BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0101.p (428 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value yjiZ [GEPR] COG0477 Permeases of the major facilitator superfami... 414 e-115 ECs5316 [GEPR] COG0477 Permeases of the major facilitator superf... 414 e-115 ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfam... 413 e-115 yhaU [GEPR] COG0477 Permeases of the major facilitator superfami... 223 7e-58 ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfam... 223 7e-58 ECs4005 [GEPR] COG0477 Permeases of the major facilitator superf... 223 7e-58 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 214 2e-55 dgoT [GEPR] COG0477 Permeases of the major facilitator superfami... 206 7e-53 BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superf... 206 1e-52 STM3827 [GEPR] COG0477 Permeases of the major facilitator superf... 205 2e-52 >yjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 453 Score = 414 bits (1065), Expect = e-115, Method: Compositional matrix adjust. Identities = 203/424 (47%), Positives = 285/424 (67%), Gaps = 8/424 (1%) Query: 6 EKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAY 65 ++S R+KRIQ A+ L A ++NYLDRS+LS+AN ++ +EL LSA+++G LLS FSLAY Sbjct: 31 QRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAY 90 Query: 66 AFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPA 125 +QLP G +LD+ G R+MLG GMF WS+ Q G V+N QF++ R+ +G+GEAP P Sbjct: 91 GIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPC 150 Query: 126 GAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVS 185 G KV+++WF ++ERG P G F A+STIG A++PPIL +ML GWR MF+ +GVLGI ++ Sbjct: 151 GVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLA 210 Query: 186 VGWYLFYRNRNEVQLTPSEVLYLADDHDNDPNANAK---LSWSEWKSLFTYRTTWGMLFG 242 +GWY+ YRNR V+LT E YL N + NA+ LS++EW+SLF RT WGM+ G Sbjct: 211 IGWYMLYRNREHVELTAVEQAYL-----NAGSVNARRDPLSFAEWRSLFRNRTMWGMMLG 265 Query: 243 FMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGM 302 F G+ Y WLYL WLP YL+ +L + TG + IP++FG GML +GY+ D L+K GM Sbjct: 266 FSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGM 325 Query: 303 PAIRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMAFVNMASGGAWALVSVAIP 362 I+SRK I AG+ + AFT+ ++ A++ I +A+ ++ A W L+ VA+ Sbjct: 326 APIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVA 385 Query: 363 RRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVYMFVVDK 422 R+ AS+GS+QNF ++ S AP+ITG +VD THSF AL+I V A AL Y+F+V + Sbjct: 386 SRMTASVGSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQ 445 Query: 423 PIES 426 PI Sbjct: 446 PIND 449 >ECs5316 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 453 Score = 414 bits (1064), Expect = e-115, Method: Compositional matrix adjust. Identities = 203/424 (47%), Positives = 286/424 (67%), Gaps = 8/424 (1%) Query: 6 EKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAY 65 ++S R+KRIQ A+ L A ++NYLDRS+LS+AN ++ +EL LSA+++G LLS FSLAY Sbjct: 31 QRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAY 90 Query: 66 AFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPA 125 +QLP G +LD+ G R+MLG GMF WS+ Q G V++ QF++ R+ +G+GEAP P Sbjct: 91 GIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPC 150 Query: 126 GAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVS 185 G KV+++WF ++ERG P G F A+STIG A++PPIL +ML GWR MF+ +GVLGI ++ Sbjct: 151 GVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLA 210 Query: 186 VGWYLFYRNRNEVQLTPSEVLYLADDHDNDPNANAK---LSWSEWKSLFTYRTTWGMLFG 242 +GWY+ YRNR V+LT E YL N + NA+ LS++EW+SLF RT WGM+ G Sbjct: 211 IGWYMLYRNREHVELTAVEQAYL-----NAGSVNARRDPLSFAEWRSLFRNRTMWGMMLG 