BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0134.p (522 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2727 [GEPR] COG0477 Permeases of the major facilitator superf... 688 0.0 PA3137 [GEPR] COG0477 Permeases of the major facilitator superfa... 345 2e-94 mll0994 [GEPR] COG0477 Permeases of the major facilitator superf... 337 5e-92 RC0200 [GEPR] COG0477 Permeases of the major facilitator superfa... 282 2e-75 RP157 [GEPR] COG0477 Permeases of the major facilitator superfam... 280 7e-75 CC3715 [GEPR] COG0477 Permeases of the major facilitator superfa... 277 4e-74 AGl781 [GEPR] COG0477 Permeases of the major facilitator superfa... 271 2e-72 BMEII1119 [GEPR] COG0477 Permeases of the major facilitator supe... 267 4e-71 PA1236 [GEPR] COG0477 Permeases of the major facilitator superfa... 259 1e-68 SMc03167 [GEPR] COG0477 Permeases of the major facilitator super... 259 1e-68 >RSc2727 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 511 Score = 688 bits (1775), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/509 (71%), Positives = 427/509 (83%) Query: 14 ANGEKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAE 73 ANG +ADAAAW AVAAGTLGA+MATLDISIVNS+LPTIQGEIGA+ TEGTWIATAYLVAE Sbjct: 3 ANGSRADAAAWAAVAAGTLGAMMATLDISIVNSALPTIQGEIGATSTEGTWIATAYLVAE 62 Query: 74 IVIIPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPT 133 I+IIP++ WLE+LLGLR LLL A LFT FS+LCG++ TLPMM++GR GQGFTGG LIPT Sbjct: 63 IIIIPLAGWLEKLLGLRNLLLAATGLFTGFSMLCGVAETLPMMVIGRAGQGFTGGVLIPT 122 Query: 134 AMTIIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALI 193 AMTIIA RLPR+QQP+G A+FG+T ILGPV GP++GGW+T ++WHYAFFINLP+ L Sbjct: 123 AMTIIAARLPRAQQPLGTALFGSTVILGPVFGPMLGGWMTTQLNWHYAFFINLPICGVLA 182 Query: 194 TLLLVAIPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATS 253 LLL+ +P+ERP+ L EADW GIAGLALGLGG+TVVLEEG+R QWF+SP IRWLAA S Sbjct: 183 ALLLLGMPHERPRTALLREADWAGIAGLALGLGGMTVVLEEGQRLQWFTSPAIRWLAAVS 242 Query: 254 VLGFILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGY 313 LGF LL GQ RAR PVI+L LLRDRQFG++ +MA+ +ALYGTAYVIPQFL GIAGY Sbjct: 243 ALGFGLLGWGQARARAPVIRLGLLRDRQFGAIAVMAIAASMALYGTAYVIPQFLVGIAGY 302 Query: 314 NSLQSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASAFIETDLSPLSYGG 373 ++LQSGWIVLLSG+PMI++MP PL++R +D+R+AVG G L+LA SA+IET LSPLS G Sbjct: 303 DALQSGWIVLLSGLPMIVLMPMLPLMLRWLDVRLAVGGGLLVLALSAYIETGLSPLSTGN 362 Query: 374 SFVASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQD 433 SFVASQLMRG+GTVL M+FLNQAAIRSVPPSQA DASGLY+ RNLGGS+ALA IA +Q+ Sbjct: 363 SFVASQLMRGLGTVLTMMFLNQAAIRSVPPSQASDASGLYNGLRNLGGSIALACIATLQE 