BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0056.p (501 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Z2875 [GEPR] COG0477 Permeases of the major facilitator superfam... 320 5e-87 ECs2538 [GEPR] COG0477 Permeases of the major facilitator superf... 320 5e-87 yebQ [GEPR] COG0477 Permeases of the major facilitator superfami... 320 5e-87 YPO1712 [GEPR] COG0477 Permeases of the major facilitator superf... 316 7e-86 BMEII0280 [GEPR] COG0477 Permeases of the major facilitator supe... 312 1e-84 STM1843 [GEPR] COG0477 Permeases of the major facilitator superf... 300 4e-81 RSp1359 [GEPR] COG0477 Permeases of the major facilitator superf... 245 2e-64 RSp1328 [GEPR] COG0477 Permeases of the major facilitator superf... 245 2e-64 CAC3668 [GEPR] COG0477 Permeases of the major facilitator superf... 207 5e-53 AF2258 [GEPR] COG0477 Permeases of the major facilitator superfa... 192 2e-48 >Z2875 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 494 Score = 320 bits (820), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 186/439 (42%), Positives = 262/439 (59%), Gaps = 16/439 (3%) Query: 11 RF-LPIPAMELFSDHPNDEGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQT 69 RF +P+P ++ +GLP QR A+L ++ +MAV DG I NVALP I+ L Sbjct: 33 RFKIPMPKVQ-------ADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHA 85 Query: 70 SAAVSIWVSNAYLLATAMTLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLI 129 + A SIWV NAY +A ++L +F+ L G+R + GL VF L+SL CALS S+ +L Sbjct: 86 TPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILT 145 Query: 130 LMRILQGLGGAAMLSIAPAIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLG 189 L R++QG GGAA++S+ A+ R I+P R LGR +G+N+ +VA S+A GP + +L+ Sbjct: 146 LARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIAS 205 Query: 190 WEWIFAINVPLGVLAVWLAWNAV-PDTRKPAQAAFDLAGALWSALAMGALIMAADTCARF 248 W+W+F INVPLG++A+ LA + P+ + ++ FDL A+ +AL G LI A A Sbjct: 206 WKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFA-- 263 Query: 249 AEPGQGSEAAFTAAAYAVTALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASF 308 QG AA V ++ G+ F+R Q PLLP+D+ P FSL+ TS+ SF Sbjct: 264 ----QGQSLTLIAAELVVM-VVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSF 318 Query: 309 VGQGIAFVALPFLFQNAYGYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGL 368 Q +A V+LPF Q G + E+ L TPWPL +++AP AG L +R LL +LGL Sbjct: 319 CAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGL 378 Query: 369 ALFALGLVLLALLPDQAQPWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVL 428 + A GL L LLP +I W ++CG GFG FQSPNN ++ + RERSG ASG+L Sbjct: 379 FIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGML 438 Query: 429 AIMRTFGQCLGAALLGVIL 447 R GQ GAAL+ ++L Sbjct: 439 GTARLLGQSSGAALVALML 457 >ECs2538 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 494 Score = 320 bits (820), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 186/439 (42%), Positives = 262/439 (59%), Gaps = 16/439 (3%) Query: 11 RF-LPIPAMELFSDHPNDEGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQT 