BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0123.p (268 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2745 [E] COG0289 Dihydrodipicolinate reductase Rso Ralstonia ... 321 1e-87 NMB0203 [E] COG0289 Dihydrodipicolinate reductase Nme Neisseria ... 321 1e-87 NMA0066 [E] COG0289 Dihydrodipicolinate reductase NmA Neisseria ... 308 1e-83 STM0064 [E] COG0289 Dihydrodipicolinate reductase Sty Salmonella... 294 2e-79 YPO0480 [E] COG0289 Dihydrodipicolinate reductase Ype Yersinia p... 286 4e-77 dapB [E] COG0289 Dihydrodipicolinate reductase Eco Escherichia c... 286 4e-77 ZdapB [E] COG0289 Dihydrodipicolinate reductase EcZ Escherichia ... 285 9e-77 ECs0034 [E] COG0289 Dihydrodipicolinate reductase Ecs Escherichi... 285 9e-77 HI1308 [E] COG0289 Dihydrodipicolinate reductase Hin Haemophilus... 283 2e-76 PM0726 [E] COG0289 Dihydrodipicolinate reductase Pmu Pasteurella... 274 1e-73 >RSc2745 [E] COG0289 Dihydrodipicolinate reductase Rso Ralstonia solanacearum Length = 263 Score = 321 bits (822), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 164/264 (62%), Positives = 200/264 (75%), Gaps = 1/264 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKATGVLIESDL 63 + IA+AGASGRMG+MLI+ +L + LA ALD S ++G DAG LGKATGV++ DL Sbjct: 1 MKIAIAGASGRMGQMLIDTVLRTPGVTLAAALDRAGSDAVGQDAGARLGKATGVIVTDDL 60 Query: 64 ARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMAA 123 GL++ADVLIDFTRPE TL HLE GV VVIGTTGF E KA+ Y ++ A Sbjct: 61 RTGLSQADVLIDFTRPEATLAHLEIARELGVGVVIGTTGFTAEQKASFKDYGATIGVVWA 120 Query: 124 PNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKKL 183 PNMSVGVN T KL+E+AAK + GYD+EI+EAHH+ K+DAPSGTALKMGE++A+A G L Sbjct: 121 PNMSVGVNATFKLIEVAAKILAQGYDVEIVEAHHKHKIDAPSGTALKMGEIVAEAQGTTL 180 Query: 184 DDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAMG 243 + AVYAREG TG R +IGFATVRGGDI+GDHTVLF G GERIEI+H+S+SR SYA G Sbjct: 181 AERAVYAREGETGPRMNGTIGFATVRGGDIVGDHTVLFVGEGERIEITHRSNSRQSYAEG 240 Query: 244 SLRAARYLADKETGLYDMQDVLGF 267 ++RAA +LA K+ GL+DM DVLG Sbjct: 241 AVRAACFLAGKK-GLFDMNDVLGL 263 >NMB0203 [E] COG0289 Dihydrodipicolinate reductase Nme Neisseria meningitidis MC58 Length = 269 Score = 321 bits (822), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 164/268 (61%), Positives = 202/268 (75%), Gaps = 1/268 (0%) Query: 1 MTVLNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKATGVLIE 60 MT L IA+AGA+GRMGR+L+EA+ N D L+GAL+ S ++G DAG +G TG+ I Sbjct: 1 MTPLKIAIAGANGRMGRVLVEAVNNHPDTVLSGALEHSGSEALGLDAGYAVGLKTGIAIS 60 Query: 61 SDLARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAI 120 D+ LA++DVLIDFTRPE TLKHL+ C V ++IGTTGF+ GKAAI AEKT I Sbjct: 61 DDVDAVLAQSDVLIDFTRPEPTLKHLQKCVEKQVNIIIGTTGFDDTGKAAIHTAAEKTGI 120 Query: 121 MAAPNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALG 180 + A N SVGVN+T +L+ A+ + GYDIEIIE HHR KVDAPSGTAL+MGEVIA ALG Sbjct: 121 VFAANFSVGVNLTFHILDTVARVLNEGYDIEIIEGHHRHKVDAPSGTALRMGEVIAGALG 180 Query: 181 KKLDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSY 240 + L AVY REG TG RDPS+IGFATVR GDI+GDHT LFA GER+EI+HK+SSR+++ Sbjct: 181 RDLKQCAVYGREGHTGPRDPSTIGFATVRAGDIVGDHTALFATDGERVEITHKASSRMTF 