BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0166.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Z1554 [M] COG4591 ABC-type transport system, involved in lipopro... 152 2e-36 ECs1294 [M] COG4591 ABC-type transport system, involved in lipop... 152 2e-36 VCA0854 [M] COG4591 ABC-type transport system, involved in lipop... 119 1e-26 AF1017 [V] COG0577 ABC-type antimicrobial peptide transport syst... 79 3e-14 MJ0797 [V] COG0577 ABC-type antimicrobial peptide transport syst... 74 9e-13 BS_ytrF [V] COG0577 ABC-type antimicrobial peptide transport sys... 71 5e-12 AF1470 [V] COG0577 ABC-type antimicrobial peptide transport syst... 71 6e-12 MJ1507 [V] COG0577 ABC-type antimicrobial peptide transport syst... 71 7e-12 VNG0003C [V] COG0577 ABC-type antimicrobial peptide transport sy... 66 1e-10 MA0447 [V] COG0577 ABC-type antimicrobial peptide transport syst... 65 4e-10 >Z1554 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component EcZ Escherichia coli O157:H7 EDL933 Length = 436 Score = 152 bits (384), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 124/451 (27%), Positives = 229/451 (50%), Gaps = 47/451 (10%) Query: 2 KTLSIAFRNLLRNRRRSLRTLLAMVVGMSAVLLFGGYANNVNYVLQTNFVRSE-GHLQIQ 60 + + AF NL R++RRS T+ A+V+G A+ L+GG+ + ++L+ +R+ GH+QI Sbjct: 28 RDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFLYGGFIDYSFWILKEQTIRTNIGHVQIY 87 Query: 61 RKNYFLYGAGDPMAFSIDRYQHVIDTVRSDSVLSSLVTVVTPLLAVSGIAGNYGAGVSST 120 ++YF + I Y + + SD L++ ++ ++ L +G+ +Y + SS Sbjct: 88 NQHYF--ETSNKNKSLIADYAALKKAILSDPTLAADISTLSGQLEFTGVISHYESETSSY 145 Query: 121 VIGIGVVVADQNRMRQWNDYGFSKQMKPLSLTSTSADSVVIGTGLGRILRLCGPLSIPNC 180 +GV ++ F K + L+ D + +G+GL Sbjct: 146 FSALGVEPLPALKLGS-----FDKIIAGSDLSRVKGDEITLGSGLA-------------- 186 Query: 181 ALNGVRKTENAATSA--DIAQLRSARGGESRXGAPNVAQLAVVKAESQGVRAVDDRYLQL 238 KT NA D+ + +A GG+ GA ++ + ++ G++ DD +++ Sbjct: 187 ------KTLNAKYDDWLDVMVVNTA-GGQ---GALSLKMRGIFES---GIKDYDDVAMKI 233 Query: 239 HLGQAQKLIYGSEPGKATAIAVQLHHTSDQSAAIQRIRQ-LEATTLRQDDLDVLDFQTLT 297 L AQ+++ G++ I ++ T+ SA ++RQ +E L L V D++ ++ Sbjct: 234 PLDTAQRMM-GTDGVSKVLILLKEDDTAAFSA---KLRQFIERNHL---PLVVKDWRDVS 286 Query: 298 PQYQQITGMFNAIFGFVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFGVLRI 357 YQQ+ G+ + I+ F+ L++ +IV+FM+GN+M+M ++ERT EI TLRAIG++ V R+ Sbjct: 287 LFYQQVEGLLSGIYFFIKLIVALIVIFMIGNSMAMNIVERTREITTLRAIGLKPLHVTRL 