BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0007.0028.p (259 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1527 [H] COG0294 Dihydropteroate synthase and related enzymes... 313 3e-85 PA4750 [H] COG0294 Dihydropteroate synthase and related enzymes ... 268 1e-71 VC0638 [H] COG0294 Dihydropteroate synthase and related enzymes ... 265 7e-71 HI1464 [H] COG0294 Dihydropteroate synthase and related enzymes ... 260 2e-69 HI1336 [H] COG0294 Dihydropteroate synthase and related enzymes ... 260 2e-69 YPO3501 [H] COG0294 Dihydropteroate synthase and related enzymes... 256 3e-68 XF0091 [H] COG0294 Dihydropteroate synthase and related enzymes ... 256 4e-68 PM0439 [H] COG0294 Dihydropteroate synthase and related enzymes ... 256 4e-68 folP [H] COG0294 Dihydropteroate synthase and related enzymes Ec... 256 5e-68 ZfolP [H] COG0294 Dihydropteroate synthase and related enzymes E... 256 5e-68 >RSc1527 [H] COG0294 Dihydropteroate synthase and related enzymes Rso Ralstonia solanacearum Length = 291 Score = 313 bits (802), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 161/259 (62%), Positives = 197/259 (76%), Gaps = 2/259 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGGRH D AL HAEQ+IA+G D+IDIGGES+RPG APL L+EEL+R Sbjct: 27 MGILNVTPDSFSDGGRHATRDAALRHAEQLIAEGADLIDIGGESSRPGAAPLGLQEELDR 86 Query: 61 VLPVIYALRDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLCV 120 V+P++ ALR+CG+PLS+DTYKP VMR L A D+INDI GFR GAIEAV AGLC+ Sbjct: 87 VMPIVEALRECGRPLSIDTYKPDVMRATLDAGADLINDIWGFRKPGAIEAVAQGHAGLCL 146 Query: 121 MHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHNL 180 MHMQ P+TMQ+AP Y D++ EV AFLQ Q ++ AG+A ERI +DPGFGFGKT +HNL Sbjct: 147 MHMQRDPETMQEAPSYTDLMAEVGAFLQAQAQVLLAAGVAAERIALDPGFGFGKTPDHNL 206 Query: 181 ALLKNTRRLIRQLGLPLLAGMSRKSMIGAVT-GKPLERRMAGSIGAALVAAQQGAMIIRV 239 +L R +GLPLL G+SRKS +GAV GKP R+ S+ AAL+AA++GA I+RV Sbjct: 207 IMLNRLEHFER-MGLPLLVGLSRKSTLGAVLGGKPPAERITASVAAALLAAERGAFIVRV 265 Query: 240 HDVAETVDALTLWQAGRED 258 HDV TV+A+ LW A R + Sbjct: 266 HDVRPTVEAIQLWWAMRHE 284 >PA4750 [H] COG0294 Dihydropteroate synthase and related enzymes Pae Pseudomonas aeruginosa Length = 283 Score = 268 bits (685), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 142/255 (55%), Positives = 181/255 (70%), Gaps = 2/255 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGGR+ RLD AL HAE+M+ +G +ID+GGESTRPG +S EELER Sbjct: 25 MGILNVTPDSFSDGGRYDRLDDALRHAERMVLEGATLIDVGGESTRPGARSVSPTEELER 84 Query: 61 VLPVIYAL-RDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLC 119 V PV+ + R+ +S+DT PAVMRE +IND+ + +GA++A DS +C Sbjct: 85 VAPVVERIARELDVVISVDTSTPAVMRETARLGAGLINDVRSLQRDGALDAAVDSGLAVC 144 Query: 120 VMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHN 179 +MHM+G+PQTMQ AP Y DVV EV AFLQ +VD AGI RER+ +DPGFGF KT+EHN Sbjct: 145 LMHMRGEPQTMQDAPAYQDVVAEVGAFLQERVDACVAAGIDRERLLLDPGFGFAKTLEHN 204 Query: 180 LALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRV 239 L L ++ + L LGLPLL G+SRKSMIG V G+ ++ R+ GS+ A +A +GA IIRV Sbjct: 205 LVLFRHLQAL-HGLGLPLLVGVSRKSMIGKVLGREVDERLYGSLALAALALAKGARIIRV 