BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0037.0005.p (455 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4900 [GEPR] COG0477 Permeases of the major facilitator superfa... 385 e-107 RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 276 6e-74 Cgl2967 [GEPR] COG0477 Permeases of the major facilitator superf... 246 7e-65 Cgl2357 [GEPR] COG0477 Permeases of the major facilitator superf... 235 1e-61 AGc4589 [GEPR] COG0477 Permeases of the major facilitator superf... 232 1e-60 >PA4900 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 446 Score = 385 bits (990), Expect = e-107, Method: Compositional matrix adjust. Identities = 217/452 (48%), Positives = 302/452 (66%), Gaps = 12/452 (2%) Query: 1 MKTQEVSQIIDGARFTQFHWMVMCLCALLLVFDGYDLFIYGAVLPVLMKEWSLSPVQAGA 60 M Q + +ID ARF + HW+++ +++FDGYD+ IYG+V+P LM+EW LSPVQAG Sbjct: 1 MNRQSAAAVIDAARFNRTHWLILGWGCFIMLFDGYDMVIYGSVVPRLMQEWQLSPVQAGT 60 Query: 61 LGSYALFGMMFGAFVFGPLADRIGRKKGVAISFVLFSVSTFLSGFATSPGEFGIFRFLAG 120 LGS ALFGM+FG + PLADR GR++ V + +L S++ FL+G A P E G RF G Sbjct: 61 LGSCALFGMLFGGTLLAPLADRFGRRRLVIATTLLASLAAFLTGHARDPLELGAGRFFTG 120 Query: 121 LGCGGLMPNAVALMNEYAPKRLRSTLVAIMFSGYSLGGVLCAGLGIWMLPNFGWQSMFFA 180 L G L+P+A+ L++E+AP RSTLV +M + YS+G VL A L I M+P +GWQS+F+ Sbjct: 121 LALGALVPSAINLISEFAPAGRRSTLVTVMSAFYSVGAVLSALLAIAMIPAWGWQSVFYV 180 Query: 181 AAVPLVLLPVILWKLPESVGFLLRAGKQEQARAMLAQVAPQAALGADVQLVQSDAKGSGA 240 A +P++ +P++L LPES FL G++ + A+L +V P GA+ +++A + A Sbjct: 181 AVLPVLAVPLMLRWLPESAAFLELKGRRAELDALLRKVDPDYRPGAE----RANAVAAEA 236 Query: 241 P---MLDLFKQERTLGTLMIWVAFFCCLLMVYALGSWLPKLMASAGYSLGSSLSFLLALN 297 P + LF+ + +GTL++WVAF C+LM Y L +WLPKLMA GY+LGSSL+FL+ LN Sbjct: 237 PSGRVAQLFEGRQAVGTLLLWVAFAMCMLMSYGLNTWLPKLMAGGGYALGSSLAFLVTLN 296 Query: 298 FGGVVGAIGGGWLGDRFTLPKVVVSFFAVGTVAIALLGFNSPTPVLYLLIIVAGATTIGT 357 G +GA+ GGWL DR + +V FFA+ ++A LG +L L++VAGATTIGT Sbjct: 297 VGATLGALFGGWLADRLGAGRTLVLFFALAAASLAALGLGPGPWLLNGLLVVAGATTIGT 356 Query: 358 QILLYANTAQFYPLAIRSTGLGWASGVGRSGAIVGPLLGGALMAAALPLKMNFLVFAVPG 417 +++A AQFYP +RSTG+GWA+GVGR GAI GP+LGG+L+A LP + NFL FA PG Sbjct: 357 LAVIHAYAAQFYPAWVRSTGVGWAAGVGRLGAIAGPMLGGSLLALELPFQQNFLAFAAPG 416 Query: 