BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0038.p (296 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5466 [R] COG0679 Predicted permeases Pae Pseudomonas aeruginosa 130 3e-30 RSc1095 [R] COG0679 Predicted permeases Rso Ralstonia solanacearum 130 4e-30 RC0506 Non COG 118 2e-26 RP372 [R] COG0679 Predicted permeases Rpr Rickettsia prowazekii 114 3e-25 SMc01358 [R] COG0679 Predicted permeases Sme Sinorhizobium meliloti 107 3e-23 VCA0024 [R] COG0679 Predicted permeases Vch Vibrio cholerae 91 3e-18 FN0623 [R] COG0679 Predicted permeases Fnu Fusobacterium nucleatum 84 5e-16 PM0712 [R] COG0679 Predicted permeases Pmu Pasteurella multocida 81 3e-15 YPO3791 [R] COG0679 Predicted permeases Ype Yersinia pestis 77 4e-14 YPO2874 [R] COG0679 Predicted permeases Ype Yersinia pestis 74 3e-13 >PA5466 [R] COG0679 Predicted permeases Pae Pseudomonas aeruginosa Length = 314 Score = 130 bits (328), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 105/290 (36%), Positives = 156/290 (53%), Gaps = 12/290 (4%) Query: 7 LLPDFSLIALGVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTGGLVQ 66 L P F+LI G + R G+ FW E+L YF+LFPALLF + A +D GL + Sbjct: 18 LWPLFALIVGGYALRRWDFPGEAFWPAAERLNYFILFPALLFSNLATAPLD---DPGLAR 74 Query: 67 TGLLALLAGIALTWLG----KPFLRSTPMTYESGMQCAYRFNSYIALALATRMAGEEGAG 122 L A+L G+ + WL K + + + Q RFN+Y+ LA + G+ G Sbjct: 75 QAL-AVLLGLGVAWLALLLCKRWRGWDAGRFGAIAQGVLRFNTYLGLAAVGSLYGKPGLT 133 Query: 123 LMAILLGFGVPLCNIAAVHALAPKNSNLLRELA----KNPLLVATAGGLTFSALGLHLPE 178 L A++L VP N+ +V AL + LR L KNPL++A G + G+ LP Sbjct: 134 LAALMLALMVPTVNVMSVWALTAERGISLRALLLPILKNPLILACLAGALVNLAGVGLPG 193 Query: 179 VAGVVLSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVFIKLFAVPAVAWLIGQHLQ 238 + +L+ L AS+ LGLL VGA L+ L +GW +L A+P +A+ I + L Sbjct: 194 GSDRLLNLLAVASLPLGLLCVGAALKPQELGGEVAALGWNCAARLLAMPLLAFAIARGLG 253 Query: 239 LPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTLLSALTI 288 LP ++ ++VLF +LPTA +AY+L ++GG+G A +I+ TLLS T+ Sbjct: 254 LPSMESAVLVLFFALPTAPTAYVLTRQLGGDGHLMAGIITLQTLLSGATL 303 >RSc1095 [R] COG0679 Predicted permeases Rso Ralstonia solanacearum Length = 310 Score = 130 bits (327), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 94/286 (32%), Positives = 149/286 (52%), Gaps = 20/286 (6%) Query: 17 GVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTGGLVQTGLLALLAGI 76 G L+ R D FW E+L Y++L PAL +S A V S+ + L+ A + Sbjct: 19 GHLIRRTGFVADAFWPQAERLCYYILLPALFMHSLATAHVQ-SLQVAALACALIGSTAMV 77 Query: 77 ALTWLG-KPFLRSTPMTYESGMQCAYRFNSYIALALATRMAGEEGAGLMAILLGFGVPLC 135 AL + +P L+ + S Q A RFN+Y+ ++LA + G +G L A+ VP Sbjct: 78 