BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0105.p (280 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2839 [S] COG3384 Uncharacterized conserved protein Pae Pseudom... 238 9e-63 RSc0015 [S] COG3384 Uncharacterized conserved protein Rso Ralsto... 184 2e-46 YPO0659 [S] COG3384 Uncharacterized conserved protein Ype Yersin... 183 3e-46 ZygiD [S] COG3384 Uncharacterized conserved protein EcZ Escheric... 171 2e-42 ECs3927 [S] COG3384 Uncharacterized conserved protein Ecs Escher... 171 2e-42 ygiD [S] COG3384 Uncharacterized conserved protein Eco Escherich... 169 7e-42 CC2958 Non COG 168 1e-41 STM3189 [S] COG3384 Uncharacterized conserved protein Sty Salmon... 165 1e-40 CAC0851 [S] COG3384 Uncharacterized conserved protein Cac Clostr... 160 4e-39 MA0486 [S] COG3384 Uncharacterized conserved protein Mac Methano... 143 5e-34 >PA2839 [S] COG3384 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 256 Score = 238 bits (608), Expect = 9e-63, Method: Compositional matrix adjust. Identities = 133/256 (51%), Positives = 162/256 (63%), Gaps = 2/256 (0%) Query: 11 LPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGNQAKPRVI 70 LP+L++SHGSPMLA+EPG +G L + LPRP+ I+VVS HWE+ RV A P + Sbjct: 2 LPTLYISHGSPMLALEPGASGVQLRRLATELPRPKAILVVSAHWESDDLRVTGAAVPDIW 61 Query: 71 HDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDGGWGLDHGAWVPLRYLYPQ 130 HDF GFPP LY + YPA G PALA+ + L+ GLPA D DHG WVPL +YPQ Sbjct: 62 HDFYGFPPPLYAVRYPAKGEPALAQRTIELLQAAGLPAQADPQRPFDHGTWVPLSLMYPQ 121 Query: 131 ADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRNDADSGDAP 190 AD+PV+QLSL S+ PA +VGQ L L EG+LL+GSGS THNL EL AP Sbjct: 122 ADIPVLQLSLPSRLGPALQSRVGQALRQLRGEGVLLIGSGSITHNLGELDWRAGPEAIAP 181 Query: 191 HTLQFLQWFLDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMGAADDWTQLVHL 250 +F W ++++QA D AL YR AP A RNHPSDEHLL LFFA GA ++ H Sbjct: 182 WAREFRDWMVEKLQADDEAALHDYRRQAPWAARNHPSDEHLLPLFFARGAGGGGMRVEH- 240 Query: 251 DSGSTYHSLRMDAFAF 266 SG T SL MD + F Sbjct: 241 -SGFTLGSLGMDIYRF 255 >RSc0015 [S] COG3384 Uncharacterized conserved protein Rso Ralstonia solanacearum Length = 296 Score = 184 bits (468), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 125/285 (43%), Positives = 159/285 (55%), Gaps = 33/285 (11%) Query: 11 LPSLFVSHGSPMLAVEPGRTGPLLAGIGATLP--RPRGIVVVSPHWETFTPRVGNQAKPR 68 LP L++SHGSPMLA +PG G LA +G + PR IVVVSPHW T P V + + Sbjct: 2 LPVLYLSHGSPMLAADPGPVGAALAALGRDVAALSPRAIVVVSPHWMTRRPAVTARPQQE 61 Query: 69 VIHDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGL--------PAHTDGGWGLDHGA 120 HDFGGFPP LY L+Y PGAP LAE + + L DG + D LDHGA Sbjct: 62 AWHDFGGFPPQLYALEYAPPGAPVLAERI-RTLIDGNIVPGLEEQASTVLDPRQPLDHGA 120 Query: 121 WVPLRYLYPQADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELR 180 W+PL + P+A +PV+Q+SL PA +G+ LAPL EG+L++GSGSFTHNLR L Sbjct: 121 WIPLMLMLPEATIPVVQVSLMPGLSPACQMAMGRTLAPLRDEGVLIIGSGSFTHNLRALM 180 Query: 181 RNDADSGDAPHTL-------QFLQWFLDRMQAGDRDALFG----YRTTAPHAVRNHPSDE 229 R +G A H + F +W ++ M G R F YR APHA HP+DE Sbjct: 181 