + P++ Q +S +++ P Q+ SY D+FGN + Sbjct: 2 LLEIRHVTQYHYERPVRESLMELWMQPQKTARQRLVSFELDLNPAAQVF-SYADSFGNAV 60 Query: 66 KAFSLDTDHTSLDVQADSWVALSARGQPQAQM---AWDEAAMQMAYHGGRVMTPGMLEAS 122 F + H +L + A S V + G+ Q+ WD ++ + G E Sbjct: 61 YHFDVPQPHDNLTIIARSAVETESPGERPDQLDMGEWDR--LRSEFVRG--------ECF 110 Query: 123 NFLFESSHVRIKREFIRYAAECFGPGVSV---LEGVRTLMLRIHEEFAFDPAATTVSTPV 179 +FL VR + E + L VR+L I+ F + P T +P+ Sbjct: 111 DFLRPHGFVRTTEALQTFINEHDLDALKRRDPLTAVRSLSETIYGAFEYQPGVTDADSPI 170 Query: 180 TEVFVNRRGVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVY 239 RGVCQDFAH+ML+ R G+ ARYVSGYL T+ G DA+HAWV V+ Sbjct: 171 DLTLSAGRGVCQDFAHIMLAVCRGWGVPARYVSGYLFTDRDAGD--RSDPDATHAWVEVF 228 Query: 240 CPGVNGAEGSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQSMQVAVTVL 299 P + W+ DPTN + H+ + GRD+ D++P RGV G + + V V+V Sbjct: 229 LPSLR-----WVGFDPTNNMMAGERHVAVAVGRDYADVTPSRGVYKGDAESQLAVGVSVR 283 Query: 300 PAEEA 304 A A Sbjct: 284 RARAA 288 >SMb20888 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Sme Sinorhizobium meliloti Length = 272 Score = 143 bits (360), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 100/298 (33%), Positives = 143/298 (47%), Gaps = 32/298 (10%) Query: 8 RIHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDNFGNIIKA 67 +I H T Y Y PV+ + Q L LTP LP Q + + + + SY+D FGN Sbjct: 4 KISHTTEYHYDEPVQYALQRLRLTPVNLPGQT-VRNWKTLVDGAAIEVSYDDQFGNRTHL 62 Query: 68 FSLDTDHTSLDVQADSWVALSARGQPQAQMAWDEAAMQMAYHGGRVMTPGMLEASNFLFE 127 SLD D T+L ++A+ V D A + A+ P L A Sbjct: 63 VSLDADRTTLCIEANGEVETE-----------DRAGVFGAHQS---YVPLWLYARETPLT 108 Query: 128 SSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVTEVFVNRR 187 RI RE + A G + LE + LM IHE ++ T V T E + Sbjct: 109 KPGKRI-RELAKAAG-----GATELERMHALMAIIHETVRYEQGETQVGTSAEEALERGK 162 Query: 188 GVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYCPGVNGAE 247 GVCQD AH+++S R++GL ARYVSGYL+ E P Q ASHAW V+ G+ Sbjct: 163 GVCQDHAHILISAARTLGLPARYVSGYLMMEDHPQQT------ASHAWADVHIAGLG--- 213 Query: 248 GSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQSMQVAVTVLPAEEAQ 305 W+ DP N V PD ++ + G + D +P+ G++ G G ++++VAVTV ++Q Sbjct: 214 --WVGFDPANKVCPDDRYVRIASGLCYRDAAPVSGLVHGTGTETLKVAVTVEQQGQSQ 269 >DR1993 [E] COG1305 Transglutaminase-like enzymes, putative cysteine proteases Dra Deinococcus radiodurans Length = 274 Score = 134 bits (336), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 98/291 (33%), Positives = 138/291 (47%), Gaps = 26/291 (8%) Query: 9 IHHQTTYQYALPVRLSHQVLHLTPRELPWQACLSHTVNIFPQPQLVRSYEDNFGNIIKAF 68 I H T Y Y P S + L P + Q S +N+ P+ ++ S++D FG ++ Sbjct: 5 IRHTTEYHYPKPAWDSFNEVRLHPVQEVRQTLRSFHLNVTPEAEIT-SHKDYFGTLVHHV 63 Query: 69 SLDTDHTSLDVQADSWVALSARGQP-QAQMAWDEAAMQMAYHGGRVMTPGMLEASNFLFE 127 + HT L ++A + V A P A M+ E + P +E FL Sbjct: 64 HVHEAHTELRIEAQAIVDTHAVTLPLPAPMSVLED-----------VRPRNIE---FLVP 109 Query: 128 SSHVRIKREFIRYAAECFGPGVSVLEGVRTLMLRIHEEFAFDPAATTVSTPVTEVFVNRR 187 S V + GP + + L ++ F +D AT V+TP+ E + R Sbjct: 110 SPRVPAGDWPEIFEVRRPGPKDDLPSFLSDLNTFLYHRFTYDAKATGVNTPLAEFARHGR 169 Query: 188 GVCQDFAHLMLSCLRSIGLAARYVSGYLLTEPPPGQPRLIGADASHAWVSVYCPGVNGAE 247 GVCQDF H ML LR +G+ ARYVSGYL + G+ R GA+A+HAWV PG Sbjct: 170 GVCQDFTHAMLGILRQLGIPARYVSGYLYSG---GEMR--GAEATHAWVEALIPGY---- 220 Query: 248 GSWIDADPTNGVFPDTSHITLGWGRDFLDISPLRGVLIGGGQQSMQVAVTV 298 W+ DPTN HI + GR++ D+SP+RG GGGQ + VAV V Sbjct: 221 -GWLGYDPTNNRLAGEKHIKIAHGREYSDVSPVRGTYYGGGQGKLDVAVHV 270