BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0094.p (141 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1774 [KR] COG0454 Histone acetyltransferase HPA2 and related ... 159 2e-39 SA0906 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 107 7e-24 PA2631 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 97 7e-21 VNG1398C [KR] COG0454 Histone acetyltransferase HPA2 and related... 97 1e-20 MA2443 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 89 2e-18 BH1438 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 84 7e-17 lin0975 [KR] COG0454 Histone acetyltransferase HPA2 and related ... 84 1e-16 BS_yjcF [KR] COG0454 Histone acetyltransferase HPA2 and related ... 79 2e-15 VC2740 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 79 3e-15 L67527 [KR] COG0454 Histone acetyltransferase HPA2 and related a... 78 6e-15 >RSc1774 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Rso Ralstonia solanacearum Length = 148 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 81/131 (61%), Positives = 95/131 (72%) Query: 8 WDAMRAHAQPIRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRLLPDGHIG 67 WDA+R A +R+DVFV EQ VP E+E D+ DA HAVA D +G+ +ATGRLLPDGHIG Sbjct: 18 WDALRDEAGAVRYDVFVIEQNVPVELEWDDDDARSWHAVARDASGRAVATGRLLPDGHIG 77 Query: 68 RMAVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGFVQEGEIFLEA 127 RMAVRK RG G+G VLQAL+ ARA G +++LNAQTHA PFYA GF EG+ F EA Sbjct: 78 RMAVRKEARGTGIGARVLQALIDKARALGYTQLILNAQTHAMPFYARAGFTPEGDEFEEA 137 Query: 128 GIEHITMRASL 138 GI H TMR L Sbjct: 138 GIAHRTMRRVL 148 >SA0906 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Sau Staphylococcus aureus N315 Length = 144 Score = 107 bits (268), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 58/126 (46%), Positives = 75/126 (59%), Gaps = 5/126 (3%) Query: 18 IRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRLLPDGH----IGRMAVRK 73 IR VFV+EQ VP E E+DE ++ IH + YD GQP+AT R+ P I R+AV K Sbjct: 17 IRKKVFVEEQGVPEESEIDEYESESIHLIGYDN-GQPVATARIRPINETTVKIERVAVMK 75 Query: 74 AGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGFVQEGEIFLEAGIEHIT 133 + RG+G+G ++QA+ A+ G +NAQ HA PFY + F G IFLE GIEHI Sbjct: 76 SHRGQGMGRMLMQAVESLAKDEGFYVATMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIE 135 Query: 134 MRASLA 139 M L Sbjct: 136 MTKKLT 141 >PA2631 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Pae Pseudomonas aeruginosa Length = 141 Score = 97.4 bits (241), Expect = 7e-21, Method: Compositional matrix adjust. Identities = 54/134 (40%), Positives = 76/134 (56%), Gaps = 1/134 (0%) Query: 1 MNIITGSWDAMRAHAQPIRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRL 60 + + W A + IR VF+ EQ VP E+E D D +H +AY E + T RL Sbjct: 4 IRVRVADWQKDNAELRRIREAVFIAEQSVPPELEWDAEDDEAVHFLAY-EGEYAIGTARL 62 Query: 61 LPDGHIGRMAVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGFVQE 120 L DGHIGR++V K RG VG A+++A ++ A RG + +L AQ +A PFY GF + Sbjct: 63 LGDGHIGRVSVLKDWRGLKVGDALMRAAIEEAERRGLKRQLLTAQVYAIPFYERLGFKVD 122 Query: 121 GEIFLEAGIEHITM 134 FL+AG+ H+ M Sbjct: 123 SGEFLDAGLPHVDM 136 >VNG1398C [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Hbs Halobacterium sp. NRC-1 Length = 147 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 62/148 (41%), Positives = 82/148 (55%), Gaps = 11/148 (7%) Query: 1 MNIITGSWDAMRAHAQPIRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDE-------AGQ 53 M +I + A +RF VFVDEQ VPA++E+D+ D H VAYD Sbjct: 1 MRVIRATTTEEYEDALRVRFAVFVDEQGVPADMEVDDHDDTATHFVAYDTMTGSQDATRA 60 Query: 54 PLATGRLLPDGHIG---RMAVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAP 110 A +G +G R+AVR + RG GVG V+ A+ AAR R E+ L+AQ+ A Sbjct: 61 VAAARLRAYEGSVGKVERVAVRASRRGNGVGATVMDAVEDAARERF-AELYLHAQSRVAE 119 Query: 111 FYAAHGFVQEGEIFLEAGIEHITMRASL 138 FYA G+ +EGE F+EAGIEH+ MR L Sbjct: 120 FYATRGYHREGEPFMEAGIEHVAMRKRL 147 >MA2443 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Mac Methanosarcina acetivorans str.C2A Length = 169 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 51/120 (42%), Positives = 69/120 (57%), Gaps = 4/120 (3%) Query: 18 IRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRLLPDGH---IGRMAVRKA 74 +R +VF+ EQ + ELDE D H V Y + +P+ATGR + IGR++V K Sbjct: 28 VRREVFIKEQNISEAEELDEADLSSRHIVVY-ASDRPVATGRFFSNEKTWLIGRISVLKE 86 Query: 75 GRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGFVQEGEIFLEAGIEHITM 134 RGK +G V++ L++ A V ++AQTHA FY GFV E FLEA IEHI+M Sbjct: 87 CRGKQIGKLVVEKLLEKAVELEAGAVHIHAQTHAVSFYEKFGFVAYRETFLEANIEHISM 146 >BH1438 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Bha Bacillus halodurans Length = 144 Score = 84.3 bits (207), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 53/142 (37%), Positives = 74/142 (52%), Gaps = 4/142 (2%) Query: 1 MNIITGSWDAMRAHAQPIRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRL 60 MN+I D +R +VF+ EQ VP E E+DE + H V YD+ QP+ GRL Sbjct: 1 MNVIIAETDQQLEDGFHVRREVFIKEQHVPEEEEIDEYEEEATHFVLYDDQAQPVGAGRL 60 Query: 61 ----LPDGHIGRMAVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHG 116 G I R+ + K RG G G +++++ A G ++ LNAQTHA FY G Sbjct: 61 RTISTDVGKIERICIMKQARGTGAGKLLMESIESFAHKVGVHKLKLNAQTHAEGFYERLG 120 Query: 117 FVQEGEIFLEAGIEHITMRASL 138 F E F +AGI H+TM ++ Sbjct: 121 FKTVSERFFDAGIPHVTMVKTI 142 >lin0975 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Lin Listeria innocua Length = 145 Score = 83.6 bits (205), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 52/130 (40%), Positives = 71/130 (54%), Gaps = 5/130 (3%) Query: 15 AQPIRFDVFVDEQQVPAEIELDEMD--AHCIHAVAYDEAGQPLATGRL-LPDGH--IGRM 69 A IR DVFV EQ V +E DE D A V Y E G LATGR + DG+ + R+ Sbjct: 15 ALKIRNDVFVVEQNVDPALEWDEFDEMASVDMFVDYAEDGTALATGRFRVKDGYGKVERI 74 Query: 70 AVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGFVQEGEIFLEAGI 129 +K RG G G +++A+ A+ RG + L AQ A PFY G+ ++FL+AGI Sbjct: 75 CTQKIARGSGSGRRIMEAIELEAKTRGLTTLKLGAQLTAIPFYEKLGYETCSDVFLDAGI 134 Query: 130 EHITMRASLA 139 +H M+ +L Sbjct: 135 KHKEMKKTLT 144 >BS_yjcF [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Bsu Bacillus subtilis Length = 140 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 54/121 (44%), Positives = 75/121 (61%), Gaps = 5/121 (4%) Query: 18 IRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRL-LPDGH--IGRMAVRKA 74 +R +VFV EQ VPAE E+DE++ H V YD +P+ GR + DG+ + R+ V K+ Sbjct: 18 VREEVFVKEQNVPAEEEIDELENESEHIVVYD-GEKPVGAGRWRMKDGYGKLERICVLKS 76 Query: 75 GRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGF-VQEGEIFLEAGIEHIT 133 R GVGG +++AL +AA G +LNAQT A PFY HG+ V + FL+AGI H+ Sbjct: 77 HRSAGVGGIIMKALEKAAADGGASGFILNAQTQAVPFYKKHGYRVLSEKEFLDAGIPHLQ 136 Query: 134 M 134 M Sbjct: 137 M 137 >VC2740 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Vch Vibrio cholerae Length = 310 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 52/145 (35%), Positives = 73/145 (50%), Gaps = 5/145 (3%) Query: 1 MNIITGSWDAMRAHAQPIRFDVFVDEQQVPAEIELDEMDAHCIHAVAYDEAGQPLATGRL 60 +IT + D R+ + + ++P E DE D+ H + D G P+A GRL Sbjct: 4 FKLITPTTDNQLNKYFHFRWQMLREPWRMPIGSERDEYDSMSHHRMIVDSRGYPMAIGRL 63 Query: 61 L--PD--GHIGRMAVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHG 116 PD G I MAV+ R KG+G +L AL AR G + +V NA+ A PFYA +G Sbjct: 64 YITPDCEGQIRYMAVKANRRSKGMGSLILVALESLARQEGAKRLVCNAREDAIPFYAKNG 123 Query: 117 FVQEGEIFLEAG-IEHITMRASLAP 140 F + GE+ E G + H M +L P Sbjct: 124 FERRGELTDERGPVRHQQMVKTLDP 148 >L67527 [KR] COG0454 Histone acetyltransferase HPA2 and related acetyltransferases Lla Lactococcus lactis Length = 147 Score = 78.2 bits (191), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 52/138 (37%), Positives = 75/138 (54%), Gaps = 13/138 (9%) Query: 8 WDAMRAHAQPIRFDVFVDEQQVPAEIELDEM--DAHCIHAVAYDEAGQPLATGRLLPD-- 63 +DA+R IR VFV EQ VP E+E+ +A +H V YD+ G T RLL D Sbjct: 15 FDALR-----IRNQVFVKEQGVPYELEVGNALEEASSVHFVLYDD-GLAKGTVRLLADLD 68 Query: 64 ---GHIGRMAVRKAGRGKGVGGAVLQALMQAARARGDREVVLNAQTHAAPFYAAHGFVQE 120 I RMA+ K RG G ++ L++ A+ ++ L+AQ A Y+ HGF + Sbjct: 69 DKTALIQRMAILKEARGHGYATLLINRLIEFAKENRLNKLELHAQLSAKGLYSKHGFNEV 128 Query: 121 GEIFLEAGIEHITMRASL 138 G++F EAGI+HI M ++ Sbjct: 129 GQVFEEAGIQHIQMERTI 146