BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0011.0002.p (1048 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0010 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1602 0.0 SMc02867 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizob... 1360 0.0 AGl3217 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteri... 1288 0.0 STM0475 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1222 0.0 acrB [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1209 0.0 ZacrB [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1208 0.0 ECs0515 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1208 0.0 STM3391 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella ... 1207 0.0 CC0807 [V] COG0841 Cation/multidrug efflux pump Ccr Caulobacter ... 1193 0.0 YPO3133 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1192 0.0 >RSc0010 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1049 Score = 1602 bits (4147), Expect = 0.0, Method: Compositional matrix adjust. Identities = 789/1044 (75%), Positives = 906/1044 (86%), Gaps = 2/1044 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M KFFIDRPVFAWVLA+FI++AGA++IT LP++QYP IAPP+I++TATYPGA+A+TLDD+ Sbjct: 1 MAKFFIDRPVFAWVLALFIIVAGAISITQLPIAQYPTIAPPSIIITATYPGASAKTLDDA 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQA-NGQVQITITFSPETNPDLAAVDVQNRLKRVEARLP 119 VTS+IEQEMNGADGL YIES SQA NGQ IT+TF P T+P LA VDVQNRLKRVEARLP Sbjct: 61 VTSIIEQEMNGADGLLYIESVSQAGNGQATITVTFKPGTDPALAQVDVQNRLKRVEARLP 120 Query: 120 AAVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFG 179 ++VTQQGVQV K+RSNFLLF L S DGK+DPVALGDY+SRNVLNE+KRVPGVGQA LFG Sbjct: 121 SSVTQQGVQVDKTRSNFLLFATLISKDGKMDPVALGDYISRNVLNEVKRVPGVGQAVLFG 180 Query: 180 TERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQ 239 TERAMRIWIDP KL+G LTP DV AI+ QNALV+ GTLG LPS Q IAATVVV GQ Sbjct: 181 TERAMRIWIDPAKLVGYKLTPTDVYNAIRNQNALVSAGTLGDLPSTSDQPIAATVVVEGQ 240 Query: 240 LTSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANA 299 +T+ EQFGNI+L + +G+ VR++DVAR+E+GGQ+Y TS R++G+P S IGVQLSPT NA Sbjct: 241 MTTTEQFGNIVLVSKPDGSQVRIKDVARLELGGQTYATSARINGQPISAIGVQLSPTGNA 300 Query: 300 LGTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFL 359 LGTA AV K++EL+KYFP GV+Y IPYDTSKFV+ISIEEVVKTL EA+ LVFLVM +FL Sbjct: 301 LGTAKAVKAKLDELSKYFPAGVEYKIPYDTSKFVQISIEEVVKTLFEAMALVFLVMLVFL 360 Query: 360 QNIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERI 419 QNIRYT+IP+IVVP++LLG FAT+ GFSINVLTMFG+VLAIGILVDDAIVVVENVERI Sbjct: 361 QNIRYTLIPSIVVPISLLGAFATMNALGFSINVLTMFGLVLAIGILVDDAIVVVENVERI 420 Query: 420 MSEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMV 479 MS+EGL P +ATRKAMGQI+GA+IGITLVL+AVFIPMAFF G+VGAIYRQFSLSMVAS+ Sbjct: 421 MSQEGLPPREATRKAMGQITGAIIGITLVLMAVFIPMAFFSGSVGAIYRQFSLSMVASIF 480 Query: 480 FSVLMAFTLTPALCATILKPVEKGHHHEKKGFFGWFNRKFNSTASGYQGIIGGMLNKAGR 539 FS LMA TLTPALC+T+LKP+EKG HHEKKGFFGWFNR F ST YQ ++ +L K R Sbjct: 481 FSALMALTLTPALCSTLLKPIEKGSHHEKKGFFGWFNRMFTSTTDRYQSLVERVLKKTFR 540 Query: 540 YMIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYLK 599 YM++Y ++A V L++RLP+SFLPNEDQGYIITN+QLPP AS +RT V+K +E YY Sbjct: 541 YMVIYGALIAAVVFLFMRLPSSFLPNEDQGYIITNIQLPPAASANRTLEVIKHVENYYQH 600 Query: 600 DPAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQRDKSQSADAIAGKAFGA-FSQIKDAI 658 + AVE+ +AV G+SFSGNG NAALVFT LKDWS R QSADA+AG+AFGA F I+DAI Sbjct: 601 EKAVENIVAVQGFSFSGNGPNAALVFTTLKDWSSRGADQSADAVAGRAFGALFGGIRDAI 660 Query: 659 VFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQSKVLAGVRPEGLED 718 VFPLNPPPIPELGNATGFTFRLQDR GLGH AL+ ARNQ+LGMA QSKVL VRP+GLED Sbjct: 661 VFPLNPPPIPELGNATGFTFRLQDRGGLGHDALMAARNQLLGMAGQSKVLKNVRPDGLED 720 Query: 719 APQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRRLQP 778 +PQ Q+DIDR+KANALGV F+ IN+VLSTALGS+Y NDFPN GRQQRVIVQAD R+QP Sbjct: 721 SPQYQVDIDREKANALGVAFADINNVLSTALGSAYANDFPNYGRQQRVIVQADRINRMQP 780 Query: 779 EDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEAMAE 838 ED+ NLY RN+ G+MVP SAF W+ GPVQL+RYNGYP+++I+G AA G STG+AM E Sbjct: 781 EDIMNLYVRNTQGSMVPMSAFAKGHWVVGPVQLVRYNGYPSVRISGDAATGASTGDAMDE 840 Query: 839 MESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLAVML 898 ME ++LP G GFEWTGQSL+EK+SG+QAPALYALSL+AVFLVLAALYES SIP AV+L Sbjct: 841 MEHLASRLPAGIGFEWTGQSLQEKSSGSQAPALYALSLLAVFLVLAALYESWSIPAAVIL 900 Query: 899 VVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDLQAQGKGLIEAT 958 VVPLG+LGALLGVTLR MP+DVYFKVG+IAVVGLSAKNAILIIEFAKDLQAQGKGLIEAT