265 Query: 243 FMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGM 302 F G+ Y WLYL WLP YL+ +L + TG + IP++FG GML +GY+ D L+K GM Sbjct: 266 FSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGM 325 Query: 303 PAIRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMAFVNMASGGAWALVSVAIP 362 I+SRK I AG+ + AFT+ ++ MA++ I +A+ ++ A W L+ VA+ Sbjct: 326 APIKSRKICIIAGMFCSAAFTLIVPQATTSMMAVLLIGMALFCIHFAGTSCWGLIHVAVA 385 Query: 363 RRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVYMFVVDK 422 R+ AS+GS+QNF ++ S AP+ITG +VD THSF AL+I V A AL Y+F+V + Sbjct: 386 SRMTASVGSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQ 445 Query: 423 PIES 426 PI Sbjct: 446 PIND 449 >ZyjiZ [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 453 Score = 413 bits (1061), Expect = e-115, Method: Compositional matrix adjust. Identities = 202/424 (47%), Positives = 286/424 (67%), Gaps = 8/424 (1%) Query: 6 EKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAY 65 ++S R+KRIQ A+ L A ++NYLDRS+LS+AN ++ +EL LSA+++G LLS FSLAY Sbjct: 31 QRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAY 90 Query: 66 AFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPA 125 +QLP G +LD+ G R+MLG GMF WS+ Q G V++ QF++ R+ +G+GEAP P Sbjct: 91 GIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPC 150 Query: 126 GAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVS 185 G KV+++WF ++ERG P G F A+STIG A++PPIL +ML GWR MF+ +GVLGI ++ Sbjct: 151 GVKVINDWFNIKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLA 210 Query: 186 VGWYLFYRNRNEVQLTPSEVLYLADDHDNDPNANAK---LSWSEWKSLFTYRTTWGMLFG 242 +GWY+ YRNR V+LT E YL N + NA+ LS++EW+SLF RT WGM+ G Sbjct: 211 IGWYMLYRNREHVELTAVEQAYL-----NAGSVNARRDPLSFAEWRSLFRNRTMWGMMLG 265 Query: 243 FMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGM 302 F G+ Y WLYL WLP YL+ +L + TG + IP++FG GML +GY+ D L+K GM Sbjct: 266 FSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGM 325 Query: 303 PAIRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMAFVNMASGGAWALVSVAIP 362 I+SRK I AG+ + AFT+ ++ MA++ I +A+ ++ A W L+ VA+ Sbjct: 326 APIKSRKICIIAGMFCSAAFTLIVPQATTSMMAVLLIGMALFCIHFAGTSCWGLIHVAVA 385 Query: 363 RRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVYMFVVDK 422 R+ AS+GS+QNF ++ S AP+ITG +VD THSF AL+I V A AL Y+F+V + Sbjct: 386 SRMTASVGSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQ 445 Query: 423 PIES 426 P+ Sbjct: 446 PLND 449 >yhaU [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 444 Score = 223 bits (568), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 146/437 (33%), Positives = 230/437 (52%), Gaps = 27/437 (6%) Query: 3 VQKEKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFS 62 V ++K R ++ + F++ A VNY DR+TLSIA V++EL LSA MG + SAF Sbjct: 6 VDEKKKGVHTRYLILLIIFIVTA--VNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFG 63 Query: 63 LAYAFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVN-------NLQQFLVARVFL 115 AY Q+P G +LDKFG++ + +F WS+ GFV+ + F + R L Sbjct: 64 WAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFM-RFML 122 Query: 116 GLGEAPQFPAGAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFV 175 G EAP FPA A++V+ WF +ERG + IF ++ AL P+L L ++GW +F Sbjct: 123 GFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFT 182 Query: 176 IMGVLGIAVSVGWY-LFYRNRNEVQLTPSEVLYLAD-------DHDNDPNANA---KLSW 224 +MGV+G ++ W L + + +++ E+ ++++ DH +A A KL + Sbjct: 183 VMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHY 242 Query: 225 SEWKSLFTYRTTWGMLFGFMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGT 284 K L + R G+ FG + + W +LTW P YL E+ +SI + G V IP + G Sbjct: 243 