418 LVAALAIGIFLLRYRHGQRAVAAETAPTVTAT 449 ++ ALAI LR R V AE + TA Sbjct: 417 VIGALAIACIHLRPR-----VPAEASVDATAK 443 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 276 bits (707), Expect = 6e-74, Method: Compositional matrix adjust. Identities = 169/433 (39%), Positives = 251/433 (57%), Gaps = 5/433 (1%) Query: 5 EVSQIIDGARFTQFHWMVMCLCALLLVFDGYDLFIYGAVLPVLMKEWSLSPVQAGALGSY 64 +V +D RF+ F W V+ LC ++ DG+D G + P L ++W + P G + S Sbjct: 9 DVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTVFSA 68 Query: 65 ALFGMMFGAFVFGPLADRIGRKKGVAISFVLFSVSTFLSGFATSPGEFGIFRFLAGLGCG 124 L G+M GA +FGPLADRIGRK+ + + F +++ LS FA S G RFL GLG G Sbjct: 69 GLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGLGLG 128 Query: 125 GLMPNAVALMNEYAPKRLRSTLVAIMFSGYSLGGVLCAGLGIWMLPNFGWQS-MFFAAAV 183 G MPNA+AL +EY P+R R+ L +MF G++LG + ++P FGW+S + F + Sbjct: 129 GAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFGGVI 188 Query: 184 PLVLLPVILWKLPESVGFLLRAGKQEQARA-MLAQVAP-QAALGADVQLVQSDAKGS-GA 240 PL+LLPV+++ LPESV +L+ G Q A +L ++AP Q L ++ AKG+ G+ Sbjct: 189 PLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKGAPGS 248 Query: 241 PMLDLFKQERTLGTLMIWVAFFCCLLMVYALGSWLPKLMASAGYSLGSSLSFLLALNFGG 300 P+ LF GTL++W FF LL+VY + +WLP L+ S G +L + + GG Sbjct: 249 PVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMYQLGG 308 Query: 301 VVGAIGGGWLGDRFTLPKVVVSFFAVGTVAIALLGFNSPTPVLYLLIIVAGATTIGTQIL 360 VGA+ G + DR+ V+ + +G + L G + T +L + + G G+QI Sbjct: 309 TVGALVIGRMMDRYPATVVLCCTYGLGAGFLVLTGVSQGT-MLAIAVTGVGFCISGSQIG 367 Query: 361 LYANTAQFYPLAIRSTGLGWASGVGRSGAIVGPLLGGALMAAALPLKMNFLVFAVPGLVA 420 A AQFYP A R TG+ WA G+GR G++ G L+GG L+AA + ++ FL+ AVP +A Sbjct: 368 ANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAVPAAIA 427 Query: 421 ALAIGIFLLRYRH 433 +LAI + + RH Sbjct: 428 SLAIFLCGAQARH 440 >Cgl2967 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 444 Score = 246 bits (629), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 154/390 (39%), Positives = 219/390 (56%), Gaps = 33/390 (8%) Query: 30 LVFDGYDLFIYGAVLPVLMKEWSLSPVQAGALGSYALFGMMFGAFVFGPLADRIGRKKGV 89 ++FDGYDL +YG V L KEW+LS G +GS A FGM GA G L+DR+GRK V Sbjct: 51 