BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0026.p (205 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2546 [S] COG0344 Predicted membrane protein Rso Ralstonia sol... 274 1e-73 NMA1261 [S] COG0344 Predicted membrane protein NmA Neisseria men... 186 2e-47 NMB1062 [S] COG0344 Predicted membrane protein Nme Neisseria men... 179 4e-45 VC0523 [S] COG0344 Predicted membrane protein Vch Vibrio cholerae 166 4e-41 PM1696 [S] COG0344 Predicted membrane protein Pmu Pasteurella mu... 145 7e-35 HI0266 [S] COG0344 Predicted membrane protein Hin Haemophilus in... 143 2e-34 ygiH [S] COG0344 Predicted membrane protein Eco Escherichia coli... 140 2e-33 ZygiH [S] COG0344 Predicted membrane protein EcZ Escherichia col... 140 2e-33 ECs3942 [S] COG0344 Predicted membrane protein Ecs Escherichia c... 140 2e-33 YPO0647 [S] COG0344 Predicted membrane protein Ype Yersinia pestis 139 5e-33 >RSc2546 [S] COG0344 Predicted membrane protein Rso Ralstonia solanacearum Length = 207 Score = 274 bits (700), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 144/192 (75%), Positives = 158/192 (82%), Gaps = 1/192 (0%) Query: 11 YLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGDGFKGWLAVWL 70 YLIGS+SFAV+VS+ GL+DPRTYGS NPGATNVLRSGNKKAA LTLLGD KGWLAVWL Sbjct: 15 YLIGSVSFAVVVSRAMGLADPRTYGSGNPGATNVLRSGNKKAAILTLLGDAAKGWLAVWL 74 Query: 71 AQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLALDVWLGLATLA 130 AQ P YGV+D GIALV +A FLGHL+PVF RF GGKGVATA GILLAL WLGLATLA Sbjct: 75 AQLLAPRYGVEDMGIALVVIAAFLGHLYPVFHRFTGGKGVATAAGILLALSGWLGLATLA 134 Query: 131 TWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIYRHRKNIGNLL 190 TWL +A FRYSSLAALV+A+FAPFYY LLFG D + A+ M+ LLI RHR NI LL Sbjct: 135 TWLIIATFFRYSSLAALVSAVFAPFYYVLLFG-IDPLAGAIAVMSVLLIARHRANIAKLL 193 Query: 191 AGKESRIGDKKK 202 AGKESRIG+KKK Sbjct: 194 AGKESRIGEKKK 205 >NMA1261 [S] COG0344 Predicted membrane protein NmA Neisseria meningitidis Z2491 Length = 200 Score = 186 bits (473), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 115/201 (57%), Positives = 140/201 (69%), Gaps = 1/201 (0%) Query: 1 MYNILFAIGAYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGD 60 M+NI +YLIGSLSFAV+VSK +G+ DPRTYGS NPGATNVLRSG KKAAALTLLGD Sbjct: 1 MFNIPAVAVSYLIGSLSFAVIVSKYYGMDDPRTYGSGNPGATNVLRSGKKKAAALTLLGD 60 Query: 61 GFKGWLAVWLAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLAL 120 KG +AV LA+ G+ D+ IA V LA +GH+WPVFF F GGKGVATALG+LLAL Sbjct: 61 AAKGLVAVLLARVLQEPLGLSDSAIAAVALAALVGHMWPVFFGFKGGKGVATALGVLLAL 120 Query: 121 DVWLGLATLATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIY 180 L WL +AF F+ SSLAAL A + AP L F + A +A+A L++ Sbjct: 121 SPTTALVCALIWLVMAFGFKVSSLAALTATIAAPL-AALFFMPHTSWIFATLAIAILVLL 179 Query: 181 RHRKNIGNLLAGKESRIGDKK 201 RH+ NI NL+ GKES+IG+K+ Sbjct: 180 RHKSNILNLIKGKESKIGEKR 200 >NMB1062 [S] COG0344 Predicted membrane protein Nme Neisseria meningitidis MC58 Length = 200 Score = 179 bits (453), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 112/201 (55%), Positives = 136/201 (67%), Gaps = 1/201 (0%) Query: 1 MYNILFAIGAYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGD 60 M+NI +YLIGSLSFAV+VSK +G+ DPRTYGS NPGATNVLRSG KKAAALTLLGD Sbjct: 1 MFNIPAVAVSYLIGSLSFAVIVSKYYGMDDPRTYGSGNPGATNVLRSGKKKAAALTLLGD 60 Query: 61 GFKGWLAVWLAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLAL 120 KG +AV LA+ G+ D+ IA V LA +GH+WPVFF F GGKGVATALG+LLAL Sbjct: 61 