BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0006.0048.p (1355 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1251 [L] COG1643 HrpA-like helicases Rso Ralstonia solanacearum 1786 0.0 STM1641 [L] COG1643 HrpA-like helicases Sty Salmonella typhimuri... 1148 0.0 hrpA [L] COG1643 HrpA-like helicases Eco Escherichia coli K12 1134 0.0 ZhrpA [L] COG1643 HrpA-like helicases EcZ Escherichia coli O157:... 1132 0.0 ECs2015 [L] COG1643 HrpA-like helicases Ecs Escherichia coli O15... 1132 0.0 YPO2322 [L] COG1643 HrpA-like helicases Ype Yersinia pestis 1123 0.0 VC1382 [L] COG1643 HrpA-like helicases Vch Vibrio cholerae 1100 0.0 PM0769 [L] COG1643 HrpA-like helicases Pmu Pasteurella multocida 1096 0.0 HI1070 [L] COG1643 HrpA-like helicases Hin Haemophilus influenzae 1065 0.0 PA3297 [L] COG1643 HrpA-like helicases Pae Pseudomonas aeruginosa 1043 0.0 >RSc1251 [L] COG1643 HrpA-like helicases Rso Ralstonia solanacearum Length = 1331 Score = 1786 bits (4627), Expect = 0.0, Method: Compositional matrix adjust. Identities = 926/1363 (67%), Positives = 1067/1363 (78%), Gaps = 63/1363 (4%) Query: 8 TPAPAAQPQKNPQQERAGGQRDARGPRRTDSAAEAAPAPAPLRNPLPPVTFPEELPVSGR 67 +P A++P + Q AGG+R R ++ A A A N +PP++FPE LPVS R Sbjct: 17 SPNDASRPARQAGQADAGGRRPRRQKPTPEALAAALEARRARANAVPPISFPEALPVSAR 76 Query: 68 RHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKG----LIGHTQPRRIAASST 123 R EIA A+ AHQV+IVSGETGSGKTTQLPKICL +GRG LIGHTQPRRIAA+ST Sbjct: 77 RDEIARAVAAHQVVIVSGETGSGKTTQLPKICLSIGRGIGAGGTGLIGHTQPRRIAATST 136 Query: 124 AKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLLRQYDTIIIDE 183 AKRIAQE+ SP GE VGY+VRFNDTLS GA +KLMTDGILLAETQ DPLLR YDTIIIDE Sbjct: 137 AKRIAQEIGSPLGEHVGYQVRFNDTLSAGASVKLMTDGILLAETQNDPLLRGYDTIIIDE 196 Query: 184 AHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGREVKGEIVPAPVIEVS 243 AHERSLNIDFLLGYLKQLLP+RPDLK+IITSATIDA RFA HF G PAPVIEVS Sbjct: 197 AHERSLNIDFLLGYLKQLLPRRPDLKVIITSATIDAQRFAEHFA----GPKGPAPVIEVS 252 Query: 244 GRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMDAVVDAVDELA 303 GRLYPVE+RYRP+ + +KD+E RDL D +VDAVDELA Sbjct: 253 GRLYPVEVRYRPV-----------------------QRDEKDKE-RDLYDGIVDAVDELA 288 Query: 304 RIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVFKTSNARRIVL 363 R GAGDVL+FLPGEREIR+AAEALRKHHP H EILPLFARLS QEQERVF+ SNARRIVL Sbjct: 289 REGAGDVLIFLPGEREIREAAEALRKHHPAHTEILPLFARLSVQEQERVFRPSNARRIVL 348 Query: 364 ATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQRAGRCGRVAAG 423 ATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPV+Q+AANQRAGRCGRVA G Sbjct: 349 ATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVSQAAANQRAGRCGRVADG 408 Query: 424 VCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEPPLGRAIADGY 483 VCIRLY+E DF+ RP+FTDPEILRSSLA+VILRMK+L LTDVE FPFIEPPLGRAIADGY Sbjct: 409 VCIRLYEEADFIARPRFTDPEILRSSLAAVILRMKALRLTDVEQFPFIEPPLGRAIADGY 468 Query: 484 QLLQELGAVEEHGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLTELLIIAAAVSVQ 543 QLLQELGAV++ N LTPLGKQ+ARLPLDPRV RMILAGRD+ CL E+LIIA+A+SVQ Sbjct: 469 QLLQELGAVDDE---NALTPLGKQVARLPLDPRVARMILAGRDHQCLREMLIIASALSVQ 525 Query: 544 DPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNRQLQEHCRENFLS 603 DPRDRP + Q AD AH++FADEKSEF ++K+WKWFE+A+AHKKSN+QLQ+ CR +FLS Sbjct: 526 DPRDRPQELQQQADQAHRQFADEKSEFLGWVKLWKWFEEAVAHKKSNKQLQDQCRAHFLS 585 Query: 604 QLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGNVGFKSED----DAQ 659 LRLREWRDVHSQL T V EQGW+LNE+ TY+QLHLALLTGLLGN+G + E+ + Sbjct: 586 HLRLREWRDVHSQLHTTVAEQGWKLNESEPTYEQLHLALLTGLLGNIGVRIEEADGKGRE 645 Query: 660 YLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKLGGHLLKKS 719 YLGARGIKF +WPG+ + +K G+W++A EL++T+RL+ R +A I+PEW+EK+G HLLK S Sbjct: 646 YLGARGIKFFLWPGSAIARKAGKWMVAGELIETSRLFGRTLARIEPEWVEKVGAHLLKVS 705 Query: 720 WGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRDALVGGDFETRA 779 W +P WEK+A QV A ER TLYGL VY QRR+++G + P EARE+FIR ALV G+FETR Sbjct: 706 WSDPHWEKKAGQVMAFERGTLYGLPVYQQRRVHFGPMQPREARELFIRRALVDGEFETRL 765 Query: 780 PFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDFEKWHKEATAA 839 PFFAHNQ+LVREIENLEHKSRR DVLVDDELI FYD IP DI N V FE W+ EA A Sbjct: 766 PFFAHNQRLVREIENLEHKSRRQDVLVDDELIHAFYDSQIPADIHNTVAFEGWYAEAAKA 825 Query: 840 DPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVTLTVPLYAL 899 KLLYLNRDDLMRHEAAG+TT+LFPKT+ +AGI M L+YHFEPG+ RDGVTLTVPLYAL Sbjct: 826 SQKLLYLNRDDLMRHEAAGITTDLFPKTLPIAGIDMGLTYHFEPGSPRDGVTLTVPLYAL 885 Query: 900 NQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEERKTFGRGNL 959 NQV A R EWLVPGMLKEK HLLLKSLPQKLRRHCVPLPDYAA F R+ G G+L Sbjct: 886 NQVPAQRAEWLVPGMLKEKAHLLLKSLPQKLRRHCVPLPDYAAGFVSRVR----LGDGDL 941 Query: 960 IDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAALQAEFGGQ 1019 +D +IAD+REQ +K +DFK ETL AHH MNFK++DEHGRQL+MGRNLA L+AE GG+ Sbjct: 942 LDRLIADVREQTGTPLKRADFKLETLPAHHFMNFKVIDEHGRQLDMGRNLAQLRAELGGR 1001 Query: 1020 ARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPASVGEYSNLTSWSFG 1079 A+Q FQ +A + A D A P GKGG APA A YS LT+W+FG Sbjct: 1002 AQQTFQSIAAKDAAVAGAPGDGAGARP----GKGGKPDAPANPA-----LYSGLTTWNFG 1052 Query: 1080 ELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLRRLFALQMK 1139 ELPELLE+ +GS QTL G+PALVD HCD+EVFDDPAEAAR H GLRRLFALQ++ Sbjct: 1053 ELPELLEVRKGS----QTLFGYPALVDGGDHCDVEVFDDPAEAARIHRLGLRRLFALQLR 1108 Query: 1140 EQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQDPLPRNADEFNRRRDE 1199 E LKYLEKNIPGL QM +QFM LG+Q+ELR QIL+A L+RA LQDPLP + F R+DE Sbjct: 1109 EPLKYLEKNIPGLSQMAIQFMTLGAQDELRNQILDAALDRACLQDPLPADDAGFGARKDE 1168 Query: 1200 GKARLGLLVNEIARLCGQILAEYHALPKKLQGIKAHAQAAADMQAQLSQLVGKRFVAETD 1259 G+ RL LL EIARL G ILAEY LP+KLQ K A AD+ AQL L+ KRF+ T Sbjct: 1169 GRTRLTLLAQEIARLAGAILAEYAQLPRKLQIAKPFGAAYADIDAQLKALMHKRFIEATP 1228 Query: 1260 YGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRALKD-------RAGRA 1312 Y L+H+PRYLK I +R+DKL+ADP RDT+ + E + YQRA K RA Sbjct: 1229 YAQLAHFPRYLKGIAMRIDKLKADPTRDTQRMQEMAPLFQQYQRAEKQLRVQGQGRAAAG 1288 Query: 1313 DPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESMQR 1355 DP+M EFRWMLEELR++L+AQEL+TP+P+SVKRLQKVWESMQR Sbjct: 1289 DPRMEEFRWMLEELRIALFAQELRTPVPMSVKRLQKVWESMQR 1331 >STM1641 [L] COG1643 HrpA-like helicases Sty Salmonella typhimurium LT2 Length = 1300 Score = 1148 bits (2970), Expect = 0.0, Method: Compositional matrix adjust. Identities = 608/1338 (45%), Positives = 853/1338 (63%), Gaps = 92/1338 (6%) Query: 17 KNPQQERAGGQRDARGPRRTDSAAEAAPAPAPLRNPL-PPVTFPEELPVSGRRHEIAAAL 75 KNP ++A Q A+ E A A LR P +T+P+ LPVS ++ +I A+ Sbjct: 38 KNPDAQQAIFQTMAK-------EIEQAAAQVALREAARPSITYPQNLPVSQKKQDILEAI 90 Query: 76 RAHQVIIVSGETGSGKTTQLPKICLELGRGEKGLIGHTQPRRIAASSTAKRIAQELNSPP 135 R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHTQPRR+AA + A RIA+EL + P Sbjct: 91 RDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELQTEP 150 Query: 136 GELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLLRQYDTIIIDEAHERSLNIDFLL 195 G +GYKVRF+D +S +KLMTDGILLAE Q D LL QYDT+IIDEAHERSLNIDFLL Sbjct: 151 GGCIGYKVRFSDHVSSNTMVKLMTDGILLAEIQQDRLLMQYDTLIIDEAHERSLNIDFLL 210 Query: 196 GYLKQLLPKRPDLKIIITSATIDADRFARHFGREVKGEIVPAPVIEVSGRLYPVEIRYRP 255 GYLK+LLP+RPDLK+IITSATID +RF+RHF AP+IEVSGR YPVE+RYRP Sbjct: 211 GYLKELLPRRPDLKVIITSATIDPERFSRHFNN--------APIIEVSGRTYPVEVRYRP 262 Query: 256 IDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMDAVVDAVDELARIGAGDVLVFLP 315 I V +A D +RD + A+ DAVDEL R GD+L+F+ Sbjct: 263 I-----------VEEA-------------DDTERDQLQAIFDAVDELGRESPGDILIFMS 298 Query: 316 GEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVFKTSNARRIVLATNVAETSLTVP 375 GEREIRD A+AL K + H E+LPL+ARLS EQ RVF++ + RRIVLATNVAETSLTVP Sbjct: 299 GEREIRDTADALNKLNLRHTEVLPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVP 358 Query: 376 GIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQRAGRCGRVAAGVCIRLYDEQDFL 435 GI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR GRCGRV+ G+CIRLY E DFL Sbjct: 359 GIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRCGRVSEGICIRLYSEDDFL 418 Query: 436 QRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEPPLGRAIADGYQLLQELGAV--E 493 RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E P R I DG +LL+ELGA+ + Sbjct: 419 SRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITAD 478 Query: 494 EHGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLTELLIIAAAVSVQDPRDRPMDAQ 553 E +LTPLG+QL++LP+DPR+ RM+L + + C+ E +II +A+S+QDPR+RP+D Q Sbjct: 479 EQQTAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPVDKQ 538 Query: 554 NAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNRQLQEHCRENFLSQLRLREWRDV 613 A+D H++F D++S+F +++ +W + + SN Q + CR ++L+ LR+REW+D+ Sbjct: 539 QASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN-QFRRLCRTDYLNYLRVREWQDI 597 Query: 614 HSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGNVGFKSEDDAQYLGARGIKFNIWPG 673 ++QL +VKE G +N PA Y ++H+ALLTGLL ++G K D +Y GAR +F+I+PG Sbjct: 598 YTQLRQVVKELGIPVNSEPAEYREIHVALLTGLLSHIGMKDADKQEYTGARNARFSIFPG 657 Query: 674 AHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKLGGHLLKKSWGEPRWEKRAAQVT 733 + L KKP +W M AELV+T+RL+ R A I+PEW+E + HL+K+S+ EP WE+ V Sbjct: 658 SGLFKKPPKWTMVAELVETSRLWGRIAARIEPEWVEPVAQHLIKRSYSEPHWERAQGAVM 717 Query: 734 ASERATLYGLVVYSQRRINYGKINPAEAREIFIRDALVGGDFETRAPFFAHNQKLVREIE 793 A+E+ T+YGL + + R++NY +I+PA RE+FIR ALV GD++TR FF N KL E+E Sbjct: 718 ATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVE 777 Query: 794 NLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDFEKWHKEATAADPKLLYLNRDDLMR 853 LEHKSRR D+LVDD+ + FYD+ I HD+ + F+ W K+ + P LL + L++ Sbjct: 778 ELEHKSRRRDILVDDDTLFEFYDQRISHDVISARHFDSWWKKISRETPDLLNFEKSMLIK 837 Query: 854 HEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVTLTVPLYALNQVSADRCEWLVPG 913 A ++ +P + + + LSY FEPGA DGVT+ +PL LNQV EW +PG Sbjct: 838 EGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPLPLLNQVDESGFEWQIPG 897 Query: 914 MLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEERKTFGRGNLIDAIIADIREQITL 973 + +E V L+KSLP+ +RR+ VP P+YA F R+ T L+DA+ ++R + Sbjct: 898 LRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRV----TPLELPLLDALERELRRMTGV 953 Query: 974 LVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAALQAEFGGQARQQFQKLAEQVAI 1033 V D+ + + H + F++V++ ++L+ GR+LA L+ G+ ++ +A+ Sbjct: 954 TVDREDWHWDQVPEHLKITFRVVNDKNKKLQEGRSLAELKNALKGKVQETLSAVADDGI- 1012 Query: 1034 APREDEDNAAPSPAAATGKGGTSAAPAAAAPASVGEYSNLTSWSFGELPELLEITRGSGK 1093 E S L WSFGELPE E RG+ K Sbjct: 1013 -----------------------------------EQSGLHIWSFGELPESYEQKRGNYK 1037 Query: 1094 QAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLRRLFALQMKEQLKYLEKNIPGLQ 1153 + +PALVD + +++FD+P E + + GLRRL L + +KYL + +P Sbjct: 1038 ----VKAWPALVDERDSVAIKLFDNPLEQQQAMWCGLRRLLLLNIPSPIKYLHEKLPNKA 1093 Query: 1154 QMGMQFMALGSQEELREQILNAGLERAFLQDPLPRNADE-FNRRRDEGKARLGLLVNEIA 1212 ++G+ F G EL + + G+++ + P ++ F ++ +A L V +IA Sbjct: 1094 KLGLYFNPYGKVLELIDDCIACGVDKLIDANGGPVWSEAGFTALHEKVRAELNDTVVDIA 1153 Query: 1213 RLCGQILAEYHALPKKLQG--IKAHAQAAADMQAQLSQLVGKRFVAETDYGNLSHYPRYL 1270 + +IL + K+L+G + A +D++AQ+S LV + FV + L RYL Sbjct: 1154 KQVERILTTVFNINKRLKGRVDMSMALGLSDIKAQMSGLVYRGFVTGNGFKRLGDTLRYL 1213 Query: 1271 KAINVRLDKLRADPARDTRLLAEWNSVALPYQRALKDR--AGRADPKMTEFRWMLEELRV 1328 +AI RL+KL DP RD + + SV +Q+ + A R D + E RWM+EELRV Sbjct: 1214 QAIEKRLEKLAVDPHRDRAQMLKVESVQQAWQQWINKLPPARREDDDVKEIRWMIEELRV 1273 Query: 1329 SLYAQELKTPMPVSVKRL 1346 S +AQ+L TP P+S KR+ Sbjct: 1274 SYFAQQLGTPYPISDKRI 1291 >hrpA [L] COG1643 HrpA-like helicases Eco Escherichia coli K12 Length = 1281 Score = 1134 bits (2933), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1307 (45%), Positives = 841/1307 (64%), Gaps = 84/1307 (6%) Query: 54 PPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGLIGHT 113 P +T+P+ LPVS ++ +I A+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 50 PEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 109 Query: 114 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 173 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 110 QPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLL 169 Query: 174 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGREVKGE 233 QYDTIIIDEAHERSLNIDFLLGYLK+LLP+RPDLKIIITSATID +RF+RHF Sbjct: 170 MQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNN----- 224 Query: 234 IVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 293 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 225 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 257 Query: 294 AVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 