BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0049.p (171 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2459 [MU] COG0597 Lipoprotein signal peptidase Rso Ralstonia ... 237 1e-62 NMB1832 [MU] COG0597 Lipoprotein signal peptidase Nme Neisseria ... 140 1e-33 NMA0623 [MU] COG0597 Lipoprotein signal peptidase NmA Neisseria ... 139 2e-33 YPO0476 [MU] COG0597 Lipoprotein signal peptidase Ype Yersinia p... 138 7e-33 VC0683 [MU] COG0597 Lipoprotein signal peptidase Vch Vibrio chol... 135 3e-32 ZlspA [MU] COG0597 Lipoprotein signal peptidase EcZ Escherichia ... 135 6e-32 ECs0030 [MU] COG0597 Lipoprotein signal peptidase Ecs Escherichi... 135 6e-32 lspA [MU] COG0597 Lipoprotein signal peptidase Eco Escherichia c... 134 1e-31 PA4559 [MU] COG0597 Lipoprotein signal peptidase Pae Pseudomonas... 131 6e-31 STM0047 [MU] COG0597 Lipoprotein signal peptidase Sty Salmonella... 131 6e-31 >RSc2459 [MU] COG0597 Lipoprotein signal peptidase Rso Ralstonia solanacearum Length = 173 Score = 237 bits (604), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 111/173 (64%), Positives = 141/173 (81%), Gaps = 3/173 (1%) Query: 1 MATKKRSSSSSASSST---QGLLPWLGIATIVLLLDQLSKITILKLFHYGDSLPVTGFFN 57 MAT+ S +A S + G+ PWLG+ I +LLDQL+KI ILK F YG+S P+TGFFN Sbjct: 1 MATRNNGKSKAAGSKSGGGHGVGPWLGLGVIWILLDQLTKIAILKTFAYGESRPITGFFN 60 Query: 58 LVLVYNKGAAFSFLAASGGWQRYLFTAIGIGAAVFIVHLLRKHPGQRMFCWALALILGGA 117 LVL YN+GAAFSFLAA+GGWQR+ FT +G+ AA+FIV LL++H GQ++FC+ALALILGGA Sbjct: 61 LVLAYNRGAAFSFLAAAGGWQRWFFTGLGVAAALFIVWLLKRHSGQKLFCFALALILGGA 120 Query: 118 IGNVIDRVVYGHVIDFLDVYVGNWHWPAFNIADSAICVGAVLFVVDELRRVSR 170 +GNVIDR+VYGHV+DFLD ++ +HWPAFN+AD IC+GAVL ++DELRRV R Sbjct: 121 LGNVIDRLVYGHVVDFLDFHLRGYHWPAFNVADCGICIGAVLLIIDELRRVRR 173 >NMB1832 [MU] COG0597 Lipoprotein signal peptidase Nme Neisseria meningitidis MC58 Length = 175 Score = 140 bits (354), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 81/167 (48%), Positives = 109/167 (65%), Gaps = 7/167 (4%) Query: 6 RSSSSSASSSTQGLLPWLGIATIVLLLDQLSKITILKLFHYGDSLPV-TGFFNLVLVYNK 64 ++ SSS SS T+ + L +A IVL DQ SK +L F Y + + V FF+L LVYN Sbjct: 9 KNMSSSVSSKTRYWV--LALAAIVL--DQWSKWAVLSSFQYRERVNVIPSFFDLTLVYNP 64 Query: 65 GAAFSFLAASGGWQRYLFTAIGIGAAVFIVHLLRKHPGQRMFCWALALILGGAIGNVIDR 124 GAAFSFLA GGWQ+Y F + + + ++V + + + A+I+GGA+GNVIDR Sbjct: 65 GAAFSFLADQGGWQKYFFLVLAVAVSAYLVRAILRDEFATLGKTGAAMIIGGALGNVIDR 124 Query: 125 VVYGHVIDFLDVYVGNWHWPAFNIADSAICVGAVLFVVDELRRVSRK 171 +++GHV+DFL Y NW +PAFNIADS ICVGAVL V+D + V RK Sbjct: 125 LIHGHVVDFLLFYWQNWFYPAFNIADSFICVGAVLAVLDNI--VHRK 169 >NMA0623 [MU] COG0597 Lipoprotein signal peptidase NmA Neisseria meningitidis Z2491 Length = 165 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 81/164 (49%), Positives = 107/164 (65%), Gaps = 7/164 (4%) Query: 9 SSSASSSTQGLLPWLGIATIVLLLDQLSKITILKLFHYGDSLPV-TGFFNLVLVYNKGAA 67 SSS SS T+ + L +A IVL DQ SK +L F