BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0056.p (1096 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0626 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 851 0.0 alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 523 e-148 Rv2062c [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 496 e-139 MT2121 [H] COG1429 Cobalamin biosynthesis protein CobN and relat... 496 e-139 PA2944 [H] COG1429 Cobalamin biosynthesis protein CobN and relat... 434 e-121 SMc04303 [H] COG1429 Cobalamin biosynthesis protein CobN and rel... 421 e-117 slr1211 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 416 e-115 MJ0908 [H] COG1429 Cobalamin biosynthesis protein CobN and relat... 416 e-115 VNG1566G [H] COG1429 Cobalamin biosynthesis protein CobN and rel... 401 e-111 BMEI0695 [H] COG1429 Cobalamin biosynthesis protein CobN and rel... 389 e-107 >RSp0626 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Rso Ralstonia solanacearum Length = 1379 Score = 851 bits (2198), Expect = 0.0, Method: Compositional matrix adjust. Identities = 428/663 (64%), Positives = 508/663 (76%), Gaps = 18/663 (2%) Query: 8 IALLTHAPTDLAMLATARAQLPADFPAVAGYDLQRLQAADQDQASQWPSLAALLRGELAA 67 I LLTHA TDL+ L A AQLP F V G LQ A D A +A LL G +A Sbjct: 9 IVLLTHAGTDLSTLQRATAQLPDGFAGVTGLHLQ----AIGDDA----RMADLLAGPIAG 60 Query: 68 AQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQQAL 127 A+++++RVLGRL A+ G +L RA+GR L+++SGTGEPDPELAA ST P +QQ+ Sbjct: 61 ARIVIVRVLGRLQAIPGIDALLHDTRAQGRALVIVSGTGEPDPELAARSTVPPALQQEVA 120 Query: 128 AYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLALRAQ 187 AY GG+ NLAQ+LRCLSDRLL++G+GY+P ALPEHG+YHP+L A + DW A+R Sbjct: 121 AYLQAGGTGNLAQLLRCLSDRLLMTGFGYQPPMALPEHGIYHPELAAPATLDDWAAIRNP 180 Query: 188 APAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQALPPA 247 A P VGI FYRAHWL GNT FID LV AL + L+ LPV+T+SLR G +P A Sbjct: 181 A---WPTVGIAFYRAHWLCGNTRFIDQLVDALAEQRLNALPVYTASLRTLDATG--MPAA 235 Query: 248 LQYF---GAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQAITSGMTQAQ 304 L F G G++D ++NTTSFAMG++ A G T AGWSV+ +LD+PV+QAI S MTQAQ Sbjct: 236 LDVFADDGVGRIDALVNTTSFAMGDVNADGPTAAGWSVAAFTRLDVPVVQAIASSMTQAQ 295 Query: 305 WQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAVQYQPLPDRVRRIAGLAQR 364 W S RG+NPLD AMNV LPEFDGRI+ VP+SFK+ D A Y PLPDRVRR+AG+ R Sbjct: 296 WAASERGLNPLDTAMNVALPEFDGRIVSVPMSFKDERDETA--YAPLPDRVRRVAGIVAR 353 Query: 365 LVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADGYAIDALPQT 424 V LR T A+KRIAF+FTNSSSKASQIGNAVGLD+P SL+ +LRA+ A GY ID LP++ Sbjct: 354 QVALRRTAPADKRIAFLFTNSSSKASQIGNAVGLDSPASLLTLLRAMQAQGYRIDGLPES 413 Query: 425 GTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQDKMQRQWGAAPG 484 G ALIH L+DR +YD+ L+ QL +A A +PAARYA WF+ LP LQDKM+++WG APG Sbjct: 414 GDALIHALIDRGAYDEDYLSAAQLEQAIATVPAARYAAWFSDLPAPLQDKMRQRWGDAPG 473 Query: 485 QAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEEWG 544 AYVHD LV AG++ GNAFVALQPPRGYGMDPDAIYH PDLPPTHHYYALYRWL +EW Sbjct: 474 NAYVHDGKLVFAGMEYGNAFVALQPPRGYGMDPDAIYHTPDLPPTHHYYALYRWLRDEWR 533 Query: 545 AHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIINDPGEGSQAKRRAHAV 604 A AIVHVGKHGTLEWLPGKGVG+S CFPDALLGD+PLFYPFI+NDPGEGSQAKRRAHAV Sbjct: 534 ADAIVHVGKHGTLEWLPGKGVGVSQTCFPDALLGDLPLFYPFILNDPGEGSQAKRRAHAV 593 Query: 605 VVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQIWELVRQTNLDTDLQ 664 ++DHLTPPMTTAD+YG LAQLTQLVDEYYQVE+LDP+KLPLLQQQIW+L+++ LD DL Sbjct: 594 IIDHLTPPMTTADTYGPLAQLTQLVDEYYQVEMLDPAKLPLLQQQIWDLIKEARLDADLA 653 Query: 665 YKL 667 L Sbjct: 654 AML 656 >alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Nos Nostoc sp. PCC 7120 Length = 1302 Score = 523 bits (1347), Expect = e-148, Method: Compositional matrix