BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0071.p (427 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 342 9e-94 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 311 2e-84 RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 303 6e-82 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 296 5e-80 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 286 8e-77 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 283 7e-76 Z5523 [GEPR] COG0477 Permeases of the major facilitator superfam... 270 4e-72 ECs4893 [GEPR] COG0477 Permeases of the major facilitator superf... 270 4e-72 PA0703 [GEPR] COG0477 Permeases of the major facilitator superfa... 259 1e-68 RP852 [GEPR] COG0477 Permeases of the major facilitator superfam... 258 1e-68 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 342 bits (877), Expect = 9e-94, Method: Compositional matrix adjust. Identities = 181/409 (44%), Positives = 270/409 (66%), Gaps = 8/409 (1%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 R + ++ IGNALEW+D ++YG + +IA+ FFP+GD+ SLL+ ATFGV FFMRP+G V Sbjct: 12 RQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPVGGV 71 Query: 79 VLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGE 138 +LG Y+DR GRKAA+ L I+LMT+ AMIAF P+YA+IG+ AP I + +M+QGF+ GGE Sbjct: 72 LLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFATGGE 131 Query: 139 FGSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGWRVPF 197 + S+TAFLVE A PHRRG + SWQ+ Q +++ A GA++ + L E L SWGWRVPF Sbjct: 132 YASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRHLDEAPEF----KESSEKTNAPLRDTFAHQKMRLLIGAGSVIMAT 253 +FGLLI P G++IRR++ E F +E E+ L + +L+ G ++ T Sbjct: 192 LFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQG--LLGVLREYRRSVLVSMGLTVVGT 249 Query: 254 VSVYLSLY-IPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMITSS 312 VS Y+ L +PT+A KQLGLP F A +M + PL G LSD++GR P ++ ++ Sbjct: 250 VSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLVAT 309 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSL 372 ++++ YP+F ++ +P +LLL+Q ++ + +F P +A+ FPV R TG+++ Sbjct: 310 LAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGLAV 369 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASLSAR 421 AYN+AV +FGGFA I+TWL + G ++ +++V+ A L L+A+L R Sbjct: 370 AYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLR 418 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 311 bits (797), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 178/406 (43%), Positives = 247/406 (60%), Gaps = 9/406 (2%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 R+I GN LE +D ++YG +A IA FFP ++ +SL+L+ TFGV F MRPLGA+ Sbjct: 12 RSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMRPLGAL 71 Query: 79 VLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGE 138 +LGAY DR GR+A L+L++ LM GT +IA +P YA+IGL AP + +G+++QGFSAG E Sbjct: 72 ILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGFSAGVE 131 Query: 139 FGSSTAFLVE-HAPHRRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGWRVPF 197 G + +L E P R+GFF SWQ ASQ ++++ AAL G +L+ L+P+++ WGWRVPF Sbjct: 132 LGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRHLDEAPEFKESSEKTNAPLRDTFAH--QKMRLLIGAGS--VIMAT 253 + G LI P IRR L E EFK+ K L + F + R L+GAG+ V+M T Sbjct: 192 LVGCLIVPFLFLIRRSLQETEEFKQ--RKHRPALGEIFRSMGENWR-LVGAGTLLVVMTT 248 Query: 254 VSVYL-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMITSS 312 VS YL + Y PT+ L L S G F P++G++SD+IGR P +IT + Sbjct: 249 VSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLITFT 308 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSL 372 AL ++ YP +L P F +LL ++ + L Y AM L +I P A R TG SL Sbjct: 309 ALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRTTGFSL 368 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASL 418 AY++A IFGGF I TWLI TG+K ++ F A+ L+A+L Sbjct: 369 AYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATL 414 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 303 bits (775), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 170/411 (41%), Positives = 252/411 (61%), Gaps = 4/411 (0%) Query: 15 PQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRP 74 P+ R A+ ++ +GNA EWFD +YG FA VIA FP+ + +LLL ATFGV F RP Sbjct: 16 PRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGFVTRP 75 Query: 75 LGAVVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFS 134 LG +VLG Y+DR GR+ AL LS +LM +GTA+IA P+YA G+ AP + +++QGFS Sbjct: 76 LGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLLQGFS 135 Query: 135 AGGEFGSSTAFLVEHAPH-RRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGW 193 AGGE G +TA+L E AP +R F++SW AS G++++ A+ G + ++L E L +WGW Sbjct: 136 AGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALRAWGW 195 Query: 194 RVPFIFGLLIAPAGIYIRRHLDEAPEFKESSE--KTNAPLRDTFAHQKMRLLIGAGSVIM 251 R+PF G+LI P G IR LDE P F ++ + ++PL + + +LIGA VI+ Sbjct: 196 RIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADSPLLEVVRRHRRAVLIGASIVIL 255 Query: 252 ATVSVYLSL-YIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMIT 310 TV Y+ L Y+ TYA+ L LP+ + FA +G+ M + +PL G L+D++G + Sbjct: 256 WTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQRVLSG 315 Query: 311 SSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGM 370 ++ +VL YP++ +L ++P L+ +Q V G+L Y +P AD+FP TG+ Sbjct: 316 AALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKVLSTGL 375 Query: 371 SLAYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASLSAR 421 S AYN+ V + GGFA +TWL L+ +V+ A++SLI +L R Sbjct: 376 STAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALVSLIGTLWLR 426 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 296 bits (759), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 173/407 (42%), Positives = 244/407 (59%), Gaps = 9/407 (2%) Query: 19 RAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAV 78 RAI GN LE FD ++YG +A IA FFP G+ +SL+L+ TFG F MRPLGA+ Sbjct: 12 RAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMRPLGAI 71 Query: 79 VLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGE 138 VLGAY DR GR+A L+L+++LM GT +IA +P Y +IGL AP + +G+++QGFSAGGE Sbjct: 72 VLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGFSAGGE 131 Query: 139 FGSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGWRVPF 197 G + +L E A P R+GF+ SWQ SQ ++++ AAL G +L+ L+P+++ WGWRVPF Sbjct: 132 PGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWGWRVPF 191 Query: 198 IFGLLIAPAGIYIRRHLDEAPEFKESSEKTN--APLRDTFAHQKMRLLIGAGSV--IMAT 253 + G LI P +IRR L E EF++ + LR + + L GAG++ +M T Sbjct: 192 LIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWR---LAGAGTLLAVMTT 248 Query: 254 VSVYL-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMITSS 312 VS YL + Y PT+ L + + S G I P++G+LSD+IGR +I S Sbjct: 249 VSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIVFS 308 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSL 372 AL ++ YP +L P F +LL ++ + L Y AM L +I P R TG SL Sbjct: 309 ALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRTTGFSL 368 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASLS 419 AY++A IFGGF I T LI TG+K ++ F A+ L+A+L+ Sbjct: 369 AYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLT 415 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 286 bits (731), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 163/383 (42%), Positives = 229/383 (59%), Gaps = 3/383 (0%) Query: 20 AIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAVV 79 AI GN LE +D ++YG +A IAK FFP + SL+L+ ATFG F MRPLGAV Sbjct: 10 AIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLMRPLGAVF 69 Query: 80 LGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGEF 139 LGAY DR GR+ L++++ LM +GT +IAF+P YA++G+ AP + G+++QGFSAG E Sbjct: 70 LGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQGFSAGVEL 129 Query: 140 GSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGWRVPFI 198 G + +L E A P R+GFF SWQ ASQ ++++ A L G +LN L+P+ + WGWRVPF Sbjct: 130 GGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEWGWRVPFF 189 Query: 199 FGLLIAPAGIYIRRHLDEAPEFKESSEKTN-APLRDTFAHQKMRLLIGAGSVIMATVSVY 257 G LI PA IRR L+E PEF+ + + + + + + +L G V+M TVS Y Sbjct: 190 IGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVVMTTVSFY 249 Query: 258 L-SLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMITSSALYI 316 L + Y PT+ +L L S GL FI P++GA SD+IGR P ++ +SAL + Sbjct: 250 LITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLLGASALAL 309 Query: 317 VLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSLAYNI 376 + YP +L P F LL ++ + L + Y AM L ++ P R TG SLAY++ Sbjct: 310 LTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRTTGFSLAYSL 369 Query: 377 AVTIFGGFAGLIITWLIDFTGDK 399 A FGGF + TWLI ++ Sbjct: 370 ATATFGGFTPAVCTWLIHTLDNR 392 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 283 bits (723), Expect = 7e-76, Method: Compositional matrix adjust. Identities = 165/412 (40%), Positives = 246/412 (59%), Gaps = 9/412 (2%) Query: 20 AIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGAVV 79 AI+ + GN LE FD ++G +A IA+ FFP + SL+LTFA FG F MRP+GA+V Sbjct: 16 AILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFLMRPVGAIV 75 Query: 80 LGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGGEF 139 LGAY DR GR+ LM+++ +M GT +IA +P Y +IGL APA + LG+++QGFSAG E Sbjct: 76 LGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGFSAGVEL 135 Query: 140 GSSTAFLVEHA-PHRRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGWRVPFI 198 G + +L E A P +GF++SWQ ASQ +++++AAL G LN L + ++ WGWR+PF Sbjct: 136 GGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFF 195 Query: 199 FGLLIAPAGIYIRRHLDEAPEFKESSEKTNAPLRDTFAH-QKMRLLIGAGSVIMA---TV 254 G +I P +RR L E F + + + R+ FA K +I AG++++A T Sbjct: 196 IGCMIIPLIFVLRRSLQETEAFLQRKHRPDT--REIFATIAKNWRIITAGTLLVAMTTTT 253 Query: 255 SVYLSLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMITSSAL 314 ++++Y PTY L L A S + G+ FI P+ GA+SD+IGR ++ + L Sbjct: 254 FYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLL 313 Query: 315 YIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSLAY 374 ++ T+P+ +LT +P F ++ L+ MY AM A L ++ PV R G SLA+ Sbjct: 314 ALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAF 373 Query: 375 NIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASLSARLVLRL 426 ++A IFGG I T L+ TGDK S ++++ A+ L A +A L +RL Sbjct: 374 SLATAIFGGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAA--TAMLFVRL 423 >Z5523 