BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0073.p (490 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2390 [H] COG1492 Cobyric acid synthase Rso Ralstonia solanace... 630 e-180 PA1277 [H] COG1492 Cobyric acid synthase Pae Pseudomonas aeruginosa 616 e-176 VCA0727 [H] COG1492 Cobyric acid synthase Vch Vibrio cholerae 572 e-163 CC1751 Non COG 416 e-116 CAC1374 [H] COG1492 Cobyric acid synthase Cac Clostridium acetob... 412 e-115 mll1198 [H] COG1492 Cobyric acid synthase Mlo Mesorhizobium loti 412 e-115 CC2694 Non COG 409 e-114 STM2019 [H] COG1492 Cobyric acid synthase Sty Salmonella typhimu... 399 e-110 SMc04309 [H] COG1492 Cobyric acid synthase Sme Sinorhizobium mel... 398 e-110 BMEI0690 [H] COG1492 Cobyric acid synthase Bme Brucella melitensis 388 e-107 >RSc2390 [H] COG1492 Cobyric acid synthase Rso Ralstonia solanacearum Length = 495 Score = 630 bits (1624), Expect = e-180, Method: Compositional matrix adjust. Identities = 335/473 (70%), Positives = 375/473 (79%), Gaps = 6/473 (1%) Query: 5 PFHTLMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQA 64 P TLMIQGTTSDAGKSTL A LCR+ + GV VAPFKPQNMALNSAVT+DGGEIGRAQA Sbjct: 10 PRGTLMIQGTTSDAGKSTLVAGLCRIAHRAGVRVAPFKPQNMALNSAVTADGGEIGRAQA 69 Query: 65 LQAQAAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYA 124 LQAQAAG+AP DMNPVLLKP+SDTGAQVI+HG+ R D+NAR YH YK AM AVL S+ Sbjct: 70 LQAQAAGLAPTVDMNPVLLKPNSDTGAQVIIHGRPRGDLNARAYHDYKPTAMAAVLASHG 129 Query: 125 RLRAQYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTL 184 RLRAQY V+VEGAGSPAE+NLRAR IANMGFAEAVDCPV++VADIDRGGVFAHL GTL Sbjct: 130 RLRAQYDLVLVEGAGSPAEVNLRAR-DIANMGFAEAVDCPVVLVADIDRGGVFAHLVGTL 188 Query: 185 DCLSESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGLHLDAEDAVA 244 CLSESERARV GFVINRFRGD+SLL GLDWL +TGKPV VLPYL GLHLDAEDAV Sbjct: 189 ACLSESERARVTGFVINRFRGDLSLLTPGLDWLTAQTGKPVFGVLPYLQGLHLDAEDAVQ 248 Query: 245 ATQE-VKGE-FRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPPADLIILPGSKN 302 Q GE R+V+PV PRISNHTDFDALRAHP VD+R +GPG+P+PPADL+ILPGSK+ Sbjct: 249 TAQSAASGEVLRVVIPVLPRISNHTDFDALRAHPQVDVRMVGPGRPIPPADLVILPGSKS 308 Query: 303 TRGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLL 362 + DL WLR HGW+AAIARHLRYGGK+IGICGG QMLG + DP G+EG PGS GLG L Sbjct: 309 VQADLAWLRAHGWDAAIARHLRYGGKLIGICGGMQMLGRRLRDPLGLEGRPGSLDGLGYL 368 Query: 363 AMRTELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVI-EGRGEGAQS 421 T L K+L QV G A D A + GYEIHMGV+ G AL RPA + +GR +GA S Sbjct: 369 DFETTLAPAKQLRQVRGTLA--DGGAALAGYEIHMGVTEGPALARPAVRLDDGRTDGAVS 426 Query: 422 ADGQILGSYLHGMFDTPQALGVLLDWAGLAGAEPVDLDALREVSLERLAESCR 474 ADGQIL +YLHG+FD P+A LL WAG+ A D ALRE SLERLA++ R Sbjct: 427 ADGQILATYLHGLFDAPEACRALLAWAGVREARAQDYAALREASLERLADTLR 479 >PA1277 [H] COG1492 Cobyric acid