BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0161.p (336 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DRB0093 [T] COG2199 FOG Dra Deinococcus radiodurans 112 1e-24 AGc1815 [T] COG2199 FOG Atu Agrobacterium tumefaciens strain C58... 108 1e-23 AGl3494_3 [T] COG2199 FOG Atu Agrobacterium tumefaciens strain C... 108 2e-23 mll4839 [T] COG2199 FOG Mlo Mesorhizobium loti 107 4e-23 aq_035_2 [T] COG2199 FOG Aae Aquifex aeolicus 105 1e-22 TM0143 [T] COG3706 Response regulator containing a CheY-like rec... 105 1e-22 VC1599 [T] COG2199 FOG Vch Vibrio cholerae 104 2e-22 DR0267 [T] COG2199 FOG Dra Deinococcus radiodurans 103 5e-22 SMc04015 [T] COG2199 FOG Sme Sinorhizobium meliloti 103 8e-22 RC0321 [T] COG3706 Response regulator containing a CheY-like rec... 102 1e-21 >DRB0093 [T] COG2199 FOG Dra Deinococcus radiodurans Length = 364 Score = 112 bits (280), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 65/173 (37%), Positives = 98/173 (56%), Gaps = 6/173 (3%) Query: 164 VKRQHVESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFK 223 V + V S L +L + D LTG +RR ++L + + P LM+D+D+FK Sbjct: 191 VNEEQVRSAYLEGQLAW----DALTGTLSRRGLEKKLGTLWRTSSPEQTLLLMVDVDHFK 246 Query: 224 KINDDFGHASGDEALILTARAMQSALSEGAL-GRMGGEEFGIALSGGGLAHAEQVAAKLL 282 +ND +GH +GD+AL + +++A SE AL GR GGEEF + L +QV +LL Sbjct: 247 GVNDSYGHLTGDQALQMIGVTLRAAASEHALIGRWGGEEFVMVLPCQSAREHQQVTEQLL 306 Query: 283 QEVRQIHI-HARPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDRYVV 334 +R + + H PLT+S G A A+ S+ V++ AD LYQAK G++R V+ Sbjct: 307 HTIRTLRVDHLPPLTISAGGATFAEAPSLEAVIAMADSRLYQAKDGGRNRAVL 359 >AGc1815 [T] COG2199 FOG Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 346 Score = 108 bits (271), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 79/204 (38%), Positives = 108/204 (52%), Gaps = 9/204 (4%) Query: 142 DERWMLLLTLTVLGLGNFVNLT-VKRQHVESLRLRKELEFI---AFKDPLTGIDNRRRFM 197 D RWML T+ G +T V +E LR+E + A D LTG+ NRR M Sbjct: 140 DGRWMLTTETTLPGGWMLCVITDVSELGIELRDLRQERDRALKSALSDELTGLGNRRYAM 199 Query: 198 QQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALI-LTARAMQSALSEGALGR 256 L +L + +++DID+FK +ND FGHA GD L AR +A + LGR Sbjct: 200 DTLNHLLGPNKAQALAVIIMDIDHFKSVNDRFGHAYGDLVLKDFAARLSATAGRDDLLGR 259 Query: 257 MGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIH-IHARP---LTVSIGIARAADHSSVSK 312 +GGEEF + LSG + A+ + +LL + Q + RP + S GIA A S S+ Sbjct: 260 IGGEEFLLVLSGSRMHSADSLMRQLLSSLAQASPLGDRPDFRYSCSAGIAYANPGESASE 319 Query: 313 VLSAADQALYQAKRAGKDRYVVSA 336 VL AD ALY+AK G++RYV+ A Sbjct: 320 VLRHADTALYEAKNTGRNRYVIYA 343 >AGl3494_3 [T] COG2199 FOG Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 173 Score = 108 bits (270), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 69/171 (40%), Positives = 100/171 (58%), Gaps = 7/171 (4%) Query: 171 SLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFG 230 +L+LR+ L +A +D LTG+ NRR + L ++ S AC LM+DID+FK+ ND FG Sbjct: 1 NLQLRQRLVGMARQDALTGLLNRRSLDEALNRHIEKPTGSLAC-LMLDIDHFKRFNDRFG 59 Query: 231 HASGDEALILTARAMQSALSE-GALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIH 289 H +GD + A+ + A S+ G L R GGEEF + + G+ A ++A KL V + Sbjct: 60 