69 RF +P+P ++ +GLP QR A+L ++ +MAV DG I NVALP I+ L Sbjct: 33 RFKIPMPKVQ-------ADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHA 85 Query: 70 SAAVSIWVSNAYLLATAMTLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLI 129 + A SIWV NAY +A ++L +F+ L G+R + GL VF L+SL CALS S+ +L Sbjct: 86 TPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQILT 145 Query: 130 LMRILQGLGGAAMLSIAPAIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLG 189 L R++QG GGAA++S+ A+ R I+P R LGR +G+N+ +VA S+A GP + +L+ Sbjct: 146 LARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIAS 205 Query: 190 WEWIFAINVPLGVLAVWLAWNAV-PDTRKPAQAAFDLAGALWSALAMGALIMAADTCARF 248 W+W+F INVPLG++A+ LA + P+ + ++ FDL A+ +AL G LI A A Sbjct: 206 WKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFA-- 263 Query: 249 AEPGQGSEAAFTAAAYAVTALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASF 308 QG AA V ++ G+ F+R Q PLLP+D+ P FSL+ TS+ SF Sbjct: 264 ----QGQSLTLIAAELVVM-VVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSF 318 Query: 309 VGQGIAFVALPFLFQNAYGYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGL 368 Q +A V+LPF Q G + E+ L TPWPL +++AP AG L +R LL +LGL Sbjct: 319 CAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGL 378 Query: 369 ALFALGLVLLALLPDQAQPWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVL 428 + A GL L LLP +I W ++CG GFG FQSPNN ++ + RERSG ASG+L Sbjct: 379 FIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGML 438 Query: 429 AIMRTFGQCLGAALLGVIL 447 R GQ GAAL+ ++L Sbjct: 439 GTARLLGQSSGAALVALML 457 >yebQ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 494 Score = 320 bits (820), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 184/436 (42%), Positives = 260/436 (59%), Gaps = 15/436 (3%) Query: 13 LPIPAMELFSDHPNDEGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAA 72 +P+P ++ +GLP QR A+L ++ +MAV DG I NVALP I+ L + A Sbjct: 36 IPMPKVQ-------ADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPA 88 Query: 73 VSIWVSNAYLLATAMTLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMR 132 SIWV NAY +A ++L +F+ L G+R + GL VF L+SL CALS S+ +L L R Sbjct: 89 SSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSDSLQMLTLAR 148 Query: 133 ILQGLGGAAMLSIAPAIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEW 192 ++QG GGAA++S+ A+ R I+P R LGR +G+N+ +VA S+A GP + +L+ W+W Sbjct: 149 VIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIAAAILSIASWKW 208 Query: 193 IFAINVPLGVLAVWLAWNAV-PDTRKPAQAAFDLAGALWSALAMGALIMAADTCARFAEP 251 +F INVPLG++A+ LA + P+ + ++ FDL A+ +AL G LI A A Sbjct: 209 LFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFA----- 263 Query: 252 GQGSEAAFTAAAYAVTALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQ 311 QG AA V ++ G+ F+R Q PLLP+D+ P FSL+ TS+ SF Q Sbjct: 264 -QGQSLTLIAAELVVM-VVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQ 321 Query: 312 GIAFVALPFLFQNAYGYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALF 371 +A V+LPF Q G + E+ L TPWPL +++AP AG L +R LL +LGL + Sbjct: 322 MLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAGLLGALGLFIM 