BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0060.p (450 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 343 6e-94 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 341 2e-93 RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 337 3e-92 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 315 2e-85 RSp0182 [GEPR] COG0477 Permeases of the major facilitator superf... 302 1e-81 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 292 1e-78 STM1107 [GEPR] COG0477 Permeases of the major facilitator superf... 274 4e-73 CC2354 [GEPR] COG0477 Permeases of the major facilitator superfa... 262 2e-69 YPO1768 [GEPR] COG0477 Permeases of the major facilitator superf... 256 9e-68 PA2214 [GEPR] COG0477 Permeases of the major facilitator superfa... 253 5e-67 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 343 bits (879), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 183/410 (44%), Positives = 252/410 (61%), Gaps = 10/410 (2%) Query: 12 SATPSLASQAE--DAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAMY 69 +A P+ A E ++Y V RI+PFL CY+ ++LDRINIGFA+LQM+ DL SDA Y Sbjct: 4 NAIPAQAHSGERSTSVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAY 63 Query: 70 GLGAAIFYVGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRFL 129 GLGA IF+ GY+LFEVPSN+ L + GARRT SRI++LWG+ S M+ VTD FY LRFL Sbjct: 64 GLGAGIFFFGYMLFEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFL 123 Query: 130 LGVFEAGFFPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGL 189 LGVFEAGF PG++ YL+ W+ R A MA+ + GV+GG S WIM AG GL Sbjct: 124 LGVFEAGFAPGMIYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGL 183 Query: 190 YGWQWMFAIEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSGH 249 GWQWMF EG P++LLG+ A L D PA A+WL+ +++ + + A G Sbjct: 184 AGWQWMFLAEGIPSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARAA------PGQ 237 Query: 250 SLAALRQALSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIKDVVEVSLYSVIPNAI 309 + ++ +AL+ Y+ A YF L CG + FW+P +++ G+ D+ ++ LYS IPN Sbjct: 238 A-SSFGKALTEPKLYVLAAAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLA 296 Query: 310 GAVGLILIARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFAA 369 V + + RRSDRR ERH H A+ GA L A + +SF +L +++A+ IFA+ Sbjct: 297 MIVAMYALGRRSDRRGERHLHSAITAVLGA-GLLAWAAYATSFPAALISITLASAAIFAS 355 Query: 370 LPIFWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMD 419 +FW++P L A GIA I+S+G+ G SP LIG K TG++ Sbjct: 356 YSVFWAIPQQHLKGTAAAGGIALINSIGLFGGFFSPTLIGWTKEATGSLQ 405 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 341 bits (875), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 184/439 (41%), Positives = 265/439 (60%), Gaps = 11/439 (2%) Query: 12 SATPSLAS----QAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDA 67 S+T SL+ Q E+ YRK ++P L +CYV+++LDR+N+GFA+LQM DL FSD Sbjct: 4 SSTESLSQPTQLQEENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDT 63 Query: 68 MYGLGAAIFYVGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLR 127 +YGLGA +F++GY E+PSN+ L R GAR +RIM+ WG+ S M VT FY +R Sbjct: 64 VYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMR 123 Query: 128 FLLGVFEAGFFPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVM 187 FLLGV EAGFFPGI+LY+SYWF + RR V +F V ++G++G +SGWIM+ G Sbjct: 124 FLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQ 183 Query: 188 GLYGWQWMFAIEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVS 247 G GWQWMF +EG P+VL+G+L I+ L D A WL+ +E+ LQ + EA H Sbjct: 184 GYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYAH-- 241 Query: 248 GHSLAALRQALSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIKDVVEVSLYSVIPN 307 + LR A +L IYF L G T+ FW+P +IRD G+KD++ + + IP+ Sbjct: 242 ----SRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPS 297 Query: 308 AIGAVGLILIARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIF 367 A AV +I+++R +DR ER H A+ GA+ + T + V++ L++ A+ Sbjct: 298 AAAAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGAL 357 Query: 368 AALPIFWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMDIALYILAG 427 + +P+FWSLP L A GIAFI+S G G V+P+++G +K T + + I++ Sbjct: 358 STIPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIIST 417 Query: 428 LLLLSGLAMWSLIPRKAAT 446 L + G A+ LIP KA Sbjct: 418 TLFI-GAALVFLIPAKAVN 435 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 337 bits (865), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 184/432 (42%), Positives = 265/432 (61%), Gaps = 6/432 (1%) Query: 3 TPSPGGATLSATPSLASQAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDL 62 TP G + + P AS E+A YRKV R+IPFL +CYVV++LDR+N+GFA+LQM DL Sbjct: 5 TPPLGPSAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDL 64 Query: 63 GFSDAMYGLGAAIFYVGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAH 122 FS+ +YGLGA IF++GY LFEVPSN+ L R GAR +RIM+ WGL S MM VT A Sbjct: 65 KFSETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAM 124 Query: 123 FYTLRFLLGVFEAGFFPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRD 182 FY +RFLLG+ EAGFFPGI+LYL+YW+ A RR F VA++GV+GG +SGW ++ Sbjct: 125 FYVMRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKT 184 Query: 183 MAGVMGLYGWQWMFAIEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALR 242 GV GL GWQWMF IEG P+V++GL + L + + A+WL+ EE++ L E + Sbjct: 185 FGGVYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQ 244 Query: 243 THHVSGHSLAALRQALSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIKDVVEVSLY 302 A + ++ +L + IYF+ G ++FW+P +I+ G+ D + V L Sbjct: 245 KED------APIAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLL 298 Query: 303 SVIPNAIGAVGLILIARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLSVA 362 + IP V ++L+AR +DR ER H A+ GA+ L + ++ +++ L++ Sbjct: 299 TAIPYGAAVVAMVLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLG 358 Query: 363 AVLIFAALPIFWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMDIAL 422 + I LP+FWSLP L A GIA I+S+G +G +SP+ +G +K T + D + Sbjct: 359 TMGILTTLPLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGM 418 Query: 423 YILAGLLLLSGL 434 Y+LA ++L L Sbjct: 419 YLLAASMVLGAL 430 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 315 bits (806), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 171/431 (39%), Positives = 253/431 (58%), Gaps = 9/431 (2%) Query: 4 PSPGGATLSATPSLASQ---AEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQ 60 P PG + + + + E+ YRKV RIIP L ICY++++LDR+N+GFA+LQM + Sbjct: 12 PLPGVKAMKNSNTAITSPEVVENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSE 71 Query: 61 DLGFSDAMYGLGAAIFYVGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDA 120 +LGFS+A+YGLGA +F++GY FE+PSN+ L + GAR +RIM+ WGL S V Sbjct: 72 ELGFSEAIYGLGAGLFFIGYFFFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTE 131 Query: 121 AHFYTLRFLLGVFEAGFFPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIM 180 FY LRFLLG EAGF+PG++LYL+YWF + RR + A+F AG AG+ G +SGWIM Sbjct: 132 WQFYILRFLLGAAEAGFYPGVILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIM 191 Query: 181 RDMAGVMGLYGWQWMFAIEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEA 240 G GWQWMF +E PAV+LG++ + L + AKWL+ EE++ + EA Sbjct: 192 DQFHDTAGWQGWQWMFVLEAIPAVVLGVVILLYLDNSVKAAKWLTEEEKAIIS--RDIEA 249 Query: 241 LRTHHVSGHSLAALRQALSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIKDVVEVS 300 + HSL +L + + ++ IYF G L WMP +IR G+ V + Sbjct: 250 DSKGKAASHSLMSL---VKNPMLWVMMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIG 306 Query: 301 LYSVIPNAIGAVGLILIARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLS 360 L IP + +++ +R +D ER H V GA+ + ++ VS+ LS Sbjct: 307 LLGAIPFICAIIAMVIFSRSADHYRERRWHLVVPALLGAVGF-VVAASATNTTVSIIFLS 365 Query: 361 VAAVLIFAALPIFWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMDI 420 +AA + A P+FWSLP +L A GIA I+SV +G +SP+++G+++ T + ++ Sbjct: 366 MAAAGVLACAPLFWSLPTAILSGAAAAAGIALINSVANLAGFISPYMVGIIRDATHSSEL 425 Query: 421 ALYILAGLLLL 431 +Y+LAG L+L Sbjct: 426 GMYVLAGFLIL 436 >RSp0182 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 453 Score = 302 bits (773), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 180/398 (45%), Positives = 237/398 (59%), Gaps = 10/398 (2%) Query: 18 ASQAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAIFY 77 A+ E AI RK+ RI+PF+F Y++S+LDR NIG+A LQM Q+L S +G + IF+ Sbjct: 22 AAPDERAIVRKITWRILPFVFALYIISYLDRANIGYAALQMNQELALSSEAFGFVSGIFF 81 Query: 78 VGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRFLLGVFEAGF 137 +GY LFEVPSN+ L RFGARR +RI+V WGL ++G V A Y LRFLLGV EAGF Sbjct: 82 IGYFLFEVPSNLMLNRFGARRWIARILVTWGLVAMGSAFVQSATQLYALRFLLGVAEAGF 141 Query: 138 FPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFA 197 FPGI++YL+YWF AR A +A+F A + V+ V+G +S WIM D + GW+WM Sbjct: 142 FPGIIVYLTYWFRARELATTVALFTAAIPVSYVVGAPLSTWIM-DHVHWLQWSGWRWMLL 200 Query: 198 IEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSGHSLAALRQA 257 +EGAPAV+ GLL LAD P A+WLS ER +L A +++ R + LA L+ Sbjct: 201 LEGAPAVIGGLLCYGYLADRPKDARWLSEAERDWLLAELERD--RKARPAAAHLATLKVM 258 Query: 258 LSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIK-DVVEVSLYSVIPNAIGAVGLIL 316 R YL AFIYF CGSL + +WMP +I+ F EV L +++P +I Sbjct: 259 THPRVLYL-AFIYFVYQCGSLGIGYWMPQIIKGFSSALSHTEVGLIAMLPYVFATAVMIW 317 Query: 317 IARRSDRRNERHGHFAVCTTGGALAL--AALTLHPSSFAVSLGLLSVAAVLIFAALPIFW 374 +RRSD R ER H AV ALA A HP AV++ +LS++ ++A FW Sbjct: 318 WSRRSDLRAERRLHSAVPLGVAALAFVGAGFIGHP---AVAMAMLSLSLAGLYAFKSPFW 374 Query: 375 SLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVK 412 +LP L T A IA I+SVG G V P+ IG K Sbjct: 375 ALPTLFLTRSTAAVSIAVINSVGNLGGFVGPFAIGYFK 412 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 292 bits (747), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 171/407 (42%), Positives = 236/407 (57%), Gaps = 6/407 (1%) Query: 9 ATLSATPSLASQAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAM 68 +T S S D+ + +V R++P L +CYV + LDRINIGFA+LQM DL FSD + Sbjct: 2 STASTLNSTTLPLSDSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTV 61 Query: 69 YGLGAAIFYVGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRF 128 YGLGA +F++ Y LF +PSN+ L R G RR + +M++WG S M+ V A FY LRF Sbjct: 62 YGLGAGLFFIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRF 121 Query: 129 LLGVFEAGFFPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMG 188 LLGV EAGFFPGI++YL+ WF ARRR + A+F V +AGV+GG +SGWI+ +G Sbjct: 122 LLGVAEAGFFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHDALG 181 Query: 189 LYGWQWMFAIEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSG 248 L GWQWMF IEG P VLLG++ L + + WLS E++ L+ E R Sbjct: 182 LRGWQWMFLIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQR------ 235 Query: 249 HSLAALRQALSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIKDVVEVSLYSVIPNA 308 ++ + S+ +L IYFA+ T+ FWMP +I GI + + S +P Sbjct: 236 KTITSFSGIFSNPQVWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYL 295 Query: 309 IGAVGLILIARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFA 368 G +I I R SDR ER H + A L+ L P+S + +G L +A + A Sbjct: 296 AGCAFMIFIGRSSDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASA 355 Query: 369 ALPIFWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRT 415 ALP+FW LPP L + T+A GIA ISS G + ++P+LIG ++ T Sbjct: 356 ALPMFWQLPPAFLSSATLAAGIALISSFGSIAAFLAPYLIGWMRDTT 402 >STM1107 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 458 Score = 274 bits (700), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 165/436 (37%), Positives = 246/436 (56%), Gaps = 14/436 (3%) Query: 19 SQAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAIFYV 78 S + + K++ R+I FLF+ ++ SFLDRINIGFA L M QDLG S M+GL +FY Sbjct: 22 STGQQTVINKLFRRLIVFLFVLFIFSFLDRINIGFAGLTMGQDLGLSATMFGLATTLFYA 81 Query: 79 GYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRFLLGVFEAGFF 138 YV+F +PSN+ L+ GAR + IMVLWG+AS M Y LR L+G+ EAGF Sbjct: 82 TYVIFGIPSNVMLSIVGARHWIATIMVLWGIASTATMFAVGPKSLYVLRMLVGITEAGFL 141 Query: 139 PGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAI 198 PGI+LYL+YWF A RA A+F + LG +VSG+I+ + G+ L+GWQW+F + Sbjct: 142 PGILLYLTYWFPAFFRARANALFMIAMPATTALGSIVSGYIL-SLDGIFNLHGWQWLFLL 200 Query: 199 EGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSGH-SLAALRQA 257 EG P+VLLG++ F L D PA+AKWL+ E++ LQ + L G S A++Q Sbjct: 201 EGFPSVLLGIMVWFYLDDTPAKAKWLTAEDKKCLQEMMDSDRLTLVQPEGAISHNAMQQR 260 Query: 258 LSHRTTY-----LFAFIYFALTCGSLTLNFWMPLMIRDFGI-KDVVEVSLYSVIPNAIGA 311 R + ++ YF LT ++ W P +++ F + + L + IP Sbjct: 261 SLWREVFTPIVLMYTLAYFCLTNTLSAISIWTPQILKSFNEGSSNITIGLLAAIPQICTI 320 Query: 312 VGLILIARRSDRRNERHGHFAV--CTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFAA 369 +G+I +R SD+ ER H A+ LA+ T H + LG++ +A+ F+A Sbjct: 321 LGMIYWSRHSDKHQERKHHTALPFLFAAAGWLLASATDH--NLIQLLGIV-MASTGSFSA 377 Query: 370 LPIFWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMDIALYILAGLL 429 + IFW+ P + + A GIA I++ G +SP++IG +K TG+ + L+ +A LL Sbjct: 378 MAIFWTTPDQSISLRARAIGIAVINATGNIGSALSPFMIGWLKDITGSFNSGLWFVASLL 437 Query: 430 LLSGLAMWSLIPRKAA 445 ++ +W LIP KA+ Sbjct: 438 VVGAAIIW-LIPMKAS 452 >CC2354 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 430 Score = 262 bits (669), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 156/417 (37%), Positives = 240/417 (57%), Gaps = 7/417 (1%) Query: 18 ASQAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAIFY 77 +S E A +V R++P + Y+++++DR N+ +A+L M LG S+A YGLGA++F+ Sbjct: 5 SSALERATVGRVTRRLMPLFCLMYLIAYIDRQNVSYAKLDMVSALGLSEAAYGLGASLFF 64 Query: 78 VGYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRFLLGVFEAGF 137 +GY LFE P+N+ LAR GAR F+RIM WGL ++ + +AA FY LRFLLGV EAGF Sbjct: 65 IGYFLFEAPANLILARVGARVWFARIMFSWGLVTLALGFTQNAAMFYVLRFLLGVAEAGF 124 Query: 138 FPGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFA 197 FPG++ L+ W+ RA ++ +F A A +G + G ++ M G +GL GWQW+F Sbjct: 125 FPGVLYVLTLWYPQAHRARMVGLFMIASAFANAVGAAIGG-LLLGMDGFLGLAGWQWVFL 183 Query: 198 IEGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSGHSLAALRQA 257 + GAPAVLL ++ L GP+ A+WL E+S+L + E R V H A +A Sbjct: 184 VTGAPAVLLAPYVLWRLPSGPSDARWLPDVEKSWLASTLAAE--RGGEVDDHRGA--WKA 239 Query: 258 LSHRTTYLFAFIYFALTCGSLTLNFWMPLMIRDFGIKDVVEVSLYSVIPNAIGAVGLILI 317 + + A +Y + + L++W+P +++ FG+ + V +VIP + AV L + Sbjct: 240 IFDPRVLMLAGLYIGMPLSAYGLSYWLPTIVKSFGVSNTVN-GFINVIPWLLVAVALWFV 298 Query: 318 ARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLP 377 R + R H A A+AL+ + P + A+ +L +AA IFAA P+FWSLP Sbjct: 299 PRHAARHGASAWHIAGPVLLAAVALSLSVILPGA-ALKFTMLCIAAPAIFAAQPVFWSLP 357 Query: 378 PGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMDIALYILAGLLLLSGL 434 P L A GIA I++VG G ++ L+ +V+ TG+ + LA +LL++ L Sbjct: 358 PSFLSGPRAAAGIATINAVGNLGGFIAQNLVPVVRDATGSELAPMLALAAVLLVTSL 414 >YPO1768 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 256 bits (653), Expect = 9e-68, Method: Compositional matrix adjust. Identities = 165/433 (38%), Positives = 245/433 (56%), Gaps = 11/433 (2%) Query: 19 SQAEDAIYRKVWLRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAIFYV 78 S + ++ K++ R+IPFLF+ +V +FLDRINIGFA L M +DLG S +GL +FYV Sbjct: 