adjust. Identities = 331/858 (38%), Positives = 446/858 (51%), Gaps = 89/858 (10%) Query: 6 ARIALLTHAPTDLAMLATARAQLPADFPAVAGYDLQRLQAADQDQASQWPSLAALLRGEL 65 A L+T A TD+ LA A +LPA FPA+ +L LQ Q S+ L Sbjct: 25 APFVLITAADTDIQTLAAAVPKLPATFPAIRVANLLLLQ--------QQISIDTYAEQVL 76 Query: 66 AAAQVIVLRVLG-RLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 AQVI+LR+LG R G + +V G LIV+ G DPEL + STAP Sbjct: 77 ELAQVIILRLLGGRSYWAYGLEVVQEIVERTGITLIVMPGDDALDPELISQSTAPVGTVN 136 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYH----PDLEQDAGI-A 179 Q YF GG N+ L+ +SD L + Y Q +P GLY + + D G Sbjct: 137 QIWQYFYEGGVENIVNALQLISDVSLKTTYKPPAPQRVPRVGLYEWGMGTNRQGDKGNEV 196 Query: 180 DWLALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAG 239 ++ +Q+ P VGI+FYRAH+L+GN IDAL AAL R L +PVF SSLR Sbjct: 197 EFSPTSSQSLI--PKVGILFYRAHYLAGNIQVIDALCAALWQRNLQPVPVFISSLRDPDV 254 Query: 240 GGQALPPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQAITSG 299 + L Q + Q+ L++NTTSF++ + W E+LD+PVLQ I SG Sbjct: 255 QAE-LIDFFQPKDSQQISLLLNTTSFSLARLETEAPQTELW-----EKLDVPVLQVILSG 308 Query: 300 MTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETT------DSGAVQYQPLPD 353 QW+ G++P D AMNV LPE DGRII +SFK ++ V Y+P+ D Sbjct: 309 GFVEQWEAQLNGLSPRDIAMNVALPEVDGRIISRAVSFKAIQTRNPDLETDVVVYEPISD 368 Query: 354 RVRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSA 413 R+ +A LA V LRS P +RIA I N ++ ++ N VGLD PES + +L+AL Sbjct: 369 RIDFVAQLAANWVHLRSQPPQQRRIALILANYPNRDGRLANGVGLDTPESCVEILKALQQ 428 Query: 414 DGYAIDALPQTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQ- 472 GY + LP G LI L + D ++R + + Y ++FA LP ++Q Sbjct: 429 SGYVVSNLPANGDELIQLLTAGVTNDP---EGREIRPVQQSLSSEEYQEYFAGLPATVQQ 485 Query: 473 ---DKMQRQWGAAPGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPT 529 ++ R WG + I G+ GN FV +QP RGY +DP+ YH PDL PT Sbjct: 486 GINERWGRDWGLGEQASNFPSSSCPIPGIQFGNVFVGIQPSRGYDIDPNLNYHAPDLEPT 545 Query: 530 HHYYALYRWLDEEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIIN 589 H Y A Y W+ E +GA A+VHVGKHG LEWLPGK + LS C+P+A+ G MP YPFI+N Sbjct: 546 HAYLAFYYWVRESFGADAVVHVGKHGNLEWLPGKSLALSSNCYPEAVFGPMPHLYPFIVN 605 Query: 590 DPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQ 649 DPGEGSQAKRRA AV++DHLTPPMT A+ YGAL +L LVDEYY+ E LDPS+L +++ + Sbjct: 606 DPGEGSQAKRRAQAVIIDHLTPPMTRAELYGALQKLENLVDEYYEAESLDPSRLGVIRDR 665 Query: 650 IWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHAHHDHDHA 709 I +LV Q NL DL + D Sbjct: 666 IRDLVIQENLYKDL-------------------------------------GIEKEEDIV 688 Query: 710 HEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPDMLVAL 769 + E + ++L DGYLCEL AQIRDGLHI G+ P Q+ D++VA+ Sbjct: 689 NFESLILNSL---------------DGYLCELKEAQIRDGLHIFGQCPQGRQLRDLIVAI 733 Query: 770 TRLPNQDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDA--LARCADRPIVTRADALEAI 827 R+PN+ G+ +A ++GL D L ++ L+ D LA P T DA+ A+ Sbjct: 734 ARIPNRYSTGITRALANVWGLDFDPLTDNFSTPLSTQDQKLLAAKTPNPCRTVGDAVTAL 793 Query: 828 DALCLRLMQALQEHDFAP 845 + L++ L AP Sbjct: 794 EEHAALLVEQLINPPTAP 811 >Rv2062c [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Mtu Mycobacterium tuberculosis H37Rv Length = 1194 Score = 496 bits (1278), Expect = e-139, Method: Compositional matrix adjust. Identities = 324/835 (38%), Positives = 432/835 (51%), Gaps = 141/835 (16%) Query: 65 LAAAQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 LA A ++V+R+LG A Q + V A G +++SG D EL ST A Sbjct: 43 LAEASIVVIRILGGYRAWQ---SGIDTVIAGGVPAVLVSGEQAADAELTDRSTVAAGTAL 99 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLAL 184 QA Y GG NL ++ L D +L++G+G+ P A P G+ Sbjct: 100 QAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTPPVATPTWGVLE--------------- 144 Query: 185 RAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQAL 244 R A P + +++YRA L+GNT +++AL A+E G LP++ +SLR A Sbjct: 145 RPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRAIEDAGGRPLPLYCASLRT------AE 198 Query: 245 PPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAG---------WSVSVLEQLDLPVLQA 295 P L+ G D ++ T + AGGV PA W+V L LD+P+LQ Sbjct: 199 PRLLERLGGA--DAMVVTV------LAAGGVKPAAASAGGDDDSWNVEHLAALDIPILQG 250 Query: 296 ITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAVQYQPLPDRV 355 + + QW + G++PLD A V +PEFDGRII VP SFKE D G + Y P+R Sbjct: 251 LCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGRIITVPFSFKEIDDDGLISYVADPERC 310 Query: 356 RRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADG 415 R+AGLA R RLR A+KR+A +F+ +K ++IGNAVGLD P S +A+L+A+ G Sbjct: 311 ARVAGLAVRHARLRQVAPADKRVALVFSAYPTKHARIGNAVGLDTPASAVALLQAMRQRG 370 Query: 416 YAIDALP----QTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSL 471 Y + LP G ALIH L++ +D LTE QL R+ A Y WFA LP L Sbjct: 371 YRVGDLPGVESNDGDALIHALIECGGHDPDWLTEGQLAGNPIRVSAKEYRDWFATLPAEL 430 Query: 472 QDKMQRQWGAAPGQAYVHDQH-----LVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDL 526 D + WG PG+ +V H +VIA L GN + +QPPRG+G +P AIYH PDL Sbjct: 431 TDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRAGNLVLMVQPPRGFGENPVAIYHDPDL 490 Query: 527 PPTHHYYALYRWLD----EEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPL 582 PP+HHY A YRWLD +GAHA+VH+GKHG LEWLPGK +G+S C PDA LGD+PL Sbjct: 491 PPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGNLEWLPGKTLGMSASCGPDAALGDLPL 550 Query: 583 FYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSK 642 YPF++NDPGEG+QAKRRAHAV+VDHL PPM A++YG +A+L QL+DE+ V LDP K Sbjct: 551 IYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHASVAALDPGK 610 Query: 643 LPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHA 702 LP ++QQIW L+R +D DL Sbjct: 611 LPAIRQQIWTLIRAAKMDHDLGLT------------------------------------ 634 Query: 703 HHDHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQM 762 EE L +DG +LCE+ QIRDGLHILG+ P Q Sbjct: 635 -----ERPEEDSFDDMLLHVDG------------WLCEIKDVQIRDGLHILGQNPTGEQE 677 Query: 763 PDMLVALTRLPN-----QDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDALARCADRPI 817 D+++A+ R +PGL++ GL+ D E R +D Sbjct: 678 LDLVLAILRARQLFGGAHAIPGLRQA----LGLAEDGTDE----RATVDQ---------- 719 Query: 818 VTRADALEAIDALCLRLMQALQEHDFAPTAIDGVLGSVFAA--LEQASPEQRPRL 870 T A A E L+ ALQ + P+A D + G+ AA L A+ E PRL Sbjct: 720 -TEAKARE--------LVAALQATGWDPSAADRLTGNADAAAVLRFAATEVIPRL 765 >MT2121 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases MtC Mycobacterium tuberculosis CDC1551 Length = 1195 Score = 496 bits (1278), Expect = e-139, Method: Compositional matrix adjust. Identities = 324/835 (38%), Positives = 432/835 (51%), Gaps = 141/835 (16%) Query: 65 LAAAQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 LA A ++V+R+LG A Q + V A G +++SG D EL ST A Sbjct: 44 LAEASIVVIRILGGYRAWQ---SGIDTVIAGGVPAVLVSGEQAADAELTDRSTVAAGTAL 100 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLAL 184 QA Y GG NL ++ L D +L++G+G+ P A P G+ Sbjct: 101 QAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTPPVATPTWGVLE--------------- 145 Query: 185 RAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQAL 244 R A P + +++YRA L+GNT +++AL A+E G LP++ +SLR A Sbjct: 146 RPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRAIEDAGGRPLPLYCASLRT------AE 199 Query: 245 PPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAG---------WSVSVLEQLDLPVLQA 295 P L+ G D ++ T + AGGV PA W+V L LD+P+LQ Sbjct: 200 PRLLERLGGA--DAMVVTV------LAAGGVKPAAASAGGDDDSWNVEHLAALDIPILQG 251 Query: 296 ITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAVQYQPLPDRV 355 + + QW + G++PLD A V +PEFDGRII VP SFKE D G + Y