BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0396.p (433 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3069 [GEPR] COG0477 Permeases of the major facilitator superf... 309 7e-84 ZynfM [GEPR] COG0477 Permeases of the major facilitator superfam... 309 1e-83 ECs2302 [GEPR] COG0477 Permeases of the major facilitator superf... 308 1e-83 ynfM [GEPR] COG0477 Permeases of the major facilitator superfami... 308 2e-83 PA5030 [GEPR] COG0477 Permeases of the major facilitator superfa... 294 3e-79 >RSc3069 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 428 Score = 309 bits (792), Expect = 7e-84, Method: Compositional matrix adjust. Identities = 198/388 (51%), Positives = 244/388 (62%), Gaps = 4/388 (1%) Query: 43 VRGSAAYRNIVLALFCSGFATFSLLYCVQPLLPAFAQEFGIGAASASLALSLSTGFLAVS 102 VRGS YR LALF +GF+TFSLLYCVQPL+P +FG+ A SL LS +T LA + Sbjct: 32 VRGSPGYRRANLALFAAGFSTFSLLYCVQPLMPLLGHDFGLSPAQTSLVLSATTMLLAFA 91 Query: 103 ILLAGMVSERYGRKELMFASLATAACCNLLAGVAPNWELILVVRAVEGIALGGVPAVAMA 162 IL AG++SE RK LM SL ++ + A V P W+ +L RAV G+ LGGVPAVAMA Sbjct: 92 ILFAGLLSESIHRKTLMGVSLVLSSALTVAAAVLPGWQGLLATRAVLGVVLGGVPAVAMA 151 Query: 163 YLAEEIDASGLGYAMGLYVGGNAFGGMVGRVAMSTMSEHIGWRHAMLVIGALDLALAVAF 222 YLAEE+ GLG AMGLYVGG AFGGM GRV ++++ GWR AM IGAL L A+AF Sbjct: 152 YLAEEVHPQGLGMAMGLYVGGTAFGGMAGRVLTGMVADYAGWRVAMGFIGALCLLAALAF 211 Query: 223 VLMLPASRNFVRNGTMQLRDHVALWKRHLGHARLPLTFGIAALNMGIFATSYNYAGFRLM 282 +LP SR F + L D HL L F +A L MG F T YNYA +RL+ Sbjct: 212 AWLLPPSRRFAPRRGVALADLFDTLAEHLREPGLRALFAMAFLLMGGFVTIYNYASYRLL 271 Query: 283 SPPFSLSATLTGLIFSAYIFGIVSSSWAGSLADRYGRAPLVAAGIATSCAGLFLTCTSSL 342 S P++LS + G IF Y+ GI +S+W G LADR+GR ++ AG A AG+ +T L Sbjct: 272 SAPYALSHSAVGAIFMVYLLGIGASTWFGRLADRHGRGRVLLAGTAAMSAGVLMTLAMPL 331 Query: 343 ALVITGIVLLTIGFFTTHSAASSWVGRMASSGRGHAASLYLLSYYLGGSVLGSAGGWFWE 402 LVI GI LLT GFF H+ AS WVGR A +G AA+LYLL+YYLG S+ G+AGG + Sbjct: 332 GLVIGGIALLTFGFFGAHAVASGWVGRRARRAKGQAAALYLLAYYLGSSIAGTAGGKLYA 391 Query: 403 HSGWNAVAAF----MLLQVLTAAWLARR 426 GW V A + +LTAAWL RR Sbjct: 392 RWGWPGVVALVTAMLACALLTAAWLWRR 419 >ZynfM [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 417 Score = 309 bits (791), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 171/419 (40%), Positives = 250/419 (59%), Gaps = 5/419 (1%) Query: 12 MQSVSDTSTTGSSALHGKPVKQPGTVLPRGAVRGSAAYRNIVLALFCSGFATFSLLYCVQ 71 M + +S + + QP + RG + + + LALF +G ATF+LLYCVQ Sbjct: 1 MSRTTTVDGAPASDTDKQSISQPNQFIKRG----TPQFMRVTLALFSAGLATFALLYCVQ 56 Query: 72 PLLPAFAQEFGIGAASASLALSLSTGFLAVSILLAGMVSERYGRKELMFASLATAACCNL 131 P+LP +QEFG+ A++S++LS+ST LA+ +L G +S+ GRK +M +L A+ C L Sbjct: 57 PILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKPVMVTALLLASICTL 116 Query: 132 LAGVAPNWELILVVRAVEGIALGGVPAVAMAYLAEEIDASGLGYAMGLYVGGNAFGGMVG 191 L+ + +W IL++RA+ G++L GV AV M YL+EEI S + ++MGLY+ GN+ GGM G Sbjct: 117 LSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAFSMGLYISGNSIGGMSG 176 Query: 192 