BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0061.p (255 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1593 [L] COG0708 Exonuclease III Rso Ralstonia solanacearum 331 1e-90 XF1933 [L] COG0708 Exonuclease III Xfa Xylella fastidiosa 9a5c 272 5e-73 all5306 [L] COG0708 Exonuclease III Nos Nostoc sp. PCC 7120 262 6e-70 sll1854 [L] COG0708 Exonuclease III Syn Synechocystis 259 3e-69 NMB0399 [L] COG0708 Exonuclease III Nme Neisseria meningitidis MC58 238 1e-62 NMA2086 [L] COG0708 Exonuclease III NmA Neisseria meningitidis Z... 237 2e-62 BMEI1093 [L] COG0708 Exonuclease III Bme Brucella melitensis 223 3e-58 CC2011 [L] COG0708 Exonuclease III Ccr Caulobacter vibrioides 214 1e-55 SMc02077 [L] COG0708 Exonuclease III Sme Sinorhizobium meliloti 213 4e-55 mlr1096 [L] COG0708 Exonuclease III Mlo Mesorhizobium loti 213 4e-55 >RSc1593 [L] COG0708 Exonuclease III Rso Ralstonia solanacearum Length = 269 Score = 331 bits (848), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 162/268 (60%), Positives = 197/268 (73%), Gaps = 13/268 (4%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEE-----NPVDVLCLQETKLTDDKFPAAEIAAAGYLVE 55 M++ATWNVNSLKVRLP VL+WL E P+D+LCLQE KL DD++P AE+ AAGY Sbjct: 1 MRVATWNVNSLKVRLPHVLQWLGEREADATPIDLLCLQELKLPDDRYPLAELEAAGYASL 60 Query: 56 FSGQKTYNGVAILSRHPM----NDVVKNNPLFPDEQQRIIAATIE----GVRYVCAYIPN 107 F+GQKTYNGVAIL+R DVV+N P F DEQQR++AAT + VR + AY PN Sbjct: 61 FTGQKTYNGVAILARKAAMPEGRDVVRNIPDFADEQQRVVAATYDVAGGPVRVISAYFPN 120 Query: 108 GQSLESEKYPYKLNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLV 167 GQ+L+S+K YK+ WLAAL +WL E A +PRL LLGD+NIAP+DRDVHDP W+G LV Sbjct: 121 GQALDSDKMVYKMRWLAALQDWLQAEMAAHPRLMLLGDFNIAPDDRDVHDPKKWEGMNLV 180 Query: 168 SEPEREAFRKLQALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPR 227 S ER AFR L++ GL D++R+FEQ +K++SWWDYR FR N GLRIDHILLS L Sbjct: 181 SPEERAAFRALESAGLVDAFRMFEQEDKLFSWWDYRLFAFRRNAGLRIDHILLSPNLARL 240 Query: 228 CTACVIDKVPRKWEQPSDHAPVIATLAD 255 C +C ID+VPR WEQPSDH PV+A L D Sbjct: 241 CESCHIDRVPRGWEQPSDHTPVVAALRD 268 >XF1933 [L] COG0708 Exonuclease III Xfa Xylella fastidiosa 9a5c Length = 264 Score = 272 bits (696), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 141/255 (55%), Positives = 178/255 (69%), Gaps = 1/255 (0%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 M+IA+WNVNSL VRL Q+ +WL E DVL LQETKL D +FP A +AA GY+ ++GQK Sbjct: 3 MRIASWNVNSLNVRLSQLQQWLVEAAPDVLGLQETKLEDHQFPEAALAALGYVSVYAGQK 62 Query: 61 TYNGVAILSRHPMNDVVKNNPLFPDEQQRIIAATIEGVRYVCAYIPNGQSLESEKYPYKL 120 TYNGVA+L+R + DV P F D Q+R+IAAT++G+R V Y+ NGQ + +EKY YKL Sbjct: 63 TYNGVALLARVALEDVQVGIPGFEDVQRRVIAATVDGIRVVNLYVVNGQEVGTEKYAYKL 122 Query: 121 NWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAW-QGQVLVSEPEREAFRKLQ 179 +WL A++ WLA+E + PRL +LGD+NIAP+ RDV+DP W + +L S ER A KL Sbjct: 123 SWLDAVYHWLAEELQRYPRLVVLGDFNIAPDARDVYDPQVWNEDHILTSTTERVALGKLL 182 Query: 180 ALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVIDKVPRK 239 LGL D +RL Q ++SWWDYRQ FR