BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0053.p (227 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1232 [G] COG0120 Ribose 5-phosphate isomerase Rso Ralstonia s... 283 2e-76 rpiA [G] COG0120 Ribose 5-phosphate isomerase Eco Escherichia co... 275 9e-74 ZrpiA [G] COG0120 Ribose 5-phosphate isomerase EcZ Escherichia c... 275 9e-74 ECs3785 [G] COG0120 Ribose 5-phosphate isomerase Ecs Escherichia... 275 9e-74 STM3063 [G] COG0120 Ribose 5-phosphate isomerase Sty Salmonella ... 274 1e-73 YPO0915 [G] COG0120 Ribose 5-phosphate isomerase Ype Yersinia pe... 266 2e-71 PA0330 [G] COG0120 Ribose 5-phosphate isomerase Pae Pseudomonas ... 261 8e-70 VC2480 [G] COG0120 Ribose 5-phosphate isomerase Vch Vibrio cholerae 252 6e-67 HI0464 [G] COG0120 Ribose 5-phosphate isomerase Hin Haemophilus ... 243 2e-64 NMA1711 [G] COG0120 Ribose 5-phosphate isomerase NmA Neisseria m... 226 2e-59 >RSc1232 [G] COG0120 Ribose 5-phosphate isomerase Rso Ralstonia solanacearum Length = 228 Score = 283 bits (725), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 147/228 (64%), Positives = 181/228 (79%), Gaps = 5/228 (2%) Query: 1 MTQDELKQAVAKAAIEYVV----DGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEAT 56 MTQDELK VA+AA +YV+ +G ++GVGTGSTAN FID + K R GAV+SSEA+ Sbjct: 1 MTQDELKALVAQAAADYVLANVPEGAVLGVGTGSTANLFIDAMAPHKARFAGAVSSSEAS 60 Query: 57 AERLRSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCI 116 RL+ HG V DLNEV+T+PVY+DGADEI+ GAMIKGGG ALTREKIVASVA +FVCI Sbjct: 61 TRRLQGHGFAVLDLNEVDTIPVYVDGADEIDDTGAMIKGGGGALTREKIVASVAGRFVCI 120 Query: 117 ADGSKLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRV-KDGKPVVTDNGCYIIDV 175 ADGSKLV+VLG FPLPVEV+PM+ A VAR+LAALGG+PRLR+ K+G+ TDNG I+DV Sbjct: 121 ADGSKLVDVLGAFPLPVEVVPMARAAVARQLAALGGQPRLRMTKEGQIYQTDNGNVILDV 180 Query: 176 LGLSITDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKLEF 223 GL I +P +E +IN+I GVVT GLFA++GA+V LLGT GV++ +F Sbjct: 181 SGLRIGEPKTLEAQINDIPGVVTVGLFAKRGADVLLLGTEAGVQRRDF 228 >rpiA [G] COG0120 Ribose 5-phosphate isomerase Eco Escherichia coli K12 Length = 219 Score = 275 bits (702), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 141/221 (63%), Positives = 175/221 (79%), Gaps = 4/221 (1%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 MTQDELK+AV AA++YV G I+GVGTGSTA FID LG +K +I+GAV+SS+A+ E+L Sbjct: 1 MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 +S GI VFDLNEV+++ +Y+DGADEING MIKGGGAALTREKI+ASVA+KF+CIAD S Sbjct: 61 KSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADAS 120 Query: 121 KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI 180 K V++LGKFPLPVEVIPM+ + VAR+L LGG P R + VVTDNG I+DV G+ I Sbjct: 121 KQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYR----QGVVTDNGNVILDVHGMEI 176 Query: 181 TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKL 221 DP +E+ IN I GVVT GLFA +GA+V L+GT DGVK + Sbjct: 177 LDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTI 217 >ZrpiA [G] COG0120 Ribose 5-phosphate isomerase EcZ Escherichia coli O157:H7 EDL933 Length = 219 Score = 275 bits (702), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 141/221 (63%), Positives = 175/221 (79%), Gaps = 4/221 (1%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 MTQDELK+AV AA++YV G I+GVGTGSTA FID LG +K +I+GAV+SS+A+ E+L Sbjct: 1 MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 +S GI VFDLNEV+++ +Y+DGADEING MIKGGGAALTREKI+ASVA+KF+CIAD S Sbjct: 61 KSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADAS 120 Query: 121 KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI 180 K V++LGKFPLPVEVIPM+ + VAR+L LGG P R + VVTDNG I+DV G+ I