ALMVVAARPLLKVDGAAFTSVFQGAIRFNNYVGVSLAAGLFGAKGVALAAVCNAAIVPSV 137 Query: 136 NIAAVHALAP------KNSNLLRELAKNPLLVATAGGLTFSALGLHLPEVAGVVLSRLGA 189 N+ V A + + ++R++ NPL+VA GG+ G+ +P + + LG+ Sbjct: 138 NLMCVLVFARYGSVRLRGAAVVRQIVTNPLVVACVGGIALQVGGIEIPAIVEPAVRALGS 197 Query: 190 ASIALGLLMVGAGLRLSGLKESKPVVGWFVFI------KLFAVPAVAWLIGQHLQLPPLQ 243 AS+ LGLL VGA L L ES+ WF I K +P ++I + + L + Sbjct: 198 ASMPLGLLCVGAALNLG---ESR---SWFGPICVSSAFKFLLMPVSTFMIARMVGLGEVA 251 Query: 244 LRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTLLSALTIP 289 + + +LF +LPTASS+YI+A ++GG+ P A + + T+L+AL IP Sbjct: 252 MTVALLFQALPTASSSYIMARQLGGDAPLMAGITAAQTMLAALAIP 297 >RC0506 Non COG Length = 310 Score = 118 bits (295), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 93/304 (30%), Positives = 154/304 (50%), Gaps = 21/304 (6%) Query: 2 EILNLLLPDFSLIALGVLVYRISNW--GDEFWAGMEKLVYFLLFPALLF--YSTARLKVD 57 EI LP F + LG ++ W +EFW G+EKL YF+LFPA+LF STA L + Sbjct: 3 EIFCSTLPIFLITLLGSIIKN--KWLTSEEFWRGIEKLSYFVLFPAMLFSYVSTADLSIA 60 Query: 58 LSVTGGLVQTGLLALLAGIALTWLGKPFLRSTPMTYESGMQCAYRFNSYIALALATRMAG 117 + +V + +L I L K + + + S Q + R+NSYI +++ + G Sbjct: 61 -PIIKLVVALIISTILVSIGLIIYQKKY-NIDKVQFTSIFQGSIRYNSYIFFGVSSPLLG 118 Query: 118 EEGAGLMAILLGFGVPLCNIAAVHALA---PKNSN----------LLRELAKNPLLVATA 164 G ++AI+ + + NI +V A P S +++ + +NPL++A+ Sbjct: 119 SSGLSIVAIISSYMIIFTNILSVMIFAYYIPNKSVTNTISTSFVLMMKLIVRNPLIIASL 178 Query: 165 GGLTFSALGLHLPEVAGVVLSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVFIKLF 224 G F+ L L L L A++A+G+L VGAGL + +E V + F+KL Sbjct: 179 VGFVFNYSNLELHLGLKKTLDSLSNAALAIGMLNVGAGLNFTIRQELLHNVMFTSFVKLV 238 Query: 225 AVPAVAWLIGQHLQLPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTLLS 284 A P V+ ++ + + L + +L+ LP AS+AY+L+ ++ G+ A +I+F T S Sbjct: 239 AFPLVSVVVLWLMSIDGLDRSVGILYSCLPCASTAYVLSRQLDGDPDSMASIITFTTFFS 298 Query: 285 ALTI 288 +TI Sbjct: 299 VVTI 302 >RP372 [R] COG0679 Predicted permeases Rpr Rickettsia prowazekii Length = 323 Score = 114 bits (285), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 98/315 (31%), Positives = 158/315 (50%), Gaps = 29/315 (9%) Query: 2 EILNLLLPDFSLIALGVLVYRISNW--GDEFWAGMEKLVYFLLFPALLF--YSTARLKVD 57 EI LP F + LG ++ + W +E W G+EKL YF+LFPA+LF STA D Sbjct: 16 EIFCSTLPIFLITLLGSIIK--NKWLTSEEVWRGIEKLSYFILFPAMLFNYVSTA----D 69 Query: 58 LSVTGGLVQTGLLALLAGIALTWLG----KPFLRSTPMTYESGMQCAYRFNSYIALALAT 113 LSVT + ++AL+ L LG + + + S Q + R+NSYI +++ Sbjct: 70 LSVTS--IIKLVVALIISTILVSLGLIIYQKKCNIDKVQFTSIFQGSIRYNSYIFFGVSS 127 Query: 114 RMAGEEGAGLMAILLGFGVPLCNIAAVHALA---PKNS--NLLRE--------LAKNPLL 160 + G G ++A++ + + NI + A P S N LR + +NPL+ Sbjct: 128 