BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0041.p (188 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 209 2e-54 PA3968 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 202 4e-52 HI0694 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 199 3e-51 PM1605 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 194 1e-49 NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 192 5e-49 ymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase a... 191 6e-49 YPO1640 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 191 1e-48 ECs1607 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthas... 190 2e-48 ZymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase ... 190 2e-48 VC1140 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase... 185 6e-47 >L189881 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Lla Lactococcus lactis Length = 185 Score = 209 bits (533), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 101/175 (57%), Positives = 130/175 (74%), Gaps = 2/175 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 +IL NKP+ V+++F+ R+TL DYI IPNVY AGRLD DSEGLLLLTDDGKL H + Sbjct: 9 IILFNKPYDVLTKFTDGEGRKTLKDYIKIPNVYAAGRLDKDSEGLLLLTDDGKLNHLLTD 68 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P+ K KTYL QVEG+ SPEA KL++ L L D T ++ +LI+EP W+W R PPIR+R Sbjct: 69 PKSKSYKTYLVQVEGEFSPEAAQKLQKGLLLKDGKTLPAKVKLIDEPDWLWERTPPIRER 128 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWR 177 + PTSW+ ++I EGKNRQ+RRMTAAVG PTLRL+R +IG +SL + GE++ Sbjct: 129 KAIPTSWVEISIKEGKNRQIRRMTAAVGFPTLRLIRWSIGQYSLGN--LKSGEYK 181 >PA3968 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Pae Pseudomonas aeruginosa Length = 189 Score = 202 bits (514), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 107/177 (60%), Positives = 131/177 (74%), Gaps = 3/177 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 L+L NKPF V++QF+ R TL D+I +P VYPAGRLD DSEGLLLLT+DG+LQ IA Sbjct: 11 LLLFNKPFDVLTQFNDEQGRSTLKDFIPVPGVYPAGRLDRDSEGLLLLTNDGRLQARIAD 70 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 PR KLPKTY QVEG P E L +LR+ + L D T ++ARL++EP +W R PP+R R Sbjct: 71 PRHKLPKTYWVQVEGTPDEEQLRRLREGVTLNDGPTLPAEARLLDEPT-LWERVPPVRFR 129 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 179 ++ PT W+ L I EG+NRQVRRMTAAVGLPTLRLVR+ IGP+SL + GEWREV Sbjct: 130 KSVPTHWLELVIREGRNRQVRRMTAAVGLPTLRLVRVRIGPWSLDGLGL--GEWREV 184 >HI0694 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Hin Haemophilus influenzae Length = 240 Score = 199 bits (505), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 94/164 (57%), Positives = 124/164 (75%), Gaps = 1/164 (0%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 ++L NKPF V++QF+ R TL D+I IPNVY AGRLD DSEGLL+LT++G+LQH +A Sbjct: 53 VVLFNKPFDVLTQFTDEQGRATLKDFISIPNVYAAGRLDRDSEGLLILTNNGELQHRLAD 112 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P+ K KTY QVEG P L +LR+ ++L D VT+ ++ RLI EP +W RNPPIR+R Sbjct: 113 PKFKTEKTYWVQVEGIPEETDLAQLRKGVELKDGVTKSAKVRLISEPN-LWERNPPIRER 171 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSL 166 +N PTSW+ + ISEG+NRQVRRMTA +G PTLRLVR+++G S+ Sbjct: 172 KNIPTSWLEIKISEGRNRQVRRMTAHIGFPTLRLVRVSMGLLSI 215 >PM1605 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Pmu Pasteurella multocida Length = 241 Score = 194 bits (492), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 95/182 (52%), Positives = 129/182 (70%), Gaps = 2/182 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 +IL NKP+ V++QFS R TL +I IP+VYPAGRLD DSEGL+LLT++G++QH +A Sbjct: 51 VILFNKPYDVLTQFSDEEGRATLKAFIPIPHVYPAGRLDRDSEGLVLLTNNGEIQHRLAV 110 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P+ KTY AQVEG P L +LRQ + L D T ++ RL+ EP W+W RNPPIR+R Sbjct: 111 PKFNTEKTYFAQVEGIPQETDLAQLRQGVVLNDGKTLPAKVRLVPEPNWLWQRNPPIRER 170 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREVDPL 182 + PTSW+ + I EG+NRQVRRMTA +G PTLRL+R + F+LA + G++R++ + Sbjct: 171 KQIPTSWLEIKIHEGRNRQVRRMTAHIGFPTLRLIRYQMALFNLAN--LEQGQYRQLSEV 228 Query: 183 EL 184 EL Sbjct: 229 EL 230 >NMB1496 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Nme Neisseria meningitidis MC58 Length = 186 Score = 192 bits (487), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 96/176 (54%), Positives = 121/176 (68%), Gaps = 2/176 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 LI NKP+ V+ QFS H + ++L D+I++P YPAGRLD DSEGLLLLTDDG+LQ I Sbjct: 4 LIAFNKPYGVICQFSPHEKHKSLKDFINLPGFYPAGRLDTDSEGLLLLTDDGRLQAQITD 63 