Sbjct: 901 VVPLGVLGALLGVTLRFMPDDVYFKVGLIAVVGLSAKNAILIIEFAKDLQAQGKGLIEAT 960 Query: 959 LEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAVFLVPI 1018 LEAVHLRFRPIIMTS AFILGVLPLAIA+GA SASQRAIGTGVMGGMITATVLAV LVP+ Sbjct: 961 LEAVHLRFRPIIMTSFAFILGVLPLAIATGASSASQRAIGTGVMGGMITATVLAVVLVPV 1020 Query: 1019 FFVVVRKIFKGSERQRKFDAEHSP 1042 FFVVVR+IFKGSERQR+ DA H P Sbjct: 1021 FFVVVRRIFKGSERQRRLDAAHLP 1044 >SMc02867 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1048 Score = 1360 bits (3519), Expect = 0.0, Method: Compositional matrix adjust. Identities = 675/1034 (65%), Positives = 841/1034 (81%), Gaps = 3/1034 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M FFIDRP+FAWV+AIFIM+AG +AI LPVSQYP++APP I + YPGA++Q S Sbjct: 1 MPSFFIDRPIFAWVVAIFIMIAGIIAIPLLPVSQYPDVAPPQISINTNYPGASSQDTYQS 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT LIE E+NG +GL Y ES + ++G V I TF P T+P A+VD+QNR++RVE RLP Sbjct: 61 VTRLIEDELNGVEGLLYFESSTSSSGSVSIDATFQPGTDPSQASVDIQNRVQRVEPRLPD 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQGVQV ++ + FLL I L+STDG +D + LGDYLSRNVL+EI+RVPGVG+AQLF T Sbjct: 121 PVRQQGVQVDEAGAGFLLIISLTSTDGSMDAIGLGDYLSRNVLSEIQRVPGVGRAQLFAT 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 ER+MR+W+DP+K++GLNLT ADVTAAIQAQNA +A G++GA P+P TQQ+ A VV+ GQL Sbjct: 181 ERSMRVWLDPDKMLGLNLTAADVTAAIQAQNAQIASGSIGAQPNPITQQVTAPVVIKGQL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 +SPE+FG I+LRANA+G+ VRLRDVAR+E+GG+SY S RL+G PS+ I VQLSP+ NA+ Sbjct: 241 SSPEEFGAIVLRANADGSAVRLRDVARLEIGGESYTFSTRLNGSPSAAIAVQLSPSGNAM 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 T+ A+ +M+ELA++FP G++Y+IPYDTS FV +SIE+V+ TL+EA+ LVFLVMFLFLQ Sbjct: 301 STSAAIKARMDELAEFFPEGLEYSIPYDTSPFVAVSIEKVLHTLVEAVGLVFLVMFLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 N+RYTIIPTIVVPVALLGT A +L GFSINVLTMFGMVLAIGILVDDAI+VVENVERIM Sbjct: 361 NVRYTIIPTIVVPVALLGTCAVMLAMGFSINVLTMFGMVLAIGILVDDAIIVVENVERIM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 SEEGL+P DATRKAM QI+GA+IGITLVL +VFIPMAFF GAVG IYRQFSL+MV S++F Sbjct: 421 SEEGLTPKDATRKAMKQITGAVIGITLVLASVFIPMAFFPGAVGVIYRQFSLTMVVSILF 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHEKKGFFGWFNRKFNSTASGYQGIIGGMLNKAGRY 540 S L+A +LTPALCA+ LK V KGHHH K+GFFGWFNR F+ T+ GY +GG++ + GR+ Sbjct: 481 SALLALSLTPALCASFLKQVPKGHHHAKRGFFGWFNRGFDRTSHGYTRAVGGIVRRTGRF 540 Query: 541 MIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYLKD 600 M++Y+ ++A +G +++LP+SFLP+EDQG++I +QLP A+ +RTT V++Q E + ++ Sbjct: 541 MVIYLALLAGLGWAFLQLPSSFLPDEDQGFVIVMMQLPSEATANRTTEVIEQTETIFGQE 600 Query: 601 PAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQRDKSQSADAIAGKAFGAFSQIKDAIVF 660 AV+ +A+ G+SF G+GQNA L F LKDWS+RD SA +IAG+A A SQIKDAI F Sbjct: 601 KAVDTIVAINGFSFFGSGQNAGLAFVTLKDWSERDADNSAQSIAGRATMAMSQIKDAISF 660 Query: 661 PLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQSKVLAGVRPEGLEDAP 720 L+PP I LG GF+FRLQDRAGLG AL +AR+Q+L +ASQSKVL GVR EG+ DA Sbjct: 661 ALSPPAIQGLGTTGGFSFRLQDRAGLGQAALAEARDQLLDLASQSKVLTGVRFEGMPDAA 720 Query: 721 QLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRRLQPED 780 Q+ ++IDR+KAN GV F+ INS +ST LGSSYVNDFPN GR QRV VQAD +R+Q D Sbjct: 721 QVSVNIDREKANTFGVTFADINSTISTNLGSSYVNDFPNAGRMQRVTVQADETKRMQTAD 780 Query: 781 LTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEAMAEME 840 L NL RNS+G MVP SAF +W+ P Q + YNGYPA++I+G AAPG S+G+A+AEME Sbjct: 781 LLNLNVRNSNGGMVPLSAFADVEWVKAPTQTVGYNGYPAVRISGEAAPGYSSGDAIAEME 840 Query: 841 SFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLAVMLVV 900 VA+LP GFG+EWTGQSL+E SG+QAP L ALS + VFL LAALYES SIP++V++VV Sbjct: 841 RLVAELPAGFGYEWTGQSLQEIQSGSQAPLLIALSCLLVFLCLAALYESWSIPVSVIMVV 900 Query: 901 PLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDLQAQGKGLIEATLE 960 PLG++GA+L VT+R MPNDVYFKVG+IA++GLSAKNAILIIEFAK+L+ QGK LI++TLE Sbjct: 901 PLGVIGAVLAVTMRDMPNDVYFKVGLIAIIGLSAKNAILIIEFAKELREQGKSLIDSTLE 960 Query: 961 AVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAVFLVPIFF 1020 A HLRFRPI+MTSLAF LGVLPLAIA+GA S SQRAIGTGVMGGMI+ATVLA+F VP+FF Sbjct: 961 AAHLRFRPILMTSLAFTLGVLPLAIATGASSGSQRAIGTGVMGGMISATVLAIFFVPVFF 1020 Query: 1021 VVVRKIFKGSERQR 1034 V V KIF ER R Sbjct: 1021 VFVMKIF---ERGR 1031 >AGl3217 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1044 Score = 1288 bits (3333), Expect = 0.0, Method: Compositional matrix adjust. Identities = 644/1013 (63%), Positives = 817/1013 (80%), Gaps = 1/1013 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M +FFIDRP+FAWV+AIFIMLAG LAI LP++QYPN+APP I + YPGA+ + + S Sbjct: 1 MARFFIDRPIFAWVVAIFIMLAGLLAIPMLPIAQYPNVAPPQISIGTNYPGASPEDIYQS 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT IE+E+NG GL Y ES S+++G++ I +TF P TN A V+VQNR+ RVE RLP Sbjct: 61 VTRPIEEELNGVPGLIYFESTSESSGRISINVTFEPGTNIGEAQVEVQNRIARVEPRLPR 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 +VTQQG++V ++ ++FL+ + L+S DG D + LGDYLSRNVL E++RVPGVG AQLF T Sbjct: 121 SVTQQGLRVEQAGTSFLMMVALTSVDGNTDAIGLGDYLSRNVLGELRRVPGVGSAQLFAT 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 +R+MRIW+DP+K++GL+LT DV AIQAQN+ VA G +GA P+P QQI+ATV V GQL Sbjct: 181 QRSMRIWMDPDKMLGLSLTSDDVINAIQAQNSQVAAGRIGASPNPVGQQISATVNVQGQL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 TSPE+FG+I+LRAN +G++VRLRDVARVEVGG+SY+ S RL+GKPS+ IGVQLSPTANA+ Sbjct: 241 TSPEEFGSIVLRANPDGSSVRLRDVARVEVGGESYNFSSRLNGKPSAAIGVQLSPTANAM 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 T+ V MEEL++YFP G++Y IPYDTS FVKISIE+V+ TLIEA++LVF+VMF+FLQ Sbjct: 301 QTSEGVRATMEELSRYFPQGIEYEIPYDTSPFVKISIEKVIHTLIEAMILVFVVMFVFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 NIRYTIIPT+VVPVALLGT A + + GFSINVLTMF MVLAIGILVDDAIVVVENVERIM Sbjct: 361 NIRYTIIPTLVVPVALLGTCAVMYVSGFSINVLTMFAMVLAIGILVDDAIVVVENVERIM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 +EE LSP +ATRKAMGQISGA+IGITLVL AVF+PMAFF GAVG IY+QFSL+MV S++F Sbjct: 421 AEEHLSPKEATRKAMGQISGAIIGITLVLTAVFVPMAFFPGAVGIIYQQFSLTMVVSILF 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHEKKGFFGWFNRKFNSTASGYQGIIGGMLNKAGRY 540 S +A +LTPALCA+ LKP++ G HHEKKGFFGWFNR F+ + Y +GG++ ++GR+ Sbjct: 481 SGFLALSLTPALCASFLKPIKAG-HHEKKGFFGWFNRNFDKASHKYSSSVGGIIKRSGRF 539 Query: 541 MIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYLKD 600 MI+Y ++A +G Y++LP+SFLPNEDQGY+I ++Q P AST RT ++QIE+ ++++ Sbjct: 540 MIIYAALLAGLGWAYMQLPSSFLPNEDQGYLIVDIQAPAEASTERTLQSIQQIEKIFMEE 599 Query: 601 PAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQRDKSQSADAIAGKAFGAFSQIKDAIVF 660 PAVE IA+ G+SFSG+GQNA L F LKDWS+R SA AI+ + G + DA+ F Sbjct: 600 PAVERVIAISGFSFSGSGQNAGLAFATLKDWSERGPEDSAAAISARINGKLWGLPDAMSF 659 Query: 661 PLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQSKVLAGVRPEGLEDAP 720 L+PPPI LGN++GFTFRLQDR+G G TAL A Q++ A QS VLAG+R EG+ DA Sbjct: 660 ALSPPPIQGLGNSSGFTFRLQDRSGAGQTALSAAGAQLMAAARQSPVLAGLRIEGMPDAA 719 Query: 721 QLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRRLQPED 780 Q+ L IDR+KAN GV FS IN+ +S +GSSYVNDFPN GR QRV VQA+ +R++ ED Sbjct: 720 QVNLIIDREKANTFGVTFSDINATISANMGSSYVNDFPNAGRMQRVTVQAEQGQRMKTED 779 Query: 781 LTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEAMAEME 840 L NL RN++G MVP S+F T +W+ GP Q++ YNGYPA++++G +APG S+G+A+AEME Sbjct: 780 LLNLNVRNANGGMVPVSSFATVEWVRGPSQVVGYNGYPAIRVSGQSAPGYSSGDAIAEME 839 Query: 841 SFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLAVMLVV 900 +LP GFGFEWTGQSL+E SG+QAPAL LS++ VFL+LAALYES SIPL+VMLVV Sbjct: 840 RLARELPGGFGFEWTGQSLQEIQSGSQAPALIGLSVLFVFLLLAALYESWSIPLSVMLVV 899 Query: 901 PLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDLQAQGKGLIEATLE 960 PLG++G++ V LR MPNDVYF VG++A++GLSAKNAILIIEFAKDL+A+GK +AT+E Sbjct: 900 PLGVIGSVAAVMLRGMPNDVYFLVGLVAIIGLSAKNAILIIEFAKDLRAEGKSTYDATVE 959 Query: 961 AVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAV 1013 A HLRFRPI+MTSLAF LGVLP+AIASGA +ASQ AIGTGV+GGMI+AT+LA+ Sbjct: 960 AAHLRFRPILMTSLAFSLGVLPMAIASGASAASQNAIGTGVLGGMISATILAI 1012 >STM0475 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1049 Score = 1222 bits (3161), Expect = 0.0, Method: Compositional matrix adjust. Identities = 600/1019 (58%), Positives = 766/1019 (75%), Gaps = 6/1019 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M FFIDRP+FAWV+AI IMLAG LAI LPV+QYP IAPP + ++ATYPGA A+T+ D+ Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDT 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ MNG D L Y+ S S + G VQIT+TF T+ D+A V VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQGV V KS S+FL+ +G+ +TDG + + DY++ N+ + I R GVG QLFG+ Sbjct: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTSGVGDVQLFGS 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 + AMRIW++P +L LTP DV AI+AQNA VA G LG P QQ+ A+++ +L Sbjct: 181 QYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 TS ++FG I+L+ N +G+ VRLRDVA++E+GG++YD + +G+P+S +G++L+ ANAL Sbjct: 241 TSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYDVIAKFNGQPASGLGIKLATGANAL 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 