PLLGPSGLSIVAVISSYMIIFTNILSAMIFAYYIPNKSVTNTLRTSFVLMMKLIIRNPLI 187 Query: 161 VATAGGLTFSALGLHLPEVAGVVLSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVF 220 +A+ G F+ L L L L A++A+G+L VGAGL + +E V F Sbjct: 188 IASLVGFIFNYSNLELYLGLKKTLDSLSNAALAIGMLNVGAGLNFTIRQELLHNVMLTSF 247 Query: 221 IKLFAVPAVAWLIGQHLQLPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFG 280 IKL A P V+ ++ + + + + +L+ LP AS+AY+L+ ++ G+ A +I+F Sbjct: 248 IKLVAFPLVSVIVLWLMSIEGINRSVGILYSCLPCASTAYVLSRQLDGDPDSMASIITFT 307 Query: 281 TLLSALTIPFWLALV 295 T S +TI + L+ Sbjct: 308 TFFSVITISIIMYLM 322 >SMc01358 [R] COG0679 Predicted permeases Sme Sinorhizobium meliloti Length = 311 Score = 107 bits (267), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 98/304 (32%), Positives = 161/304 (52%), Gaps = 27/304 (8%) Query: 7 LLPDFSLIALGVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTAR-----LKVDLSVT 61 +LP F L+ LGV + R + W G+E+ Y+ LFPALLF + A+ L+ D + Sbjct: 8 ILPVFLLVILGVALRRSTLVDQGLWIGLEQFGYYFLFPALLFSTLAKADLAGLEADATAV 67 Query: 62 GGLVQTGLLALLAGIALTWLGKPFLR----STPMTYESGMQCAYRFNSYIALALATRMAG 117 + L++ A + W P LR S P T+ S Q A R+N++IALA+A ++ G Sbjct: 68 ATVGSVTLMS--AALLSAW---PLLRRGGISGP-TFTSVFQTATRWNAFIALAVAEKLFG 121 Query: 118 EEGAGLMAI---LLGFGVPLCNIAAVHALAPKNSNL---LRELAKNPLLVATAGGLTFSA 171 G L A+ LL + NIA + + + ++ NPL++++A G+ F+ Sbjct: 122 TAGLSLTALVMALLIIPINFYNIAVLTWFGGGSRGIGFFFLKIITNPLIISSALGILFNL 181 Query: 172 LGLHLPEVAGVVLSRLGAASIALGLLMVGAGLRLS-GLKESKPVVGWFVFIKLFAVPAVA 230 G+ L E + L +AS+ LGL++VGAGL+++ L S PV+ + V +KL +P Sbjct: 182 TGIELYEPVMTAVDMLASASLGLGLILVGAGLKIADALNPSIPVL-FAVVLKLIVMP--V 238 Query: 231 WLIGQH--LQLPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTLLSALTI 288 +++G L + L ++ + ++PTA + Y+LA +MGG+ A + + T S LTI Sbjct: 239 FMVGSSALLGIRGDALLVIAVGAAVPTAMNGYLLAKQMGGDAELYASVATIQTAASFLTI 298 Query: 289 PFWL 292 P L Sbjct: 299 PLVL 302 >VCA0024 [R] COG0679 Predicted permeases Vch Vibrio cholerae Length = 330 Score = 90.9 bits (224), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 86/289 (29%), Positives = 129/289 (44%), Gaps = 19/289 (6%) Query: 13 LIALGVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTGGLVQTGLLAL 72 ++ LGVL RI+ + F ++V+ + PA+LF S K D S + LV L+A Sbjct: 33 MLGLGVLFKRINLINENFIEVASRIVFQVTLPAMLFLSIVSSKHDFSSSTSLVVYSLIAN 92 Query: 73 LAGIALTWLGKPFLRSTPMTYESGMQCAYRFNS-YIALALATRMAGEEGAGLMAILLGFG 131 + T L P + Q +R N+ I LA G G L AI + Sbjct: 93 MLFFLFTLFSTRKLIDRPHDWGVITQGGFRANTAIIGLAYVANTYGNAGVALAAIYVAST 152 Query: 132 VPLCNIAAVHALAPK-NSN-------LLRELAKNPLLVATAGGLTFSALGLHLPEVAGVV 183 L NI AV AL P+ SN + + L KNPL+++ G + +P++ Sbjct: 153 