BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0406.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM4270 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 240 3e-63 VC2103 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae 217 3e-56 BS_ywbI [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis 202 9e-52 PA3433 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 157 3e-38 SA2330 [K] COG0583 Transcriptional regulator Sau Staphylococcus ... 154 3e-37 >STM4270 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 295 Score = 240 bits (612), Expect = 3e-63, Method: Compositional matrix adjust. Identities = 127/290 (43%), Positives = 186/290 (64%), Gaps = 3/290 (1%) Query: 1 MDIRALRYFTETVRLASFSRAADALHVTQSTVSKMVRQLEDEVDAPLLVRDGRRLQLTDT 60 MDIR LRYF E VR SF+RAA+ L VTQ T+SKM++ LEDE++ LL+RDGR+L LTDT Sbjct: 1 MDIRTLRYFVEVVRQQSFTRAAEKLFVTQPTISKMLKNLEDELNCTLLIRDGRKLLLTDT 60 Query: 61 GRVVYEQGQQILASMQRLDAEVRDTKALRCGRLEIGIPPMINILCTPVLKAFRERHPEIA 120 GRVV+E+G ILA ++L+AE+ D L G L +GIPPM+ +L + FR+R+P + Sbjct: 61 GRVVFERGLAILAEFRQLEAELSDINHLNKGVLRLGIPPMVGMLMAGPISLFRQRYPGVE 120 Query: 121 IVLKEDTGPQIEERVANGELEIGMTVLPADPELELQTLPVARYPMWA-VAQAGRFQKNRA 179 + + E G +++ V NGEL++ MT LP + L TL + +P+ V ++G++ + Sbjct: 121 LKISEFGGLTVQQAVMNGELDVAMTALPVEEASGLTTLSLFSHPLCVLVPRSGQWTTGDS 180 Query: 180 TLRCAQLDGMPLVLLNNEFGLTRSLRGMFGELGIRPEIVAQSAQWDWLVAMALAGMGAAL 239 A L PL++ N +F L+R L +F + ++P I +S QWD+L AM AG+G A+ Sbjct: 181 IAPEA-LAEHPLLIYNEDFALSRQLMTLFSQHDVKPRIAVRSGQWDFLAAMVQAGVGIAI 239 Query: 240 LPEPFIHRLATDQLQAVRLVEPEVQWQVAYVTRGGGYLSHAARAWMALSE 289 LPEP RL L+ + L E +++WQ+ + R G YLSH+ARAW+ E Sbjct: 240 LPEPICQRLDKATLRWLPL-ESDLRWQLGMIWREGVYLSHSARAWLTCCE 288 >VC2103 [K] COG0583 Transcriptional regulator Vch Vibrio cholerae Length = 292 Score = 217 bits (552), Expect = 3e-56, Method: Compositional matrix adjust. Identities = 108/288 (37%), Positives = 173/288 (60%), Gaps = 1/288 (0%) Query: 1 MDIRALRYFTETVRLASFSRAADALHVTQSTVSKMVRQLEDEVDAPLLVRDGRRLQLTDT 60 MDIRALRYF E V SF++A++ L VTQ T+SKM+R LE E++ PLL R+GRR LT+ Sbjct: 1 MDIRALRYFVELVNQQSFTKASERLFVTQPTISKMIRNLEQELEQPLLHREGRRFWLTEA 60 Query: 61 GRVVYEQGQQILASMQRLDAEVRDTKALRCGRLEIGIPPMINILCTPVLKAFRERHPEIA 120 G +VY++ QQIL MQ+LDAE+ D L G L +GIPPM+ + + + +R+ +P + Sbjct: 61 GEIVYQRAQQILTQMQQLDAELTDLNQLHRGHLRLGIPPMVGHVYARLFRQYRQTYPNVE 120 Query: 121 IVLKEDTGPQIEERVANGELEIGMTVLPADPELELQTLPVARYPMWAVAQAGRFQKNRAT 180 + + E G +IE+ + +G++++ +T+L + +L T+ + YP++AV ++ T Sbjct: 121 LTVVEYGGRKIEQAILDGDIDVAVTMLSPNQHPDLNTVALDHYPIFAVVPDIPLWRSLTT 180 Query: 181 LRCAQLDGMPLVLLNNEFGLTRSLRGMFGELGIRPEIVAQSAQWDWLVAMALAGMGAALL 240 L AQ+ P L +EF L+ + G P++ A+S+QWD+LVA+ +G+G L Sbjct: 181 LTWAQISQEPFYLFTHEFTLSDHIHTCCQAAGYTPQVAARSSQWDFLVALVKSGVGVCFL 240 Query: 241 PEPFIHRLATDQLQAVRLVEPEVQWQVAYVTRGGGYLSHAARAWMALS 288 P P R+ D + + + P + W++ V Y+S A AW+AL Sbjct: 241 PAPLCQRIQGDGV-LIYPITPAIDWRLGVVWHRERYVSKTAEAWIALC 287 >BS_ywbI [K] COG0583 Transcriptional regulator Bsu Bacillus subtilis Length = 301 Score = 202 bits (513), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 101/286 (35%), Positives = 164/286 (57%), Gaps = 2/286 (0%) Query: 1 MDIRALRYFTETVRLASFSRAADALHVTQSTVSKMVRQLEDEVDAPLLVRDGRRLQLTDT 60 MDIR L YF E RL SF++A+ +L+V+Q T+SKM++ LE+E+ L R+GR+++LTD Sbjct: 1 MDIRHLTYFLEVARLKSFTKASQSLYVSQPTISKMIKNLEEELGIELFYRNGRQVELTDA 60 Query: 61 GRVVYEQGQQILASMQRLDAEVRDTKALRCGRLEIGIPPMINILCTP-VLKAFRERHPEI 119 G +Y Q Q+I+ S Q L +E+ D ++ G + IG+PPMI P VL FRE +P + Sbjct: 61 GHSMYVQAQEIIKSFQNLTSELNDIMEVKKGHVRIGLPPMIGSGFFPRVLGDFRENYPNV 120 Query: 120 AIVLKEDTGPQIEERVANGELEIGMTVLPADPELELQTLPVARYPMWAVAQAGRFQKNRA 179 L ED +++E V +G L+IG+ VLPA+ ++ + + + + V + Sbjct: 121 TFQLVEDGSIKVQEGVGDGSLDIGVVVLPANEDI-FHSFTIVKETLMLVVHPSHRLADEK 179 Query: 180 TLRCAQLDGMPLVLLNNEFGLTRSLRGMFGELGIRPEIVAQSAQWDWLVAMALAGMGAAL 239 + +L P + +F L + + G RP I+ +++QWD++ M A +G L Sbjct: 180 ECQLRELKDEPFIFFREDFVLHNRIMTECIKAGFRPHIIYETSQWDFISEMVSANLGIGL 239 Query: 240 LPEPFIHRLATDQLQAVRLVEPEVQWQVAYVTRGGGYLSHAARAWM 285 LPE L ++++ + LV+P + W +A + R YLS AARAW+ Sbjct: 240 LPERICRGLDPEKVKVIPLVDPVIPWHLAIIWRKDRYLSFAARAWL 285 >PA3433 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 157 bits (397), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 100/291 (34%), Positives = 151/291 (51%), Gaps = 3/291 (1%) Query: 1 MDIRALRYFTETVRLASFSRAADALHVTQSTVSKMVRQLEDEVDAPLLVRDGRRLQLTDT 60 M+ R LR F E VR SF++AA H +QST+SK V QLE + +L R+G ++LTD Sbjct: 1 MEFRQLRSFVEVVRQGSFTQAAQVRHASQSTISKQVAQLEQSLGVQVLERNGPHVRLTDA 60 Query: 61 GRVVYEQGQQILASMQRLDAEVRDTKALRCGRLEIGIPPM-INILCTPVLKAFRERHPEI 119 G VV+ + +++L + L +E+ D L G L +G+P + + L +R R+P I Sbjct: 61 GAVVFRRAEEMLRLRRDLLSELDDLSQLNRGELRLGLPLLGADALFAQRFAEYRRRYPNI 120 Query: 120 AIVLKEDTGPQIEERVANGELEIGMTVLPADPELELQTLPVARYPMWAVAQAGRFQKNRA 179 A+ L E +E+ V GELE+ ++ PAD + Q P P+ + AG + A Sbjct: 121 AVHLVEGGSKTMEQAVLAGELELAGSLTPADDGFDYQ--PFCNEPLDVLLPAGHPKAAAA 178 Query: 180 TLRCAQLDGMPLVLLNNEFGLTRSLRGMFGELGIRPEIVAQSAQWDWLVAMALAGMGAAL 239 ++ +L P +L F L L E G P +S Q D+L A+ A G L Sbjct: 179 SVALGELADSPFLLYQQSFTLNDRLLRACLEAGFSPREGGRSGQADFLGALVAANQGVVL 238 Query: 240 LPEPFIHRLATDQLQAVRLVEPEVQWQVAYVTRGGGYLSHAARAWMALSEE 290 LP + + V L EP+++W +A++ R GGYLS AA+AW+ L E Sbjct: 239 LPRVIAREIERPGVVRVLLREPDLRWDIAFIWRRGGYLSRAAQAWLELLRE 289 >SA2330 [K] COG0583 Transcriptional regulator Sau Staphylococcus aureus N315 Length = 295 Score = 154 bits (388), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 82/288 (28%), Positives = 150/288 (52%), Gaps = 3/288 (1%) Query: 1 MDIRALRYFTETVRLASFSRAADALHVTQSTVSKMVRQLEDEVDAPLLVRDGRRLQLTDT 60 +DI+ ++YF E V+ + A+ +L++ Q T+SK ++ +E+E+ PL R R L LTD Sbjct: 4 VDIKHMKYFIEVVKQGGMTNASKSLYIAQPTISKAIKDIENEMGTPLFDRSKRHLILTDA 63 Query: 61 GRVVYEQGQQILASMQRLDAEVRDTKALRCGRLEIGIPPMINI-LCTPVLKAFRERHPEI 119 G++ YE+ ++I+A L +E+ L G + +G+ ++N+ + +L AF +++P + Sbjct: 64 GQIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMNMKILINILGAFHQQYPNV 123 Query: 120 AIVLKEDTGPQIEERVANGELEIGMTVLPADPELELQTLPVARYPMWAVAQAGRFQKNRA 179 L E+ G IE+++ N E++IG+T LP D + T V++ R K Sbjct: 124 TYNLIENGGKTIEQQIINDEVDIGVTTLPVDHHIFDYTTLDKEDLRLIVSREHRLAK-YE 182 Query: 180 TLRCAQLDGMPLVLLNNEFGLTRSLRGMFGELGIRPEIVAQSAQWDWLVAMALAGMGAAL 239 T++ L G +L N +F L + +G P VAQ +QW + + +G ++ Sbjct: 183 TVKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTVAQISQWHVIEDLVTNELGISI 242 Query: 240 LPEPFIHRLATDQLQAVRLVEPEVQWQVAYVTRGGGYLSHAARAWMAL 287 LP +L D ++ +R+ + V W++ V + LSHA W+ Sbjct: 243 LPTSISEQLNGD-VKLLRIEDAHVHWELGVVWKKDKQLSHATTKWIEF 289