BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0004.0016.p (1158 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1190 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta ... 859 0.0 BMEI2023 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta... 231 5e-60 SMc02760 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta... 218 8e-56 AGc39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta su... 167 1e-40 BS_addA [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta ... 163 3e-39 BH2980 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta s... 162 7e-39 mll5083 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta ... 157 2e-37 SA0828 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta s... 155 4e-37 RC1114 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta s... 145 5e-34 lin2368 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta ... 142 6e-33 >RSc1190 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Rso Ralstonia solanacearum Length = 1177 Score = 859 bits (2219), Expect = 0.0, Method: Compositional matrix adjust. Identities = 543/1196 (45%), Positives = 722/1196 (60%), Gaps = 91/1196 (7%) Query: 10 AYEVNGEAVDAAVFTRAACDPRHSVVVEACAGSGKTWLLVARMLRLLLAGAQAPELLAIT 69 AYE +G V F+RAACDP SVVVEACAGSGKTWLLV RMLRLLLAGA ++LAIT Sbjct: 5 AYERDGAPVSPEAFSRAACDPLRSVVVEACAGSGKTWLLVTRMLRLLLAGAAPSDILAIT 64 Query: 70 FTRKAAQEMRERLLELLHELALADEAGAAALLRERGVAEPDLPRLLPLARGLYERILSSE 129 FTRKAA+EMR+RLL+ L +LA AD+A L R V E + P L+ +ARGLY R+L S Sbjct: 65 FTRKAAEEMRQRLLDSLAQLAGADDAAVVRELVARTVDEREAPGLVAVARGLYGRVLESP 124 Query: 130 QSLSIDTFHSWFARLLQIAPLASGVPHGYTLTEKNGELLDEAYRRFMQTLREPEGAHIKA 189 ++IDTFH WF LL+ APL+SGVP G +L E G L EA+ F + L E A ++A Sbjct: 125 SRMAIDTFHGWFGGLLRGAPLSSGVPQGASLREDAGRLRREAWAPFWRRLLAEEHAELRA 184 Query: 190 ALLELYELAGDFNARQLLDAFIDKRAEWWAATQDDDQEDEEGAEEHAAPAPLRWLQALCG 249 A L +L GDF A +LLDA +R++WWA + A PL L L G Sbjct: 185 AYDTLVDLVGDFQAGRLLDAMFAQRSDWWAY------------KAQAGAHPLGPLDDLLG 232 Query: 250 ADAQRDARLSLWEEHALVARPSQLAILLGQGGSANQARAVAIESALSAGPALE------- 302 DA D + ++ AL+A +++ LGQGG+A RAV IE+A++A AL+ Sbjct: 233 DDAHTDPLIEALQDAALLADMLRVSGWLGQGGAAEGKRAVQIETAVTAARALDLSDAAAR 292 Query: 303 --HFDALYSQFFDDKDKPRKNGKVKSLLAALVQHFEASEDAALAAFEAEFNAV-GEALRK 359 F+AL++ F KPR K+L+ A+ EDAA A+ +AV EAL Sbjct: 293 RHAFEALFTAFHTQAGKPRACKPTKALVKAI------GEDAAQTL--ADLHAVLCEALAV 344 Query: 360 LQGRSKEKDVLQLNAALFTAGRAYLACYQEVKAEQRVLDFADLEWQAYRLLRNEASAAYL 419 Q R E V +NAALFT G A + YQ K + R +DF DLEW+A RL+R+E +AAYL Sbjct: 345 YQARRHESRVRAINAALFTLGDALIERYQAYKRQARAMDFTDLEWEAARLMRDEDTAAYL 404 Query: 420 QTRLDARYKHILLDEFQDTNPLQWCIVRCWLDAYGGDAAQPSVFVVGDPKQSIYRFRRAE 479 Q RLDARYKH+LLDEFQDTNP+QW I++ WL Y G +P+VF+VGDPKQSIYRFRRA+ Sbjct: 405 QVRLDARYKHLLLDEFQDTNPMQWRILQGWLRGYEGTGTRPTVFLVGDPKQSIYRFRRAD 464 Query: 480 PRVFVAAREMLRAQ-GAAILRANQTRRNATAVVDVLNRSFVM----GGNPLFSQQTT-LG 533 R+F AAR+ML A A +LR N+TRRNA AV++ +N F++ G P++++Q+T + Sbjct: 465 ARLFEAARDMLVAAFDATVLRTNRTRRNAPAVLEWVNAVFLLARARGDYPIYAEQSTAVD 524 Query: 534 LAGGEVWRLPLARPDDGAENVSSADPDAASAAPEGEQEVIPWRNPLTTPRGEEDDARRLL 593 G LPL P+AA A E P R+ LT PR E D++R Sbjct: 525 APVGRALLLPLV-----------PVPEAAQA-----DETAP-RDSLTEPREEAGDSQRYD 567 Query: 594 EGQALAQALLKAYREVPVVEGKGARSMRWGDIMLLVRKRTHLAAYESALRAAGIPFISDK 653 EG+ +A L + V E R +RW D LLVR++ +LA YE ALR AG+P++S + Sbjct: 568 EGRQVAACLRALHAGERVRENGAERPVRWSDFQLLVRRKRYLADYERALRDAGVPYLSPR 627 Query: 654 RGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGGHW 713 RGGLL +LE DL ALL FL+TP LAHVL+SPI + TDDDL+ +A+ A W Sbjct: 628 RGGLLATLEALDLCALLDFLMTPQADLPLAHVLRSPIFAVTDDDLIALAQAGEGASAPTW 687 Query: 714 WQQLQAMQQEGAASAALVRAVTLLQRWLLAAPHLPVHDLLDMILHQGELVAHYAQHASPL 773 W++L A+ A+A RA LL RWL AP LPVHDLLD I++ GEL YA+ Sbjct: 688 WERLAALADRPHAAAQWRRAHRLLSRWLAVAPTLPVHDLLDHIVYTGELKRRYAERVPEA 747 Query: 774 TRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPDEA----------S 823 R Q L N+ AF++L+L++D GRYPSLPKF+ LR +++ ++PDE + Sbjct: 748 NREQALANLDAFLKLALDLDGGRYPSLPKFMAELRAIRQGDEEESPDEGVQGDAAEAPDA 807 Query: 824 VDA-----SADAVRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDEDAPTHF 878 +DA DAV+ILTVH++KGLEAP V +LD++HSD+ D +GIL WP +AP HF Sbjct: 808 IDAELASEGLDAVQILTVHASKGLEAPFVVLLDSHHSDTRADTVGILIDWPPGAEAPAHF 867 Query: 879 SAFGRRSERGSARDPLFEEEETLRTQEDWNLLYVAVTRAKQLLLVSGVAGTR-GAGAGGV 937 SAFG+ +ERG ARDPLF +E TL +E+WNLLYVA+TRA+Q L+VSGVA R GA A V Sbjct: 868 SAFGKAAERGRARDPLFAQEATLAERENWNLLYVAMTRARQALIVSGVANKRDGAAAQAV 927 Query: 