AAKGLVAVLLARVLQEPLGLSDSAIAAVALAALVGHMWPVFFGFKGGKGVATALGVLLAL 120 Query: 121 DVWLGLATLATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIY 180 L WL +AF F+ SSLAAL A + AP + A VA+A L+++ Sbjct: 121 SPATALVCALIWLVMAFGFKVSSLAALTATIAAPVAASFFMPHVSWV-WATVAIALLVLF 179 Query: 181 RHRKNIGNLLAGKESRIGDKK 201 RH+ NI LL G+ES+IG + Sbjct: 180 RHKSNIVKLLEGRESKIGGSR 200 >VC0523 [S] COG0344 Predicted membrane protein Vch Vibrio cholerae Length = 208 Score = 166 bits (420), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 92/195 (47%), Positives = 119/195 (61%), Gaps = 7/195 (3%) Query: 8 IGAYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGDGFKGWLA 67 I AYL+GS+S AVL+ ++ L DPR GS+NPGATNVLR G KKAA LL D KG + Sbjct: 10 IFAYLLGSISSAVLICRVLRLPDPRNVGSQNPGATNVLRIGGKKAAVAVLLCDMLKGTIP 69 Query: 68 VWLAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLALDVWLGLA 127 VW G ++ + LV +A LGH++P+FF F GGKGVATALG + + + L Sbjct: 70 VW----GGYFLNIEPFMLGLVAIAACLGHMYPIFFHFKGGKGVATALGAIAPIGLDLTAM 125 Query: 128 TLATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIYRHRKNIG 187 +ATWL V FRYSSLAALV L AP Y L+ L V + L++ RH +N+ Sbjct: 126 VMATWLVVVVLFRYSSLAALVTVLLAPLYTWLI---KPQYTLPVAMLCCLIVLRHHQNVK 182 Query: 188 NLLAGKESRIGDKKK 202 L AG E ++G+K K Sbjct: 183 RLFAGTEPKVGEKNK 197 >PM1696 [S] COG0344 Predicted membrane protein Pmu Pasteurella multocida Length = 201 Score = 145 bits (365), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 87/205 (42%), Positives = 119/205 (58%), Gaps = 7/205 (3%) Query: 1 MYNILFAIGAYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGD 60 ++ I + AYL+GS+S A+L+ +L GL DPR GS NPGATNVLR G + A LL D Sbjct: 3 LFAIFYLFLAYLLGSVSSAILLCRLAGLPDPRESGSHNPGATNVLRIGGRWVALSVLLFD 62 Query: 61 GFKGWLAVWLAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLAL 120 KG L VWL G + G+ + +V L LGH++P+FF+F GGKGVATA G + + Sbjct: 63 MLKGMLPVWL----GYYLGLTHFELGMVALGACLGHIFPIFFKFKGGKGVATAFGAIAPI 118 Query: 121 DVWLGLATLATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIY 180 + + L TWL + F YSSL+A++ AL PFY ++ V + LLIY Sbjct: 119 SWGVAGSMLGTWLLIFFVSGYSSLSAVMTALLVPFY---VWWFKPEFTFPVALVCCLLIY 175 Query: 181 RHRKNIGNLLAGKESRIGDKKKAGK 205 RH NI L G+E ++ +K K K Sbjct: 176 RHHDNIQRLWRGQEDKVWNKLKNKK 200 >HI0266 [S] COG0344 Predicted membrane protein Hin Haemophilus influenzae Length = 199 Score = 143 bits (361), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 81/202 (40%), Positives = 119/202 (58%), Gaps = 7/202 (3%) Query: 1 MYNILFAIGAYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGD 60 ++ + + + AYL+GS+S A+L+ ++ GL DPR GS NPGATNVLR GN+K+A L+ D Sbjct: 3 LFALFYMLFAYLLGSISSAILICRIAGLPDPRQNGSHNPGATNVLRIGNRKSALAVLIFD 62 Query: 61 GFKGWLAVWLAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLAL 120 KG + VW G + G+ + +V L LGH++P+FF+F GGKGVATA G + + Sbjct: 63 MLKGMIPVWA----GYYLGLTQFELGMVALGACLGHIFPIFFQFKGGKGVATAFGAIAPI 118 Query: 121 DVWLGLATLATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIY 180 + + TW+ V YSSL+A+++AL PFY ++ V + LLIY Sbjct: 119 SWAVAGSMFGTWIFVFLVSGYSSLSAVISALLVPFY---VWWFKPEFTFPVALVCCLLIY 175 Query: 181 RHRKNIGNLLAGKESRIGDKKK 202 RH NI L G+E ++ K K Sbjct: 176 RHHDNIQRLWRGQEDKVWAKFK 197 >ygiH [S] COG0344 Predicted membrane protein Eco Escherichia coli K12 Length = 205 Score = 140 bits (352), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 88/193 (45%), Positives = 110/193 (56%), Gaps = 7/193 (3%) Query: 10 AYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGDGFKGWLAVW 69 AYL GS+S A+LV +L GL DPRT GS NPGATNVLR G K AA L+ D KG L VW Sbjct: 12 AYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVW 71 Query: 70 LAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLALDVWLGLATL 129 A + GV + L+ +A LGH+WPVFF F GGKGVATA G + + L Sbjct: 72 GAYEL----GVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMA 127 Query: 130 ATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIYRHRKNIGNL 189 TWL YSSL A+V+AL APFY ++ V ++ L++ RH NI L Sbjct: 128 GTWLLTVLLSGYSSLGAIVSALIAPFY---VWWFKPQFTFPVSMLSCLILLRHHDNIQRL 184 Query: 190 LAGKESRIGDKKK 202 +E++I K K Sbjct: 185 WRRQETKIWTKFK 197 >ZygiH [S] COG0344 Predicted membrane protein EcZ Escherichia coli O157:H7 EDL933 Length = 205 Score = 140 bits (352), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 88/193 (45%), Positives = 110/193 (56%), Gaps = 7/193 (3%) Query: 10 AYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGDGFKGWLAVW 69 AYL GS+S A+LV +L GL DPRT GS NPGATNVLR G K AA L+ D KG L VW Sbjct: 12 AYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVW 71 Query: 70 LAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLALDVWLGLATL 129 A + GV + L+ +A LGH+WPVFF F GGKGVATA G + + L Sbjct: 72 GAYEL----GVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMA 127 Query: 130 ATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIYRHRKNIGNL 189 TWL YSSL A+V+AL APFY ++ V ++ L++ RH NI L Sbjct: 128 GTWLLTVLLSGYSSLGAIVSALIAPFY---VWWFKPQFTFPVSMLSCLILLRHHDNIQRL 184 Query: 190 LAGKESRIGDKKK 202 +E++I K K Sbjct: 185 WRRQETKIWTKFK 197 >ECs3942 [S] COG0344 Predicted membrane protein Ecs Escherichia coli O157:H7 Length = 205 Score = 140 bits (352), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 88/193 (45%), Positives = 110/193 (56%), Gaps = 7/193 (3%) Query: 10 AYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGDGFKGWLAVW 69 AYL GS+S A+LV +L GL DPRT GS NPGATNVLR G K AA L+ D KG L VW Sbjct: 12 AYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVW 71 Query: 70 LAQKFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLALDVWLGLATL 129 A + GV + L+ +A LGH+WPVFF F GGKGVATA G + + L Sbjct: 72 GAYEL----GVSPFWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMA 127 Query: 130 ATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIYRHRKNIGNL 189 TWL YSSL A+V+AL APFY ++ V ++ L++ RH NI L Sbjct: 128 GTWLLTVLLSGYSSLGAIVSALIAPFY---VWWFKPQFTFPVSMLSCLILLRHHDNIQRL 184 Query: 190 LAGKESRIGDKKK 202 +E++I K K Sbjct: 185 WRRQETKIWTKFK 197 >YPO0647 [S] COG0344 Predicted membrane protein Ype Yersinia pestis Length = 216 Score = 139 bits (349), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 89/200 (44%), Positives = 112/200 (56%), Gaps = 11/200 (5%) Query: 8 IGAYLIGSLSFAVLVSKLFGLSDPRTYGSKNPGATNVLRSGNKKAAALTLLGDGFKGWLA 67 I AYL GS+S A+LV ++ L DPRT+GS NPGATNVLR G + AA LL D KG L Sbjct: 10 IFAYLCGSISSAILVCRVARLPDPRTHGSGNPGATNVLRIGGRTAAVAVLLFDILKGMLP 69 Query: 68 VWLAQ--KFGPHYGVDDTGIALVTLAVFLGHLWPVFFRFVGGKGVATALGILLALDVWLG 125 VW+A P Y + L +A LGH++PVFF F GGKGVATA G + + L Sbjct: 70 VWIAYLLHIPPLY------LGLTAIAACLGHIYPVFFHFKGGKGVATAFGAIAPIGWDLT 123 Query: 126 LATLATWLAVAFAFRYSSLAALVAALFAPFYYGLLFGTTDGILLAVVAMAALLIYRHRKN 185 TWL YSSL A+V+AL APFY ++ V ++ L++ RH N Sbjct: 124 GLMTGTWLLTVLLSGYSSLGAIVSALIAPFY---VWWFKPQFTFPVAMLSCLILMRHHDN 180 Query: 186 IGNLLAGKESRIGDKKKAGK 205 I L GKE +I DK + K Sbjct: 181 IQRLWRGKEGKIWDKLRKKK 200