BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0069.p (268 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2658 [R] COG0388 Predicted amidohydrolase Rso Ralstonia solan... 345 5e-95 NMA2044 [R] COG0388 Predicted amidohydrolase NmA Neisseria menin... 287 2e-77 NMB0441 [R] COG0388 Predicted amidohydrolase Nme Neisseria menin... 285 5e-77 PA4475 [R] COG0388 Predicted amidohydrolase Pae Pseudomonas aeru... 237 2e-62 VC0421 [R] COG0388 Predicted amidohydrolase Vch Vibrio cholerae 220 3e-57 alr2001 [R] COG0388 Predicted amidohydrolase Nos Nostoc sp. PCC ... 214 1e-55 sll0601 [R] COG0388 Predicted amidohydrolase Syn Synechocystis 203 4e-52 YPO3671 [R] COG0388 Predicted amidohydrolase Ype Yersinia pestis 194 1e-49 SMc02442 [R] COG0388 Predicted amidohydrolase Sme Sinorhizobium ... 191 2e-48 mll3450 [R] COG0388 Predicted amidohydrolase Mlo Mesorhizobium loti 188 1e-47 >RSc2658 [R] COG0388 Predicted amidohydrolase Rso Ralstonia solanacearum Length = 289 Score = 345 bits (885), Expect = 5e-95, Method: Compositional matrix adjust. Identities = 180/267 (67%), Positives = 210/267 (78%), Gaps = 3/267 (1%) Query: 5 IKVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADG 64 +VAAIQ V+ +V N A A L+A AA +GAQL LLPEY+ +MGR + DK+A EAD Sbjct: 23 FRVAAIQTVTGIDVDANLARADALLAEAAARGAQLALLPEYFCMMGRKDSDKVAIREADQ 82 Query: 65 VGPIQECMASLARQHGLWLVGGTLPLKADNPDKVLNTSLVYGPQGQRVARYDKIHLFNFV 124 GPIQ +A AR+H LWLVGGTLPL ++ ++V NTSL + P GQRVARYDKIHLFNFV Sbjct: 83 DGPIQAFLADAARRHRLWLVGGTLPLWCEDAERVRNTSLAFDPAGQRVARYDKIHLFNFV 142 Query: 125 RGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYRAM---GECALIVMPAAF 181 RGEE YDEARTIE G +FEAP GRVG+SVCYDLRFPELYRA+ G LI+MPAAF Sbjct: 143 RGEERYDEARTIEPGATPVAFEAPCGRVGMSVCYDLRFPELYRALSAQGNLNLILMPAAF 202 Query: 182 TYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEGE 241 TY TG AHWE+LLRARA+ENQCYVLA+AQGG H NGRRTWGHSMLVDPWGEI++ +PEGE Sbjct: 203 TYVTGAAHWEILLRARAVENQCYVLAAAQGGRHENGRRTWGHSMLVDPWGEIIASVPEGE 262 Query: 242 GLVIGDIDPHRLQYVRESLPALRHRKL 268 G+ IGD+DP RL VR LPAL+HR + Sbjct: 263 GVAIGDMDPARLAQVRRDLPALKHRVM 289 >NMA2044 [R] COG0388 Predicted amidohydrolase NmA Neisseria meningitidis Z2491 Length = 270 Score = 287 bits (734), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 145/264 (54%), Positives = 184/264 (69%) Query: 5 IKVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADG 64 I+VAA+QMVS N A+ RLVA AA+QG VLLPEYW +MG ++ DKLA AE G Sbjct: 4 IRVAAVQMVSGVSPETNVAAMKRLVARAAEQGVDWVLLPEYWVLMGANDTDKLALAEPLG 