22 SAQQQSVINKLFRRLIPFLFLLFVFAFLDRINIGFAGLTMGKDLGLSATTFGLATTLFYV 81 Query: 79 GYVLFEVPSNMALARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRFLLGVFEAGFF 138 Y+LF +PSN+ L GARR + IMVLWG+AS + Y LR ++G+ EAGF Sbjct: 82 TYILFAIPSNIMLGIVGARRWIATIMVLWGIASTATLFAVGPNSLYLLRMIVGITEAGFL 141 Query: 139 PGIVLYLSYWFLARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAI 198 PGI++YL+YWF A RA A+F + V LG LVSG+I+ + G + + GWQW+F + Sbjct: 142 PGILVYLTYWFPAHFRARANALFMVAMPVTMALGSLVSGYILA-LDGFLNMRGWQWLFLL 200 Query: 199 EGAPAVLLGLLAIFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSGHSLAALRQAL 258 EG P+VLLG + F L D P +A+WL+ E++ LQ + + L+ + + AL Q+ Sbjct: 201 EGFPSVLLGGVVWFYLDDTPQKARWLTKEDKQCLQEMLESDRLQLAKQADY--GALPQSA 258 Query: 259 SHRTTY-----LFAFIYFALTCGSLTLNFWMPLMIRDFGIKDV-VEVSLYSVIPNAIGAV 312 R + ++ YF LT +N W P +++ F + + L + IP Sbjct: 259 MWREIFTPVVLMYTLAYFCLTNTLSAVNIWTPQILQSFNQSSSNITIGLLAAIPQVCTIA 318 Query: 313 GLILIARRSDRRNERHGHFAVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFAALPI 372 G+I +RRSDR ER H + A + +S LG++ +A+ F A+ I Sbjct: 319 GMIWWSRRSDRVQERKMHTVLPYLFAAAGWVLASATQNSVIQLLGII-MASTGSFTAMAI 377 Query: 373 FWSLPPGLLPAQTIAPGIAFISSVGITSGIVSPWLIGLVKTRTGNMDIALYILAGLLLLS 432 FW+ P + + A GIA I++ G VSP LIG +K +TGN + LY +AGLL++ Sbjct: 378 FWTTPDQSISLRARAVGIAVINATGNIGSAVSPVLIGWLKDQTGNFNSGLYFVAGLLVI- 436 Query: 433 GLAMWSLIPRKAA 445 G ++ +IP K A Sbjct: 437 GAVIFLMIPMKKA 449 >PA2214 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 440 Score = 253 bits (647), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 161/403 (39%), Positives = 228/403 (56%), Gaps = 8/403 (1%) Query: 31 LRIIPFLFICYVVSFLDRINIGFAQLQMKQDLGFSDAMYGLGAAIFYVGYVLFEVPSNMA 90 LR++PFL + YV++F+DR N+G+A+ ++ D G DA + GA+IF++GY FEVPSN+ Sbjct: 20 LRLLPFLVLMYVLAFIDRANVGYARAFLQADTGLGDAAFAFGASIFFIGYACFEVPSNLM 79 Query: 91 LARFGARRTFSRIMVLWGLASVGMMAVTDAAHFYTLRFLLGVFEAGFFPGIVLYLSYWFL 150 L R GAR RIMV WGL S MM DA FY LRFLLGV EAGFFPGI+LYL+YWF Sbjct: 80 LHRLGARVWLCRIMVTWGLVSAAMMFADDAMTFYVLRFLLGVAEAGFFPGIILYLTYWFP 139 Query: 151 ARRRAAVMAIFFAGVAVAGVLGGLVSGWIMRDMAGVMGLYGWQWMFAIEGAPAVLLGLLA 210 R RA + +F+ G+ +A VLGG +SGW++ + G+ GL WQW+F EG A L+G+ A Sbjct: 140 QRSRAQALGLFYFGLPLALVLGGPLSGWLL-EFHGIFGLANWQWLFVTEGLLASLVGIAA 198 Query: 211 IFLLADGPAQAKWLSPEERSFLQARHQQEALRTHHVSGHS-LAALRQALSHRTTYLFAFI 269 F L D P A WLS E++ L+ +E R H L+ALR + F + Sbjct: 199 YFYLVDRPRDAGWLSDEQKRALEGELAEEDTRKQARGPHGFLSALRSGQVLK----FCLV 254 Query: 270 YFALTCGSLTLNFWMPLMIRDFGIKDV-VEVSLYSVIPNAIGAVGLILIARRSDRRNERH 328 YF + + F++P I F V + V L + IP V L+ R++DR + H Sbjct: 255 YFTIQMSVYGVVFYLPTRIASFLDGQVGLNVGLITAIPWVCALVVTRLVTRQADRSGQ-H 313 Query: 329 GHFAVCTTGGALALAALTLHPSSFAVSLGLLSVAAVLIFAALPIFWSLPPGLLPAQTIAP 388 AV G A A A + + +++ AA + P+FW+LP G L A Sbjct: 314 RQLAVAMLGMAAAGIAASALAGNLGLAVIAFCFAASGFVSVQPLFWTLPTGYLSGAAAAS 373 Query: 389 GIAFISSVGITSGIVSPWLIGLVKTRTGNMDIALYILAGLLLL 431 GIA I+S+G G V+P L L++++ + ++ LA + LL Sbjct: 374 GIALINSLGNLGGFVAPNLKTLMESQFADPRAGMFALAAVGLL 416