422 Query: 434 QRLWLHSRRLEESLNANSDLVQSSMTAQGHLLGGQDVALQLMGATIQSQALTMTYADLFW 493 QRLWLHSRR+E++L AN+ VQ + Q H LG Q AL M +IQ QALTM YADLFW Sbjct: 423 QRLWLHSRRIEDTLQANAAGVQDYIAGQAHALGSQAAALLSMEQSIQVQALTMAYADLFW 482 Query: 494 MLGVAILCVTPLVLFLRPLPTHAAPVASH 522 +L VAIL VTPLV+FLRPLP HA PVA H Sbjct: 483 LLTVAILLVTPLVVFLRPLPRHAGPVAGH 511 >PA3137 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 499 Score = 345 bits (884), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 192/482 (39%), Positives = 278/482 (57%) Query: 32 LGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVIIPMSAWLERLLGLRV 91 LGA MA LDI I NSSL IQG + A+ EG+WI+T+YLVAEI++IPM+AWL +LL R Sbjct: 6 LGAFMAVLDIQITNSSLKDIQGALAATLEEGSWISTSYLVAEIIMIPMTAWLVQLLSARR 65 Query: 92 LLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMTIIATRLPRSQQPVGN 151 L + + F + S+LC + L MIV R QGFTGGALIP A T+ +LP +P G Sbjct: 66 LAVMISVGFLVSSLLCSFAWNLESMIVFRAMQGFTGGALIPLAFTLALVKLPEHHRPKGM 125 Query: 152 AMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLLLVAIPYERPKFEQLA 211 A+F TA P +GP +GGWLTEN W Y F+IN+P G +I LL + + P +E L Sbjct: 126 ALFAITATFAPSIGPTLGGWLTENFGWEYIFYINVPPGLLMIAGLLYGLEKKAPHWELLK 185 Query: 212 EADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLGFILLAIGQVRARHPV 271 D+ GI L +GLG L V LEEG R+ W S I L + ++ +L I Q+ +P+ Sbjct: 186 STDYAGIVTLGIGLGCLQVFLEEGHRKDWLESQLIVSLGSVALFSLVLFVILQLSRPNPL 245 Query: 272 IQLRLLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSLQSGWIVLLSGVPMIL 331 I L +LR+R FG + ++ +G+ LYG+ YV+P +L+ I GYN++Q G +++ G+P + Sbjct: 246 IDLGILRNRNFGLASISSIGLGMGLYGSIYVLPLYLAQIQGYNAMQIGEVIMWMGIPQLF 305 Query: 332 MMPFTPLLMRLVDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFVASQLMRGVGTVLAML 391 ++P P LM+LV R+ GF L ++F L+P G F QL+R +G + M+ Sbjct: 306 LIPLVPKLMKLVSPRLLCAAGFGLFGLASFFSGVLNPDFAGPQFNQIQLLRALGQPMIMV 365 Query: 392 FLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRLWLHSRRLEESLNANS 451 ++ A + P AG AS L++ RNLGG++ +A +A + D R ++ L E+L + Sbjct: 366 TISLIATAYLQPQDAGSASSLFNILRNLGGAIGIALLATLLDSRAKVYFDYLREALVPTN 425 Query: 452 DLVQSSMTAQGHLLGGQDVALQLMGATIQSQALTMTYADLFWMLGVAILCVTPLVLFLRP 511 V + LG Q AL + QA+ M Y D F ++G+ + VL R Sbjct: 426 PQVDERLAQLAAQLGSQQAALGKLSEITHQQAMIMAYNDAFHVIGMVLAVSMLAVLLTRS 485 Query: 512 LP 513 LP Sbjct: 486 LP 487 >mll0994 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 537 Score = 337 bits (863), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 198/532 (37%), Positives = 301/532 (56%), Gaps = 17/532 (3%) Query: 4 APAKP-MAAAGANGEKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEG 62 APA+P G+ G A W+AV +LGA MA L+I IVN+SL IQG IGA +G Sbjct: 10 APARPARNETGSAGTAASPRVWVAVVGSSLGAFMAVLNIQIVNASLADIQGAIGAGIDDG 69 Query: 63 TWIATAYLVAEIVIIPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVG 122 WI+TAYL+AEIV+IP++ WL ++ LR L+ A LF FSV C + L MIV R Sbjct: 70 GWISTAYLIAEIVVIPLTGWLSQVFSLRNYLIANAVLFLAFSVACAFAANLGQMIVLRAI 129 Query: 123 QGFTGGALIPTAMTIIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAF 182 QGFTGG LIP A TI+ T LP+++QP+G A+F +A P +GP +GG+LTEN W Y F Sbjct: 130 QGFTGGVLIPMAFTIVITLLPKARQPIGLALFAMSATFAPAIGPTIGGYLTENWGWQYIF 189 Query: 183 FINLPVGAALITLLLVAIPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFS 242 ++N+ GA ++ +L ++ + + L E DW GIA +A+GL L VLEEG + WF Sbjct: 190 YVNIVPGALMVGMLWFSLDRQPMRLALLGEGDWPGIATMAIGLAALQTVLEEGNKNDWFG 249 Query: 243 SPDIRWLAATSVLGFILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTAYV 302 S + LA + + L ++ + HP++ LRLL R FG ++ ++G ALYG+ ++ Sbjct: 250 SLFVLRLAIVAAVSLSLFVWIELTSSHPLLNLRLLLRRNFGFGILANFMLGTALYGSVFI 309 Query: 303 IPQFLSGIAGYNSLQSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASAFI 362 +P +L+ I GYN+ Q G ++ +G+P +L++P P LM+ D+R+ + TGF L AAS F+ Sbjct: 310 LPVYLARIQGYNAEQIGLVLAWTGLPQLLLIPLVPYLMQRFDVRLVIVTGFALFAASNFM 369 Query: 363 ETDLSPLSYGGSFVASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGS 422 ++ ++R +G L L+ A+ + AG AS L++ RNLGG+ Sbjct: 370 NVHMTAGYASDQLFWPNIVRAIGQALVFAPLSAIAVSGIEQENAGSASSLFNMIRNLGGA 429 Query: 423 LALAAIAVIQDQRLWLHSRRLEESLNANSDLVQS----------SMTAQGHLLGGQD--V 470 + +A + +R HS L +S++ + +S S H+L Q + Sbjct: 430 VGIALLQTFLTKRQQYHSNVLVQSISLFEEATRSRIAKLTAYFLSHGVSDHVLAAQKGVI 489 Query: 471 ALQLMGATIQSQALTMTYADLFWMLGVAILCVTPLVLFLRPLPTHAAPVASH 522 A+ L ++ QA M ++D F++LGVA++ L L+ P H +H Sbjct: 490 AIAL---RVRQQAFIMAFSDTFFLLGVALVIALAATLLLKK-PGHIEAGGAH 537 >RC0200 [GEPR] COG0477 Permeases of the major facilitator superfamily Rco Rickettsia conorii Length = 519 Score = 282 bits (721), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 166/485 (34%), Positives = 275/485 (56%), Gaps = 10/485 (2%) Query: 32 LGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVIIPMSAWLERLLGLRV 91 +G M+ LDI IV SSL I + AS E +W+ T+YL+AE++IIP++ +L RLL R+ Sbjct: 24 VGMFMSVLDIQIVASSLSVIAAGLAASSDELSWVQTSYLIAEVIIIPITGFLARLLTTRI 83 Query: 92 LLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMTIIATRLPRSQQPVGN 151 AA FT+ S+LC L+T + MI+ R QGF GGA+IPT + + P SQ+P+ Sbjct: 84 SYFIAALGFTVMSILCSLATNIESMIIFRALQGFFGGAMIPTVFSTVFILFPASQRPIVT 143 Query: 152 AMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLLLVAIPYERPKFEQLA 211 + G + P LGP +GG++TE +SWH+ F +N+ G + T++ + +++P ++ L Sbjct: 144 ILIGLVVTVAPTLGPTLGGYITEILSWHFMFLLNVIPGIFVCTVVFLYGDFDKPNYKLLK 203 Query: 212 EADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLGFILLAIGQVRARHPV 271 D+ GI +AL LG L VLEEG ++ W I +L+ T VLGFILL I ++ +P+ Sbjct: 204 NFDFLGILLMALTLGLLQYVLEEGNKKGWLEDNLILFLSITVVLGFILLIIRELTCINPI 263 Query: 272 IQLR--LLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSLQSGWIVLLSGVPM 329 + L+ L +D FG + + ++G+ LYGT Y++P FL IAGY++LQ G ++++G Sbjct: 264 LDLKTFLYKDFTFGC--LYSFVMGIGLYGTVYILPLFLFTIAGYDTLQIGATMMVTGGAQ 321 Query: 330 ILMMPFTPLLMRL-VDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFVASQLMRGVGTVL 388 L P ++ L VD+R+ + G A + + L+P S +FV Q +RG+ + Sbjct: 322 FLSAPLAGRMLGLGVDLRLMLIIGLGGFALGCHLNSFLTPDSKFAAFVLPQFVRGLSLMF 381 Query: 389 AMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRLWLHSRRLEESLN 448 + N A+ ++P + G+ASGLY+ RNLGG++ LA I+ I + L E+++ Sbjct: 382 CFIPTNNIALGNMPKERVGNASGLYNLTRNLGGAVGLAIISTILTNDTKTFMQYLSENIS 441 Query: 449 ANSDLVQSSMTAQGHLLGG-----QDVALQLMGATIQSQALTMTYADLFWMLGVAILCVT 503 + S + + + LL G + + L+ + A + ++F M+G+ + + Sbjct: 442 STSIMALEQLDSYTELLSGKVLNPEKASYLLLANKLNHDAFVIAINNIFNMIGLLFVFIM 501 Query: 504 PLVLF 508 L+ F Sbjct: 502 LLIPF 506 >RP157 [GEPR] COG0477 Permeases of the major facilitator superfamily Rpr Rickettsia prowazekii Length = 519 Score = 280 bits (715), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 163/492 (33%), Positives = 275/492 (55%), Gaps = 10/492 (2%) Query: 25 LAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVIIPMSAWLE 84 LA +G M+ LDI IV SSL I + AS E +W+ T+YL+AE++IIP++ +L Sbjct: 17 LAFFGMIVGMFMSVLDIQIVASSLSVIAAGLAASSDELSWVQTSYLIAEVIIIPITGFLA 76 Query: 85 RLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMTIIATRLPR 144 RLL R+ AA FT+ SVLC L+ + MI+ R QGF GGA+IP + + P Sbjct: 77 RLLSTRICYFIAALGFTIMSVLCSLANNIESMIIFRALQGFFGGAMIPLVFSTVYIIFPA 136 Query: 145 SQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLLLVAIPYER 204 SQ+P + G + P LGP +GG++TE +SWH+ F +N+ G + T++ + + +++ Sbjct: 137 SQRPTVTILIGLVVTVAPTLGPTLGGYITEILSWHFMFLLNVIPGIFVCTVVFLYVNFDK 196 Query: 205 PKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLGFILLAIGQ 264 P ++ L D+ GI ++L LG L VLEEG +E W I +L+ T LGFILL I + Sbjct: 197 PNYQLLKNFDFLGILLMSLTLGLLQYVLEEGNKEGWLDDNLILFLSITVALGFILLIIRE 256 Query: 265 VRARHPVIQLR--LLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSLQSGWIV 322 + +P++ L+ L +D FG + + ++G+ LYG Y++P FL IA Y++LQ G + Sbjct: 257 LTFINPILDLKTFLYKDFTFGCI--YSFVMGIGLYGAVYILPLFLFTIAEYDTLQIGATM 