353 A+ DAVDEL++ GD+L+F+ GEREIRD A+AL K + H EILPL+ARLS EQ RVF Sbjct: 258 AIFDAVDELSQESHGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVF 317 Query: 354 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 413 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 318 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 377 Query: 414 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 473 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 378 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 437 Query: 474 PLGRAIADGYQLLQELGAV--EEHGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 531 P R I DG +LL+ELGA+ +E +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 438 PDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 497 Query: 532 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 591 E +II +A+S+QDPR+RPMD Q A+D H++F D++S+F +++ +W + + SN Sbjct: 498 EAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 556 Query: 592 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGNVG 651 + CR ++L+ LR+REW+D+++QL +VKE G +N PA Y ++H+ALLTGLL ++G Sbjct: 557 AFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIG 616 Query: 652 FKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 711 K D +Y GAR +F+I+PG+ L KKP +WVM AELV+T+RL+ R A I PEW+E + Sbjct: 617 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPV 676 Query: 712 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRDALV 771 HL+K+++ EP WE+ V A+E+ T+YGL + + R++NY +I+PA RE+FIR ALV Sbjct: 677 AQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 736 Query: 772 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDFEK 831 GD++TR FF N KL E+E LEHKSRR D+LVDDE + FYD+ I HD+ + F+ Sbjct: 737 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRISHDVISARHFDS 796 Query: 832 WHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 891 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 797 WWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 856 Query: 892 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 951 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R++ Sbjct: 857 VHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVKPL 916 Query: 952 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1011 + L+D++ ++R + V D+ + + H + F++VD+ ++L+ GR+L Sbjct: 917 EL----PLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQD 972 Query: 1012 LQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPASVGEYS 1071 L+ G+ ++ +A+ E S Sbjct: 973 LKDALKGKVQETLSAVADDGI------------------------------------EQS 996 Query: 1072 NLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLR 1131 L WSFG+LPE E RG+ K + +PALVD + +++FD+P E + + GLR Sbjct: 997 GLHIWSFGQLPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLR 1052 Query: 1132 RLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQDPLPRNAD 1191 RL L + +KYL + +P ++G+ F G EL + ++ G+++ + P + Sbjct: 1053 RLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDKLIDANGGPVWTE 1112 Query: 1192 E-FNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQG--IKAHAQAAADMQAQLSQ 1248 E F ++ +A L V +IA+ QIL + K+L+G A +D++AQ+ Sbjct: 1113 EGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGG 1172 Query: 1249 LVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRALKDR 1308 LV + FV + L RYL+AI RL+KL DP RD + + +V +Q+ + Sbjct: 1173 LVYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKL 1232 Query: 1309 --AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1353 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ + E + Sbjct: 1233 PPARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQI 1279 >ZhrpA [L] COG1643 HrpA-like helicases EcZ Escherichia coli O157:H7 EDL933 Length = 1281 Score = 1132 bits (2929), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1307 (45%), Positives = 839/1307 (64%), Gaps = 84/1307 (6%) Query: 54 PPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGLIGHT 113 P +T+P+ LPVS ++ +I A+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 50 PEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 109 Query: 114 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 173 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 110 QPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLL 169 Query: 174 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGREVKGE 233 QYDTIIIDEAHERSLNIDFLLGYLK+LLP+RPDLKIIITSATID +RF+RHF Sbjct: 170 MQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNN----- 224 Query: 234 IVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 293 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 225 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 257 Query: 294 AVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 353 A+ DAVDEL++ GD+L+F+ GEREIRD A+AL K + H EILPL+ARLS EQ RVF Sbjct: 258 AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVF 317 Query: 354 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 413 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 318 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 377 Query: 414 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 473 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 378 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 437 Query: 474 PLGRAIADGYQLLQELGAV--EEHGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 531 P R I DG +LL+ELGA+ +E +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 438 PDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 497 Query: 532 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 591 E +II +A+S+QDPR+RPMD Q A+D H++F D++S+F +++ +W + + SN Sbjct: 498 EAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 556 Query: 592 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGNVG 651 + CR ++L+ LR+REW+D+++QL +VKE G +N PA Y ++H+ALLTGLL ++G Sbjct: 557 AFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIG 616 Query: 652 FKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 711 K D +Y GAR +F+I+PG+ L KKP +WVM AELV+T+RL+ R A I PEW+E + Sbjct: 617 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPV 676 Query: 712 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRDALV 771 HL+K+++ EP WE+ V A+E+ T+YGL + + R++NY +I+PA RE+FIR ALV Sbjct: 677 AQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 