NRGLRID L+SE L + A ID VPR Sbjct: 183 GLGLHDGFRLHHQDTGIFSWWDYRQASFRRNRGLRIDLTLVSEALRAQVVASGIDCVPRG 242 Query: 240 WEQPSDHAPVIATLA 254 WE+PSDHAP LA Sbjct: 243 WERPSDHAPAWIELA 257 >all5306 [L] COG0708 Exonuclease III Nos Nostoc sp. PCC 7120 Length = 260 Score = 262 bits (669), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 127/260 (48%), Positives = 164/260 (63%), Gaps = 7/260 (2%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 MKIATWNVNS++ RL QVL WL++NPVDVLCLQETK+ DD FP + GY SGQK Sbjct: 1 MKIATWNVNSIRTRLEQVLDWLKQNPVDVLCLQETKVIDDDFPRSPFENLGYHSYISGQK 60 Query: 61 TYNGVAILSRHPMNDVVKN-NPLFPD------EQQRIIAATIEGVRYVCAYIPNGQSLES 113 YNGVA++S+ P+ DV P+ PD EQ+R+I I+GVR V Y+PNG ++ S Sbjct: 61 AYNGVALISQQPLTDVTTGFTPILPDIEPIWDEQKRVITGVIDGVRIVNLYVPNGSAIAS 120 Query: 114 EKYPYKLNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPERE 173 EKY YKL WL L E+L P + + GD+NIA ED+D+H+ V + ++ S ER+ Sbjct: 121 EKYEYKLRWLTVLREYLRSLLLLQPAICICGDFNIALEDKDIHEKVKAENHIMASLAERQ 180 Query: 174 AFRKLQALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVI 233 A R + LG D++R F +SWWDYR FR N+G RIDH L+ L + +C I Sbjct: 181 ALRDVLELGFADAFRKFTTEGGHFSWWDYRAASFRRNQGWRIDHHYLTPVLYAQAKSCTI 240 Query: 234 DKVPRKWEQPSDHAPVIATL 253 D PRK QPSDH PVI + Sbjct: 241 DVSPRKLTQPSDHTPVIVEI 260 >sll1854 [L] COG0708 Exonuclease III Syn Synechocystis Length = 275 Score = 259 bits (663), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 129/263 (49%), Positives = 167/263 (63%), Gaps = 10/263 (3%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 M IA+WNVNS++ R +L WL NPVDVLCLQETK+ D+ FP AGY SGQK Sbjct: 11 MDIASWNVNSVRSRQQHILDWLGTNPVDVLCLQETKVVDEDFPRQPFEEAGYHCHISGQK 70 Query: 61 TYNGVAILSRHPMNDVVKN-----NPLFP---DEQQRIIAATIEGVRYVCAYIPNGQSLE 112 +YNGVAI SR P+ DV P DEQ+R+I+ +GVR V Y+PNG +L+ Sbjct: 71 SYNGVAIFSREPLQDVKIGFAALVEPALTGDLDEQKRVISGVYDGVRIVNLYVPNGSALD 130 Query: 113 SEKYPYKLNWLAALHEWLAQ-EKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPE 171 SEKY YKL WL L +L Q ++ P + GD+NIAPEDRD+HDPV + ++ + E Sbjct: 131 SEKYLYKLRWLNLLQTYLEQLRRSDTPEFLVCGDFNIAPEDRDIHDPVGRENHIMATAME 190 Query: 172 REAFRKLQALG-LTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTA 230 REA ++ A+ L D++R F + YSWWDYR GF NRG RIDH L+ +L + Sbjct: 191 REALTEVLAIANLQDAFRKFTEETGHYSWWDYRTRGFSRNRGWRIDHHYLTPQLYDQAQK 250 Query: 231 CVIDKVPRKWEQPSDHAPVIATL 253 C ID+ PR WE+PSDHAPV+ T+ Sbjct: 251 CWIDREPRGWEKPSDHAPVVVTI 273 >NMB0399 [L] COG0708 Exonuclease III Nme Neisseria meningitidis MC58 Length = 256 Score = 238 bits (607), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 126/252 (50%), Positives = 159/252 (63%), Gaps = 1/252 (0%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 MKI TWNVNSL VRLPQV L +NP D+L LQE KL DKFPAA + G+ +SGQK Sbjct: 1 MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPAAALQMMGWHCVWSGQK 60 Query: 61 TYNGVAILSRHPMNDVVKNNPLFPDE-QQRIIAATIEGVRYVCAYIPNGQSLESEKYPYK 119 TYNGVAI+SR DV P PD+ Q+R+IAAT+ GVR + Y NG++L+S K+ YK Sbjct: 61 TYNGVAIVSRSVPQDVHFGLPALPDDPQRRVIAATVSGVRVINVYCVNGEALDSPKFKYK 