314 Query: 323 LLSGVPMILMMPFTPLLMRL-VDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFVASQLM 381 +++GV L P ++ L +D+R+ + G A + + L+P S +F+ Q + Sbjct: 315 MVTGVAQFLSAPLAGRMLGLGIDLRMMLTIGLGGFALGCHLNSCLTPDSKFAAFILPQFV 374 Query: 382 RGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRLWLHSR 441 RG + + N A+ ++P + G+ASGLY+ RNLGG++ LA I+ I + + Sbjct: 375 RGFSLMFCFIPTNNIALGNMPKEKVGNASGLYNLTRNLGGAVGLAIISTILSNDTKIFMQ 434 Query: 442 RLEESLNANSDLVQSSMTAQGHLLGGQDV-----ALQLMGATIQSQALTMTYADLFWMLG 496 L E+++ S + + + + LL G+ + + L+ + + A + ++F M+G Sbjct: 435 YLSENISYTSIIALTRLDSYTELLSGKILNPEQGSYLLLANKLNNDAFVIAINNIFNMIG 494 Query: 497 VAILCVTPLVLF 508 + + + L+ F Sbjct: 495 LLFVFIMLLIPF 506 >CC3715 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 533 Score = 277 bits (709), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 188/523 (35%), Positives = 282/523 (53%), Gaps = 15/523 (2%) Query: 3 SAPAKPMAAAGANGEKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEG 62 SAPA P A A + K +L A +G MA LDI IV +SLP IQ +GAS + Sbjct: 12 SAPATPGATAPVDWTKL----FLGFGAMVIGQFMAILDIQIVAASLPQIQAGVGASTDQV 67 Query: 63 TWIATAYLVAEIVIIPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVG 122 +WI TAYL+ E+V+IP+S +L RL G + L L + + F + S+L GLST++ MMI+ R Sbjct: 68 SWIQTAYLIPEVVMIPLSGYLSRLWGTQKLYLASCAGFIVMSILTGLSTSIDMMIITRAL 127 Query: 123 QGFTGGALIPTAMTIIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAF 182 QGF GGA+IPT + T P ++ + + G L P +GP +GG LTE +SW + F Sbjct: 128 QGFIGGAMIPTVFAVAFTAFPPERRVTASVIMGLIVTLAPTVGPTLGGHLTEWLSWRWLF 187 Query: 183 FINLPVGAALITLLLVAIPYERPKFE-QLAEA-DWFGIAGLALGLGGLTVVLEEGEREQW 240 FIN+P G LI L VA + K + LA+ DWFG+A +A+ L + VLEEG +E W Sbjct: 188 FINVPTG--LIVLFGVARWGDFDKGDPSLAKGFDWFGLAVMAVFLMSMQYVLEEGAKEDW 245 Query: 241 FSSPDIRWLAATSVLGFILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTA 300 S I WL +V G ++ Q+ R+P+++LR +R F V+M + G +L+G Sbjct: 246 LSDSLILWLTVVAVFGGVVFVWRQLTYRNPIVELRAFANRNFTVGVLMTAVSGASLFGGT 305 Query: 301 YVIPQFLSGIAGYNSLQSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASA 360 +++PQFL + Y++ + G +++SG+ M L P L+R D R+ + GFLL Sbjct: 306 FLLPQFLGRVRHYSASEVGTTMVISGLSMFLTGPIAGRLVRKTDPRLPMCVGFLLAGFGM 365 Query: 361 FIETDLSPLSYGGSFVASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLG 420 ++ ++ F Q RGVG ++AM+ Q + ++PP +ASGL + +RN G Sbjct: 366 YMAHGVTKDWGFWEFAGVQACRGVGVMIAMIATQQITMSTLPPHMVKNASGLVNLSRNTG 425 Query: 421 GSLALAAIAVIQDQRLWLHSRRLEESLNANSDLVQ--SSMTAQGHLLGGQD---VALQLM 475 G++ LA +A Q+ L+ L + S + +T + LG D A + + Sbjct: 426 