736 Query: 772 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDFEK 831 GD++TR FF N KL E+E LEHKSRR D+LVDDE + FYD+ I HD+ + F+ Sbjct: 737 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRIGHDVISARHFDS 796 Query: 832 WHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 891 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 797 WWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 856 Query: 892 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 951 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R+ Sbjct: 857 VHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPL 916 Query: 952 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1011 + L+D++ ++R + V D+ + + H + F++VD+ ++L+ GR+L Sbjct: 917 EL----PLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQD 972 Query: 1012 LQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPASVGEYS 1071 L+ G+ ++ +A+ E S Sbjct: 973 LKDALKGKVQETLSAVADDGI------------------------------------EQS 996 Query: 1072 NLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLR 1131 L WSFG+LPE E RG+ K + +PALVD + +++FD+P E + + GLR Sbjct: 997 GLHIWSFGQLPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLR 1052 Query: 1132 RLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQDPLPRNAD 1191 RL L + +KYL + +P ++G+ F G EL + ++ G+++ + P + Sbjct: 1053 RLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTE 1112 Query: 1192 E-FNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQG--IKAHAQAAADMQAQLSQ 1248 E F ++ +A L V +IA+ QIL + K+L+G A +D++AQ+ Sbjct: 1113 EGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGG 1172 Query: 1249 LVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRALKDR 1308 LV + FV + L RYL+AI RL+KL DP RD + + +V +Q+ Sbjct: 1173 LVYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWFNKL 1232 Query: 1309 --AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1353 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ + E + Sbjct: 1233 PPARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQI 1279 >ECs2015 [L] COG1643 HrpA-like helicases Ecs Escherichia coli O157:H7 Length = 1281 Score = 1132 bits (2929), Expect = 0.0, Method: Compositional matrix adjust. Identities = 598/1307 (45%), Positives = 839/1307 (64%), Gaps = 84/1307 (6%) Query: 54 PPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGLIGHT 113 P +T+P+ LPVS ++ +I A+R HQV+IV+GETGSGKTTQLPKIC+ELGRG KGLIGHT Sbjct: 50 PEITYPDNLPVSQKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHT 109 Query: 114 QPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLL 173 QPRR+AA + A RIA+EL + PG +GYKVRF+D +S +KLMTDGILLAE Q D LL Sbjct: 110 QPRRLAARTVANRIAEELKTEPGGCIGYKVRFSDHVSDNTMVKLMTDGILLAEIQQDRLL 169 Query: 174 RQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGREVKGE 233 QYDTIIIDEAHERSLNIDFLLGYLK+LLP+RPDLKIIITSATID +RF+RHF Sbjct: 170 MQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRHFNN----- 224 Query: 234 IVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 293 AP+IEVSGR YPVE+RYRPI V +A D +RD + Sbjct: 225 ---APIIEVSGRTYPVEVRYRPI-----------VEEA-------------DDTERDQLQ 257 Query: 294 AVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 353 A+ DAVDEL++ GD+L+F+ GEREIRD A+AL K + H EILPL+ARLS EQ RVF Sbjct: 258 AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNRVF 317 Query: 354 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 413 ++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 318 QSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 377 Query: 414 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 473 GRCGRV+ G+CIRLY E DFL RP+FTDPEILR++LASVIL+M +L L D+ +FPF+E Sbjct: 378 KGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEA 437 Query: 474 PLGRAIADGYQLLQELGAV--EEHGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNACLT 531 P R I DG +LL+ELGA+ +E +LTPLG+QL++LP+DPR+ RM+L + + C+ Sbjct: 438 PDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVR 497 Query: 532 ELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKSNR 591 E +II +A+S+QDPR+RPMD Q A+D H++F D++S+F +++ +W + + SN Sbjct: 498 EAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLGEQQKALSSN- 556 Query: 592 QLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGNVG 651 + CR ++L+ LR+REW+D+++QL +VKE G +N PA Y ++H+ALLTGLL ++G Sbjct: 557 AFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIG 616 Query: 652 FKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLEKL 711 K D +Y GAR +F+I+PG+ L KKP +WVM AELV+T+RL+ R A I PEW+E + Sbjct: 617 MKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPV 676 Query: 712 GGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRDALV 771 HL+K+++ EP WE+ V A+E+ T+YGL + + R++NY +I+PA RE+FIR ALV Sbjct: 677 AQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQIDPALCRELFIRHALV 736 Query: 772 GGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDFEK 831 GD++TR FF N KL E+E LEHKSRR D+LVDDE + FYD+ I HD+ + F+ Sbjct: 737 EGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYDQRIGHDVISARHFDS 796 Query: 832 WHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDGVT 891 W K+ + P LL + L++ A ++ +P + + + LSY FEPGA DGVT Sbjct: 797 WWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVT 856 Query: 892 LTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERMEER 951 + +PL LNQV EW +PG+ +E V L+KSLP+ +RR+ VP P+YA F R+ Sbjct: 857 VHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPL 916 Query: 952 KTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNLAA 1011 + L+D++ ++R + V D+ + + H + F++VD+ ++L+ GR+L Sbjct: 917 EL----PLLDSLERELRRMTGVTVDREDWHWDQVPDHLKITFRVVDDKNKKLKEGRSLQD 972 Query: 1012 LQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPASVGEYS 1071 L+ G+ ++ +A+ E S Sbjct: 973 LKDALKGKVQETLSAVADDGI------------------------------------EQS 996 Query: 1072 NLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLR 1131 L WSFG+LPE E RG+ K + +PALVD + +++FD+P E + + GLR Sbjct: 997 GLHIWSFGQLPESYEQKRGNYK----VKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLR 1052 Query: 1132 RLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQDPLPRNAD 1191 RL L + +KYL + +P ++G+ F G EL + ++ G+++ + P + Sbjct: 1053 RLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTE 1112 Query: 1192 E-FNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQG--IKAHAQAAADMQAQLSQ 