120 Query: 120 LNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPEREAFRKLQ 179 W AAL E++ E ++ +L LLGD+NIAP D D +DP W ++ S ER+ F+ L Sbjct: 121 EQWFAALTEFVRDEMTRHGKLVLLGDFNIAPADADCYDPEKWHEKIHCSSVERQWFQNLL 180 Query: 180 ALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVIDKVPRK 239 LGLTDS R Y+W+DYR F+ GLRIDHIL+S + +D R Sbjct: 181 DLGLTDSLRQVHPEGAFYTWFDYRGAMFQRKLGLRIDHILVSPAMAAALKDVRVDLETRA 240 Query: 240 WEQPSDHAPVIA 251 E+PSDHAPV A Sbjct: 241 LERPSDHAPVTA 252 >NMA2086 [L] COG0708 Exonuclease III NmA Neisseria meningitidis Z2491 Length = 256 Score = 237 bits (605), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 126/254 (49%), Positives = 160/254 (62%), Gaps = 1/254 (0%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 MKI TWNVNSL VRLPQV L +NP D+L LQE KL DKFPAA + G+ +SGQK Sbjct: 1 MKITTWNVNSLNVRLPQVQNLLADNPPDILVLQELKLDQDKFPAAALQMMGWHCVWSGQK 60 Query: 61 TYNGVAILSRHPMNDVVKNNPLFPDE-QQRIIAATIEGVRYVCAYIPNGQSLESEKYPYK 119 TYNGVAI+SR+ DV P PD+ Q+R+IAAT+ GVR + Y NG++L+S K+ YK Sbjct: 61 TYNGVAIVSRNAPEDVHIGLPALPDDPQRRVIAATVGGVRVINVYCVNGEALDSPKFKYK 120 Query: 120 LNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPEREAFRKLQ 179 W AAL E++ E A++ +L LLGD+NIAP D D +DP W ++ S ER+ F+ L Sbjct: 121 EQWFAALTEFVRDEMARHGKLVLLGDFNIAPADADCYDPEKWHEKIHCSSVERQWFQNLL 180 Query: 180 ALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVIDKVPRK 239 LGL DS R Y+W+DYR F+ GLRIDHIL+S + +D R Sbjct: 181 DLGLADSLRQVHPEGAFYTWFDYRGAMFQRKLGLRIDHILVSPAMAEALKDVRVDLETRA 240 Query: 240 WEQPSDHAPVIATL 253 E+PSDHAPV A Sbjct: 241 LERPSDHAPVTAEF 254 >BMEI1093 [L] COG0708 Exonuclease III Bme Brucella melitensis Length = 296 Score = 223 bits (568), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 116/259 (44%), Positives = 157/259 (60%), Gaps = 5/259 (1%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 MKIATWN+N +K R+ + WL E+ D++CLQE K D++FP EI A GY VE GQK Sbjct: 37 MKIATWNINGVKARIDNLQHWLRESSPDIVCLQEIKSVDEQFPRLEIEALGYHVETHGQK 96 Query: 61 TYNGVAILSRHPMNDVVKNNPLF-PDEQQRIIA---ATIEGV-RYVCAYIPNGQSLESEK 115 +NGVA+LS+ +++ K P DEQ R I +T GV R V Y+PNG +++EK Sbjct: 97 GFNGVALLSKKSPDEINKGLPGDDSDEQARFIEGIYSTDTGVVRVVSLYLPNGNPIDTEK 156 Query: 116 YPYKLNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPEREAF 175 +PYKL+W+ L W + L L GDYN+ PE D +P AW G L R+AF Sbjct: 157 FPYKLSWMQRLENWAKKRLTLEEPLVLAGDYNVIPEPVDARNPQAWLGDALFQPQSRQAF 216 Query: 176 RKLQALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVIDK 235 R+L+ LG TD+ R +YS+WDY+ ++ N G+RIDH++LS E R + I+K Sbjct: 217 RRLENLGFTDAIRASTDESGVYSFWDYQAGAWQKNNGIRIDHLMLSPEATNRFISANIEK 276 Query: 236 VPRKWEQPSDHAPVIATLA 254 R WE+PSDH PV TLA Sbjct: 277 HVRAWEKPSDHVPVTVTLA 295 >CC2011 [L] COG0708 Exonuclease III Ccr Caulobacter vibrioides Length = 262 Score = 214 bits (546), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 115/260 (44%), Positives = 144/260 (55%), Gaps = 7/260 (2%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 M+IATWNVNS+ RL VL W E