BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0099.p (265 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00879 [K] COG1414 Transcriptional regulator Sme Sinorhizobium... 148 1e-35 AGc1276 [K] COG1414 Transcriptional regulator Atu Agrobacterium ... 132 1e-30 TM0065 [K] COG1414 Transcriptional regulator Tma Thermotoga mari... 127 2e-29 STM1842 [K] COG1414 Transcriptional regulator Sty Salmonella typ... 125 1e-28 YPO1714 [K] COG1414 Transcriptional regulator Ype Yersinia pestis 122 1e-27 kdgR [K] COG1414 Transcriptional regulator Eco Escherichia coli K12 119 1e-26 Z2874 [K] COG1414 Transcriptional regulator EcZ Escherichia coli... 118 2e-26 ECs2537 [K] COG1414 Transcriptional regulator Ecs Escherichia co... 117 2e-26 BH2137 [K] COG1414 Transcriptional regulator Bha Bacillus halodu... 117 4e-26 yagI [K] COG1414 Transcriptional regulator Eco Escherichia coli K12 115 1e-25 >SMc00879 [K] COG1414 Transcriptional regulator Sme Sinorhizobium meliloti Length = 284 Score = 148 bits (374), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 91/254 (35%), Positives = 135/254 (53%), Gaps = 4/254 (1%) Query: 15 AGTAAFSKFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQ 74 AGT K M VL+ +A D P + PR T++R+L L+ EG++V+ R+ Sbjct: 14 AGTGTLGKAMAVLEAVAMADRPQRFTDILQTVRQPRGTLHRLLGHLVEEGLLVQR-RDLS 72 Query: 75 YEVGPRLINLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQA 134 YE G RL+ A R+W + R A L L LT ETVHL + + ++Y++K+ES Q Sbjct: 73 YEPGLRLLKFAYRSWSGNRFREIAAPYLLHLHQLTGETVHLGLLREAEIIYVDKVESRQT 132 Query: 135 VRMDSRIGTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVED 194 VRM S+IG Y + +GKA L+ L +R+ + FTA TH + +L A++E+ Sbjct: 133 VRMSSQIGKASPAYCTGIGKAALSVLPGGELQRISTGMEFHPFTAQTHRSIESLLAEIEE 192 Query: 195 TRARGYAEDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQAC 254 R G+A DREE+EA+I C A I + V +SV+ P YR A+ Q + + Sbjct: 193 IRHDGHAFDREEHEAEICCVAAPISVPEHDLVGGISVTGPSYRVSFKQLTAWAQDVRKVA 252 Query: 255 ATISRKL---AGPG 265 A I ++ GPG Sbjct: 253 AEIEEEVRIRLGPG 266 >AGc1276 [K] COG1414 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 298 Score = 132 bits (331), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 86/240 (35%), Positives = 126/240 (52%), Gaps = 3/240 (1%) Query: 5 ALPPDDAARIAGTAAFSKFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEG 64 A+PP T K + +L+LIA + P+ + SG PR TV+R LA L+AEG Sbjct: 33 AVPPSHQKTENATGTLGKVVSLLELIALAEKPMRFTDVVEASGQPRGTVHRQLAHLVAEG 92 Query: 65 MVVENPRNKQYEVGPRLINLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMV 124 +V ++ ++ Y VG RL+ LA++AW +D+R A L L++ T+E+VHLAV + + Sbjct: 93 LV-DHAADQTYAVGLRLLQLAAKAWSGNDLRNVAAPHLSALQEATQESVHLAVLNGGQVT 151 Query: 125 YIEKLESPQAVRMDSRIGTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTE 184 Y++K+E +RM S++G Y + VGKA L+ L L + FT T Sbjct: 152 YLDKMEGRHTLRMHSQVGKTSPAYCTGVGKAALSLLPVDELAELAAGMEFHRFTEATLIT 211 Query: 185 LAALRADVEDTRARGYAEDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQ 244 AL ADV GY D +E+E I C A + VA +SV+ P YR DA+Q Sbjct: 212 PEALMADVAAICDNGYGFDLQEHEIGIHCVAAPVRARGRNFVAAISVTGPAYR--VDAEQ 269 >TM0065 [K] COG1414 Transcriptional regulator Tma Thermotoga maritima Length = 246 Score = 127 bits (320), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 78/237 (32%), Positives = 121/237 (51%), Gaps = 1/237 (0%) Query: 26 VLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRLINLA 85 +L I ++++++A Y+ + L +G V+ ++K+Y G +LI Sbjct: 10 ILDFIVKNPGDVSVSEIAEKFNMSVSNAYKYMVVLEEKGFVLRK-KDKRYVPGYKLIEYG 68 Query: 86 SRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRIGTRV 145 S R +IR A + L + T ETVHL + VYI+K+E Q++ M SR+G +V Sbjct: 69 SFVLRRFNIRDIAHDHLVDIMKRTGETVHLILKDGFEGVYIDKVEGEQSIPMVSRLGMKV 128 Query: 146 TLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYAEDRE 205 LYS++ GK+ LA + E + ++ + L+ T NT T L+ ++E R RGYA D E Sbjct: 129 DLYSTASGKSILAFVPEKELKEYLKIVELKPKTPNTITNPRVLKRELEKIRKRGYAVDNE 188 Query: 206 ENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACATISRKLA 262 ENE I C G I +G PVA VS+S + + + Y L + ISRKL Sbjct: 189 ENEIGIMCVGVPIFDHNGYPVAGVSISGVARKFTEEKIEEYSDVLKEKAEEISRKLG 245 >STM1842 [K] COG1414 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 263 Score = 125 bits (313), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 77/241 (31%), Positives = 126/241 (52%), Gaps = 1/241 (0%) Query: 22 KFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRL 81 K +LQ + ++ + I +L+ + TVYR L + G V + +++Y + +L Sbjct: 18 KVFGILQALGEE-REIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKL 76 Query: 82 INLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRI 141 L +RA D+ +A +R+L LT+ET+HL + S+VYI K++S +RM SRI Sbjct: 77 FELGARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRI 136 Query: 142 GTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYA 201 G R LYS+++GK LA + ++++ + + T T T AL +++ RA+GY Sbjct: 137 GRRNPLYSTAIGKVLLAWRDRDEVKQILDGVEYKQSTGRTITSTEALLPLLDEVRAQGYG 196 Query: 202 EDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACATISRKL 261 ED EE E + C G + GV +A +S+S P R + Q YV L A IS ++ Sbjct: 197 EDNEEQEEGLRCIGVPVFDRFGVVIAGLSISFPTLRFSEERLQEYVAMLHAAARKISEQM 256 Query: 262 A 262 Sbjct: 257 G 257 >YPO1714 [K] COG1414 Transcriptional regulator Ype Yersinia pestis Length = 263 Score = 122 bits (305), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 124/241 (51%), Gaps = 1/241 (0%) Query: 22 KFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRL 81 K +LQ + ++ + I +L+ P+ TVYR L + + G V + +++Y + +L Sbjct: 18 KVFGILQALGEE-REIGITELSQRVMMPKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKL 76 Query: 82 INLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRI 141 L ++A D+ +A +R+L + TRET+HL + S+VYI K++S +RM SRI Sbjct: 77 FELGAKALQNVDLIRSADIQMRELSNETRETIHLGALDEDSIVYIHKIDSMYNLRMHSRI 136 Query: 142 GTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYA 201 G R L+S+++GK LA + E ++ + T T AAL ++ R +G+ Sbjct: 137 GRRNPLHSTAIGKVLLAWRDRGEVEEILSHIEFTRSTKYTLDSTAALLPVLDKVREQGFG 196 Query: 202 EDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACATISRKL 261 ED EE E + C + GV +A +S+S P R D + YV+ L A IS ++ Sbjct: 197 EDIEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFAEDRKSDYVKSLHCAARNISEQM 256 Query: 262 A 262 Sbjct: 257 G 257 >kdgR [K] COG1414 Transcriptional regulator Eco Escherichia coli K12 Length = 263 Score = 119 bits (297), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 75/241 (31%), Positives = 123/241 (51%), Gaps = 1/241 (0%) Query: 22 KFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRL 81 K +LQ + ++ + I +L+ + TVYR L + G V + +++Y + +L Sbjct: 18 KVFGILQALGEE-REIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKL 76 Query: 82 INLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRI 141 L +RA D+ +A +R+L LT+ET+HL + S+VYI K++S +RM SRI Sbjct: 77 FELGARALQNVDLIRSADIQMRELSRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRI 136 Query: 142 GTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYA 201 G R LYS+++GK LA + ++++ + + T T T AL ++ R +GY Sbjct: 137 GRRNPLYSTAIGKVLLAWRDRDEVKQILEGVEYKRSTERTITSTEALLPVLDQVREQGYG 196 Query: 202 EDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACATISRKL 261 ED EE E + C + GV +A +S+S P R + Q YV L A IS ++ Sbjct: 197 EDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQM 256 Query: 262 A 262 Sbjct: 257 G 257 >Z2874 [K] COG1414 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 263 Score = 118 bits (295), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 123/241 (51%), Gaps = 1/241 (0%) Query: 22 KFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRL 81 K +LQ + ++ + I +L+ + TVYR L + G V + +++Y + +L Sbjct: 18 