263 Query: 240 HDVAETVDALTLWQA 254 HDVA TVD + + A Sbjct: 264 HDVAATVDVMRMISA 278 >VC0638 [H] COG0294 Dihydropteroate synthase and related enzymes Vch Vibrio cholerae Length = 278 Score = 265 bits (677), Expect = 7e-71, Method: Compositional matrix adjust. Identities = 137/255 (53%), Positives = 177/255 (69%), Gaps = 3/255 (1%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILN TPDSFSDGGR+ LD+AL A+QMI GV IIDIGGESTRPG ++LEEEL+R Sbjct: 19 MGILNTTPDSFSDGGRYVDLDVALARAQQMIDLGVAIIDIGGESTRPGAPDVALEEELQR 78 Query: 61 VLPVIYALRDCGKP--LSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGL 118 V+P+I A+R +S+DT K VMR+AL A D+IND+ + GA+E ++ + Sbjct: 79 VIPLIKAIRKQNAEVWISIDTSKAEVMRQALAAGADLINDVRALQEPGALEVAAQAQVPV 138 Query: 119 CVMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEH 178 C+MHMQGQP+TMQ P Y++++ EV FL ++ AGI RE I +DPGFGFGK+V+H Sbjct: 139 CIMHMQGQPRTMQANPHYYNIIEEVCQFLAERIAQCEAAGIKRENIILDPGFGFGKSVQH 198 Query: 179 NLALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIR 238 N LL + + R GLP+LAGMSRKSMI K +AGS+ A +AAQ+GA IIR Sbjct: 199 NYHLLAHLEQFHR-FGLPVLAGMSRKSMIFKTLNKQPAECVAGSVACATLAAQKGAQIIR 257 Query: 239 VHDVAETVDALTLWQ 253 VHDV +T+DAL + Q Sbjct: 258 VHDVEQTIDALKMVQ 272 >HI1464 [H] COG0294 Dihydropteroate synthase and related enzymes Hin Haemophilus influenzae Length = 275 Score = 260 bits (665), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 134/257 (52%), Positives = 174/257 (67%), Gaps = 6/257 (2%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILN TPDSFSD G+ LD AL E+M+ +G IIDIGGESTRP +S +EEL R Sbjct: 18 MGILNFTPDSFSDSGQFFSLDKALFQVEKMLEEGATIIDIGGESTRPNADEVSEQEELHR 77 Query: 61 VLPVIYALR---DCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAG 117 V+PV+ A+R DC +S+D+ K VMREA +D+INDI + A+E Sbjct: 78 VVPVVEAVRNRFDCW--ISVDSSKAVVMREAANVGMDLINDIRALQEPNALETAVKLALP 135 Query: 118 LCVMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVE 177 +C+MHMQGQP+TMQ P Y +VV +V AFLQ++ + AGI +E + D GFGFGK+V+ Sbjct: 136 VCIMHMQGQPRTMQANPYYENVVQDVLAFLQKRTNECLSAGIKKENLIWDMGFGFGKSVQ 195 Query: 178 HNLALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMII 237 HN LL+N Q+G P+LAG+SRKSMIGAV KP+++R+ GS AL+A Q+GA I+ Sbjct: 196 HNYQLLQNLNEFC-QIGYPVLAGLSRKSMIGAVLDKPVDQRIIGSAAGALIAVQKGAKIL 254 Query: 238 RVHDVAETVDALTLWQA 254 RVHDVA T D L +WQA Sbjct: 255 RVHDVAATSDMLKVWQA 271 >HI1336 [H] COG0294 Dihydropteroate synthase and related enzymes Hin Haemophilus influenzae Length = 275 Score = 260 bits (665), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 134/257 (52%), Positives = 174/257 (67%), Gaps = 6/257 (2%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILN TPDSFSD G+ LD AL E+M+ +G IIDIGGESTRP +S +EEL R Sbjct: 18 MGILNFTPDSFSDSGQFFSLDKALFQVEKMLEEGATIIDIGGESTRPNADEVSEQEELHR 77 Query: 61 VLPVIYALR---DCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAG 117 V+PV+ A+R DC +S+D+ K VMREA +D+INDI + A+E Sbjct: 78 VVPVVEAVRNRFDCW--ISVDSSKAVVMREAANVGMDLINDIRALQEPNALETAVKLALP 135 Query: 118 LCVMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVE 177 +C+MHMQGQP+TMQ P Y +VV +V AFLQ++ + AGI +E + D GFGFGK+V+ Sbjct: 136 VCIMHMQGQPRTMQANPYYENVVQDVLAFLQKRTNECLSAGIKKENLIWDMGFGFGKSVQ 195 Query: 178 HNLALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMII 237 HN LL+N Q+G P+LAG+SRKSMIGAV KP+++R+ GS AL+A Q+GA I+ Sbjct: 196 HNYQLLQNLNEFC-QIGYPVLAGLSRKSMIGAVLDKPVDQRIIGSAAGALIAVQKGAKIL 254 Query: 238 RVHDVAETVDALTLWQA 254 RVHDVA T D L +WQA Sbjct: 255 RVHDVAATSDMLKVWQA 271 >YPO3501 [H] COG0294 Dihydropteroate synthase and related enzymes Ype Yersinia pestis Length = 277 Score = 256 bits (655), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 130/258 (50%), Positives = 176/258 (68%), Gaps = 2/258 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG H LD AL HA++M++ G +IDIGGESTRPG A +S +EEL+R Sbjct: 18 MGILNVTPDSFSDGGCHNNLDQALQHAQRMLSAGATLIDIGGESTRPGAAEVSEQEELDR 77 Query: 61 VLPVIYAL-RDCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLC 119 V+PV+ AL + LS+DT K AV+ E+ A +INDI + GA+EA + +C Sbjct: 78 VVPVVEALAQRFDVWLSVDTSKAAVITESAHAGAHLINDIRSLQEPGALEAAAKTGLPVC 137 Query: 120 VMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHN 179 +MHMQGQP+ MQ +P Y D++ ++ F Q ++ AGIA+ ++ +DPGFGFGK + HN Sbjct: 138 LMHMQGQPKNMQHSPYYDDLMTDINRFFQHHIERCVAAGIAKNKLLLDPGFGFGKNLAHN 197 Query: 180 LALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRV 239 LL + L LPLL GMSRKSM+G + P ++R+ GS+ A++AA QGA IIRV Sbjct: 198 YQLLAHLSEL-HHFELPLLVGMSRKSMVGQLLNVPPQQRVIGSVACAVIAAMQGAQIIRV 256 Query: 240 HDVAETVDALTLWQAGRE 257 HDV ETV+A+ + +A R Sbjct: 257 HDVKETVEAMCIVEATRS 274 >XF0091 [H] COG0294 Dihydropteroate synthase and related enzymes Xfa Xylella fastidiosa 9a5c Length = 298 Score = 256 bits (654), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 141/256 (55%), Positives = 176/256 (68%), Gaps = 6/256 (2%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG H +D A+ H ++IA+G DIIDIGGESTRPG AP+ LEEEL R Sbjct: 23 MGILNVTPDSFSDGGLHDSVDAAVAHGLRLIAEGADIIDIGGESTRPGAAPVPLEEELLR 82 Query: 61 VLPVIYALRDCGKP-LSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLC 119 V+PVI AL K +S+DT+KP VMR A+ A +INDI R GA+ A + + Sbjct: 83 VVPVIKALTAYDKAVISVDTFKPEVMRAAVAAGAGLINDIYALRTPGALGAAAELAVPVI 142 Query: 120 VMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHN 179 +MHM+G+P + Q PQY VV EV FL ++ AGI R R+ IDPGF F KT EHN Sbjct: 143 LMHMKGEPHS-TQTPQYDHVVDEVHRFLAERIFAAEIAGIERHRLLIDPGFSFSKTTEHN 201 Query: 180 LALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGK--PLERRMAGSIGAALVAAQQGAMII 237 +ALL R LG+PLLAG+SRKS +G +TG+ P+ER A S+ A L+A Q+GA+I+ Sbjct: 202 IALLAALERFT-NLGIPLLAGLSRKSSLGELTGRQLPIERVYA-SVAAHLIAVQRGALIV 259 Query: 238 RVHDVAETVDALTLWQ 253 RVHDVA VDAL +WQ Sbjct: 260 RVHDVAAMVDALKVWQ 275 >PM0439 [H] COG0294 Dihydropteroate synthase and related enzymes Pmu Pasteurella multocida Length = 275 Score = 256 bits (653), Expect = 4e-68, Method: Compositional matrix adjust. Identities = 136/260 (52%), Positives = 169/260 (65%), Gaps = 6/260 (2%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILN TPDSFSD G+ LD AL H E+M+ G IIDIGGESTRP ++LE+EL+R Sbjct: 18 