BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0116.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 274 3e-73 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 251 2e-66 PA2006 [GEPR] COG0477 Permeases of the major facilitator superfa... 248 3e-65 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 246 1e-64 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 246 1e-64 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 241 3e-63 STM2179 [GEPR] COG0477 Permeases of the major facilitator superf... 231 3e-60 PA2472 [GEPR] COG0477 Permeases of the major facilitator superfa... 227 4e-59 PA4900 [GEPR] COG0477 Permeases of the major facilitator superfa... 209 8e-54 RSp1595 [GEPR] COG0477 Permeases of the major facilitator superf... 187 4e-47 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 274 bits (701), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 169/441 (38%), Positives = 247/441 (56%), Gaps = 16/441 (3%) Query: 7 IQVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFS 66 I V +D + QWS + C + +DGFDT +G +APA++++ I A G +FS Sbjct: 8 IDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTVFS 67 Query: 67 AGLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGL 126 AGL G++VGA+I GPLADR GRK ++ AFG S+L+A A + L+ LRFLTG+GL Sbjct: 68 AGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGLGL 127 Query: 127 GGALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGA 186 GGA+PNA+AL SEY P R + + CG LG+ GGIV + L+P GW +V + GG Sbjct: 128 GGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFGGV 187 Query: 187 LP---IAVALFALAFMPESARFLLVRGKHRARLQALMRRIAP-ELGADQDL---AAPPPQ 239 +P + V +FAL PES R+L+ +G A + L+ RIAP ++ D Sbjct: 188 IPLLLLPVMVFAL---PESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKG 244 Query: 240 APGVPVAELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCF 299 APG PV +LF T+LLW +FM+L+++Y + +W+P ++ +++ + Sbjct: 245 APGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMY 304 Query: 300 SAGGVLGSLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQ 359 GG +G+L+ G +M+ L L A L L Q + V+ +G I Sbjct: 305 QLGGTVGALVIGRMMDRYPATVVLCCTYGLGAGF-LVLTGVSQGTMLAIAVTG-VGFCIS 362 Query: 360 GAQAGLNVLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGIT 419 G+Q G N A + YPTA R TG+ +ALGIGR+GS+CG L G ++L + + +FL+ Sbjct: 363 GSQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAV 422 Query: 420 PAVIAALAIVF----NRRAET 436 PA IA+LAI R ET Sbjct: 423 PAAIASLAIFLCGAQARHVET 443 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 251 bits (642), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 153/410 (37%), Positives = 234/410 (57%), Gaps = 3/410 (0%) Query: 7 IQVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFS 66 + V I+A+P+ QW + C LI LDG DT +G +APA++++ GI AS GP+ S Sbjct: 12 LDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGIDRASLGPVMS 71 Query: 67 AGLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGL 126 A L+GM+ GA+ GPLADR+GRK +++ A FG SL +A + + LL LRFLTG+GL Sbjct: 72 AALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLALRFLTGLGL 131 Query: 127 GGALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGA 186 G A+PNA L SEY+P R ++V ++ CG LG GG V++ L+P GWH++ ++GG Sbjct: 132 GAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGWHSLLLLGGL 191 Query: 187 LPIAVALFALAFMPESARFLLVRGKHRARLQALMRRIAP-ELGADQDLAAPPPQAPGVP- 244 LP+ +A+ L +PESAR+L+VR + R++ ++ IAP ++ + P Q Sbjct: 192 LPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHVPEQQTVQARN 251 Query: 245 -VAELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGG 303 A +F T+LLW+ YFM LV++Y + SW+P ++ + + + F GG Sbjct: 252 VFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAFIGALFQFGG 311 Query: 304 VLGSLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQGAQA 363 VL ++ GW M+ + + L L + A + + + L G+ I GAQ+ Sbjct: 312 VLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLLAGMCINGAQS 371 Query: 364 GLNVLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHI 413 + LA YPT RATGV + LGIGR G+I G G+ +LG + + + Sbjct: 372 AMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWNFEQV 421 >PA2006 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 450 Score = 248 bits (632), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 165/419 (39%), Positives = 241/419 (57%), Gaps = 4/419 (0%) Query: 13 IDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFSAGLLGM 72 +DARPV QW + L+ V DG+D Q +G + P +++E G+ A+FGP+FSA L G+ Sbjct: 12 LDARPVSRYQWLLLLLLALLLVTDGYDAQVLGYVVPTLAQEWGLDKAAFGPVFSANLFGL 71 Query: 73 LVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGLGGALPN 132 VG++++ PLADRFG + +++ L + S+++L A + + L+L RF+ GIG+GGA+P+ Sbjct: 72 TVGSLLVTPLADRFGIRRVLLCCVLIYASLTVLMVFAGSLESLMLARFVCGIGMGGAMPS 131 Query: 133 ALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGALPIAVA 192 A+AL +EYSP R ++V CG G GG V + + GW AVF+ GG P+ + Sbjct: 132 AMALMAEYSPPRLRTLMVTLAACGFSFGGAAGGFVAAAFMDGFGWQAVFLAGGVTPLLLF 191 Query: 193 LFALAFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLAAPPPQAPGVPVAELFRQG 252 F L F+PES LL ARL+ L R+AP A A + V ELFR G Sbjct: 192 PFLLLFLPESLPRLLRDAPPYARLRQLSERMAPGWQPPPAEAD-AEPAASLTVLELFRHG 250 Query: 253 RWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGGVLGSLLQGW 312 + T+LLW +F++L++LYF+VSW+P++L + + A S F G LG++L W Sbjct: 251 YARPTLLLWATFFVSLILLYFMVSWLPSLLQESGLTRNAANLATSMFLFAGTLGAMLLAW 310 Query: 313 LMNAL--GVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQGAQAGLNVLAT 370 L + L VR + L Q W + V + G I G Q LN A+ Sbjct: 311 LADRLRSKVRLLAAILAGAALFTLLLGLNHDQPRWLLAFVFA-AGFCIIGGQLTLNAFAS 369 Query: 371 EIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAALAIV 429 YP +RATG G+ALG+GR GSI GPL GSL+LG + V++IF++ PA +AAL I+ Sbjct: 370 NFYPAQVRATGTGWALGVGRFGSILGPLFGSLLLGMHISVENIFMLAAIPAGLAALLIL 428 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 246 bits (627), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 150/420 (35%), Positives = 228/420 (54%), Gaps = 1/420 (0%) Query: 8 QVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFSA 67 + +IDA PVG +QW I C L+ +LDGFDT IG +AP + + P+F A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGA 65 Query: 68 GLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGLG 127 GLLG+ GA++ GPL+DRFGRK ++ FG++SL +A + L+ LRFLTG+GLG Sbjct: 66 GLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 128 GALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGAL 187 GA+PN + + SEY P R +V + CG LG+ GGIV++ L+P GWH + ++GG L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 188 PIAVALFALAFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLA-APPPQAPGVPVA 246 P+ + + L +PES R+ + R +A + + I E D + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKGSIR 245 Query: 247 ELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGGVLG 306 +LF + T++LW+ +FM+L+++Y + SWMP +L + + F GG LG Sbjct: 246 QLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLG 305 Query: 307 SLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQGAQAGLN 366 +L G LM+ R L L A+ A+ + + W + + G+ I G+Q GLN Sbjct: 306 ALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLN 365 Query: 367 VLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAAL 426 L +YPT RATGV ++ IGR G+I G L+G +M+ +F + PA I+A+ Sbjct: 366 ALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAV 425 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 246 bits (627), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 149/420 (35%), Positives = 227/420 (54%), Gaps = 1/420 (0%) Query: 8 QVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFSA 67 + +IDA PVG +QW I C L+ +LDGFDT IG +AP + + P+F A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 68 GLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGLG 127 GLL + GA++ GPL+DRFGRK ++ FG++SL +A + L+ LRFLTG+GLG Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 128 GALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGAL 187 GA+PN + + SEY P R +V + CG LG+ GGIV++ L+P GWH + ++GG L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 188 PIAVALFALAFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLA-APPPQAPGVPVA 246 P+ + + L +PES R+ + R +A + + I E D + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKGSIR 245 Query: 247 ELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGGVLG 306 +LF + T++LW+ +FM+L+++Y + SWMP +L + + F GG LG Sbjct: 246 QLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLG 305 Query: 307 SLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQGAQAGLN 366 +L G LM+ R L L A+ A+ + + W + + G+ I G+Q GLN Sbjct: 306 ALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLN 365 Query: 367 VLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAAL 426 L +YPT RATGV ++ IGR G+I G L+G +M+ +F + PA I+A+ Sbjct: 366 ALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAV 425 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 241 bits (615), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 155/414 (37%), Positives = 231/414 (55%), Gaps = 9/414 (2%) Query: 7 IQVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFS 66 + V EVID + Q + C A+LDGFDT IG +APA+ + P F Sbjct: 10 VPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLTPPQLAPAFG 69 Query: 67 AGLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGL 126 AGL G+++G+M LGP+ADRFGRK +++ + L FG +L AA+ + + L++LRFLTG+GL Sbjct: 70 AGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVMLRFLTGLGL 129 Query: 127 GGALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGA 186 GGA+P + L++EYSP+RH ++V G G LGG+V + +LP +GW V + GG Sbjct: 130 GGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGWRGVLVAGGV 189 Query: 187 LPIAVALFALAFMPESARFLLVRGKHRARLQALMRRIA-PELGADQDLAAPPPQAPGVPV 245 P+ + +MPES +FL R + L+ ++ RIA + G P G P Sbjct: 190 TPLVLLPVLALWMPESVQFLAQRPQCADALRQIVTRIAGHDHGDGVTFIGDRPAQEGAPF 249 Query: 246 --AELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGG 303 LF G + TVLLW +F +L V Y + SW+P V+ ++ + GG Sbjct: 250 PGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLTEAARVGAMVPLGG 309 Query: 304 VLGSLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVV---IQG 360 +G++ LM+ G R L+ A Y A+A+A + NV +++++ VV I G Sbjct: 310 TIGAIALALLMDRAGSPRALI---AAYFCGAIAVAAIGLAIGNVAALTAVVFVVGFGIAG 366 Query: 361 AQAGLNVLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIF 414 AQ G+N+LA ++YPT RATGV +ALG+GR GSI G L G ++ V+ +F Sbjct: 367 AQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSVQTLF 420 >STM2179 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 452 Score = 231 bits (588), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 160/422 (37%), Positives = 238/422 (56%), Gaps = 5/422 (1%) Query: 8 QVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFSA 67 + +IDA PVG +QW I C L+ +LDGFDT IG +AP + + + P+F A Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLSASELAPLFGA 65 Query: 68 GLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGLG 127 GLLG+ GA++ GPLADRFGRK ++ FG++SLL+A + + L+LLRFLTG+GLG Sbjct: 66 GLLGLTAGALLCGPLADRFGRKRVIELCVALFGALSLLSAFSPDIETLVLLRFLTGLGLG 125 Query: 128 GALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGAL 187 GA+PN + + SEY P R +V + CG LG+ +GGIV++ L+P GWH + +GG L Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAMGGIVSAQLVPLIGWHGILALGGIL 185 Query: 188 PIAVALFALAF-MPESARFLLVRGKHRARLQALMRRIAPELGADQD--LAAPPPQAPGVP 244 P+ + F L F +PES R+ + R +A + + I E D L A G Sbjct: 186 PLML-FFGLLFALPESPRWQVRRQLPQAVVARTVSAITGERYHDTQFFLHETAAVAKG-S 243 Query: 245 VAELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGGV 304 + +LF + T++LW+ +FM+L+++Y + SWMP +L + + F GG Sbjct: 244 IRQLFAGRQLVITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQQASWVTAAFQVGGT 303 Query: 305 LGSLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQGAQAG 364 LG+LL G LM+ L R L + AL A+ + + W + + G+ I G+Q G Sbjct: 304 LGALLLGVLMDRLNPFRVLAVSYALGAVCIVMIGLSENGLWLMALAIFGTGIGISGSQVG 363 Query: 365 LNVLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIA 424 LN L +YPT RATGV ++ IGR G+I G L+G +M+ +F + PA I+ Sbjct: 364 LNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGMMMALNFSFDTLFFVIAIPAAIS 423 Query: 425 AL 426 A+ Sbjct: 424 AV 425 >PA2472 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 227 bits (579), Expect = 4e-59, Method: Compositional matrix adjust. Identities = 171/440 (38%), Positives = 250/440 (56%), Gaps = 5/440 (1%) Query: 2 QSATPIQVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASF 61 I V IDA+ V Q + C LI +DGFDT IG +APA++ + + A Sbjct: 5 DKNNKIDVQAFIDAQAVSAFQLRVLSLCFLIVAMDGFDTAAIGFIAPALAHDWQLSPAQL 64 Query: 62 GPIFSAGLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFL 121 PI A L G+ +GA GPLADRFGRK++++ + L FG SL +A A + + L LLRF Sbjct: 65 SPILGAALAGLALGAFAAGPLADRFGRKSVLLLSVLFFGGWSLASAYAGSVETLALLRFF 124 Query: 122 TGIGLGGALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVF 181 TG+GLGGA+PNA+ L SEY PRRH ++V + CG LG+ LGG++ + ++P+ GW +V Sbjct: 125 TGLGLGGAMPNAITLTSEYCPRRHRALMVTAMFCGFTLGSALGGLLAARMVPALGWESVL 184 Query: 182 IVGGALPIAVALFALAFMPESARFLLVRGKHRARLQALMRRIA--PELGADQDLAAPPPQ 239 ++GG LP+A A +PES RFL R ARL+ ++ R+ P+ G L P + Sbjct: 185 LLGGGLPLASLPLLWACLPESVRFLARRAPDAARLRRILERLGRLPD-GWAGRLELPADE 243 Query: 240 APGV-PVAELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISC 298 + G P+ ++ T+LLW +FM L+++Y + +W+P ++ G + T + Sbjct: 244 SDGTSPLRQILGAELRGGTLLLWATFFMGLLIIYLLTNWLPTLIGGTGFSLGEAATISAM 303 Query: 299 FSAGGVLGSLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVI 358 F GG LG+LL G M+ R L L AL L +A+ S + + + +G I Sbjct: 304 FQLGGTLGALLLGSAMDRFDAHRVLSLAYVGGALFILGIASLYHSFALLALCVAGVGFCI 363 Query: 359 QGAQAGLNVLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGI 418 