TATA+ +++++ +FP G+K PYDT+ FVKISI EVVKTL+EAI+LVFLVM+LFLQ Sbjct: 301 DTATAIRAELKKMEPFFPPGMKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 N R T+IPTI VPV LLGTFA L FGFSIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 +EEGL P +ATRK+MGQI GAL+GI +VL AVFIPMAFFGG+ GAIYRQFS+++V++M Sbjct: 421 TEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHE-KKGFFGWFNRKFNSTASGYQGIIGGMLNKAGR 539 SVL+A LTPALCAT+LKPV KG H E KKGFFGWFNR F+ + Y +G +L GR Sbjct: 481 SVLVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRLFDKSTHHYTDSVGNILRSTGR 540 Query: 540 YMIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYL- 598 Y+++Y++IV + L+VRLP+SFLP+EDQG +T VQLP GA+ RT V+ ++ +YYL Sbjct: 541 YLLLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLN 600 Query: 599 KDPA-VEHAIAVLGYSFSGNGQNAALVFTPLKDWSQR-DKSQSADAIAGKAFGAFSQIKD 656 K+ A VE AV G+ F+G GQN + F LKDW+ R + +AI +A AFSQIKD Sbjct: 601 KEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEKNKVEAITQRATAAFSQIKD 660 Query: 657 AIVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILG-MASQSKVLAGVRPEG 715 A+VF N P I ELG ATGF F L D+AGLGH L QARNQ+ G +A +L GVRP G Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVRPNG 720 Query: 716 LEDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRR 775 LED PQ ++DID++KA ALGV S IN+ L A G SYVNDF + GR ++V V ++AK R Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 776 LQPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEA 835 + P+D+ + Y R S G MVPFSAF +++W G +L RYNG P+M+I G AAPG+STGEA Sbjct: 781 MLPDDINDWYVRGSDGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 Query: 836 MAEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLA 895 MA ME +KLP G G++WTG S +E+ SGNQAPALYA+SLI VFL LAALYES SIP + Sbjct: 841 MAMMEELASKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFS 900 Query: 896 VMLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDL-QAQGKGL 954 VMLVVPLG++GALL T R + NDVYF+VG++ +GLSAKNAILI+EFAKDL +GKGL Sbjct: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 Query: 955 IEATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAV 1013 +EATLEAV +R RPI+MTSLAF+LGV+PL I+SGAGS +Q A+GTGV+GGM+TATVLA+ Sbjct: 961 VEATLEAVRMRLRPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAI 1019 >acrB [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1049 Score = 1209 bits (3128), Expect = 0.0, Method: Compositional matrix adjust. Identities = 592/1019 (58%), Positives = 760/1019 (74%), Gaps = 6/1019 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M FFIDRP+FAWV+AI IMLAG LAI LPV+QYP IAPP + ++A+YPGA A+T+ D+ Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ MNG D L Y+ S S + G VQIT+TF T+ D+A V VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQGV V KS S+FL+ +G+ +TDG + + DY++ N+ + I R GVG QLFG+ Sbjct: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 + AMRIW++PN+L LTP DV AI+AQNA VA G LG P QQ+ A+++ +L Sbjct: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 TS E+FG I+L+ N +G+ V LRDVA++E+GG++YD +G+P+S +G++L+ ANAL Sbjct: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 TA A+ ++ ++ +FP+G+K PYDT+ FVKISI EVVKTL+EAI+LVFLVM+LFLQ Sbjct: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 N R T+IPTI VPV LLGTFA L FGFSIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 +EEGL P +ATRK+MGQI GAL+GI +VL AVF+PMAFFGG+ GAIYRQFS+++V++M Sbjct: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHE-KKGFFGWFNRKFNSTASGYQGIIGGMLNKAGR 539 SVL+A LTPALCAT+LKP+ KG H E KKGFFGWFNR F + Y +GG+L GR Sbjct: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 Query: 540 YMIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYL- 598 Y+++Y++IV + L+VRLP+SFLP+EDQG +T VQLP GA+ RT V+ ++ YYL Sbjct: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 Query: 599 -KDPAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQR-DKSQSADAIAGKAFGAFSQIKD 656 + VE AV G+ F+G GQN + F LKDW+ R + +AI +A AFSQIKD Sbjct: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 Query: 657 AIVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQS-KVLAGVRPEG 715 A+VF N P I ELG ATGF F L D+AGLGH L QARNQ+L A++ +L VRP G Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 Query: 716 LEDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRR 775 LED PQ ++DID++KA ALGV + IN+ L A G SYVNDF + GR ++V V ++AK R Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 776 LQPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEA 835 + P+D+ + Y R + G MVPFSAF +++W G +L