346 Query: 358 FLLEGALLGVLGALIGALCALAAAWMINHAGFHWTPPGEIDPVQFTVRVFGETKMIVGYA 417 FL EG +GV+GA+ L AW+IN G PP + +T + ++ Sbjct: 347 FLTEGIFIGVIGAVGSLLVGGVLAWIINLYGIA-MPPSPGQTIGYTAFIKTSNPELIWVT 405 Query: 418 IGI-VAISTLSAFWPARRAARMPIVSALSYA 447 + + + +T ++ PA RA+R+ I A ++ Sbjct: 406 VVLPILTATGASVLPALRASRLNISDAFKFS 436 >ECs1294 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component Ecs Escherichia coli O157:H7 Length = 436 Score = 152 bits (384), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 124/451 (27%), Positives = 229/451 (50%), Gaps = 47/451 (10%) Query: 2 KTLSIAFRNLLRNRRRSLRTLLAMVVGMSAVLLFGGYANNVNYVLQTNFVRSE-GHLQIQ 60 + + AF NL R++RRS T+ A+V+G A+ L+GG+ + ++L+ +R+ GH+QI Sbjct: 28 RDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFLYGGFIDYSFWILKEQTIRTNIGHVQIY 87 Query: 61 RKNYFLYGAGDPMAFSIDRYQHVIDTVRSDSVLSSLVTVVTPLLAVSGIAGNYGAGVSST 120 ++YF + I Y + + SD L++ ++ ++ L +G+ +Y + SS Sbjct: 88 NQHYF--ETSNKNKSLIADYAALKKAILSDPTLAADISTLSGQLEFTGVISHYESETSSY 145 Query: 121 VIGIGVVVADQNRMRQWNDYGFSKQMKPLSLTSTSADSVVIGTGLGRILRLCGPLSIPNC 180 +GV ++ F K + L+ D + +G+GL Sbjct: 146 FSALGVEPLPALKLGS-----FDKIIAGSDLSRVKGDEITLGSGLA-------------- 186 Query: 181 ALNGVRKTENAATSA--DIAQLRSARGGESRXGAPNVAQLAVVKAESQGVRAVDDRYLQL 238 KT NA D+ + +A GG+ GA ++ + ++ G++ DD +++ Sbjct: 187 ------KTLNAKYDDWLDVMVVNTA-GGQ---GALSLKMRGIFES---GIKDYDDVAMKI 233 Query: 239 HLGQAQKLIYGSEPGKATAIAVQLHHTSDQSAAIQRIRQ-LEATTLRQDDLDVLDFQTLT 297 L AQ+++ G++ I ++ T+ SA ++RQ +E L L V D++ ++ Sbjct: 234 PLDTAQRMM-GTDGVSKVLILLKEDDTAAFSA---KLRQFIERNHL---PLVVKDWRDVS 286 Query: 298 PQYQQITGMFNAIFGFVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFGVLRI 357 YQQ+ G+ + I+ F+ L++ +IV+FM+GN+M+M ++ERT EI TLRAIG++ V R+ Sbjct: 287 LFYQQVEGLLSGIYFFIKLIVALIVIFMIGNSMAMNIVERTREITTLRAIGLKPLHVTRL 346 Query: 358 FLLEGALLGVLGALIGALCALAAAWMINHAGFHWTPPGEIDPVQFTVRVFGETKMIVGYA 417 FL EG +GV+GA+ L AW+IN G PP + +T + ++ Sbjct: 347 FLTEGIFIGVIGAVGSLLVGGVLAWIINLYGIA-MPPSPGQTIGYTAFIKTSNPELIWVT 405 Query: 418 IGI-VAISTLSAFWPARRAARMPIVSALSYA 447 + + + +T ++ PA RA+R+ I A ++ Sbjct: 406 VVLPILTATGASVLPALRASRLNISDAFKFS 436 >VCA0854 [M] COG4591 ABC-type transport system, involved in lipoprotein release, permease component Vch Vibrio cholerae Length = 419 Score = 119 bits (298), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 120/454 (26%), Positives = 207/454 (45%), Gaps = 