RVAMSTMSEHIGWRHAMLVIGALDLALAVAFVLMLPASRNFVRNGTMQLRDHVALWKRHL 251 R+ ++ WR A+ IG LA A+ F +LP SR+F R +++ + ++ H Sbjct: 177 RLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHF-RPTSLRPKSLFINFRLHW 235 Query: 252 GHARLPLTFGIAALNMGIFATSYNYAGFRLMSPPFSLSATLTGLIFSAYIFGIVSSSWAG 311 LPL F L MG F T +NY G+RLM P+ +S + GL+ AY+ G SS AG Sbjct: 236 RDRGLPLLFAXGFLLMGSFVTLFNYIGYRLMLSPWHVSQAVVGLLSLAYLTGTWSSPKAG 295 Query: 312 SLADRYGRAPLVAAGIATSCAGLFLTCTSSLALVITGIVLLTIGFFTTHSAASSWVGRMA 371 ++ RYGR P++ GL +T SSL L+ G++L + GFF HS ASSW+G A Sbjct: 296 TMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGMLLFSAGFFAAHSVASSWIGPRA 355 Query: 372 SSGRGHAASLYLLSYYLGGSVLGSAGGWFWEHSGWNAVAAFMLLQVLTAAWLARRLWRQ 430 +G A+SLYL SYYLG S+ G+ GG FW + GWN V AF+ L ++ A + RL R+ Sbjct: 356 KRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNGVGAFIALMLVIALLVGTRLHRR 414 >ECs2302 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 417 Score = 308 bits (790), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 171/419 (40%), Positives = 250/419 (59%), Gaps = 5/419 (1%) Query: 12 MQSVSDTSTTGSSALHGKPVKQPGTVLPRGAVRGSAAYRNIVLALFCSGFATFSLLYCVQ 71 M + +S + + QP + RG + + + LALF +G ATF+LLYCVQ Sbjct: 1 MSRTTTVDGAPASDTDKQSISQPNQFIKRG----TPQFMRVTLALFSAGLATFALLYCVQ 56 Query: 72 PLLPAFAQEFGIGAASASLALSLSTGFLAVSILLAGMVSERYGRKELMFASLATAACCNL 131 P+LP +QEFG+ A++S++LS+ST LA+ +L G +S+ GRK +M +L A+ C L Sbjct: 57 PILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKPVMVTALLLASICTL 116 Query: 132 LAGVAPNWELILVVRAVEGIALGGVPAVAMAYLAEEIDASGLGYAMGLYVGGNAFGGMVG 191 L+ + +W IL++RA+ G++L GV AV M YL+EEI S + ++MGLY+ GN+ GGM G Sbjct: 117 LSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAFSMGLYISGNSIGGMSG 176 Query: 192 RVAMSTMSEHIGWRHAMLVIGALDLALAVAFVLMLPASRNFVRNGTMQLRDHVALWKRHL 251 R+ ++ WR A+ IG LA A+ F +LP SR+F R +++ + ++ H Sbjct: 177 RLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHF-RPTSLRPKSLFINFRLHW 235 Query: 252 GHARLPLTFGIAALNMGIFATSYNYAGFRLMSPPFSLSATLTGLIFSAYIFGIVSSSWAG 311 LPL F L MG F T +NY G+RLM P+ +S + GL+ AY+ G SS AG Sbjct: 236 RDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAVVGLLSLAYLTGTWSSPKAG 295 Query: 312 SLADRYGRAPLVAAGIATSCAGLFLTCTSSLALVITGIVLLTIGFFTTHSAASSWVGRMA 371 ++ RYGR P++ GL +T SSL L+ G++L + GFF HS ASSW+G A Sbjct: 296 TMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGMLLFSAGFFAAHSVASSWIGPRA 355 Query: 372 SSGRGHAASLYLLSYYLGGSVLGSAGGWFWEHSGWNAVAAFMLLQVLTAAWLARRLWRQ 430 +G A+SLYL SYYLG S+ G+ GG FW + GWN V AF+ L ++ A + RL R+ Sbjct: 356 KRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNGVGAFIALMLVIALLVGTRLHRR 414 >ynfM [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 417 Score = 308 bits (789), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 171/419 (40%), Positives = 250/419 (59%), Gaps = 5/419 (1%) Query: 12 MQSVSDTSTTGSSALHGKPVKQPGTVLPRGAVRGSAAYRNIVLALFCSGFATFSLLYCVQ 71 M + +S + + QP + RG + + + LALF +G ATF+LLYCVQ Sbjct: 1 MSRTTTVDGAPASDTDKQSISQPNQFIKRG----TPQFMRVTLALFSAGLATFALLYCVQ 