P+R Sbjct: 252 LCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGRIITVPFSFKEIDDDGLISYVADPERC 311 Query: 356 RRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADG 415 R+AGLA R RLR A+KR+A +F+ +K ++IGNAVGLD P S +A+L+A+ G Sbjct: 312 ARVAGLAVRHARLRQVAPADKRVALVFSAYPTKHARIGNAVGLDTPASAVALLQAMRQRG 371 Query: 416 YAIDALP----QTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSL 471 Y + LP G ALIH L++ +D LTE QL R+ A Y WFA LP L Sbjct: 372 YRVGDLPGVESNDGDALIHALIECGGHDPDWLTEGQLAGNPIRVSAKEYRDWFATLPAEL 431 Query: 472 QDKMQRQWGAAPGQAYVHDQH-----LVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDL 526 D + WG PG+ +V H +VIA L GN + +QPPRG+G +P AIYH PDL Sbjct: 432 TDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRAGNLVLMVQPPRGFGENPVAIYHDPDL 491 Query: 527 PPTHHYYALYRWLD----EEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPL 582 PP+HHY A YRWLD +GAHA+VH+GKHG LEWLPGK +G+S C PDA LGD+PL Sbjct: 492 PPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGNLEWLPGKTLGMSASCGPDAALGDLPL 551 Query: 583 FYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSK 642 YPF++NDPGEG+QAKRRAHAV+VDHL PPM A++YG +A+L QL+DE+ V LDP K Sbjct: 552 IYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARAETYGDIARLEQLLDEHASVAALDPGK 611 Query: 643 LPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHA 702 LP ++QQIW L+R +D DL Sbjct: 612 LPAIRQQIWTLIRAAKMDHDLGLT------------------------------------ 635 Query: 703 HHDHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQM 762 EE L +DG +LCE+ QIRDGLHILG+ P Q Sbjct: 636 -----ERPEEDSFDDMLLHVDG------------WLCEIKDVQIRDGLHILGQNPTGEQE 678 Query: 763 PDMLVALTRLPN-----QDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDALARCADRPI 817 D+++A+ R +PGL++ GL+ D E R +D Sbjct: 679 LDLVLAILRARQLFGGAHAIPGLRQA----LGLAEDGTDE----RATVDQ---------- 720 Query: 818 VTRADALEAIDALCLRLMQALQEHDFAPTAIDGVLGSVFAA--LEQASPEQRPRL 870 T A A E L+ ALQ + P+A D + G+ AA L A+ E PRL Sbjct: 721 -TEAKARE--------LVAALQATGWDPSAADRLTGNADAAAVLRFAATEVIPRL 766 >PA2944 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Pae Pseudomonas aeruginosa Length = 1248 Score = 434 bits (1115), Expect = e-121, Method: Compositional matrix adjust. Identities = 266/676 (39%), Positives = 363/676 (53%), Gaps = 43/676 (6%) Query: 8 IALLTHAPTDLAMLATARAQL----------PADFPAVAGYDLQRLQAADQDQASQWPSL 57 IA L P +L +L + + L P D+P+ L+ A+ Q S+ Sbjct: 17 IAHLAQTPAELVILCSGDSHLALLAEAARALPDDYPS--------LRLANPMQLQNHASV 68 Query: 58 AALLRGELAAAQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAAST 117 + L A+VI+L + G +G + E L + G LI + G PDPEL+A Sbjct: 69 DLYVEEVLRHARVILLSLHGGIGYWRYGVEQLVALAERGALLIPVPGDDRPDPELSALGN 128 Query: 118 APADVQQQALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAG 177 PA+ ++ Y GG N Q RCL+ + L Y + QALP L+HP +A Sbjct: 129 LPAEQAERFWQYLRQGGLENAGQFYRCLASQCLGRDYAWREPQALPRVALFHPR-HAEAT 187 Query: 178 IADWLALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVS 237 + W RA AG+P V ++FYR H + NTAFI L A+GL+ LP+ +SL+ S Sbjct: 188 LEHW---RADWQAGRPVVALLFYRTHLQAANTAFIARFCERLAAQGLNPLPIALASLKES 244 Query: 238 AGGGQALPPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQAIT 297 A L + LI+NTT FA A + P + D+PVLQAI Sbjct: 245 A----CLAQVEDWLERSDAALIVNTTGFAQSNPEAPELRPF--------RRDVPVLQAIC 292 Query: 298 SGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFK------ETTDSGAVQYQPL 351 S + W + +G+ P D AM+V LPE DGRI+ P+SFK E ++S V Y Sbjct: 293 SLDNRPLWLDNPQGLGPRDLAMHVALPELDGRIVTRPISFKGLAWRSERSESDVVCYLAD 352 Query: 352 PDRVRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRAL 411 +R+ +A LA+R L PNA KR+A + N ++ +IGN VGLD P + + +LRAL Sbjct: 353 DERMDFVAELARRWAELARKPNAEKRVALVLANYPTRDGRIGNGVGLDTPAAALNILRAL 412 Query: 412 SADGYAIDALPQTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSL 471 GY +D LP +GT LI +L+ S D L LR A + Y FA LP Sbjct: 413 RQQGYPVDGLPASGTELIRQLLGGVSND---LEHLDLRPCAQSLALDDYLACFARLPERN 469 Query: 472 QDKMQRQWGAAPGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHH 531 + + +WG D +++AGL G FV +QP RGY +DP A+YH PDL P H Sbjct: 470 RQAVLARWGEPQQDPMFRDGRMMVAGLRYGLTFVGIQPARGYQLDPAAVYHDPDLVPPHG 529 Query: 532 YYALYRWLDEEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIINDP 591 Y A Y WL + A A++HVGKHG LEWLPGKGVGLS EC+PDALLG +P YPFI+NDP Sbjct: 530 YLAFYFWLRHAYRADALLHVGKHGNLEWLPGKGVGLSAECWPDALLGPLPNIYPFIVNDP 589 Query: 592 GEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQIW 651 GEG+QAKRR AV++DHL PP+T A+SYG L L +L DE+Y +LDP + L+ +I Sbjct: 590 GEGAQAKRRTQAVIIDHLMPPLTRAESYGPLRDLERLADEFYDASLLDPRRAEQLRGEIL 649 Query: 652 ELVRQTNLDTDLQYKL 667 L+R LD ++ +L Sbjct: 650 VLLRDNRLDREIGLQL 665 >SMc04303 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Sme Sinorhizobium meliloti Length = 1275 Score = 421 bits (1082), Expect = e-117, Method: Compositional matrix adjust. Identities = 304/881 (34%), Positives = 426/881 (48%), Gaps = 132/881 (14%) Query: 68 AQVIVLRVLGRLGAVQGFPEMLRVVRAEGR-QLIVLSGTGEPDPELAAASTAPADVQQQA 126 A++IV+R LG + E L + Q+ VL G +PDP L ST + +Q+ Sbjct: 78 AKLIVVRPLGGASYFRYVLEALYAAAVANKFQIAVLPGDDKPDPGLDPFSTVSVEDRQRL 137 Query: 127 LAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWL---A 183 Y GG+ N A + + L+ G +PA+ L + G++ P G+ +W+ Sbjct: 138 WGYCTEGGAEN-AGLFLDYAQALIDGGDKPQPARPLLKAGIWWPG-RGVIGVEEWVRLSE 195 Query: 184 LRAQAPAG-------KPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLR- 235 LR P +P V + FYRA SG T ++AL+ AL A G+ LPVF SSL+ Sbjct: 196 LRRAVPTAQADRAEHEPTVAVCFYRALVQSGETKPVEALIEALAAEGVRALPVFVSSLKD 255 Query: 236 -VSAGGGQALPPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQ 294 VS G +A+ F D+++N T FA ++A G A +VLE PVLQ Sbjct: 256 PVSIGTLEAV------FAEALPDVVMNATGFA---VSAPG---ADRQPTVLESGGAPVLQ 303 Query: 295 AITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETT------DSGAVQY 348 I SG ++ W+ S +G+ D MNV LPE DGR++ +SFK + ++ V + Sbjct: 304 VIFSGSSREGWETSAQGLMARDLGMNVALPEVDGRVLSRAVSFKAASVYDPLVEANIVGH 363 Query: 349 QPLPDRVRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVL 408 +PL DR R A LA +LR T +R+A + N ++ ++GN VGLD P + VL Sbjct: 364 EPLTDRARFAARLAANWTKLRRTRPEGRRVAIVMANYPNRDGRLGNGVGLDTPAGTIEVL 423 Query: 409 RALSADGYAIDALPQTGTALIHELV----DRCSYDDILLTEDQLRRAAARIPAARYAQWF 464 +A++A+GYA+ +P G ALI L+ + S D R I RY +F Sbjct: 424 KAMTAEGYAVGNVPDDGDALIGFLMAGPTNAASRD---------REIRETISLNRYKGFF 474 Query: 465 AALPTSLQDKMQRQWGAAPGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQP 524 ALP +Q+++ +WGAA + D + G+ V +QP RGY +DP YH P Sbjct: 475 DALPKKIQEEVTARWGAAEADPFFIDGVFALPLARFGDVLVGIQPARGYNIDPKETYHAP 534 Query: 525 DLPPTHHYYALYRWLDEEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFY 584 DL P H Y A Y +L E +GAHAIVH+GKHG LEWLPGK + LS+EC+P+ + G MP Y Sbjct: 535 DLVPPHGYLAFYAYLREVFGAHAIVHMGKHGNLEWLPGKALALSEECYPEVIFGPMPHLY 594 Query: 585 PFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLP 644 PFI+NDPGEG+QAKRR AV++DHLTPP+T A+SYG L L LVDEYY+ DP +L Sbjct: 595 PFIVNDPGEGTQAKRRTSAVIIDHLTPPLTRAESYGPLKDLEALVDEYYEAAGGDPRRLR 654 Query: 645 LLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHAHH 704 LL +QI +LVR LD Sbjct: 655 LLSRQILDLVRDIGLD-------------------------------------------- 670 Query: 705 DHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPD 764 HD E+G+ + +E LD YLC+L QIRDGLH+ G P+ + D Sbjct: 671 -HDAGIEKGDSEN-----------RALEKLDAYLCDLKEMQIRDGLHVFGLAPEGRLLTD 718 Query: 765 MLVALTRLPNQDLPG----LQEEVARLFGL-------------SLDMLLEHKGRRLNIDD 807 + VAL R+P G LQ +A GL LD ++ L D Sbjct: 719 LTVALARVPRGLGEGGDQSLQRAIAVDLGLHAASRSQRPQPFDPLDCVMSDPWAGLK-PD 