BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0108.p (336 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC0896 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 161 2e-39 CC1117 Non COG 158 2e-38 AGc3765 [K] COG0583 Transcriptional regulator Atu Agrobacterium ... 157 3e-38 mlr1973 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 150 3e-36 YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 150 3e-36 gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 150 4e-36 ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 150 4e-36 ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 150 4e-36 STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 150 5e-36 mll6971 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium ... 145 2e-34 >VC0896 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 306 Score = 161 bits (407), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 99/301 (32%), Positives = 153/301 (50%), Gaps = 5/301 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL +LKVFEAA R S T AA ELF+T +AVS QIK+LEE+ LF R++R + Sbjct: 1 MSRRLPPLNSLKVFEAAARHLSFTRAAEELFVTQAAVSHQIKALEEFLGLKLFRRRNRSL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 TE S++ ++K +A A ++L + + + PS A++WL+PRL+ F Sbjct: 61 LLTEEGQSYFLDIKDIFSSLAEATDKLLERSEKGALTISLPPSFAIQWLVPRLADFNQQE 120 Query: 145 PRIEVRVTTT-MSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPH-FLETH 202 P I+VR+ M E + D DV I+ G + + +PL SP L Sbjct: 121 PDIDVRIKAVDMDE--GSLTDDVDVAIYYGRGSWPGLRADKLYQEFLIPLCSPALLLGNK 178 Query: 203 PIRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVG 262 P+ D L+H +SR W Q+ + G+ G ++ HS + LQAAA QGV Sbjct: 179 PMEKLSDLAYHTLLHDTSRK-DWKQFAKENGLDNVNVNHGPIFSHSTMVLQAAAHGQGVA 237 Query: 263 MGTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWLKQMGQASSF 322 +G L ++ AGRL+ F E+++ ++++C + TF W+ + ++ Sbjct: 238 LGNNVLAQPEIDAGRLIAPFDEVLMTNNAFYVVCHEKQADMGRIATFRDWMLKKARSEQV 297 Query: 323 D 323 D Sbjct: 298 D 298 >CC1117 Non COG Length = 340 Score = 158 bits (400), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 101/291 (34%), Positives = 150/291 (51%), Gaps = 6/291 (2%) Query: 29 LPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGVEPTE 88 LPPL AL+ FEAA R + + AA EL +T AVSQQI++LE+Y LF R +G+ T+ Sbjct: 32 LPPLNALRAFEAAARHLNFSRAADELSVTPGAVSQQIQNLEDYVGAALFKRTPKGLLLTD 91 Query: 89 AALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDNPRIE 148 AA + ++ + DR+A AA L A R + L AAPS A +WL+PRL +F+ +P+++ Sbjct: 92 AAQTALPALREAFDRLAEAASLLTAAVDGRRLTLTAAPSFAAKWLVPRLGKFEQAHPQVD 151 Query: 149 VRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETHPIRVPR 208 V ++ M E + D+ I G E +R L + VP+ASP LE + + P Sbjct: 152 VWLSAGM-EVVDFATGEVDMAIRYGSGRYPGLEVIRLLHETVVPVASPELLEQNALERPE 210 Query: 209 DFVEVPLIHLSSRSA-----AWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 D L+H S A W+ WL+ G+ G + S L ++AAA +G+ + Sbjct: 211 DLQHHILLHDGSPDADDSCPDWAMWLAARGIRGVDGARGPRFNQSSLVIEAAANGRGIAL 270 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWLK 314 L DL +GRLV F Y+++ P +K F+ WLK Sbjct: 271 AKRTLAQADLDSGRLVIPFEASTAVDFAYYVVHPKAKGRLPQVKAFVNWLK 321 >AGc3765 [K] COG0583 Transcriptional regulator Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 300 Score = 157 bits (397), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 98/298 (32%), Positives = 155/298 (52%), Gaps = 5/298 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M + LP LK L+ FEAA R RS+TLA++EL +T AVS QI+ LE LF R+ R + Sbjct: 1 MATELPSLKGLQAFEAAARYRSVTLASNELNVTPGAVSLQIRELEARLGVQLFFRKPRSI 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 + T +Y ++ + + A +L + V+ L P+ A++WL+PRL FQ + Sbjct: 61 QLTREGERYYGALRTAFRMMREATAELTARSEITVLTLSCTPTFAVQWLMPRLPSFQQQH 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETH-P 203 P ++VR++ T + + +D D+ + G E +RF+DD ++P+ +P LE + P Sbjct: 121 PHVDVRISVT-NRLVDFSRDDVDLAVRHGFGRYEGLESIRFIDDSTLPVCAPQLLEKYGP 179 Query: 204 IRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 +R D VPL+H +R+ W +WL AG + GTV+ S +L AA G+ + Sbjct: 180 LREAGDLKSVPLLHDENRN-EWRRWLEAAGASEVDASGGTVFIDSNGALDAAKAGHGIAL 238 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWLKQMGQASS 321 +LV +L G L+ F + Y ++ NP L T I W+ + QA S Sbjct: 239 TRRSLVSRELVEGALIAPFGTDMASTLAYFLVYPRRMLDNPDLVTLIDWM--LSQAGS 294 >mlr1973 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 303 Score = 150 bits (380), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 101/292 (34%), Positives = 152/292 (52%), Gaps = 7/292 (2%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 MP LPPL AL F+AA R S + AA EL +TH AVS+ I+++E+ LF R +R V Sbjct: 1 MPRRLPPLTALPAFDAAARHLSFSRAADELNLTHGAVSRAIRNIEDRLGIQLFDRGTRSV 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 T ++ EV +LD+IA A +R++ + + A RWL+PRL +F N Sbjct: 61 RLTAVGAAYAVEVGKALDQIAAATIAATPDRSTRILNVSTSDGFAGRWLVPRLHRFHRAN 120 Query: 145 PRIEVRVTTT--MSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLET- 201 I+VR+ T+ ++++ V D D+ I +G D+ P+ SP L+ Sbjct: 121 ADIDVRLATSGVLADF---VSDGIDIAIRYGKGGYTGVTAEFLADEEVFPVCSPELLQGE 177 Query: 202 HPIRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGV 261 HP+R+P D LIH + R W+ WL +AGV G ++ + +++AA +GV Sbjct: 178 HPLRLPGDLRHHKLIHDAFR-IDWATWLQQAGVDGIDPKRGVRFDSATFAVEAAVHGEGV 236 Query: 262 GMGTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWL 313 +G ALV DLAAGRLVR F + Y+++ GA ++ F WL Sbjct: 237 LLGRSALVSADLAAGRLVRPFDLALKSAASYYLVYPDGALRQKKIRAFRDWL 288 >YPO1029 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 305 Score = 150 bits (380), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 92/290 (31%), Positives = 145/290 (50%), Gaps = 3/290 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL AL+ F+AA R S T AA ELF+T +AVS QIKSLE++ LF R++R + Sbjct: 1 MSKRLPPLNALRAFDAAARHLSFTKAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 TE S+Y ++K I A +L + + PS A++WL+PRLS F Sbjct: 61 LLTEEGQSYYLDIKEIFTSINEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSGFNAAY 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLE-THP 203 P I+VR+ E + + D DV I+ SG R + +P+ +P L + Sbjct: 121 PGIDVRIQAVDREE-DKLADDVDVAIFYGRGNWSGLRTERLYAEFLLPVCAPSLLTGENG 179 Query: 204 IRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 ++VP D L+H +SR W + + GV G ++ HS + +QAA QG+ + Sbjct: 180 LKVPSDLANHTLLHDTSRR-DWLAYTRQLGVPQINVQQGPIFSHSAMVVQAAVHGQGIAL 238 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWL 313 + ++ AGRLV F ++++ ++++C + F W+ Sbjct: 239 VNNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >gcvA [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 305 Score = 150 bits (379), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 90/290 (31%), Positives = 145/290 (50%), Gaps = 3/290 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL AL+VF+AA R S T AA ELF+T +AVS QIKSLE++ LF R++R + Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 TE S++ ++K ++ A +L + + PS A+ WL+PRLS F Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAY 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETH-P 203 P I+VR+ + + + D DV I+ G + + +P+ SP L P Sbjct: 121 PGIDVRIQAVDRQE-DKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKP 179 Query: 204 IRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 ++ P D + L+H +SR W + + G+ G ++ HS + LQAA QGV + Sbjct: 180 LKTPEDLAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVAL 238 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWL 313 + ++ AGRLV F ++++ ++++C + F W+ Sbjct: 239 ANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >ZgcvA [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 305 Score = 150 bits (379), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 90/290 (31%), Positives = 145/290 (50%), Gaps = 3/290 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL AL+VF+AA R S T AA ELF+T +AVS QIKSLE++ LF R++R + Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 TE S++ ++K ++ A +L + + PS A+ WL+PRLS F Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAY 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETH-P 203 P I+VR+ + + + D DV I+ G + + +P+ SP L P Sbjct: 121 PGIDVRIQAVDRQE-DKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKP 179 Query: 204 IRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 ++ P D + L+H +SR W + + G+ G ++ HS + LQAA QGV + Sbjct: 180 LKTPEDLAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVAL 238 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWL 313 + ++ AGRLV F ++++ ++++C + F W+ Sbjct: 239 ANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >ECs3668 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 305 Score = 150 bits (379), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 90/290 (31%), Positives = 145/290 (50%), Gaps = 3/290 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL AL+VF+AA R S T AA ELF+T +AVS QIKSLE++ LF R++R + Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 TE S++ ++K ++ A +L + + PS A+ WL+PRLS F Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLPSFAIHWLVPRLSSFNSAY 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETH-P 203 P I+VR+ + + + D DV I+ G + + +P+ SP L P Sbjct: 121 PGIDVRIQAVDRQE-DKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKP 179 Query: 204 IRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 ++ P D + L+H +SR W + + G+ G ++ HS + LQAA QGV + Sbjct: 180 LKTPEDLAKHTLLHDASRR-DWQTYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGVAL 238 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWL 313 + ++ AGRLV F ++++ ++++C + F W+ Sbjct: 239 ANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >STM2982 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 305 Score = 150 bits (378), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 89/290 (30%), Positives = 146/290 (50%), Gaps = 3/290 (1%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL AL+VF+AA R S T AA ELF+T +AVS QIKSLE++ LF R++R + Sbjct: 1 MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSLEDFLGLKLFRRRNRSL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 TE S++ ++K ++ A +L + + PS A++WL+PRLS F Sbjct: 61 LLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLPPSFAIQWLVPRLSSFNSAY 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETH-P 203 P I+VR+ + + + D DV I+ G + + +P+ SP L P Sbjct: 121 PGIDVRIQAVDRQE-DKLADDVDVAIFYGRGNWPGLRVEKLYAEYLLPVCSPLLLTGEKP 179 Query: 204 IRVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGM 263 ++ P D + L+H +SR W + + G+ G ++ HS + LQAA QG+ + Sbjct: 180 LKTPEDLAKHTLLHDASRR-DWQAYTRQLGLNHINVQQGPIFSHSAMVLQAAIHGQGIAL 238 Query: 264 GTLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWL 313 + ++ AGRLV F ++++ ++++C + F W+ Sbjct: 239 ANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQAELGKIAAFRQWI 288 >mll6971 [K] COG0583 Transcriptional regulator Mlo Mesorhizobium loti Length = 303 Score = 145 bits (365), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 90/296 (30%), Positives = 148/296 (50%), Gaps = 1/296 (0%) Query: 25 MPSSLPPLKALKVFEAAVRTRSLTLAAHELFITHSAVSQQIKSLEEYFEQPLFLRQSRGV 84 M LPPL L+ FEA+ RT S T AA EL IT +AVS+ +KSLE + LF+R+ RG+ Sbjct: 1 MNRYLPPLTWLRAFEASARTLSFTHAASELHITQAAVSKHVKSLEHHLHHVLFIRRPRGL 60 Query: 85 EPTEAALSFYAEVKASLDRIALAAEQLALAGKSRVVRLIAAPSVAMRWLIPRLSQFQIDN 144 E T++ ++ +V+ +++R+A+ ++ ++ + + A S A+ WL RL ++ Sbjct: 61 ELTKSGAAYLPKVQDAMERLAIGTREVFGQRRTSSLTVRCAISFAVNWLAQRLPEYLDRY 120 Query: 145 PRIEVRVTTTMSEYFEDVKDPFDVIIWRSPLERSGYECMRFLDDVSVPLASPHFLETHPI 204 P +R+ +++ D +D FD+ I G+ R + PL +P +P+ Sbjct: 121 PGKNIRLLSSVWNDAFDAQD-FDLDIQYGTGHWPGFNSHRLTWETITPLCAPELPGRNPL 179 Query: 205 RVPRDFVEVPLIHLSSRSAAWSQWLSKAGVAVRRKMPGTVYEHSFLSLQAAATDQGVGMG 264 P+D L+H+ W WL AG G + S + + AA GV +G Sbjct: 180 NSPQDLRHHRLLHVLGYHEGWGIWLKAAGAQQVDAGSGLHLDSSLTAFELAADCAGVALG 239 Query: 265 TLALVDDDLAAGRLVRLFPEIVLHGEGYHMLCRSGAETNPALKTFITWLKQMGQAS 320 +L LA+GRL+ FP V E +H++ +G+ +P F+ WL Q S Sbjct: 240 RSSLAGHALASGRLIAPFPLAVPIDEAFHLIQPAGSSRHPDAPLFVEWLLSAVQKS 295