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIE--EPGWMWPRNPPIR 120 P+ K PKTY AQ+EG P L+ LR+ +DLG FVT+ + R+++ E +W R PPIR Sbjct: 64 PKFKHPKTYWAQLEGVPDESRLESLRKGIDLGGFVTRPASIRILKHGEADSLWERIPPIR 123 Query: 121 QRQNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEW 176 R+ P WI +TISEGKNRQVRRMTA G P LRL+R+A G L + PGEW Sbjct: 124 VRKTVPDFWIEITISEGKNRQVRRMTAKAGYPCLRLIRVASGRLKLFDLDLKPGEW 179 >ymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Eco Escherichia coli K12 Length = 207 Score = 191 bits (486), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 93/177 (52%), Positives = 126/177 (71%), Gaps = 2/177 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 +IL NKP+ V+ QF+ R+TL ++I + VY AGRLD DSEGLL+LT++G LQ + Sbjct: 31 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 90 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P ++ K Y QVEG P+ +AL+ LR + L D T + A L++EP W+WPRNPPIR+R Sbjct: 91 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 150 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 179 ++ PTSW+ +T+ EG+NRQVRRMTA VG PTLRL+R A+G +SL + GEWREV Sbjct: 151 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDN--LANGEWREV 205 >YPO1640 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Ype Yersinia pestis Length = 208 Score = 191 bits (484), Expect = 1e-48, Method: Compositional matrix adjust. Identities = 92/177 (51%), Positives = 124/177 (70%), Gaps = 2/177 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 ++L NKPF V+ QF+ R TL +I +VY AGRLD DSEGLL+LT+DGKLQ + Sbjct: 31 VLLFNKPFDVLPQFTDESGRTTLQGFIPFKDVYAAGRLDRDSEGLLVLTNDGKLQARLTQ 90 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P +K K Y QVEG P +AL +L++ + L D +T + A L+ EP W+WPR+PPIR+R Sbjct: 91 PAQKTGKVYFVQVEGVPDNDALTQLKRGVTLKDGLTLPAGAELVAEPEWLWPRHPPIRER 150 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 179 + PTSW+ +T+ EG+NRQVRRMTA VG PTLRL+R ++G SL + PGEW+E+ Sbjct: 151 KTIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRFSMGNLSLGN--LQPGEWKEI 205 >ECs1607 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Ecs Escherichia coli O157:H7 Length = 217 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 92/177 (51%), Positives = 125/177 (70%), Gaps = 2/177 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 +IL NKP+ V+ QF+ R+TL ++I + VY AGRLD DSEGLL+LT++G LQ + Sbjct: 41 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 100 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P ++ K Y QVEG P+ +AL+ LR + L D T + A L++EP W+WPRNPPIR+R Sbjct: 101 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 160 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 179 ++ PTSW+ +T+ EG+NRQVRRMTA VG PTLRL+R A+G +SL + GEWRE Sbjct: 161 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDN--LANGEWREA 215 >ZymfC [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases EcZ Escherichia coli O157:H7 EDL933 Length = 207 Score = 190 bits (482), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 92/177 (51%), Positives = 125/177 (70%), Gaps = 2/177 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 +IL NKP+ V+ QF+ R+TL ++I + VY AGRLD DSEGLL+LT++G LQ + Sbjct: 31 VILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQ 90 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P ++ K Y QVEG P+ +AL+ LR + L D T + A L++EP W+WPRNPPIR+R Sbjct: 91 PGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER 150 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 179 ++ PTSW+ +T+ EG+NRQVRRMTA VG PTLRL+R A+G +SL + GEWRE Sbjct: 151 KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDN--LANGEWREA 205 >VC1140 [J] COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Vch Vibrio cholerae Length = 290 Score = 185 bits (469), Expect = 6e-47, Method: Compositional matrix adjust. Identities = 94/177 (53%), Positives = 124/177 (70%), Gaps = 3/177 (1%) Query: 3 LILLNKPFQVMSQFSAHPERQTLADYIDIPNVYPAGRLDADSEGLLLLTDDGKLQHAIAH 62 +IL NKP+ +SQF+ R+TLADYI I +VY AGRLD DSEGLL+LT+DG LQ + Sbjct: 115 VILFNKPYDTLSQFTDGDGRKTLADYIPIKDVYAAGRLDRDSEGLLILTNDGILQARLTQ 174 Query: 63 PRRKLPKTYLAQVEGQPSPEALDKLRQPLDLGDFVTQGSQARLIEEPGWMWPRNPPIRQR 122 P+ K PKTY QVEG P L+ LR + L D T ++ ++ EP +WPRNPP+R R Sbjct: 175 PQSKAPKTYWVQVEGSPQESDLEALRHGVTLKDGPTLPAKVDIMPEPT-LWPRNPPVRFR 233 Query: 123 QNQPTSWIALTISEGKNRQVRRMTAAVGLPTLRLVRIAIGPFSLATHPVMPGEWREV 179 PT+W+A+T+ EG+NRQVRRMTA +G PTLRL+R ++G ++L + PGEWREV Sbjct: 234 AAIPTTWLAITLMEGRNRQVRRMTAHIGFPTLRLIRYSMGDWNLGD--LQPGEWREV 288