HDAGDAVMQYVAQVLSEATSDQGTLFRFGGEEFTVLMPDAGIEDATKLAEKLRHAVERAP 119 Query: 290 IHAR-----PLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDRYVVS 335 R P+T+SIGIA A +VS VL AD AL AK+ G++++V S Sbjct: 120 FTYRGRLLDPVTISIGIATAPGAGTVSSVLERADAALLSAKQTGRNKWVSS 170 >mll4839 [T] COG2199 FOG Mlo Mesorhizobium loti Length = 253 Score = 107 bits (267), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 66/156 (42%), Positives = 94/156 (60%), Gaps = 10/156 (6%) Query: 182 AFKDPLTGIDNRRRFMQQLPIILQAGQPSD-ACFLMIDIDNFKKINDDFGHASGDEALIL 240 A +D +TG+ NR F L + + SD L+ID D+FKKIND FGH +GD+AL+L Sbjct: 89 ASRDDMTGMLNRESFFAALD---GSRRKSDRGALLIIDADHFKKINDSFGHLTGDDALLL 145 Query: 241 TARAMQSALSEG-ALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEV-----RQIHIHARP 294 A A++ + G LGR+GGEEFG L G A++VA ++ +EV R + P Sbjct: 146 IASAIERGVRSGDVLGRIGGEEFGAFLVGATEQEAKRVAERIRREVELIRFRPVDERTIP 205 Query: 295 LTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKD 330 LTVSIG + +VS+++ AAD+ LYQAK G++ Sbjct: 206 LTVSIGGTVCGEDVNVSELMRAADRRLYQAKHRGRN 241 >aq_035_2 [T] COG2199 FOG Aae Aquifex aeolicus Length = 251 Score = 105 bits (263), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 69/180 (38%), Positives = 98/180 (54%), Gaps = 8/180 (4%) Query: 163 TVKRQHVESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACF--LMIDID 220 T+K+ +E+ + + E +A DPLTG+ NRR F + L + F LMIDID Sbjct: 65 TLKKILIETSKEKTLYERMALTDPLTGLYNRRVFTEMAEKELAKAKRYGYNFSILMIDID 124 Query: 221 NFKKINDDFGHASGDEALILTARAMQSALSEGAL-GRMGGEEFGIALSGGGLAHAEQVAA 279 NFKKIND +GH GD L + ++ + L R GGEEF + LS L A + A Sbjct: 125 NFKKINDTYGHDVGDLVLKKISEILKRNVRGADLVARFGGEEFIVMLSNTNLNGAVKKAE 184 Query: 280 KLLQEVRQIHIH-----ARPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDRYVV 334 +L + + Q I +TVSIG++ H S+ +++ ADQALY+AKR GK+R V Sbjct: 185 QLRRMIEQTPIELPNGEKLRVTVSIGVSTYRGHESLEELIKEADQALYEAKRKGKNRVEV 244 >TM0143 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Tma Thermotoga maritima Length = 450 Score = 105 bits (263), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 57/155 (36%), Positives = 90/155 (58%), Gaps = 7/155 (4%) Query: 185 DPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEALILTARA 244 D LTG+ N+R M+ L +L++ + + M+DID+FKKIND FGH GDE L + A Sbjct: 298 DGLTGLFNKRAIMRFLEEVLRSEK--NIAVAMMDIDDFKKINDTFGHPVGDEVLRVVANI 355 Query: 245 MQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVR-----QIHIHARPLTVSI 299 ++ + G +GR GGEEF + G + +++ +R +I + +T+S Sbjct: 356 LRETVKIGKVGRYGGEEFMVVFETGERDAVVKTMDNIMENIRNFDWQKIFGSEKKVTLSG 415 Query: 300 GIARAADHSSVSKVLSAADQALYQAKRAGKDRYVV 334 G+A + SS +++ AD+ LY AKR+GKDRYV+ Sbjct: 416 GVAFSKKESSPVELIEEADKKLYTAKRSGKDRYVI 450 >VC1599 [T] COG2199 FOG Vch Vibrio cholerae Length = 353 Score = 104 bits (260), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 70/227 (30%), Positives = 107/227 (47%), Gaps = 9/227 (3%) Query: 111 MFARTRYYMVAVCGMYLILGRGSFIDAEVVGDE-RWMLLLTLTVLGLGNFVNLTVKRQHV 169 +F R+ V C +I + + G W +LL L +G +V V + Sbjct: 109 IFTSARFAFVTSCLFLIIQSNIIYWQLQQTGAALSWSVLLHLCFAYIGIWVVAHVYEDNR 168 Query: 170 ESLRLRKELEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDF 229 ++ L ++A +DPLTG NR + + C L+ID+D FK IND F Sbjct: 169 