381 Query: 372 ALGLVLLALLPDQAQPWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIM 431 A GL L LLP +I W ++CG GFG FQSPNN ++ + RERSG ASG+L Sbjct: 382 AAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTA 441 Query: 432 RTFGQCLGAALLGVIL 447 R GQ GAAL+ ++L Sbjct: 442 RLLGQSSGAALVALML 457 >YPO1712 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 455 Score = 316 bits (810), Expect = 7e-86, Method: Compositional matrix adjust. Identities = 182/423 (43%), Positives = 250/423 (59%), Gaps = 8/423 (1%) Query: 26 NDEGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLAT 85 +GLP QR A+L + MAV DGTI NVALP I++ L TS A SIWV NAY LA Sbjct: 5 TSDGLPVPQRYAAILVIALGIMMAVLDGTIANVALPTIARDLNTSPATSIWVVNAYQLAI 64 Query: 86 AMTLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSI 145 ++L + A+L IG+R + AGL +F++ SL CALS S+ L R+LQG G AA++S+ Sbjct: 65 TISLLSMASLGDIIGYRRVYQAGLLIFSVTSLFCALSDSLWTLTFARVLQGFGAAALMSV 124 Query: 146 APAIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAV 205 A+ R I+P LGR +G+N ++VA S+A GP + +L+ W+W+FA+NVP+G+LA Sbjct: 125 NTALIRIIYPRAQLGRGIGINTLIVAVSSAAGPSIAAAVLSVASWQWLFALNVPIGLLAW 184 Query: 206 WLAWNAVP-DTRKPAQAAFDLAGALWSALAMGALIMAADTCARFAEPGQGSEAAFTAAAY 264 L +P + K FD+ + +AL G LI A ++ P AA Sbjct: 185 CLGIKFLPANNTKSNGNRFDITSCVLNALTFGLLITAISGFSQGQSPA-------VIAAQ 237 Query: 265 AVTALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFLFQN 324 V LL G FVR Q + PLLP+D+ P F+L+ TS+ SF Q +A V+LPF Q Sbjct: 238 VVALLLIGFFFVRRQLTQSFPLLPVDLLRIPIFALSIGTSIFSFAAQMLAMVSLPFFLQT 297 Query: 325 AYGYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALLPDQ 384 G + L TPWPL +++AP AGRL +R+ LL +GLA+FA GL LLA+LP Sbjct: 298 VLGRDEVATGLLLTPWPLATMVIAPIAGRLVERYHAGLLGGIGLAVFASGLFLLAVLPAN 357 Query: 385 AQPWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLG 444 DI WR ++CG GFG FQ+PNN ++ + RSG ASG+L R GQ GAAL+ Sbjct: 358 PSDVDIIWRMILCGAGFGLFQTPNNHTIISAAPQHRSGGASGMLGTARLLGQTSGAALVA 417 Query: 445 VIL 447 ++ Sbjct: 418 LMF 420 >BMEII0280 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 463 Score = 312 bits (799), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 194/468 (41%), Positives = 273/468 (58%), Gaps = 24/468 (5%) Query: 28 EGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLATAM 87 +GLP + A +M T+AV DGTI NVALP I+ A SIW+ N Y LA + Sbjct: 20 DGLPRPRIYWAWATLMVGLTLAVIDGTIANVALPTIAADFSAGPAASIWIVNGYQLAIVI 79 Query: 88 TLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSIAP 147 T+ AAL G+R + AG+A+FT+AS+GC S S+ L L RI+QGLG A ++S+ Sbjct: 80 TMLPLAALGEIYGYRRVYVAGVALFTIASIGCVFSRSLEALTLARIIQGLGAAGLMSVNT 139 Query: 148 AIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAVWL 207 A+ R P G +GLNA+ VA S+ +GP L G +L++L W W+F IN+PLG+ AV + Sbjct: 140 ALLRYTVPQAKFGTAIGLNALFVAVSSTIGPSLAGVMLSSLSWPWLFVINIPLGIAAVLM 199 Query: 208 AWNAVPDTRKPAQAAFDLAGALWSALAMGALIMAADTCARFAEPGQGSEAAFTAAAYAVT 267 ++PD + A+ FD+ A+ A+ G LI D+ A GS A A + Sbjct: 200 GLRSLPDNDRSARK-FDVVSAILCAVTFGLLITTIDS----AGNKIGSLAVMLQA---LC 251 Query: 268 ALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFLFQNAYG 327 LLAG+ R +DPLLPLD+ P F+L+ TS+ SF+ Q +AF++LPFLFQ +G Sbjct: 252 CLLAGIWLTRRSFHMSDPLLPLDLLRIPVFTLSICTSIMSFLAQMMAFISLPFLFQTVFG 311 Query: 328 YTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALLPDQAQP 387 + E L PWP+ + LVAP +G+L+D++SPA+L LGL F++GL L+ LLP Sbjct: 312 FRPIEVGFLMMPWPIALALVAPLSGKLSDKYSPAILGLLGLITFSVGLALVGLLPGHPTI 371 Query: 388 WDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLGVIL 447 DI WR +CG+GFG FQ+PNNR M+ + R RSG ASG+L R GQ +GAAL+ +L Sbjct: 372 PDICWRMAICGIGFGLFQAPNNRMMITSTPRARSGAASGMLGTARLLGQSVGAALVAFLL 431 Query: 448 AVRTAAAVAQGELQMNPVQDGEAIRIALWLAAAATALATAVSASRLRR 495 +Q ++ P L+LA+ A+ +S SRLR Sbjct: 432 --------SQWGVEGTPY--------ILFLASGFALFASVISISRLRH 463 >STM1843 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 457 Score = 300 bits (769), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 178/421 (42%), Positives = 246/421 (58%), Gaps = 8/421 (1%) Query: 28 EGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLATAM 87 +GLP QR A+L ++ +MAV DG I NVALP I+ L S A SIW+ NAY +A + Sbjct: 7 DGLPLPQRYGAILTIIIGISMAVLDGAIANVALPTIATDLHASPASSIWIVNAYQIAIVV 66 Query: 88 TLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSIAP 147 +L + + L G+ + GL VF L+SL CALS S+ +L L RI QG GGAA++S+ Sbjct: 67 SLLSLSFLGDMFGYHRIYKCGLVVFLLSSLFCALSDSLQMLTLARIAQGFGGAALMSVNT 126 Query: 148 AIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAVWL 207 A+ R I+P R LGR +G+N+ +VA S+A GP + +L+ W+W+F INVPLG++A+ L Sbjct: 127 ALIRLIYPQRHLGRGMGINSFIVAVSSAAGPTIAAAILSISSWKWLFLINVPLGIIALIL 186 Query: 208 AWNAVP-DTRKPAQAAFDLAGALWSALAMGALIMAADTCARFAEPGQGSEAAFTAAAYAV 266 A +P + + FDL A+ +AL G LI A A QG A V Sbjct: 187 AIRFLPANIAHDTKPRFDLPSAVMNALTFGLLITALSGFA------QGQSLTLIGAELLV 240 Query: 267 TALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFLFQNAY 326 ++ FVR Q PLLP+D+ P FSL+ TS+ SF Q +A V+LPF Q Sbjct: 241 LVVVG-FFFVRRQLSLPVPLLPIDLLRIPLFSLSIGTSICSFCAQMLAMVSLPFYLQTVL 299 Query: 327 GYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALLPDQAQ 386 G + E+ L TPWPL +++AP AG L +R LL +LG+ + A GL L +LP Sbjct: 300 GRSEVETGLLLTPWPLATMVMAPLAGYLIERLHAGLLGALGMVIMAAGLFALVMLPASPS 359 Query: 387 PWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLGVI 446 +I W ++CG GFG FQSPNN ++ + RERSG ASG+L R GQ GAAL+ ++ Sbjct: 360 DLNIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGMLGTARLLGQSTGAALVALM 419 Query: 447 L 447 L Sbjct: 420 L 420 >RSp1359 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 479 Score = 245 bits (625), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 151/422 (35%), Positives = 225/422 (53%), Gaps = 16/422 (3%) Query: 26 NDEGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLAT 85 + L +RR M A+MTA +A D TI N ALP+I+ L +S A IWV+NAY +A Sbjct: 25 QEVTLSTARRRMCMAALMTAAILAALDTTIANTALPEIAVDLHSSEATIIWVTNAYQIAM 84 Query: 86 AMTLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSI 145 L FAAL IG+R F GL +F +AS C S ++ LL++ R +QG+G AA++S+ Sbjct: 85 IAALLPFAALGESIGYRRVFIGGLTLFGIASAICGSSSTLALLVVGRAMQGVGAAAIMSV 