BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0024.p (341 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0378 [E] COG0547 Anthranilate phosphoribosyltransferase Rso R... 285 1e-76 ybiB [E] COG0547 Anthranilate phosphoribosyltransferase Eco Esch... 256 6e-68 ZybiB [E] COG0547 Anthranilate phosphoribosyltransferase EcZ Esc... 256 6e-68 ECs0878 [E] COG0547 Anthranilate phosphoribosyltransferase Ecs E... 256 6e-68 STM0822 [E] COG0547 Anthranilate phosphoribosyltransferase Sty S... 244 2e-64 YPO2522 [E] COG0547 Anthranilate phosphoribosyltransferase Ype Y... 243 6e-64 PA2609 [E] COG0547 Anthranilate phosphoribosyltransferase Pae Ps... 125 1e-28 aq_209 [E] COG0547 Anthranilate phosphoribosyltransferase Aae Aq... 81 3e-15 all0601 [E] COG0547 Anthranilate phosphoribosyltransferase Nos N... 80 7e-15 sll1634 [E] COG0547 Anthranilate phosphoribosyltransferase Syn S... 76 9e-14 >RSc0378 [E] COG0547 Anthranilate phosphoribosyltransferase Rso Ralstonia solanacearum Length = 339 Score = 285 bits (728), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 160/315 (50%), Positives = 209/315 (66%), Gaps = 13/315 (4%) Query: 31 FVAAPFIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIA 90 F AA FIKEIGRG DGAR+L + DAR ++ AML+GRV+D++LGAIL+A RIKGE+ +E+ Sbjct: 23 FPAARFIKEIGRGADGARALVKHDARALFAAMLEGRVADVQLGAILMAYRIKGETPEELD 82 Query: 91 GFLDAAEAS---MPALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGV 147 G L+A A +PA AP G PVV+PSYNG+R+ NL PLL LL R GVPVL+HG+ Sbjct: 83 GMLEATHARCLPLPAPDAPGGTL-PVVIPSYNGARRQPNLVPLLAALLAREGVPVLVHGI 141 Query: 148 THDPQRVTSAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGV 207 R+T+A +F ALG P +++A+A + + + AFVPI VL+P + LL R I+G+ Sbjct: 142 RRFDGRITTATLFDALGWPVCEHMDEARARLESDRLAFVPIDVLSPDLKALLDKREIVGL 201 Query: 208 RNSTHTVVKIMQPFAG----PALRLTSYTHPEYLEMLTDYFSNAAPPERGDAFLMRGTEG 263 RNS+HTVVK++QP G ALRL SYTHPEY + LTDYF + L RGTEG Sbjct: 202 RNSSHTVVKMLQPIGGHAPHEALRLVSYTHPEYRDTLTDYFLR----HPANVLLARGTEG 257 Query: 264 ETVANARRAQRIDWFSGGTRTVLVE-KQSVAEELPDLPEGQDAAATAAWIREVLEGQRPV 322 E VA+ARR ++W G ++E + + + P+LP G DA ATA WI VL G++PV Sbjct: 258 EAVADARRGSAVEWLHDGLHETVIEAAEGSSSQPPELPAGTDAEATARWIEAVLGGRQPV 317 Query: 323 PEAIAEQVEHCVDVA 337 PE IA QV V A Sbjct: 318 PEPIARQVRAIVRCA 332 >ybiB [E] COG0547 Anthranilate phosphoribosyltransferase Eco Escherichia coli K12 Length = 320 Score = 256 bits (654), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 140/301 (46%), Positives = 183/301 (60%), Gaps = 8/301 (2%) Query: 36 FIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDA 95 IKEIGRGK+ AR L R AR +Y ML+G V DLELG +L+A+RIKGE E+ GF +A Sbjct: 6 IIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGGVLIALRIKGEGEAEMLGFYEA 65 Query: 96 AEASMPALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQRVT 155 + L PAG P+V+PSYNG+RK ANLTPLL +LL + G PV++HGV+ DP RV Sbjct: 66 MQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLAILLHKLGFPVVVHGVSEDPTRVL 125 Query: 156 SAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNSTHTVV 215 + IF +G QAQA + QP F+P+ P + + L MR +GVRNS HT+ Sbjct: 126 TETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGAFCPPLEKQLAMRWRMGVRNSAHTLA 185 Query: 216 KIMQPFA-GPALRLTSYTHPEYLEMLTDYFSNAAPPERGDAFLMRGTEGETVANARRAQR 274 K+ PFA G ALRL+S +HPEY+ + +FS+ G A LM GTEGE AN +R + Sbjct: 186 KLATPFAEGEALRLSSVSHPEYIGRVAKFFSDIG----GRALLMHGTEGEVYANPQRCPQ 241 Query: 275 IDWFSGGTRTVLVEKQSVA-EELPDLPEGQDAAATAAWIREVLEGQRPVPEAIAEQVEHC 333 I+ VL EKQ A EL LP+ +D TA WI L G P+PE++ Q+ C Sbjct: 242 INLIDREGMRVLYEKQDTAGSEL--LPQAKDPETTAQWIERCLAGSEPIPESLKIQMACC 299 Query: 334 V 334 + Sbjct: 300 L 300 >ZybiB [E] COG0547 Anthranilate phosphoribosyltransferase EcZ Escherichia coli O157:H7 EDL933 Length = 320 Score = 256 bits (653), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 140/301 (46%), Positives = 185/301 (61%), Gaps = 8/301 (2%) Query: 36 FIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDA 95 IKEIGRGK+ AR L R AR +Y ML+G V DLELG +L+A+RIKGE E+ GF +A Sbjct: 6 IIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGGVLIALRIKGEGEAEMLGFYEA 65 Query: 96 AEASMPALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQRVT 155 + L PAG P+V+PSYNG+RK ANLTPLL +LL + G PV++HGV+ DP RV Sbjct: 66 MQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLAILLHKLGFPVVVHGVSEDPTRVL 125 Query: 156 SAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNSTHTVV 215 + IF +G QAQA + QP F+P+ P + + L MR +GVRNS HT+ Sbjct: 126 TETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGAFCPPLEKQLAMRWRMGVRNSAHTLA 185 Query: 216 KIMQPFA-GPALRLTSYTHPEYLEMLTDYFSNAAPPERGDAFLMRGTEGETVANARRAQR 274 K+ PFA G ALRL+S +HPEY+ + +FS+ G A LM GTEGE AN +R + Sbjct: 186 KLATPFAEGEALRLSSVSHPEYIGRVAKFFSDIG----GRALLMHGTEGEVYANPQRCPQ 241 Query: 275 IDWFSGGTRTVLVEKQSVA-EELPDLPEGQDAAATAAWIREVLEGQRPVPEAIAEQVEHC 333 I+ VL EKQ A EL LP+ +D TA WI+ L G+ P+PE++ Q+ C Sbjct: 242 INLIDREEMRVLYEKQDPAGSEL--LPQAKDPETTAQWIQRCLAGREPIPESLKIQMACC 299 Query: 334 V 334 + Sbjct: 300 L 300 >ECs0878 [E] COG0547 Anthranilate phosphoribosyltransferase Ecs Escherichia coli O157:H7 Length = 320 Score = 256 bits (653), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 