1248 E F ++ +A L V +IA+ QIL + K+L+G A +D++AQ+ Sbjct: 1113 EGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGG 1172 Query: 1249 LVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRALKDR 1308 LV + FV + L RYL+AI RL+KL DP RD + + +V +Q+ Sbjct: 1173 LVYRGFVTGNGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWFNKL 1232 Query: 1309 --AGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1353 A R D + E RWM+EELRVS +AQ+L TP P+S KR+ + E + Sbjct: 1233 PPARREDEDVKEIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQI 1279 >YPO2322 [L] COG1643 HrpA-like helicases Ype Yersinia pestis Length = 1280 Score = 1123 bits (2905), Expect = 0.0, Method: Compositional matrix adjust. Identities = 591/1311 (45%), Positives = 837/1311 (63%), Gaps = 85/1311 (6%) Query: 50 RNPLPPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGL 109 R P +++P+ LPVS ++ +I A+R HQVIIV+GETGSGKTTQLPKICLELGRG KG+ Sbjct: 46 RAACPAISYPDNLPVSQKKQDIYNAIRDHQVIIVAGETGSGKTTQLPKICLELGRGVKGV 105 Query: 110 IGHTQPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQT 169 IGHTQPRR+AA + A RIA EL++ G VGYKVRFND + + +KLMTDGILLAE Q Sbjct: 106 IGHTQPRRLAARTVANRIADELDTSLGGCVGYKVRFNDQVGENTLVKLMTDGILLAEIQQ 165 Query: 170 DPLLRQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRE 229 D LL QYDT+IIDEAHERSLNIDF+LGYL++LLPKRPDLK+IITSATID RF++HF Sbjct: 166 DRLLMQYDTLIIDEAHERSLNIDFILGYLRELLPKRPDLKVIITSATIDPQRFSQHFNN- 224 Query: 230 VKGEIVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQR 289 AP+IEVSGR YPVE+RYRPI + + Sbjct: 225 -------APIIEVSGRTYPVEVRYRPIVDDADDVDRDQ---------------------- 255 Query: 290 DLMDAVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQ 349 + A+ DAVDEL R AGD+L+F+ GEREIRD A+AL K + PH E+LPL+ARLS EQ Sbjct: 256 --LQAIFDAVDELGRESAGDILIFMSGEREIRDTADALIKQNLPHTEVLPLYARLSNSEQ 313 Query: 350 ERVFKTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSA 409 RVF++ + RRIVLATNVAETSLTVPGI+YV+D G AR+ RYS+R KV++L IEP++Q++ Sbjct: 314 NRVFQSHHGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSFRTKVQRLPIEPISQAS 373 Query: 410 ANQRAGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFP 469 ANQR GRCGRV+ G+CIRLY EQDFL RP+FTDPEILR++LASVIL+M SL L D+ +FP Sbjct: 374 ANQRKGRCGRVSDGICIRLYSEQDFLSRPEFTDPEILRTNLASVILQMTSLGLGDIAAFP 433 Query: 470 FIEPPLGRAIADGYQLLQELGAVEE-HGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNA 528 F+E P R I DG +LL+ELGA++ G +LTPLG+QLA+LP+DPR+ RM+L + + Sbjct: 434 FVEAPDKRNIQDGVRLLEELGAIQTASNGHQQLTPLGRQLAQLPVDPRLARMVLQAQKSG 493 Query: 529 CLTELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKK 588 C+ EL+II +A+S+QDPR+RP+D Q A+D H++FAD+ S+F +++ +W + ++ Sbjct: 494 CVRELMIITSALSIQDPRERPVDKQQASDEKHRRFADKDSDFLAFVNLWDYLKEQ-QKAL 552 Query: 589 SNRQLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLG 648 S+ Q ++ CR ++L+ LR+REW+D+++QL +VKE G +N A Y +H A+LTGLL Sbjct: 553 SSAQFRKLCRSDYLNYLRVREWQDIYTQLRQVVKELGIPVNSVAADYRSVHTAILTGLLS 612 Query: 649 NVGFKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWL 708 ++G K + ++ GAR +F I+PG+ L KKP +WVM AELV+T+RL+ R A I+PEW+ Sbjct: 613 HIGQKDVEKQEFTGARNARFAIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIEPEWI 672 Query: 709 EKLGGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRD 768 E L HL+K + +P WEK V ASE+ TL+GL + ++R+INYG I+P RE+FIR Sbjct: 673 EPLAQHLVKHHYSDPHWEKAQGAVMASEKVTLFGLPIVTERKINYGPIDPLLCRELFIRH 732 Query: 769 ALVGGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVD 828 LV GD++TR FF N KL+ E+E LEHKSRR D+LVDDE + FYD+ I D+ + + Sbjct: 733 GLVEGDWQTRHAFFRMNLKLLAEVEELEHKSRRRDILVDDETLFNFYDQRIGRDVISALH 792 Query: 829 FEKWHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARD 888 F+ W K+A+ P+LL + L++ A V +P + + L Y FEPG D Sbjct: 793 FDSWWKQASQTKPELLNFEKTMLIKEGANKVNPLDYPNFWYQGELKLRLFYQFEPGTDAD 852 Query: 889 GVTLTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERM 948 GVT+ +PL LNQ+ +W +PG+ +E V L+KSLP+ +RR+ VP P+YA F R+ Sbjct: 853 GVTVHIPLPILNQIHEQGFDWQIPGIRRELVIALIKSLPKPVRRNFVPAPNYADAFLARV 912 Query: 949 EERKTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRN 1008 +T L++A+ ++R + V ++ + + H + F+++D+ R L G++ Sbjct: 913 TPLET----GLLEALERELRRMTGVTVSRDSWQLDQVPDHLKITFRVLDDKNRILREGKD 968 Query: 1009 LAALQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPASVG 1068 LAAL+ + + ++ +A+ Sbjct: 969 LAALKLQLQEKVQETLSAVADDGI------------------------------------ 992 Query: 1069 EYSNLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYA 1128 E +NL WSFG+LP E RG G + + +PALVD K + +FD ++ + + Sbjct: 993 EQNNLHIWSFGDLPICYEQRRG-GYEVK---AYPALVDEKDSVAIRLFDTESQQQQAMWQ 1048 Query: 1129 GLRRLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQD--PL 1186 G RRL L + +KYL + +P ++G+ F G+ +L + + G+++ Q P+ Sbjct: 1049 GTRRLLLLNIPSPIKYLHEKLPNKSKLGLYFNTYGNVMDLIDDCIACGVDKLVAQHGGPV 1108 Query: 1187 PRNADEFNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQG--IKAHAQAAADMQA 1244 + AD F R +++ +A L V +IA+ QIL ++ K+L+G + A +D++A Sbjct: 1109 WQEAD-FARLQEKVRAELNDTVVDIAKQVEQILTLVFSINKRLKGRIDISLVLALSDIKA 1167 Query: 1245 QLSQLVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRA 1304 QL+ L+ + FV + L RYLKAI RL+KL DP RD + V +Q+ Sbjct: 1168 QLAGLIYRGFVTSNGWKRLPDTLRYLKAIERRLEKLAVDPHRDRAQMLRIEHVQQVWQQW 1227 Query: 1305 LKDRAGR--ADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKVWESM 1353 L + D ++ E RWM+EELRVSL+AQ+L TP PVS KR+ + E + Sbjct: 1228 LNKLPPKRQQDEEVKEVRWMIEELRVSLFAQQLGTPYPVSDKRILQTIEQL 1278 >VC1382 [L] COG1643 HrpA-like helicases Vch Vibrio cholerae Length = 1309 Score = 1100 bits (2846), Expect = 0.0, Method: Compositional matrix adjust. Identities = 607/1377 (44%), Positives = 846/1377 (61%), Gaps = 109/1377 (7%) Query: 3 VTKAPTPAPAAQPQKNP--QQERAGGQ---RD-ARGPRRTDSA----------------- 39 + PTP AAQP+ N ++A G+ +D R +R D A Sbjct: 2 TSSQPTPDSAAQPKANSAASLKKALGECLIKDRFRFSKRIDGASKIKNESARNAVFDEIA 61 Query: 40 ---AEAAPAPAPLRNPLPPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLP 96 A++ + +P + +P LPVS +R +IA A+ HQV+IV+GETGSGKTTQLP Sbjct: 62 LDIAQSMMVVEQRKQQMPKIEYPALLPVSQKRDDIAQAIAHHQVVIVAGETGSGKTTQLP 121 Query: 97 KICLELGRGEKGLIGHTQPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIK 156 KIC ELGRG+ GLIGHTQPRR+AA S A RIA+E+ + G VGYKVRF D +S IK Sbjct: 122 KICAELGRGKYGLIGHTQPRRLAARSVANRIAEEMETELGGFVGYKVRFTDQISDQTQIK 