BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0126.p (395 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3140 [O] COG0265 Trypsin-like serine proteases, typically per... 194 2e-49 YPO3382 [O] COG0265 Trypsin-like serine proteases, typically per... 92 2e-18 htrA [O] COG0265 Trypsin-like serine proteases, typically peripl... 92 3e-18 ZhtrA [O] COG0265 Trypsin-like serine proteases, typically perip... 92 3e-18 ECs0165 [O] COG0265 Trypsin-like serine proteases, typically per... 92 3e-18 >RSc3140 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Rso Ralstonia solanacearum Length = 305 Score = 194 bits (494), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 94/185 (50%), Positives = 127/185 (68%) Query: 24 ALDAETLFQQLSPSIWVVQAMDAQGQIFSTGSAVVIGPERLVTNCHVLARASSFKLRRGN 83 AL+ +F+++SPS+W V+ + G+ S GSAVVIG ++TNCHVL L+RGN Sbjct: 2 ALEPAEIFEKVSPSVWEVRVIGPDGKGLSMGSAVVIGDGVVITNCHVLRGGKQVWLKRGN 61 Query: 84 LTLGGKLEFPDPERDLCQVRAEGLKAPAVTIAPARSLRVGQKVFTLGAPRALEETISDGL 143 G +L++PD ERDLCQ+R P VT+AP +L GQKV+ +G P LE TIS+GL Sbjct: 62 ANFGARLQYPDVERDLCQLRVADFHYPPVTLAPGSALVTGQKVYAIGNPLGLELTISEGL 121 Query: 144 LSALRLDNEGRLRFLQTSAPISSGSSGGGLFNDKGELIGITTAMIAGATVQNLSFAVPAE 203 +S+LR D++GRL+ +QTSA IS GSSGGGLF+ G LIGIT + QNL+FA+PA+ Sbjct: 122 ISSLRTDDDGRLKSVQTSAAISRGSSGGGLFDANGRLIGITDHQVVLTLGQNLNFAIPAD 181 Query: 204 WIRDL 208 WI D+ Sbjct: 182 WIADV 186 >YPO3382 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Ype Yersinia pestis Length = 481 Score = 92.0 bits (227), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 64/170 (37%), Positives = 96/170 (56%), Gaps = 12/170 (7%) Query: 52 STGSAVVI--GPERLVTNCHVLARAS--SFKLRRGNLTLGGKLEFPDPERDLCQVRAEGL 107 S GS V+I G +VTN HV+ A+ S KL G + K+ DP D+ ++ + Sbjct: 117 SLGSGVIIDAGKGYVVTNNHVVDNANKISVKLSDGR-SFDAKVIGKDPRTDIALLQLKDA 175 Query: 108 KA-PAVTIAPARSLRVGQKVFTLGAPRALEETISDGLLSALR---LDNEGRLRFLQTSAP 163 K A+ IA + LRVG +G P L ET++ G++SAL L+ E F+QT A Sbjct: 176 KNLTAIKIANSDQLRVGDYTVAIGNPYGLGETVTSGIVSALGRSGLNVENYENFIQTDAA 235 Query: 164 ISSGSSGGGLFNDKGELIGITTAMIA--GATVQNLSFAVPAEWIRDLETR 211 I+ G+SGG L N GELIGI TA++A G + + FA+P+ +++L ++ Sbjct: 236 INRGNSGGALINLNGELIGINTAILAPDGGNI-GIGFAIPSNMVKNLTSQ 284 >htrA [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Eco Escherichia coli K12 Length = 474 Score = 91.7 bits (226), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 58/172 (33%), Positives = 98/172 (56%), Gaps = 10/172 (5%) Query: 49 QIFSTGSAVVIGPER--LVTNCHVLARASSFKLRRGN-LTLGGKLEFPDPERDLCQVRAE 105 + + GS V+I ++ +VTN HV+ A+ K++ + K+ DP D+ ++ + Sbjct: 109 KFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQ 168 Query: 106 GLKA-PAVTIAPARSLRVGQKVFTLGAPRALEETISDGLLSALR---LDNEGRLRFLQTS 161 K A+ +A + +LRVG +G P L ET++ G++SAL L+ E F+QT Sbjct: 169 NPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTD 228 Query: 162 APISSGSSGGGLFNDKGELIGITTAMIA--GATVQNLSFAVPAEWIRDLETR 211 A I+ G+SGG L N GELIGI TA++A G + + FA+P+ +++L ++ Sbjct: 229 AAINRGNSGGALVNLNGELIGINTAILAPDGGNI-GIGFAIPSNMVKNLTSQ 279 >ZhtrA [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain EcZ Escherichia coli O157:H7 EDL933 Length = 474 Score = 91.7 bits (226), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 58/172 (33%), Positives = 98/172 (56%), Gaps = 10/172 (5%) Query: 49 QIFSTGSAVVIGPER--LVTNCHVLARASSFKLRRGN-LTLGGKLEFPDPERDLCQVRAE 105 + + GS V+I ++ +VTN HV+ A+ K++ + K+ DP D+ ++ + Sbjct: 109 KFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQ 168 Query: 106 GLKA-PAVTIAPARSLRVGQKVFTLGAPRALEETISDGLLSALR---LDNEGRLRFLQTS 161 K A+ +A + +LRVG +G P L ET++ G++SAL L+ E F+QT Sbjct: 169 NPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTD 228 Query: 162 APISSGSSGGGLFNDKGELIGITTAMIA--GATVQNLSFAVPAEWIRDLETR 211 A I+ G+SGG L N GELIGI TA++A G + + FA+P+ +++L ++ Sbjct: 229 AAINRGNSGGALVNLNGELIGINTAILAPDGGNI-GIGFAIPSNMVKNLTSQ 279 >ECs0165 [O] COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Ecs Escherichia coli O157:H7 Length = 474 Score = 91.7 bits (226), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 58/172 (33%), Positives = 98/172 (56%), Gaps = 10/172 (5%) Query: 49 QIFSTGSAVVIGPER--LVTNCHVLARASSFKLRRGN-LTLGGKLEFPDPERDLCQVRAE 105 + + GS V+I ++ +VTN HV+ A+ K++ + K+ DP D+ ++ + Sbjct: 109 KFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRSDIALIQIQ 168 Query: 106 GLKA-PAVTIAPARSLRVGQKVFTLGAPRALEETISDGLLSALR---LDNEGRLRFLQTS 161 K A+ +A + +LRVG +G P L ET++ G++SAL L+ E F+QT Sbjct: 169 NPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTD 228 Query: 162 APISSGSSGGGLFNDKGELIGITTAMIA--GATVQNLSFAVPAEWIRDLETR 211 A I+ G+SGG L N GELIGI TA++A G + + FA+P+ +++L ++ Sbjct: 229 AAINRGNSGGALVNLNGELIGINTAILAPDGGNI-GIGFAIPSNMVKNLTSQ 279