Y + + V FF+L LVYN GAA Sbjct: 2 SSSVSSKTRYWV--LALAAIVL--DQWSKWAVLSSFQYRERVNVIPSFFDLTLVYNPGAA 57 Query: 68 FSFLAASGGWQRYLFTAIGIGAAVFIVHLLRKHPGQRMFCWALALILGGAIGNVIDRVVY 127 FSFLA GGWQ+Y F + + + ++V + + + A+I+GGA+GNVIDR+++ Sbjct: 58 FSFLADQGGWQKYFFLVLAVAVSAYLVRAILRDEFATLGKTGAAMIIGGALGNVIDRLIH 117 Query: 128 GHVIDFLDVYVGNWHWPAFNIADSAICVGAVLFVVDELRRVSRK 171 GHV+DFL Y NW +PAFNIADS ICVGAVL V+D + V RK Sbjct: 118 GHVVDFLLFYWQNWFYPAFNIADSFICVGAVLAVLDNI--VHRK 159 >YPO0476 [MU] COG0597 Lipoprotein signal peptidase Ype Yersinia pestis Length = 169 Score = 138 bits (347), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 71/145 (48%), Positives = 96/145 (66%), Gaps = 1/145 (0%) Query: 20 LPWLGIATIVLLLDQLSKITILKLFHYGDSLPVTGFFNLVLVYNKGAAFSFLAASGGWQR 79 L WL +A +V++LD SK ++ F +S+P+ FFNL N GAAFSFLA GWQR Sbjct: 10 LRWLWLAVVVVILDISSKQWVMAHFALYESVPLIPFFNLTYAQNFGAAFSFLADKSGWQR 69 Query: 80 YLFTAIGIG-AAVFIVHLLRKHPGQRMFCWALALILGGAIGNVIDRVVYGHVIDFLDVYV 138 + F I IG + V +V + R QR+ A ALI+GGA+GN+ DR+V+G V DFLD Y+ Sbjct: 70 WFFAGIAIGISVVLMVMMYRSTAKQRLINCAYALIIGGALGNLYDRLVHGAVNDFLDFYI 129 Query: 139 GNWHWPAFNIADSAICVGAVLFVVD 163 NWH+P FN+AD AIC+GA L + + Sbjct: 130 NNWHFPTFNLADVAICIGAALVIFE 154 >VC0683 [MU] COG0597 Lipoprotein signal peptidase Vch Vibrio cholerae Length = 171 Score = 135 bits (341), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 71/161 (44%), Positives = 103/161 (63%), Gaps = 3/161 (1%) Query: 9 SSSASSSTQGLLPWLGIATIVLLLDQLSKITILKLFHYG--DSLPVTGFFNLVLVYNKGA 66 S+S+ + Q L WL +A +V + D K+ ++ YG + + V FFNL+ V+N GA Sbjct: 2 SNSSLALKQSGLRWLWLALLVFIADITIKLIVMDNMGYGWANRIEVLPFFNLLYVHNYGA 61 Query: 67 AFSFLAASGGWQRYLFTAIGIGAAVFIVHLLRKHPG-QRMFCWALALILGGAIGNVIDRV 125 AFSFL+ GWQR+LFT I + + +R+ P + A ALI+GGA+GNV DR+ Sbjct: 62 AFSFLSDQEGWQRWLFTGIAFVVTGMLAYWMRRLPASDKWNNIAYALIIGGAVGNVFDRI 121 Query: 126 VYGHVIDFLDVYVGNWHWPAFNIADSAICVGAVLFVVDELR 166 V+G V+D+LD Y G +HWPAFN+ADS IC+GA + ++D R Sbjct: 122 VHGFVVDYLDFYWGTYHWPAFNLADSTICIGAAMIILDGFR 162 >ZlspA [MU] COG0597 Lipoprotein signal peptidase EcZ Escherichia coli O157:H7 EDL933 Length = 164 Score = 135 bits (339), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 71/145 (48%), Positives = 98/145 (67%), Gaps = 1/145 (0%) Query: 20 LPWLGIATIVLLLDQLSKITILKLFHYGDSLPVTGFFNLVLVYNKGAAFSFLAASGGWQR 79 L WL + +VL++D SK IL+ F GD++P+ NL N GAAFSFLA SGGWQR Sbjct: 10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQR 69 Query: 80 YLFTAIGIGAAV-FIVHLLRKHPGQRMFCWALALILGGAIGNVIDRVVYGHVIDFLDVYV 138 + F I IG +V +V + R Q++ A ALI+GGA+GN+ DR+ +G V+D +D YV Sbjct: 70 WFFAGIAIGISVTLVVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYV 129 Query: 139 GNWHWPAFNIADSAICVGAVLFVVD 163 G+WH+ FN+AD+AICVGA L V++ Sbjct: 130 GDWHFATFNLADTAICVGAALIVLE 154 >ECs0030 [MU] COG0597 Lipoprotein signal peptidase Ecs Escherichia coli O157:H7 Length = 164 Score = 135 bits (339), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 71/145 (48%), Positives = 98/145 (67%), Gaps = 1/145 (0%) Query: 20 LPWLGIATIVLLLDQLSKITILKLFHYGDSLPVTGFFNLVLVYNKGAAFSFLAASGGWQR 79 L WL + +VL++D SK IL+ F GD++P+ NL N GAAFSFLA SGGWQR Sbjct: 10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQR 69 Query: 80 YLFTAIGIGAAV-FIVHLLRKHPGQRMFCWALALILGGAIGNVIDRVVYGHVIDFLDVYV 138 + F I IG +V +V + R Q++ A ALI+GGA+GN+ DR+ +G V+D +D YV Sbjct: 70 WFFAGIAIGISVTLVVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYV 129 Query: 139 GNWHWPAFNIADSAICVGAVLFVVD 163 G+WH+ FN+AD+AICVGA L V++ Sbjct: 130 GDWHFATFNLADTAICVGAALIVLE 154 >lspA [MU] COG0597 Lipoprotein signal peptidase Eco Escherichia coli K12 Length = 164 Score = 134 bits (337), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 71/145 (48%), Positives = 98/145 (67%), Gaps = 1/145 (0%) Query: 20 LPWLGIATIVLLLDQLSKITILKLFHYGDSLPVTGFFNLVLVYNKGAAFSFLAASGGWQR 79 L WL + +VL++D SK IL+ F GD++P+ NL N GAAFSFLA SGGWQR Sbjct: 10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQR 69 Query: 80 YLFTAIGIGAAVFI-VHLLRKHPGQRMFCWALALILGGAIGNVIDRVVYGHVIDFLDVYV 138 + F I IG +V + V + R Q++ A ALI+GGA+GN+ DR+ +G V+D +D YV Sbjct: 70 WFFAGIAIGISVILAVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYV 129 Query: 139 GNWHWPAFNIADSAICVGAVLFVVD 163 G+WH+ FN+AD+AICVGA L V++ Sbjct: 130 GDWHFATFNLADTAICVGAALIVLE 154 >PA4559 [MU] COG0597 Lipoprotein signal peptidase Pae Pseudomonas aeruginosa Length = 169 Score = 131 bits (330), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 76/152 (50%), Positives = 99/152 (65%), Gaps = 3/152 (1%) Query: 18 GLLPWLGIATIVLLLDQLSKITI-LKLFHYGDSLPVTGFFNLVLVYNKGAAFSFLAASGG 76 G LPWL I +V +LDQ+SK +L Y + + F+ L YN GAAFSFLA S G Sbjct: 8 GRLPWLWITVLVFVLDQVSKAFFQAELSMYQQIVVIPDLFSWTLAYNTGAAFSFLADSSG 67 Query: 77 WQRYLFTAIGIG-AAVFIVHLLRKHPGQRMFCWALALILGGAIGNVIDRVVYGHVIDFLD 135 WQR+LF I I +A +V L R G+ ALAL+LGGA+GN+ DR+V GHV+DF+ Sbjct: 68 WQRWLFALIAIVVSASLVVWLKRLKKGETWLAIALALVLGGALGNLYDRMVLGHVVDFIL 127 Query: 136 VYVGN-WHWPAFNIADSAICVGAVLFVVDELR 166 V+ N W++PAFN+ADSAI VGAV+ +D R Sbjct: 128 VHWQNRWYFPAFNLADSAITVGAVMLALDMFR 159 >STM0047 [MU] COG0597 Lipoprotein signal peptidase Sty Salmonella typhimurium LT2 Length = 166 Score = 131 bits (330), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 71/145 (48%), Positives = 96/145 (66%), Gaps = 1/145 (0%) Query: 20 LPWLGIATIVLLLDQLSKITILKLFHYGDSLPVTGFFNLVLVYNKGAAFSFLAASGGWQR 79 L WL + +VL++D SK IL+ F GD++ + NL N GAAFSFLA SGGWQR Sbjct: 10 LRWLWLVVVVLIIDLGSKYLILQNFALGDTVGLFPSLNLHYARNYGAAFSFLADSGGWQR 69 Query: 80 YLFTAIGIGAAV-FIVHLLRKHPGQRMFCWALALILGGAIGNVIDRVVYGHVIDFLDVYV 138 + F I IG V +V + R Q++ A ALI+GGA+GN+ DR+ +G V+D +D YV Sbjct: 70 WFFAGIAIGICVILLVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYV 129 Query: 139 GNWHWPAFNIADSAICVGAVLFVVD 163 GNWH+ FN+ADSAIC+GA L V++ Sbjct: 130 GNWHFATFNLADSAICIGAALIVLE 154