I--KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGF 300 Query: 285 LGMLSSGYIADGLMKRGMPAIRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMA 344 G + G +D L+KRG+ +RK PI G++ A I YT +TT+ ++ +A+A Sbjct: 301 AGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLAST-IILCNYTNNTTLVVML--MALA 357 Query: 345 FVNMASGG-AWALVSVAIPRRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALL 403 F G W ++S P+ +V G + N G + + P++ G +V + HSF AL+ Sbjct: 358 FFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALV 417 Query: 404 ISAAVAFAAALVYMFVV 420 A A + Y+FVV Sbjct: 418 FVGCSALMAMVCYLFVV 434 >ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 444 Score = 223 bits (568), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 146/437 (33%), Positives = 230/437 (52%), Gaps = 27/437 (6%) Query: 3 VQKEKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFS 62 V ++K R ++ + F++ A VNY DR+TLSIA V++EL LSA MG + SAF Sbjct: 6 VDEKKKGVHTRYLILLIIFIVTA--VNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFG 63 Query: 63 LAYAFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVN-------NLQQFLVARVFL 115 AY Q+P G +LDKFG++ + +F WS+ GFV+ + F + R L Sbjct: 64 WAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFM-RFML 122 Query: 116 GLGEAPQFPAGAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFV 175 G EAP FPA A++V+ WF +ERG + IF ++ AL P+L L ++GW +F Sbjct: 123 GFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFT 182 Query: 176 IMGVLGIAVSVGWY-LFYRNRNEVQLTPSEVLYLAD-------DHDNDPNANA---KLSW 224 +MGV+G ++ W L + + +++ E+ ++++ DH +A A KL + Sbjct: 183 VMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHY 242 Query: 225 SEWKSLFTYRTTWGMLFGFMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGT 284 K L + R G+ FG + + W +LTW P YL E+ +SI + G V IP + G Sbjct: 243 I--KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGF 300 Query: 285 LGMLSSGYIADGLMKRGMPAIRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMA 344 G + G +D L+KRG+ +RK PI G++ A I YT +TT+ ++ +A+A Sbjct: 301 AGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLAST-IILCNYTNNTTLVVML--MALA 357 Query: 345 FVNMASGG-AWALVSVAIPRRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALL 403 F G W ++S P+ +V G + N G + + P++ G +V + HSF AL+ Sbjct: 358 FFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALV 417 Query: 404 ISAAVAFAAALVYMFVV 420 A A + Y+FVV Sbjct: 418 FVGCSALMAMVCYLFVV 434 >ECs4005 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 444 Score = 223 bits (568), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 146/437 (33%), Positives = 230/437 (52%), Gaps = 27/437 (6%) Query: 3 VQKEKSPRLKRIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFS 62 V ++K R ++ + F++ A VNY DR+TLSIA V++EL LSA MG + SAF Sbjct: 6 VDEKKKGVHTRYLILLIIFIVTA--VNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFG 63 Query: 63 LAYAFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVN-------NLQQFLVARVFL 115 AY Q+P G +LDKFG++ + +F WS+ GFV+ + F + R L Sbjct: 64 WAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFM-RFML 122 Query: 116 GLGEAPQFPAGAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFV 175 G EAP FPA A++V+ WF +ERG + IF ++ AL P+L L ++GW +F Sbjct: 123 GFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFT 182 Query: 176 IMGVLGIAVSVGWY-LFYRNRNEVQLTPSEVLYLAD-------DHDNDPNANA---KLSW 224 +MGV+G ++ W L + + +++ E+ ++++ DH +A A KL + Sbjct: 183 VMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHY 242 Query: 225 SEWKSLFTYRTTWGMLFGFMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGT 284 K L + R G+ FG + + W +LTW P YL E+ +SI + G V IP + G Sbjct: 243 