63 Query: 65 VGPIQECMASLARQHGLWLVGGTLPLKADNPDKVLNTSLVYGPQGQRVARYDKIHLFNFV 124 G Q ++ A++ G+ L GGT+PL++ KV+NT LVYG G+R Y K+HLF F Sbjct: 64 GGRFQTALSETAKECGVVLFGGTVPLQSPEAGKVMNTLLVYGRDGKRTGLYHKMHLFGFS 123 Query: 125 RGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYRAMGECALIVMPAAFTYT 184 E Y EA TI G EV A V +CYD+RFPE +R ++++PAAFT+T Sbjct: 124 GLGERYAEADTILAGREVPHLLAEGVSVAAGICYDVRFPEFFRRQLPFDVLMLPAAFTHT 183 Query: 185 TGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEGEGLV 244 TG+AHWELLLRARA+ENQCYV+A+AQGG H NGRRT+GHSM+VDPWG+++ VLPEGEG+V Sbjct: 184 TGKAHWELLLRARAVENQCYVVAAAQGGLHENGRRTFGHSMIVDPWGDVLDVLPEGEGIV 243 Query: 245 IGDIDPHRLQYVRESLPALRHRKL 268 DID +RL VR LPAL++R L Sbjct: 244 TADIDANRLNSVRNRLPALKYRVL 267 >NMB0441 [R] COG0388 Predicted amidohydrolase Nme Neisseria meningitidis MC58 Length = 270 Score = 285 bits (730), Expect = 5e-77, Method: Compositional matrix adjust. Identities = 145/264 (54%), Positives = 184/264 (69%) Query: 5 IKVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADG 64 I+VAA+QMVS N A+ RLVA AA+QGA VLLPEYW +MG ++ DKLA AE G Sbjct: 4 IRVAAVQMVSGVSPETNVAAMKRLVARAAEQGADWVLLPEYWVLMGANDTDKLALAEPLG 63 Query: 65 VGPIQECMASLARQHGLWLVGGTLPLKADNPDKVLNTSLVYGPQGQRVARYDKIHLFNFV 124 G Q ++ A++ G+ L GGT+PL++ KV+NT LVYG G R Y K+HLF F Sbjct: 64 GGRFQTALSETAKECGVVLFGGTVPLQSCEAGKVMNTLLVYGRDGVRTGLYHKMHLFGFS 123 Query: 125 RGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYRAMGECALIVMPAAFTYT 184 E Y EA TI G +V A V +CYD+RFPE +R ++++PAAFT+T Sbjct: 124 GLGERYAEADTIRAGGDVPHLSAEGVPVAAGICYDVRFPEFFRRQLPFDVLMLPAAFTHT 183 Query: 185 TGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEGEGLV 244 TG+AHWELLLRARA+ENQCYV+A+AQGG H NGRRT+GHSM+VDPWG+++ VLPEGEG+V Sbjct: 184 TGKAHWELLLRARAVENQCYVVAAAQGGLHENGRRTFGHSMIVDPWGDVLDVLPEGEGVV 243 Query: 245 IGDIDPHRLQYVRESLPALRHRKL 268 DID +RL VR LPAL++R L Sbjct: 244 TADIDANRLNSVRNRLPALKYRVL 267 >PA4475 [R] COG0388 Predicted amidohydrolase Pae Pseudomonas aeruginosa Length = 282 Score = 237 bits (605), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 127/272 (46%), Positives = 172/272 (63%), Gaps = 10/272 (3%) Query: 5 IKVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADG 64 + +A IQMVS +V N A+A RL+ AA+ GA+L +LPE + MGR + +L AEA G Sbjct: 1 MSIAVIQMVSQDDVTANLAAARRLLEQAAEGGARLAVLPENFAAMGRRDLAELGRAEARG 60 Query: 65 VGPIQECMASLARQHGLWLVGGTLPLKAD-NPDKVLNT-SLVYGPQGQRVARYDKIHLFN 122 GPI + S AR LW+V GTLPL D P+ N SL+ G+RVARYDK+HLF+ Sbjct: 61 