181 Query: 157 LMTDGILLAETQTDPLLRQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSAT 216 LMTDGILLAE Q D L QYDTIIIDEAHERSLNIDF+LGYLKQLLP+RPDLK+IITSAT Sbjct: 182 LMTDGILLAEIQNDRFLNQYDTIIIDEAHERSLNIDFILGYLKQLLPRRPDLKVIITSAT 241 Query: 217 IDADRFARHFGREVKGEIVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAE 276 ID +RF++HF AP+IEVSGR YPVE+RYRP+ D S Sbjct: 242 IDPERFSKHFSN--------APIIEVSGRTYPVEVRYRPLAGDDDS-------------- 279 Query: 277 GRASQAQKDREQRDLMDAVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVE 336 + DR+Q ++ + AVDEL G GD+L+F+ GEREIRD A+AL K + E Sbjct: 280 ------ESDRDQ---LEGIFQAVDELCDEGLGDILIFMNGEREIRDTADALSKRNLRDTE 330 Query: 337 ILPLFARLSAQEQERVFKTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNK 396 I+PL+ARLSA EQ ++F+ RRIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR K Sbjct: 331 IVPLYARLSAGEQNKIFQPHAGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTK 390 Query: 397 VEQLQIEPVAQSAANQRAGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILR 456 V++L IEP++Q++ANQR GRCGR G+CIRLY E+DFL RP+FTDPEILR++LASVIL+ Sbjct: 391 VQRLPIEPISQASANQRKGRCGRTEEGICIRLYSEEDFLSRPEFTDPEILRTNLASVILQ 450 Query: 457 MKSLHLTDVESFPFIEPPLGRAIADGYQLLQELGAVEEH--GGVNRLTPLGKQLARLPLD 514 M +L L D+E+FPF+E P R I DG +LL+ELGA+ + RLT GKQLARLP+D Sbjct: 451 MTALGLGDIEAFPFVEAPDKRNIQDGVRLLEELGAINDQIKDPKKRLTESGKQLARLPID 510 Query: 515 PRVGRMILAGRDNACLTELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYL 574 PR+ RM+L CL E++IIA+A+S+QDPR+RP D Q +AD+ H++F E S+F + + Sbjct: 511 PRLARMVLEASKLGCLKEVMIIASALSIQDPRERPSDKQQSADDKHRRFNHEDSDFLTLV 570 Query: 575 KIWKWFEDAIAHKKSNRQLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPAT 634 +W + SN Q + C+ ++L+ LR+REW+DV++QL +E G++LN+ P + Sbjct: 571 NLWHYIGQQQKALTSN-QFRRQCKLDYLNYLRVREWQDVYTQLHQSTREMGFKLNDEPGS 629 Query: 635 YDQLHLALLTGLLGNVGFKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTAR 694 Y +H A+L GLL ++G K ++ +Y GAR +FNI+P + L KK +WVM+AELV+T++ Sbjct: 630 YHAVHSAILVGLLSHIGMKDQEKNEYHGARNARFNIFPASGLFKKQPKWVMSAELVETSK 689 Query: 695 LYARCVANIQPEWLEKLGGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYG 754 L+AR VA I+P+W+E L HL K+S+ EP W K+ A V A E+ LYG+ + +R +NYG Sbjct: 690 LWARVVAKIEPDWIEPLAKHLSKRSYSEPHWSKKNAAVMAYEKVMLYGIPIVPKRLVNYG 749 Query: 755 KINPAEAREIFIRDALVGGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGF 814 I+P +REIFIR ALV GD+ET+ FF N+ L+ E+E LEHKSRR D+LVDDE + F Sbjct: 750 TIDPVLSREIFIRSALVEGDWETKHAFFKQNRALLAEVEELEHKSRRRDILVDDEELFQF 809 Query: 815 YDKLIPHDICNGVDFEKWHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIA 874 YD+ + ++ +G F+ W K A+ P LL ++ L + +A+ +T +P + + Sbjct: 810 YDQRVGTEVVSGRHFDAWWKTASRKTPDLLSFEKEMLFKGDASHITDLDYPNFWHQGNLK 869 Query: 875 MALSYHFEPGAARDGVTLTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHC 934 + LSY FEPG DGVT+ +PL LNQV +W +PG+ E V L+KSLP+ LR++ Sbjct: 870 LKLSYQFEPGENSDGVTVHIPLPILNQVEPHGFDWQIPGLRHELVVSLIKSLPKTLRKNF 929 Query: 935 VPLPDYAARFCERMEERKTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFK 994 VP P+YA F R+ T L+DA+ ++R + V D+K + L AH + ++ Sbjct: 930 VPAPNYADAFLARV----TPFEMPLLDAMEKELRRMTGVTVLREDWKLDQLPAHLKITYR 985 Query: 995 IVDEHGRQLEMGRNLAALQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGG 1054 VD R+L +L L+ +++ Q+ QVA D+D Sbjct: 986 AVDHRNRKLNESCDLHELKESL----KEKVQETLSQVA-----DDDI------------- 1023 Query: 1055 TSAAPAAAAPASVGEYSNLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLE 1114 E +L +WSFGELP++ + RG + + +PALVD+K +++ Sbjct: 1024 --------------EQRDLHTWSFGELPKVYQQKRGGFE----VRAYPALVDKKDSVEIK 1065 Query: 1115 VFDDPAEAARFHYAGLRRLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILN 1174 +F+ E AG RRL L + +KYL N+P ++G+ F G +L + + Sbjct: 1066 LFETEQEQLSAMRAGQRRLILLNVPSPIKYLHANLPNKSKLGLYFNPYGKVLDLIDDCIA 1125 Query: 1175 AGLERAFLQ-DPLPRNADEFNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQGIK 1233 G+++ + + F ++ +A LG V EIA+ IL + + K+L+G Sbjct: 1126 CGVDKLIEERGGMVWEPQAFEALKEHVRAELGDTVVEIAKQVETILTTAYNINKRLKGKV 1185 Query: 1234 --AHAQAAADMQAQLSQLVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLL 1291 A A +D++AQ+ L+ F E + L RY++AI R++KL DP +D + Sbjct: 1186 DFTMAFALSDVKAQIEGLIFSGFATECGWKRLPDILRYMRAIERRMEKLPVDPNKDRLHM 1245 Query: 1292 AEWNSVALPYQRAL-KDRAGRADP-KMTEFRWMLEELRVSLYAQELKTPMPVSVKRL 1346 + SVA Y+ L K G A P + E RWMLEELRVS +AQ+L TP PVS KR+ Sbjct: 1246 LKIESVANKYKELLNKIPKGMAIPDNVREIRWMLEELRVSYFAQQLGTPYPVSDKRI 1302 >PM0769 [L] COG1643 HrpA-like helicases Pmu Pasteurella multocida Length = 1304 Score = 1096 bits (2835), Expect = 0.0, Method: Compositional matrix adjust. Identities = 581/1310 (44%), Positives = 827/1310 (63%), Gaps = 91/1310 (6%) Query: 50 RNPLPPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGL 109 ++ + + FPE LPVS R+ EI + HQV++++GETGSGKTTQLPK+CLE GRG KGL Sbjct: 71 KSAVKTIEFPENLPVSQRKAEIQKLISQHQVVVIAGETGSGKTTQLPKMCLEFGRGTKGL 130 Query: 110 IGHTQPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQT 169 IGHTQPRRIAA S A RIA+EL + G+LVGYKVRFND +S +KLMTDGILLAE Q Sbjct: 131 IGHTQPRRIAARSVATRIAEELKTELGDLVGYKVRFNDQISDNTMVKLMTDGILLAEIQN 190 Query: 170 DPLLRQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRE 229 D L QYDT+IIDEAHERSLN DF+LGYLKQLLPKRPDLK+IITSATID +RF++HF Sbjct: 191 DRFLNQYDTLIIDEAHERSLNNDFILGYLKQLLPKRPDLKVIITSATIDVERFSKHFNN- 249 Query: 230 VKGEIVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQR 289 AP+IEVSGR YPVE+RYRP+ + E++ Sbjct: 250 -------APIIEVSGRTYPVEVRYRPV---------------------------VENEEQ 275 Query: 290 DLMDAVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQ 349 D + A++DAVDEL G GD+L+F+ GEREIRD AEAL+K H EILPLFARLSAQEQ Sbjct: 276 DQLQAILDAVDELQAEGRGDILIFMNGEREIRDTAEALQKQDLKHTEILPLFARLSAQEQ 335 Query: 350 ERVFKTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSA 409 ++F S RIVLATNVAETSLTVPGI+YV+D G AR+ RYSYR KV++L IEP++Q++ Sbjct: 336 NKIFHPSGLNRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS 395 Query: 410 ANQRAGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFP 469 ANQR GRCGRV+ G+CIRLY E+DF RP+FTDPEILR++LASVIL+M +L L D+++FP Sbjct: 396 ANQRKGRCGRVSEGICIRLYSEEDFNSRPEFTDPEILRTNLASVILQMTALGLDDIDAFP 455 Query: 470 FIEPPLGRAIADGYQLLQELGAVE----EHGGVNRLTPLGKQLARLPLDPRVGRMILAGR 525 F++ P R I DG +LL+EL A + G +LT GKQLA+LP+DPR+ +M+L Sbjct: 456 