I--KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGF 300 Query: 285 LGMLSSGYIADGLMKRGMPAIRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMA 344 G + G +D L+KRG+ +RK PI G++ A I YT +TT+ ++ +A+A Sbjct: 301 AGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLLAST-IILCNYTNNTTLVVML--MALA 357 Query: 345 FVNMASGG-AWALVSVAIPRRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALL 403 F G W ++S P+ +V G + N G + + P++ G +V + HSF AL+ Sbjct: 358 FFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALV 417 Query: 404 ISAAVAFAAALVYMFVV 420 A A + Y+FVV Sbjct: 418 FVGCSALMAMVCYLFVV 434 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 214 bits (546), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 135/426 (31%), Positives = 227/426 (53%), Gaps = 9/426 (2%) Query: 1 MEVQKEKSPRLKRIQVVALSFLMLAGI-VNYLDRSTLSIANHSVSQELNLSASQMGLLLS 59 M+ ++ R K +VA LM A I +NY+DR+ LS A + +E +LSA +MG+++S Sbjct: 1 MQDTPQRGQRSKVRWLVA--GLMWAAIAINYIDRTVLSAAAPHIQKEFHLSAVEMGVVMS 58 Query: 60 AFSLAYAFSQLPIGAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGE 119 AF +YA QLP G + D+FG + +LG + WS+A G + + RV LG+GE Sbjct: 59 AFFWSYALLQLPAGILADRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGE 118 Query: 120 APQFPAGAKVVSEWFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGV 179 A +P+ A + S WF +ER IF + S +G A+A P++ L+++F W++ F + G Sbjct: 119 AGAYPSNAGITSRWFPKQERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGS 178 Query: 180 LGIAVSVGWYLFYRNR--NEVQLTPSEVLYLADDHDNDPNANAKLSWSEWKSLFTYRTTW 237 LGI V W L +R+ + +E+ ++ P A W L T+R W Sbjct: 179 LGIVWCVVWALVFRDSPAEHEGVNAAELAHI--QKGLPPARGADAPAMPWTKLLTHRNVW 236 Query: 238 GMLFGFMGVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGL 297 M GF + Y + ++TWLP YL ER + + G++ +P + +G+ +D + Sbjct: 237 AMCIGFFMINYNSYFFITWLPTYLVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRV 296 Query: 298 MKRGMPAIR-SRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMAFVNMASGGAWAL 356 G ++ +RK + GL+ A + + AA+ S +A++ + +A + +A+ WAL Sbjct: 297 YASGRLSLTATRKLFLVIGLVMASSIGL-AAFAQSAVVAVILLCIAKSGTTVAASQVWAL 355 Query: 357 VSVAIPRRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVY 416 + P V+ + +QN +GG + P++TG +V T SF+ AL+ SAA+ A L Y Sbjct: 356 PADVAPGNTVSMVAGLQNSVSNMGGVVGPIVTGAIVGATGSFIPALVFSAALIGLAILNY 415 Query: 417 MFVVDK 422 +F++ K Sbjct: 416 LFLLGK 421 >dgoT [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 445 Score = 206 bits (525), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 129/416 (31%), Positives = 215/416 (51%), Gaps = 12/416 (2%) Query: 13 RIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAYAFSQLPI 72 R + + L + + ++ Y+DR+ L++A+ + +E ++ ++MG + SAF+ Y Q+P Sbjct: 27 RRRYLTLVMIFITVVICYVDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPG 86 Query: 73 GAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPAGAKVVSE 132 G LD+ G+RV +F WSVA L GF L + R G+ EAP FP ++V+ Sbjct: 87 GWFLDRVGSRVTYFIAIFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTS 146 Query: 133 WFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVSVGWYLFY 192 WF ER G + + +G A P+L + W +F++ G +GI S+ W+ Y Sbjct: 147 WFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVY 206 Query: 193 R-NRNEVQLTPSEVLYLAD-------DHDNDPNANAKLSWSEWKSLFTYRTTWGMLFGFM 244 + R ++ +E+ Y+ D D A L+ +WK +F +R G+ G Sbjct: 207 QPPRLTKGISKAELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVF-HRKLIGVYLGQF 265 Query: 245 GVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGMPA 304 V +W +LTW P YL E+ ++ + G++ +P++ +G+L SG++AD L+++G Sbjct: 266 AVASTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSL 325 Query: 305 IRSRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMAFVNMASGGAWALVSVAIPRR 364 +RK PI GL+ + A YT M + ++LA F N + W+LVS P R Sbjct: 326 GFARKTPIICGLL-ISTCIMGANYTNDPMMIMCLMALAF-FGNGFASITWSLVSSLAPMR 383 Query: 365 LVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVYMFVV 420 L+ G + NF G LGG P++ G + Q + F AL+ +AVA AL Y+ +V Sbjct: 384 LIGLTGGVFNFAGGLGGITVPLVVGYLA-QGYGFAPALVYISAVALIGALSYILLV 438 >BS_ycbE [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 455 Score = 206 bits (523), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 137/419 (32%), Positives = 206/419 (49%), Gaps = 20/419 (4%) Query: 22 LMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAYAFSQLPIGAMLDKFGA 81 L L +NY DR+TLSI SV +L L + MG + SAF AY QLP G +LD+FG+ Sbjct: 25 LFLVTSINYADRATLSITGDSVQHDLGLDSVAMGYVFSAFGWAYVIGQLPGGWLLDRFGS 84 Query: 82 RVMLGAGMFIWSVAQLAGGFVNNLQQ------FLVARVFLGLGEAPQFPAGAKVVSEWFA 135 + ++ +F WS L G + R +GL EAP FP +VV+ WF Sbjct: 85 KTIIALSIFFWSFFTLLQGAIGFFSAGTAIILLFALRFLVGLSEAPSFPGNGRVVASWFP 144 Query: 136 MRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVSVGWY-LFYRN 194 ERG + F ++ + PP++ L SFGW +FV+MG+ GI ++V W Y Sbjct: 145 SSERGTASAFFNSAQYFAIVIFPPLMGWLTHSFGWHSVFVVMGIAGILLAVIWLKTVYEP 204 Query: 195 RNEVQLTPSEVLYLA--------DDHDNDPNANAKLSWSEWKSLFTYRTTWGMLFGFMGV 246 + ++ +E+ Y+ DD + +K W K L T R G+ + Sbjct: 205 KKHPKVNEAELAYIEQGGGLISMDDSKSKQETESK--WPYIKQLLTNRMLIGVYIAQYCI 262 Query: 247 IYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGMPAIR 306 + + +LTW P YL R +SI G+V +P + G G + G ++D L+K+G Sbjct: 263 TTLTYFFLTWFPVYLVQARGMSILEAGFVASLPALCGFAGGVLGGIVSDILLKKGRSLTF 322 Query: 307 SRKWPICAGLIGAGAFTIPAAYTPSTTMAIVYISLAMAFVNMASGGAWALVSVAIPRRLV 366 +RK PI AG++ + + I YT S + +V +SLA + G WA+VS P+ Sbjct: 323 ARKVPIIAGMLLSCSM-IVCNYTDSAWLVVVIMSLAFFGKGFGALG-WAVVSDTSPKECA 380 Query: 367 ASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVYMFVVDKPIE 425 G + N G + P+I G +V+ T SF AL+ A A AA L Y+ +V PI+ Sbjct: 381 GLSGGLFNTFGNIASITTPIIIGYIVNATGSFNGALVFVGANAIAAILSYLLLVG-PIK 438 >STM3827 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 445 Score = 205 bits (522), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 131/418 (31%), Positives = 217/418 (51%), Gaps = 16/418 (3%) Query: 13 RIQVVALSFLMLAGIVNYLDRSTLSIANHSVSQELNLSASQMGLLLSAFSLAYAFSQLPI 72 R + + L + + ++ Y+DR+ L++A+ + +E ++ ++MG + SAF+ Y Q+P Sbjct: 27 RRRYLTLVMIFITVVICYVDRANLAVASMHIQKEFGITKAEMGYVFSAFAWLYTLCQIPG 86 Query: 73 GAMLDKFGARVMLGAGMFIWSVAQLAGGFVNNLQQFLVARVFLGLGEAPQFPAGAKVVSE 132 G LD+ G+R+ +F WSVA L GF L + R G+ EAP FPA ++V+ Sbjct: 87 GWFLDRIGSRLTYFIAIFGWSVATLLQGFATGLLSLIGLRAITGIFEAPAFPANNRMVTS 146 Query: 133 WFAMRERGGPTGIFVASSTIGPALAPPILTILMLSFGWRMMFVIMGVLGIAVSVGWYLFY 192 WF ER G + + +G A P+L + W +F++ G +GI S+ W+ Y Sbjct: 147 WFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLVWFKVY 206 Query: 193 R-NRNEVQLTPSEVLYLAD-------DHDNDPNANAKLSWSEWKSLFTYRTTWGMLFGFM 244 + R L+ +E+ Y+ D D A L+ ++WK +F +R G+ G Sbjct: 207 QPPRLTKSLSQAELEYIRDGGGLVDGDAPAKKEARQPLTKADWKLVF-HRKLVGVYLGQF 265 Query: 245 GVIYMVWLYLTWLPAYLEHERHLSIARTGWVVVIPYIFGTLGMLSSGYIADGLMKRGMPA 304 V +W +LTW P YL E+ ++ + G++ +P++ G+L SG++AD L+K+G Sbjct: 266 AVNSTLWFFLTWFPNYLTQEKGITALKAGFMTTVPFLAAFFGVLLSGWLADKLVKKGFSL 325 Query: 305 IRSRKWPICAGLIGAGAFTIPAAYT--PSTTMAIVYISLAMAFVNMASGGAWALVSVAIP 362 +RK PI GL+ + A YT P MA++ I+ F N + W+L+S P Sbjct: 326 GVARKTPIICGLL-ISTCIMGANYTNDPLWIMALMAIAF---FGNGFASITWSLISSLAP 381 Query: 363 RRLVASLGSMQNFGGYLGGSLAPVITGVVVDQTHSFVNALLISAAVAFAAALVYMFVV 420 RL+ G M NF G LGG P++ G + Q++ F AL+ + VA AL Y+ +V Sbjct: 382 MRLIGLTGGMFNFIGGLGGISVPLVIGYLA-QSYGFAPALVYISVVALLGALSYILLV 438