GAIGLALLATSITQQTALYYDDLTSKVTQGSAAAGMIAGLTERMMQLGVADPAGAARKAV 485 Query: 476 GATIQSQALTMTYADLFWMLGVAILCVTPLVLFLRPLPTHAAP 518 G +Q QA M + D F +L AI C + L P AP Sbjct: 486 GGMMQQQATVMAFGDSFTLL--AIGCFIAAAVSLLAAPVKNAP 526 >AGl781 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 527 Score = 271 bits (694), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 156/481 (32%), Positives = 256/481 (53%), Gaps = 5/481 (1%) Query: 20 DAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVIIPM 79 D +A A G M+ LDI IV++SL IQ +GA E W+ T+YL+AE+++IP+ Sbjct: 20 DRRRLIAFFAMVFGMFMSILDIQIVSASLAEIQAGLGAGSDEIAWVQTSYLIAEVIMIPL 79 Query: 80 SAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMTIIA 139 S L R+L RVL T A+ FTL S LC +T + MIV R QGF GG +IP+ Sbjct: 80 SGTLARILSTRVLFATCAAGFTLSSALCATATNIDQMIVYRAIQGFIGGGMIPSVFAAAF 139 Query: 140 TRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLLLVA 199 T P S++ V + + G A L P +GP +GG+L+ SWH+ F +N+ G + L Sbjct: 140 TIFPPSKRSVVSPIIGLVATLAPTIGPTVGGYLSNAFSWHWLFLVNIIPGIIVTILTWSL 199 Query: 200 IPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLGFIL 259 I +++P+ + DW+G+ +A+ LG L VLEEG + WF+ I + V+G ++ Sbjct: 200 IDFDKPETSLWKKFDWWGLISMAVFLGSLEYVLEEGNNKDWFNDEHIVIGSVAMVIGAVV 259 Query: 260 LAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSLQSG 319 + PV+ +R DR F + + ++G+ LYG Y+ P +L + GY++L G Sbjct: 260 FFWRAFKVDFPVVDIRAFADRNFSIGSLFSFVMGIGLYGLTYLYPLYLGRVRGYDALMIG 319 Query: 320 WIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFVASQ 379 + +SG+ M P + +D R+ + GF+ +I T ++ + Q Sbjct: 320 ETMFVSGLAMFFTAPIAGKVSTKLDPRVMMAIGFISFGCGTWIMTYVTTDWDFYELLIPQ 379 Query: 380 LMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRLWLH 439 ++RG G ++ M+ +N A+ ++PP++ +ASGL++ RNLGG++ LA I + QR H Sbjct: 380 ILRGFGLMMCMVPINNIALGTLPPARIRNASGLFNLTRNLGGAVGLAVINTLLSQRTDDH 439 Query: 440 SRRLEESLNANSD-----LVQSSMTAQGHLLGGQDVALQLMGATIQSQALTMTYADLFWM 494 RL E ++ ++ L + L G VA++ + + QA + +AD+F+ Sbjct: 440 YVRLAEHVSYSNPQALEWLNNVGANYDSYGLDGASVAIKKLVGMVSQQAWMLAFADVFFA 499 Query: 495 L 495 L Sbjct: 500 L 500 >BMEII1119 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 525 Score = 267 bits (683), Expect = 4e-71, Method: Compositional matrix adjust. Identities = 165/512 (32%), Positives = 268/512 (52%), Gaps = 10/512 (1%) Query: 17 EKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVI 76 ++ D + A G MA LDI IV++SL IQ +GAS E +W+ +YL+AE+++ Sbjct: 18 DRIDPKKTIGFMAMVFGMFMAILDIQIVSASLSEIQAGLGASTDEISWVQISYLIAEVIM 77 Query: 77 IPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMT 136 IP+S +L RLL RVL +A+ FTL S+LC +T + MIV R QGF