FVDAPDKRNIQDGIKLLEELEAFHFVKTKFGEKRQLTQQGKQLAQLPVDPRLAKMLLTAV 515 Query: 526 DNACLTELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIA 585 CL E++II +A+S+QDPR+RP + Q +AD+ H++FAD+KS+F ++L +W++ + Sbjct: 516 KLNCLHEVMIIVSALSIQDPRERPQEKQQSADDKHRRFADKKSDFLAFLNLWQFIQTQ-Q 574 Query: 586 HKKSNRQLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTG 645 S Q + C++++L+ LR+REW+D++ Q+ V+E G +N A Y Q+H ALL+G Sbjct: 575 KALSKNQFRRLCQKDYLNYLRIREWQDIYHQIRLTVREMGLPINSQAAEYAQIHTALLSG 634 Query: 646 LLGNVGFKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQP 705 LL ++G K + +QYLGAR F I+P + L KK +WVMAAELV+T+RL+ R VA+I+P Sbjct: 635 LLSHIGMKENEKSQYLGARNAHFAIFPNSVLFKKQPKWVMAAELVETSRLWGRMVADIEP 694 Query: 706 EWLEKLGGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIF 765 EW+E L HL+KKS+ EPRW K V A E+ +LYG+ + + R +NYG I+P +REIF Sbjct: 695 EWIEPLALHLVKKSYAEPRWSKSKGAVLADEKVSLYGVPIVASRPVNYGSIDPLLSREIF 754 Query: 766 IRDALVGGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICN 825 I+ ALV GD+ T+ FF N++L++EIE+LEHKSRR D+LVD+ + FYD+ I ++ + Sbjct: 755 IQSALVEGDWFTKHKFFHQNRQLIKEIEDLEHKSRRRDILVDERTLFDFYDQRISTEVVS 814 Query: 826 GVDFEKWHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGA 885 F+ W K+ + DP+LL + L + A V+ FP + + L+Y FEPG Sbjct: 815 QRHFDSWWKKVSQQDPELLNFEKAFLTKENAEQVSELDFPNFWHQGNLKFKLTYQFEPGT 874 Query: 886 ARDGVTLTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFC 945 DGVT+ +PL LNQV +W +PG+ KE + L+KSLP+ LRR+ VP P+YA F Sbjct: 875 DADGVTVHIPLPLLNQVEMTGFDWQIPGLRKELIIALIKSLPKALRRNFVPAPNYADAFL 934 Query: 946 ERMEERKTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEM 1005 R + + L++++I ++R + V+ +++ + L +H M F+++D+ G+++ Sbjct: 935 GRAKPLEK----PLLESLIYELRRMTGVTVEAENWQLDQLPSHLKMTFRVIDDKGKKIAE 990 Query: 1006 GRNLAALQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPA 1065 +L +L+ + Q ++ +A G Sbjct: 991 SMDLDSLKFQLKDQVQESI-----------------------SAVADDGI---------- 1017 Query: 1066 SVGEYSNLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARF 1125 E S + W+F LP+ E K+ T+ FPA+VD K +++F+ E Sbjct: 1018 ---EQSGIHVWNFDSLPQCYE----QKKRGFTVKAFPAIVDEKEAVGIKLFETEFEQQVA 1070 Query: 1126 HYAGLRRLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQ-D 1184 GLRRL L + +KYL + +P ++G+ F G +L + + +++ ++ Sbjct: 1071 MQQGLRRLLLLNVPSPIKYLHEKLPNKSKLGLYFTPFGRVLDLIDDCIACAVDKLVVEFG 1130 Query: 1185 PLPRNADEFNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQGIK--AHAQAAADM 1242 L N +F++ RD + L EIA+ QIL + L K+L+G A A +D+ Sbjct: 1131 GLVWNEADFDKLRDFIRENLNETTEEIAKQVEQILTLTYELNKRLKGKMDFTMAFALSDI 1190 Query: 1243 QAQLSQLVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQ 1302 +AQL+ L+ + FV +T Y L+ RYL+AI+ R+DKL D RD + V+ YQ Sbjct: 1191 KAQLNGLIYQGFVQKTGYTRLNDLQRYLQAIDKRIDKLLQDVNRDRAAMLRVEQVSQAYQ 1250 Query: 1303 RALKDRAGRADPKMTEFR---WMLEELRVSLYAQELKTPMPVSVKRLQKV 1349 + L + ++ P E + +M+EELRVSL+AQ+L T P+S KR+ V Sbjct: 1251 QLLA-KLPKSKPHSDEVKEIPYMIEELRVSLFAQQLGTKYPISDKRILNV 1299 >HI1070 [L] COG1643 HrpA-like helicases Hin Haemophilus influenzae Length = 1304 Score = 1065 bits (2754), Expect = 0.0, Method: Compositional matrix adjust. Identities = 578/1306 (44%), Positives = 808/1306 (61%), Gaps = 92/1306 (7%) Query: 55 PVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGLIGHTQ 114 P+ FPE LPVS R+ EI + HQVI+V+GETGSGKTTQLPK+CLELG G G+IGHTQ Sbjct: 76 PIVFPESLPVSQRKVEIQKLISEHQVIVVAGETGSGKTTQLPKMCLELGFGNLGMIGHTQ 135 Query: 115 PRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQTDPLLR 174 PRRIAA S A RIA+EL + G LVGYKVRFND +S IKLMTDGILLAE Q D L Sbjct: 136 PRRIAARSVAARIAEELETELGGLVGYKVRFNDQISDNTQIKLMTDGILLAEIQNDRFLN 195 Query: 175 QYDTIIIDEAHERSLNIDFLLGYLKQLLPKRP-DLKIIITSATIDADRFARHFGREVKGE 233 QY +IIDEAHERSLN DF+LGYLKQLLP+R DLK+IITSATID +RF++HF Sbjct: 196 QYSCLIIDEAHERSLNNDFILGYLKQLLPRRRRDLKLIITSATIDVERFSKHFNN----- 250 Query: 234 IVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQRDLMD 293 AP+IEVSGR YPVE+RYRP+ D +D + Sbjct: 251 ---APIIEVSGRTYPVEVRYRPVVEED---------------------------DQDQLQ 280 Query: 294 AVVDAVDELARIGAGDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFARLSAQEQERVF 353 +++AVDEL G GD+L+F+ GEREIRD AEAL+K + H EILPLFARLSAQEQ ++F Sbjct: 281 GILNAVDELQAEGRGDILIFMNGEREIRDTAEALQKQNLKHTEILPLFARLSAQEQNKIF 340 Query: 354 KTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIEPVAQSAANQR 413 S RIVLATNVAETSLTVP I+YV+D G AR+ RYSYR KV++L IEP++Q++ANQR Sbjct: 341 HPSGLNRIVLATNVAETSLTVPSIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQR 400 Query: 414 AGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLTDVESFPFIEP 473 GRCGRV+ G+CIRLY E+DF RP+FTDPEILR++LASVIL+M +L L D+E+FPF++ Sbjct: 401 KGRCGRVSEGICIRLYSEEDFNSRPEFTDPEILRTNLASVILQMTALGLDDIEAFPFVDA 460 Query: 474 PLGRAIADGYQLLQELGAVE----EHGGVNRLTPLGKQLARLPLDPRVGRMILAGRDNAC 529 P R I DG +LL+ELGA E + G LT +G+QLA+LP+DPR+ +MIL+ + C Sbjct: 461 PDERHIQDGVKLLEELGAFETVQTKSGEKRLLTRVGRQLAQLPVDPRLAKMILSAVNFGC 520 Query: 530 LTELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDAIAHKKS 589 + E++II +A+S+QDPR+RP + Q A+D H++FAD+KS+F ++L +W++ ++ + S Sbjct: 521 VYEMMIIVSALSIQDPRERPQEKQQASDEKHRRFADKKSDFLAFLNLWRYLQEQ-QKESS 579 Query: 590 NRQLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLNEAPATYDQLHLALLTGLLGN 649 Q + C+++FL+ LR+REW+D++ Q+ V+E +N A Y Q+H ALL+GLL + Sbjct: 580 KNQFRRQCQKDFLNYLRIREWQDIYHQIRLTVREMSLPINSEKAEYQQIHTALLSGLLSH 639 Query: 650 VGFKSEDDAQYLGARGIKFNIWPGAHLTKKPGRWVMAAELVDTARLYARCVANIQPEWLE 709 +G K + QYLGAR F I+P + L KK +WVMAAELV+T++L+ R VA I+PEW+E Sbjct: 640 IGLKEAEKQQYLGARNAHFAIFPNSVLFKKQPKWVMAAELVETSKLWGRMVAEIEPEWIE 699 Query: 710 KLGGHLLKKSWGEPRWEKRAAQVTASERATLYGLVVYSQRRINYGKINPAEAREIFIRDA 769 L HL+KKS+ P W K V A E+ TLYG+ + + R +NYG I+P +REIFI+ A Sbjct: 700 PLAEHLIKKSYSVPLWSKSRGAVIADEKVTLYGVPIVAVRPVNYGAIDPTVSREIFIQSA 759 Query: 770 LVGGDFETRAPFFAHNQKLVREIENLEHKSRRLDVLVDDELIIGFYDKLIPHDICNGVDF 829 LV G + T+ FF NQ+LVRE+E LEHKSRR D+LVDD + FYD+ I ++ + F Sbjct: 760 LVEGGWNTKHKFFKENQRLVREVEELEHKSRRRDILVDDRTLFEFYDQRIGTEVVSQKHF 819 Query: 830 EKWHKEATAADPKLLYLNRDDLMRHEAAGVTTELFPKTMNVAGIAMALSYHFEPGAARDG 889 + W K+A DP+LL L+ +A V+ FP + + + L+Y FEPG DG Sbjct: 820 DTWWKKAQQKDPELLNFEHSFLINDDAEQVSKLDFPNFWHQGNLKLKLTYQFEPGTDADG 879 Query: 890 VTLTVPLYALNQVSADRCEWLVPGMLKEKVHLLLKSLPQKLRRHCVPLPDYAARFCERME 949 VT+ +PL LNQV +W +PG+ +E V