RG---AGMAQHGVPVEPWVEAFREWMVEAMTEGIRTGDFATFCDYRARAPHAAHAHPTDE 237 Query: 230 HLLTLFFAMGAA--------DDWTQLVHLDSGSTYHSLRMDAFAF 266 HL+ L+ A+GAA Q H+ TY +L MD+F F Sbjct: 238 HLMPLYVALGAAMGQPEQATPGGVQARHVVDTVTYGALAMDSFRF 282 >YPO0659 [S] COG3384 Uncharacterized conserved protein Ype Yersinia pestis Length = 260 Score = 183 bits (465), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 106/262 (40%), Positives = 148/262 (56%), Gaps = 4/262 (1%) Query: 7 DSLPLPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGNQAK 66 ++ +P+LF+ HGSPM +E +G TLPRP+ I+ +S HW T V Sbjct: 2 NTFRMPALFLGHGSPMNVLEENSYTQAWRTLGETLPRPKMILAISAHWYTRGTAVTAMEH 61 Query: 67 PRVIHDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDGGWGLDHGAWVPLRY 126 PR IHDFGGFP AL+++ YPAPG+P LA H+ Q L + A T G WGLDHG+W L Sbjct: 62 PRTIHDFGGFPQALFDIQYPAPGSPELAAHIQQLLAPTPVRADT-GEWGLDHGSWGVLIK 120 Query: 127 LYPQADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRNDADS 186 +YP+AD+PV+QLS+ QP AYH+++GQ LA L ++G+++V SG+ HNLR L + +S Sbjct: 121 MYPEADIPVVQLSIDGTQPAAYHYELGQKLAALREQGVMIVASGNVVHNLR-LGKWQGES 179 Query: 187 GDAPHTLQFLQWFLDRMQ-AGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMGAADDWT 245 P F Q+ D + GD L + A+ N PS EH L L + +G+ D Sbjct: 180 SPYPWAESFNQFVRDNLSYQGDDHPLVNFMQHEGAALSN-PSPEHYLPLLYVLGSWDGKE 238 Query: 246 QLVHLDSGSTYHSLRMDAFAFG 267 + G SL M + G Sbjct: 239 PVSIPTDGVEMGSLSMLSVQIG 260 >ZygiD [S] COG3384 Uncharacterized conserved protein EcZ Escherichia coli O157:H7 EDL933 Length = 271 Score = 171 bits (433), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 107/268 (39%), Positives = 146/268 (54%), Gaps = 8/268 (2%) Query: 4 IAADSLPLPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGN 63 I S +P+LF+ HGSPM +E +G TLPRP+ IVVVS HW T V Sbjct: 8 IIMSSTRMPALFLGHGSPMNVLEDNLYTRSWQTLGMTLPRPQAIVVVSAHWFTRGTGVTA 67 Query: 64 QAKPRVIHDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDG-GWGLDHGAWV 122 P IHDFGGFP ALY+ YPAPG+PALA+ + + L +P D WG DHG+W Sbjct: 68 METPPTIHDFGGFPQALYDTHYPAPGSPALAQRLVELL--APIPVTLDKEAWGFDHGSWG 125 Query: 123 PLRYLYPQADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRN 182 L +YP AD+P++QLS+ S +P A+HF++G+ LA L EGI+LV SG+ HNLR ++ + Sbjct: 126 VLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIMLVASGNVVHNLRTVKWH 185 Query: 183 DADSGDAPHTLQFLQWF---LDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMG 239 DS P + F ++ L ++ L Y A+ N P+ EH L L + +G Sbjct: 186 -GDSSPYPWAMSFNEYVKANLTWQGPVEQHPLVNYLDHEGGALSN-PTPEHYLPLLYVLG 243 Query: 240 AADDWTQLVHLDSGSTYHSLRMDAFAFG 267 A D + G SL M + G Sbjct: 244 AWDGQEPITIPVDGIEMGSLSMLSVQIG 271 >ECs3927 [S] COG3384 Uncharacterized conserved protein Ecs Escherichia coli O157:H7 Length = 271 Score = 171 bits (433), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 107/268 (39%), Positives = 146/268 (54%), Gaps = 8/268 (2%) Query: 4 IAADSLPLPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGN 63 I S +P+LF+ HGSPM +E +G TLPRP+ IVVVS HW T V Sbjct: 8 IIMSSTRMPALFLGHGSPMNVLEDNLYTRSWQTLGMTLPRPQAIVVVSAHWFTRGTGVTA 67 Query: 64 QAKPRVIHDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDG-GWGLDHGAWV 122 P IHDFGGFP ALY+ YPAPG+PALA+ + + L +P D WG DHG+W Sbjct: 68 METPPTIHDFGGFPQALYDTHYPAPGSPALAQRLVELL--APIPVTLDKEAWGFDHGSWG 125 Query: 123 PLRYLYPQADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRN 182 L +YP AD+P++QLS+ S +P A+HF++G+ LA L EGI+LV SG+ HNLR ++ + Sbjct: 126 VLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIMLVASGNVVHNLRTVKWH 185 Query: 183 DADSGDAPHTLQFLQWF---LDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMG 239 DS P + F ++ L ++ L Y A+ N P+ EH L L + +G Sbjct: 186 -GDSSPYPWAMSFNEYVKANLTWQGPVEQHPLVNYLDHEGGALSN-PTPEHYLPLLYVLG 243 Query: 240 AADDWTQLVHLDSGSTYHSLRMDAFAFG 267 A D + G SL M + G Sbjct: 244 AWDGQEPITIPVDGIEMGSLSMLSVQIG 271 >ygiD [S] COG3384 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 271 Score = 169 bits (428), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 106/268 (39%), Positives = 144/268 (53%), Gaps = 8/268 (2%) Query: 4 IAADSLPLPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGN 63 I S +P+LF+ HGSPM +E +G TLPRP+ IVVVS HW T V Sbjct: 8 IIMSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVVVSAHWFTRGTGVTA 67 Query: 64 QAKPRVIHDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDG-GWGLDHGAWV 122 P IHDFGGFP ALY+ YPAPG+PALA+ + + L +P D WG DHG+W Sbjct: 68 METPPTIHDFGGFPQALYDTHYPAPGSPALAQRLVELL--APIPVTLDKEAWGFDHGSWG 125 Query: 123 PLRYLYPQADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRN 182 L +YP AD+P++QLS+ S +P A+HF++G+ LA L EGI+LV SG+ HNLR ++ + Sbjct: 126 VLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIMLVASGNVVHNLRTVKWH 185 Query: 183 DADSGDAPHTLQFLQWF---LDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMG 239 DS P F ++ L ++ L Y + N P+ EH L L + +G Sbjct: 186 -GDSSPYPWATSFNEYVKANLTWQGPVEQHPLVNYLDHEGGTLSN-PTPEHYLPLLYVLG 243 Query: 240 AADDWTQLVHLDSGSTYHSLRMDAFAFG 267 A D + G SL M + G Sbjct: 244 AWDGQEPITIPVEGIEMGSLSMLSVQIG 271 >CC2958 Non COG Length = 256 Score = 168 bits (426), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 106/237 (44%), Positives = 135/237 (56%), Gaps = 17/237 (7%) Query: 11 LPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETF-TPRVGNQAKPRV 69 +P LFV HGSPM A+E A +G LPRP+ I++VS HWET V A P Sbjct: 4 MPVLFVGHGSPMNAIEDNAWRRDWARLGRELPRPKAILMVSAHWETRGASAVSAAAAPET 63 Query: 70 IHDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDGGWGLDHGAWVPLRYLYP 129 IHDF GFP AL+++ YPAPG PALA VA L + H G LDHGAW L +YP Sbjct: 64 IHDFFGFPQALFDVCYPAPGDPALAARVADLLAPDTVVQHPTRG--LDHGAWGVLAPMYP 121 Query: 130 QADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLR--ELRRNDADSG 187 AD+PV+QLSL + +H++ G+ LAPL EG+L++GSG HNLR + RR Sbjct: 122 DADIPVVQLSLDRDRSDRWHYEAGRRLAPLRDEGVLIIGSGDIVHNLRAIDFRR------ 175 Query: 188 DAPHTLQFLQWFLDRMQ----AGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMGA 240 P TL + + F D + AGD D L +RT P A + S EH L L + +GA Sbjct: 176 --PETLPWAERFNDTAKQLILAGDHDPLIDWRTLGPDAEASINSAEHYLPLLYVLGA 230 >STM3189 [S] COG3384 Uncharacterized conserved protein Sty Salmonella typhimurium LT2 Length = 276 Score = 