Sbjct: 121 KQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYR----QGVVTDNGNVILDVHGMEI 176 Query: 181 TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKL 221 DP +E+ IN I GVVT GLFA +GA+V L+GT DGVK + Sbjct: 177 LDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTI 217 >ECs3785 [G] COG0120 Ribose 5-phosphate isomerase Ecs Escherichia coli O157:H7 Length = 219 Score = 275 bits (702), Expect = 9e-74, Method: Compositional matrix adjust. Identities = 141/221 (63%), Positives = 175/221 (79%), Gaps = 4/221 (1%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 MTQDELK+AV AA++YV G I+GVGTGSTA FID LG +K +I+GAV+SS+A+ E+L Sbjct: 1 MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 +S GI VFDLNEV+++ +Y+DGADEING MIKGGGAALTREKI+ASVA+KF+CIAD S Sbjct: 61 KSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADAS 120 Query: 121 KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI 180 K V++LGKFPLPVEVIPM+ + VAR+L LGG P R + VVTDNG I+DV G+ I Sbjct: 121 KQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYR----QGVVTDNGNVILDVHGMEI 176 Query: 181 TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKL 221 DP +E+ IN I GVVT GLFA +GA+V L+GT DGVK + Sbjct: 177 LDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTI 217 >STM3063 [G] COG0120 Ribose 5-phosphate isomerase Sty Salmonella typhimurium LT2 Length = 219 Score = 274 bits (700), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 140/221 (63%), Positives = 174/221 (78%), Gaps = 4/221 (1%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 MTQDELK+AV AA++YV G I+GVGTGSTA FID LG +K +I+GAV+SS+A+ E+L Sbjct: 1 MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 + GI VFDLNEV+++ +Y+DGADEING MIKGGGAALTREKI+ASVA+KF+CIAD S Sbjct: 61 KGLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADAS 120 Query: 121 KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI 180 K V++LGKFPLPVEVIPM+ + VAR+L LGG P R + VVTDNG I+DV G+ I Sbjct: 121 KQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYR----QNVVTDNGNVILDVYGMEI 176 Query: 181 TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKL 221 DP +E+ IN I GVVT GLFA +GA+V L+GT DGVK + Sbjct: 177 LDPIALENAINAIPGVVTVGLFANRGADVALIGTPDGVKTI 217 >YPO0915 [G] COG0120 Ribose 5-phosphate isomerase Ype Yersinia pestis Length = 218 Score = 266 bits (681), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 138/219 (63%), Positives = 173/219 (78%), Gaps = 4/219 (1%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 MTQDELK+AV AA++YV G I+GVGTGSTA FID LG IKH+I+GAV+SS+A+ +L Sbjct: 1 MTQDELKKAVGWAALDYVKPGTIVGVGTGSTAAHFIDALGSIKHQIEGAVSSSDASTAKL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 +S+GI VFD N+V+ + +Y+DGADEING MIKGGGAALTREKI+A++A+KF+CIAD S Sbjct: 61 KSYGIPVFDCNDVDVLDIYVDGADEINGQMQMIKGGGAALTREKIIAAIARKFICIADES 120 Query: 121 KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI 180 K V VLGKFPLPVEVIPM+ + VAR+L LGG P R + V+TDNG I+DV LSI Sbjct: 121 KQVGVLGKFPLPVEVIPMARSYVARELIKLGGLPEYR----QNVLTDNGNVILDVHNLSI 176 Query: 181 TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVK 219 D +E++IN I GVVT GLFA +GA+V L+GTA+GVK Sbjct: 177 LDAIALENQINGIAGVVTVGLFANRGADVALIGTANGVK 215 >PA0330 [G] COG0120 Ribose 5-phosphate isomerase Pae Pseudomonas aeruginosa Length = 223 Score = 261 bits (668), Expect = 8e-70, Method: Compositional matrix adjust. Identities = 137/226 (60%), Positives = 172/226 (76%), Gaps = 8/226 (3%) Query: 1 MTQDELKQAVAKAAIEYVV----DGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEAT 56 M QD+LKQAVA+AA+++++ I+GVGTGSTANFFID L + K GAVASSEAT Sbjct: 1 MNQDQLKQAVAQAAVDHILPHLDSKSIVGVGTGSTANFFIDALARHKAEFDGAVASSEAT 