144 Query: 146 APAIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAV 205 A R I P ++LGR L +A++VA +GPV+ T+L W W+F +NVP+ A+ Sbjct: 145 IAAFIRHIHPPKMLGRGLSTHALVVAIGFTLGPVVASTILTVASWHWLFGVNVPVAAAAI 204 Query: 206 WLAWNAVPDT----RKPAQAAFDLAGALWSALAMGALIMAADTCARFAEPGQGSEAAFTA 261 L+ +PD + + L A + L G +M + + A Sbjct: 205 VLSVLYLPDVAGGRHRFESTSAALCTAFFGLLMFGICLM------------ENEGGSVVA 252 Query: 262 AAYAVTALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFL 321 +++L + +R QR P+L +D+ A L++LTS+ +F Q +A V+LPFL Sbjct: 253 VLCTLSSLACAIGLMRKQRGHPAPMLAVDLMAIRTVRLSSLTSICAFATQSLALVSLPFL 312 Query: 322 FQNAYGYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALL 381 Q +G + + WPL + ++A L+DR+ LL S+GL + LG+V LA + Sbjct: 313 LQGTFGMPVARTGFVIAAWPLLVAVMAVAVAPLSDRYPSGLLCSVGLIVLTLGMVSLATM 372 Query: 382 PDQAQPWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAA 441 I R VCG+GFG FQSPN RE++ + RSG AS ++AI R GQ GA Sbjct: 373 SGSVSSMTIAVRLAVCGIGFGLFQSPNMREIMSGATAVRSGGASAIVAISRLIGQTFGAG 432 Query: 442 LL 443 L+ Sbjct: 433 LV 434 >RSp1328 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 479 Score = 245 bits (625), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 151/422 (35%), Positives = 225/422 (53%), Gaps = 16/422 (3%) Query: 26 NDEGLPGKQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLAT 85 + L +RR M A+MTA +A D TI N ALP+I+ L +S A IWV+NAY +A Sbjct: 25 QEVTLSTARRRMCMAALMTAAILAALDTTIANTALPEIAVDLHSSEATIIWVTNAYQIAM 84 Query: 86 AMTLAAFAALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSI 145 L FAAL IG+R F GL +F +AS C S ++ LL++ R +QG+G AA++S+ Sbjct: 85 IAALLPFAALGESIGYRRVFIGGLTLFGIASAICGSSSTLALLVVGRAMQGVGAAAIMSV 144 Query: 146 APAIHRTIFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAV 205 A R I P ++LGR L +A++VA +GPV+ T+L W W+F +NVP+ A+ Sbjct: 145 IAAFIRHIHPPKMLGRGLSTHALVVAIGFTLGPVVASTILTVASWHWLFGVNVPVAAAAI 204 Query: 206 WLAWNAVPDT----RKPAQAAFDLAGALWSALAMGALIMAADTCARFAEPGQGSEAAFTA 261 L+ +PD + + L A + L G +M + + A Sbjct: 205 VLSVLYLPDVAGGRHRFESTSAALCTAFFGLLMFGICLM------------ENEGGSVVA 252 Query: 262 AAYAVTALLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFL 321 +++L + +R QR P+L +D+ A L++LTS+ +F Q +A V+LPFL Sbjct: 253 VLCTLSSLACAIGLMRKQRGHPAPMLAVDLMAIRTVRLSSLTSICAFATQSLALVSLPFL 312 Query: 322 FQNAYGYTAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALL 381 Q +G + + WPL + ++A L+DR+ LL S+GL + LG+V LA + Sbjct: 313 LQGTFGMPVARTGFVIAAWPLLVAVMAVAVAPLSDRYPSGLLCSVGLIVLTLGMVSLATM 372 Query: 382 PDQAQPWDIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAA 441 I R VCG+GFG FQSPN RE++ + RSG AS ++AI R GQ GA Sbjct: 373 SGSVSSMTIAVRLAVCGIGFGLFQSPNMREIMSGATAVRSGGASAIVAISRLIGQTFGAG 432 Query: 442 LL 443 L+ Sbjct: 433 LV 434 >CAC3668 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 486 Score = 207 bits (527), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 136/453 (30%), Positives = 226/453 (49%), Gaps = 14/453 (3%) Query: 33 KQRRRAMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLATAMTLAAF 92 K+R ++ V++AT MA DG+I+NVALP ++ L S A WV ++L+ A T+ F Sbjct: 10 KKRWIILITVLSATLMATLDGSIVNVALPNMTLKLHVSGASIQWVVTSFLITVAATILIF 69 Query: 93 AALSSRIGFRAQFSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSIAPAIHRT 152 L IG F G+ +FTL SL C + S+ +L++ R++Q +G AA ++ I Sbjct: 70 GRLGDIIGKTKVFKFGVILFTLGSLLCGFTSSLVVLVVARVIQAIGAAATMATNQGIITQ 129 Query: 153 IFPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAVWLAWNAV 212 FP GR LGL VA +GP LGG +++ WE+IF IN+P+G++ L Sbjct: 130 TFPPNERGRALGLLGTFVALGAMIGPPLGGLIISLASWEYIFLINIPIGIVVFILCIKVF 189 Query: 213 PDTRKPAQAAFDLAGA----LWSALAMGALIMAADTCARFAEPGQGSEAAFTAAAYAVTA 268 P T D GA +++ L GAL+ G + A+ V + Sbjct: 190 PKTNDKLDEKLDTTGAVLFTVFTVLLFGALVQGETV---------GYSNIYIILAFIV-S 239 Query: 269 LLAGLAFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFLFQNAYGY 328 LA AF+ + + PLL L IF+N FS++ + + SF + + LPF FQ+ + Sbjct: 240 FLALAAFLIIEIKKKQPLLDLSIFSNSLFSVSVICAFTSFTAISASNIILPFYFQDTLKF 299 Query: 329 TAFESAALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALLPDQAQPW 388 +A + P+ + +VAP +G L+D+ +L+ +GL L ++GL L++ L + Sbjct: 300 SAAMTGIFMVVSPVVLSIVAPFSGYLSDKIGSEILTLIGLFLTSVGLFLISTLTAASPVA 359 Query: 389 DIGWRALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLGVILA 448 + ++ +G G FQ+PNN ++ V R + G A V A++R G +G + ++L Sbjct: 360 LLMTYIVIMTIGNGMFQAPNNSLVMSTVPRNKLGIAGSVNALIRNLGFVVGTSFATLLLY 419 Query: 449 VRTAAAVAQGELQMNPVQDGEAIRIALWLAAAA 481 R ++ + + +D + W+ AA Sbjct: 420 NRMSSKMGHRVVDYIKGRDDVFMYGMKWVYIAA 452 >AF2258 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 503 Score = 192 bits (487), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 130/419 (31%), Positives = 205/419 (48%), Gaps = 14/419 (3%) Query: 38 AMLAVMTATTMAVFDGTIINVALPQISQALQTSAAVSIWVSNAYLLATAMTLAAFAALSS 97 A L V M + D +++NVALP+I++ + W+ NAY L T+ L+ Sbjct: 14 AFLPVSAGLFMVLLDVSVLNVALPRIAEDFGAKMSDLQWIMNAYTL----TMVVLLVLAG 69 Query: 98 RIGFRAQ----FSAGLAVFTLASLGCALSGSVTLLILMRILQGLGGAAMLSIAPAIHRTI 153 RIG + F G+ +F L S CA S + +I R LQ +GG + AI + Sbjct: 70 RIGDMVRRDRFFILGMVIFVLGSFLCAQSWNTQSMIAFRTLQAIGGTILSGNVLAIAAEL 129 Query: 154 FPNRLLGRILGLNAVLVAASTAVGPVLGGTLLATLGWEWIFAINVPLGVLAVWLAWNAVP 213 FP G ++GLNA+L A+S +GP++GG L L W W+F IN+P+G++A+ AW +P Sbjct: 130 FPPGRRGEVMGLNAILTASSFTLGPIIGGWLTTHLSWHWVFYINIPIGIVAIAAAWFTLP 189 Query: 214 DTRKPAQAAFDLAGALWSALAMGALIMAADTCARFAEPGQGSEAAFTAAAYAVTALLAGL 273 + D GA+ ++ +GAL + + + + + F + AL L Sbjct: 190 PLGGREKVPIDWVGAVLLSIGLGALTLGIIEGQNWGWWDEKTLSCF------IIALPYLL 243 Query: 274 AFVRGQRRAADPLLPLDIFANPRFSLAALTSLASFVGQGIAFVALPFLFQNAYGYTAFES 333 AF + R P+L L +F FS+ + + F G + P+ Q +A E+ Sbjct: 244 AFSLWELRTPYPMLDLSLFKIRNFSVGVVATAILFFGVSASLFVFPYFLQGLKFLSAEEA 303 Query: 334 AALFTPWPLGIVLVAPHAGRLADRHSPALLSSLGLALFALGLVLLALLPDQAQPWDIGWR 393 P+ VAP AGRL+DR +P L SLG FA+GL+ + + + WD + Sbjct: 304 GYWLVAIPIMNTFVAPVAGRLSDRMNPKYLMSLGPLFFAIGLINITSIDVDIKYWDFFAK 363 Query: 394 ALVCGMGFGFFQSPNNREMLGNVSRERSGNASGVLAIMRTFGQCLGAALLGVILAVRTA 452 G+G G SP+ +L +V E+ G A+G + + T GQ +G A+ GV+L R + Sbjct: 364 IAPMGIGMGMLMSPSFNVILSSVPLEKVGMANGTVRSVNTLGQAMGIAVGGVLLTTRMS 422