BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0090.p (239 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc2648 [GER] COG0697 Permeases of the drug/metabolite transport... 283 2e-76 RSc0233 [GER] COG0697 Permeases of the drug/metabolite transport... 182 4e-46 CC0848 [GER] COG0697 Permeases of the drug/metabolite transporte... 179 3e-45 RSc1428 [GER] COG0697 Permeases of the drug/metabolite transport... 159 4e-39 ytfF [GER] COG0697 Permeases of the drug/metabolite transporter ... 122 8e-28 >AGc2648 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 310 Score = 283 bits (724), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 137/234 (58%), Positives = 181/234 (77%) Query: 2 WLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVSLRKLAPSLALG 61 WLS++GN+ YYVF+++AV+L G+A TS++IGFLPVAV+IIGSR HGAVSL++L PSLA G Sbjct: 74 WLSMIGNIAYYVFISTAVKLSGVAFTSIIIGFLPVAVTIIGSRDHGAVSLKRLWPSLAFG 133 Query: 62 LAGIACVAWQSLSGSAGGDMKQSVIGFFCALAALVSWTTYAVGNSRWLARLHEVSAHDWN 121 GI ++WQSL+ + G +IG AL AL SWT +AVGN+RWL+RLH+VSA DWN Sbjct: 134 AIGIVGISWQSLTENDAGLDVSRLIGLASALGALASWTAFAVGNARWLSRLHDVSADDWN 193 Query: 122 LLIGVVTGLLSLFIAVPAFTVMLQPHPGSEWMHFVAVSAGVAIFASLFGNACWNKASRLL 181 ++ GVVTG L+L +A+PAF + H +W+HF A++AG+ AS+ GNA WN+ SR+L Sbjct: 194 MMTGVVTGGLALLLAIPAFGFGGESHSSGDWLHFAAIAAGLGFTASILGNAFWNRMSRML 253 Query: 182 PLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTVSVLLCVSAHRVDE 235 PLTM+GQMILFETLFALLYGFLWE PT +EI A+ V +SV+LC+ AHR ++ Sbjct: 254 PLTMVGQMILFETLFALLYGFLWEGHGPTFVEIVAICSVVLSVVLCMRAHRPEK 307 >RSc0233 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 326 Score = 182 bits (463), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 110/235 (46%), Positives = 150/235 (63%), Gaps = 4/235 (1%) Query: 1 VWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVSLRKLAPSLAL 60 V LSL GNV+YY+ +A VQ G+A SL++G LPV V++ G+ HG++ LR+LA L + Sbjct: 91 VLLSLPGNVLYYLCVAGGVQRAGVAPVSLIVGLLPVTVTLAGAAEHGSLPLRRLALPLLM 150 Query: 61 GLAGIACVAWQSLSGSAGGDMKQSVIGFFCALAALVSWTTYAVGNSRWLARLHEVSAHDW 120 AG+AC+ + + AG ++G A AL WT YAV N+R+L R + ++ +W Sbjct: 151 AAAGVACIYADAPATQAGAGGATHLLGLLMAAGALACWTVYAVCNARYLRRHPQFTSREW 210 Query: 121 NLLIGVVTGLLSLFIAVPAFTV----MLQPHPGSEWMHFVAVSAGVAIFASLFGNACWNK 176 +LL G+ TG LSL +AVPAF + P P S W F V+ GVA+ AS+ GN+ WN Sbjct: 211 SLLTGIATGALSLVLAVPAFLMPGMATAAPQPASAWGLFWLVNTGVALGASVLGNSLWNT 270 Query: 177 ASRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTVSVLLCVSAH 231 ASR LPLT+ GQMI+FET+FALLYGF+ E RWP LE+AA +L+ V L H Sbjct: 271 ASRKLPLTLSGQMIVFETVFALLYGFIQEGRWPHGLEVAAALLLMSGVGLAARRH 325 >CC0848 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ccr Caulobacter vibrioides Length = 312 Score = 179 bits (455), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 108/223 (48%), Positives = 141/223 (63%) Query: 10 VYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVSLRKLAPSLALGLAGIACVA 69 +YYV LA AVQ G+A+ SLVIG LPV ++++G++ LR+L LAL +AG C+ Sbjct: 84 IYYVGLAIAVQSAGVALASLVIGLLPVTITLVGAKAGEGTPLRRLVWPLALIVAGGVCIN 143 Query: 70 WQSLSGSAGGDMKQSVIGFFCALAALVSWTTYAVGNSRWLARLHEVSAHDWNLLIGVVTG 129 + + + M ++++G AL AL WT YAV N+R LA + ++H+W+LL GV TG Sbjct: 144 LDAFAAAGRAGMSKTLVGLLGALLALAVWTAYAVWNARRLAATPKFNSHEWSLLTGVATG 203 Query: 130 LLSLFIAVPAFTVMLQPHPGSEWMHFVAVSAGVAIFASLFGNACWNKASRLLPLTMIGQM 189 LLSL I VPAF + H W F VS VAI AS+ GN WN ASRLLPL++ GQ+ Sbjct: 204 LLSLVIVVPAFAFDGKTHAAGAWGLFWGVSFAVAIGASVIGNGLWNAASRLLPLSLSGQL 263 Query: 190 ILFETLFALLYGFLWEQRWPTLLEIAAMVLVTVSVLLCVSAHR 232 I+FET+FALLYGFL E RWP LE AM L+ VL HR Sbjct: 264 IVFETVFALLYGFLHEGRWPRSLESVAMALMLAGVLWSARLHR 306 >RSc1428 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 159 bits (403), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 110/237 (46%), Positives = 140/237 (59%), Gaps = 8/237 (3%) Query: 7 GNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVSLRKLAPSLALGLAGIA 66 GN+VYYV LA VQL G+A SL+IG LP+ V+++G R HGAV L +LA L + AGIA Sbjct: 75 GNLVYYVLLAFGVQLAGVAPVSLIIGVLPITVTVLGRRDHGAVPLSRLAWPLLVVAAGIA 134 Query: 67 CVAWQSLSGSA--GGDMK---QSVIGFFCALAALVSWTTYAVGNSRWLARLHEVSAHDWN 121 C+ S A GD + G CA AL SWT YA+ N+R L R S+++W+ Sbjct: 135 CINIDLFSHDAVAAGDAHPIWSRIAGIACAAGALCSWTWYAIDNARHLQRNPHFSSNEWS 194 Query: 122 LLIGVVTGLLSLFIAVPAFTVML---QPHPGSEWMHFVAVSAGVAIFASLFGNACWNKAS 178 L G+ TG LS + A G W F AV+A VA+ ASL GN WN A+ Sbjct: 195 ALYGISTGALSAALTAAAVLAAGTGWAEGGGRVWTTFWAVNAAVALGASLIGNNLWNIAA 254 Query: 179 RLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTVSVLLCVSAHRVDE 235 R LPLT+ GQMI+FETLFAL YGF+++ RWP LE+AA+ L+ V V V H D Sbjct: 255 RRLPLTLSGQMIVFETLFALAYGFVYDHRWPRPLEMAAIALLIVGVGWSVRLHADDN 311 >ytfF [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Eco Escherichia coli K12 Length = 324 Score = 122 bits (306), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 80/244 (32%), Positives = 128/244 (52%), Gaps = 19/244 (7%) Query: 3 LSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIG----SRGHGAVSLRKLAPSL 58 L+++GN++YY LASA+Q G +++++IG LPV + + S+ G ++ KLAP+L Sbjct: 73 LTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLPVVIPVFANLLYSQRDGKLAWGKLAPAL 132 Query: 59 ALGLAGIACVAWQSLS-GSAGGDMKQSVIGFFCALAALVSWTTYAVGNSRWLARLHEVSA 117 G+ACV L+ G D + G AL ++V W YA+ N+RWL + Sbjct: 133 ICIGIGLACVNIAELNHGLPDFDWARYTSGIVLALVSVVCWAWYALRNARWLRENPDKHP 192 Query: 118 HDWNL----------LIGVVTGLLSLFIAVPAFTVMLQPHPGSEWMHFVAVSAGVAIFAS 167 W LIG + L P F++ P P + F+++ +A+ S Sbjct: 193 MMWATAQALVTLPVSLIGYLVACYWLNTQTPDFSLPFGPRP----LVFISLMVAIAVLCS 248 Query: 168 LFGNACWNKASRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTVSVLLC 227 G CWN AS+LLP ++G +I+FETL LLY FL Q+ P L+ ++ + L+ + V++ Sbjct: 249 WVGALCWNVASQLLPTVILGPLIVFETLAGLLYTFLLRQQMPPLMTLSGIALLVIGVVIA 308 Query: 228 VSAH 231 V A Sbjct: 309 VRAK 312