L+KSLP+ RR+ VP P+YA F R Sbjct: 880 VTVHIPLPLLNQVEMTGFDWQIPGLREELVIALIKSLPKSYRRNFVPAPNYAQAFLSRAV 939 Query: 950 ERKTFGRGNLIDAIIADIREQITLLVKPSDFKQETLSAHHAMNFKIVDEHGRQLEMGRNL 1009 + L+D +I ++R + V+ + E + +H M F++VDE+G+++ NL Sbjct: 940 PLEK----PLLDTLIYELRRMTGVTVEAEHWNWEQIPSHLKMTFRVVDENGKKIAESMNL 995 Query: 1010 AALQAEFGGQARQQFQKLAEQVAIAPREDEDNAAPSPAAATGKGGTSAAPAAAAPASVGE 1069 L+ +D S +A G E Sbjct: 996 DELKFNL----------------------KDRVQESISAVADDG--------------IE 1019 Query: 1070 YSNLTSWSFGELPELLEITRGSGKQAQTLIGFPALVDRKTHCDLEVFDDPAEAARFHYAG 1129 S L WSF +LP+ E ++ ++ FPA+VD K +++F+ E + G Sbjct: 1020 QSGLHIWSFADLPQCYE----QKQRGFSVKAFPAIVDEKDAVGIKLFETEFEQSVAMQQG 1075 Query: 1130 LRRLFALQMKEQLKYLEKNIPGLQQMGMQFMALGSQEELREQILNAGLERAFLQDPLPRN 1189 LRRL L + +KYL + +P ++G+ F G +L + + +++ + D Sbjct: 1076 LRRLLLLNVPSPIKYLHEKLPNKAKLGLYFTPFGRVLDLIDDCIACAVDK-LIADFGGFV 1134 Query: 1190 ADE--FNRRRDEGKARLGLLVNEIARLCGQILAEYHALPKKLQGIK--AHAQAAADMQAQ 1245 DE F + RD + L + +IA+ QIL + L ++L+G A A +D+++Q Sbjct: 1135 WDEAGFEKLRDFVRENLNEVTVDIAQKVEQILTLTYQLNQRLKGKMDFTMAFALSDIKSQ 1194 Query: 1246 LSQLVGKRFVAETDYGNLSHYPRYLKAINVRLDKLRADPARDTRLLAEWNSVALPYQRAL 1305 L+ LV + FV ++ Y L RYL+A++ R+DKL D RD + V YQ+ L Sbjct: 1195 LAGLVYQGFVQKSGYDRLPDLQRYLQAVDKRIDKLAQDVNRDRAAMLRVEQVQQAYQQLL 1254 Query: 1306 KD--RAGRADPKMTEFRWMLEELRVSLYAQELKTPMPVSVKRLQKV 1349 ++ ++ E R+M+EELRVSL+AQ+L T +S KR+ + Sbjct: 1255 AKLPKSKPISDEVAEIRYMIEELRVSLFAQQLGTKYQISDKRIGNI 1300 >PA3297 [L] COG1643 HrpA-like helicases Pae Pseudomonas aeruginosa Length = 1326 Score = 1043 bits (2696), Expect = 0.0, Method: Compositional matrix adjust. Identities = 608/1342 (45%), Positives = 815/1342 (60%), Gaps = 113/1342 (8%) Query: 50 RNPLPPVTFPEELPVSGRRHEIAAALRAHQVIIVSGETGSGKTTQLPKICLELGRGEKGL 109 R +P + + + LP++ +R EI AA+ AHQV++++GETGSGKTTQLPKICLELGRG GL Sbjct: 60 RASVPAIRYDDSLPIAAKRDEIKAAIAAHQVVVIAGETGSGKTTQLPKICLELGRGIHGL 119 Query: 110 IGHTQPRRIAASSTAKRIAQELNSPPGELVGYKVRFNDTLSKGAWIKLMTDGILLAETQT 169 IGHTQPRR+AA S A R+A+E+ +P G LVGY+VRF D +KLMTDGILLAETQ Sbjct: 120 IGHTQPRRLAARSVATRVAEEIGTPLGALVGYQVRFEDQSDDSTLVKLMTDGILLAETQH 179 Query: 170 DPLLRQYDTIIIDEAHERSLNIDFLLGYLKQLLPKRPDLKIIITSATIDADRFARHFGRE 229 D L +YDT+I+DEAHERSLNIDFLLGYLK LL +RPDLK+IITSATID +RF+RHF Sbjct: 180 DRYLERYDTLIVDEAHERSLNIDFLLGYLKTLLHRRPDLKLIITSATIDLERFSRHFD-- 237 Query: 230 VKGEIVPAPVIEVSGRLYPVEIRYRPIDNADRSGVSTEVAQARARAEGRASQAQKDREQR 289 APVIEVSGR YPVE YRP+ + E + R E S Q Sbjct: 238 ------GAPVIEVSGRTYPVETWYRPL--------AAETDEEGNRVEDDLSVDQ------ 277 Query: 290 DLMDAVVDAVDELA----RIGA--GDVLVFLPGEREIRDAAEALRKHHPPHVEILPLFAR 343 ++ A+DE+A +G GDVLVFLPGEREIRDAAE LRK + H E+LPL+AR Sbjct: 278 ----GILAALDEIAAHEREVGKRPGDVLVFLPGEREIRDAAEMLRKANLRHTEVLPLYAR 333 Query: 344 LSAQEQERVFKTSNARRIVLATNVAETSLTVPGIRYVVDAGLARVKRYSYRNKVEQLQIE 403 L+ EQ+++F+ R+IVL+TNVAETSLTVPGIRYV+D+G AR+ RYSYR KV++L IE Sbjct: 334 LTPAEQQKIFQPRPGRKIVLSTNVAETSLTVPGIRYVIDSGTARISRYSYRAKVQRLPIE 393 Query: 404 PVAQSAANQRAGRCGRVAAGVCIRLYDEQDFLQRPKFTDPEILRSSLASVILRMKSLHLT 463 V+Q++ANQR GRCGRV G+C+RLY E+DF RP FTDPEILR++LA+VIL+M L L Sbjct: 394 AVSQASANQRKGRCGRVEPGICVRLYSEEDFNARPAFTDPEILRTNLAAVILQMLHLRLG 453 Query: 464 DVESFPFIEPPLGRAIADGYQLLQELGAVEEHGGVNRLTPLGKQLARLPLDPRVGRMILA 523 D+E+FPFIEPP G+AI DG+ LLQEL AV G +LTPLG+QLARLP+DPR+GRM+L Sbjct: 454 DIEAFPFIEPPDGKAIKDGFTLLQELSAVNREG---QLTPLGRQLARLPIDPRLGRMLLE 510 Query: 524 GRDNACLTELLIIAAAVSVQDPRDRPMDAQNAADNAHKKFADEKSEFASYLKIWKWFEDA 583 L E+L +A+A+SVQDPR+RP++ Q AAD AH ++ D S+FA+ + +W+ FE+ Sbjct: 511 AAQQGSLEEVLTVASALSVQDPRERPVERQQAADQAHAQWKDPDSDFAALINLWRGFEEQ 570 Query: 584 IAHKKSNRQLQEHCRENFLSQLRLREWRDVHSQLLTIVKEQGWRLN-------------- 629 SN L+ CR+NFL+ LRLREWRD H QL I +E Sbjct: 571 RQALGSN-ALRSWCRKNFLNYLRLREWRDAHRQLTLICRELKLPFGRPAKAEARKPEAKK 629 Query: 630 --------EAPAT-YDQLHLALLTGLLGNVGFKSEDDAQYLGARGIKFNIWPGAHLTKKP 680 E P Y +H A+L+GLL +G K+E+ YLGAR +F I P + + +K Sbjct: 630 GASADNEREVPGIDYAAVHKAILSGLLSQIGQKAEE-GDYLGARQRRFWIHPSSGIARKR 688 Query: 681 GRWVMAAELVDTARLYARCVANIQPEWLEKLGGHLLKKSWGEPRWEKRAAQVTASERATL 740 +W+MAAELV+T +L+AR VA I+P+WLE L GHL+K + EP WEKR QV A E+ TL Sbjct: 689 PQWIMAAELVETTKLFARMVAKIEPDWLEPLAGHLIKTNHFEPHWEKRRGQVVAFEQVTL 748 Query: 741 YGLVVYSQRRINYGKINPAEAREIFIRDALVGGDFETRAPFFAHNQKLVREIENLEHKSR 800 YGL+V +R ++YG I+P ARE+FIR+ LV G+ +RA + N++L+ +++ LE K+R Sbjct: 749 YGLIVIGRRPVHYGPIDPPVARELFIREGLVRGEINSRAKCLSANRQLLEKLDELEAKAR 808 Query: 801 RLDVLVDDELIIGFYDKLIPHDICNGVDFEKWHKEATAADPKLLYLNRDDLMRHEAAGVT 860 R D+L D+E + +YD +P DI FEKW+ P LL + +D++ EA+ VT Sbjct: 809 RRDILADEETLFAYYDARLPADIYQTASFEKWYARERQNQPDLLLMREEDVLAREASEVT 868 Query: 861 TELFPKTMNVAGIAMALSYHFEPGAARDGVTLTVPLYALNQVSADRCEWLVPGMLKEKVH 920 +P + + + ++LSY FEPG ARDGVT+ VP L Q+ A+R +WLVPG+L +K Sbjct: 869 AAQYPDRLRLGDLHLSLSYQFEPGTARDGVTVRVPAPLLPQLPAERIDWLVPGLLYDKAV 928 Query: 921 LLLKSLPQKLRRHCVPLPDYAARFCERMEERKTFGRGNLIDAIIADIREQITLLVKPSDF 980 L+++LP+ +R+ VP+PD+ ER+ TFG G+L + +++ + V + Sbjct: 929 ALVRNLPKAIRKSFVPVPDFVRAALERI----TFGEGSLPQVLGRELQRMTGVRVADEAW 984 Query: 981 KQET--LSAHHAMNFKIVDEHGRQLEMGRNLAALQAEFGGQARQQFQKLAEQVAIA-PRE 1037 + L H MN ++VD G+ L GR+LA L A F A Q A+A P+ Sbjct: 985 AEAATQLDDHLRMNIEVVDAQGKFLGEGRDLAELTARFAE---------ASQAALAIPQA 1035 Query: 1038 DEDNAAPSPAAATGKGGTSAAPAAAAPASVGEYSNLTSWSFGELPELLEITRGSGKQAQT 1097 D++ P A A ASV E + + Sbjct: 1036 DKEQQRPVEAKAF--------------ASVAEKAQQKVAGL------------------S 1063 Query: 1098 LIGFPALVDRKTHCDLEVFDDPAEAARFHYAGLRRLFALQMKEQLKYLEKNIPGLQQMGM 1157 + +PALV+ + F AEA H L+RL Q+ E KYL +PG +MG+ Sbjct: 1064 MTVYPALVEEQGEVKEGRFPTQAEADYQHRRALQRLLLQQLAEPAKYLRAKLPGQTEMGL 1123 Query: 1158 QFMALGSQEELREQILNAGLERAFLQ-DPLPRNADEFNRRRDEGKARLGLLVNEIARLCG 1216 + LG E L E IL A L+ LQ + LPR+ + +A +ARL Sbjct: 1124 LYRELGRVEALVEDILLASLDSCVLQGESLPRDGAALAALAERKRAAWNEHAERLARLVL 1183 Query: 1217 QILAEYHALPKKLQGIKAHAQAAA--DMQAQLSQLVGKRFVAETDYGNLSHYPRYLKAIN 1274 IL +H L K+ +G A D++ QL+ LV FV T L YPRYLKAI Sbjct: 1184 DILKLWHGLQKRFKGKVELAMTVPLNDVKGQLANLVYPGFVRATPLEWLKEYPRYLKAIE 1243 Query: 1275 VRLDKLRADPARDTRLLAEWNSVALPYQRALKDRA--GRADPKMTEFRWMLEELRVSLYA 1332 RLDK+ RD E + YQ L A G+ D ++ +RWMLEE RVSL+A Sbjct: 1244 QRLDKVAGQVQRDRVWSGELGELWAQYQARLAKHAQEGKRDAELQVYRWMLEEYRVSLFA 1303 Query: 1333 QELKTPMPVSVKRLQKVWESMQ 1354 Q+L T +PVS KRL K W ++ Sbjct: 1304 QQLGTRLPVSDKRLAKQWSQVE 1325