NGPILPWLNSAARDLRLWIVAGTLPLPPDGQPEAKANACSLLIDEHGERVARYDKLHLFD 120 Query: 123 F----VRGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYRAMGECA--LIV 176 RG Y E+ +G ++ + P GR+GL+VCYDLRFPELY A+ E LI Sbjct: 121 VDVADARG--RYRESDDYAFGQKIVVADTPVGRLGLTVCYDLRFPELYTALREAGAELIT 178 Query: 177 MPAAFTYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSV 236 P+AFT TG AHW++L+RARAIE QCY+LA+ QGG H GR T+GHS +VDPWG +++ Sbjct: 179 APSAFTAVTGAAHWQVLVRARAIETQCYLLAAGQGGVHPRGRETFGHSAIVDPWGRVLAE 238 Query: 237 LPEGEGLVIGDIDPHRLQYVRESLPALRHRKL 268 P+GE +++ D +R +P + HR+ Sbjct: 239 RPQGEAVLLAVRDAAEQADIRRRMPVVAHRRF 270 >VC0421 [R] COG0388 Predicted amidohydrolase Vch Vibrio cholerae Length = 275 Score = 220 bits (560), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 115/268 (42%), Positives = 168/268 (62%), Gaps = 9/268 (3%) Query: 6 KVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADGV 65 +V +QM S PE++ N + VA AQQGAQ ++ PE ++G E+ AE+ Sbjct: 3 RVGLVQMTSGPEISRNLTYLKQEVAKLAQQGAQWIVTPENALLLGNREQYH-QQAESLDH 61 Query: 66 GPIQECMASLARQHGLWLVGGTLPLKADNPDKVLNTSLVYGPQGQRVARYDKIHLFNF-- 123 GP+Q +ASLA+++G+WL+ G++P++ + + V +SL++ QG+RVA YDK+H+F+ Sbjct: 62 GPVQHALASLAKEYGVWLLIGSMPIR--HAEGVTTSSLLWNAQGERVAVYDKLHMFDVDV 119 Query: 124 VRGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELY---RAMGECALIVMPAA 180 G + Y E+ T G +V PFG +GLS+CYD+RFP LY R G L+V PAA Sbjct: 120 ADGHQRYRESETFTPGQQVVVTSTPFGALGLSICYDVRFPHLYADLRRQGAQILLV-PAA 178 Query: 181 FTYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEG 240 FT TG+AHWE+LLRARAIE QC+V+A Q G H GR TWGHSM++ PWGE+++ L Sbjct: 179 FTAVTGQAHWEVLLRARAIETQCWVIAVGQTGHHPCGRETWGHSMVISPWGEVIANLGAE 238 Query: 241 EGLVIGDIDPHRLQYVRESLPALRHRKL 268 + + D L VR ++P +H + Sbjct: 239 VQSKVVEFDLATLDSVRRAMPITQHTRF 266 >alr2001 [R] COG0388 Predicted amidohydrolase Nos Nostoc sp. PCC 7120 Length = 271 Score = 214 bits (546), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 111/265 (41%), Positives = 173/265 (65%), Gaps = 9/265 (3%) Query: 8 AAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADGVGP 67 AAIQM S P++ +N A A L+ A ++GA+LV LPE + MG E+DKLA AEA + Sbjct: 7 AAIQMTSVPDLHKNLAQAEELIDLAVRRGAELVGLPENFSFMGE-EQDKLAQAEA--IAR 63 Query: 68 IQEC-MASLARQHGLWLVGGTLPLKADNPDKVLNTSLVYGPQGQRVARYDKIHLFNF-VR 125 E + ++A+++ + L+GG+ P+ + +V NT+++ P G+ +ARY+K+HLF+ V Sbjct: 64 ESEIFIKTMAQRYQVTLLGGSFPVPVSDTGRVYNTTILISPSGEELARYNKVHLFDVNVP 123 Query: 126 GEENYDEARTIEYGHEVQS--FEAPFGRVGLSVCYDLRFPELYRAMGE--CALIVMPAAF 181 Y E+ T+ G ++ F G +G+S+CYD+RFPELYR + + +I +PAAF Sbjct: 124 DGNTYRESSTVVAGQQLPPVHFSEYLGNIGVSICYDVRFPELYRHLSDKGTDIIFIPAAF 183 Query: 182 TYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEGE 241 T TG+ HW++LL+ARAIEN YV+A AQ G + R T GH++++DPWG I++ + Sbjct: 184 TAFTGKDHWQVLLQARAIENTAYVIAPAQTGNNYGRRLTHGHAVVIDPWGTILADAGDKP 243 Query: 242 GLVIGDIDPHRLQYVRESLPALRHR 266 G+ I +I+P RL+ VR +P+L+HR Sbjct: 244 GIAIAEINPSRLEQVRRQMPSLQHR 268 >sll0601 [R] COG0388 Predicted amidohydrolase Syn Synechocystis Length = 272 Score = 203 bits (516), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 111/265 (41%), Positives = 162/265 (61%), Gaps = 8/265 (3%) Query: 8 AAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADGVGP 67 AA+QM S P + EN A L+ A +QGA+LV LPE + +G +E +KL A A Sbjct: 7 AALQMTSRPNLTENLQEAEELIDLAVRQGAELVGLPENFAFLG-NETEKLEQATAIATA- 64 Query: 68 IQECMASLARQHGLWLVGGTLPLK-ADNPDKVLNTSLVYGPQGQRVARYDKIHLFNF-VR 125 ++ + ++A++ + ++ G P A K NT+ + P GQ +ARY K+HLF+ V Sbjct: 65 TEKFLQTMAQRFQVTILAGGFPFPVAGEAGKAYNTATLIAPNGQELARYHKVHLFDVNVP 124 Query: 126 GEENYDEARTIEYGHEVQSF--EAPFGRVGLSVCYDLRFPELYRAMGE--CALIVMPAAF 181 Y E+ T+ G + FG +GLS+CYD+RFPELYR + ++ +PAAF Sbjct: 125 DGNTYWESATVMAGQKYPPVYHSDSFGNLGLSICYDVRFPELYRYLSRQGADVLFVPAAF 184 Query: 182 TYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEGE 241 T TG+ HW++LL+ARAIEN CYV+A AQ G H R T GH+M++DPWG I++ E Sbjct: 185 TAYTGKDHWQVLLQARAIENTCYVIAPAQTGCHYERRHTHGHAMIIDPWGVILADAGEKP 244 Query: 242 GLVIGDIDPHRLQYVRESLPALRHR 266 GL I +I+P RL+ VR+ +P+L+HR Sbjct: 245 GLAIAEINPDRLKQVRQQMPSLQHR 269 >YPO3671 [R] COG0388 Predicted amidohydrolase Ype Yersinia pestis Length = 289 Score = 194 bits (494), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 103/270 (38%), Positives = 164/270 (60%), Gaps = 11/270 (4%) Query: 6 KVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADGV 65 VA +Q+ S +N A + + G +LV+ PE ++ + HAE Sbjct: 5 NVALLQLCSGENTRDNLAQIEQQIKQL-NAGIKLVMTPEN-ALLFANAASYRHHAEHHND 62 Query: 66 GPIQECMASLARQHGLWLVGGTLPLKA-DNPDKVLNTSLVYGPQGQRVARYDKIHLF--- 121 GP+Q+ + +AR++G+W+ G++P+ + ++PD + ++SL++ QG+ ARYDKIH+F Sbjct: 63 GPLQQEVREMARRYGVWIQVGSMPMVSRESPDLITSSSLLFDDQGELKARYDKIHMFDVD 122 Query: 122 -NFVRGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYRAMGE--CALIVMP 178 N + G +Y E+ T + G ++ + P GR+G+++CYDLRFP L++A+ +I +P Sbjct: 123 INDIHG--HYRESDTYQPGQQLTVVDTPVGRLGMTICYDLRFPGLFQALRAQGAEIISVP 180 Query: 179 AAFTYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLP 238 AAFT TG AHWE LLRARAIENQC +LA+AQ G H RRTWGH+M VD WG+I+ P