56 Query: 72 PLLPAFAQEFGIGAASASLALSLSTGFLAVSILLAGMVSERYGRKELMFASLATAACCNL 131 P+LP +QEFG+ A++S++LS+ST LA+ +L G +S+ GRK +M +L A+ C L Sbjct: 57 PILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKPVMVTALLLASICTL 116 Query: 132 LAGVAPNWELILVVRAVEGIALGGVPAVAMAYLAEEIDASGLGYAMGLYVGGNAFGGMVG 191 L+ + +W IL++RA+ G++L GV AV M YL+EEI S + ++MGLY+ GN+ GGM G Sbjct: 117 LSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAFSMGLYISGNSIGGMSG 176 Query: 192 RVAMSTMSEHIGWRHAMLVIGALDLALAVAFVLMLPASRNFVRNGTMQLRDHVALWKRHL 251 R+ ++ WR A+ IG LA A+ F +LP SR+F R +++ + ++ H Sbjct: 177 RLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHF-RPTSLRPKTLFINFRLHW 235 Query: 252 GHARLPLTFGIAALNMGIFATSYNYAGFRLMSPPFSLSATLTGLIFSAYIFGIVSSSWAG 311 LPL F L MG F T +NY G+RLM P+ +S + GL+ AY+ G SS AG Sbjct: 236 RDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAVVGLLSLAYLTGTWSSPKAG 295 Query: 312 SLADRYGRAPLVAAGIATSCAGLFLTCTSSLALVITGIVLLTIGFFTTHSAASSWVGRMA 371 ++ RYGR P++ GL +T SSL L+ G++L + GFF HS ASSW+G A Sbjct: 296 TMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGMLLFSAGFFAAHSVASSWIGPRA 355 Query: 372 SSGRGHAASLYLLSYYLGGSVLGSAGGWFWEHSGWNAVAAFMLLQVLTAAWLARRLWRQ 430 +G A+SLYL SYYLG S+ G+ GG FW + GWN V AF+ L ++ A + RL R+ Sbjct: 356 KRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNGVGAFIALMLVIALLVGTRLHRR 414 >PA5030 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 438 Score = 294 bits (752), Expect = 3e-79, Method: Compositional matrix adjust. Identities = 165/405 (40%), Positives = 246/405 (60%), Gaps = 1/405 (0%) Query: 9 RIAMQSVSDTSTTGSSALHGKPVKQPGTVLPRGAVRGSAAYRNIVLALFCSGFATFSLLY 68 ++ Q+ + + ++ V + T + R +G+ + LALF GFATF+LLY Sbjct: 5 QVRPQAEEEPALIEAAREAANEVLEAATEVERYIEKGTPQFMRTSLALFSGGFATFALLY 64 Query: 69 CVQPLLPAFAQEFGIGAASASLALSLSTGFLAVSILLAGMVSERYGRKELMFASLATAAC 128 C+QP++P ++ F I AA +SLALS++T LA+ +L+ G +S+ GRK +M SL AA Sbjct: 65 CIQPMMPVLSKAFSISAAESSLALSVATAMLALGLLVTGPISDAIGRKPVMVVSLLAAAL 124 Query: 129 CNLLAGVAPNWELILVVRAVEGIALGGVPAVAMAYLAEEIDASGLGYAMGLYVGGNAFGG 188 L + V P W +L++RA+ G++L G+ AVAM YL+EEI +G +MGLY+GGNA GG Sbjct: 125 FTLGSAVMPTWHGVLLMRALVGLSLSGLAAVAMTYLSEEIHPQHIGLSMGLYIGGNAIGG 184 Query: 189 MVGRVAMSTMSEHIGWRHAMLVIGALDLALAVAFVLMLPASRNFVRNGTMQLRDHVALWK 248 M GR+ + + I W A+ V+G L L A+ F +LP S++F R ++ + ++ Sbjct: 185 MSGRLISGVLVDFISWHAALAVLGGLALVAALVFWRVLPESKHF-RPAPLKPATLLNGYR 243 Query: 249 RHLGHARLPLTFGIAALNMGIFATSYNYAGFRLMSPPFSLSATLTGLIFSAYIFGIVSSS 308 H A LP F I L MG F T +NY G+RL++ P+ +S + G++ Y+ GI SS+ Sbjct: 244 LHFRDAGLPWLFLIGFLLMGSFVTLFNYIGYRLLAEPYHMSQAVVGVLSVVYLSGIYSSA 303 Query: 309 WAGSLADRYGRAPLVAAGIATSCAGLFLTCTSSLALVITGIVLLTIGFFTTHSAASSWVG 368 W GSLAD+ GR ++ A I GL LT + L++ G++L T GFF HS ASSW+G Sbjct: 304 WVGSLADKLGRRKVLWAVILLMLGGLLLTLFEPIPLMLAGLLLFTFGFFGAHSVASSWIG 363 Query: 369 RMASSGRGHAASLYLLSYYLGGSVLGSAGGWFWEHSGWNAVAAFM 413 R A +G A+SLYL SYY+G S+ G+ GG FW + GWN + F+ Sbjct: 364 RRALRAKGQASSLYLFSYYVGSSLAGTLGGVFWHYYGWNGIGLFI 408