BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0002.0024.p (269 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2013 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 231 1e-60 RSc0267 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso ... 221 2e-57 SMb21126 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sme... 170 4e-42 CC2169 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr C... 164 2e-40 PA2890 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae P... 123 5e-28 Rv0971c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu ... 114 2e-25 MT0999.1 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC... 114 2e-25 BMEI1927 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme... 114 3e-25 AGl2700 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Atu ... 113 4e-25 RSp0225 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso ... 110 3e-24 >PA2013 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 265 Score = 231 bits (589), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 119/254 (46%), Positives = 162/254 (63%) Query: 6 HLDITPRGLATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGA 65 L+I PRG+AT+ L+R E +NAF+ +I L+ + + D + LL+L G+ F GA Sbjct: 8 QLEIDPRGVATLWLDRAEKNNAFNAVVIDELLQAIDRVGSDPQVRLLVLRGRGRHFCGGA 67 Query: 66 DLAWMRRMADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVV 125 DLAWM++ D + NL DA+++A LM L + P PTLA VQGAV GGGVGLVSCCD+ + Sbjct: 68 DLAWMQQSVDLDYQGNLADAQRIAELMTHLYNLPKPTLAVVQGAVFGGGVGLVSCCDMAI 127 Query: 126 ASDAAFFALSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVAS 185 SD A F LSEV++GL PA I+P+V+ +G ARRY ++AERF RA+ +GL+ E Sbjct: 128 GSDDATFCLSEVRIGLIPATIAPFVVKAIGQRAARRYSLTAERFDGRRASELGLLSESCP 187 Query: 186 PDELDVRTAQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGR 245 EL+ + I LL N P+A+ A K L +++P L YT IA +R S EG+ Sbjct: 188 AAELESQAEAWIANLLQNSPRALVACKALYHEVEAAELSPALRRYTEAAIARIRISPEGQ 247 Query: 246 EGLRAFLDKDAPAW 259 EGLRAFL+K PAW Sbjct: 248 EGLRAFLEKRTPAW 261 >RSc0267 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso Ralstonia solanacearum Length = 264 Score = 221 bits (562), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 116/246 (47%), Positives = 157/246 (63%) Query: 14 LATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGADLAWMRRM 73 +AT+TLNRP++ NAF++ +IA L + ++LA G +F AGADL WMR+M Sbjct: 15 VATVTLNRPDVRNAFNETVIAELTGAFHALATEDSVRAIVLAGHGPAFCAGADLNWMRKM 74 Query: 74 ADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASDAAFFA 133 A S ++N DA +LA ++ +++ P P +A+V G GGVGLVS CDIVVA+D A F Sbjct: 75 AGYSDDENRADALRLAEMLRAIHACPKPVVARVHGDTYAGGVGLVSACDIVVAADTAHFC 134 Query: 134 LSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVASPDELDVRT 193 LSE +LGL PA ISPYVI +G +RRYF++AERF AA A +GLVHE+A + LD Sbjct: 135 LSEARLGLIPATISPYVIRALGEQASRRYFITAERFTAAEAHRLGLVHELAGAEALDATV 194 Query: 194 AQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGREGLRAFLD 253 L L+AN P A+R +K+LV+ + L TA IA +RAS EGREG+++FL Sbjct: 195 DALTAALVANSPNAVRESKRLVREIASAPIDDALLADTANRIAAIRASTEGREGVQSFLG 254 Query: 254 KDAPAW 259 K P W Sbjct: 255 KRKPNW 260 >SMb21126 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Sme Sinorhizobium meliloti Length = 261 Score = 170 bits (430), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 98/251 (39%), Positives = 137/251 (54%), Gaps = 1/251 (0%) Query: 9 ITPRGLATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGADLA 68 I RG+A +TL R E HNA +I L ++ + D ++L + GKSF AG DL Sbjct: 10 IDQRGVARVTLARSEKHNALSATMIGELTAVVGRLATDASIRAVILDAEGKSFCAGGDLD 69 Query: 69 WMRRMADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASD 128 WMR+ A R + +A +LA++++ LN P P +A+V G GGGVGL+S CD V+A+ Sbjct: 70 WMRQQFSADRPTRIAEATRLAMMLKALNDLPKPLIARVHGNAFGGGVGLISVCDTVIAAS 129 Query: 129 AAFFALSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVASPDE 188 A F L+E +LGL PA ISPYVIA+ G ++AR F+SA F A A G V V Sbjct: 130 