BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0084.p (189 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0666 [L] COG2818 3-methyladenine DNA glycosylase Rso Ralstoni... 211 6e-55 VC1672 [L] COG2818 3-methyladenine DNA glycosylase Vch Vibrio ch... 202 3e-52 Ztag [L] COG2818 3-methyladenine DNA glycosylase EcZ Escherichia... 200 1e-51 ECs4434 [L] COG2818 3-methyladenine DNA glycosylase Ecs Escheric... 200 1e-51 STM3642 [L] COG2818 3-methyladenine DNA glycosylase Sty Salmonel... 199 4e-51 tag [L] COG2818 3-methyladenine DNA glycosylase Eco Escherichia ... 197 1e-50 YPO4074 [L] COG2818 3-methyladenine DNA glycosylase Ype Yersinia... 196 2e-50 lin1680 [L] COG2818 3-methyladenine DNA glycosylase Lin Listeria... 196 3e-50 L0289 [L] COG2818 3-methyladenine DNA glycosylase Lla Lactococcu... 192 3e-49 SP0180 [L] COG2818 3-methyladenine DNA glycosylase Spn Streptoco... 189 2e-48 >RSp0666 [L] COG2818 3-methyladenine DNA glycosylase Rso Ralstonia solanacearum Length = 190 Score = 211 bits (538), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 97/185 (52%), Positives = 129/185 (69%), Gaps = 1/185 (0%) Query: 5 LTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAA 64 ++RC W +P I YHD EWG P HD+ L+EML LEGAQAGLSW+T+L KR Y+ Sbjct: 1 MSRCCWVG-EDPLMIAYHDTEWGTPSHDDRHLYEMLVLEGAQAGLSWQTILRKRARYQEV 59 Query: 65 FDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAH 124 FDG+D ++AR+ ++ LLADPGIVRNR KV A + NAR L++++ +G LD +LWA Sbjct: 60 FDGFDPARVARFTPARIETLLADPGIVRNRAKVEAAVVNARKVLEVQDAVGSLDGFLWAF 119 Query: 125 VDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDC 184 V G+P+VNRW+S + PA T S A+SK LA RGFKFVG TI YA++Q G+++DH C Sbjct: 120 VGGRPVVNRWSSYRDAPASTEASKAMSKALAARGFKFVGPTICYAFMQATGMVDDHEAGC 179 Query: 185 HCHGR 189 G+ Sbjct: 180 FLAGK 184 >VC1672 [L] COG2818 3-methyladenine DNA glycosylase Vch Vibrio cholerae Length = 193 Score = 202 bits (514), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 96/180 (53%), Positives = 127/180 (70%), Gaps = 1/180 (0%) Query: 8 CGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAAFDG 67 C WA + +P +YHD EWG HD+T+LFE L LEGAQAGLSW TVL KRE YR AF G Sbjct: 9 CAWA-MNHPLEREYHDKEWGRAVHDDTKLFEFLTLEGAQAGLSWLTVLKKREGYRQAFLG 67 Query: 68 WDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAHVDG 127 +D +++A+ DE V Q++A+ +V++R K+A+ NARA L L++E G LDA LW V G Sbjct: 68 YDLQRLAQCDESHVEQIIAEYDVVKHRGKIASVFSNARAALALQQEFGSLDAALWQFVGG 127 Query: 128 QPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDCHCH 187 QP +NRW S+++ PA T S A+SK L +RGFKFVG TI YA++Q G++NDH+ C H Sbjct: 128 QPKINRWVSMSDVPASTEESKAMSKFLKKRGFKFVGETICYAFMQACGLVNDHLVGCPNH 187 >Ztag [L] COG2818 3-methyladenine DNA glycosylase EcZ Escherichia coli O157:H7 EDL933 Length = 187 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 94/183 (51%), Positives = 127/183 (69%), Gaps = 1/183 (0%) Query: 5 LTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAA 64 + RCGW + +P YI YHD+EWGVP D +LFEM+ LEG QAGLSW TVL KRE+YRA Sbjct: 1 MERCGWVS-QDPLYIAYHDNEWGVPETDRKKLFEMICLEGQQAGLSWITVLKKRENYRAC 59 Query: 65 FDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAH 124 F +D K+A E V +L+ D GI+R+R K+ A IGNARAYL++ + ++W+ Sbjct: 60 FHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFADFVWSF 119 Query: 125 VDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDC 184 V+ QP V + +L+E P TP SDA+SK L +RGFKFVG+TI Y+++Q G++NDHV C Sbjct: 120 VNHQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTTICYSFMQACGLVNDHVVGC 179 Query: 185 HCH 187 C+ Sbjct: 180 CCY 182 >ECs4434 [L] COG2818 3-methyladenine DNA glycosylase Ecs Escherichia coli O157:H7 Length = 187 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 94/183 (51%), Positives = 127/183 (69%), Gaps = 1/183 (0%) Query: 5 LTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAA 64 + RCGW + +P YI YHD+EWGVP D +LFEM+ LEG QAGLSW TVL KRE+YRA Sbjct: 1 MERCGWVS-QDPLYIAYHDNEWGVPETDRKKLFEMICLEGQQAGLSWITVLKKRENYRAC 59 Query: 65 FDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAH 124 F +D K+A E V +L+ D GI+R+R K+ A IGNARAYL++ + ++W+ Sbjct: 60 FHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFADFVWSF 119 Query: 125 VDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDC 184 V+ QP V + +L+E P TP SDA+SK L +RGFKFVG+TI Y+++Q G++NDHV C Sbjct: 120 VNHQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTTICYSFMQACGLVNDHVVGC 179 Query: 185 HCH 187 C+ Sbjct: 180 CCY 182 >STM3642 [L] COG2818 3-methyladenine DNA glycosylase Sty Salmonella typhimurium LT2 Length = 193 Score = 199 bits (505), Expect = 4e-51, Method: Compositional matrix adjust. Identities = 93/183 (50%), Positives = 124/183 (67%), Gaps = 1/183 (0%) Query: 5 LTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAA 64 + RC W + +P YI YHD+EWGVP D +LFEM+ LEG QAGLSW TVL KRE+YRA Sbjct: 1 MQRCDWVS-QDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRAC 59 Query: 65 FDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAH 124 F +D +IA E V LL + GI+R+R K+ A I NARA+L + + ++W+ Sbjct: 60 FHQFDPVRIAAMQEEDVEHLLQNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSF 119 Query: 125 VDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDC 184 VDGQP + + ASL E P TP SDA++K L +RGFKFVG+TI Y+++Q G++NDH+ C Sbjct: 120 VDGQPQITQAASLDEIPTSTPASDALAKALKKRGFKFVGTTICYSFMQACGLVNDHITGC 179 Query: 185 HCH 187 CH Sbjct: 180 FCH 182 >tag [L] COG2818 3-methyladenine DNA glycosylase Eco Escherichia coli K12 Length = 187 Score = 197 bits (501), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 93/183 (50%), Positives = 126/183 (68%), Gaps = 1/183 (0%) Query: 5 LTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAA 64 + RCGW + +P YI YHD+EWGVP D +LFEM+ LEG QAGLSW TVL KRE+YRA Sbjct: 1 MERCGWVS-QDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGLSWITVLKKRENYRAC 59 Query: 65 FDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAH 124 F +D K+A E V +L+ D GI+R+R K+ A IGNARAYL++ + ++W+ Sbjct: 60 FHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFVDFVWSF 119 Query: 125 VDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDC 184 V+ QP V + +L+E P T SDA+SK L +RGFKFVG+TI Y+++Q G++NDHV C Sbjct: 120 VNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTTICYSFMQACGLVNDHVVGC 179 Query: 185 HCH 187 C+ Sbjct: 180 CCY 182 >YPO4074 [L] COG2818 3-methyladenine DNA glycosylase Ype Yersinia pestis Length = 190 Score = 196 bits (499), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 92/184 (50%), Positives = 123/184 (66%), Gaps = 1/184 (0%) Query: 4 TLTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRA 63 +L RCGW ++P Y+ YHD EWGVP D LFEM+ LEG QAGLSW TVL KRE YR Sbjct: 2 SLQRCGWVT-SDPLYLAYHDTEWGVPLKDSRALFEMICLEGQQAGLSWITVLKKREHYRK 60 Query: 64 AFDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWA 123 +F +D K+A+ +V + D GI+R+R K+ A I NA+AYL + ++W+ Sbjct: 61 SFHHFDPVKVAKMGPEEVEIRVQDSGIIRHRGKIQAIITNAQAYLAMEANGEDFSRFIWS 120 Query: 124 HVDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQD 183 VD +P +N W LAE PA T +SDA+SK L +RGFKF+GSTI YA++Q G++NDH+ + Sbjct: 121 FVDDEPKINHWWCLAEAPATTAVSDAMSKALKKRGFKFIGSTICYAFMQASGLVNDHMAN 180 Query: 184 CHCH 187 C CH Sbjct: 181 CFCH 184 >lin1680 [L] COG2818 3-methyladenine DNA glycosylase Lin Listeria innocua Length = 193 Score = 196 bits (498), Expect = 3e-50, Method: Compositional matrix adjust. Identities = 92/187 (49%), Positives = 132/187 (70%), Gaps = 2/187 (1%) Query: 1 MTQTLTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRES 60 M++ L RC W+ + +P + YHD EW VP D+T LFEMLNLEGAQAGLSW+ +L+KR++ Sbjct: 1 MSEEL-RCPWS-INDPFELAYHDGEWCVPSKDDTYLFEMLNLEGAQAGLSWKLILHKRKA 58 Query: 61 YRAAFDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAY 120 Y+ AF +D +K AR + +A+++++ IV+NRLKV A NA A K++ E G Y Sbjct: 59 YQEAFFHFDIDKCARLTDEDLARIVSEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANY 118 Query: 121 LWAHVDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDH 180 +W+ +G+ I+N W + E PAKT LS+ ISKDL +RGFKFVG IIY+YLQ +G+++DH Sbjct: 119 IWSFTNGERIINEWQGMGEVPAKTELSEKISKDLKKRGFKFVGPVIIYSYLQAIGILDDH 178 Query: 181 VQDCHCH 187 ++ C H Sbjct: 179 LRSCPFH 185 >L0289 [L] COG2818 3-methyladenine DNA glycosylase Lla Lactococcus lactis Length = 190 Score = 192 bits (489), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 91/185 (49%), Positives = 126/185 (68%), Gaps = 2/185 (1%) Query: 1 MTQTLTRCGWANLANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRES 60 MT+ L RC W L+ + YHD WGVP H++ LF L L+ QAGLSW T+LNK+E+ Sbjct: 1 MTE-LRRCNWC-LSTDKMTHYHDTYWGVPLHNDQELFAKLVLDLNQAGLSWATILNKQEN 58 Query: 61 YRAAFDGWDAEKIARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAY 120 + AFD ++ EKIA YDE K +LL + GI+RN+LKV A I NA+ L++++E G + Y Sbjct: 59 FYEAFDNFEIEKIAVYDENKEQELLQNAGIIRNKLKVKAAIVNAQKVLEIQKEFGSFNKY 118 Query: 121 LWAHVDGQPIVNRWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDH 180 +W+ DG+ + ++ +E PA LSD +SKD+ +RGFKF GST+IYA+LQ VGVINDH Sbjct: 119 IWSFTDGKVLQHQVNDESEIPATNELSDKMSKDMKKRGFKFTGSTVIYAFLQAVGVINDH 178 Query: 181 VQDCH 185 C+ Sbjct: 179 ADYCY 183 >SP0180 [L] COG2818 3-methyladenine DNA glycosylase Spn Streptococcus pneumoniae TIGR4 Length = 178 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 83/176 (47%), Positives = 118/176 (67%) Query: 13 LANPRYIDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRESYRAAFDGWDAEK 72 + NP YI YHD EWG P HD+ LFE+L +E QAGLSWETVLNKR+++R F + Sbjct: 1 MTNPLYIAYHDEEWGQPLHDDQVLFELLCMETYQAGLSWETVLNKRQAFREVFHSYQIHS 60 Query: 73 IARYDERKVAQLLADPGIVRNRLKVAATIGNARAYLKLREEIGGLDAYLWAHVDGQPIVN 132 +A + ++ +L +P I+RNR K+ AT NA+A+L+L+ E G DAYLW+ V+G+ +VN Sbjct: 61 VAEMTDTELEAMLENPAIIRNRAKLFATRANAQAFLQLQAEYGSFDAYLWSFVEGKTVVN 120 Query: 133 RWASLAECPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVQDCHCHG 188 + PAKTPLS+ ++KDL +RGFKF G + ++LQ G+++DH DC G Sbjct: 121 DVPDYRQAPAKTPLSEKLAKDLKKRGFKFTGPVAVLSFLQAAGLVDDHENDCEWKG 176