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 438 Score = 270 bits (690), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 169/424 (39%), Positives = 247/424 (58%), Gaps = 22/424 (5%) Query: 14 HPQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFP-TGDDSVSLLLTFATFGVSFFM 72 P RR I +S+ GNALE+FD +Y F V I+ FFP + D +V+LLL FATFGVSFFM Sbjct: 14 KPSGRRVIFASAFGNALEFFDFGVYNFFVVYISTLFFPPSADKNVALLLAFATFGVSFFM 73 Query: 73 RPLGAVVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQG 132 RPLG +++GA++DR GRK A++ +I LM++GT MI P+Y + G A + L ++IQG Sbjct: 74 RPLGGIIVGAWADRFGRKPAMVFTIALMSLGTLMIGIAPTYETAGYWGTATLVLARLIQG 133 Query: 133 FSAGGEFGSSTAFLVEHAP-HRRGFFSSWQVASQGISLLLAALFGAVLNNML-------- 183 +AGGE G+S + LVE AP +RRGF+SSW +A+QG LA FG V+ L Sbjct: 134 VAAGGEVGASMSLLVESAPANRRGFYSSWSLATQG----LATTFGGVVALGLSAWLPFAT 189 Query: 184 -TPEQLASWGWRVPFIFGLLIAPAGIYIRRHLD-EAPEFKESSEKTNAPLRDTFA---HQ 238 + +A WGWRVPF G+L+AP G ++R L+ + PE + K A F+ Sbjct: 190 GSETVMAEWGWRVPFFIGVLLAPVGCWLRLSLENDVPE--PAHNKKAAASESAFSLLMQH 247 Query: 239 KMRLLIGAGSVIMATVSVYLSL-YIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGA 297 K + G I +TV+ Y+SL Y T+A K LG+ S AAM +AG+I F+G+ LVG Sbjct: 248 KATIANGILLAIGSTVATYISLFYYGTWAAKYLGMNQNYSHAAMLLAGVITFVGALLVGM 307 Query: 298 LSDKIGRTPFMITSSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALL 357 L D +GR ++ S + ++ ++P F L N P LL + V+ T+ + L+ Sbjct: 308 LCDSVGRKKLILISRVMVLICSWPSFWLLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLLI 367 Query: 358 ADIFPVATRGTGMSLAYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIAS 417 +++ P R G +L Y+I V IFGGFA T I + ++++ G +LS++A Sbjct: 368 SELLPKRIRALGFALVYSIGVAIFGGFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLAL 427 Query: 418 LSAR 421 L + Sbjct: 428 LYVK 431 >ECs4893 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 438 Score = 270 bits (690), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 169/424 (39%), Positives = 247/424 (58%), Gaps = 22/424 (5%) Query: 14 HPQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFP-TGDDSVSLLLTFATFGVSFFM 72 P RR I +S+ GNALE+FD +Y F V I+ FFP + D +V+LLL FATFGVSFFM Sbjct: 14 KPSGRRVIFASAFGNALEFFDFGVYNFFVVYISTLFFPPSADKNVALLLAFATFGVSFFM 73 Query: 73 RPLGAVVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQG 132 RPLG +++GA++DR GRK A++ +I LM++GT MI P+Y + G A + L ++IQG Sbjct: 74 RPLGGIIVGAWADRFGRKPAMVFTIALMSLGTLMIGIAPTYETAGYWGTATLVLARLIQG 133 Query: 133 FSAGGEFGSSTAFLVEHAP-HRRGFFSSWQVASQGISLLLAALFGAVLNNML-------- 183 +AGGE G+S + LVE AP +RRGF+SSW +A+QG LA FG V+ L Sbjct: 134 VAAGGEVGASMSLLVESAPANRRGFYSSWSLATQG----LATTFGGVVALGLSAWLPFAT 189 Query: 184 -TPEQLASWGWRVPFIFGLLIAPAGIYIRRHLD-EAPEFKESSEKTNAPLRDTFA---HQ 238 + +A WGWRVPF G+L+AP G ++R L+ + PE + K A F+ Sbjct: 190 GSETVMAEWGWRVPFFIGVLLAPVGCWLRLSLENDVPE--PAHNKKAAASESAFSLLMQH 247 Query: 239 KMRLLIGAGSVIMATVSVYLSL-YIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGA 297 K + G I +TV+ Y+SL Y T+A K LG+ S AAM +AG+I F+G+ LVG Sbjct: 248 KATIANGILLAIGSTVATYISLFYYGTWAAKYLGMNQNYSHAAMLLAGVITFVGALLVGM 307 Query: 298 LSDKIGRTPFMITSSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALL 357 L D +GR ++ S + ++ ++P F L N P LL + V+ T+ + L+ Sbjct: 308 LCDSVGRKKLILISRVMVLICSWPSFWLLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLLI 367 Query: 358 ADIFPVATRGTGMSLAYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIAS 417 +++ P R G +L Y+I V IFGGFA T I + ++++ G +LS++A Sbjct: 368 SELLPKRIRALGFALVYSIGVAIFGGFAQYFATQSIVLLDSLTAPAWYLGGGTLLSMLAL 