777 Query: 808 ALARCADRPIVTRADALEAIDALCLRLMQALQEHDFAPTAIDGVLGSVFAALEQASPEQR 867 LA +D P T D +E I+ L +L+ T VL + L + Sbjct: 778 LLAALSDAPWRTAGDTVERIELLAAKLVSGEIACPVGWTNTRAVLAVIETRL-------K 830 Query: 868 PRLQPAMSQAATSVLGGMRAKERVPGSTRAAPCGACQRAKP 908 P +Q + +L G+ + PG P GA R +P Sbjct: 831 PSIQSSGEAEIKGLLTGLDGRFVAPG-----PSGAPTRGRP 866 >slr1211 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Syn Synechocystis Length = 1092 Score = 416 bits (1069), Expect = e-115, Method: Compositional matrix adjust. Identities = 243/615 (39%), Positives = 331/615 (53%), Gaps = 78/615 (12%) Query: 194 AVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLR---VSAGGGQALPPALQY 250 + IIFYR+H+LSGNT IDAL ALE L+ L ++ SSLR V A L Q Sbjct: 9 TIAIIFYRSHYLSGNTTPIDALCQALEKHNLNPLAIYVSSLREPDVQAEILAILENLDQP 68 Query: 251 FGAGQVDLIINTTSFAMGEIT--AGGVTPAGWSVSVLEQLDLPVLQAITSGMTQAQWQHS 308 GA I+NTTSF++ ++ G + + + ++L++PVLQ I SG + QWQ Sbjct: 69 LGA-----ILNTTSFSLAKLQRQIGNLE----MIPLWQKLNVPVLQVILSGGDRQQWQEG 119 Query: 309 TRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETT------DSGAVQYQPLPDRVRRIAGLA 362 RG+NP D AMNV LPE DGRII +SFK ++ Y+P+ DRV IA L Sbjct: 120 LRGLNPRDLAMNVALPEVDGRIITRAISFKAMAARHPQLETEVAIYEPVLDRVEWIAELT 179 Query: 363 QRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSADGYAIDALP 422 + ++ T ++IA I N +K ++ N VGLD P S + +L AL GY + A+P Sbjct: 180 KNIINCAQTEIFQRKIALILANYPNKDGRLANGVGLDTPASCLQILEALKIAGYHLSAIP 239 Query: 423 QTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQDKMQRQWGAA 482 + LI +L + D L Q R I + Q+F +LP S+Q M +W Sbjct: 240 KDTETLIKQLTQGVTNDQELA---QYRTVNQTIVTEKVWQFFYSLPQSVQQAMTERWQVR 296 Query: 483 PGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEE 542 + DQ I+G+ GN FV +QP RGY DP YH PDL PT HY A Y WL +E Sbjct: 297 ENWDNLPDQ-FAISGIQFGNIFVGIQPARGYDFDPSLNYHAPDLEPTLHYLAFYLWLRQE 355 Query: 543 WGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIINDPGEGSQAKRRAH 602 + A AI+H+GKHG LEWLPGK V LSD C P+ LG +P FYPFI+NDPGEG+QAKRR+ Sbjct: 356 FSAQAIIHLGKHGNLEWLPGKSVVLSDHCHPEIALGPLPNFYPFIVNDPGEGTQAKRRSQ 415 Query: 603 AVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLPLLQQQIWELVRQTNLDTD 662 A ++DHLTPP+T A+ YG L +L L+DEYY+ + LDP+++ + ++ +L+ +NL TD Sbjct: 416 ACIIDHLTPPLTRAELYGDLEKLEALIDEYYEAQALDPTRVKTIGDRLRKLLATSNLQTD 475 Query: 663 LQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHAHHDHDHAHEEGELPHALTEL 722 L G P AL +L Sbjct: 476 L-------------------------------------------------GLTPPALKDL 486 Query: 723 DGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPDMLVALTRLPNQDLPGLQE 782 L+ D YLCEL AQIRDGLHILG+TP Q+ D+ +++ R P+ GL + Sbjct: 487 QP-----LLTSADSYLCELKEAQIRDGLHILGQTPTGEQLRDLAISIARSPSYQRLGLTQ 541 Query: 783 EVARLFGLSLDMLLE 797 +A L D +L+ Sbjct: 542 AIAFDLELEFDPVLD 556 >MJ0908 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Mja Methanococcus jannaschii Length = 1232 Score = 416 bits (1068), Expect = e-115, Method: Compositional matrix adjust. Identities = 200/580 (34%), Positives = 328/580 (56%), Gaps = 14/580 (2%) Query: 65 LAAAQVIVLRVLGRLGAVQGFPEMLRVVRAEGRQLIVLSGTGEPDPELAAASTAPADVQQ 124 + A ++ +++G A + + E+ + + L E P+L T DV+ Sbjct: 54 IKEANIVFTKLMGGKNAFKYYDELAEFCKRHNIPFLPLPTISEIHPDLEKDRTVDDDVKN 113 Query: 125 QALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDAGIADWLAL 184 + + Y G N +L L++R YE + +P G+Y+ + + D+L Sbjct: 114 KVVKYLGYEGVYNYKNLLLYLANRFGNLNVEYEEPRPMPWQGIYYKG-KYFETLDDYLNY 172 Query: 185 RAQA--PAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLRVSAGGGQ 242 + KP +G++FYR +++ N +++ L+ +E +G + VF+S L+ G Sbjct: 173 LKELGRDLDKPIIGVLFYRNWFVANNIDYVNDLIDIIENKGAIPIAVFSSHLKNELGSIG 232 Query: 243 ALPPALQYF---GAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQAITSG 299 L ++F G V +INTT F + + L++L++P+LQ I S Sbjct: 233 TLETFKRFFYKDGKPIVHALINTTMFTLSMGVKAELLKD--EPEFLKELNVPILQGIIST 290 Query: 300 MTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKETTDSGAV-----QYQPLPDR 354 W+ S G+NP+D + + +PEFDG II P+ KE G V +Y+ + DR Sbjct: 291 GFIEDWKKSVSGLNPIDLIIGMAMPEFDGAIIHFPIGGKEKIKDGEVGVPIIKYRAIRDR 350 Query: 355 VRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLRALSAD 414 +I LA R L+ N +K+IA IF N + +I +A GLD+PES++ +L+ + Sbjct: 351 AEKIVDLALRYANLKLKSNKDKKIAIIFHNYPPRNDKIASAFGLDSPESVVNILKEMKKR 410 Query: 415 GYAIDALPQTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPTSLQDK 474 G+ +D +P+ GT LI ++++ + D LTE+ +++A ++ Y +WF +L ++ + Sbjct: 411 GFIVDEIPKNGTELIKKMLNYATNDKRFLTEEMIKKAVGKVKKEDYEKWFNSLSEKVKQE 470 Query: 475 MQRQWGAAPGQAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYA 534 + + WGA PG D L+I G+ GN F+++QPPRG+G +P AIYH PDLPPTH+Y A Sbjct: 471 LIKNWGAIPGDVMNFDGELIIPGIINGNVFISVQPPRGFGENPSAIYHSPDLPPTHYYIA 530 Query: 535 LYRWLDEEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFYPFIINDPGEG 594 Y+W+ + + A AI+H+GKHG LEWLPGK VGLS+EC+PD + ++P YPFI+N+PGEG Sbjct: 531 FYKWIKDVFKADAIMHIGKHGNLEWLPGKCVGLSNECYPDICM-ELPNIYPFIVNNPGEG 589 Query: 595 SQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQ 634 +QAKRR++A ++ HL PPMT +D YG L +L + +D+YY+ Sbjct: 590 TQAKRRSYATIISHLIPPMTISDLYGDLVELEKSIDDYYE 629 >VNG1566G [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Hbs Halobacterium sp. NRC-1 Length = 1234 Score = 401 bits (1030), Expect = e-111, Method: Compositional matrix adjust. Identities = 274/823 (33%), Positives = 403/823 (48%), Gaps = 77/823 (9%) Query: 100 IVLSGTGEPDPELAAASTAPADVQQQALAYFNGGGSVNLAQMLRCLSDRLLLSGYGYEPA 159 +V+ TG D +T A+ + Y + GGS N+A LR L DR + + Y+ Sbjct: 18 LVVKSTG--DAYAVEDTTVAAEDRDTVYEYLDRGGSANVANCLRFLGDRYSGTEFAYDDP 75 Query: 160 QALPEHGLYHPDLEQDAGIADWLALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAAL 219 ALP G+YHPD GI D+ LRA P V + FY +HW NT ++D +V AL Sbjct: 76 VALPTEGVYHPD---HPGI-DYDGLRATFDPDAPTVAVWFYESHWTHENTRYVDGVVHAL 131 Query: 220 EARGLDVLPVFTSSLRVSAGGGQALPPALQYF---GAGQVDLIINTTSFAMGEITAG-GV 275 E++G + LPVF + + A Q+ G VD ++++ F++ G Sbjct: 132 ESQGANALPVFCNPATDTDEQEDAEWVTDQWLLADGEPVVDAVVSSFMFSLSMDERGRSA 191 Query: 276 TPAGWSVS--VLEQLDLPVLQAITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGV 333 + G + L++L +PVLQ +T+ ++++++ + G+ + A++V LPEFDG +I Sbjct: 192 SDEGDAAEDVFLDRLGVPVLQTVTTMRSRSRYESADTGVMGFELALSVALPEFDGNVITH 251 Query: 334 PLSFKETTDSGA------VQYQPLPDRVRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSS 387 P+S KE TD A Q+ P+ DRV A LA RLR N KR+A + N Sbjct: 252 PISGKERTDDDAGIGTAPKQHFPIADRVEHAASLAVNWARLRHLDNDEKRVAVVLHNYPP 311 Query: 388 KASQIGNAVGLDAPESLMAVLRALSADGYAIDA-LPQTGTALIHELVDRCSYDDILLT-E 445 IG A GLD PES + +L L A GY++ P G ALI +L + + DD + E Sbjct: 312 SDDGIGTAFGLDTPESTVNLLDELDARGYSLGGKTPPEGQALIEQLTSQLTLDDRWVAPE 371 Query: 446 DQLRRAAARIPAARYAQWFAALPTSLQDKMQRQWGAAPGQAYVHDQHLVIAGLDLGNAFV 505 D R+ + YA W+A + + +WG P + + I G++ GN V Sbjct: 372 DVRERSVDVVSTDEYAAWWADTDPEFRANVVAEWGEPPERPFA------IPGVEYGNVLV 425 Query: 506 ALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEEWGAHAIVHVGKHGTLEWLPGKGV 565 +QPPRG+GMDP+ +YH DL P H YYA Y WL EE+GA A+VH+G HG+LEWLPGK V Sbjct: 426 TVQPPRGFGMDPEKVYHDSDLQPPHDYYAFYAWLREEFGADAVVHLGTHGSLEWLPGKTV 485 Query: 566 GLSDECFPDALLGDMPLFYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQL 625 GL E PDALLGD+P YP+I+N+PGEG+QAKRR++A VVD+LTP M+ A +Y LA+L Sbjct: 486 GLDAESAPDALLGDLPNVYPYIVNNPGEGTQAKRRSYAAVVDYLTPVMSNAGTYDELAEL 545 Query: 626 TQLVDEYYQVEVLDPSKLPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHH 685 +L Y + + I + +R+ D DL +L Sbjct: 546 EELASRYREAGA---GAGADAESHIADRIREQVADLDLAVEL------------------ 