BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0108.p (408 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2711 [LK] COG1200 RecG-like helicase Rso Ralstonia solanacearum 409 e-114 NMA0675 [LK] COG1200 RecG-like helicase NmA Neisseria meningitid... 326 6e-89 NMB1788 [LK] COG1200 RecG-like helicase Nme Neisseria meningitid... 326 6e-89 PA5345 [LK] COG1200 RecG-like helicase Pae Pseudomonas aeruginosa 257 3e-68 YPO0036 [LK] COG1200 RecG-like helicase Ype Yersinia pestis 249 6e-66 >RSc2711 [LK] COG1200 RecG-like helicase Rso Ralstonia solanacearum Length = 671 Score = 409 bits (1051), Expect = e-114, Method: Compositional matrix adjust. Identities = 206/328 (62%), Positives = 250/328 (76%), Gaps = 8/328 (2%) Query: 47 VLHLPLRYEDETTLMSIAEASMRGLQ--TVQVEGVVTACDVQFHPRRQLIVTVGDDSGQL 104 +LHLP+RYEDET L++IAEA R QV+GVVT +V F PRRQL+V + DDSG+L Sbjct: 1 MLHLPMRYEDETALLTIAEAVARANTGWAAQVDGVVTRNEVAFRPRRQLVVHIADDSGEL 60 Query: 105 TLRFINFYGSQTKQLAEGTRVRVRGELRHGFFGAEMVHPSYKVVNEGAPLPDVLTPVYPA 164 LRF+NFYGSQ KQ+AEG R+RVRGE+R GFFGAEMVHP+ + V PLPD LTPVYP+ Sbjct: 61 VLRFLNFYGSQVKQMAEGARLRVRGEVRGGFFGAEMVHPAVRAVTPDEPLPDRLTPVYPS 120 Query: 165 GEGLSQAYLRKAIANAMSRLDWSDTLPPSMLET----LNLAGFEPSVRLLHNPPPDVDEH 220 G++QAYLRKAI NA+ R +TLP S+L L L +VRLLH P PDVDEH Sbjct: 121 TAGVAQAYLRKAILNALGRTPLPETLPDSLLRGPLAPLKLMAPAEAVRLLHQPTPDVDEH 180 Query: 221 ALIERSHPAWIRMKFDELLAQQLSLKRAQAARRAKTSRALPVTGR--ITEELTKVLPFQL 278 +L+ER+HPAW+R+KFDELLAQQLSLKRAQAARR +++ L G + LPF+L Sbjct: 181 SLVERTHPAWLRIKFDELLAQQLSLKRAQAARRTRSAPVLRAGGADGLLARFLAALPFKL 240 Query: 279 TGAQQRVLEEIRADLRQSFPMQRLLQGDVGSGKTVVAALAAAQAIDSGCQAVLMAPTEIL 338 TGAQ RV EEIRADL + +PMQRLLQGDVGSGKTV+AALAA QAID+G QA LMAPTE+L Sbjct: 241 TGAQARVWEEIRADLARPYPMQRLLQGDVGSGKTVIAALAACQAIDAGRQAALMAPTELL 300 Query: 339 AEQHFRKIAAWMEPLNVGVAWLSGSQKK 366 AEQH+RK++AW+ PL V + WL+GS K+ Sbjct: 301 AEQHYRKLSAWLAPLGVDIVWLAGSLKR 328 >NMA0675 [LK] COG1200 RecG-like helicase NmA Neisseria meningitidis Z2491 Length = 680 Score = 326 bits (835), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 179/347 (51%), Positives = 225/347 (64%), Gaps = 4/347 (1%) Query: 18 APAAKAAAKPAAKPENKLAKLGLHNDMDLVLHLPLRYEDETTLMSIAEASMRGLQTVQVE 77 +P + K KL KL LH DLVLHLPLRYEDET +M I +A + G+ QVE Sbjct: 3 SPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPI-GV-PCQVE 60 Query: 78 GVVTACDVQFHPRRQLIVTVGDDSGQ-LTLRFINFYGSQTKQLAEGTRVRVRGELRHGFF 136 G V +V F PR+QLIV + D SG L LRFI+FY S KQ A G R+R GE++HGF+ Sbjct: 61 GEVIHQEVTFKPRKQLIVQIADGSGSVLFLRFIHFYASHQKQTAIGKRIRAVGEIKHGFY 