MGILNFTPDSFSDSGQFFALDKALFHVEKMLNAGATIIDIGGESTRPMAEEVTLEQELDR 77 Query: 61 VLPVIYALR---DCGKPLSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAG 117 V+PV+ A+R DC +S+DT K VM+EA +D+INDI R A+ + Sbjct: 78 VIPVVEAVRQNFDCW--ISVDTSKAEVMKEAARVGMDLINDIRALREPNALLTAAQLDLP 135 Query: 118 LCVMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVE 177 +C+MHMQG+P+TMQQ P Y DVV EV AFLQ + AGI +E I D GFGFGKTV Sbjct: 136 VCIMHMQGEPRTMQQNPYYEDVVAEVFAFLQTRSAECISAGIRQENIIWDMGFGFGKTVV 195 Query: 178 HNLALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMII 237 HN LL+N G P+LAG+SRKSMIG V K +E R+ GS+ AL+A GA I+ Sbjct: 196 HNYKLLQNLAHFCAA-GFPVLAGLSRKSMIGNVLDKAVEDRVVGSVAGALIAMVHGAAIV 254 Query: 238 RVHDVAETVDALTLWQAGRE 257 RVHDV T DAL +WQA + Sbjct: 255 RVHDVEHTADALKIWQATKN 274 >folP [H] COG0294 Dihydropteroate synthase and related enzymes Eco Escherichia coli K12 Length = 297 Score = 256 bits (653), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 131/255 (51%), Positives = 171/255 (67%), Gaps = 2/255 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG H L A+ HA MI G IID+GGESTRPG A +S+EEEL+R Sbjct: 33 MGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQR 92 Query: 61 VLPVIYALRDCGKP-LSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLC 119 V+PV+ A+ + +S+DT KP V+RE+ +INDI GA+EA ++ +C Sbjct: 93 VIPVVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVC 152 Query: 120 VMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHN 179 +MHMQG P+TMQ+AP+Y DV EV + Q+ QAGIA+E++ +DPGFGFGK + HN Sbjct: 153 LMHMQGNPKTMQEAPKYDDVFAEVNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHN 212 Query: 180 LALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRV 239 +LL LPLL GMSRKSMIG + R++GS+ A++AA QGA IIRV Sbjct: 213 YSLLARLAEF-HHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRV 271 Query: 240 HDVAETVDALTLWQA 254 HDV ETV+A+ + +A Sbjct: 272 HDVKETVEAMRVVEA 286 >ZfolP [H] COG0294 Dihydropteroate synthase and related enzymes EcZ Escherichia coli O157:H7 EDL933 Length = 297 Score = 256 bits (653), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 131/255 (51%), Positives = 171/255 (67%), Gaps = 2/255 (0%) Query: 1 MGILNVTPDSFSDGGRHQRLDMALTHAEQMIADGVDIIDIGGESTRPGIAPLSLEEELER 60 MGILNVTPDSFSDGG H L A+ HA MI G IID+GGESTRPG A +S+EEEL+R Sbjct: 33 MGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQR 92 Query: 61 VLPVIYALRDCGKP-LSLDTYKPAVMREALLAEVDMINDINGFRAEGAIEAVRDSEAGLC 119 V+PV+ A+ + +S+DT KP V+RE+ +INDI GA+EA ++ +C Sbjct: 93 VIPVVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVC 152 Query: 120 VMHMQGQPQTMQQAPQYHDVVGEVEAFLQRQVDLMRQAGIARERICIDPGFGFGKTVEHN 179 +MHMQG P+TMQ+AP+Y DV EV + Q+ QAGIA+E++ +DPGFGFGK + HN Sbjct: 153 LMHMQGNPKTMQEAPKYDDVFAEVNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHN 212 Query: 180 LALLKNTRRLIRQLGLPLLAGMSRKSMIGAVTGKPLERRMAGSIGAALVAAQQGAMIIRV 239 +LL LPLL GMSRKSMIG + R++GS+ A++AA QGA IIRV Sbjct: 213 YSLLARLAEF-HHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRV 271 Query: 240 HDVAETVDALTLWQA 254 HDV ETV+A+ + +A Sbjct: 272 HDVKETVEAMRVVEA 286