Sbjct: 181 AAFTKMTGEAHWETLLRARAIENQCVILAAAQVGRHGATRRTWGHTMAVDAWGKIIGHNP 240 Query: 239 EGEGLVIGDIDPHRLQYVRESLPALRHRKL 268 + + I+ L+ +R +P ++H + Sbjct: 241 DAVAALKVRIETAGLKTIRNQMPVMQHNRF 270 >SMc02442 [R] COG0388 Predicted amidohydrolase Sme Sinorhizobium meliloti Length = 285 Score = 191 bits (484), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 107/269 (39%), Positives = 164/269 (60%), Gaps = 9/269 (3%) Query: 5 IKVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADG 64 K AA+Q+ S + A N + +LV AA +GA V PE + R +R L DG Sbjct: 3 FKAAAVQICSGVDPAGNAETMAKLVREAASRGATYVQTPEMTGAVQR-DRTGLRSVLKDG 61 Query: 65 VGPIQECMAS-LARQHGLWLVGGTLPL-KADNPDKVLNTSLVYGPQGQRVARYDKIHLFN 122 + AS LAR+ G++L G+ P+ +AD K+ N ++GP G ++ YDKIH+F+ Sbjct: 62 ENDVVVREASRLARELGIYLHVGSTPIARADG--KIANRGFLFGPDGAKICDYDKIHMFD 119 Query: 123 F-VRGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYR--AMGECALIVMPA 179 + E++ E+ G+ ++ + PFG++G S+CYD+RFPEL+R A+ ++ +PA Sbjct: 120 VDLENGESWRESAAYHPGNTARTADLPFGKLGFSICYDVRFPELFRQQAVAGAEIMSVPA 179 Query: 180 AFTYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVS-VLP 238 AFT TG AHWE+LLRARAIEN +V+A+AQ G H +GR T+GHSM+VDPWG +++ Sbjct: 180 AFTRQTGEAHWEILLRARAIENGLFVIAAAQAGTHEDGRETFGHSMIVDPWGRVLAEAGA 239 Query: 239 EGEGLVIGDIDPHRLQYVRESLPALRHRK 267 GE +++ +ID + R +P LR+ + Sbjct: 240 TGEEIIVAEIDVAAVHAARAKIPNLRNAR 268 >mll3450 [R] COG0388 Predicted amidohydrolase Mlo Mesorhizobium loti Length = 288 Score = 188 bits (477), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 107/268 (39%), Positives = 159/268 (59%), Gaps = 7/268 (2%) Query: 5 IKVAAIQMVSTPEVAENFASATRLVAAAAQQGAQLVLLPEYWPIMGRHERDKLAHAEADG 64 K AA+QM S N RLV AA QGA + PE + R ++ + A ++ Sbjct: 4 FKAAAVQMRSGESPERNAVDLERLVREAAGQGATYIQTPEMTGALIRDKQARAASFTSED 63 Query: 65 VGPIQECMASLARQHGLWL-VGGTLPLKADNPDKVLNTSLVYGPQGQRVARYDKIHLFNF 123 I LAR+ G++L +G T L+AD K+ N +L++GP G +A YDKIH+F+ Sbjct: 64 KDIIVATARGLARELGVFLHIGSTAILRADG--KLANRALLFGPDGATLATYDKIHMFDV 121 Query: 124 -VRGEENYDEARTIEYGHEVQSFEAPFGRVGLSVCYDLRFPELYR--AMGECALIVMPAA 180 + E++ E+ E G E E R+G +VCYDLRFP+L+R A+ ++ +PAA Sbjct: 122 DLDNGESWRESAAYEPGTEAVVTEVAGARLGFAVCYDLRFPQLFRTEALAGADVLTVPAA 181 Query: 181 FTYTTGRAHWELLLRARAIENQCYVLASAQGGEHVNGRRTWGHSMLVDPWGEIVSVLPEG 240 FT TG AHW +LLRARAIEN +V+A+AQGG H +GR T+GHS++VDPWG +++ Sbjct: 182 FTRQTGEAHWHVLLRARAIENGAFVVAAAQGGLHEDGRETYGHSLIVDPWGRVLAEAAHD 241 Query: 241 E-GLVIGDIDPHRLQYVRESLPALRHRK 267 E +V+ +IDP + R+ +P L++ + Sbjct: 242 EPAVVVAEIDPAQSLAARKKIPNLKNAR 269