584 Query: 686 HHHHGHAHHHHDHGDHAHHDHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQ 745 G + D D + L + D G+ L+E + Y+ ++ Q Sbjct: 585 ----GIEGEISEKADVRGPDAAGSS----LAEGAVDGDTVGIEALVERVHEYVTDVKTTQ 636 Query: 746 IRDGLHILGRTPDQAQMPDMLVALTRLPNQDLPGLQEEVARLFGLSLDMLLEHKGRRLNI 805 IR GLH +G P ++ + LVALTRL N P L+E VA + G+ +L+ G Sbjct: 637 IRLGLHTMGEPPADDRLVEYLVALTRLENPGAPSLRESVAGVLGVDYGTMLDSPGE---Y 693 Query: 806 DDALARCADRPIVTRADALEAIDALCLRLMQALQEHDFAPTAIDGVLGSVFAALEQASPE 865 +AL +T A+A + + + L++ L F V A+ A P+ Sbjct: 694 SEALG-------MTYAEAADEVYETSVDLVETLAAEGF----------DVPASNVAAGPD 736 Query: 866 QRPRLQPAMSQAATSVLGGMRAKERVPGSTRAAPCGACQRAKP 908 + + T +G RAK RA C+ A P Sbjct: 737 DEVNMNLLVVDIDT--IGDARAKSGAHDDLRAVLAFICEEAAP 777 >BMEI0695 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Bme Brucella melitensis Length = 1263 Score = 389 bits (1000), Expect = e-107, Method: Compositional matrix adjust. Identities = 278/789 (35%), Positives = 386/789 (48%), Gaps = 119/789 (15%) Query: 7 RIALLTHAPTDLAMLATARAQLPADFPAVAGYDLQRLQAADQDQASQWPSLAALLRGELA 66 I L+ A T+LA +A A P D+ L+ A+ + S+ A + Sbjct: 26 EIVFLSAADTELASIAQAHRLAP---------DMPSLRLANFLGLTHPMSVDAYVERTAR 76 Query: 67 AAQVIVLRVLGRLGAVQGFPEMLRVVRA----EGRQLIVLSGTGEPDPELAAASTAPADV 122 A++IV+R++G +P L + A G ++ VL G +PD L ST PA Sbjct: 77 HAKLIVVRIIG---GETYWPYGLEALHACAITHGAKMAVLPGDDKPDHGLDRFSTIPAGE 133 Query: 123 QQQALAYFNGGGSVNLAQMLRCLSDRLLLSGYGY-EPAQALPEHGLYHPDLEQDAGIADW 181 + Y G+ N L + L+SG E A L + GL+ P E + + Sbjct: 134 RDDLWHYLIESGAANTHGFLAYC--KALISGCEKPEAAAPLLKAGLWWPG-EAVSSLTS- 189 Query: 182 LALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGLDVLPVFTSSLR------ 235 R A P II YRA SG T +DAL+AAL+ARGL+ LP+F SSL+ Sbjct: 190 -VQRHWADPAAPVAAIILYRALVQSGQTQPVDALIAALQARGLNPLPIFVSSLKDPLSAA 248 Query: 236 VSAGGGQALPPALQYFGAGQVDLIINTTSFAMGEITAGGVTPAGWSVSVLEQLDLPVLQA 295 V G + PP D+++N T FA I++ G A +VL++ VLQ Sbjct: 249 VVDGLFEDCPP----------DIVLNATGFA---ISSPG---AERKPTVLDKRGNMVLQV 292 Query: 296 ITSGMTQAQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKE------TTDSGAVQYQ 349 I SG + W+ S +G+ D AMNV LPE DGR++ +SFK + ++ V ++ Sbjct: 293 IFSGTPKTVWEASQQGLLARDLAMNVALPEVDGRVLSRAVSFKSAQQFDASVEANIVTHE 352 Query: 350 PLPDRVRRIAGLAQRLVRLRSTPNANKRIAFIFTNSSSKASQIGNAVGLDAPESLMAVLR 409 P PDRV +A LA VRL+ P A +R+A I N ++ ++GN VGLD P + VLR Sbjct: 353 PHPDRVAFVAELAANWVRLKRKPPAERRVALILANYPNRDGRLGNGVGLDTPAGTVEVLR 412 Query: 410 ALSADGYAIDALPQTGTALIHELV---DRCSYDDILLTEDQLRRAAARIPAARYAQWFAA 466 A++A+GY + +P AL+ L+ + D R I +Y F Sbjct: 413 AMAAEGYRVGEIPADSDALMRALMAGPTNAARDG--------REIRETISLNQYKALFGK 464 Query: 467 LPTSLQDKMQRQWGAAPGQAYVHDQ--HLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQP 524 L ++Q +++ +WGA Y + + + G FV +QP RGY +DP YH Sbjct: 465 LALTIQAEVEARWGAPENDPYFARELDAFALPLMRFGETFVGIQPARGYNIDPKETYHSL 524 Query: 525 DLPPTHHYYALYRWLDEEWGAHAIVHVGKHGTLEWLPGKGVGLSDECFPDALLGDMPLFY 584 DL P H Y A Y +L G A+VH+GKHG LEWLPGK + LS C+P+A+ G MP Y Sbjct: 525 DLVPPHGYIAYYAYLRAVAGVDAVVHMGKHGNLEWLPGKALALSQNCYPEAVFGPMPHIY 584 Query: 585 PFIINDPGEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPSKLP 644 PFI+NDPGEG+QAKRRA AV++DHLTPP+T A+SYG L L LVDEYY+ +DP +L Sbjct: 585 PFIVNDPGEGTQAKRRASAVIIDHLTPPLTRAESYGPLKDLEALVDEYYEASGVDPRRLL 644 Query: 645 LLQQQIWELVRQTNLDTDLQYKLLHHDHDHDHDHGHDHDHHHHHHGHAHHHHDHGDHAHH 704 L+ QI +LVR LD D G H H Sbjct: 645 RLKAQILDLVRDIGLD-----------------------------------RDAGIHDHD 669 Query: 705 DHDHAHEEGELPHALTELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRTPDQAQMPD 764 D D A ++ LD YLC+L QIRDGLH+ G P + D Sbjct: 670 DEDMA---------------------LQKLDAYLCDLKEMQIRDGLHVFGLAPQARLLTD 708 Query: 765 MLVALTRLP 773 +LVAL R+P Sbjct: 709 LLVALARVP 717