938 VQG---------SWYQRLFASDAPVREISEEAVHGAEAADIEERFSLALFDPR-PLPMSL 987 +G SWY L + A E A A + ++A D R PL +++ Sbjct: 928 DEGDVPDVDGSASWYTLLATAGAATPAPVEAAAGAGGADHAASQ-AVAYHDFRVPLTVTV 986 Query: 988 -FGAPADDPQDAVPALTADGALVSTDAIDEGVALHALLERLTHGHAWPLHVPSASVLVRW 1046 G + DA TAD A+ A+ +G LHA+LERLT H P VP A+ + RW Sbjct: 987 RIGGAVERVADAPD--TAD-AIFDQGAVAQGELLHAVLERLTR-HGKPEQVPDAAAIARW 1042 Query: 1047 LGIS----AEMAQVVHAQAREVLAQPQLERFFNPALHRWARNEMEIVTPNG-LMRLDRVV 1101 G + A+ A+ A R +LA L F+PA A NE+E+ +P+G L+R+DR++ Sbjct: 1043 FGATGITDADAARATEA-VRRMLAAEALAHVFDPARFDVAHNEVELFSPDGALLRIDRLI 1101 Query: 1102 MFDDELWVIDYKRRLLDSERADYAAQLGRYRSALMSVFSDKQIRSALITAEGALIE 1157 DE+ V+DYK RLL ERA YA QL Y +A+ ++ + +R+ + TA+G I+ Sbjct: 1102 ERGDEVLVVDYKLRLLPVERAAYADQLRGYAAAVAPIYPGRAVRAGVATAQGEWID 1157 >BMEI2023 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Bme Brucella melitensis Length = 1180 Score = 231 bits (590), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 324/1206 (26%), Positives = 494/1206 (40%), Gaps = 154/1206 (12%) Query: 27 ACDPRHSVVVEACAGSGKTWLLVARMLRLLLAGAQAPELLAITFTRKAAQEMRERLLELL 86 A DP SV V A AGSGKT +L R++RLLL G ++L +T+T+ AA M+ R+ L Sbjct: 18 AADPSASVWVSANAGSGKTHVLTERVIRLLLEGTDPSKILCLTYTKAAAAVMQNRVFMRL 77 Query: 87 HELALADEAGAAALLRERGVAEPDLPRLLPLARGLYERILSSEQSLSIDTFHSWFARLLQ 146 E A+ + A L + P R+ AR L+ R L + + I T H++ +L Sbjct: 78 SEWAVLPDEALAERLEKLERRRPGAARVAS-ARRLFARALKTPGGMKIQTIHAFCEAILH 136 Query: 147 IAPLASGVPHGYTLTEK--NGELLDEAYRRFMQTLREPEGAHIKAALLELYELAGDFNAR 204 PL + + + + + L+ EA R ++T + AA ++ + AG+ + Sbjct: 137 QFPLEANIAGHFEMMDDLMQAALVGEARRTLLETAYGGGDPALAAAFADVLQAAGETGLQ 196 Query: 205 QLLDAFIDKRA--EWWAATQDDDQEDEEGAEEHAAPAPLRWLQALCGADAQRDARLS-LW 261 LLD + +R + + A E G H A R DA+ D L+ LW Sbjct: 197 SLLDEAVGRRNGLQLYLA--------ELGVGTHRVEALHRAFG--FEPDAREDDLLADLW 246 Query: 262 EEHALVARPSQLAILLGQGGSANQARAVAIESALSAGPALEHFDALYSQFFDDKDKPRKN 321 L + + +G S Q A+ ++ A + L + F +P+ Sbjct: 247 PVPEFSDDALDLILSIPKGASRAQDFALQLKRLEKASGLPDKIAVLRAAFLKSTGEPKSG 306 Query: 322 GKVKSLLAALVQHFEASEDAALAAFEAEFNAVGEALRKLQGRSKEKDVLQLNAALFTAGR 381 V S A+ L FE EF+ + R KE +++LN A T Sbjct: 307 SYVCS----------AAVKKLLPEFEEEFDTAAARVEMGLDRLKELRLVRLNLAALTLID 356 Query: 382 AYLACYQEVKAEQRVLDFADLEWQAYRLLRNEASAAYLQTRLDARYKHILLDEFQDTNPL 441 L Y ++K + +LDF DL + LL + ++Q +LD HIL+DE QDT+P Sbjct: 357 NLLQRYHDLKRRRGLLDFEDLITRTVALLARNGAGQWVQYKLDRGIDHILVDEAQDTSPD 416 Query: 442 QWCIVRC----WLDAYGGDAAQPSVFVVGDPKQSIYRFRRAEPRVFVAAREMLRAQGAAI 497 QW ++R + G Q ++F VGD KQSIY F+ A P F QG AI Sbjct: 417 QWQVIRMLSEEFFSGLGQRNVQRTLFAVGDEKQSIYSFQGAVPDDFA-------EQGRAI 469 Query: 498 LRANQTRRNATAVVDVLNRSFVMGGNPLFSQQTTLGLAGGEVWRLPLARPDDGAENVSSA 557 + NA + ++ +F P Q A EV+ P A V SA Sbjct: 470 ---SIQASNAELKFERVSLNFSFRSTPDVLQ------AVDEVFARPEANRGLSGATVHSA 520 Query: 558 DPDAASA--------APEGEQEVIPWRNP---LTTPRGEEDDARRLLEGQALAQALLKAY 606 D PE +E WR P L P A RL E Q A Sbjct: 521 IRDKEPGEIEIWDMLTPEMVEEPDDWRVPVDQLAAP------AVRLAE-QIAATIRYWLD 573 Query: 607 REVPVVEGKGARSMRWGDIMLLVRKRTH-LAAYESALRAAGIPFISDKRGGLLESLEIAD 665 R P + G+ R + DIM+LVRKR + A AL+ +P R L + I D Sbjct: 574 RGEP-IPGQN-RKIAPRDIMVLVRKRDQFMPALSRALKNLSVPVAGADRLQLTSHIAIQD 631 Query: 666 LIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGGHWWQQLQAMQQEGA 725 L+AL F++ P+D +LA +LKSP+ DD L +A + G ++ L + A Sbjct: 632 LMALGRFVLQPSDDLSLAALLKSPLFGWDDDRLFTLA--YPRGAGDTLFEYLYRASRHDA 689 Query: 726 ASAALVRAVTLLQRWLLAAPHLPVHDLLDMILH----QGELVAHYAQHASPLTRSQTLGN 781 A + + LL RW A +PV + +L + +L+A A + Sbjct: 690 ELAQIHK---LLSRWRNMADTMPVFEFYARVLSADGARRKLLARLGPEAGDI-------- 738 Query: 782 IAAFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPD-EASVDASADAVRILTVHSAK 840 I F +L+ + P L F++ L AP+ + +D D VRI+TVH+AK Sbjct: 739 IDEFQNYALSAERAGLPGLQAFLETLEAA-------APEIKRELDQGRDEVRIMTVHAAK 791 Query: 841 GLEAPVVAILDANHSDSVEDNLGILCAWPQDEDAPTHFSAFGRRSERGSARDPLFEEEET 900 GLE VV ++D + L + D P F + E E Sbjct: 792 GLEGAVVFLVDPGSAVWTGSRAPKLIPYDFQGDGPP-VKGFLWQPNSSCQTGFTAAEIEK 850 Query: 901 L--RTQEDW-NLLYVAVTRAKQLLLVSGVAGTRGAGAG-----------------GVVQG 940 L R +E++ LLYV +TRA+ L++ G GTR +G V G Sbjct: 851 LKNRAEEEYRRLLYVGMTRAEDRLIICGYRGTRESGETWHRLVEDALAAKSETFVHPVTG 910 Query: 941 SWYQRLFASDAPVREISEEAVHGAEAA-----DIEERFSLALFDPRPLPMS----LFGAP 991 +R + EI+EE GA + D + PRPL S L A Sbjct: 911 VAARRYRKTPRSFIEINEEDQAGATSLPPLPHDYRQPMKAEPGLPRPLAPSGASALIEAD 970 Query: 992 ADDPQDAVPALTADGALVSTDAIDEGVALHALLERLTHGHAWPLHVPSASVLVR----WL 1047 + P D + G A+ G A+H LL+ L +A