BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0088.p (477 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl2660 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Ag... 722 0.0 BMEII0225 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme ... 575 e-163 SMb20378 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme S... 488 e-138 BMEII0869 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme ... 474 e-133 mll1168 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Me... 407 e-113 PA0265 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 401 e-111 BH0995 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bac... 394 e-109 BS_ycnH [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Ba... 385 e-106 ZgabD [C] COG1012 NAD-dependent aldehyde dehydrogenases EcZ Esch... 383 e-106 ECs3522 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ecs Es... 383 e-106 >AGl2660 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 483 Score = 722 bits (1864), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/474 (70%), Positives = 407/474 (85%) Query: 2 YKDVQLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNM 61 Y D++L I+GEW + SG+TI V +PAT+E+IG IAHA++ DLD AL AA +GF+ WR+ Sbjct: 9 YPDIKLLIDGEWRDAVSGKTIAVSDPATDEIIGAIAHAEKEDLDLALAAAERGFKLWRDT 68 Query: 62 SAFERSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTY 121 S +ERSKIMR+AAD+LRER +++A +MT EQGKPLA++ E +GAADTIDWFAEEARRTY Sbjct: 69 SPYERSKIMRKAADILRERKDKIAYIMTREQGKPLAQSATEIMGAADTIDWFAEEARRTY 128 Query: 122 GRLGPARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPA 181 G++ PAR G Q+ IK PVGPVAAFTPWNFPLNQ+VRKLSAALA GCSIIVKAPEETPA Sbjct: 129 GQVIPARATGVSQLAIKVPVGPVAAFTPWNFPLNQIVRKLSAALATGCSIIVKAPEETPA 188 Query: 182 SPAELIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQ 241 SPAELIRA+ DAGVPAGVI LVYGVP+EISEYLIPHPVI+KISFTGSTP+GK LAALAG+ Sbjct: 189 SPAELIRAFVDAGVPAGVIGLVYGVPSEISEYLIPHPVIRKISFTGSTPIGKHLAALAGK 248 Query: 242 HMKRATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVD 301 HMKRATMELGGHAP M+FDDAD++ A ++ + AKFRNAGQVCV+PTRFLVQ GV + F++ Sbjct: 249 HMKRATMELGGHAPVMIFDDADIEKAIEVTSLAKFRNAGQVCVAPTRFLVQDGVADRFLE 308 Query: 302 KFVTYAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYF 361 FV + +KVGNGLE G+ MGP+AN+RRIPALE LI+DAVS GA+L+TGG+RIGNKG F Sbjct: 309 GFVEATKAIKVGNGLEEGVIMGPLANERRIPALEGLINDAVSHGAELKTGGRRIGNKGNF 368 Query: 362 FQPTVLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKH 421 F+PTVL N+P+ A+ MN+EPFGP+A+IN F + D+ ITEANRLP+GLA+YAF S T H Sbjct: 369 FEPTVLANVPVTAKIMNDEPFGPVAIINRFSSFDDAITEANRLPFGLASYAFTGSVKTAH 428 Query: 422 ALAARVESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVTQL 475 AL +VE+GMLTINH GLALPE+PFGGIKDSGYG+EGG+EA++AY+ TK V+Q+ Sbjct: 429 ALGQQVEAGMLTINHNGLALPEVPFGGIKDSGYGTEGGSEAVQAYLETKFVSQM 482 >BMEII0225 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme Brucella melitensis Length = 473 Score = 575 bits (1481), Expect = e-163, Method: Compositional matrix adjust. Identities = 278/436 (63%), Positives = 343/436 (78%) Query: 2 YKDVQLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNM 61 Y DV+LFI+G W + G TI++ NPAT+EVIG IA A ADLD AL A +GFE W + Sbjct: 12 YPDVKLFIDGTWRDGSRGETIEIFNPATDEVIGHIARATTADLDDALAAVDRGFEAWSKV 71 Query: 62 SAFERSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTY 121 SAF+R KIMRRAAD+ R R EEVARL+TMEQGKPLAEA++E A D IDWFAEEARR+Y Sbjct: 72 SAFDRYKIMRRAADIFRSRGEEVARLLTMEQGKPLAEARIEAAAACDLIDWFAEEARRSY 131 Query: 122 GRLGPARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPA 181 GR+ P R Q +KEPVGPVAAFTPWNFP+NQ VRK+SAALAAGCSI++KA E+TPA Sbjct: 132 GRIVPPRQAYVMQAEVKEPVGPVAAFTPWNFPINQAVRKISAALAAGCSILLKAAEDTPA 191 Query: 182 SPAELIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQ 241 +PAEL+RA+A+AG+P G INLVYG PAEIS YLIPHPVI+K+SFTGST VGKQLAALAG Sbjct: 192 APAELVRAFAEAGLPDGAINLVYGDPAEISAYLIPHPVIRKVSFTGSTQVGKQLAALAGL 251 Query: 242 HMKRATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVD 301 HMKR TMELGGHAP ++ DADV+ A K+++ +KFRNAGQVC+SPTRFL++ V++ V+ Sbjct: 252 HMKRVTMELGGHAPVIIAADADVEQAIKVVSGSKFRNAGQVCISPTRFLIENSVYDQVVE 311 Query: 302 KFVTYAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYF 361 YA LKVG+GLEAG TMGP+ N +R+ A+E L+ DA A++ TGG+RIGN+G F Sbjct: 312 GMAAYATSLKVGDGLEAGTTMGPLVNAKRVNAMERLVQDAREHKARVVTGGERIGNRGNF 371 Query: 362 FQPTVLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKH 421 F+PT+L ++P A MNEEPFGP+AL+N F+ LDE ++EANRL YGLAAYAF S+ Sbjct: 372 FEPTILADVPRDAAIMNEEPFGPVALLNRFDALDEALSEANRLNYGLAAYAFTGSSAKAA 431 Query: 422 ALAARVESGMLTINHL 437 +++ V SGM+TIN L Sbjct: 432 RISSTVRSGMITINQL 447 >SMb20378 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 487 Score = 488 bits (1257), Expect = e-138, Method: Compositional matrix adjust. Identities = 241/475 (50%), Positives = 331/475 (69%), Gaps = 1/475 (0%) Query: 2 YKDVQLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNM 61 Y+ + + I+G W A R+ +V++PAT + I ++ A ++ A+ ++ + FE+W++ Sbjct: 10 YERLGILIDGRWIYEAE-RSTEVVDPATGQTIARLPFAADGEIAEAVASSQRAFESWKDR 68 Query: 62 SAFERSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTY 121 S ER +I+RR ADL R+ A+E+AR MT +QGKPL+EA E AAD DW AEEARR Y Sbjct: 69 SPLERGRILRRFADLARKHADEIARNMTRDQGKPLSEAIGEIRFAADHADWHAEEARRIY 128 Query: 122 GRLGPARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPA 181 GR+ PAR P QMV++EPVG AFTPWNFP +Q +RK+ AALA+GC+II+K P E+P+ Sbjct: 129 GRVIPARDPRVQQMVLREPVGVCIAFTPWNFPFSQALRKVVAALASGCTIILKGPGESPS 188 Query: 182 SPAELIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQ 241 S + R +AG+P G +N+++G PA +SE L+ P ++KISFTGS VGK LA+LAG+ Sbjct: 189 STVAIGRLMQEAGLPDGCLNILWGDPAHLSETLLAAPEVRKISFTGSVEVGKHLASLAGR 248 Query: 242 HMKRATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVD 301 HMKR+TMELGGHAP ++FDDAD++ AA LA K RNAGQVC+SPTRF VQ + F+ Sbjct: 249 HMKRSTMELGGHAPVILFDDADIEAAADALAGQKVRNAGQVCISPTRFYVQAKGHDRFLA 308 Query: 302 KFVTYAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYF 361 +F +VGNG + + MGP+ + RR+ A+E I DA QGA++ TGG+R+GN G+F Sbjct: 309 RFAEKIASTRVGNGFQESVQMGPLCHGRRVAAMEGFIQDAREQGAEIVTGGERVGNAGFF 368 Query: 362 FQPTVLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKH 421 + PTV+ + R M EEPFGP+A++ F DEVI AN LP+GLA+Y F S+ Sbjct: 369 YAPTVVAAGTDELRLMKEEPFGPIAVVTPFGDFDEVIRRANSLPFGLASYVFTGSSSRAQ 428 Query: 422 ALAARVESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVTQLD 476 A + +GM+++NH GLALPE PFGGI DSGYGSEGG+E + Y+NTK VT+ D Sbjct: 429 NAARALAAGMVSVNHFGLALPETPFGGINDSGYGSEGGSETFDGYLNTKFVTRFD 483 >BMEII0869 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme Brucella melitensis Length = 483 Score = 474 bits (1221), Expect = e-133, Method: Compositional matrix adjust. Identities = 227/467 (48%), Positives = 324/467 (69%), Gaps = 1/467 (0%) Query: 1 MYKDVQLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRN 60 MY ++ L + GE S T+ + +PA + A RA+ +A AA KGF W Sbjct: 8 MYPNLTLIVGGEERNKGSAGTLCLTDPADGRELTIAPRAGRAEALQA-AAAEKGFAEWSA 66 Query: 61 MSAFERSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRT 120 +SA ERSKIMRRAAD++RERA+ AR+M+MEQGKPL+EA+ E LG+AD +DWFAEE RR Sbjct: 67 LSALERSKIMRRAADIMRERADAAARIMSMEQGKPLSEARGEWLGSADLLDWFAEEGRRV 126 Query: 121 YGRLGPARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETP 180 YGR+ P+R P V+K P+GPVAAFTPWNFP ++K++ AL AGCS+++K +TP Sbjct: 127 YGRIVPSRAPNIQIQVLKHPIGPVAAFTPWNFPAWNTMQKVAPALGAGCSVVIKPASDTP 186 Query: 181 ASPAELIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAG 240 + + + +AG+P +++++G +E+S+ LI P I+K+S TGST VG+ +AA AG Sbjct: 187 GTAWLIGKCLLEAGLPPKAVSVIWGTTSELSDALIKAPEIRKVSLTGSTRVGRIVAAQAG 246 Query: 241 QHMKRATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFV 300 +++K+ TMELGGH P +V DAD+D + KFRN GQVCVSPTRF+V+ + + F+ Sbjct: 247 EYLKKVTMELGGHGPVIVAADADLDHLIPLAVQWKFRNCGQVCVSPTRFIVEASIHDEFI 306 Query: 301 DKFVTYAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGY 360 +F A +LKVG G+E G MGP+ ++ ++ + ++++DA+++GA++ TGG RIG+ G Sbjct: 307 RRFSEKARELKVGKGVEEGAQMGPLTSQNQLETVLSMVEDALTKGAKIETGGNRIGDTGN 366 Query: 361 FFQPTVLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTK 420 F++PT+L+ + + AMNEEPFGPLAL+ +LDE I E+NRLP GL AY F S T Sbjct: 367 FYEPTILSGMTAEMLAMNEEPFGPLALVMRVHSLDEAIAESNRLPVGLGAYLFTSSMTTA 426 Query: 421 HALAARVESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYI 467 H + +++GML +NH LALPE PFGG++DSG+GSEGG E IEAY+ Sbjct: 427 HRVQNHLQAGMLGVNHFALALPETPFGGVRDSGFGSEGGLEGIEAYL 473 >mll1168 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Mesorhizobium loti Length = 485 Score = 407 bits (1047), Expect = e-113, Method: Compositional matrix adjust. Identities = 210/466 (45%), Positives = 292/466 (62%) Query: 8 FINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNMSAFERS 67 INGEW + SG+T+DV NPAT IG + + +A+ RA+EAA F+TWR +A ERS Sbjct: 14 LINGEWVQADSGQTVDVNNPATGLKIGTVPKSGKAETRRAIEAADAAFKTWRKTTALERS 73 Query: 68 KIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTYGRLGPA 127 K++R+ D + + + +A L+T+EQGK L E+K E AA I WFAEE RRTYG + P+ Sbjct: 74 KLLRKLHDAMMDNQDVLAELLTIEQGKSLFESKGEIGSAAAYILWFAEEGRRTYGDVVPS 133 Query: 128 RVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPASPAELI 187 +V KEPVG +AA TPWNFP + + RKL ALAAGC+ +VK +TP S Sbjct: 134 PWADRRILVTKEPVGVIAAITPWNFPSSMLARKLGPALAAGCTAVVKPASQTPYSGLAWG 193 Query: 188 RAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQHMKRAT 247 + G P GV+N++ G +EI + + +P++ KI+FTGST VGK L + +K+ + Sbjct: 194 ALAEEVGFPKGVVNILTGSASEIGDEICANPLVSKITFTGSTEVGKLLIQKSSVTVKKVS 253 Query: 248 MELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVDKFVTYA 307 MELGG+AP +VFDDAD++ A TAK+RN+GQ CV RFLVQ GV++ FV+K + Sbjct: 254 MELGGNAPFIVFDDADIERAVAGAITAKYRNSGQTCVCTNRFLVQAGVYDKFVEKLAAAS 313 Query: 308 EQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYFFQPTVL 367 LKVG+GLE G+ GP+ +++ + +E LI DA S+G ++ GGKR G FFQPTV+ Sbjct: 314 NGLKVGSGLEEGVQQGPLIDEKAVEKVEELIADATSKGGKIVAGGKRHALGGSFFQPTVI 373 Query: 368 TNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKHALAARV 427 N + R M EE FGP+A + FET E I AN +GLA Y + + + Sbjct: 374 ANATPKMRFMKEEIFGPVAPVFKFETEAEAIALANDTEFGLACYFYTGDLGRAFRVMEGL 433 Query: 428 ESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVT 473 + GM+ +N + PE PFGG+K+SG G EGG + IE Y++TK V Sbjct: 434 KYGMVGVNEGLITTPEAPFGGVKESGLGKEGGHQGIEDYLDTKYVC 479 >PA0265 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 483 Score = 401 bits (1031), Expect = e-111, Method: Compositional matrix adjust. Identities = 208/469 (44%), Positives = 294/469 (62%), Gaps = 2/469 (0%) Query: 6 QLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNMSAFE 65 Q +++G W + +G+TI V NPAT E+IG + A+ RA+EAA K WR ++A E Sbjct: 12 QAYVDGAWVDADNGQTIKVNNPATGEIIGSVPKMGAAETRRAIEAADKALPAWRALTAKE 71 Query: 66 RSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTYGRLG 125 R+ +RR DL+ E +++ARLMT+EQGKPLAEAK E AA ++WF EEA+R YG Sbjct: 72 RANKLRRWFDLMIENQDDLARLMTIEQGKPLAEAKGEIAYAASFLEWFGEEAKRIYGDTI 131 Query: 126 PARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPASPAE 185 P P +VIK+P+G AA TPWNFP + RK ALAAGC++++K +TP S Sbjct: 132 PGHQPDKRIIVIKQPIGVTAAITPWNFPSAMITRKAGPALAAGCTMVLKPASQTPYSALA 191 Query: 186 LIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQHMKR 245 L AG+P GV ++V G E+ L +P+++K++FTGST +G+QL A Q +K+ Sbjct: 192 LAELAERAGIPKGVFSVVTGSAGEVGGELTSNPIVRKLTFTGSTEIGRQLMAECAQDIKK 251 Query: 246 ATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVDKFVT 305 ++ELGG+AP +VFDDAD+D A + +K+RN GQ CV R VQ GV++AFVDK Sbjct: 252 VSLELGGNAPFIVFDDADLDAAVEGALISKYRNNGQTCVCANRLYVQDGVYDAFVDKLKA 311 Query: 306 YAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYFFQPT 365 +L +GNGLEAG+T GP+ + + + +E I DAVS+GA++ +GGK G FF+PT Sbjct: 312 AVAKLNIGNGLEAGVTTGPLIDAKAVAKVEEHIADAVSKGAKVVSGGKPHALGGTFFEPT 371 Query: 366 VLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKHALAA 425 +L ++P A +E FGPLA + F+ EVI +N +GLA+Y +A+ +A Sbjct: 372 ILVDVPKNALVSKDETFGPLAPVFRFKDEAEVIAMSNDTEFGLASYFYARDLARVFRVAE 431 Query: 426 RVESGMLTINHLGLALPEL-PFGGIKDSGYGSEGGTEAIEAYINTKLVT 473 ++E GM+ IN GL E+ PFGGIK SG G EG IE Y+ K + Sbjct: 432 QLEYGMVGINT-GLISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYLC 479 >BH0995 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bacillus halodurans Length = 468 Score = 394 bits (1013), Expect = e-109, Method: Compositional matrix adjust. Identities = 204/469 (43%), Positives = 294/469 (62%), Gaps = 5/469 (1%) Query: 5 VQLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNMSAF 64 + L+INGEW S G+T+DV NPAT EVI + A + + + A+ AA + F W + +A Sbjct: 1 MDLYINGEWMRS--GKTLDVTNPATGEVIDTVPFAGKKEAELAVSAAYEAFPQWSSQTAS 58 Query: 65 ERSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTYGRL 124 ERS+ + R L+ E+ +E+ +MT EQGKPL EA E A I W+AEEA+R YG Sbjct: 59 ERSRYLMRWFQLIDEQQDEIGEIMTKEQGKPLREAIGEVQYANSFIQWYAEEAKRIYGDT 118 Query: 125 GPARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPASPA 184 PA +V K+PVG +AA TPWNFP + RK++ ALAAGC+ IVK E+TP + Sbjct: 119 IPASAINKRILVQKQPVGVIAAITPWNFPAAMITRKVAPALAAGCTAIVKPAEQTPLTAL 178 Query: 185 ELIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQHMK 244 +L + +AG+PAGV+N++ G +I E + ++KI+FTGST VGK L A Q +K Sbjct: 179 KLAQLAEEAGIPAGVLNVITGNAQDIGEAWLEDSRVRKITFTGSTEVGKLLMRGAAQTVK 238 Query: 245 RATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVDKFV 304 + ++ELGGHAP ++ DDA+++ A + +KFRNAGQ CV R V + + AF +KF Sbjct: 239 KISLELGGHAPFIIMDDANLEEAVDQVIASKFRNAGQTCVCANRIYVAREIAEAFTEKFA 298 Query: 305 TYAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYFFQP 364 +LKVGNGLE G+T+GP+ +K + +EA I DA+ +G Q+ GG+ +FF+P Sbjct: 299 AKVNELKVGNGLEEGVTIGPLIDKAAVEKVEAHIHDALKKGGQVTVGGRWT---NHFFEP 355 Query: 365 TVLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKHALA 424 T++T + MNEE FGPLA + +F+T +EVI AN PYGLAAY F ++ L+ Sbjct: 356 TIITGATDEMLCMNEETFGPLAPVATFDTEEEVIERANHTPYGLAAYVFTENIGRAIRLS 415 Query: 425 ARVESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVT 473 ++E G++ +N ++ + PFGG K+SG G EGG IE Y+ K V+ Sbjct: 416 EKLEYGIVGVNDGMPSVAQAPFGGWKESGLGREGGKYGIEEYLEVKYVS 464 >BS_ycnH [C] COG1012 NAD-dependent aldehyde dehydrogenases Bsu Bacillus subtilis Length = 462 Score = 385 bits (990), Expect = e-106, Method: Compositional matrix adjust. Identities = 202/455 (44%), Positives = 280/455 (61%), Gaps = 3/455 (0%) Query: 22 IDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNMSAFERSKIMRRAADLLRERA 81 + V NPAT E I I +++ A+E + + F+TW SA ER+ ++++ +L+ E Sbjct: 5 LTVYNPATGEEIKTIPQQSATEVEEAIERSHQAFKTWSKTSANERTSLLKKWYELIVEHK 64 Query: 82 EEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTYGRLGPARVPGAYQMVIKEPV 141 EE+A L+T E GKP EA E L A I+WFAEEA+R YGR PA G +V ++PV Sbjct: 65 EELADLITKENGKPYQEAVGEVLYGAGYIEWFAEEAKRVYGRTVPAPTTGKRIVVTRQPV 124 Query: 142 GPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPASPAELIRAYADAGVPAGVIN 201 GPVAA TPWNFP + RK + ALAAGC+ I+K +TP S EL R +AG+P V+ Sbjct: 125 GPVAAITPWNFPNAMITRKAAPALAAGCTFIIKPAPDTPLSAYELARLAYEAGIPKDVLQ 184 Query: 202 LVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQHMKRATMELGGHAPAMVFDD 261 +V G EI P I+KI+FTGSTPVGK L + +K +MELGGHAP +V +D Sbjct: 185 VVIGDGEEIGNVFTSSPKIRKITFTGSTPVGKILMKNSADTVKHVSMELGGHAPLIVDED 244 Query: 262 ADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVDKFVTYAEQLKVGNGLEAGIT 321 AD+D+A + +K+RNAGQ CV R +V + + + F K +LKVGNGLE G+ Sbjct: 245 ADIDLAVEQAMASKYRNAGQTCVCANRLIVHESIKDEFAAKLSEQVSKLKVGNGLEEGVN 304 Query: 322 MGPVANKRRIPALEALIDDAVSQGAQLRTGG--KRIGNKG-YFFQPTVLTNLPLQARAMN 378 +GP+ NKR + + IDDAV +GA++ GG R +KG YF PTVLT++ M+ Sbjct: 305 VGPIINKRGFEKIVSQIDDAVEKGAKVIAGGTYDRNDDKGCYFVNPTVLTDVDTSMNIMH 364 Query: 379 EEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKHALAARVESGMLTINHLG 438 EE FGP+A I +F +DE I AN PYGLAAY F ++ ++ +E G++ N G Sbjct: 365 EETFGPVAPIVTFSDIDEAIQLANDTPYGLAAYFFTENYRRGIYISENLEYGIIGWNDGG 424 Query: 439 LALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVT 473 + + PFGG+K+SG G EGG+E IE Y+ TK ++ Sbjct: 425 PSAVQAPFGGMKESGIGREGGSEGIEPYLETKYLS 459 >ZgabD [C] COG1012 NAD-dependent aldehyde dehydrogenases EcZ Escherichia coli O157:H7 EDL933 Length = 482 Score = 383 bits (983), Expect = e-106, Method: Compositional matrix adjust. Identities = 195/468 (41%), Positives = 284/468 (60%) Query: 6 QLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNMSAFE 65 Q INGEW + +G IDV NPA + +G + + A++AA++ WR ++A E Sbjct: 12 QALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPVWRALTAKE 71 Query: 66 RSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTYGRLG 125 R+ I+R +L+ E +++ARLMT+EQGKPLAEAK E AA I+WFAEE +R YG Sbjct: 72 RANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTI 131 Query: 126 PARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPASPAE 185 P +VIK+P+G AA TPWNFP + RK ALAAGC++++K +TP S Sbjct: 132 PGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALA 191 Query: 186 LIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQHMKR 245 L AG+PAGV N+V G + L +P+++K+SFTGST +G+QL + +K+ Sbjct: 192 LAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKK 251 Query: 246 ATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVDKFVT 305 ++ELGG+AP +VFDDAD+D A + +KFRNAGQ CV R VQ GV++ F +K Sbjct: 252 VSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQ 311 Query: 306 YAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYFFQPT 365 +L +G+GL+ G+T+GP+ +++ + +E I DA+ +GA++ GGK G FFQPT Sbjct: 312 AVSKLHIGDGLDKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPT 371 Query: 366 VLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKHALAA 425 +L ++P A+ EE FGPLA + F+ +VI +AN +GLAAY +A+ + Sbjct: 372 ILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGE 431 Query: 426 RVESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVT 473 +E G++ IN ++ PFGGIK SG G EG IE Y+ K + Sbjct: 432 ALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMC 479 >ECs3522 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ecs Escherichia coli O157:H7 Length = 482 Score = 383 bits (983), Expect = e-106, Method: Compositional matrix adjust. Identities = 195/468 (41%), Positives = 284/468 (60%) Query: 6 QLFINGEWTASASGRTIDVINPATEEVIGKIAHADRADLDRALEAASKGFETWRNMSAFE 65 Q INGEW + +G IDV NPA + +G + + A++AA++ WR ++A E Sbjct: 12 QALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPVWRALTAKE 71 Query: 66 RSKIMRRAADLLRERAEEVARLMTMEQGKPLAEAKMETLGAADTIDWFAEEARRTYGRLG 125 R+ I+R +L+ E +++ARLMT+EQGKPLAEAK E AA I+WFAEE +R YG Sbjct: 72 RANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTI 131 Query: 126 PARVPGAYQMVIKEPVGPVAAFTPWNFPLNQVVRKLSAALAAGCSIIVKAPEETPASPAE 185 P +VIK+P+G AA TPWNFP + RK ALAAGC++++K +TP S Sbjct: 132 PGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALA 191 Query: 186 LIRAYADAGVPAGVINLVYGVPAEISEYLIPHPVIKKISFTGSTPVGKQLAALAGQHMKR 245 L AG+PAGV N+V G + L +P+++K+SFTGST +G+QL + +K+ Sbjct: 192 LAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKK 251 Query: 246 ATMELGGHAPAMVFDDADVDVAAKMLATAKFRNAGQVCVSPTRFLVQKGVFNAFVDKFVT 305 ++ELGG+AP +VFDDAD+D A + +KFRNAGQ CV R VQ GV++ F +K Sbjct: 252 VSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQ 311 Query: 306 YAEQLKVGNGLEAGITMGPVANKRRIPALEALIDDAVSQGAQLRTGGKRIGNKGYFFQPT 365 +L +G+GL+ G+T+GP+ +++ + +E I DA+ +GA++ GGK G FFQPT Sbjct: 312 AVSKLHIGDGLDKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPT 371 Query: 366 VLTNLPLQARAMNEEPFGPLALINSFETLDEVITEANRLPYGLAAYAFAKSAHTKHALAA 425 +L ++P A+ EE FGPLA + F+ +VI +AN +GLAAY +A+ + Sbjct: 372 ILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGE 431 Query: 426 RVESGMLTINHLGLALPELPFGGIKDSGYGSEGGTEAIEAYINTKLVT 473 +E G++ IN ++ PFGGIK SG G EG IE Y+ K + Sbjct: 432 ALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMC 479