240 Query: 241 AMGSLRAARYLADKETGLYDMQDVLGFK 268 A G++RAA ++ K TGLYDMQDVLG Sbjct: 241 AAGAVRAAVWVNGK-TGLYDMQDVLGLN 267 >NMA0066 [E] COG0289 Dihydrodipicolinate reductase NmA Neisseria meningitidis Z2491 Length = 269 Score = 308 bits (788), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 165/268 (61%), Positives = 202/268 (75%), Gaps = 1/268 (0%) Query: 1 MTVLNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKATGVLIE 60 MT L IA+AGA+GRMGR+L+EA+ N D L+GAL+ S ++G DAG +G TG+ I Sbjct: 1 MTPLKIAIAGANGRMGRVLVEAVNNHPDTVLSGALEHSGSEALGLDAGYAVGLKTGIAIS 60 Query: 61 SDLARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAI 120 D+ LA++DVLIDFTRPE TLKHL+ C V ++IGTTGF+ GKAAI A AEKT I Sbjct: 61 DDVDTVLAQSDVLIDFTRPEPTLKHLQKCVEKQVNIIIGTTGFDDAGKAAIRAAAEKTGI 120 Query: 121 MAAPNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALG 180 + A N SVGVN+T +L+ A + GYDIEIIE HHR KVDAPSGTAL+MGEVIA ALG Sbjct: 121 VFAANFSVGVNLTFHILDTVALVLNEGYDIEIIEGHHRHKVDAPSGTALRMGEVIAGALG 180 Query: 181 KKLDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSY 240 + L AVY REG TG RDPS+IGFATVR GDI+GDHT LFA GER+EI+HK+SSR+++ Sbjct: 181 RDLKQCAVYGREGHTGPRDPSTIGFATVRAGDIVGDHTALFATDGERVEITHKASSRMTF 240 Query: 241 AMGSLRAARYLADKETGLYDMQDVLGFK 268 A G++RAA ++ K TGLYDMQDVLG Sbjct: 241 AAGAVRAAVWVNGK-TGLYDMQDVLGLN 267 >STM0064 [E] COG0289 Dihydrodipicolinate reductase Sty Salmonella typhimurium LT2 Length = 273 Score = 294 bits (752), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 152/265 (57%), Positives = 191/265 (72%), Gaps = 1/265 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKA-TGVLIESD 62 + +A+AGA GRMGR LI+A + + +QL AL+ S +G+DAG G +GV+++S Sbjct: 6 IRVAIAGAGGRMGRQLIQAAMAMEGVQLGAALEREGSSLLGSDAGELAGAGKSGVIVQSS 65 Query: 63 LARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMA 122 L DV IDFTRPEGTL HL +C HG +VIGTTGF+ GK AI +++ AI+ Sbjct: 66 LEAVKDDFDVFIDFTRPEGTLTHLAFCRQHGKGMVIGTTGFDDAGKQAIREASQEIAIVF 125 Query: 123 APNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKK 182 A N SVGVNV +KLLE AAK DIEIIEAHHR KVDAPSGTAL MGE IA AL K Sbjct: 126 AANFSVGVNVMLKLLEKAAKVMGDYSDIEIIEAHHRHKVDAPSGTALAMGEAIAGALDKN 185 Query: 183 LDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAM 242 L D AVY+REG TGER +IGFATVR GDI+G+HT +FA IGER+EI+HK+SSR+++A Sbjct: 186 LKDCAVYSREGYTGERVAGTIGFATVRAGDIVGEHTAMFADIGERVEITHKASSRMTFAN 245 Query: 243 GSLRAARYLADKETGLYDMQDVLGF 267 G+LR+A +L K+ GL+DM+DVLG Sbjct: 246 GALRSALWLKTKKNGLFDMRDVLGL 270 >YPO0480 [E] COG0289 Dihydrodipicolinate reductase Ype Yersinia pestis Length = 273 Score = 286 bits (731), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 146/268 (54%), Positives = 189/268 (70%), Gaps = 1/268 (0%) Query: 2 TVLNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKAT-GVLIE 60 + + IA+ GA GRMGR LI+A+ + + L A++ S +G+DAG G V++ Sbjct: 4 STIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVG 63 Query: 61 SDLARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAI 120 DL++ DVLIDFTRPEGTL+HL C H +VIGTTGF+ GKAAI+ A I Sbjct: 64 DDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGI 123 Query: 121 MAAPNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALG 180 + A N SVGVNV +KLLE AAK DIEIIEAHHR KVDAPSGTAL MGE IADA+G Sbjct: 124 VFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIADAMG 183 Query: 181 KKLDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSY 240 + L D AVY+REG TGER P +IGFATVR GDI+G+HT +FA IGER+EI+HK++SR+++ Sbjct: 184 RSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSRMTF 243 Query: 241 AMGSLRAARYLADKETGLYDMQDVLGFK 268 A G++++A +L + GL+DM+DVL Sbjct: 244 AHGAVKSAIWLGKHDNGLFDMRDVLNLN 271 >dapB [E] COG0289 Dihydrodipicolinate reductase Eco Escherichia coli K12 Length = 273 Score = 286 bits (731), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 155/263 (58%), Positives = 190/263 (72%), Gaps = 1/263 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKA-TGVLIESD 62 + +A+AGA GRMGR LI+A L + +QL AL+ S +G+DAG G TGV ++S Sbjct: 6 IRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSS 65 Query: 63 LARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMA 122 L DV IDFTRPEGTL HL +C HG +VIGTTGF+ GK AI A AI+ Sbjct: 66 LDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVF 125 Query: 123 APNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKK 182 A N SVGVNV +KLLE AAK DIEIIEAHHR KVDAPSGTAL MGE IA AL K Sbjct: 126 AANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKD 185 Query: 183 LDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAM 242 L D AVY+REG TGER P +IGFATVR GDI+G+HT +FA IGER+EI+HK+SSR+++A Sbjct: 186 LKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFAN 245 Query: 243 GSLRAARYLADKETGLYDMQDVL 265 G++R+A +L+ KE+GL+DM+DVL Sbjct: 246 GAVRSALWLSGKESGLFDMRDVL 268 >ZdapB [E] COG0289 Dihydrodipicolinate reductase EcZ Escherichia coli O157:H7 EDL933 Length = 273 Score = 285 bits (728), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 155/263 (58%), Positives = 189/263 (71%), Gaps = 1/263 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKA-TGVLIESD 62 + +A+AGA GRMGR LI+A L + +QL AL+ S +G+DAG G TGV ++S Sbjct: 6 IRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSS 65 Query: 63 LARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMA 122 L DV IDFTRPEGTL HL +C HG +VIGTTGF+ GK AI A AI+ Sbjct: 66 LDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVF 125 Query: 123 APNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKK 182 A N SVGVNV +KLLE AAK DIEIIEAHHR KVDAPSGTAL MGE IA AL K Sbjct: 126 AANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKD 185 Query: 183 LDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAM 242 L D AVY+REG TGER P +IGFATVR GDI+G+HT +FA IGER+EI+HK+SSR+++A Sbjct: 186 LKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFAN 245 Query: 243 GSLRAARYLADKETGLYDMQDVL 265 G++R+A +L+ KE GL+DM+DVL Sbjct: 246 GAVRSALWLSGKENGLFDMRDVL 268 >ECs0034 [E] COG0289 Dihydrodipicolinate reductase Ecs Escherichia coli O157:H7 Length = 273 Score = 285 bits (728), Expect = 9e-77, Method: Compositional matrix adjust. Identities = 155/263 (58%), Positives = 189/263 (71%), Gaps = 1/263 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKA-TGVLIESD 62 + +A+AGA GRMGR LI+A L + +QL AL+ S +G+DAG G TGV ++S Sbjct: 6 IRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSS 65 Query: 63 LARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMA 122 L DV IDFTRPEGTL HL +C HG +VIGTTGF+ GK AI A AI+ Sbjct: 66 LDAIKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVF 125 Query: 123 APNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKK 182 A N SVGVNV +KLLE AAK DIEIIEAHHR KVDAPSGTAL MGE IA AL K Sbjct: 126 AANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAHALDKD 185 Query: 183 LDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAM 242 L D AVY+REG TGER P +IGFATVR GDI+G+HT +FA IGER+EI+HK+SSR+++A Sbjct: 186 LKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSRMTFAN 245 Query: 243 GSLRAARYLADKETGLYDMQDVL 265 G++R+A +L+ KE GL+DM+DVL Sbjct: 246 GAVRSALWLSGKENGLFDMRDVL 268 >HI1308 [E] COG0289 Dihydrodipicolinate reductase Hin Haemophilus influenzae Length = 270 Score = 283 bits (725), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 144/263 (54%), Positives = 186/263 (70%), Gaps = 1/263 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKA-TGVLIESD 62 L IA+AGA GRMG LI+A+ +A+ ++L A + S +GTDAG G GV + D Sbjct: 3 LKIAIAGAGGRMGCQLIQAVHSAEGVELGAAFERKGSSLVGTDAGELAGIGHLGVAVSDD 62 Query: 63 LARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMA 122 L K D+LIDFTRPEGTL+H+ +C A+ K+VIGTTGF+ GK AI A ++K AI+ Sbjct: 63 LESQKDKFDLLIDFTRPEGTLEHIAFCVANNKKMVIGTTGFDENGKVAIKAASDKIAIVF 122 Query: 123 APNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKK 182 A N SVGVN+ KLLE AAK DIE+IEAHHR KVDAPSGTAL MGE IA LG+ Sbjct: 123 ASNFSVGVNLVFKLLEKAAKVMGDYCDIEVIEAHHRHKVDAPSGTALSMGEHIAKTLGRD 182 Query: 183 LDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAM 242 L V+ REG+TGER IGF+T+R D++G+H+V FA IGER+EISHK+SSR+++A Sbjct: 183 LKTHGVFCREGITGERKRDEIGFSTIRASDVVGEHSVWFADIGERVEISHKASSRMTFAN 242 Query: 243 GSLRAARYLADKETGLYDMQDVL 265 G++RA ++L +K GL+DM DVL Sbjct: 243 GAVRAGKWLENKANGLFDMTDVL 265 >PM0726 [E] COG0289 Dihydrodipicolinate reductase Pmu Pasteurella multocida Length = 270 Score = 274 bits (701), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 141/263 (53%), Positives = 179/263 (68%), Gaps = 1/263 (0%) Query: 4 LNIAVAGASGRMGRMLIEAILNADDLQLAGALDTPTSPSIGTDAGLFLGKA-TGVLIESD 62 L +A+ GA GRMGR LI+A+ + + L A + S +G DAG GV I D Sbjct: 3 LRVAIVGAGGRMGRQLIQAVSETEGVVLGAAFERQGSSLLGADAGELANVGHLGVQITDD 62 Query: 63 LARGLAKADVLIDFTRPEGTLKHLEYCAAHGVKVVIGTTGFEPEGKAAIAAYAEKTAIMA 122 LA + D+LIDFTRPEGTL HL +C A +VIGTTGF+ +GKA I A+ I+ Sbjct: 63 LASQQDQFDLLIDFTRPEGTLAHLAFCVAQHKNMVIGTTGFDDDGKAKIQQAADSIGIVF 122 Query: 123 APNMSVGVNVTMKLLEMAAKNFSHGYDIEIIEAHHRFKVDAPSGTALKMGEVIADALGKK 182 A N SVGVN+ KLLE AAK DIEIIEAHHR KVDAPSGTAL MGE IA LG+ Sbjct: 123 ASNFSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKVDAPSGTALSMGEHIAKTLGRD 182 Query: 183 LDDVAVYAREGVTGERDPSSIGFATVRGGDIIGDHTVLFAGIGERIEISHKSSSRVSYAM 242 L V+ R+G+TGER IGFAT+R D++G+H+V FA IGER+EI+HK++SR+++A Sbjct: 183 LKTHGVFTRDGITGERKRDEIGFATIRASDVVGEHSVWFADIGERVEIAHKATSRMTFAK 242 Query: 243 GSLRAARYLADKETGLYDMQDVL 265 G++RAA++LA KE GL+DM DVL Sbjct: 243 GAVRAAKWLAQKEKGLFDMTDVL 265