GAQFGLTETRLGLIPATISPYVIARTGEARARPLFMSARVFGAEEAKVAGFVTTVVDGTM 189 Query: 189 LDVRTAQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGREGL 248 LD + L P A AK+L + L +T + T +AD + E REG+ Sbjct: 190 LDGAVEAAVTAYLVAAPGAAGRAKRLARSLG-LPITDAVIAATIEQLADTWETDEAREGV 248 Query: 249 RAFLDKDAPAW 259 AF ++ P+W Sbjct: 249 SAFFERRNPSW 259 >CC2169 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Ccr Caulobacter vibrioides Length = 262 Score = 164 bits (415), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 105/263 (39%), Positives = 140/263 (53%), Gaps = 3/263 (1%) Query: 1 MSSAAHLDITPRGLATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKS 60 MS H+D TP G T+ +NRP+ NAFD IA L ++ L G + Sbjct: 1 MSPLVHMDSTPEGAVTVWINRPDKKNAFDAATIAALRQTFETLHGAEGVRIVFLRGVGGA 60 Query: 61 FSAGADLAWMRRMADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSC 120 FSAGADL+WM + +DN +DA +LA +++ L+ P T+A V+G GGG GLV+ Sbjct: 61 FSAGADLSWMASAVEWDEDDNRQDALELAHMLKALHDIPALTVALVEGPAFGGGAGLVAA 120 Query: 121 CDIVVASDAAFFALSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLV 180 CD +A A FA SEVKLGL PA ISPYVI +G A+ F + F A A GLV Sbjct: 121 CDHALALVDAKFAFSEVKLGLTPATISPYVIQALGPRTAKLLFATGRVFDADDAWGFGLV 180 Query: 181 HEVASPDELDVRTAQ--LIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADL 238 EV D + A+ LI + P A+ AK LV ++ L + +A IA Sbjct: 181 DEVFE-DVASLEGARDALIAEMAPCAPGAIGDAKALVNDFVGQKLDKGLIDESARRIARR 239 Query: 239 RASAEGREGLRAFLDKDAPAWTR 261 R S EG+EG+RAFL + P+W Sbjct: 240 RVSPEGQEGVRAFLARRKPSWVE 262 >PA2890 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Pae Pseudomonas aeruginosa Length = 264 Score = 123 bits (308), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 86/250 (34%), Positives = 124/250 (49%), Gaps = 2/250 (0%) Query: 13 GLATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGADLAWMRR 72 G+ ITLNRP+ NA ++ L +L RDD L+L F AG D+ M Sbjct: 16 GVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCAGGDIKDMAG 75 Query: 73 MADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASDAAFF 132 A E R L+E + P +A V+GAV+GGG GL D+ +A+ A F Sbjct: 76 ARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDVAIAAADAQF 135 Query: 133 ALSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEV-ASPDELDV 191 L E LG+ PA I+P+V+ ++G++QARR ++A RF A +GLVH A D L+ Sbjct: 136 GLPETSLGILPAQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLVHFCEADADALEQ 195 Query: 192 RTAQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGREGLRAF 251 R + ++ L P A A K L+ + ++ L + A A+ AEG EG AF Sbjct: 196 RLEETLEQLRRCAPNANAATKALLLASESGELGALLDD-AARQFAEAVGGAEGSEGTLAF 254 Query: 252 LDKDAPAWTR 261 + K P W + Sbjct: 255 VQKRKPVWAQ 264 >Rv0971c [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Mtu Mycobacterium tuberculosis H37Rv Length = 269 Score = 114 bits (286), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 85/253 (33%), Positives = 122/253 (48%), Gaps = 5/253 (1%) Query: 14 LATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGADLAWMRRM 73 A +TLN P NA L++ L L+ A D L++L TG +F AGADL+ Sbjct: 17 FARLTLNSPHNRNALSSTLVSQLHQGLSAAEADPAVRLVVLGHTGGTFCAGADLSEAGGG 76 Query: 74 ADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASDAAFFA 133 + AR++ L+ + P P + + G V GG GLV CD+VVA + FA Sbjct: 77 GGDPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGGFGLVGACDMVVAGPESTFA 136 Query: 134 LSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVASPDELDVRT 193 L+E ++G+APA IS ++ K+ A RY+++ E+F A AA +GL+ A + V Sbjct: 137 LTEARIGVAPAIISLTLLPKLSPRAAARYYLTGEKFGAREAADIGLITMAADDVDAAVAA 196 Query: 194 AQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGREGLRAFLD 253 PQ + A+K L A L+ +E A L S E REG+ AFL Sbjct: 197 LVADVGR--GSPQGLAASKALTTAAV-LEGFDRDAERLTEESARLFVSDEAREGMLAFLQ 253 Query: 254 KDAPAWTRQQPTS 266 K P W QP + Sbjct: 254 KRPPRWV--QPAT 264 >MT0999.1 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase MtC Mycobacterium tuberculosis CDC1551 Length = 