L R W Sbjct: 971 EEPPLDLSSPVLQPGTGAPAFALRRGTAIHMLLQYLPDVAPEKREHLAADYLARIAADWP 1030 Query: 1048 GISAEMA-QVVHAQAREVLAQPQLERFFNPALHRWARNEMEIVTPNGLM----------- 1095 A Q VHA +L P+ F P +R E+ ++ G++ Sbjct: 1031 DAERLKAWQSVHA----ILDDPR----FGPVFAEGSRGEVAVM---GMIDIGGRDHAVSG 1079 Query: 1096 RLDRVVMFDDELWVIDYKR-----RLLDSERADYAAQLGRYRSALMSVFSDKQIRSALIT 1150 ++DR+ + + + ++DYK + L++ + Y AQL YR L ++ + + +AL+ Sbjct: 1080 QIDRISVDESRVLIVDYKTNRPPPKTLEAVPSAYRAQLALYRELLRPLYPGRVVEAALLF 1139 Query: 1151 AEGALI 1156 EG + Sbjct: 1140 TEGPFL 1145 >SMc02760 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Sme Sinorhizobium meliloti Length = 1189 Score = 218 bits (554), Expect = 8e-56, Method: Compositional matrix adjust. Identities = 332/1219 (27%), Positives = 502/1219 (41%), Gaps = 163/1219 (13%) Query: 27 ACDPRHSVVVEACAGSGKTWLLVARMLRLLLAGAQAPELLAITFTRKAAQEMRERLLELL 86 A DP S V A AGSGKT +L R++RLLLAG + +L +T+T+ AA EM R+ E L Sbjct: 27 ASDPACSAWVSANAGSGKTHVLTQRVIRLLLAGCRPSAILCLTYTKAAASEMSNRVFEKL 86 Query: 87 HELALADEAGAAALLRERGVAEPDLPRLLPLARGLYERILSSEQSLSIDTFHSWFARLLQ 146 E A D+ + P ++ AR L+ R L + L I T H++ LL Sbjct: 87 AEWATLDDTTLEKRIEAIEGKRPPTAKIQE-ARRLFARALETPGGLKIQTIHAFCEALLH 145 Query: 147 IAPLASGVPHGYTLTEKNGE--LLDEAYRRFMQTLREPEGAHIKAALLELYELAGDFNAR 204 PL + V +++ + LL +A R + + A + +LA D Sbjct: 146 QFPLEANVAGHFSVLDDRAAAVLLADARRALLTATAAASDGELAEAFATVLDLADDTGLE 205 Query: 205 QLLDAFIDKRAEWWAATQDDDQEDEEGAEEHAAPAPLRWLQALCGADAQRDARLSLWEEH 264 +LL A + RA A D G E H LR L + ++W Sbjct: 206 KLLAAIVANRAPIQAFL--DHASGRGGMEAH-----LRAALGLEPGETAGTVMAAVWPLA 258 Query: 265 ALVARPSQLAILLG--QGGSANQARAVAIESALSAGPALEHFDALYSQFFDDKDKPRKNG 322 L I LG GG+ A A + + + A + L FF+ KP+ Sbjct: 259 GLNGPALDDYIDLGLRLGGAKPSAIADGLRAVRAIDDAATRYSKLVELFFNGGGKPKAE- 317 Query: 323 KVKSLLAALVQHFEASEDAALAAFEAEFNAVGEALRKLQGRSKEKDVLQLNAALFTAGRA 382 + L A ++ AA + E V EA + ++Q ++ A RA Sbjct: 318 --SAFLNAAMRR---------AAPQLELR-VEEARSHMLACVDRLSIVQ----MYGATRA 361 Query: 383 YLAC-------YQEVKAEQRVLDFADLEWQAYRLLRNEASAAYLQTRLDARYKHILLDEF 435 L Y+ +K + LDF DL + LL A++ +LD HIL+DE Sbjct: 362 ALVLAERLNRDYEALKKARSQLDFEDLIHRTAALLARSDVGAWVHYKLDQGIDHILVDEA 421 Query: 436 QDTNPLQWCIVRCW-LDAYGGDAAQP---SVFVVGDPKQSIYRFRRAEPRVF----VAAR 487 QDT+P QW I++ D + G+ A+ ++F VGD KQSIY F+ A P F Sbjct: 422 QDTSPAQWTIIQSLAADFFAGETARADDRTIFAVGDEKQSIYSFQGARPERFSRESTLTE 481 Query: 488 EMLRAQGAAI--LRANQTRRNATAVVDVLNRSFVMGGN---------PLFSQQTTLGLAG 536 +RA +R + R+ V+ ++ F GN + +G G Sbjct: 482 RRVRAGNKHFSPIRLQLSFRSTVDVLSAVDTVFANPGNARGLSARSEAIVHASNRIGQPG 541 Query: 537 G-EVWRLPLARPDDGAENVSSADPDAASAAPEGEQEVIPWRNPLTTPRGEEDDARRLLEG 595 ++W +V + +P A+ + P R P+ ARR+ Sbjct: 542 AVDLW------------DVIAPEPAASEEDWTAPFDATPERAPVNIL------ARRI--- 580 Query: 596 QALAQALLKAY--REVPVVEGKGARSMRWGDIMLLVRKR-THLAAYESALRAAG-IPFIS 651 A+L+ + RE V+E R+MR GD+++LVRKR + A AL+ G IP Sbjct: 581 ----AAVLEDWIGRET-VIEKGVRRAMRPGDVIVLVRKRDAFVNALTRALKRRGNIPVAG 635 Query: 652 DKRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGG 711 R L + + DLIAL F++ P D +LA +LKSP++ ++D+ ++A R + EG Sbjct: 636 ADRLVLTSHIAVQDLIALGRFVLLPEDDLSLAALLKSPLLDLGEEDVFELAAR--RTEGE 693 Query: 712 HWWQQLQAMQQEGAASAALVR-AVTLLQRWLLAAPHLPVHDLLDMILH-QGELVAHYAQH 769 W++L +Q GA + AV L R+ A L HD +L G A A+ Sbjct: 694 SLWRRL---RQAGAEETSRYHEAVRTLSRYSGLARELLPHDFYARVLGADGGRRAFLARL 750 Query: 770 ASPLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPD-EASVDASA 828 S ++ + F+ +L+ + P L FI L + +AP + D Sbjct: 751 GSEVS-----DILDEFLTFALDHERNGLPGLQAFISTLEI-------EAPTVKREQDKER 798 Query: 829 DAVRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDEDAPTHFSAFGRRSERG 888 D VR++TVH+AKGLEAPVV ++D V + L + + + + R+ G Sbjct: 799 DEVRVMTVHAAKGLEAPVVFLVDGGGEAFVRQQVSDLRFLEKAQVDHSTLTVPVWRAP-G 857 Query: 889 SARDPLF----EEEETLRTQEDWNLLYVAVTRAKQLLLVSGVAGTRGAGAG--GVVQGSW 942 SA + L E + L +E LLYV +TRA L+V G G R +VQG+ Sbjct: 858 SAPNSLIAADNERLKKLAEEEYRRLLYVGMTRAADRLIVCGYRGQRQNTDTWHSMVQGTL 917 Query: 943 YQRLFASDAP--VREISEE--AVHGAEA---ADIEERFSLALFDPRP---LPMSLFGAPA 992 Q L P R SEE + EA D+ + RP LP +LF PA Sbjct: 918 AQDLKGRGTPRLFRAGSEEWQGIAWREAHVPRDLPTSEGRSEESQRPTAGLPTALFTPPA 977 Query: 993 DDPQDAVPALTADGALVSTDAID-EGVALHALLERLTHGHAWP-LHVPSASVLVRWLGI- 1049 P+ L G ++ D D E + AL G + P + ++L R L + Sbjct: 978 -APRRLPRPLAPSGTTIAIDDPDAEAIVGSALFA----GKSAPKFSMLRGAILHRLLQVL 1032 Query: 1050 -----SAEMAQVVHAQAREVLAQPQLERF--------------FNPALHRWARNEMEIVT 1090 +A AR V P+ ER P +R E+ ++ Sbjct: 1033 PSVDGPERLAAAERYLARSVPRWPEAERRALAGTVMDVLDHADLQPLFGEHSRAEVSVMG 