120 Query: 137 GAEMVHPSYKVVNEGAPLPDVLTPVYPAGEGLSQAYLRKAIANAMSRLDWSDTLPPSMLE 196 G EM+HP + EG L + LTPVYP GL+Q LR+ I A+ DTLP ++L Sbjct: 121 GDEMIHPKIRDA-EGGGLAESLTPVYPTVNGLNQPTLRRIIQTALDVTPLHDTLPDALLC 179 Query: 197 TLNLAGFEPSVRLLHNPPPDVDEHALIERSHPAWIRMKFDELLAQQLSLKRAQAARRAKT 256 L L S+RLLH+PPP H L + + PAW R+KFDELLAQQLS++ A+ R T Sbjct: 180 RLKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGT 239 Query: 257 SRALPVTGRITEELTKVLPFQLTGAQQRVLEEIRADLRQSFPMQRLLQGDVGSGKTVVAA 316 + AL G +T+ L + LPF LT AQ++V+ EI D+ Q++PM RLLQGDVGSGKT+VAA Sbjct: 240 AAALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAA 299 Query: 317 LAAAQAIDSGCQAVLMAPTEILAEQHFRKIAAWMEPLNVGVAWLSGS 363 L+A AI+SG Q +MAPTEILAEQHF K W+EPL + V L GS Sbjct: 300 LSALTAIESGAQVAVMAPTEILAEQHFIKFKQWLEPLGIEVVRLFGS 346 >NMB1788 [LK] COG1200 RecG-like helicase Nme Neisseria meningitidis MC58 Length = 680 Score = 326 bits (835), Expect = 6e-89, Method: Compositional matrix adjust. Identities = 179/347 (51%), Positives = 225/347 (64%), Gaps = 4/347 (1%) Query: 18 APAAKAAAKPAAKPENKLAKLGLHNDMDLVLHLPLRYEDETTLMSIAEASMRGLQTVQVE 77 +P + K KL KL LH DLVLHLPLRYEDET +M I +A + G+ QVE Sbjct: 3 SPETRKQLKITDVSAKKLDKLNLHTAWDLVLHLPLRYEDETHIMPIKDAPI-GV-PCQVE 60 Query: 78 GVVTACDVQFHPRRQLIVTVGDDSGQ-LTLRFINFYGSQTKQLAEGTRVRVRGELRHGFF 136 G V +V F PR+QLIV + D SG L LRFI+FY S KQ A G R+R GE++HGF+ Sbjct: 61 GEVIHQEVTFKPRKQLIVQIADGSGSVLFLRFIHFYASHQKQTAVGKRIRAVGEIKHGFY 120 Query: 137 GAEMVHPSYKVVNEGAPLPDVLTPVYPAGEGLSQAYLRKAIANAMSRLDWSDTLPPSMLE 196 G EM+HP + EG L + LTPVYP GL+Q LR+ I A+ DTLP ++L Sbjct: 121 GDEMIHPKIRDA-EGGGLAESLTPVYPTVNGLNQPTLRRIIQTALDVTPLHDTLPDALLC 179 Query: 197 TLNLAGFEPSVRLLHNPPPDVDEHALIERSHPAWIRMKFDELLAQQLSLKRAQAARRAKT 256 L L S+RLLH+PPP H L + + PAW R+KFDELLAQQLS++ A+ R T Sbjct: 180 RLKLPHLAESLRLLHSPPPSFTIHQLSDGTLPAWQRLKFDELLAQQLSMRLARQKRIGGT 239 Query: 257 SRALPVTGRITEELTKVLPFQLTGAQQRVLEEIRADLRQSFPMQRLLQGDVGSGKTVVAA 316 + AL G +T+ L + LPF LT AQ++V+ EI D+ Q++PM RLLQGDVGSGKT+VAA Sbjct: 240 AAALGGDGTLTQALRQALPFALTDAQEKVVSEICRDMAQTYPMHRLLQGDVGSGKTIVAA 299 Query: 317 LAAAQAIDSGCQAVLMAPTEILAEQHFRKIAAWMEPLNVGVAWLSGS 363 L+A AI+SG Q +MAPTEILAEQHF K W+EPL + V L GS Sbjct: 300 LSALTAIESGAQVAVMAPTEILAEQHFIKFKQWLEPLGIEVVRLFGS 346 >PA5345 [LK] COG1200 RecG-like helicase Pae Pseudomonas aeruginosa Length = 691 Score = 257 bits (657), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 157/338 (46%), Positives = 207/338 (61%), Gaps = 7/338 (2%) Query: 33 NKLAKLGLHNDMDLVLHLPLRYEDETTLMSIAEASMRGLQTVQVEGVVTACDVQFHPRRQ 