DV LQE K D+KFP GY V GQK Sbjct: 1 MRIATWNVNSINARLEGVLAWFESEAPDVAVLQEIKCVDEKFPTEAFERLGYNVAVHGQK 60 Query: 61 TYNGVAILSRHPMNDVVKNNPLFP----DEQQRIIAATIEG---VRYVCAYIPNGQSLES 113 TYNGVA+LS+HP+ DV K P DEQ R I A I R V Y+PNG + + Sbjct: 61 TYNGVALLSKHPIEDVRKGLPFLSEDEVDEQARYIEAVIAAPTPFRVVGIYLPNGNPIGT 120 Query: 114 EKYPYKLNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPERE 173 EK+ YKL+W+ LH A L + GDYN+ PE DV +P AW G L R Sbjct: 121 EKFAYKLSWMRRLHAHAQGLLAFEEPLVIAGDYNVIPEVEDVANPQAWLGDALFQPESRA 180 Query: 174 AFRKLQALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVI 233 AFR L+ LG D+Y + Y++WDY+ ++ N G+RIDH+LLS + R T VI Sbjct: 181 AFRALKNLGFADAYMQADGAPGGYTFWDYQAGAWQRNLGIRIDHLLLSPQAADRLTGLVI 240 Query: 234 DKVPRKWEQPSDHAPVIATL 253 + R E+PSDH PV+ Sbjct: 241 HRDERDKEKPSDHVPVVGRF 260 >SMc02077 [L] COG0708 Exonuclease III Sme Sinorhizobium meliloti Length = 263 Score = 213 bits (542), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 112/259 (43%), Positives = 149/259 (57%), Gaps = 5/259 (1%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 MKIATWN+N +K RL ++ WL E+ D+ CLQE K D+ FP EI A GY VE GQK Sbjct: 1 MKIATWNINGVKARLDGLVGWLRESNPDIACLQEIKSVDETFPRGEIEALGYHVETHGQK 60 Query: 61 TYNGVAILSRHPMNDVVKNNPLFP-DEQQRIIAATIE----GVRYVCAYIPNGQSLESEK 115 +NGVA+LS+ +++ + P P DEQ R I +R C Y+PNG +E+EK Sbjct: 61 GFNGVALLSKVRPDEINRGLPGDPADEQSRFIEGVFSVNGGALRVCCLYLPNGNPVETEK 120 Query: 116 YPYKLNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPEREAF 175 YPYKL W+ L + Q L L GDYN+ PE D D W+ L R AF Sbjct: 121 YPYKLAWMRRLAAFAEQRLVLEEPLILAGDYNVIPEAHDCWDVKVWRNDALYLPETRAAF 180 Query: 176 RKLQALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVIDK 235 R+L+ LG TD+ R +YS+WDY+ ++ N G+RIDH++LS E + + I+K Sbjct: 181 RRLRNLGFTDAVRATSDEAPLYSFWDYQAGCWQKNFGIRIDHLMLSPEAADKLVSTSIEK 240 Query: 236 VPRKWEQPSDHAPVIATLA 254 R WE+PSDH PV A A Sbjct: 241 HVRAWEKPSDHVPVTAEFA 259 >mlr1096 [L] COG0708 Exonuclease III Mlo Mesorhizobium loti Length = 264 Score = 213 bits (542), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 110/260 (42%), Positives = 151/260 (58%), Gaps = 6/260 (2%) Query: 1 MKIATWNVNSLKVRLPQVLKWLEENPVDVLCLQETKLTDDKFPAAEIAAAGYLVEFSGQK 60 MKI TWN+N ++ R+ + WL E+ D++CLQE K D++FP AEI A GY VE +GQK Sbjct: 1 MKIVTWNINGVRARIGNLTHWLTESAPDIVCLQEIKTVDEQFPRAEIEALGYNVETNGQK 60 Query: 61 TYNGVAILSRHPMNDVVKNNPLF-PDEQQRIIAATIE----GVRYVCAYIPNGQSLESEK 115 +NGVA+LS+ ++V++ P DEQ R I +R Y+PNG ++ EK Sbjct: 61 GFNGVALLSKLRFDEVIRGLPGDDTDEQARFIEGVFSTDKGALRVASLYLPNGNPIDDEK 120 Query: 116 -YPYKLNWLAALHEWLAQEKAKNPRLALLGDYNIAPEDRDVHDPVAWQGQVLVSEPEREA 174 +PYKLNW+A L W + L L GDYN+ PE D P W G L R+A Sbjct: 121 KFPYKLNWMARLERWAEERLKLEEALVLAGDYNVIPEPIDARFPENWLGDALFQPQTRQA 180 Query: 175 FRKLQALGLTDSYRLFEQPEKMYSWWDYRQMGFRLNRGLRIDHILLSEELVPRCTACVID 234 FR+L LG T++ R Y++WDY+ ++ N G+RIDH+LLS E R ++ I+ Sbjct: 181 FRRLLNLGFTEAVRAVTDAPDTYTFWDYQAGAWQKNNGIRIDHLLLSPEAANRFSSASIE 240 Query: 235 KVPRKWEQPSDHAPVIATLA 254 K R WE+PSDH PV LA Sbjct: 241 KHVRAWEKPSDHVPVAIDLA 260