synthase Pae Pseudomonas aeruginosa Length = 490 Score = 616 bits (1588), Expect = e-176, Method: Compositional matrix adjust. Identities = 312/467 (66%), Positives = 366/467 (78%), Gaps = 6/467 (1%) Query: 8 TLMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQA 67 TLM+QGTTSDAGKSTL ALCR L + GV+V PFKPQNMALNSAVT+DGGEIGRAQA+QA Sbjct: 7 TLMVQGTTSDAGKSTLVTALCRWLARRGVAVVPFKPQNMALNSAVTADGGEIGRAQAVQA 66 Query: 68 QAAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARLR 127 QA +APHTDMNPVLLKP++D GAQVI+HG+ M+A YH YK AM+AVL S+ RL Sbjct: 67 QACRLAPHTDMNPVLLKPNTDIGAQVIIHGRAVTSMDAAAYHDYKRVAMEAVLASHGRLA 126 Query: 128 AQYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDCL 187 A Y V+VEGAGSPAEINLRA IANMGFAEAVDCPVI+VADIDRGGVFAHL GTL+ L Sbjct: 127 AAYRVVMVEGAGSPAEINLRAN-DIANMGFAEAVDCPVILVADIDRGGVFAHLVGTLELL 185 Query: 188 SESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGLHLDAEDAVAATQ 247 S+SER RV GFVINRFRGDI+LLQ GLDWLE RTGKPVL VLPY+ LHL+AEDA+ Q Sbjct: 186 SDSERERVKGFVINRFRGDIALLQPGLDWLEARTGKPVLGVLPYVSDLHLEAEDAIDTRQ 245 Query: 248 EVK--GEFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPPADLIILPGSKNTRG 305 K ++VVPV PRISNHTDFD LR HP V+L F+GPG+ +P ADLI+LPGSK+ R Sbjct: 246 AAKVGPRLKVVVPVLPRISNHTDFDPLRLHPQVELSFVGPGQALPSADLIVLPGSKSVRA 305 Query: 306 DLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLLAMR 365 DL LRE GW+ AI RHLRYGG+++GICGG QMLGE + DP G+EGA GSSAGLGLLA+ Sbjct: 306 DLAALRERGWDEAILRHLRYGGRLLGICGGLQMLGERLHDPLGLEGAAGSSAGLGLLALE 365 Query: 366 TELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVI-EGRGEGAQSADG 424 T L DK+L V G ++ D AP+ GYEIH GV+ G AL RPA V+ +GR +GA+S DG Sbjct: 366 TTLEADKQLRNVQGRLSLED--APLSGYEIHAGVTRGEALARPAVVLDDGRADGARSVDG 423 Query: 425 QILGSYLHGMFDTPQALGVLLDWAGLAGAEPVDLDALREVSLERLAE 471 ++G+YLHG+F++ A LL WAGL + VD ALRE +ERLA+ Sbjct: 424 NVMGTYLHGLFESTAACSALLRWAGLREVQAVDYQALRERDIERLAD 470 >VCA0727 [H] COG1492 Cobyric acid synthase Vch Vibrio cholerae Length = 484 Score = 572 bits (1473), Expect = e-163, Method: Compositional matrix adjust. Identities = 288/467 (61%), Positives = 347/467 (74%), Gaps = 4/467 (0%) Query: 9 LMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQAQ 68 LM+QGTTSDAGKS L A LCR+L + G+ V PFKPQNMALNSAVT DGGEIGRAQA+QAQ Sbjct: 5 LMVQGTTSDAGKSVLVAGLCRVLARRGIQVCPFKPQNMALNSAVTPDGGEIGRAQAVQAQ 64 Query: 69 AAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARLRA 128 A GIAP MNPVLLKP+SDTGAQVI+ G+ ++M A YH YK AM V+ S+ RL+ Sbjct: 65 ACGIAPSVHMNPVLLKPNSDTGAQVILQGRALSNMEANAYHDYKKVAMDTVMDSFQRLQQ 124 Query: 129 QYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDCLS 188 +Y +++EGAGSPAEINLR IANMGFAE D PVIIVADIDRGGVFAHL GTL LS Sbjct: 125 EYEAIMIEGAGSPAEINLREN-DIANMGFAEKADVPVIIVADIDRGGVFAHLYGTLALLS 183 Query: 189 ESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGLHLDAEDAVAATQE 248 ESE+ARV GFVINRFRGDI LLQ+GLDWLEQ+TGKPV+ VLPYLHG L+AEDA+AA Q Sbjct: 184 ESEQARVKGFVINRFRGDIGLLQSGLDWLEQKTGKPVIGVLPYLHGFDLEAEDAIAAQQN 243 Query: 249 VKG--EFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPPADLIILPGSKNTRGD 306 + + R+ VPVF RISNHTDFD LR +P +D R++G G+ + ADLIILPGSK+TR D Sbjct: 244 LSADRQLRVAVPVFTRISNHTDFDPLRLNPNIDFRYVGQGESLSGADLIILPGSKSTRAD 303 Query: 307 LRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLLAMRT 366 L +LR GW+ I RHLR GGKV+GICGGFQMLGE V DP G+EG GSS GLGL AM+T Sbjct: 304 LAYLRSQGWDKEILRHLRLGGKVMGICGGFQMLGEWVHDPLGIEGEAGSSEGLGLFAMQT 363 Query: 367 ELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALER-PAFVIEGRGEGAQSADGQ 425 ELT +KRL V GH + ++ +GYEIH G SS AA ++ P + +G +G S Q Sbjct: 364 ELTAEKRLTNVKGHLTLDGQTVAAQGYEIHAGHSSWAADQKSPIILSDGSLDGLVSDCNQ 423 Query: 426 ILGSYLHGMFDTPQALGVLLDWAGLAGAEPVDLDALREVSLERLAES 472 G+YLHG+FD P+ + WAG E D A +E +++R+A++ Sbjct: 424 GFGTYLHGIFDRPETALRICQWAGAKEIEAYDHRAAQERAIDRIADA 470 >CC1751 Non COG Length = 484 Score = 416 bits (1069), Expect = e-116, Method: Compositional matrix adjust. Identities = 233/434 (53%), Positives = 287/434 (66%), Gaps = 12/434 (2%) Query: 9 LMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQAQ 68 LMIQG SD GKS L A LCR+ G +V PFKPQNM+ N+AVT+DGGEIGRAQALQA Sbjct: 4 LMIQGCGSDVGKSVLVAGLCRVFANRGFAVRPFKPQNMSNNAAVTADGGEIGRAQALQAI 63 Query: 69 AAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARLRA 128 A AP DMNPVLLKP SD GAQV+V G++ AR Y +K + V++S+ L Sbjct: 64 ACRTAPTVDMNPVLLKPQSDIGAQVVVRGRMAGSWAARGYQDHKASLLPTVVESFRTLER 123 Query: 129 QYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDCLS 188 Q VIVEGAGSPAEINLR IANMGFA A D PV++V DIDRG V A L G L Sbjct: 124 QSDLVIVEGAGSPAEINLRV-GDIANMGFARAADVPVVLVGDIDRGHVIAALVGAHAVLD 182 Query: 189 ESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGL-HLDAEDAV---A 244 +RA + GF+IN+FRGD +L G + +RTG L + P+L L AEDAV A Sbjct: 183 PEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVLDA 242 Query: 245 ATQEVKGEFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVP-PADLIILPGSKNT 303 + G+ RIVVP+ RI+N +FDALRA PGV+ F+ PG +P ADL+ILPG+K T Sbjct: 243 RSAGRGGKVRIVVPMLSRIANFDEFDALRAEPGVEFAFVPPGSALPGDADLVILPGTKAT 302 Query: 304 RGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLLA 363 R DL ++R GW+ + HLR GG+V+GICGG+QMLG V DP GVEGAPG+S GLGLL Sbjct: 303 RADLDFVRAQGWDIDLRAHLRRGGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGLLD 362 Query: 364 MRTELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVIE-GRGEGAQSA 422 + T +T DK L V+G D A GYE+H+G +SGAA RP + + G +GA SA Sbjct: 363 VETVMTGDKTLRPVTGRL---DGCARFEGYEMHVGRTSGAA--RPMLIFDTGEPDGAVSA 417 Query: 423 DGQILGSYLHGMFD 436 DG+I G Y+HG+FD Sbjct: 418 DGRISGCYVHGLFD 