1092 Query: 1091 PNGL--------MRLDRVVMFDDELWVIDYKRRLLDSERAD-----YAAQLGRYRSALMS 1137 L R+DR+ + D + + DYK E + Y QL YR L Sbjct: 1093 TLKLGVREFAVSGRIDRLAVTGDMVTIADYKTNREIPETPEEIAPVYRNQLAIYRELLKP 1152 Query: 1138 VFSDKQIRSALITAEGALI 1156 ++ K+ R LI EG I Sbjct: 1153 LYPGKRFRCVLIFTEGPAI 1171 >AGc39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1233 Score = 167 bits (424), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 171/587 (29%), Positives = 278/587 (47%), Gaps = 77/587 (13%) Query: 373 NAALFTAGRAYLACYQEVKAEQRVLDFADLEWQAYRLLRNEASAAYLQTRLDARYKHILL 432 +AL A R + ++++K ++ LDF DL +A LL + + A++ +LD HIL+ Sbjct: 410 KSALVLAER-LIGDFEDLKKQRSQLDFEDLIERAANLLNRDTAGAWVHYKLDQGIDHILV 468 Query: 433 DEFQDTNPLQWCIVRCW-LDAYGGDAA---QPSVFVVGDPKQSIYRFRRAEPRVFVAARE 488 DE QDT+P+QW I++ D + G++A + ++F VGD KQSIY F+ A P F R Sbjct: 469 DEAQDTSPVQWSIIQSLAADFFNGESARMGRRTLFAVGDEKQSIYSFQGARPERFSQER- 527 Query: 489 MLRAQGAAILRANQTRRNATAVVDVLNRSFVMGGNPLFSQQTTLGLAG-GEVWRLP---- 543 ++T+R VD + ++F PL + T LA +V+ P Sbjct: 528 ------------DETKRR----VDQVEQAFHRIRLPLSFRSTEDVLAAVDQVFSDPKNAS 571 Query: 544 -LARPDDGAENVSS--ADPDAAS----AAPEGEQEVIPWRNPLTTPRGEEDDARRLLEGQ 596 L+ ++ E+ S+ P APE ++ W P R + A + + Sbjct: 572 GLSADNEPVEHRSNRAGHPGTVEVWDMVAPETTEDEEDWTAPFDALR---ESAPATIVAR 628 Query: 597 ALAQALLKAYREVPVVEGKGARSMRWGDIMLLVRKRTHLAAYESAL-----RAAGIPFIS 651 +A + ++E R++ GDI++LVRKR AA+ +AL R IP Sbjct: 629 RIAARIADMIGNQTIIEKGVERAVEPGDILVLVRKR---AAFVNALTRELKRRKNIPVAG 685 Query: 652 DKRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGG 711 R L + + + DL+AL F++ P D +LA +LKSP+ + T+DD+ +IA A ++E Sbjct: 686 ADRLRLTDHIAVQDLLALGRFVVLPEDDLSLAALLKSPLFNLTEDDVFEIA--ATRSEAE 743 Query: 712 HWWQQLQAMQQEGAASAALVRAVTLLQRWLLAAPHLPVHDLLD--MILHQG--ELVAHYA 767 WQ+LQ + E + ++V L+ ++ + VHD + LH G + + Sbjct: 744 SVWQRLQVLSGEETSRLSIV--TDKLRHFISLSKTATVHDFFAAVLTLHDGRKKFLGRLG 801 Query: 768 QHASPLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPD-EASVDA 826 AS + + F+ +L+ + P L F+ L D+P+ + D Sbjct: 802 NEASDV--------LDEFLSFALDHERTGLPGLQAFLSVLET-------DSPEVKREQDK 846 Query: 827 SADAVRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDEDAPTHFSAFGRRSE 886 VRI+TVH++KGLEAPVV ++D ++ L D DA F + S Sbjct: 847 DRGEVRIMTVHASKGLEAPVVFVVDGGSKAFNHSHVPKLRFVEGDGDA---FPVWLPGS- 902 Query: 887 RGSARDPLFEEEETLRT---QEDWNLLYVAVTRAKQLLLVSGVAGTR 930 G + + +EE L+T E LLYVA+TRA L+V G G + Sbjct: 903 -GFSNHLIRSDEERLKTAAEDEYRRLLYVAMTRAADHLVVCGYRGQK 948 Score = 82.8 bits (203), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 65/196 (33%), Positives = 99/196 (50%), Gaps = 9/196 (4%) Query: 25 RAACDPRHSVVVEACAGSGKTWLLVARMLRLLLAGAQAPELLAITFTRKAAQEMRERLLE 84 R A DP S V A AGSGKT +L R++RLLLAG + +L +T+T+ AA EM R+ + Sbjct: 75 RLASDPASSAWVSANAGSGKTHVLTQRVIRLLLAGCRPSAILCLTYTKAAASEMSSRVFD 134 Query: 85 LLHELALADEAGAAALLRER-GVAEPDLPRLLPL--ARGLYERILSSEQSLSIDTFHSWF 141 L E A ++ L++R E +P + L AR L+ + L + L I T H++ Sbjct: 135 RLAEWATLPDSD----LKDRITTIEGKVPDRIKLAEARRLFAKALETPGGLKIQTIHAFC 190 Query: 142 ARLLQIAPLASGVPHGYTLTEKNG--ELLDEAYRRFMQTLREPEGAHIKAALLELYELAG 199 LL PL + V +++ + LL EA R + + + A + AL + +LA Sbjct: 191 EALLHQFPLEANVAGHFSVLDDRAATTLLAEARRSLLTAVSTEDDAELVQALAYVLDLAD 250 Query: 200 DFNARQLLDAFIDKRA 215 + LL A I R+ Sbjct: 251 ESGLEALLSAIIANRS 266 >BS_addA [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Bsu Bacillus subtilis Length = 1232 Score = 163 bits (412), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 237/967 (24%), Positives = 400/967 (41%), Gaps = 181/967 (18%) Query: 32 HSVVVEACAGSGKTWLLVARMLRLLLAGAQ---APELLAITFTRKAAQEMRERLLELLHE 88 ++V A AGSGKT +LV RM+R + A LL +TFT +A EM+ R+ E L E Sbjct: 24 QDILVAAAAGSGKTAVLVERMIRKITAEENPIDVDRLLVVTFTNASAAEMKHRIAEAL-E 82 Query: 89 LALADEAGAAALLRERGVAEPDLPRLLPLARGLYERILSSEQSLSIDTFHSWFARLLQIA 148 L G+ + R+ LS SI T HS+ ++L+ Sbjct: 83 KELVQRPGSLHIRRQ----------------------LSLLNRASISTLHSFCLQVLKKY 120 Query: 149 PLASGVPHGYTLTEKN-GELLDEAYRRFMQTLREPEGAHIKAALLELYELAGDFNARQLL 207 + G+ + ++ GEL+ + + L E E A + A EL + R L Sbjct: 121 YYLIDLDPGFRIADQTEGELIGD---EVLDELFEDEYAKGEKAFFELVDRYT--TDRHDL 175 Query: 208 D-AFIDKRAEWWAATQDDDQEDEEGAEEHAAPAPLRWLQALCG-ADAQRDARLSLWEEHA 265 D F+ K+ ++ + P P WL++ D + + + Sbjct: 176 DLQFLVKQVYEYSRSH---------------PNPEAWLESFVHLYDVSEKSAIEELPFYQ 220 Query: 266 LVARPSQLAILLGQGGSANQARAVAIESALSAGPA----------------LEH---FDA 306 V +A++L G RA+ + A GPA ++H F Sbjct: 221 YVK--EDIAMVLN-GAKEKLLRALELTKA-PGGPAPRADNFLDDLAQIDELIQHQDDFSE 