47/454 (10%) Query: 2 KTLSIAFR----NLLRNRRRSLRTLLAMVVGMSAVLLFGGYANNVNYVLQTNFVRSEGHL 57 K +S A+R NL RNRRRSL ++ + + + A+ GG+ L+ + R GHL Sbjct: 3 KLISQAWRLAALNLQRNRRRSLLSISIIAIAVLALTSAGGFGLYTYDSLRESTARDVGHL 62 Query: 58 QIQRKNYFLYGAGDPMAFSIDRYQHVIDTVRSDSVLSSLVTVVTPLLAVSGIAGNYGAGV 117 + ++ YF P+A ++ H+ + ++ + + P + ++G+ N G Sbjct: 63 TLSQRGYFAQEEETPLANGLEGSDHIRQVLLANPAIRG----IQPRIELTGLVSN---GQ 115 Query: 118 SSTV-IGIGVVVADQNRMRQWNDY--GFSKQMKPLSLTSTSADSVVIGTGLGRILRLCGP 174 ST+ +G+GV + + + D G + Q + V++G L R Sbjct: 116 KSTIFVGLGVDDKEFDMKGPFLDLRAGQTLQDPKSPRFDPTQPQVMLGVDLAR------- 168 Query: 175 LSIPNCALNGVRKTENAATSADIAQLRSARGGESRXGAPNVAQLAVVKAESQGVRAVDDR 234 N ++ AT+AD GA N V S GV +D R Sbjct: 169 ----NLSVGVGDWVTLLATTAD--------------GALNALDFQVRGLYSTGVPELDKR 210 Query: 235 YLQLHLGQAQKLIYGSEPGKATAIAVQLHHTSD-QSAAIQRIRQLEATTLRQDDLDVLDF 293 L LHL AQ+L+ S K + ++V L +T + Q+ QL +L Q+ L V + Sbjct: 211 QLYLHLASAQELLNSS---KVSTLSVYLFNTENTQTLQTWVENQLNQLSLSQE-LQVTPW 266 Query: 294 QTLTPQYQQITGMFNAIFGFVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFG 353 Q L Y ++ +++ +FG + ++ ++V + NT++M+V ERT EIGTL A+G Sbjct: 267 QQLAFFYTRVKDLYDRLFGVMGTVMAMVVFVALFNTLTMSVSERTREIGTLSALGAYPSD 326 Query: 354 VLRIFLLEGALLGVLGALIGALCALAAAWMINHAGFHW-TPPGEIDPVQFTVRVFGETKM 412 +L F+ E LL + G+L+G L + A PPG + + + ++ + Sbjct: 327 ILAGFVREATLLALCGSLLGTLLTGITIVAVRVADIQMPPPPGRTE--GYPLDLYFSFTL 384 Query: 413 IVGYAIGIVAISTLSAFWPARRAARMPIVSALSY 446 + +G V I L+A++ AR+ PI AL+Y Sbjct: 385 VGFCTLGTVLICVLAAWFSARKGVNKPITEALAY 418 >AF1017 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Afu Archaeoglobus fulgidus Length = 377 Score = 78.6 bits (192), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 57/192 (29%), Positives = 94/192 (48%), Gaps = 22/192 (11%) Query: 259 AVQLHHTSDQSAAIQRIRQLEATTLRQDDLDVLDFQTLTPQ----YQQITGMFNAIFGFV 314 A L D I+ E R + + V D + + + + QI AI Sbjct: 203 AESLEKVDDVKKEIE-----EKINSRDEKVVVFDLKIILERINEAFSQINTFLMAIASVS 257 Query: 315 ALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFGVLRIFLLEGALLGVLGALIGA 374 L+ GV ++ N M M+ +ERT EIG +RAIG R +LRIFL+E +LG++G+ IG+ Sbjct: 258 LLVAGVSIL----NIMLMSTIERTKEIGIMRAIGAYRSTILRIFLMEALILGLIGSAIGS 313 Query: 375 LCALAAAWMINHAGFHWTPPGEIDPVQFTVRVFGETKMIVGYAIGIVAISTLSAFWPARR 434 + ++A + I+ + R+ + +G++IG V +S LS +PA + Sbjct: 314 VLSIAGGYAIDLMILQ--------DASYVFRLSTLLYISLGFSIG-VMVSVLSGLYPAWK 364 Query: 