R--KIENSLLYLASRDPLTGAHNRLSLTTSFQHFERFSDQTSLCLLVIDLDFFKSINDQF 226 Query: 230 GHASGDEALILTARAMQSALSEGALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIH 289 GH +GD+ LI T R + + L R+GGEEF + L L A +V L V Q H Sbjct: 227 GHDTGDKVLIETTRLFTQVVGDNNLYRIGGEEFCVTLFDQSLEQAGRVCEHLRAIVSQ-H 285 Query: 290 IHA-----RPLTVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDR 331 + A +T+SIG+ ++ +L AD LY+AK+AG+++ Sbjct: 286 LFAFREKRVQVTISIGVCEYQAGDQLNDLLKFADMELYRAKKAGRNQ 332 >DR0267 [T] COG2199 FOG Dra Deinococcus radiodurans Length = 511 Score = 103 bits (258), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 71/221 (32%), Positives = 112/221 (50%), Gaps = 9/221 (4%) Query: 118 YMVAVCGMYLILGRGSFIDAEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKE 177 Y+ + +L+L G E W + L + V+ FV R + + R +E Sbjct: 286 YLAMIVSGFLLLRSGVSPQFPHKQIEIWTVALFVVVMLRQAFVGWESARLNQQLARQAQE 345 Query: 178 LEFIAFKDPLTGIDNRRRFMQQLPIILQAGQPSDACFLMIDIDNFKKINDDFGHASGDEA 237 L +AF D LTG+ NR F +L L +P L +D++NFK +ND GHA+GD+A Sbjct: 346 LHHLAFHDALTGLHNRAAFEDELQRQLHVPRPQPLALLYLDLNNFKPVNDTLGHAAGDQA 405 Query: 238 LILTARAMQSALSEGA-LGRMGGEEFGIALSG-----GGLAHAEQVAAKLLQEVRQIHIH 291 L A+ +Q+AL G + R+GG+EF + L+ A EQ+ A L+ Q+ H Sbjct: 406 LAQVAQRLQAALPAGTFVARLGGDEFAVLLTSIPDEDAAWAAEEQIRAA-LERPMQLGEH 464 Query: 292 ARPLTVSIGIARA-ADHSSVSKVL-SAADQALYQAKRAGKD 330 L+ ++G+ A A + V ++L ADQA+Y+ K + D Sbjct: 465 VVHLSAAVGVTLAPAGEAVVPEILWREADQAMYRVKHSASD 505 >SMc04015 [T] COG2199 FOG Sme Sinorhizobium meliloti Length = 307 Score = 103 bits (256), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 75/208 (36%), Positives = 105/208 (50%), Gaps = 26/208 (12%) Query: 137 AEVVGDERWMLLLTLTVLGLGNFVNLTVKRQHVESLRLRKELEFIAFK-DPLTGIDNRRR 195 E V + WML + V++T R LR ++ A + D LT + NRR Sbjct: 94 TETVDQKGWMLCIA---------VDITDVRAGERKLRQDRDFALRASQVDELTSVPNRRY 144 Query: 196 FMQQLPIILQ--AGQPSD-ACFLMIDIDNFKKINDDFGHASGDEALILTARAMQSALSEG 252 M++L ++ A P C +IDID FK IND +GH GDE L+ AR MQ + Sbjct: 145 TMERLNEFIRNCAENPHMWGCVAIIDIDYFKAINDRYGHHRGDEVLLDFARQMQEFVRRS 204 Query: 253 -ALGRMGGEEFGIALSGGGLAHAEQVAAKLLQEVRQIHIHARPL--------TVSIGIAR 303 GR+GGEEF + L + A + +LL ++R +ARPL T S+G+A Sbjct: 205 DCFGRIGGEEFMLILPDTTVGEANLILDRLLDKIR----NARPLSNIPEFFYTCSVGLAE 260 Query: 304 AADHSSVSKVLSAADQALYQAKRAGKDR 331 + SV + S AD+ALY AKR G+DR Sbjct: 261 YREGDSVGDIYSRADEALYIAKREGRDR 288 >RC0321 [T] COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain Rco Rickettsia conorii Length = 450 Score = 102 bits (254), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 67/174 (38%), Positives = 98/174 (56%), Gaps = 16/174 (9%) Query: 174 LRKELE---FIAFKDPLTGIDNRRRFMQQLP-IILQAGQPSDACFL-MIDIDNFKKINDD 228 LR +LE +A KD LTG+ NRR F L II + + S +L M DIDNFK +ND Sbjct: 277 LRNDLEQSVNLAVKDGLTGLFNRRYFDIHLKQIIEKTNKESIKLYLLMCDIDNFKHVNDT 336 Query: 229 FGHASGDEALILTARAMQSALSEGAL-GRMGGEEFGIALS----GGGLAHAEQVAAKLLQ 283 +GH +GD+ L + +R +++ L L R GGEEF I L+ +A AE++ K+ Sbjct: 337 YGHQAGDKVLTIVSRILKNTLRVTDLIARFGGEEFTILLTDIDISKAIATAERIRVKI-- 394 Query: 284 EVRQIHIHAR--PL--TVSIGIARAADHSSVSKVLSAADQALYQAKRAGKDRYV 333 E HI + PL T+SIG+ + S+ + AD+A+Y+AK GK++ V Sbjct: 395 EYMNFHIEDQIEPLKTTISIGVTKYKKEESIESFIERADKAMYEAKTTGKNKVV 448