TVLFNIQAVIALTPRGESNGWQAGKLMFKTLTKNPLIISIVLGFLCYLASVPIPKIVTDA 212 Query: 184 LSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVF-IKLFAVPAV----AWLIGQHLQ 238 ++ L LL G L L+ LK+ + WF KL P + AWL+G Sbjct: 213 GHYFANMTLPLALLCTGGSLNLNSLKDDRHS-AWFATGYKLILSPLLITGGAWLLG---- 267 Query: 239 LPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTLLSALT 287 L L ++ L S PTA+++Y++A MGGN A +I+ T+ S T Sbjct: 268 FRGLDLGLLFLMTSAPTAAASYVMARAMGGNATLAANIIALTTVFSLFT 316 >FN0623 [R] COG0679 Predicted permeases Fnu Fusobacterium nucleatum Length = 318 Score = 83.6 bits (205), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 74/304 (24%), Positives = 146/304 (48%), Gaps = 14/304 (4%) Query: 5 NLLLPDFSLIALGVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTG-- 62 N++ P F ++ LGV++ R S ++ M L++ L P LLF++ + DLS Sbjct: 12 NVVFPIFLIMILGVILKRKSMVDEKSLNVMNSLIFRLFMPTLLFFNIYNMG-DLSTLSFD 70 Query: 63 --GLVQTGLLALLAGIALTWL-GKPFLRSTPMTYESGMQCAYRFNSYI-ALALATRMAGE 118 L+ ++L + L WL P ++ +Q YR N + LA+A + G+ Sbjct: 71 NLKLLAYAFTSILIVLFLAWLIYMPNIKDRK-KLSVLIQGVYRGNFVLFGLAIADSLYGK 129 Query: 119 EGAGLMAILLGFGVPLCNIAAVHALAPKNSN------LLRELAKNPLLVATAGGLTFSAL 172 E G +++L +P N+ AV L + N L++++ KNPL++AT + F L Sbjct: 130 ESLGTVSLLTAIVIPTFNVIAVILLEYYSGNEVNKIKLIKQVFKNPLIIATLTAIVFLVL 189 Query: 173 GLHLPEVAGVVLSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVFIKLFAVPAVAWL 232 +++P+ + + + L L++GAGL+ + ++ + ++L P + Sbjct: 190 KINIPKPVYKAIGDISKIATPLAFLVLGAGLKFGNILKNLKYLISVNILRLIGNPLITVG 249 Query: 233 IGQHLQLPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTLLSALTIPFWL 292 +G+ L ++L ++ + PTA +Y +A M +G +++ ++LS TI W+ Sbjct: 250 LGKLLGFQGIELVALLSMSACPTAVVSYTMAKEMNADGDLAGEIVATTSMLSIFTIFCWV 309 Query: 293 ALVH 296 ++ Sbjct: 310 LMLK 313 >PM0712 [R] COG0679 Predicted permeases Pmu Pasteurella multocida Length = 319 Score = 80.9 bits (198), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 78/291 (26%), Positives = 131/291 (45%), Gaps = 16/291 (5%) Query: 4 LNLLLPDFSLIALGVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTGG 63 +++ LP ++ LGV++ R D+F ++++ + P LLF + VD Sbjct: 14 MSVTLPTVLMLLLGVILKRQRMVDDKFTGQATRIIFNITLPILLFLNITSNPVDFRSQ-- 71 Query: 64 LVQTGLLALLAGIALTWLGKPFL--RSTPMTYESG--MQCAYRFNSYI-ALALATRMAGE 118 ++A + G L +LG + + E G +Q YR N+ I LAL GE Sbjct: 72 --MLPIMASVVGTLLLFLGAELVAGKYIAEKTERGTFVQAVYRGNNGILGLALCINAYGE 129 Query: 119 EGAGLMAILLGFGVPLCNIAAV----HALAPKNSNLLRELA---KNPLLVATAGGLTFSA 171 G +I + L N+ V A A N +L R L +NPL++A G + Sbjct: 130 AGLAPASIYAAATIFLFNVLGVITLSRAFAQGNVSLWRVLNNVLRNPLIIAIVLGYVVNH 189 Query: 172 LGLHLPEVAGVVLSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVFIKLFAVPAVAW 231 L L P+ + L + ++ L L+ GA ++ G+++ VV W ++ P V Sbjct: 190 LELTFPKTLQTTGNYLASMTLPLALICTGASIQFKGMRKDSRVVIWGSIGRVLIAPVVMV 249 Query: 232 LIGQHLQLPPLQLRIVVLFCSLPTASSAYILAARMGGNGPFTAFLISFGTL 282 +G+ L + + I+ L + P A+ AY + MGGNG A +I+ TL Sbjct: 250 FVGKLFGLSGMNMGILFLMAATPMATIAYAMVRGMGGNGVSAANIIALTTL 300 >YPO3791 [R] COG0679 Predicted permeases Ype Yersinia pestis Length = 308 Score = 77.0 bits (188), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 77/285 (27%), Positives = 126/285 (44%), Gaps = 20/285 (7%) Query: 9 PDFSLIALGVLVYRISNWGDEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTGGLVQTG 68 P F L+ALG + R W G+ + V+ L PA+LF R+ D S + Sbjct: 17 PLFVLLALGYALVRFGKWPSTITDGLTRFVFSLALPAMLF----RMMCDFSERPAVDARL 72 Query: 69 LLALLAGIALTWLGKPFL--RSTPMTYESGMQCA----YRFNSYIALALATRMAGEEGAG 122 L+A + ++ + R + SG A + N + L +AT M GE+ Sbjct: 73 LIAFFGSCLVVFIIGRVIAKRVFHLDGVSGSVFALGGIFSNNVMLGLPIATIMLGEKSIP 132 Query: 123 LMAILLGF-GVPLCNIAAVHALAPKNSN--------LLRELAKNPLLVATAGGLTFSALG 173 +A++L F G+ L + + +N + R + NPL++ G FS G Sbjct: 133 AVALVLVFNGLILWTLVTISVEWARNGSPTMAGFVKTTRSVLTNPLIIGIISGTLFSLTG 192 Query: 174 LHLPEVAGVVLSRLGAASIALGLLMVGAGLRLSGLKESKPVVGWFVFIKLFAVPAVAWLI 233 LHLP +S LG + L L+++G GL + E + F+KL P V W + Sbjct: 193 LHLPVFIDQPVSMLGQVAPPLSLIVLGMGLAEYRVTEGWQISTAICFLKLIVQPMVIWAL 252 Query: 234 GQHLQLPPLQLRIVVLFCSLPTASSAYILAARMGG-NGPFTAFLI 277 + LP L+ ++VVL S+ T + Y+++ + GP A L+ Sbjct: 253 AWAMDLPALETQVVVLLGSMATGVNVYLMSRQFNVLTGPAAASLV 297 >YPO2874 [R] COG0679 Predicted permeases Ype Yersinia pestis Length = 318 Score = 73.9 bits (180), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 82/271 (30%), Positives = 116/271 (42%), Gaps = 11/271 (4%) Query: 28 DEFWAGMEKLVYFLLFPALLFYSTARLKVDLSVTGGLVQTGLLALLAGIALTWLGKPFLR 87 D F G +LV+ L P LLF+S A V L L G L L + +L Sbjct: 34 DNFCDGATRLVFNLALPCLLFFSVATNHVSLLDNLPLAIYGAGGTLLTFLLLEVAAKWLV 93 Query: 88 STPMTYESGMQCAYRFNSYI-ALALATRMAGEEGAGLMAILLGFGVPLCNIAAVHALAPK 146 P +Q +R N+ I LA A G EG + ++ L V L N +V L Sbjct: 94 KDPRERGVFVQGGFRANTAIVGLAFAMTAYGAEGVAIGSMYLTVTVILFNTLSVITLTRS 153 Query: 147 ----------NSNLLRELAKNPLLVATAGGLTFSALGLHLPEVAGVVLSRLGAASIALGL 196 +LLR + NPL++ GL F+ L LP+V S + A ++ L L Sbjct: 154 LQAGQGGKISKLSLLRGIVTNPLIIGLVCGLLFAQTALSLPQVIVQTGSYISALALPLAL 213 Query: 197 LMVGAGLRLSGLKESKPVVGWFVFIKLFAVPAVAWLIGQHLQLPPLQLRIVVLFCSLPTA 256 L GA L + S V KLF VP + L G + L ++ LF + PTA Sbjct: 214 LCTGASLDWHAMFRSSNVAALSSVAKLFLVPILMTLGGLLMGFRGATLGVIFLFSATPTA 273 Query: 257 SSAYILAARMGGNGPFTAFLISFGTLLSALT 287 + +Y++ MGGN A +I+ T+ S T Sbjct: 274 AGSYVMTRAMGGNATLAANIIAITTVGSFFT 304