GG +IP+ Sbjct: 78 IPLSGFLGRLLSTRVLFTISATGFTLASMLCATATNIEQMIVYRAIQGFIGGGMIPSVFA 137 Query: 137 IIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLL 196 T P S++ + + M G A L P +GG+L+ SWH+ F +N+ G + Sbjct: 138 AAFTIFPPSKRSIVSPMIGLVA----TLAPTIGGYLSHAFSWHWLFLVNVGPGILVTIAA 193 Query: 197 LVAIPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLG 256 I ++ L + DW+G+ G+A LG L VLEEG R W I ++ +G Sbjct: 194 WNLIDFDEGDLSLLDKFDWWGLFGMAAFLGSLEYVLEEGPRNDWLQDHTIFIMSIILTVG 253 Query: 257 FILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSL 316 I+ A P++ R R+ F + + ++GV LYG Y+ P +LS I GY++L Sbjct: 254 AIVFFYRVFTAEQPIVDFRAFRNMNFAFGSLFSFVMGVGLYGLTYLYPLYLSMIRGYDAL 313 Query: 317 QSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFV 376 G + +SG+ M P L +D R+ + GF+ A ++ T L+ + Sbjct: 314 MIGEALFVSGLAMFFTAPVAGFLSNRMDPRLMMMIGFVGFAIGTWLVTGLTADWDFNELL 373 Query: 377 ASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRL 436 Q++RG +L M+ +N A+ ++PPS +ASGL++ RNLGG++ LA I I +R Sbjct: 374 MPQILRGCSLMLCMVPINNLALGTLPPSLMKNASGLFNLTRNLGGAVGLAVINTILTRRG 433 Query: 437 WLHSRRLEESL---NANSDLVQSSMTAQGHLLG--GQDVALQLMGATIQSQALTMTYADL 491 +H RL E + NA ++ + +++TA+ + G G +A+ + ++ QA +++ D+ Sbjct: 434 DMHYARLAEHVRNGNAEAENMIANLTAKYNAAGMDGASIAIAKLSGMVRQQATLLSFIDV 493 Query: 492 FWMLGVAILCVTPLVLFLR-PLPTHAAPVASH 522 F++L + + + LR P P H Sbjct: 494 FFILTMMFCSLAICAMLLRKPSPAAGGGGGGH 525 >PA1236 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 503 Score = 259 bits (662), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 172/481 (35%), Positives = 270/481 (56%), Gaps = 4/481 (0%) Query: 17 EKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVI 76 +K AW+AV G G MA +++ + +++LP I+G +GA+ EG+WI+TAYLVAEI + Sbjct: 5 DKVSLRAWVAVTGGLFGCFMAGMNVHVTSAALPEIEGALGATFEEGSWISTAYLVAEISM 64 Query: 77 IPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMT 136 IP++AWL + LR ++L + +F L S+ C L+ L +I+ RV QG +G LIP +M Sbjct: 65 IPLTAWLVEVFSLRRVMLLGSLVFLLSSLSCALAPNLSTLILIRVIQGASGAVLIPLSMQ 124 Query: 137 IIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLL 196 +I T LP S+ P+G A+F + + GP +GGWL + SW + F + L G AL+ + Sbjct: 125 LILTELPSSRIPLGMALFSLSNSVAQAAGPSIGGWLADAYSWRWIFLLQLLPGIALLAAV 184 Query: 197 LVAIPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLG 256 +I E+L +ADW GI + GLG L +VLEEG R WF S IR A +VL Sbjct: 185 AWSIRPRDGDRERLRQADWLGIGAMVAGLGALQIVLEEGGRRDWFESGFIRTFAVLAVLA 244 Query: 257 FILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSL 316 +L Q+ P I LRLL FG + + G A +G +++P +LS + G+N+ Sbjct: 245 LLLFVQRQLWGARPFINLRLLGSYNFGVSSLAMAVFGAATFGLVFLVPNYLSQLQGFNAR 