431 >CAC1374 [H] COG1492 Cobyric acid synthase Cac Clostridium acetobutylicum Length = 491 Score = 412 bits (1060), Expect = e-115, Method: Compositional matrix adjust. Identities = 215/474 (45%), Positives = 293/474 (61%), Gaps = 12/474 (2%) Query: 9 LMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQAQ 68 +MIQGT S GKS L AALCR+ K+DG SV P+K QNM+LNS +T DG E+GRAQ LQA Sbjct: 4 IMIQGTASSVGKSILVAALCRIFKQDGFSVCPYKSQNMSLNSYITLDGKEMGRAQVLQAY 63 Query: 69 AAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARLRA 128 AAG+ P MNP+LLKP++D QVIV G+V +A++Y+ K E + + + L Sbjct: 64 AAGLEPEVYMNPILLKPTTDKSCQVIVKGEVYGVSSAKNYYNMKKEFAPMLKEDFEELED 123 Query: 129 QYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDCLS 188 ++ V++EGAGSPAEINLR I NMG AE VD PV++V DID+GGVFA L GT+ L Sbjct: 124 KFDIVVIEGAGSPAEINLREN-DIVNMGLAELVDAPVVLVGDIDKGGVFASLFGTVMLLE 182 Query: 189 ESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGLHLDAED-AVAATQ 247 E+ER R+ G +IN+FRGD+ +L+ GL LE+R P V+PY + L L+ ED AV Sbjct: 183 ENERKRIKGTIINKFRGDVEILKPGLSMLEERINIPCFGVVPYFN-LSLEDEDGAVYFNT 241 Query: 248 EVKGEFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPPADLIILPGSKNTRGDL 307 +V + + V P ISN TD DAL+ V LR+I + DL+I+PGSKNT GDL Sbjct: 242 KVNSKIDVAVIKLPHISNFTDIDALKIEEDVSLRYITSSENFGTPDLLIIPGSKNTIGDL 301 Query: 308 RWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLLAMRTE 367 ++R++G E I ++ G + GICGG+QMLG ++DP VE G G+GLL +RT Sbjct: 302 LYIRKNGIENKIKQYAEKNGLIFGICGGYQMLGRLIEDPFKVETELGEINGMGLLDIRTV 361 Query: 368 LTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVIEGR---GEGAQSADG 424 K +V G +V D+ PV GYEIHMG+SS +P IE + +GA + G Sbjct: 362 FAEKKVTTRVQG--SVIDKQIPVYGYEIHMGISSYGEKAKPFIKIENKVGIDDGAVNEGG 419 Query: 425 QILGSYLHGMFDTPQ----ALGVLLDWAGLAGAEPVDLDALREVSLERLAESCR 474 I+G+Y+HG+FD + L D G+ + V + +R ++RLA+ R Sbjct: 420 NIMGTYIHGIFDGANFREYIINFLRDKKGIERKKSVVYEDVRNGEIDRLADIVR 473 >mll1198 [H] COG1492 Cobyric acid synthase Mlo Mesorhizobium loti Length = 491 Score = 412 bits (1059), Expect = e-115, Method: Compositional matrix adjust. Identities = 225/458 (49%), Positives = 293/458 (63%), Gaps = 15/458 (3%) Query: 7 HTLMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTS-------DGGEI 59 +M+QGT SD GK+ L A LCR KK G+ V PFKPQNM+ N+AV GGEI Sbjct: 3 RAIMLQGTGSDVGKTVLVAGLCRAAKKRGLKVRPFKPQNMSNNAAVADIPGDNNHGGGEI 62 Query: 60 GRAQALQAQAAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAV 119 GRAQ LQA A G+AP MNPVLLKP SD GAQVIV GKV + ARDY K M AV Sbjct: 63 GRAQWLQAIACGVAPSVHMNPVLLKPQSDVGAQVIVQGKVFGEARARDYQALKGRLMDAV 122 Query: 120 LQSYARLRAQYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAH 179 L S+A++ VIVEGAGSPAEINLR+R IANMGFA D PV++V DIDRGGV A Sbjct: 123 LDSWAKVGEGADLVIVEGAGSPAEINLRSR-DIANMGFATRADVPVVLVGDIDRGGVIAS 181 