92 KLA++GL D++ HLPLRY+D T + +I ++R VEGVV DV RR Sbjct: 21 EKLARVGLETLQDILFHLPLRYQDRTRVTAIG--ALRPGADAVVEGVVAGADVVMGRRRS 78 Query: 93 LIVTVGDDSGQLTLRFINFYGSQTKQLAEGTRVRVRGELRHGFFGAEMVHPSYKVVNEGA 152 L+V + D SG L+LRF +F +Q L GT +R GE+R G G E+ HP Y+ +N Sbjct: 79 LLVRLQDGSGTLSLRFYHFSQAQKDGLKRGTHLRCYGEVRPGASGLEIYHPEYRALNGDE 138 Query: 153 PLP--DVLTPVYPAGEGLSQAYLRKAIANAMSRLDWS---DTLPPSMLETLNLAGFEPSV 207 P+P LTP+YP EGL+Q LR+ A++ L S D LP + L + ++ Sbjct: 139 PIPVEQTLTPIYPTTEGLTQQRLRQLSQQALAMLGPSSLPDWLPAELARDYQLGPLDQAI 198 Query: 208 RLLHNPPPDVDEHALIERSHPAWIRMKFDELLAQQLSLKRAQAARRAKTSRALPVTGRIT 267 R LH PPPD D L E H A +R+ F+ELL QLSL+R + A R++ + LP R+ Sbjct: 199 RYLHRPPPDADIEELAEGRHWAQLRLAFEELLTHQLSLQRLREAVRSQAAPRLPAASRLP 258 Query: 268 EELTKVLPFQLTGAQQRVLEEIRADLRQSFPMQRLLQGDVGSGKTVVAALAAAQAIDSGC 327 + L FQ TGAQ+RV EI DL Q PM RL+QGDVG+GKTVVAALAA QAI++G Sbjct: 259 KRFLANLGFQPTGAQRRVGAEIAYDLAQDEPMLRLVQGDVGAGKTVVAALAALQAIEAGY 318 Query: 328 QAVLMAPTEILAEQHFRKIAAWMEPLNVGVAWLSGSQK 365 Q LMAPTEILAEQHF + W++PL++ VAWL+G K Sbjct: 319 QVALMAPTEILAEQHFLNFSKWLQPLDIEVAWLAGKLK 356 >YPO0036 [LK] COG1200 RecG-like helicase Ype Yersinia pestis Length = 693 Score = 249 bits (637), Expect = 6e-66, Method: Compositional matrix adjust. Identities = 158/345 (45%), Positives = 203/345 (58%), Gaps = 13/345 (3%) Query: 28 AAKPENKLAKLGLHNDMDLVLHLPLRYEDETTLMSIAEASMRGLQTVQVEGVVTACDVQF 87 A KLAK+GL DL+LHLPLRYED T L I + + GL +V VEG V D+ F Sbjct: 18 GASQAGKLAKIGLETIQDLLLHLPLRYEDRTRLYRIGDL-LPGL-SVTVEGEVLRSDISF 75 Query: 88 HPRRQLIVTVGDDSGQLTLRFINFYGSQTKQLAEGTRVRVRGELRHGFFGAEMVHPSYKV 147 RR + + D SG LTLRF NF + L+ G V GE + G G E++HP Y+V Sbjct: 76 GRRRMMTCQISDGSGVLTLRFFNFNAAMKNSLSVGKHVIAYGEAKRGNNGPEIIHPEYRV 135 Query: 148 VNE--GAPLPDVLTPVYPAGEGLSQAYLRKAIANAMSRLD---WSDTLPPSMLETLNLAG 202 E G L + LTPVYP EG+ QA LRK I A++ LD ++ LP + + +L Sbjct: 136 HGENIGVELQESLTPVYPTTEGIRQATLRKLIDQALAMLDTCVIAELLPIEL--SRSLIS 193 Query: 203 FEPSVRLLHNPPPDVDEHALIERSHPAWIRMKFDELLAQQLSLKRAQAARRAKTSRALPV 262 ++ LH PP D+ L + HPA R+ +ELLA LS+ +A A++ RALP+ Sbjct: 194 LPEAIHTLHRPPADIQLADLEQGKHPAQRRLIMEELLAHNLSMLAVRAG--AQSYRALPL 251 Query: 263 TG--RITEELTKVLPFQLTGAQQRVLEEIRADLRQSFPMQRLLQGDVGSGKTVVAALAAA 320 ++ + LPF T AQQRV+ EI D+ QSFPM RL+QGDVGSGKT+VAALAA Sbjct: 252 MAEEQLKQRFLAALPFTPTQAQQRVVAEIERDMTQSFPMMRLIQGDVGSGKTLVAALAAL 311 Query: 321 QAIDSGCQAVLMAPTEILAEQHFRKIAAWMEPLNVGVAWLSGSQK 365 +AI G Q LMAPTE+LAEQH W+EPL V WL+G QK Sbjct: 312 RAIAHGKQVALMAPTELLAEQHATTFRQWLEPLGFSVGWLAGKQK 356