276 Query: 307 LYSQF---------------FD----DKDKPRKNGKVKSLLAALVQHFEASEDAALAAFE 347 LY + FD D+ +NG K L +F S + L + Sbjct: 277 LYKRVPAVSFKRAKAVKGDEFDPALLDEATDLRNGAKKLLEKLKTDYFTRSPEQHLKSL- 335 Query: 348 AEFNAVGEALRKLQGRSKEKDVLQLNAALFTAGRAYLACYQEVKAEQRVLDFADLEWQAY 407 AE V E L +L + + G+ + A K E+ ++DF+DLE Sbjct: 336 AEMKPVIETLVQL---------------VISYGKRFEAA----KQEKSIIDFSDLEHYCL 376 Query: 408 RLLRNEASAAYLQTRLDARY-----KHILLDEFQDTNPLQWCIVRCWLDAYGGDAAQPSV 462 +L E + AR+ +L+DE+QDTN +Q I++ G ++ Sbjct: 377 AILTAENDKGEREPSEAARFYQEQFHEVLVDEYQDTNLVQESILQL---VTSGPEETGNL 433 Query: 463 FVVGDPKQSIYRFRRAEPRVFVAAREMLRAQGAAILRANQTRRNATAVVDVLNRSFVMGG 522 F+VGD KQSIYRFR AEP +F++ + G R +N + D+L+ + Sbjct: 434 FMVGDVKQSIYRFRLAEPLLFLSKYKRFTESGEGTGRKIDLNKNFRSRADILDST----- 488 Query: 523 NPLFSQQTTLGLAGGEVWRLPLARPDDGAE-NVSSADPDAASAAPEGEQEVIPWRNPLTT 581 N LF Q L GG++ + D+ AE + +A PD E E E++ N T Sbjct: 489 NFLFKQ-----LMGGKIGEVDY---DEQAELKLGAAYPDN----DETETELLLIDNAEDT 536 Query: 582 PRGEEDDARRLLEGQALAQALLKAYREV-----PVVEGKGA--RSMRWGDIMLLVRKRTH 634 EE A L Q A+A+ K R++ V +GK R++++ DI++L+R Sbjct: 537 DASEE--AEELETVQFEAKAIAKEIRKLISSPFKVYDGKKKTHRNIQYRDIVILLRSMPW 594 Query: 635 LAAYESALRAAGIPFISDKRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIISAT 694 LRA GIP ++ G E++E+A +++L + P LA VL+SPI+ A Sbjct: 595 APQIMEELRAQGIPVYANLTSGYFEAVEVAVALSVLKVIDNPYQDIPLASVLRSPIVGAD 654 Query: 695 DDDLVQIARRAAQAEGGHWWQQLQAMQQEGAASAALVRAVTL----LQRWLLAAPHLPVH 750 +++L I +A +++ ++ G S L + + LQ+W + + V Sbjct: 655 ENELSLIRLENKKAP---YYEAMKDYLAAGDRSDELYQKLNTFYGHLQKWRAFSKNHSVS 711 Query: 751 DLLDMILHQGELVAHYAQHASPLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVL 810 +L+ + + + + R N+ + + ++ + L +F+ + + Sbjct: 712 ELIWEVYRDTKYMDYVGGMPGGKQRQ---ANLRVLYDRARQYESTAFRGLFRFLRFIERM 768 Query: 811 QRSAGGDAPDEASVDASADAVRILTVHSAKGLEAPVVAI---------LDANHSDSVEDN 861 Q G D + D VR++T+HS+KGLE PVV + +D N S ++ Sbjct: 769 QER-GDDLGTARGLSEQEDVVRLMTIHSSKGLEFPVVFVAGLGRNFNMMDLNKSYLLDKE 827 Query: 862 LGILCAWPQDEDAPTHFSAFGRRSERGSARDPLFEEEETLRTQ---EDWNLLYVAVTRAK 918 LG + + ++ + PL ++ +R + E+ +LYVA+TRAK Sbjct: 828 LGFGTKYIHPQLRISYPTL------------PLIAMKKKMRRELLSEELRVLYVALTRAK 875 Query: 919 QLLLVSG 925 + L + G Sbjct: 876 EKLFLIG 882 >BH2980 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Bha Bacillus halodurans Length = 1129 Score = 162 bits (409), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 249/963 (25%), Positives = 394/963 (40%), Gaps = 190/963 (19%) Query: 19 DAAVFTRAACDPRHSVVVEACAGSGKTWLLVARMLRLLLA-------------GAQAPEL 65 + A+F+RA VV+ A AGSGKT +L R + + GA+ EL Sbjct: 10 EQAIFSRAPL-----VVLSAGAGSGKTRVLTERFVHICEQKWQETQNDLEASFGAEVDEL 64 Query: 66 LAITFTRKAAQEMRER----LLELLHELALADEAGAAALLRERGVAEPDLPRLLPLARGL 121 +AITFT KAA+EM+ER LLE + E +AG +++ GL Sbjct: 65 VAITFTEKAAREMKERIRQRLLEKVEEAKAHGDAGQMIFWQKQ-------------KEGL 111 Query: 122 YERILSSEQSLSIDTFHSWFARLLQIAPLASGVPHGYTLTEK------NGELLDEAYRR- 174 + I TFHS+ RLL +G+P + + ++ E+LD+ ++ Sbjct: 112 --------ERARISTFHSFCQRLLLEYAQEAGIPPTFIVLDEVEAAIMKREILDDLFQDA 163 Query: 175 -----FMQTLREPEGAHIKAALLELYELAGDFNARQLLDAFIDKRAEWWAATQDDDQEDE 229 F + L ++++LL++YE D +A DDD Sbjct: 164 LLRPLFAKLLECYTKRSLESSLLQVYEHIRDIHA-------------------DDDV--- 201 Query: 230 EGAEEHAAPAPLRWLQALCGADAQRDARLSLWEEHALVARPSQLAILLGQGGSANQARAV 289 + L G DA L++ + HAL+ Q + + S R Sbjct: 202 --------------FKRLDG-----DAMLNV-QTHALLLEKEQQIAVFHEKASRLVDRID 241 Query: 290 AIESALSAGPALEHFDALYSQFFD-DKDKPRKNGKVKSLLAALVQHFEASEDAALAAFEA 348 + +L+ +H L S F + + P + V++L AA+ S AF+ Sbjct: 242 GNDPSLTKALK-DHIHNLLSCFHQLNPEAP--DLYVQTLTAAMPARGHKSWGEKAPAFQQ 298 Query: 349 EFNAVGEALRK------LQGRSKEKDVLQLNAALFTAGRAYLACYQEVKAEQRVLDFADL 402 ++ + L+K ++ + K+VL A + + A Y+E K DF+DL Sbjct: 299 LYDE-WKGLKKHWTSFSVEVQPITKEVL---TAFIDLLQYFAARYKERKQLLSAFDFSDL 354 Query: 403 EWQAYRLLRNEASAAYLQTRLDARYKHILLDEFQDTNPLQWCIVRCWLDAYGGDAAQPSV 462 + A LL E +Q ++KH+++DEFQDTN +Q ++ +Y Sbjct: 355 QRNAVCLLDQED----VQKSCHDQFKHMMVDEFQDTNQMQMDVLTKINPSYQ-------- 402 Query: 463 FVVGDPKQSIYRFRRAEPRVFVAAREMLRAQGAAILRANQTRRNATAVVDVLNRSFVMGG 522 F+VGD KQSIYRFR A+ + E R + A T TA V + Sbjct: 403 FLVGDGKQSIYRFRGADVTLMNEMSEQARDEKEAQFIEMNTNYRTTAPV-------IHAV 455 Query: 523 NPLFSQQTTLGLAGGEVWRLPLARPDDGAENVSSADPDAASAAPEGEQEVIPWRNPLTTP 582 N LF+ + V +P A S P + PE E ++ + T Sbjct: 456 NGLFAH----AMKDVSVHSVPYA----------SLIP---AREPEKEDDIRVSLHITKTT 498 Query: 583 RGEEDDARRLLEGQALAQALLKAYR--EVPVVEGKGARSMRWGDIMLLVRKRTHLAAYES 640 E+D+ + + +A LL+ R E