269 Score = 114 bits (286), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 85/253 (33%), Positives = 122/253 (48%), Gaps = 5/253 (1%) Query: 14 LATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGADLAWMRRM 73 A +TLN P NA L++ L L+ A D L++L TG +F AGADL+ Sbjct: 17 FARLTLNSPHNRNALSSTLVSQLHQGLSAAEADPAVRLVVLGHTGGTFCAGADLSEAGGG 76 Query: 74 ADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASDAAFFA 133 + AR++ L+ + P P + + G V GG GLV CD+VVA + FA Sbjct: 77 GGDPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGGFGLVGACDMVVAGPESTFA 136 Query: 134 LSEVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVASPDELDVRT 193 L+E ++G+APA IS ++ K+ A RY+++ E+F A AA +GL+ A + V Sbjct: 137 LTEARIGVAPAIISLTLLPKLSPRAAARYYLTGEKFGAREAADIGLITMAADDVDAAVAA 196 Query: 194 AQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGREGLRAFLD 253 PQ + A+K L A L+ +E A L S E REG+ AFL Sbjct: 197 LVADVGR--GSPQGLAASKALTTAAV-LEGFDRDAERLTEESARLFVSDEAREGMLAFLQ 253 Query: 254 KDAPAWTRQQPTS 266 K P W QP + Sbjct: 254 KRPPRWV--QPAT 264 >BMEI1927 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Bme Brucella melitensis Length = 142 Score = 114 bits (284), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 52/134 (38%), Positives = 77/134 (57%) Query: 6 HLDITPRGLATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGA 65 H+ + RG+A +TLNRPE HNA ++I L D+ +++L G SF AG Sbjct: 8 HIAVDQRGVARLTLNRPEQHNALSGRMIDELTTAALHLADNEAVRIVILTGAGTSFCAGG 67 Query: 66 DLAWMRRMADASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVV 125 DL WMR +A+R + +AR+LAL+++ L P P + ++ G GGGVGL+S CD + Sbjct: 68 DLGWMREQVNATRAQRIEEARKLALMLKALRDLPKPLIGRINGQAYGGGVGLISVCDAAI 127 Query: 126 ASDAAFFALSEVKL 139 + A F L+E L Sbjct: 128 SISGARFGLTETSL 141 >AGl2700 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 280 Score = 113 bits (283), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 76/244 (31%), Positives = 123/244 (50%), Gaps = 6/244 (2%) Query: 17 ITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTG-KSFSAGADLAWMRRMAD 75 +TLNRPE+HNA + + L D + A D +++ + G +SF +GADL + + Sbjct: 38 LTLNRPEVHNALNAAMTEALTDAIRAASGDGSLRAVVITAAGDRSFCSGADL----KESA 93 Query: 76 ASREDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASDAAFFALS 135 + +A +M + S P +A++ G V+ GG+GLV+ CD+ A+D A F L Sbjct: 94 GGMFLSPNGTNPIANVMRAIESCDKPVIARINGRVLAGGLGLVATCDLAYAADHAEFGLP 153 Query: 136 EVKLGLAPAAISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVASPDELDVRTAQ 195 EV++GL P ++ ++AKM + + + AA A +GLV+ A ELD + Sbjct: 154 EVRVGLFPTMVAAKLLAKMPLGGLQEMAYLGQPITAAEAKGLGLVNRTAPLAELDGLIEE 213 Query: 196 LIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGVIADLRASAEGREGLRAFLDKD 255 ++ L N P A+ A K + + L+ + IA + S E REG +AF +K Sbjct: 214 VLAKLRQNAPGAIAAGKAALLAMRDMPSDERLA-FAEDAIAAISGSDEAREGRQAFAEKR 272 Query: 256 APAW 259 P W Sbjct: 273 PPKW 276 >RSp0225 [I] COG1024 Enoyl-CoA hydratase/carnithine racemase Rso Ralstonia solanacearum Length = 277 Score = 110 bits (276), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 82/248 (33%), Positives = 114/248 (45%), Gaps = 9/248 (3%) Query: 13 GLATITLNRPEIHNAFDDQLIAHLIDLLTQARDDTRTCLLLLASTGKSFSAGADLAWMRR 72 G+A +TLNRP+ NA L +ID+L D +L+L G+S+SAG DL R Sbjct: 18 GIAWVTLNRPDKRNAMSPTLNREMIDVLETLELDGDAQVLVLTGAGESWSAGMDLKEYFR 77 Query: 73 MADAS----REDNLRDARQLALLMETLNSFPTPTLAKVQGAVMGGGVGLVSCCDIVVASD 128 D +E RD Q + L + PT+A V G GG + CD+ +A+D Sbjct: 78 ETDGQPEIMQERIRRDCSQWQWKL--LRFYSKPTIAMVNGWCFGGAFSPLVACDLAIAAD 135 Query: 129 AAFFALSEVKLGLAPAA-ISPYVIAKMGVSQARRYFVSAERFPAARAAAMGLVHEVASPD 187 A F LSE+ G+ P +S V MG A Y ++ E F AA MGLV+ + Sbjct: 136 DAVFGLSEINWGIPPGNLVSKAVADTMGHRAALHYIMTGETFTGREAAEMGLVNRSVPRE 195 Query: 188 ELDVRTAQLIDTLLANGPQAMRAAKQLVQVANPLQVTPELSEYTAGV-IADLRASAEGRE 246 L +L LLA P +R AK + L A V ++ R +GR+ Sbjct: 196 RLREAVTELAGKLLAKNPVVLRYAKHGFKRCRELSWEQNEDYLYAKVDQSNHRDPEKGRQ 255 Query: 247 -GLRAFLD 253 GL+ FLD Sbjct: 256 HGLKQFLD 263