Query: 180 LTGTLDCLSESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLH-GLHLD 238 + GT L E +R ++G++IN+FRGD+SL GL +E+ TG V+P+L L Sbjct: 182 VAGTHLILPEEDRRMIVGYLINKFRGDVSLFDDGLKAIEKFTGWRCFGVVPWLKAAARLP 241 Query: 239 AEDAVAATQEVKGE---FRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPP-ADL 294 +ED+V + GE ++ VPV RI+N D D L+A P V++ F+ PGKP+P A L Sbjct: 242 SEDSVVLERLASGEARALKVAVPVLGRIANFDDLDPLKAEPQVEVVFVPPGKPLPSDAGL 301 Query: 295 IILPGSKNTRGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPG 354 +++PGSK+T GDL RE+GW+ +A H + GG V+GICGGFQMLG V DP G+EG+ Sbjct: 302 VVIPGSKSTIGDLIRFRENGWDRDLATHRKRGGHVVGICGGFQMLGRRVRDPDGIEGSVT 361 Query: 355 SSAGLGLLAMRTELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVIEG 414 + GLGLL + T + +K + VS D P+ GYEIH+G ++G RP+ +I G Sbjct: 362 EAEGLGLLDIETMMEPEKTVRNVSARSVQFD--LPLEGYEIHLGRTTGPDTMRPSAIING 419 Query: 415 RGEGAQSADGQILGSYLHGMFDTPQALGVLLDWAGLAG 452 +GA SADG+++G+Y+HG+F G L+ G+ G Sbjct: 420 VADGAISADGKVIGTYMHGLFGADAFRGKFLESLGIKG 457 >CC2694 Non COG Length = 484 Score = 409 bits (1052), Expect = e-114, Method: Compositional matrix adjust. Identities = 239/483 (49%), Positives = 306/483 (63%), Gaps = 15/483 (3%) Query: 9 LMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQAQ 68 LMIQG SD GKS L A LCRL G +V PFKPQNM+ N+AVT++GGEIGRAQALQA Sbjct: 4 LMIQGCGSDVGKSVLVAGLCRLFANRGFAVRPFKPQNMSNNAAVTAEGGEIGRAQALQAI 63 Query: 69 AAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARLRA 128 A P +MNPVLLKP SD GAQV+V G++ A Y +K + V++S+ L Sbjct: 64 ACRTPPTVEMNPVLLKPQSDIGAQVVVRGRMAGSWAASGYQDHKASLLPIVVESFRALER 123 Query: 129 QYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDCLS 188 Q VIVEGAGSPAEINLRA IANMGFA A D PV++V DIDRG V A L G L Sbjct: 124 QSDLVIVEGAGSPAEINLRA-GDIANMGFARAADVPVVLVGDIDRGHVIAALVGAHAVLD 182 Query: 189 ESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGL-HLDAEDAV---A 244 +RA + GF+IN+FRGD +L G + +RTG L + P+L L AEDAV A Sbjct: 183 PEDRAMIKGFLINKFRGDPALFDDGRRAIVERTGWADLGMAPWLAAARRLPAEDAVVLDA 242 Query: 245 ATQEVKGEFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVP-PADLIILPGSKNT 303 + G RIVVP+ RI+N +FDALRA PGV F+ PG +P AD++ILPG+K T Sbjct: 243 RSAGRDGRIRIVVPMLSRIANFDEFDALRAEPGVAFAFVPPGSALPGDADVVILPGTKAT 302 Query: 304 RGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLLA 363 R DL ++R GW+ + HLR G+V+GICGG+QMLG V DP GVEGAPG+S GLGLL Sbjct: 303 RADLDFVRAQGWDIDLQAHLRRSGRVLGICGGYQMLGRRVADPDGVEGAPGTSEGLGLLD 362 Query: 364 MRTELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVIE-GRGEGAQSA 422 + T +T DK L V+G G R GYE+H+G +SGAA RP + G +GA SA Sbjct: 363 VETVMTGDKTLRPVTGRLPGGAR---FEGYEMHVGRTSGAA--RPMLTFDTGETDGAVSA 417 Query: 423 DGQILGSYLHGMFDTPQALGVLLDWAGLAGAEPVDLDALREVSLERLAESCRPLYE--AL 480 DG++ G Y+HG+FD +A LL G+A ++ D +++L+ +A + ++ +L Sbjct: 418 DGRVSGCYVHGLFDRGEARAALLAELGVA-SDAADQAVRVDLALDEIAAALESAFDIRSL 476 Query: 481 QRL 483 RL Sbjct: 477 ARL 479 >STM2019 [H] COG1492 Cobyric acid synthase Sty Salmonella typhimurium LT2 Length = 506 Score = 399 bits (1024), Expect = e-110, Method: Compositional matrix adjust. Identities = 219/447 (48%), Positives = 282/447 (63%), Gaps = 20/447 (4%) Query: 7 HTLMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQ 66 +M+QGT SD GKS LAA LCR+ +DG+ APFK QNMALNS +T DG E+GRAQ Q Sbjct: 3 QAVMLQGTASDVGKSVLAAGLCRIFYQDGLRTAPFKSQNMALNSGITPDGKEMGRAQIFQ 62 Query: 67 AQAAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARL 126 A+AAGI P MNPVLLKP+SD AQV++ GKV +M+A YH YK + +L Y L Sbjct: 63 AEAAGITPDVRMNPVLLKPTSDRQAQVVLMGKVATNMDAVSYHDYKPRLREQILAVYNSL 122 Query: 127 RAQYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDC 186 +Y +++EGAGSPAEINLR R I NMG AE CPVI+VADIDRGGVFA + GTL Sbjct: 123 AQEYDVIVLEGAGSPAEINLRDR-DIVNMGMAEMAQCPVILVADIDRGGVFAAIYGTLAL 181 Query: 187 LSESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGLHLDAEDAVA-A 245 L + ER RV G +IN+FRGD++LL +G++ +E TG PVL V+P+L + L+ ED VA Sbjct: 182 LHKQERDRVKGVIINKFRGDVALLYSGIEQIESLTGVPVLGVMPWLD-VDLEDEDGVALQ 240 Query: 246 TQEVKG----EFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPPADLIILPGSK 301 + +G + I + P ISN TDF+AL A P V +R+I + + DL+ILPGSK Sbjct: 241 NDKYRGNAPRDITIAIVQLPHISNFTDFNALAAQPDVRIRYIRRPEALTDVDLVILPGSK 300 Query: 302 NTRGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGL 361 NT DL WLRE G A+ + R G V+GICGG+QMLG+++ D VE G+ GLGL Sbjct: 301 NTLSDLAWLRESGMADAVLQTHRQGVPVMGICGGYQMLGDTIVDE--VESGLGTQPGLGL 358 Query: 362 LAMRTELTRDKRLLQVSGHCA-------VGDRSAPVRGYEIHMGVSSGAALERPAFVIEG 414 L T +DK QV+ + PVRGYEIHMG + A ++ Sbjct: 359 LNTITRFAQDKTTTQVNATMSGELPGWLAAAAGLPVRGYEIHMGETVLQEGCCTAMTLQK 418 Query: 415 RG----EGAQSADGQILGSYLHGMFDT 437 G +GA +ADG G+YLHG+FD+ Sbjct: 419 NGCSVADGAVTADGLAFGTYLHGLFDS 445 >SMc04309 [H] COG1492 Cobyric acid synthase Sme Sinorhizobium meliloti Length = 484 Score = 398 bits (1022), Expect = e-110, Method: Compositional matrix adjust. Identities = 221/471 (46%), Positives = 291/471 (61%), Gaps = 14/471 (2%) Query: 7 HTLMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQ 66 +M+QGT SD GKS L A LCRL G+SV PFKPQNM+ N+AV DGGEIGRAQ LQ Sbjct: 3 RKIMLQGTGSDVGKSVLVAGLCRLASNHGLSVKPFKPQNMSNNAAVADDGGEIGRAQWLQ 62 Query: 67 AQAAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARL 126 A AA + MNPVLLKP +D G+QV+V G+V ++Y K + +V++S+ ++ Sbjct: 63 ALAARVPSSVHMNPVLLKPQTDVGSQVVVQGRVAGQAKGKEYQALKPSLLGSVMESFEQV 122 Query: 127 RAQYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDC 186 A VIVEGAGSPAEINLRA IANMGFA D PV++V DIDRGGV A L GT Sbjct: 123 SAGADLVIVEGAGSPAEINLRA-GDIANMGFATRADVPVVLVGDIDRGGVIASLVGTHAI 