V G+ RS WGD+ +L+ RT L A E Sbjct: 499 EKEKDNDQ--VPYHHIADRLLEMVRTGEPTVWNGESWRSPNWGDMAILIPVRTELLALER 556 Query: 641 ALRAAGIPFISDKRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQ 700 AL GIP+ G E EI D + LL +L P + L +L+SP+ T DDL+ Sbjct: 557 ALSDKGIPYHVYGGVGFYERQEILDFVTLLRWLDRPFEELYLFALLRSPMFGLTLDDLMF 616 Query: 701 IARRAAQAEGGHWW------QQLQAMQQEGAASAALVRAVTLLQRWLLAAPHLPVHDLLD 754 + R ++ W+ + + + A VR T L RW+ P PV L+D Sbjct: 617 VKERF--SDELTWFDIVVDKEMASLFAERPVVTDAFVRLRTWLDRWV---PFRPVPSLID 671 Query: 755 MILHQGELVAHYAQHASPLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRSA 814 H EL S + + + +L M + L + + ++Q A Sbjct: 672 ---HLYELFDQTGLKMSLFVQENGMQKVRNVEKLIDVMSGWKTNVLEELLQRFDLIQ--A 726 Query: 815 GGDAPDEASVDASA-DAVRILTVHSAKGLEAPVVAILDANHSDS-------VEDNLGILC 866 + EA V+ A + V I+TVH++KGLE P+V + + + +GI+ Sbjct: 727 EVEKEGEAEVEQVAGNVVHIMTVHASKGLEFPIVCLPQLDRVPQRDKGQVRYDREMGIVL 786 Query: 867 --AWPQDED-APTHFSAFGRRSERGSARDPLFEEEETLRTQ-EDWNLLYVAVTRAKQLLL 922 W +D+ AF L +E+ L T E+ L YVA TRA+ L Sbjct: 787 RHEWEEDDGVVKLETPAFA-----------LVKEQADLATMAENKRLFYVAATRARDYLW 835 Query: 923 VSG 925 ++G Sbjct: 836 MTG 838 >mll5083 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Mlo Mesorhizobium loti Length = 1170 Score = 157 bits (397), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 242/888 (27%), Positives = 369/888 (41%), Gaps = 176/888 (19%) Query: 369 VLQLNAALFTAGRAYLACYQEVKAEQRVLDFADLEWQAYRLLRNEASAAYLQTRLDARYK 428 +L+ A T +A Y +K + LDF DL + LL + ++Q +LD Sbjct: 344 MLEGTRAALTIADWLIARYDVLKRSRGFLDFNDLITRTVNLLARPDAGPWVQYKLDQGID 403 Query: 429 HILLDEFQDTNPLQWCIVRC----WLDAYGG-DAAQPSVFVVGDPKQSIYRFRRAEPRVF 483 HILLDE QDT+P QW +V+ + +G D +VF VGD KQSIY F+ A P F Sbjct: 404 HILLDEAQDTSPDQWEVVKRLAEEFFAGFGARDRVHRTVFAVGDEKQSIYSFQGAAPDSF 463 Query: 484 VAAREML--RAQGA----AILRANQTRRNATAVVDVLNRSF----VMGG-----NPLFSQ 528 +R + R + A A L+ + R+ V+ ++R F V G +PL + Sbjct: 464 ADSRLLFAGRVRDAEASFADLKLTWSFRSTDDVLAAVDRVFADPVVRRGISHDPDPLSHK 523 Query: 529 QTTLGLAGG-EVWRLPLA----RPDDGAENVSSADPDAASAAPEGEQEVIPWRNPLTTPR 583 G EVW A PDD A+ + A A A + W + Sbjct: 524 AIRTDAPGYVEVWPSIGADVVDEPDDWAQAIDHAHAPAVRVAENVAATIAGWIG-----K 578 Query: 584 GEEDDARRLLEGQALAQALLKAYREVPVVEGKGARSMRWGDIMLLVRKR-THLAAYESAL 642 GE ++EG+G R +R GD+++LVRKR + + A AL Sbjct: 579 GE-------------------------IIEGRGKR-LRPGDVLVLVRKRDSFVHALTRAL 612 Query: 643 RAAGIPFISDKRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIA 702 + IP R L + + DLIAL L+ P D +LA VL+SPI ++ L + Sbjct: 613 KRRDIPVAGADRLSLPGHIAVKDLIALGHLLLQPQDDLSLAAVLRSPIFDLPEEALFTL- 671 Query: 703 RRAAQAEGGHWWQQLQAMQQEGAASAALVRAVTLLQRWLLAAPHLPVHDLLDMILHQGEL 762 AAQ G +++Q S L + V L W A PV +L +L + ++ Sbjct: 672 --AAQRPPG--LSLAASLRQHAGESERLAKIVAQLDAWADEAAFKPVFELYAGLLARDDV 727 Query: 763 VAHYAQHASPLTRSQTLGNIA-AFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPDE 821 P G+I F+ L + P L F+ L +AG + E Sbjct: 728 RKRMIARLGP-----EAGDILDEFLSFCLAEERTGLPGLEAFLSTL----ENAGPEIKRE 778 Query: 822 ASVDASADAVRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDEDAPTHFSAF 881 +D + D VR++TVH+AKGLEAPVV ++D + + +L L ++ + +F Sbjct: 779 --MDQTRDEVRVMTVHAAKGLEAPVVFLVDGGSAPFSDQHLPRLMSF---GGSGRNFDGK 833 Query: 882 GRRSERGSARDPLFEEEETLRTQEDWN-----LLYVAVTRAKQLLLVSGVAGTRGAGAGG 936 G S F + R +E + LLYV +TRA+ L+V G G R Sbjct: 834 GYLWRSASDVANGFSKAAATRARELADDEYRRLLYVGMTRAEDRLIVCGYHGKRAPNT-- 891 Query: 937 VVQGSWYQRLFASDAPVREISE-------EAVHG---------AEAADIEERFSLAL--- 977 G+W+ + + EI + E VH A +AD + R + A Sbjct: 892 ---GTWHSIVSRALTGAPEIEQRPHPAGGEPVHRFHVTRLPPVAVSADEQARQADAFGPL 948 Query: 978 ----------FDPRPLPMSLFGAPA--DDPQDAV-----PALTADGALVSTDAIDEGVAL 1020 F+ P P+S GA A D+ ++AV P L AD A+ G+AL Sbjct: 949 PATLFRPLPPFEDLPRPLSPSGASALIDEGKEAVVDKASPVLDADAE--PGFAVLRGLAL 1006 Query: 1021 HALLERLT-----------------HGHAWPLHVPSASVLVRWLGISAEMAQVVHAQARE 1063 H LL+ L G AWP PS +A V+ Sbjct: 1007 HKLLQVLPGIAEGERQGAAERYLARTGAAWP---PSER--------EKALASVI-----A 1050 Query: 1064 VLAQPQLERFFNPALHRWARNEMEIV--------TPNGLMRLDRVVMFDDELWVIDYKRR 1115 +L P+L + F AL +R E+ I+ T + ++DR+ + + + ++DYK Sbjct: 1051 ILVDPRLGQLF--ALS--SRAEVAIMGSLQVRGKTRSISGKIDRLAVTANTVSIVDYKTN 1106 Query: 1116 L-----LDSERADYAAQLGRYRSALMSVFSDKQIRSALITAEGA-LIE 1157 L Y QL YR+ L ++ +++++AL+ E LIE Sbjct: 1107 RPAPVSLAEVPPAYLLQLALYRALLQPLYPGREVKAALLFTEAPRLIE 1154 Score = 73.9 bits (180), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 59/189 (31%), Positives = 88/189 (46%), Gaps = 2/189 (1%) Query: 27 