60 Query: 57 AERLRSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCI 116 A+RL+ HGI V++LN V + Y+DGADE N +IKGGGAALTREKIVA+VA+ F+CI Sbjct: 61 AKRLKEHGIPVYELNTVSELEFYVDGADESNERLELIKGGGAALTREKIVAAVAKTFICI 120 Query: 117 ADGSKLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVL 176 AD SKLV +LG+FPLPVEVIPM+ + VAR+L LGG+P R + V+TDNG I+DV Sbjct: 121 ADASKLVPILGQFPLPVEVIPMARSHVARQLVKLGGDPVYR----EGVLTDNGNIILDVH 176 Query: 177 GLSITDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKLE 222 L I P ++E+KIN IVGVVTNGLFA + A++ LLGTADGVK L+ Sbjct: 177 NLRIDSPVELEEKINAIVGVVTNGLFAARPADLLLLGTADGVKTLK 222 >VC2480 [G] COG0120 Ribose 5-phosphate isomerase Vch Vibrio cholerae Length = 218 Score = 252 bits (643), Expect = 6e-67, Method: Compositional matrix adjust. Identities = 131/219 (59%), Positives = 162/219 (73%), Gaps = 4/219 (1%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 MTQDE+K+A AA++YV G I+GVGTGST N FID LG IK IKGAV+SS A+ +L Sbjct: 1 MTQDEMKKAAGWAALKYVEKGSIVGVGTGSTVNHFIDALGTIKDEIKGAVSSSIASTAKL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 + GI V+D N+V + +Y+DGADEIN MIKGGGAALTREKIVA++A+KFVCI DG+ Sbjct: 61 EALGIRVYDCNDVSELDIYVDGADEINPERDMIKGGGAALTREKIVAAIAKKFVCIVDGT 120 Query: 121 KLVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSI 180 K V+VLG FPLPVEVIPM+ + VAR+L LGG+P R + V+TDNG I+DV + I Sbjct: 121 KAVDVLGNFPLPVEVIPMARSYVARELVKLGGDPVYR----EGVITDNGNVILDVYNMKI 176 Query: 181 TDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVK 219 T P D+E KIN I GVVT GLFA +GA+V + GT G K Sbjct: 177 THPKDLESKINGIAGVVTVGLFAHRGADVVITGTPQGAK 215 >HI0464 [G] COG0120 Ribose 5-phosphate isomerase Hin Haemophilus influenzae Length = 219 Score = 243 bits (621), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 125/223 (56%), Positives = 167/223 (74%), Gaps = 5/223 (2%) Query: 1 MTQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERL 60 M Q E+K+ A+AA++YV I+GVG+GST N FI+ LG IK +I+GAVA+S+ + E L Sbjct: 1 MNQLEMKKLAAQAALQYVKADTIVGVGSGSTVNCFIEALGTIKDKIQGAVAASKESEELL 60 Query: 61 RSHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGS 120 R GI VF+ N+V ++ +Y+DGADEIN MIKGGGAALTREKIVA++A+KF+CI D S Sbjct: 61 RKQGIEVFNANDVSSLDIYVDGADEINPQKMMIKGGGAALTREKIVAALAKKFICIVDSS 120 Query: 121 KLVEVLGK-FPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLS 179 K V+VLG FPLPVEVIPM+ + V RKLAALGG P R + VVTDNG I+DV S Sbjct: 121 KQVDVLGSTFPLPVEVIPMARSQVGRKLAALGGSPEYR----EGVVTDNGNVILDVHNFS 176 Query: 180 ITDPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVKKLE 222 I +P ++E ++NN+ GVVTNG+FA +GA+V ++GT +G K ++ Sbjct: 177 ILNPVEIEKELNNVAGVVTNGIFALRGADVVIVGTPEGAKVID 219 >NMA1711 [G] COG0120 Ribose 5-phosphate isomerase NmA Neisseria meningitidis Z2491 Length = 223 Score = 226 bits (577), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 119/218 (54%), Positives = 154/218 (70%), Gaps = 4/218 (1%) Query: 2 TQDELKQAVAKAAIEYVVDGEIIGVGTGSTANFFIDELGKIKHRIKGAVASSEATAERLR 61 TQDELK+ A+ A+E+V + E IG+GTGST NFFI+ LGK +IKGAV++S+ ++E L Sbjct: 3 TQDELKRIAAEKAVEFVPENEYIGIGTGSTINFFIEALGKSGKKIKGAVSTSKKSSELLA 62 Query: 62 SHGITVFDLNEVETMPVYIDGADEINGGGAMIKGGGAALTREKIVASVAQKFVCIADGSK 121 + I V LNEV + VYIDGADE+N MIKGGG A EKIVAS ++KFVCIAD SK Sbjct: 63 QYDIPVVSLNEVSGLAVYIDGADEVNHALQMIKGGGGAHLNEKIVASASEKFVCIADESK 122 Query: 122 LVEVLGKFPLPVEVIPMSHAVVARKLAALGGEPRLRVKDGKPVVTDNGCYIIDVLGLSIT 181 V LGKFPLPVEV+ + ++V+RKL A+GG+P LR+ T G I+DV GL+I Sbjct: 123 YVSRLGKFPLPVEVVESARSLVSRKLLAMGGQPELRIG----YTTFYGNQIVDVHGLNID 178 Query: 182 DPADVEDKINNIVGVVTNGLFARQGANVCLLGTADGVK 219 P +ED+IN I GV+ NG+FAR A+V +LGT +G K Sbjct: 179 QPLTMEDEINKITGVLENGIFARDAADVLILGTEEGAK 216