435 AARMPIVSALSY 446 A+R+ + AL Y Sbjct: 365 ASRLEPIEALRY 376 >MJ0797 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Mja Methanococcus jannaschii Length = 367 Score = 73.6 bits (179), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 40/119 (33%), Positives = 70/119 (58%), Gaps = 12/119 (10%) Query: 326 VGNTMSMAVMERTIEIGTLRAIGVRRFGVLRIFLLEGALLGVLGALIGALCALAAAWMIN 385 +GN M M+V+ERT EIG +R+IG + ++ +FL E +LGV+G+LIGA +L ++I Sbjct: 258 IGNVMLMSVVERTTEIGVMRSIGASKKDIIILFLYEALILGVIGSLIGAFLSLFFGYLIV 317 Query: 386 HAGFHWTPPGEIDPVQFTVRVFGETKMIVGYAIGIVAISTLSAFWPARRAARMPIVSAL 444 H ++ ++ + MI+G GI+ S +SA +PA +A+++ + +L Sbjct: 318 HY-----------LLKTSLSYYAIFYMIIGIIFGILT-SLISALYPAYKASKLDPIKSL 364 >BS_ytrF [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Bsu Bacillus subtilis Length = 436 Score = 71.2 bits (173), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 47/137 (34%), Positives = 79/137 (57%), Gaps = 9/137 (6%) Query: 312 GFVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFGVLRIFLLEGALLGVLGAL 371 G +A++I I +F NTM+MAV ERT EIG ++AIG + R+FL+E A +G+LG + Sbjct: 301 GCIAVIISAIGIF---NTMTMAVTERTQEIGIMKAIGASPSIIRRMFLMESAYIGILGCV 357 Query: 372 IGALCALAAAWMINHAG---FHWTPPGEIDPVQFTVRVFGETKMIVGYAI-GIVAISTLS 427 IG + + ++++N A T G+ + +T + +I+ I G VA+ +S Sbjct: 358 IGIIISYGVSYLVNLAVPMILAATSGGDAGDLNYTFSYIPASLVIIAVVICGGVAV--IS 415 Query: 428 AFWPARRAARMPIVSAL 444 PAR+A + +++AL Sbjct: 416 GMNPARKATKTNVLTAL 432 >AF1470 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Afu Archaeoglobus fulgidus Length = 409 Score = 70.9 bits (172), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 51/173 (29%), Positives = 92/173 (53%), Gaps = 21/173 (12%) Query: 281 TTLRQDD--LDVLDFQTLTPQYQQ----ITGMFNAIFGFVALLIGVIVMFMVGNTMSMAV 334 +TL + D +D+ DF++L ++ +T AI L+ GV ++ N M M+ Sbjct: 250 STLNKKDEKVDIRDFESLIESVEESLNSMTQFLMAIAAVSLLVAGVSIL----NIMLMST 305 Query: 335 MERTIEIGTLRAIGVRRFGVLRIFLLEGALLGVLGALIGALCALAAAW-MINHAGFHWTP 393 +ERT EIG +RAIG R ++ IFLLE +LG+ G++ GA+ ++A + +I+ GF Sbjct: 306 IERTKEIGVMRAIGAFRENIMMIFLLEALILGLTGSVFGAVMSVAGGYAIISMMGF---- 361 Query: 394 PGEIDPVQFTVRVFGETKMIVGYAIGIVAISTLSAFWPARRAARMPIVSALSY 446 + + + G+A+G++ + S +PA +A+++ + AL Y Sbjct: 362 -----STAYVLHPSSALYIAEGFAVGVLT-AVASGLYPAWKASKLEPIEALRY 408 >MJ1507 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Mja Methanococcus jannaschii Length = 399 