ACDPRHSVVVEACAGSGKTWLLVARMLRLLLAGAQAPELLAITFTRKAAQEMRERLLELL 86 A DP++S V A AGSGKT +L R++RLLL G ++L +T+TR AA M R+ L Sbjct: 18 AADPQNSAWVSANAGSGKTHVLAQRVIRLLLNGTDPSKILCLTYTRAAAANMSNRVFSTL 77 Query: 87 HELALADEAGAAALLRERGVAEPDLPRLLPLARGLYERILSSEQSLSIDTFHSWFARLLQ 146 E + +A AA + PD + AR L+ L + L I T H++ +L Sbjct: 78 SEWTVLGDAELAAKIEALEGRRPDRDTMR-RARRLFAEALETPGGLKIQTIHAFCESVLH 136 Query: 147 IAPLASGVPHGYTLTEKNGEL-LDEAYRRFMQTLREPEGAHIKAALLELYELAGDFNARQ 205 PL + +P + + + E L A RR M + + A + E G+ Sbjct: 137 QFPLEANIPAHFEMLDGQMEASLFAAARREMISGTAAGNPDLADAFATVLERGGEAGLDA 196 Query: 206 LLDAFIDKR 214 LL + KR Sbjct: 197 LLGEIVRKR 205 >SA0828 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Sau Staphylococcus aureus N315 Length = 1217 Score = 155 bits (393), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 242/950 (25%), Positives = 395/950 (41%), Gaps = 151/950 (15%) Query: 34 VVVEACAGSGKTWLLVARML-RLLLAGAQAPELLAITFTRKAAQEMRERLLELLHELALA 92 V+V A AGSGKT +LV R++ ++L G LL +TFT +A+EM+ R+ Sbjct: 27 VLVAAAAGSGKTAVLVERIIQKILRDGIDVDRLLVVTFTNLSAREMKHRV---------- 76 Query: 93 DEAGAAALLRERGVAEPDLPRLLPLARGLYERILSSEQSLSIDTFHSWFARLLQIAPLAS 152 ++E +A+P L +RI + +S T HS+ +L+Q Sbjct: 77 -----DQRIQEASIADPANAHLKN------QRIKIHQAQIS--TLHSFCLKLIQQHYDVL 123 Query: 153 GV-PHGYTLTEKNGELLDEAYRRFMQTLREPEGAH---IKAALLELYE-LAGDFNARQLL 207 + P+ T +E LL E QT+ E H + A +EL E L+ D + Q Sbjct: 124 NIDPNFRTSSEAENILLLE------QTIDEVIEQHYDILDPAFIELTEQLSSDRSDDQF- 176 Query: 208 DAFIDKRAEWWAATQDDDQEDEEGAEEHAAPAPLRWLQALCG---ADAQRDARLSLWEEH 264 I K+ +++ A P P WL L +AQ+ + L + Sbjct: 177 -RMIIKQLYFFSV---------------ANPNPTNWLDQLVTPYEEEAQQAQLIQLLTDL 220 Query: 265 ALVARP------SQLAILLGQGGSANQARAVAIESALSAGPALE--HFDALYSQFFDDKD 316 + V ++ L ++ AV + G LE D Y D + Sbjct: 221 SKVFITAAYDALNKAYDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPY---LTDHE 277 Query: 317 K----PRKNGKVKSLLAALVQHFEASEDAALAAFEAEFNAVGEALRKLQGR--SKEKDVL 370 P K+K +V +A EDA L ++ + K++ S+E D L Sbjct: 278 FGARLPNVTAKIKEANEMMV---DALEDAKL-----QYKKYKSLIDKVKNDYFSREADDL 329 Query: 371 QLNAALFTAGRAYLAC--------YQEVKAEQRVLDFADLEWQAYRLLRNE-ASAAYLQT 421 + + YLA + K + +LDF+D E A ++L NE S + + Sbjct: 330 KADMQQLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAE 389 Query: 422 RLDARYKHILLDEFQDTNPLQWCIVRCWLDAYGGDAAQPSVFVVGDPKQSIYRFRRAEPR 481 ++ IL+DE+QDTN +Q I+ C GD ++F+VGD KQSIY+FR+A+P Sbjct: 390 SYRQHFQEILVDEYQDTNRVQEKILSC---IKTGDEHNGNLFMVGDVKQSIYKFRQADPS 446 Query: 482 VFVAAREMLRAQGAAILRANQTRRNATAVVDVLNRSFVMGGNPLFSQQTTLGLAGGEVWR 541 +F+ + G R +N + +VL+ + N +F + GEV Sbjct: 447 LFIEKYQRFTIDGDGTGRRIDLSQNFRSRKEVLSTT-----NYIFKH--MMDEQVGEVKY 499 Query: 542 LPLARPDDGAENVSSADPDAASAAPEGEQEVIPWRNPLTTPRGEEDDARRLLEGQALAQA 601 A+ GA S P E +QE + LT G E +A ++E + Sbjct: 500 DEAAQLYYGAPYDESDHPVNLKVLVEADQE----HSDLT---GSEQEAHFIVEQ---VKD 549 Query: 602 LLKAYREVPVVEGKGARSMRWGDIMLLVRKRTHLAAYESALRAAGIPFISDKRGGLLESL 661 +L+ +++V ++ RS + DI++L R + A + IPF + R G E Sbjct: 550 ILE-HQKVYDMKTGSYRSATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQT 608 Query: 662 EIADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGGHWWQQLQAMQ 721 E+ +++ L + P L +++S I +D+L QI R +++Q + Sbjct: 609 EVRLVLSFLRAIDNPLQDIYLVGLMRSVIYQFKEDELAQI--RILSPNDDYFYQSIVNYI 666 Query: 722 QEGAASAALVRAVTL----LQRWLLAAPHLPVHDLLDMILHQGELVAHYA-QHASPLT-- 774 + AA A LV + + +Q + + PV+ L+D + HY Q+ S L Sbjct: 667 NDEAADAILVDKLKMFLSDIQSYQQYSKDHPVYQLIDKFYND-----HYVIQYFSGLIGG 721 Query: 775 ---RSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPDEASVDASADAV 831 R+ G +E + G Y + +FID L ++R G D +E V + + V Sbjct: 722 RGRRANLYGLFNKAIEFENSSFRGLYQFI-RFIDEL--IER--GKDFGEENVVGPNDNVV 776 Query: 832 RILTVHSAKGLEAPVVAI----LDANHSD-----SVEDNLGILCAWPQDEDAPTHFSAFG 882 R++T+HS+KGLE P V D N D + G+ + D D F + Sbjct: 777 RMMTIHSSKGLEFPFVIYSGLSKDFNKRDLKQPVILNQQFGLGMDYF-DVDKEMAFPSLA 835 Query: 883 RRSERGSARDPLFEEEETLRTQEDWNLLYVAVTRAK-QLLLVSGVAGTRG 931 + + A L EE L+YVA+TRAK QL L+ V + Sbjct: 836 SVAYKAVAEKELVSEE--------MRLVYVALTRAKEQLYLIGRVKNDKS 877 >RC1114 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Rco Rickettsia conorii Length = 822 Score = 145 bits (367), Expect = 5e-34, Method: Compositional matrix adjust. Identities = 154/587 (26%), Positives = 243/587 (41%), Gaps = 102/587 (17%) Query: 384 LACYQEVKAEQRVLDFADLEWQAYRLLRNEASAAYLQTRLDARYKHILLDEFQDTNPLQW 443 L Y K E +LD+ DL + +LL N+ + +L +L++ HIL+DE QDT+P QW Sbjct: 301 LKKYDSYKEENNLLDYDDLIYYTEKLLNNKTTHKWLLHKLESEINHILVDEAQDTSPSQW 360 Query: 444 