G+Q G N LA + YPT RATGV +ALG+GRIGSI G L+G +LG + I + + Sbjct: 364 SGSQVGANALAADFYPTRSRATGVSWALGLGRIGSIVGSLSGGALLGLGLGFSGILALLV 423 Query: 419 TPAVIAALAI-VFNRRAETP 437 PA++AA+A+ RR P Sbjct: 424 IPALLAAVAVHRLGRRRARP 443 >PA4900 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 446 Score = 209 bits (533), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 145/422 (34%), Positives = 223/422 (52%), Gaps = 4/422 (0%) Query: 8 QVSEVIDARPVGMVQWSAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFSA 67 + VIDA W +G I + DG+D G + P + +E + G + S Sbjct: 5 SAAAVIDAARFNRTHWLILGWGCFIMLFDGYDMVIYGSVVPRLMQEWQLSPVQAGTLGSC 64 Query: 68 GLLGMLVGAMILGPLADRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGLG 127 L GML G +L PLADRFGR+ +VI TL + LT A +L RF TG+ LG Sbjct: 65 ALFGMLFGGTLLAPLADRFGRRRLVIATTLLASLAAFLTGHARDPLELGAGRFFTGLALG 124 Query: 128 GALPNALALASEYSPRRHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGAL 187 +P+A+ L SE++P +V + +GAVL ++ ++P+ GW +VF V L Sbjct: 125 ALVPSAINLISEFAPAGRRSTLVTVMSAFYSVGAVLSALLAIAMIPAWGWQSVFYV-AVL 183 Query: 188 PIAVALFALAFMPESARFLLVRGKHRARLQALMRRIAPELGADQDLA-APPPQAPGVPVA 246 P+ L ++PESA FL ++G+ RA L AL+R++ P+ + A A +AP VA Sbjct: 184 PVLAVPLMLRWLPESAAFLELKGR-RAELDALLRKVDPDYRPGAERANAVAAEAPSGRVA 242 Query: 247 ELFRQGRWKDTVLLWIPYFMNLVVLYFIVSWMPAVLMGAHHPVSVGITAISCFSAGGVLG 306 +LF + T+LLW+ + M +++ Y + +W+P ++ G + + + + + G LG Sbjct: 243 QLFEGRQAVGTLLLWVAFAMCMLMSYGLNTWLPKLMAGGGYALGSSLAFLVTLNVGATLG 302 Query: 307 SLLQGWLMNALGVRRTLVLELALYALLALALATWPQSEWNVMVVSSLMGVVIQGAQAGLN 366 +L GWL + LG RTLVL AL A AL P W + + + G G A ++ Sbjct: 303 ALFGGWLADRLGAGRTLVLFFALAAASLAALGLGP-GPWLLNGLLVVAGATTIGTLAVIH 361 Query: 367 VLATEIYPTAMRATGVGFALGIGRIGSICGPLAGSLMLGWQMDVKHIFLMGITPAVIAAL 426 A + YP +R+TGVG+A G+GR+G+I GP+ G +L ++ + FL P VI AL Sbjct: 362 AYAAQFYPAWVRSTGVGWAAGVGRLGAIAGPMLGGSLLALELPFQQNFLAFAAPGVIGAL 421 Query: 427 AI 428 AI Sbjct: 422 AI 423 >RSp1595 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 424 Score = 187 bits (475), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 147/384 (38%), Positives = 202/384 (52%), Gaps = 32/384 (8%) Query: 24 SAIGTCILIAVLDGFDTQTIGMLAPAMSRELGIPMASFGPIFSAGLLGMLVGAMILGPLA 83 + +G C ++A+L+G D Q+IG+ AP M+RE G+ + G FSAG G+L GAM+ G LA Sbjct: 34 TTLGLCFIVALLEGLDLQSIGVAAPRMAREFGLSVGQMGLAFSAGTFGLLPGAMLGGRLA 93 Query: 84 DRFGRKTMVITATLAFGSMSLLTAAAATHDDLLLLRFLTGIGLGGALPNALALASEYSPR 143 DR GRK ++I AT FG S+ TA LL++R TGIGLGGA+PN +AL +E P Sbjct: 94 DRIGRKRVLILATALFGVFSIATAQVWDFASLLVIRVATGIGLGGAMPNLIALCAEAVPP 153 Query: 144 RHARVIVATLMCGMPLGAVLGGIVTSLLLPSHGWHAVFIVGGALPIAVALFALAFMPESA 203 R V+ + CG+P G + +V L GW +F VGG + + L + ES Sbjct: 154 RLRNTAVSVMYCGIPFGGAIAAVVGLLSAGDTGWRHIFYVGG-FGPLLVVPLLLTLRESR 212 Query: 204 RFLLVRGKHRARLQALMRRIAPELGADQDLAAPPPQAPGVPVAELFRQGRWKDTVLLWIP 263 RF R A D PPP A LF + R T LWI Sbjct: 213 RF---------------ERTAQ---GDGGTVQPPPVA-----WALFGERRAAATAWLWIS 249 Query: 264 YFMNLVVLYFIVSWMPAVL--MGAHHPVSVGITAISCFSAGGVLGSLLQGWLMNALGVRR 321 YF L+VLYF+++W+P++ G P VG+ I F+ GG G+L G LM+A R Sbjct: 250 YFFTLIVLYFLLNWLPSLTAAQGLTRP-QVGLVQI-LFNIGGGAGALGIGMLMDA--ARP 305 Query: 322 TLVLELALYALLALALATWPQSEWNVMVVSSLM-GVVIQGAQAGLNVLATEIYPTAMRAT 380 LV+ ++A M + M G+ + GAQ+ L LA YPT++R T Sbjct: 306 RLVVSGMYVGIIAALALLAAAGGMASMSAGAFMAGLFVVGAQSVLYALAAAYYPTSVRGT 365 Query: 381 GVGFALGIGRIGSICGP-LAGSLM 403 GVG A+ +GR+GSI GP LAG L+ Sbjct: 366 GVGAAVAVGRLGSIAGPLLAGQLL 389