Score = 70.9 bits (172), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 54/216 (25%), Positives = 100/216 (46%), Gaps = 16/216 (7%) Query: 232 DDRYLQLHLGQAQKLIYGSEPGKATAIAVQLHHTSDQSAAIQRIRQLEATTLRQDDLDVL 291 DD + L++ +KL +G+E GK I+V + D + I++ + +D VL Sbjct: 194 DDNSIILNIDVGEKL-FGNE-GKYNFISVTVKEGEDIEKVSEEIKKALKKSFGDEDFSVL 251 Query: 292 DFQTLTPQYQQITG---MFNAIFGFVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIG 348 + L + G +F ++LL+G + + NTM M+++ER +IG L+A+G Sbjct: 252 TAEQLAKTVSSVLGVITIFVVGVAAISLLVGAV---GISNTMHMSILERRKDIGILKALG 308 Query: 349 VRRFGVLRIFLLEGALLGVLGALIGALCALAAAWMINHAGFHWTPPGEIDPVQFTVRVFG 408 +L IF++E LG+ G ++G + + A +I V + Sbjct: 309 AETTDILAIFVVESGFLGLFGGIVGLVLGILLAEVIEALAHKMG--------YLMVNAWI 360 Query: 409 ETKMIVGYAIGIVAISTLSAFWPARRAARMPIVSAL 444 ++IVG I + +S ++PAR A++ + L Sbjct: 361 SWELIVGVLIFSFLVGVISGYFPARSGAKLNPIETL 396 >VNG0003C [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Hbs Halobacterium sp. NRC-1 Length = 369 Score = 66.2 bits (160), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 49/135 (36%), Positives = 71/135 (52%), Gaps = 14/135 (10%) Query: 311 FGFVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFGVLRIFLLEGALLGVLGA 370 G ++LL+ + + N M M+ +ER EIG LRA+G+RR VLR+ L E LG +G Sbjct: 246 IGSISLLVASVAIL---NVMLMSTIERRGEIGVLRAVGIRRGEVLRMILTEAMFLGAVGG 302 Query: 371 LIGALCALAAAWMINHAGFHWTPPGEIDPVQFTVRVFGETKMIV-GYAIGIVAISTLSAF 429 L+G+L +L I F +D V V+ +K +V G+ + A S LS Sbjct: 303 LVGSLASLGVGAFI----FDKITQNAMD-----VLVWPSSKYLVYGFLFAVFA-SLLSGL 352 Query: 430 WPARRAARMPIVSAL 444 +PA +AA P V AL Sbjct: 353 YPAWKAANDPPVEAL 367 >MA0447 [V] COG0577 ABC-type antimicrobial peptide transport system, permease component Mac Methanosarcina acetivorans str.C2A Length = 403 Score = 64.7 bits (156), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 43/134 (32%), Positives = 74/134 (55%), Gaps = 17/134 (12%) Query: 313 FVALLIGVIVMFMVGNTMSMAVMERTIEIGTLRAIGVRRFGVLRIFLLEGALLGVLGALI 372 ++LL+G I + N M ++V ERT EIG L+++G F +L +F++E LLGV G ++ Sbjct: 286 LISLLVGSIGIM---NIMLVSVTERTREIGVLKSLGFTGFDILFLFMVESILLGVFGGIL 342 Query: 373 GALCALAAAWMINHAGFHWTPPGEIDPVQFTVRVFGETKMIVGYAIGIVAISTLSAFWPA 432 G +A A+ + + + PV F + + + G+ + VA+ +S +PA Sbjct: 343 GGAVGIAGAYSV-ESLLNL-------PVVFPLSL-----IFAGFIVA-VAVGFVSGVYPA 388 Query: 433 RRAARMPIVSALSY 446 R+AA+M V +L Y Sbjct: 389 RKAAKMKPVDSLRY 402