RYNG P+M+I G AAPG+STGEA Sbjct: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 Query: 836 MAEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLA 895 M ME +KLP G G++WTG S +E+ SGNQAP+LYA+SLI VFL LAALYES SIP + Sbjct: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 Query: 896 VMLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDL-QAQGKGL 954 VMLVVPLG++GALL T R + NDVYF+VG++ +GLSAKNAILI+EFAKDL +GKGL Sbjct: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 Query: 955 IEATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAV 1013 IEATL+AV +R RPI+MTSLAFILGV+PL I++GAGS +Q A+GTGVMGGM+TATVLA+ Sbjct: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019 >ZacrB [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1049 Score = 1208 bits (3126), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/1019 (57%), Positives = 760/1019 (74%), Gaps = 6/1019 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M FFIDRP+FAWV+AI IMLAG LAI LPV+QYP IAPP + ++A+YPGA A+T+ D+ Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ MNG D L Y+ S S + G VQIT+TF T+ D+A V VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQGV + KS S+FL+ +G+ +TDG + + DY++ N+ + I R GVG QLFG+ Sbjct: 121 EVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 + AMRIW++PN+L LTP DV AI+AQNA VA G LG P QQ+ A+++ +L Sbjct: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 TS E+FG I+L+ N +G+ V LRDVA++E+GG++YD +G+P+S +G++L+ ANAL Sbjct: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 TA A+ ++ ++ +FP+G+K PYDT+ FVKISI EVVKTL+EAI+LVFLVM+LFLQ Sbjct: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 N R T+IPTI VPV LLGTFA L FGFSIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 +EEGL P +ATRK+MGQI GAL+GI +VL AVF+PMAFFGG+ GAIYRQFS+++V++M Sbjct: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHE-KKGFFGWFNRKFNSTASGYQGIIGGMLNKAGR 539 SVL+A LTPALCAT+LKP+ KG H E KKGFFGWFNR F + Y +GG+L GR Sbjct: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 Query: 540 YMIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYL- 598 Y+++Y++IV + L+VRLP+SFLP+EDQG +T VQLP GA+ RT V+ ++ YYL Sbjct: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 Query: 599 -KDPAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQR-DKSQSADAIAGKAFGAFSQIKD 656 + VE AV G+ F+G GQN + F LKDW+ R + +AI +A AFSQIKD Sbjct: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 Query: 657 AIVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQS-KVLAGVRPEG 715 A+VF N P I ELG ATGF F L D+AGLGH L QARNQ+L A++ +L VRP G Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 Query: 716 LEDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRR 775 LED PQ ++DID++KA ALGV + IN+ L A G SYVNDF + GR ++V V ++AK R Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 776 LQPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEA 835 + P+D+ + Y R + G MVPFSAF +++W G +L RYNG P+M+I G AAPG+STGEA Sbjct: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 Query: 836 MAEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLA 895 M ME +KLP G G++WTG S +E+ SGNQAP+LYA+SLI VFL LAALYES SIP + Sbjct: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 Query: 896 VMLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDL-QAQGKGL 954 VMLVVPLG++GALL T R + NDVYF+VG++ +GLSAKNAILI+EFAKDL +GKGL Sbjct: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 Query: 955 IEATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAV 1013 IEATL+AV +R RPI+MTSLAFILGV+PL I++GAGS +Q A+GTGVMGGM+TATVLA+ Sbjct: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019 >ECs0515 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1049 Score = 1208 bits (3126), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/1019 (57%), Positives = 760/1019 (74%), Gaps = 6/1019 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M FFIDRP+FAWV+AI IMLAG LAI LPV+QYP IAPP + ++A+YPGA A+T+ D+ Sbjct: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ MNG D L Y+ S S + G VQIT+TF T+ D+A V VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQGV + KS S+FL+ +G+ +TDG + + DY++ N+ + I R GVG QLFG+ Sbjct: 121 EVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 + AMRIW++PN+L LTP DV AI+AQNA VA G LG P QQ+ A+++ +L Sbjct: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 TS E+FG I+L+ N +G+ V LRDVA++E+GG++YD +G+P+S +G++L+ ANAL Sbjct: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 TA A+ ++ ++ +FP+G+K PYDT+ FVKISI EVVKTL+EAI+LVFLVM+LFLQ Sbjct: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 N R T+IPTI VPV LLGTFA L FGFSIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 +EEGL P +ATRK+MGQI GAL+GI +VL AVF+PMAFFGG+ GAIYRQFS+++V++M Sbjct: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHE-KKGFFGWFNRKFNSTASGYQGIIGGMLNKAGR 539 SVL+A LTPALCAT+LKP+ KG H E KKGFFGWFNR F + Y +GG+L GR Sbjct: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 Query: 540 YMIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYL- 598 Y+++Y++IV + L+VRLP+SFLP+EDQG +T VQLP GA+ RT V+ ++ YYL Sbjct: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 Query: 599 -KDPAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQR-DKSQSADAIAGKAFGAFSQIKD 656 + VE AV G+ F+G GQN + F LKDW+ R + +AI +A AFSQIKD Sbjct: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 Query: 657 AIVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQS-KVLAGVRPEG 715 A+VF N P I ELG ATGF F L D+AGLGH L QARNQ+L A++ +L VRP G Sbjct: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 Query: 716 LEDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRR 775 LED PQ ++DID++KA ALGV + IN+ L A G SYVNDF + GR ++V V ++AK R Sbjct: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 Query: 776 LQPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEA 835 + P+D+ + Y R + G MVPFSAF +++W G +L RYNG P+M+I G AAPG+STGEA Sbjct: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 Query: 836 MAEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLA 895 M ME +KLP G G++WTG S +E+ SGNQAP+LYA+SLI VFL LAALYES SIP + Sbjct: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 Query: 896 VMLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDL-QAQGKGL 954 VMLVVPLG++GALL T R + NDVYF+VG++ +GLSAKNAILI+EFAKDL +GKGL Sbjct: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 Query: 955 IEATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAV 1013 IEATL+AV +R RPI+MTSLAFILGV+PL I++GAGS +Q A+GTGVMGGM+TATVLA+ Sbjct: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAI 1019 >STM3391 [V] COG0841 Cation/multidrug efflux pump Sty Salmonella typhimurium LT2 Length = 1037 Score = 1207 bits (3123), Expect = 0.0, Method: Compositional matrix adjust. Identities = 587/1018 (57%), Positives = 753/1018 (73%), Gaps = 5/1018 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M FFI RP+FAWVLAI +M+AGALAI LPV+QYP IAPP + ++ATYPGA AQT+ D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAIMQLPVAQYPTIAPPAVSISATYPGADAQTVQDT 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ MNG D L Y+ S S + G V IT+TF T+PD+A V VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQG+ V KS S+FL+ G S + + DY++ N+ + I R+ GVG QLFG Sbjct: 121 EVQQQGISVEKSSSSFLMVAGFVSDNPNTTQDDISDYVASNIKDSISRLNGVGDVQLFGA 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 + AMRIW+D N L LTP DV ++ QN +A G LG P+ QQ+ A+++ +L Sbjct: 181 QYAMRIWLDANLLNKYQLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 PE+FG + LR N +G+ V L+DVAR+E+GG++Y+ R++GKP+S +G++L+ ANAL Sbjct: 241 KDPEEFGKVTLRVNTDGSVVHLKDVARIELGGENYNVVARINGKPASGLGIKLATGANAL 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 TATA+ K+ EL +FP G+K PYDT+ FVKISI EVVKTL EAI+LVFLVM+LFLQ Sbjct: 301 DTATAIKVKLAELQPFFPQGMKVVYPYDTTPFVKISIHEVVKTLFEAIILVFLVMYLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 NIR T+IPTI VPV LLGTFA L FG+SIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NIRATLIPTIAVPVVLLGTFAVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 E+ LSP +AT K+M QI GAL+GI +VL AVFIPMAFFGG+ GAIYRQFS+++V++M Sbjct: 421 MEDNLSPREATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHEKKGFFGWFNRKFNSTASGYQGIIGGMLNKAGRY 540 SVL+A LTPALCAT+LKPV HH +K GFFGWFN +F+ + + Y + G++ GRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHEKKSGFFGWFNTRFDHSVNHYTNSVSGIVRNTGRY 540 Query: 541 MIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYLKD 600 +I+Y+LIV + +L++RLP SFLP EDQG +T +QLP GA+ RT V+ Q+ YYL + Sbjct: 541 LIIYLLIVVGMAVLFLRLPTSFLPEEDQGVFLTMIQLPSGATQERTQKVLDQVTHYYLNN 600 Query: 601 PA--VEHAIAVLGYSFSGNGQNAALVFTPLKDWSQRD-KSQSADAIAGKAFGAFSQIKDA 657 VE V G+SFSG GQN+ + F LK W +R+ + S +A+ +A AFSQI+D Sbjct: 601 EKANVESVFTVNGFSFSGQGQNSGMAFVSLKPWEERNGEENSVEAVIARATRAFSQIRDG 660 Query: 658 IVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGM-ASQSKVLAGVRPEGL 716 +VFP N P I ELG ATGF F L D+ GLGH AL +ARNQ+LGM A +L VRP GL Sbjct: 661 LVFPFNMPAIVELGTATGFDFELIDQGGLGHDALTKARNQLLGMVAKHPDLLVRVRPNGL 720 Query: 717 EDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRRL 776 ED PQ +LD+D++KA ALGV S IN +S ALG YVNDF + GR ++V VQADA+ R+ Sbjct: 721 EDTPQFKLDVDQEKAQALGVSLSDINETISAALGGYYVNDFIDRGRVKKVYVQADAQFRM 780 Query: 777 QPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEAM 836 P D+ NLY R+++G MVPFS F +A+WI G +L RYNG P+M++ G AAPGRSTGEAM Sbjct: 781 LPGDINNLYVRSANGEMVPFSTFSSARWIYGSPRLERYNGMPSMELLGEAAPGRSTGEAM 840 Query: 837 AEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLAV 896 + ME+ ++LP G G++WTG S +E+ SGNQAPALYA+SLI VFL LAALYES SIP +V Sbjct: 841 SLMENLASQLPNGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSV 900 Query: 897 MLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDL-QAQGKGLI 955 MLVVPLG++GALL +LR + NDVYF+VG++ +GLSAKNAILI+EFAKDL + +G+GLI Sbjct: 901 MLVVPLGVVGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGRGLI 960 Query: 956 EATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAV 1013 EATLEA +R RPI+MTSLAFILGV+PL I+ GAGS +Q A+GTGVMGGM+TAT+LA+ Sbjct: 961 EATLEASRMRLRPILMTSLAFILGVMPLVISRGAGSGAQNAVGTGVMGGMLTATLLAI 1018 >CC0807 [V] COG0841 Cation/multidrug efflux pump Ccr Caulobacter vibrioides Length = 1051 Score = 1193 bits (3087), Expect = 0.0, Method: Compositional matrix adjust. Identities = 604/1032 (58%), Positives = 777/1032 (75%), Gaps = 5/1032 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 + +FFIDRP+FAWV+AI IMLAGALAI LP++QYP IA P + ++A YPGA+A+T++DS Sbjct: 2 LSRFFIDRPIFAWVIAIVIMLAGALAIRTLPIAQYPEIALPQVSISANYPGASAKTVEDS 61 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ+M G DGL Y+ S S +G +T+TF T+ D+A V VQN+L+ A LP Sbjct: 62 VTQVIEQKMKGLDGLDYMSSTSDGSGSATVTLTFKAGTDIDIAQVQVQNKLQTATALLPQ 121 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQG+ V KS NF++ IGL S D K L DY++ N+ + + RV GVG QLFG+ Sbjct: 122 EVQQQGLTVAKSARNFMMVIGLYSEDPKTTGADLADYMASNLQDPLSRVDGVGDIQLFGS 181 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPS-PGTQQIAATVVVNGQ 239 + AMRIW+DP KL +LTPADV AAI+AQNA V+ G +G P+ PGT + AT+ + Sbjct: 182 QYAMRIWLDPQKLASFSLTPADVAAAIRAQNAQVSAGQIGGTPNLPGTG-LNATITAQSR 240 Query: 240 LTSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANA 299 L +PEQF II++ + GATVRL DVARVE+G +SY + + +G ++ + ++L+P ANA Sbjct: 241 LQTPEQFRQIIVKNTSGGATVRLSDVARVELGAESYASIAKFNGYQAAGMAIKLAPGANA 300 Query: 300 LGTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFL 359 L TA AV+ +M +L K FP KY IPYD++ FVK+SIEEVVKTL+EAI+LVF+VMFLFL Sbjct: 301 LDTAAAVNARMAQLEKNFPANYKYVIPYDSTPFVKLSIEEVVKTLVEAIILVFIVMFLFL 360 Query: 360 QNIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERI 419 QN R T+IPTI VPV LLGTF L FG+SIN LTMFG+VLAIG+LVDDAIVVVENVER+ Sbjct: 361 QNWRATLIPTIAVPVVLLGTFGVLAAFGYSINTLTMFGLVLAIGLLVDDAIVVVENVERV 420 Query: 420 MSEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMV 479 MSEEGLSP +ATRK+M +I+GALIGI LVL AVF+PMAFFGG+ G IYRQFS+++V++M Sbjct: 421 MSEEGLSPKEATRKSMNEITGALIGIALVLAAVFVPMAFFGGSQGVIYRQFSITIVSAMA 480 Query: 480 FSVLMAFTLTPALCATILKPVEKGHHHEKKGFFGWFNRKFNSTASGYQGIIGGMLNKAGR 539 SV++A LTPAL AT+LKPV+ GHH EK GFFGWFNR FN +S YQG + +L K GR Sbjct: 481 LSVVVALVLTPALTATMLKPVKAGHHEEKTGFFGWFNRSFNDMSSRYQGSVRKILGKRGR 540 Query: 540 YMIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYL- 598 +M +Y I+ +GLL+VRLP++FLP EDQG + T VQLP GA+ +T AV+ Q+ +++L Sbjct: 541 WMAIYAAIIVAMGLLFVRLPSAFLPEEDQGTMFTLVQLPAGATEEKTLAVLDQVRDHFLV 600 Query: 599 -KDPAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQRDKSQ-SADAIAGKAFGAFSQIKD 656 + AV+ V G+SF+G GQNA L F LKD+ R + A A+AG+A GAFSQ +D Sbjct: 601 GEKEAVQSVFTVSGFSFAGAGQNAGLAFVRLKDFEHRKSANLKAQAVAGRAMGAFSQFRD 660 Query: 657 AIVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQSKVLAGVRPEGL 716 A+VF + PP + ELGN++GF F+LQD G+GH AL+ ARN +LGMASQ L GVRP G Sbjct: 661 AMVFAIVPPAVQELGNSSGFDFQLQDVGGVGHEALMNARNMMLGMASQDPSLVGVRPNGQ 720 Query: 717 EDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRRL 776 +D PQL++++D+ KA ALG+ + INS LS A G SYVNDF + GR ++V +QADA R+ Sbjct: 721 DDTPQLKIEVDQAKAGALGLTTADINSALSAAWGGSYVNDFIDRGRVKKVYMQADAPFRM 780 Query: 777 QPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEAM 836 PEDL Y RN+ G MV F AF TA W G +L RYNG ++ I G APG+S+G+A+ Sbjct: 781 TPEDLNRWYVRNNQGQMVAFPAFATASWTYGSPRLERYNGLSSVNIQGAPAPGKSSGDAI 840 Query: 837 AEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLAV 896 A ME AKLPPG G+EWTG S +E +GNQAPALYA+S++ VFL+LAALYES SIPLAV Sbjct: 841 AAMEKIAAKLPPGVGYEWTGLSAQELEAGNQAPALYAISILVVFLLLAALYESWSIPLAV 900 Query: 897 MLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDLQAQGKGLIE 956 ++V+PLG++GALL R + ND+YF+VG++ +GL+AKNAILI+EFAKDL +G GLIE Sbjct: 901 IMVIPLGVIGALLATFARGLSNDIYFQVGLLTTMGLAAKNAILIVEFAKDLYEKGMGLIE 960 Query: 957 ATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAVFLV 1016 ATLEAV LR RPIIMTSLAF+ GVLPLAI++GAGS +Q AIGTGV+GGMI+AT+LA+F V Sbjct: 961 ATLEAVRLRLRPIIMTSLAFVFGVLPLAISNGAGSGAQHAIGTGVIGGMISATLLAIFFV 1020 Query: 1017 PIFFVVVRKIFK 1028 P+FFVVV KIFK Sbjct: 1021 PLFFVVVEKIFK 1032 >YPO3133 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1050 Score = 1192 bits (3083), Expect = 0.0, Method: Compositional matrix adjust. Identities = 604/1051 (57%), Positives = 769/1051 (73%), Gaps = 9/1051 (0%) Query: 1 MGKFFIDRPVFAWVLAIFIMLAGALAITGLPVSQYPNIAPPTIVVTATYPGATAQTLDDS 60 M KFFIDRP+FAWV+AI IMLAGALAI LPV+QYP IAPP I + A YPGA A T+ ++ Sbjct: 1 MAKFFIDRPIFAWVIAIIIMLAGALAIMKLPVAQYPTIAPPAITIAANYPGADATTVQNT 60 Query: 61 VTSLIEQEMNGADGLQYIESQSQANGQVQITITFSPETNPDLAAVDVQNRLKRVEARLPA 120 VT +IEQ MNG D L Y+ S S ++G VQ+T+TF+ T+PD+A V VQN+L+ LP Sbjct: 61 VTQVIEQNMNGIDNLLYMSSSSDSSGNVQLTLTFNSGTDPDIAQVQVQNKLQLAMPLLPQ 120 Query: 121 AVTQQGVQVTKSRSNFLLFIGLSSTDGKLDPVALGDYLSRNVLNEIKRVPGVGQAQLFGT 180 V QQGV V KS S+FL+ G S DG + + DY+ N+ + I R PGVG QLFG+ Sbjct: 121 EVQQQGVSVEKSSSSFLMVAGFISEDGTMQQEDIADYVGSNIKDPISRTPGVGDVQLFGS 180 Query: 181 ERAMRIWIDPNKLIGLNLTPADVTAAIQAQNALVAGGTLGALPSPGTQQIAATVVVNGQL 240 + AMRIW+DP+KL LTP DV AI+ QN VA G LG P Q++ ++++ +L Sbjct: 181 QYAMRIWMDPHKLNNYKLTPVDVINAIKIQNNQVAAGQLGGTPPVPGQELNSSIIAQTRL 240 Query: 241 TSPEQFGNIILRANANGATVRLRDVARVEVGGQSYDTSGRLDGKPSSFIGVQLSPTANAL 300 T+ E+F I+L+ N +G+ VRL+DVA V++G +SY+ R +GKP++ IG++L+ ANAL Sbjct: 241 TNAEEFSQILLKVNTDGSQVRLKDVAIVKLGAESYNIIARYNGKPAAGIGIKLATGANAL 300 Query: 301 GTATAVHKKMEELAKYFPTGVKYTIPYDTSKFVKISIEEVVKTLIEAIVLVFLVMFLFLQ 360 T+ AV ++ +L +FP+G+ PYDT+ FVKISI EVVKTLIEAI+LVFLVM+LFLQ Sbjct: 301 NTSAAVKAELAKLQPFFPSGLTVVYPYDTTPFVKISINEVVKTLIEAIILVFLVMYLFLQ 360 Query: 361 NIRYTIIPTIVVPVALLGTFATLLLFGFSINVLTMFGMVLAIGILVDDAIVVVENVERIM 420 N R T+IPTI VPV LLGTFA L FG+SIN LTMFGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NFRATLIPTIAVPVVLLGTFAILSAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLSPADATRKAMGQISGALIGITLVLIAVFIPMAFFGGAVGAIYRQFSLSMVASMVF 480 EEGL P +AT+K+M QI GAL+GI LVL AVF+PMAFFGGA GAIYRQFS+++V++MV Sbjct: 421 QEEGLPPKEATKKSMEQIQGALVGIALVLSAVFVPMAFFGGATGAIYRQFSITIVSAMVL 480 Query: 481 SVLMAFTLTPALCATILKPVEKGHHHEKKGFFGWFNRKFNSTASGYQGIIGGMLNKAGRY 540 SVL+A LTPALCAT+LKP++KG H K GFFGWFN F + Y + +L GRY Sbjct: 481 SVLVALILTPALCATMLKPIKKGDHGPKTGFFGWFNNMFEKSTHHYTDSVANILRSTGRY 540 Query: 541 MIVYVLIVACVGLLYVRLPASFLPNEDQGYIITNVQLPPGASTSRTTAVVKQIEEYYL-- 598 +++Y+ IV + +L++RLP+SFLP EDQG +T VQLP GA+ RT V+ + +YYL Sbjct: 541 LVIYLAIVIGMAVLFMRLPSSFLPEEDQGVFLTMVQLPAGATQERTQKVLNHVTDYYLDK 600 Query: 599 KDPAVEHAIAVLGYSFSGNGQNAALVFTPLKDWSQRDKSQS-ADAIAGKAFGAFSQIKDA 657 + V V G+ FSG GQN L F LK+W +R Q+ AI +A AFS+IKD Sbjct: 601 EKNVVNSVFTVNGFGFSGQGQNTGLAFVSLKNWDERKGEQNKVPAIVSRASAAFSKIKDG 660 Query: 658 IVFPLNPPPIPELGNATGFTFRLQDRAGLGHTALVQARNQILGMASQS-KVLAGVRPEGL 716 +VF N P I ELG ATGF F+L D+ LGH L ARNQ+LGMA+Q +L GVRP GL Sbjct: 661 MVFAFNLPAIVELGTATGFDFQLIDQGNLGHQQLTDARNQLLGMAAQHPDMLVGVRPNGL 720 Query: 717 EDAPQLQLDIDRDKANALGVPFSTINSVLSTALGSSYVNDFPNLGRQQRVIVQADAKRRL 776 ED PQ ++++D++KA ALGV S IN+ L +A+G SYVNDF + GR ++V VQADA R+ Sbjct: 721 EDTPQFKVEVDQEKAQALGVAISDINTTLGSAMGGSYVNDFIDRGRVKKVYVQADAPFRM 780 Query: 777 QPEDLTNLYARNSSGTMVPFSAFVTAKWINGPVQLIRYNGYPAMKIAGGAAPGRSTGEAM 836 P+D+ Y RN+ G MV F+ F TAKW G +L RYNG P+M+I G AAPG+STGEAM Sbjct: 781 LPDDIDKWYVRNNMGQMVSFATFSTAKWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAM 840 Query: 837 AEMESFVAKLPPGFGFEWTGQSLEEKTSGNQAPALYALSLIAVFLVLAALYESTSIPLAV 896 M+ AKLP G G++WTG S +E+ SGNQAPALYA+SLI VFL LAALYES SIP +V Sbjct: 841 DLMQELAAKLPSGVGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSV 900 Query: 897 MLVVPLGILGALLGVTLRAMPNDVYFKVGMIAVVGLSAKNAILIIEFAKDL-QAQGKGLI 955 MLVVPLG++GALL TLR + NDVYF+VG++ +GLSAKNAILI+EFAKDL +GKGL+ Sbjct: 901 MLVVPLGVVGALLAATLRGLENDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLV 960 Query: 956 EATLEAVHLRFRPIIMTSLAFILGVLPLAIASGAGSASQRAIGTGVMGGMITATVLAVFL 1015 E+TLE+V +R RPI+MTSLAFILGV+PL I+SGAGS +Q A+GTGVMGGMITATVLA+F Sbjct: 961 ESTLESVRMRLRPILMTSLAFILGVMPLVISSGAGSGAQNAVGTGVMGGMITATVLAIFF 1020 Query: 1016 VPIFFVVVRKIFKGSERQRKFDAEHSPKINS 1046 VP+FFVVVR+ F ++ D EHS +N+ Sbjct: 1021 VPLFFVVVRRRFS----RKTDDIEHSHPVNT 1047