KVFGILQALGEE-REIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKL 76 Query: 82 INLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRI 141 L +RA D+ +A +R++ LT+ET+HL + S+VYI K++S +RM SRI Sbjct: 77 FELGARALQNVDLIRSADIQMREISRLTKETIHLGALDEBSIVYIHKIDSMYNLRMYSRI 136 Query: 142 GTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYA 201 G R LYS+++GK LA + ++++ + + T T T AL ++ R +GY Sbjct: 137 GRRNPLYSTAIGKVLLAWRDRDEVKQILEGVEYKRSTERTITSTEALLPVLDQVREQGYG 196 Query: 202 EDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACATISRKL 261 ED EE E + C + GV +A +S+S P R + Q YV L A IS ++ Sbjct: 197 EDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQM 256 Query: 262 A 262 Sbjct: 257 G 257 >ECs2537 [K] COG1414 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 263 Score = 117 bits (294), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 74/241 (30%), Positives = 123/241 (51%), Gaps = 1/241 (0%) Query: 22 KFMVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRL 81 K +LQ + ++ + I +L+ + TVYR L + G V + +++Y + +L Sbjct: 18 KVFGILQALGEE-REIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKL 76 Query: 82 INLASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRI 141 L +RA D+ +A +R++ LT+ET+HL + S+VYI K++S +RM SRI Sbjct: 77 FELGARALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRI 136 Query: 142 GTRVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYA 201 G R LYS+++GK LA + ++++ + + T T T AL ++ R +GY Sbjct: 137 GRRNPLYSTAIGKVLLAWRDRDEVKQILEGVEYKRSTERTITSTEALLPVLDQVREQGYG 196 Query: 202 EDREENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACATISRKL 261 ED EE E + C + GV +A +S+S P R + Q YV L A IS ++ Sbjct: 197 EDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQM 256 Query: 262 A 262 Sbjct: 257 G 257 >BH2137 [K] COG1414 Transcriptional regulator Bha Bacillus halodurans Length = 251 Score = 117 bits (292), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 76/240 (31%), Positives = 120/240 (50%), Gaps = 2/240 (0%) Query: 24 MVVLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRLIN 83 + ++ L+++ L + +AA + + Y++LA L+ G + ++ K+Y +G R + Sbjct: 9 LTIISLVSEHKQGLGVTDVAAKLSLTKSSAYKLLATLVEHGFIEQDEETKKYRLGYRYLE 68 Query: 84 LASRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRIGT 143 L++ + DIR A L QL T E VHL + MVYI+KLE + +R S+IG Sbjct: 69 LSATLLESIDIRRQARPFLEQLEATTNEVVHLVLYDQGEMVYIDKLEGTKTLRTHSKIGR 128 Query: 144 RVTLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYAED 203 R ++ +SVGK +A L E + L+ L T T T+ ++E R GY + Sbjct: 129 RAPIHCTSVGKVIMAYLPEKVQISLIERYGLPPHTERTITDKETFMKELEKIRLEGYGYE 188 Query: 204 REENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQAYVQPLLQACA-TISRKLA 262 EENE I C A I G A VS+S P RL + ++PL+ A IS++L Sbjct: 189 MEENEPGITCIAAPIFDYQGAITAAVSISGPSI-RLSKERLHELRPLIIAIGKKISQRLG 247 >yagI [K] COG1414 Transcriptional regulator Eco Escherichia coli K12 Length = 252 Score = 115 bits (287), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 77/240 (32%), Positives = 118/240 (49%), Gaps = 2/240 (0%) Query: 26 VLQLIADQDAPLNIAQLAALSGYPRPTVYRILAALMAEGMVVENPRNKQYEVGPRLINLA 85 +L L +Q L I ++ L G + T++ +L L G + +NP N +Y +G +L+ Sbjct: 13 ILDLFNEQATELKITDISKLMGLSKSTLHSLLKTLQLHGYIDQNPENGKYRLGMKLVERG 72 Query: 86 SRAWDRSDIRTTAIESLRQLRDLTRETVHLAVPSDHSMVYIEKLESPQAVRMDSRIGTRV 145 DIR A L +L T +T HL + VYIEK+E A SRIG R+ Sbjct: 73 HFVVGSIDIRQKAKGWLTELSRRTGQTTHLGILDGREGVYIEKIEGKLAAIAYSRIGRRL 132 Query: 146 TLYSSSVGKAYLAGLEEAHRERLMRTLHLQAFTANTHTELAALRADVEDTRARGYAEDRE 205 ++++++GK +A L EA L+ FT T AL + + TR +GYA D E Sbjct: 133 PVHATAIGKVLIAWLGEAELNALLEGYQYTTFTPATLASREALMSALAQTREQGYALDSE 192 Query: 206 ENEAQIFCYGAAIVGADGVPVACVSVSIPLYRRLPDAQQA-YVQPLLQACATISRKLAGP 264 ENE + C + + +A +S+S L R+ DA+ A + + L QA +SR L P Sbjct: 193 ENEQGVRCVAVPVWNHESRVIAALSLS-TLTSRVDDAELANFREQLQQAGLALSRALGYP 251