427 Query: 418 LSAR 421 L + Sbjct: 428 LYVK 431 >PA0703 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 438 Score = 259 bits (661), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 164/422 (38%), Positives = 246/422 (58%), Gaps = 3/422 (0%) Query: 1 MSSNTASPGADITHPQARRAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLL 60 M S T P A P +RR++ + +GNA+E+FD +Y FAV+I + FFP+ VSLL Sbjct: 1 MRSPTRPPAA--ADPASRRSVFAVVLGNAVEFFDFGVYATFAVMIGRTFFPSDSAFVSLL 58 Query: 61 LTFATFGVSFFMRPLGAVVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLA 120 L+ FGV F +RPLGAV++GAY+DRAGRK A++L++ LM +GT IA +P Y SIG A Sbjct: 59 LSVTAFGVGFVIRPLGAVLIGAYADRAGRKPAMLLTLFLMALGTGGIAVLPGYDSIGPAA 118 Query: 121 PAGIALGKMIQGFSAGGEFGSSTAFLVEHAP-HRRGFFSSWQVASQGISLLLAALFGAVL 179 P + L +++QG + GGE G +T +++E AP H+RG ++ WQV +QGI+ + A L G +L Sbjct: 119 PLLLVLTRLLQGLAWGGEAGPATTYILEAAPPHKRGTYACWQVVAQGIAAVAAGLMGYLL 178 Query: 180 NNMLTPEQLASWGWRVPFIFGLLIAPAGIYIRRHLDEAPEFKESSEKTNAPLRDTFAHQK 239 L QL WGWR+PF GLL+ P G+YIR +L E + T L + F + + Sbjct: 179 TLWLDERQLQEWGWRIPFAAGLLVLPIGLYIRLNLAETFSGRGRQASTRNLLGELFGNHR 238 Query: 240 MRLLIGAGSVIMATVSVYLSLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALS 299 LL+G + +T++ Y Y+ T+A+ +L LPA + + VAG + + + L G L Sbjct: 239 RALLLGLLILSGSTITQYFLNYMTTFALTELHLPAGIAMLSTLVAGAALALSALLGGVLC 298 Query: 300 DKIGRTPFMITSSALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLAD 359 D+ GR +I + + +P +T P L + ++ L M AA+ LL + Sbjct: 299 DRYGRRAVLILPRLALLAVLFPALQAMTRHPEPAVFLAVLALLSALHGMSGAALIVLLVE 358 Query: 360 IFPVATRGTGMSLAYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASLS 419 FP A R TG SL Y V FGG A +++TWLI TG+ LS +++ ++ L+ + Sbjct: 359 SFPRALRSTGFSLVYATGVAAFGGTAQIVVTWLIGVTGNPLSPLGYLLLANLVCLVGAWL 418 Query: 420 AR 421 AR Sbjct: 419 AR 420 >RP852 [GEPR] COG0477 Permeases of the major facilitator superfamily Rpr Rickettsia prowazekii Length = 415 Score = 258 bits (660), Expect = 1e-68, Method: Compositional matrix adjust. Identities = 157/406 (38%), Positives = 235/406 (57%), Gaps = 12/406 (2%) Query: 18 RRAIISSSIGNALEWFDILIYGAFAVVIAKQFFPTGDDSVSLLLTFATFGVSFFMRPLGA 77 R+ II + IGNA EWFD +Y FA +I + FFP + S+ LTFA F F +RPLG Sbjct: 2 RKIIIPAMIGNAAEWFDYALYAQFAYIIGQHFFP--NSSMRDTLTFAVFAAGFIVRPLGG 59 Query: 78 VVLGAYSDRAGRKAALMLSIMLMTVGTAMIAFMPSYASIGLLAPAGIALGKMIQGFSAGG 137 ++ G DR GR+AAL++ I+ MTV TA I +PSY +IG+ AP + + ++IQGFS GG Sbjct: 60 IIFGNIGDRLGRRAALVIGIITMTVPTAGIGLLPSYNTIGIAAPIILTIIRLIQGFSLGG 119 Query: 138 EFGSSTAFLVEHAP-HRRGFFSSWQVASQGISLLLAALFGAVLNNMLTPEQLASWGWRVP 196 EF +++VEHA +RG S S +LL L + + ++ + L WGWRVP Sbjct: 120 EFSGCISYIVEHAAIEKRGLAGSASFVSMCGGMLLGLLTASGFSYFMSDDILFEWGWRVP 179 Query: 197 FIFGLLIAPAGIYIRRHLDEAPEFKESSEK---TNAPLRDTFAHQKMRLLIGAGSVIMAT 253 FI GL I G+YIR++L E+P +K++ E+ PLR+T L+I G I T Sbjct: 180 FIVGLFIGSIGLYIRKNLAESPIYKKAKERGRLARFPLRETLTQYPKELMIALGLYITVT 239 Query: 254 VSVY-LSLYIPTYAVKQLGLPAWSSFAAMSVAGLIMFIGSPLVGALSDKIGRTPFMITSS 312 Y L+++I + ++ LG S S+ ++M I P+ +SDK+GR P +I + Sbjct: 240 APFYTLTVFIGNF-MQTLGYSNQQSTIVNSIILIVMMIVFPISAYVSDKVGRRPVLICAI 298 Query: 313 ALYIVLTYPMFVFLTNSPGFLQLLLLQTVIGVLMTMYFAAMPALLADIFPVATRGTGMSL 372 L I+L YP+FV L S ++ Q + ++ Y +P +L +IFP R TG++L Sbjct: 299 ILLILLVYPIFVAL-GSMNITLAIISQVIFAGIIATYMGPIPTVLVEIFPTRVRFTGVAL 357 Query: 373 AYNIAVTIFGGFAGLIITWLIDFTGDKLSVSYFVIFGAVLSLIASL 418 +YN+A IFGG A ++ L TGD ++SY++I LSL++S+ Sbjct: 358 SYNLAAAIFGGTAPMVAMILTRITGDNYAISYYLI---ALSLLSSI 400