165 bits (417), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 97/236 (41%), Positives = 137/236 (58%), Gaps = 8/236 (3%) Query: 11 LPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGNQAKPRVI 70 +P+LF+ HGSPM ++ +G LPRP+ IVVVS HW T V +P+ + Sbjct: 20 MPALFLGHGSPMNVLDDNDYTRAWRRLGEALPRPQAIVVVSAHWYTRGTGVTAMERPQTL 79 Query: 71 HDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDG-GWGLDHGAWVPLRYLYP 129 HDFGGFP ALY+ YPAPG+PALA+ + + L +P D WG DHG+W L +YP Sbjct: 80 HDFGGFPQALYDTHYPAPGSPALAQRLVELL--APVPVALDKEAWGFDHGSWGVLIKMYP 137 Query: 130 QADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRNDADSGDA 189 AD+P++QLS+ S +P A+HF+VG+ LA L EG++LV SG+ HNLR +R + D+ Sbjct: 138 NADIPMVQLSVDSTKPAAWHFEVGRKLATLRDEGVMLVASGNVVHNLRTVRWH-GDNIPY 196 Query: 190 PHTLQ---FLQWFLDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMGAAD 242 P F++ L ++ L Y A+ N P+ EH L L + +GA D Sbjct: 197 PWAASFNDFVKANLTWQGPVEQHPLVNYLQHEGGALSN-PTPEHFLPLLYVLGAWD 251 >CAC0851 [S] COG3384 Uncharacterized conserved protein Cac Clostridium acetobutylicum Length = 255 Score = 160 bits (404), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 77/230 (33%), Positives = 135/230 (58%), Gaps = 4/230 (1%) Query: 14 LFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGNQAKP-RVIHD 72 +F+ HGSP L ++ + L +G+ + +PR IVV + H+E T + + + + IHD Sbjct: 5 MFICHGSPELILQDNQYTKCLQKLGSEI-KPRAIVVFTAHFEKETTTICFRDEAYKTIHD 63 Query: 73 FGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDGGWGLDHGAWVPLRYLYPQAD 132 F GF LY +DYPA G+ +A+ ++ L + D GLDHG W L+ ++P+AD Sbjct: 64 FYGFKDELYAVDYPAIGSKGVAKDISNLLNKRNIDNVFDEKRGLDHGTWSILKLMFPKAD 123 Query: 133 VPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRNDADSGDAPHT 192 VPV+Q+S+ P + +G+ + L+ + +L++GSG+ HNL+ L+ N +S Sbjct: 124 VPVVQISVNPYLPIDKQYNIGRAIRELSDKDVLVIGSGATVHNLKTLKWN--NSTPDIWA 181 Query: 193 LQFLQWFLDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMGAAD 242 ++F W +++++ D ++LF YR AP+A P +EH++ LF A+G+ + Sbjct: 182 VEFDDWIINKVKNKDLESLFNYRKLAPNAKIAVPREEHIVPLFIALGSGN 231 >MA0486 [S] COG3384 Uncharacterized conserved protein Mac Methanosarcina acetivorans str.C2A Length = 258 Score = 143 bits (360), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 79/234 (33%), Positives = 115/234 (49%), Gaps = 11/234 (4%) Query: 11 LPSLFVSHGSPMLAVEPGRTGPLLAGIGATLPRPRGIVVVSPHWETFTPRVGNQAKPRVI 70 +P LFV HGSPM A+E I + RP+ I+ +S H+E V + KP+ I Sbjct: 5 MPVLFVGHGSPMNAIEENEFTESWREISEKISRPKAILAISAHYEREDSSVTSNEKPKTI 64 Query: 71 HDFGGFPPALYELDYPAPGAPALAEHVAQRLRDGGLPAHTDGGWGLDHGAWVPLRYLYPQ 130 HDF GFP LY+ Y G+ L +++D D WG+DHG W L +YP Sbjct: 65 HDFYGFPKELYDQKYDCSGSKEL----ITKVKDLAQEVDFDSRWGIDHGVWCVLSKMYPN 120 Query: 131 ADVPVIQLSLQSQQPPAYHFQVGQLLAPLAKEGILLVGSGSFTHNLRELRRNDADSGDAP 190 AD+PV++LS+ + H+ + + L L +EGIL+ +G+ HNL R SG P Sbjct: 121 ADIPVVELSINRKLSMQQHYDLARKLYKLREEGILIFCTGNVVHNLMLARM----SG-TP 175 Query: 191 HTL--QFLQWFLDRMQAGDRDALFGYRTTAPHAVRNHPSDEHLLTLFFAMGAAD 242 + F + + A D L Y A+ + S EH + L +A+GA D Sbjct: 176 YKWASSFDEKVKKYVTARDDLKLVNYELLGEDALLSVNSAEHYIPLIYALGATD 229