304 Query: 317 QSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFV 376 Q G ++L G+ +L+ P P LMR ++ ++ V GF ++A ++ L+ + + Sbjct: 305 QIGDSLILYGLVQLLLAPLLPRLMRWLNPKLLVAGGFAIMALGCWMGAHLNADAGRNVII 364 Query: 377 ASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRL 436 S ++RG+G L M+ L+ A++ + +QAG AS L S RNLGG++ A + + R Sbjct: 365 PSIVVRGIGQPLIMVALSVLAVKGLDKAQAGSASALISMLRNLGGAIGTALLTQLVSLRE 424 Query: 437 WLHSRRLEESLNANSDLVQSSMTAQGHL---LGGQDVALQLMGATIQSQALTMTYADLFW 493 HS R+ E+L +Q + G + L Q AL L+ ++ QA M Y+D F+ Sbjct: 425 RFHSERIGETLTIFDGALQQRLGG-GQVRIQLPEQQQALALLDHGVRQQAYLMAYSDAFY 483 Query: 494 M 494 + Sbjct: 484 L 484 >SMc03167 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 529 Score = 259 bits (662), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 167/498 (33%), Positives = 264/498 (53%), Gaps = 5/498 (1%) Query: 17 EKADAAAWLAVAAGTLGALMATLDISIVNSSLPTIQGEIGASGTEGTWIATAYLVAEIVI 76 E D +A A +G MA LDI IV++SL IQ + A E W+ TAYL+AE+++ Sbjct: 19 EHMDPRRLIAFFAMVVGMFMAILDIQIVSASLAEIQAGLSAGSDEIGWVQTAYLIAEVIM 78 Query: 77 IPMSAWLERLLGLRVLLLTAASLFTLFSVLCGLSTTLPMMIVGRVGQGFTGGALIPTAMT 136 IP+S L R++ RVL AA+ FT S L +T + MIV R QGF GG +IP+ Sbjct: 79 IPLSGTLARIVSTRVLFSVAAAGFTAASALAATATNIEQMIVYRAIQGFIGGGMIPSVFA 138 Query: 137 IIATRLPRSQQPVGNAMFGATAILGPVLGPVMGGWLTENVSWHYAFFINLPVGAALITLL 196 T P S++ V + + G A L P +GP +GG+L+ SWH+ F IN+ G + T+ Sbjct: 139 AAFTIFPPSKRNVVSPIIGLIATLAPTIGPTVGGYLSHAFSWHWLFLINVIPGIIVATVT 198 Query: 197 LVAIPYERPKFEQLAEADWFGIAGLALGLGGLTVVLEEGEREQWFSSPDIRWLAATSVLG 256 + I +++P+ + + DW+G+ +A+ LG L VLEEG WF+ I A + + Sbjct: 199 WIFIDFDKPELGLIKKFDWWGLLSMAIFLGSLEYVLEEGNANDWFNDEHIVMGAVATTVA 258 Query: 257 FILLAIGQVRARHPVIQLRLLRDRQFGSVVMMAMIVGVALYGTAYVIPQFLSGIAGYNSL 316 ++ + PV+ L+ +R F + + ++G+ LYG Y+ P +L I GY+SL Sbjct: 259 AVVFFYRAFKVDFPVVDLKAFANRNFTFGSLFSFVMGIGLYGLTYLYPLYLGRIRGYDSL 318 Query: 317 QSGWIVLLSGVPMILMMPFTPLLMRLVDIRIAVGTGFLLLAASAFIETDLSPLSYGGSFV 376 G + +SG+ M L P L +D R + GF AA ++ + ++ + Sbjct: 319 MIGETMFVSGLAMFLTAPVAGFLAGRMDARAMMTIGFAGFAAGTWLMSQMTADWDFWELL 378 Query: 377 ASQLMRGVGTVLAMLFLNQAAIRSVPPSQAGDASGLYSAARNLGGSLALAAIAVIQDQRL 436 Q++RG +L M+ +N A+ ++PP++ +ASGLY+ RNLGG++ LA I I QR Sbjct: 379 VPQILRGCSLMLCMVPINNIALGTLPPARIRNASGLYNLTRNLGGAVGLAVINTILTQRQ 438 Query: 437 WLHSRRLEESLNANSDLVQSSM-----TAQGHLLGGQDVALQLMGATIQSQALTMTYADL 491 H RL E + + + M T H L G A++ + A +Q QA+ M++ D+ Sbjct: 439 DFHYARLAEHVEWGNPVAVERMRNIASTFTAHGLDGTTAAVKQLAAMVQQQAVIMSFIDV 498 Query: 492 FWMLGVAILCVTPLVLFL 509 F +L V L + VL + Sbjct: 499 FVLLTVLFLSMIAGVLMI 516