181 Query: 187 LSESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGL-HLDAEDAVAA 245 L +R V G++IN+FRGD++L G+ + Q TG P V+P+L L AED+V Sbjct: 182 LPGDDRRMVTGYLINKFRGDVTLFDDGIASVRQFTGWPCFGVVPWLKSAGRLPAEDSVVL 241 Query: 246 TQEVKG---EFRIVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVP-PADLIILPGSK 301 + +G ++ VPV RI+N D D L A P VD+ F+ PG P+P A LI++PGSK Sbjct: 242 ERLTRGGGKALKVAVPVLSRIANFDDLDPLAAEPDVDIVFVRPGTPLPDDAGLIVIPGSK 301 Query: 302 NTRGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGL 361 +T DL R GW+ + RH+R GG+V+GICGG+QMLG V DP G+EG GLGL Sbjct: 302 STIADLDDFRRQGWDRDLDRHMRRGGRVVGICGGYQMLGSRVADPLGIEGGKREIEGLGL 361 Query: 362 LAMRTELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVIEGRGEGAQS 421 L++ TE+ +K + D + GYEIH+G ++GA R I+GR +GA S Sbjct: 362 LSVETEMAPEKTVRNSRAWSREYD--VALEGYEIHLGKTTGADCSRAPVEIDGRPDGAMS 419 Query: 422 ADGQILGSYLHGMFDTPQALGVLLDWAGLAGA-----EPVDLDALREVSLE 467 ADG+++G+YLHG+F + LL G+ G VD AL E++LE Sbjct: 420 ADGRVMGTYLHGLFGSDAYRSALLKSFGIEGGGGNYRRSVDA-ALDEIALE 469 >BMEI0690 [H] COG1492 Cobyric acid synthase Bme Brucella melitensis Length = 506 Score = 388 bits (996), Expect = e-107, Method: Compositional matrix adjust. Identities = 210/432 (48%), Positives = 279/432 (64%), Gaps = 8/432 (1%) Query: 9 LMIQGTTSDAGKSTLAAALCRLLKKDGVSVAPFKPQNMALNSAVTSDGGEIGRAQALQAQ 68 +M QGT SD GKS L A LCR+ + G+ V PFKPQNM+ N+AV+ DGGEIGRAQ LQA Sbjct: 28 IMFQGTGSDVGKSVLVAGLCRVARNRGLKVRPFKPQNMSNNAAVSDDGGEIGRAQWLQAL 87 Query: 69 AAGIAPHTDMNPVLLKPSSDTGAQVIVHGKVRADMNARDYHRYKTEAMQAVLQSYARLRA 128 A G+ MNPVLLKP +D G+Q+IV G+VR + R Y K + M AV++S+A++ Sbjct: 88 ACGVPSSVHMNPVLLKPQTDMGSQLIVQGQVRGEARGRYYQELKPQLMAAVMESFAKVGD 147 Query: 129 QYACVIVEGAGSPAEINLRARAHIANMGFAEAVDCPVIIVADIDRGGVFAHLTGTLDCLS 188 V+VEGAGSPAEINLRA IANMGFA D PV++V DIDRGGV A L GT L Sbjct: 148 GADLVLVEGAGSPAEINLRA-GDIANMGFATHADVPVVLVGDIDRGGVIASLVGTHTILP 206 Query: 189 ESERARVIGFVINRFRGDISLLQAGLDWLEQRTGKPVLAVLPYLHGL-HLDAEDAVAATQ 247 + +RA V GF+IN+FRGDISL L + + TG V+P+L + L AED+V + Sbjct: 207 QEDRAMVRGFLINKFRGDISLFDDSLAAITRFTGWRSFGVVPWLKAVSRLPAEDSVVLER 266 Query: 248 EVKGEFR---IVVPVFPRISNHTDFDALRAHPGVDLRFIGPGKPVPP-ADLIILPGSKNT 303 V+G+ + + VP+ PRI+N D D L+A P V++ + PG +P A L++LPG+K+T Sbjct: 267 AVRGDKKALIVAVPMLPRIANFDDLDPLKAEPAVEVVMVPPGSSLPADAGLVVLPGTKST 326 Query: 304 RGDLRWLREHGWEAAIARHLRYGGKVIGICGGFQMLGESVDDPHGVEGAPGSSAGLGLLA 363 DL LRE+GW+ + H++ GG V+GICGGFQMLG + DP G+EG GLGLL Sbjct: 327 IADLLALRENGWDRELVAHVKRGGHVLGICGGFQMLGRRISDPAGIEGNVRDIEGLGLLD 386 Query: 364 MRTELTRDKRLLQVSGHCAVGDRSAPVRGYEIHMGVSSGAALERPAFVIEGRGEGAQSAD 423 + T +K + V + D P+ GYEIH+G +SG + RP I +GA S D Sbjct: 387 IETMTEPEKVVRNVEAVSLLHDE--PLEGYEIHIGRTSGPDMARPFARIGDHDDGAVSPD 444 Query: 424 GQILGSYLHGMF 435 G+I+G+YLHG+F Sbjct: 445 GRIMGTYLHGVF 456