VIFDGYDLIVYGTVQSALAKEWNLSSATLGTIGSTAFFGMAIGAVFIGRLSDRVGRKAAV 110 Query: 90 AISFVLFSVSTFLSGFATSPGEFGIFRFLAGLGCGGLMPNAVALMNEYAPKRLRSTLVAI 149 S ++ SV T L FA +P FG FRF+AGLG GGL+P+ A+ ++ P++ S + Sbjct: 111 IGSVLILSVFTMLCAFAPNPWVFGAFRFIAGLGLGGLVPSVNAMTSDLVPRKTMSAWATV 170 Query: 150 MFSGYSLGGVLCAGLGIWMLPN---FGWQSMFFAAAVPLVL-LPVILWKLPESVGFLLRA 205 M SG +GG + A L + ++P+ +GW+ MF A +PLV+ LP+ + +P +A Sbjct: 171 MMSGVPIGGSIAAVLALVVVPSSEEWGWRFMFLIALIPLVVGLPIAMKVIPSD-----KA 225 Query: 206 GKQEQARAMLAQVAPQAALGADVQLVQSDAKGSGAPMLDLFKQERTLGTLMIWVAF--FC 263 K + D++ + G ++D ++ + IW A F Sbjct: 226 IKADH----------------DIREGHDEPAGFKDLLVDRYRW------ISIWFALATFV 263 Query: 264 CLLMVYALGSWLPKLMASAGYSLGSSLSFLLALNFGGVVGAIGGGWLGDRFTLPKVVVSF 323 LL Y LG+WLP+LM +AGY G +L F LALN G V+G++ W GDRF + V Sbjct: 264 TLLAWYGLGTWLPRLMETAGYEFGHALMFTLALNLGAVIGSVVTAWAGDRFGPIRSGVIA 323 Query: 324 FAVGTVAIALLGFNSPTPVLYLLIIVAGATTIGTQILLYANTAQFYPLAIRSTGLGWASG 383 + +A+ LL P +Y+++I+AG T GTQIL+ A A FYP +R T LGWA G Sbjct: 324 AGIAGIALLLLLTYPPVTAVYVILILAGVGTHGTQILIIAAVANFYPSNLRGTALGWALG 383 Query: 384 VGRSGAIVGPLLGGALMAAALPLKMNFLVF 413 VGR GA+V P L G L+A L + NF++F Sbjct: 384 VGRIGAVVAPQLAGLLLAWNLGVNSNFIMF 413 >Cgl2357 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 446 Score = 235 bits (600), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 151/404 (37%), Positives = 221/404 (54%), Gaps = 12/404 (2%) Query: 7 SQIIDG---ARFTQFHWMVMCLCALLLVFDGYDLFIYGAVLPVLMKE----WSLSPVQAG 59 SQI G A+ +MV+ + + ++FDGYDL IYGAVL L+++ +LSP AG Sbjct: 3 SQISGGWQSAKHRTTVYMVLVVVGISILFDGYDLVIYGAVLSTLLEDPTQIGALSPAVAG 62 Query: 60 ALGSYALFGMMFGAFVFGPLADRIGRKKGVAISFVLFSVSTFLSGFATSPGEFGIFRFLA 119 LGSYA+ G+M GA G + DR+GR+K + + V FSV L+ FA+S FG RFL Sbjct: 63 TLGSYAMIGVMIGALSAGAVGDRLGRRKVMLTAIVWFSVGMALTAFASSIALFGFLRFLT 122 Query: 120 GLGCGGLMPNAVALMNEYAPKRLRSTLVAIMFSGYSLGGVLCAGLGIWMLPNFGWQSMFF 179 GLG G ++ A++ E+AP R+ AI++SG GGVL + L + GW+ +F Sbjct: 123 GLGVGMIVATGGAIIAEFAPANRRNLFNAIVYSGVPAGGVLASILALLFEDVIGWRGLFL 182 Query: 180 AAAVPLV-LLPVILWKLPESVGFLLRAGKQEQARAMLAQVAPQAALGADVQLVQSDAKGS 238 PL+ LLP+ + LPES +L G+ A+A+ A+ L + +V+ + Sbjct: 183 IGGSPLLFLLPLAYFFLPESPRWLTSRGRAADAKALCARYG----LPTEEFVVEKQQETK 238 