CIVRCWLDAYGG-DAAQPSVFVVGDPKQSIYRFRRAEPRVFVAAREMLRAQGAAILRANQ 502 I+ + + + SVF+VGD KQSI+ F+ A+ R F E L+A + AN+ Sbjct: 361 NIITTLITEFNAVERPNNSVFIVGDDKQSIFSFQGADLRNFNLVNERLKAN---LTNANK 417 Query: 503 TRRNAT------AVVDVLNRSF-------------VMGGNPLFSQQTTLGLAGGEVWRLP 543 +N T + ++L ++ + NPL S T G V P Sbjct: 418 KFKNITLEYSYRSCTEILQFTYNVLKNIKSNYPGLFLSNNPLISSFRT---HQGSVTVWP 474 Query: 544 LARPDDGAENVSSADPDAASAAPEGEQEVIPWRNPLTTPRGEEDDARRLLEGQALAQALL 603 L + +QE + W P + A L+E + Sbjct: 475 LVTSE--------------------KQEELFWALP-EDYENSKSAADLLIEKIV---NFI 510 Query: 604 KAYREVPVVEGKGARSMRWGDIMLLVRKRTHLA-AYESALRAAGIPFISDKRGGLLESLE 662 K E + A + D M+LVRKR + L A + R L E+L Sbjct: 511 KEQIESEEILPSTAHRISEKDFMILVRKRDEFSNNLIKELSKAKLKVEVSDRMNLKENLT 570 Query: 663 IADLIALLTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGGHWWQQLQAMQQ 722 I DLI+L F++ P+D LA +LKSPII ++ L ++ ++ W L + ++ Sbjct: 571 IMDLISLAKFVLLPDDDLNLAGLLKSPIIGISEQQLYELLVNKSE---NSLWDILSSHEE 627 Query: 723 EGAASAALVRAVTLLQRWLLAAPHLPVHDLLDMILHQGELVAHYAQHASPLTRSQTLGNI 782 +L+ + V + D+++H L Y + + I Sbjct: 628 IYNKLDSLIEIYKI----------SIVENFFDLVVHNLNLRELYDDDSDDM--------I 669 Query: 783 AAFVELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPDEASVDASADAVRILTVHSAKGL 842 + LS N SL F+ D + ++ S D +R++TVH +KGL Sbjct: 670 NELLTLSKNYANDIDNSLQGFVAWFE------NNDIYIKRDIEHS-DKIRVMTVHGSKGL 722 Query: 843 EAPVVAILDANHSDSVEDNLGILCAWPQDEDAPTHFSAFGRRSERGSARDPLF----EEE 898 EAP+V + D+ + + N I W D+ FSA +A P F +E Sbjct: 723 EAPIVILCDST-TLPISSNKFI---W--DDKGEMFFSA-------NAADTPEFLQELKEA 769 Query: 899 ETLR-TQEDWNLLYVAVTRAKQLLLVSGVAGTRGAGAGGVVQGSWYQ 944 E L+ QE LLYVA+TRAK L++ G + + WY+ Sbjct: 770 EKLKDLQEYIRLLYVAMTRAKDRLIICGF-----SNKSTTPENCWYE 811 Score = 87.4 bits (215), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 53/140 (37%), Positives = 81/140 (57%), Gaps = 3/140 (2%) Query: 25 RAACDPRHSVVVEACAGSGKTWLLVARMLRLLLAGAQAPELLAITFTRKAAQEMRERLLE 84 R A DP +SV V A AG+GKT +L R LRLL+ G + +L +TFT AA EM+ R+ Sbjct: 6 REASDPNYSVWVSASAGTGKTKILTDRFLRLLITGVEPSNILCLTFTNAAAIEMQVRINS 65 Query: 85 LLHELALAD-EAGAAALLRERGVAEPDLPRLLPLARGLYERILSSEQSLSIDTFHSWFAR 143 L L+L + E AL G +P P+ A+ LY++IL+S + L+I T H++ + Sbjct: 66 RLKYLSLCNAEKLEEALFLMSG-NKPS-PQDTENAKTLYDKILNSNKLLNIYTIHAFCQK 123 Query: 144 LLQIAPLASGVPHGYTLTEK 163 +L PL +G+ + + E+ Sbjct: 124 ILNTFPLEAGITPEFKILEE 143 >lin2368 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Lin Listeria innocua Length = 1235 Score = 142 bits (357), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 145/566 (25%), Positives = 270/566 (47%), Gaps = 54/566 (9%) Query: 381 RAYLACYQEVKAEQRVLDFADLEWQAYRLLRNEASAAYLQTRLDARYKHILLDEFQDTNP 440 + + + E K ++ VLDF DLE A ++L + + + ++K +L+DE+QDTN Sbjct: 356 KKFAENFFEEKQQRGVLDFNDLEHLALKILLKNGAPSDVANSYKKQFKEVLIDEYQDTNM 415 Query: 441 LQWCIVRCWLDAYGGDAAQPSVFVVGDPKQSIYRFRRAEPRVFVAAREMLR--AQGAAI- 497 +Q I+ L + + ++F+VGD KQSIYRFR AEP +F+A + + +G+ I Sbjct: 416 VQETIL---LLVTNSNDTKGNLFMVGDVKQSIYRFRLAEPTLFMAKYQEYQQDGEGSGIR 472 Query: 498 LRANQTRRNATAVVDVLNRSFVMGGNPLFSQQTTLGLAGGEVWRLPLARPDDGAE-NVSS 556 + +Q R+ V+D N +F Q +A + D+ AE + + Sbjct: 473 IDLSQNFRSRKEVLD--------ATNFIFHQLMDKHIAEIDY--------DEAAELTLGA 516 Query: 557 ADPDAASAAPEGEQEVIPWRNPLTTPRGEEDDARRLLEGQALAQALLKAYREV-----PV 611 + P+A + A E ++ +E + L + Q ++A+ RE+ P+ Sbjct: 517 SFPEANNMATEL---LLIDMKSEEKESEDELSPQELQKNQVESRAIATKIREMIDNKFPI 573 Query: 612 VEGK--GARSMRWGDIMLLVRKRTHLAAYESALRAAGIPFISDKRGGLLESLEIADLIAL 669 + K R +++ DI++L R T E A++ IPF ++ G E+ E+A +IAL Sbjct: 574 YDKKLQQNRPIQYRDIVILARAMTSAPDMEEAMKIKDIPFYANNNSGYFETTEVATMIAL 633 Query: 670 LTFLITPNDTRALAHVLKSPIISATDDDLVQIARRAAQAEGGHWWQQLQAMQQEGAASAA 729 + + P +LA VL+SPII +++L QI R A+ + G+++ + A + + AA Sbjct: 634 MKVIDNPYQDISLAAVLRSPIIGLNEEELGQI--RMAKKK-GYFFDAMLAYKDITVSDAA 690 Query: 730 --LVRAVTLLQRWLLAAPHLPVHDLLDMILHQGELVAHYAQHASPLT-RSQTLGNIAAFV 786 + R +T L W L + + L ++ Q ++ + L Q N+ A Sbjct: 691 NKISRFITQLNNW----RELSIRENLTALIWQIYQETNFYEFVGGLPGGKQRQANLRALY 746 Query: 787 ELSLNMDAGRYPSLPKFIDALRVLQRSAGGDAPDEASVDASADAVRILTVHSAKGLEAPV 846 + + + + L +F+ + L+ G D ++ D VR++T+H++KGLE PV Sbjct: 747 DRANQYEKTSFRGLFRFVRFVERLE-VRGDDLGTAKTLGEKEDVVRMMTIHASKGLEFPV 805 Query: 847 VAILDANHSDSVEDNLGILCAWPQDEDAPTHFSAFGRRSERGSARDPLFEE---EETLRT 903 V + + ++ D I D+D F++ R E+ + ++ ++ R Sbjct: 806 VIVSGLSRKFNMRD---IYSKTLLDKDYG--FASNYRDIEKMIVYPTIMQQAIKQKKYRE 860 Query: 904 Q--EDWNLLYVAVTRAKQLLLVSGVA 927 E+ +LYVA+TRA++ L+++ Sbjct: 861 MIAEEMRVLYVALTRAEEKLILTATV 886