140/301 (46%), Positives = 185/301 (61%), Gaps = 8/301 (2%) Query: 36 FIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDA 95 IKEIGRGK+ AR L R AR +Y ML+G V DLELG +L+A+RIKGE E+ GF +A Sbjct: 6 IIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGGVLIALRIKGEGEAEMLGFYEA 65 Query: 96 AEASMPALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQRVT 155 + L PAG P+V+PSYNG+RK ANLTPLL +LL + G PV++HGV+ DP RV Sbjct: 66 MQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLAILLHKLGFPVVVHGVSEDPTRVL 125 Query: 156 SAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNSTHTVV 215 + IF +G QAQA + QP F+P+ P + + L MR +GVRNS HT+ Sbjct: 126 TETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGAFCPPLEKQLAMRWRMGVRNSAHTLA 185 Query: 216 KIMQPFA-GPALRLTSYTHPEYLEMLTDYFSNAAPPERGDAFLMRGTEGETVANARRAQR 274 K+ PFA G ALRL+S +HPEY+ + +FS+ G A LM GTEGE AN +R + Sbjct: 186 KLATPFAEGEALRLSSVSHPEYIGRVAKFFSDIG----GRALLMHGTEGEVYANPQRCPQ 241 Query: 275 IDWFSGGTRTVLVEKQSVA-EELPDLPEGQDAAATAAWIREVLEGQRPVPEAIAEQVEHC 333 I+ VL EKQ A EL LP+ +D TA WI+ L G+ P+PE++ Q+ C Sbjct: 242 INLIDREEMRVLYEKQDPAGSEL--LPQAKDPETTAQWIQRCLAGREPIPESLKIQMACC 299 Query: 334 V 334 + Sbjct: 300 L 300 >STM0822 [E] COG0547 Anthranilate phosphoribosyltransferase Sty Salmonella typhimurium LT2 Length = 324 Score = 244 bits (624), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 136/301 (45%), Positives = 180/301 (59%), Gaps = 6/301 (1%) Query: 36 FIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDA 95 IKEIGRGK+ AR L AR +Y ML+G V DLE+G+IL+A+RIKGE E+ GF +A Sbjct: 6 IIKEIGRGKNHARDLDLDTARGLYTRMLNGDVPDLEMGSILMALRIKGEGEAEMLGFYEA 65 Query: 96 AEASMPALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQRVT 155 + L PA PVV+PSYNG+RK ANLTPLL +LL + G PV++HGV+ DP RV Sbjct: 66 MQNHTIKLTPPADRPLPVVIPSYNGARKQANLTPLLAILLHKLGFPVVVHGVSEDPTRVL 125 Query: 156 SAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNSTHTVV 215 + IF +G QAQA + QP F+P++ L P + + L MR +GVRNS H++ Sbjct: 126 TETIFELMGIIPTLHGGQAQAKLDGRQPVFIPVSALCPPLEKQLAMRWRMGVRNSAHSLA 185 Query: 216 KIMQPFA-GPALRLTSYTHPEYLEMLTDYFSNAAPPERGDAFLMRGTEGETVANARRAQR 274 K+ PFA ALRL+S +HPEY+ + +FS G A LM GTEGE AN +R + Sbjct: 186 KLATPFAEDAALRLSSVSHPEYVPRVATFFSRIG----GRALLMHGTEGEVYANPQRCPQ 241 Query: 275 IDWFSGGTRTVLVEKQSVAEELP-DLPEGQDAAATAAWIREVLEGQRPVPEAIAEQVEHC 333 I VL E+QS + P LP +D TA WI L G PVP+++ Q+ C Sbjct: 242 ISLIDSRGVQVLHERQSDTYDEPLSLPATKDPEITARWIERCLAGHEPVPQSLKTQMACC 301 Query: 334 V 334 + Sbjct: 302 L 302 >YPO2522 [E] COG0547 Anthranilate phosphoribosyltransferase Ype Yersinia pestis Length = 319 Score = 243 bits (619), Expect = 6e-64, Method: Compositional matrix adjust. Identities = 139/305 (45%), Positives = 198/305 (64%), Gaps = 6/305 (1%) Query: 36 FIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDA 95 IKE+GRGK+ AR L + A +Y+AML G+V LELG IL+A RIKGES QEI GF A Sbjct: 6 IIKEVGRGKNHARDLDQPTAYALYKAMLAGQVPALELGGILIAFRIKGESEQEILGFYQA 65 Query: 96 AEASMPALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQRVT 155 + + +LRAP PVV+PSYNG+RK ANLTPLL +LL R G+PV++HGVT D RVT Sbjct: 66 MQEQVMSLRAPVDRPLPVVIPSYNGARKQANLTPLLALLLSRLGLPVVVHGVTEDSSRVT 125 Query: 156 SAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNSTHTVV 215 SAEIF L P + S+++AQ + G P F+P++ L+ + + L R +GVRNS+HT+ Sbjct: 126 SAEIFQQLNIPWSLSVQEAQQRLDNGLPVFIPVSALSMQLDQQLQQRWRMGVRNSSHTLA 185 Query: 216 KIMQPFA-GPALRLTSYTHPEYLEMLTDYFSNAAPPERGDAFLMRGTEGETVANARRAQR 274 K+ PF ALR+ S +HPEY++ + +F + P L++GTEGE AN R Sbjct: 186 KLATPFTHDKALRVASVSHPEYMQKVGGFFQAISAP----GLLLQGTEGEVYANPLRCPP 241 Query: 275 IDWFSGGTRTVLVEKQSVAEELPDLPEGQDAAATAAWIREVLEGQRPVPEAIAEQVEHCV 334 I + + G +T+L+++ S +P+LP +DA TA WI L G++P+P++I +Q+ C+ Sbjct: 242 IHYINDGEQTILLDRSS-ESVVPELPLSKDAVITARWIEGCLAGEQPIPDSILKQLACCL 300 Query: 335 DVAAR 339 A + Sbjct: 301 VAAGQ 305 >PA2609 [E] COG0547 Anthranilate phosphoribosyltransferase Pae Pseudomonas aeruginosa Length = 327 Score = 125 bits (314), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 84/248 (33%), Positives = 127/248 (51%), Gaps = 16/248 (6%) Query: 25 LSSHAAFVAAPFIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGE 84 LS+ A A F++ +G+GK GARSL+R++AR +LDGRV D +LGA L+ +R K E Sbjct: 3 LSTPAEHPFAQFVRILGKGKRGARSLTREEAREALGMILDGRVEDTQLGAFLMLLRHKEE 62 Query: 85 SVQEIAGFLDAAEASM--PALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPV 142 S +E+AGF +A + P+LR + PSY G ++ L L GV + Sbjct: 63 SSEELAGFTEAVRERLQVPSLR------VDLDWPSYAGKKRHLPWYLLAAKCLAGHGVRI 116 Query: 143 LMH-GVTHDPQRVTSAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGM 201 LMH G H R+ S ++ AL P Q + + G AF+P+ P + R++ + Sbjct: 117 LMHGGGAHTAGRLYSEQLLAALEIPLCHDWLQVEQALERGHLAFIPLGAWMPVLQRMIDL 176 Query: 202 RRILGVRNSTHTVVKIMQPFAGPALRLTSYTHPEYLEMLTDYFSNAAPPERGD-AFLMRG 260 R LG+R+ H++V+++ P + L S HP Y E A GD A +++G Sbjct: 177 RNTLGLRSPIHSLVRLLNPLNADCI-LQSIFHPGYQET-----HREASRLLGDRAIVIKG 230 Query: 261 TEGETVAN 268 GE N Sbjct: 231 EGGEIEVN 238 >aq_209 [E] COG0547 Anthranilate phosphoribosyltransferase Aae Aquifex aeolicus Length = 309 Score = 81.3 bits (199), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 64/219 (29%), Positives = 103/219 (47%), Gaps = 30/219 (13%) Query: 37 IKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDAA 96 K++ R KD + LS+++A +++A+L+G++SD++ A L AMRIKGE+ +E+ G + A Sbjct: 8 FKKLTRLKDNLQDLSQEEAYEVFRAILEGKLSDIKTTAFLTAMRIKGETSEELLGVIKAI 67 Query: 97 EASM--PALRAPAGPYAPVVLPSYNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQR- 153 + M P + A +Y+G + + P L R GV H P + Sbjct: 68 KERMNFPQKKEDALDLG----LNYDGKNRTIYILPSALWLCSRLGVEFTNHYALGAPTKE 123 Query: 154 -VTSAEIFTALGQPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNSTH 212 VT E+ LG S FV AP + +L+ +RR LG R+ + Sbjct: 124 GVTLYEVVKELGVDMNVS--------------FVDQKNYAPELYKLMPLRRELGFRSLIN 169 Query: 213 TVVKIMQPFAGPALRLTSYTHP------EYLEML--TDY 243 TV K + PF + ++ + P E LE+L DY Sbjct: 170 TVEKFLNPFQTKKIVVSIFHKPYFDKNAELLELLGIEDY 208 >all0601 [E] COG0547 Anthranilate phosphoribosyltransferase Nos Nostoc sp. PCC 7120 Length = 356 Score = 80.1 bits (196), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 63/210 (30%), Positives = 100/210 (47%), Gaps = 6/210 (2%) Query: 30 AFVAAPFIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEI 89 + V +K++G G SL+R +A T + M G + ++GA L+A RIK + +E+ Sbjct: 2 SIVFRDLLKKVGSGNHTGESLNRVEAATATKMMFLGEATPAQIGAFLIAHRIKRPTGEEL 61 Query: 90 AGFLDAAEASMPALRAPAGPYAPVVLPS--YNGSRKMANLTPLLCMLLVRRGVPVLMHGV 147 AG LDA + P L+ P PV++ Y+G + A ++P+ +L+ PV++HG Sbjct: 62 AGMLDAFDELGPKLQ-PISSKRPVIVFGIPYDGRTRTAPISPVTALLMATVEQPVVIHGG 120 Query: 148 THDPQR--VTSAEIFTALGQPHAA-SIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRI 204 P + + EI+ LG S+E+ Q + A FV P + R Sbjct: 121 DRLPTKYGLPLTEIWQGLGVNWTTLSLEKTQEVFAQTGIGFVYTPKHFPLTNSIWEYRDQ 180 Query: 205 LGVRNSTHTVVKIMQPFAGPALRLTSYTHP 234 LG R T+ I P+AG A + Y HP Sbjct: 181 LGKRPPLATMELIWCPYAGDAHVIAGYVHP 210 >sll1634 [E] COG0547 Anthranilate phosphoribosyltransferase Syn Synechocystis Length = 349 Score = 76.3 bits (186), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 4/214 (1%) Query: 36 FIKEIGRGKDGARSLSRQDARTMYQAMLDGRVSDLELGAILLAMRIKGESVQEIAGFLDA 95 ++++G G +++L+R+++ + ML + ++GA L+A RIK + E+AG LDA Sbjct: 8 LLRKVGSGPHTSKNLTREESAQAMKLMLTQEATPAQIGAFLIAHRIKRPTGTELAGMLDA 67 Query: 96 AEASMPALRAPAGPYAPVVLPS-YNGSRKMANLTPLLCMLLVRRGVPVLMHGVTHDPQR- 153 E P + A + +VL Y+G + + PL ++L G PV+ HG P + Sbjct: 68 FEQWGPKIPALSSGQTVIVLSQPYDGRDRTCPVGPLTALVLATAGCPVIQHGGDRMPTKE 127 Query: 154 -VTSAEIFTALG-QPHAASIEQAQALMAAGQPAFVPITVLAPAIARLLGMRRILGVRNST 211 + E++ LG + S+ Q ++ FV + P +L+ R +G R Sbjct: 128 GIPLVELWEGLGVNWRSPSLLATQDILEKTNVGFVYLPKYFPEAQKLVIYREEIGKRPPL 187 Query: 212 HTVVKIMQPFAGPALRLTSYTHPEYLEMLTDYFS 245 T+ I P+AG + + HP M+ + S Sbjct: 188 ATLELIWVPYAGKHHVVAGFVHPPTENMIAEALS 221