Query: 239 GAPMLDLFKQERTLGTLMIWVAFFCCLLMVYALGSWLPKLMASAGYSLGSSLSFLLALNF 298 G +F + +GT++I F LL Y L +WLPK+M S G + SL LL LN Sbjct: 239 GTGFAGIFSSKYLMGTILIGAMSFIGLLSTYGLNTWLPKIMESNGATSHDSLYSLLFLNG 298 Query: 299 GGVVGAIGGGWLGDRFTLPKVVVSFFAVGTVAIALLGFNSPTPVLYLLIIVAGATTIGTQ 358 G V G + W DR V+ S FA+ + + +L S P++Y I AG +GTQ Sbjct: 299 GAVFGGLIASWFADRIGAKTVITSTFALAAICLGVLPNISSWPMMYTAIAFAGVGVLGTQ 358 Query: 359 ILLYANTAQFYPLAIRSTGLGWASGVGRSGAIVGPLLGGALMAA 402 +L Y T+ F+ R+ G+ W +G GR G IVGP +GG ++ A Sbjct: 359 VLTYGLTSNFFGTECRAAGVAWCAGFGRLGGIVGPAIGGLIIGA 402 >AGc4589 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 477 Score = 232 bits (592), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 159/418 (38%), Positives = 232/418 (55%), Gaps = 22/418 (5%) Query: 22 VMCLCALLLVFDGYDLFIYGAVLPVLMKE--WSLSPVQAGALGSYALFGMMFGAFVFGPL 79 V+ C L+++FDGYDL +YGAV P L+KE W+L+P G + L GM+ GA G + Sbjct: 68 VIATCGLMIMFDGYDLVVYGAVAPALLKESTWALNPAMVGRAAALTLVGMLLGALFAGTM 127 Query: 80 ADRIGRKKGVAISFVLFSVSTFLSGFATSPGEFGIFRFLAGLGCGGLMPNAVALMNEYAP 139 ADRIGR+K V +S FS S + F I RF AGLG G L+P AL+ E++P Sbjct: 128 ADRIGRRKVVLLSLAGFSAMMIASAMTPNFLAFEITRFFAGLGLGALLPTVTALVLEFSP 187 Query: 140 KRLRSTLVAIMFSGYSLGGVLCAGLGIWMLPNFGWQSMFFAAAVPLVLLPVILWKLPESV 199 + R+ ++ F GY +GG++ LG+ +L ++GW+ + +PL+LLP+ + LPES Sbjct: 188 PQRRAQANSLSFLGYLIGGIISGILGMLLLESYGWRPLMLIGGLPLILLPIFMRFLPESP 247 Query: 200 GFLLRAGKQEQARAM-----LAQVAPQAALGADVQLVQSDAKGSGAPMLDLFKQERTLGT 254 +L G+Q +A + L ++ P A + G GA LF + R T Sbjct: 248 EWLASKGRQAEADGICDSYGLQRIVPHAKM---------QKGGVGA----LFSEGRLAST 294 Query: 255 LMIWVAFFCCLLMVYALGSWLPKLMASAGYSLGSSLSFLLALNFGGVVGAIGGGWLGDRF 314 L W FC LL+ + + +WLP +M GY + S+LSF + LN G +G + GG D+ Sbjct: 295 LNAWGIHFCSLLLTFGMVNWLPTIMNKMGYDISSALSFSVMLNVGAAIGILIGGRFADKG 354 Query: 315 TLPKVVVSFFAVGTVAIALLGFNSPTPVLYLLIIVAGATTIGTQILLYANTAQFYPLAIR 374 + VV FAVG +I L N P+LY+ + +AGA TIGTQIL + YP+ IR Sbjct: 355 NVKVVVAILFAVGAASIFALTANK-GPLLYVFVALAGAGTIGTQILANVLVGRLYPVHIR 413 Query: 375 STGLGWASGVGRSGAIVGPLLGGALMAAALPLKMNFLVFAVPGLVAALAIGIFLLRYR 432 TGLG++ VGR G I GP++GG ++ L + NF +F +V L + + L YR Sbjct: 414 GTGLGFSLAVGRLGGIAGPMIGGLVLQRGLAPEWNFYIFGSVAVV-GLMLTVLTLLYR 470