BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0395.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0820 [K] COG0583 Transcriptional regulator Bme Brucella mel... 241 2e-63 STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 238 1e-62 DRA0336 [K] COG0583 Transcriptional regulator Dra Deinococcus ra... 230 2e-60 YPO1929 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 221 1e-57 PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 185 9e-47 >BMEII0820 [K] COG0583 Transcriptional regulator Bme Brucella melitensis Length = 299 Score = 241 bits (614), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 136/273 (49%), Positives = 179/273 (65%) Query: 1 MELRHLRYFLAVAEQRSFTRAAEKVGIGQPPLSMQIKDLEAEIGGALFLRTSHGVELSEV 60 MELRHLRYFLAVAE+ +FTRAA K+GIGQPPLS QI+DLE EIG LF R HG EL+ Sbjct: 5 MELRHLRYFLAVAEEGNFTRAAAKLGIGQPPLSQQIRDLENEIGVMLFHRVPHGAELTAA 64 Query: 61 GRVFLPHAQKAVDGAEQALRAAQQAASGEVGLLRMGFTSSAVFHPLVSHALQQFRERHRK 120 G FL A + +E+A AAQ+AA GE G L +GFT+S+ F+P+VS A++ FR + + Sbjct: 65 GAAFLEEATATIASSEKAKLAAQRAARGESGRLSLGFTASSAFNPIVSGAIRHFRAKWPE 124 Query: 121 LEISLSEGITEQLLADIAASQLDAAFVRIVTTPSAELGVVELPAEKLKVALPRSHPLARR 180 +E+ L+E T L+ + +LD AF+R A + + L E + VALP H LA Sbjct: 125 VELFLTEMNTNLLIERLVRGELDTAFIRPGLEDPANVRMKRLADEPMLVALPSHHRLAVY 184 Query: 181 KSLHLQDLAGENFIMVPRGKGSALYDNIFSACQAAGFDPQVIQLAPQLTSAINLVAAGLG 240 + L L LAGE F++ PR G +LYD+I +AC+ AGF+ V Q APQ+ S +NLVAA LG Sbjct: 185 ERLPLSALAGEPFVLFPRIVGLSLYDDIAAACRMAGFEMNVTQEAPQMPSVVNLVAANLG 244 Query: 241 ISIVPEAIEQVQLAQVRYIDIREPAPRAQLSLA 273 +SIVP AI Q++L V Y I A+L+LA Sbjct: 245 VSIVPAAIAQIRLDGVTYRPIEGEPLVARLALA 277 >STM3121 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 292 Score = 238 bits (606), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 126/276 (45%), Positives = 177/276 (64%) Query: 1 MELRHLRYFLAVAEQRSFTRAAEKVGIGQPPLSMQIKDLEAEIGGALFLRTSHGVELSEV 60 MELRH+RYFLAVAE+R FTRAA K+GIGQPPLS QIKDLE E+G LF R HG EL+E Sbjct: 1 MELRHIRYFLAVAEERHFTRAATKLGIGQPPLSQQIKDLERELGAQLFRRVPHGAELTEA 60 Query: 61 GRVFLPHAQKAVDGAEQALRAAQQAASGEVGLLRMGFTSSAVFHPLVSHALQQFRERHRK 120 G+ F + A +A+ AAQ+ A GE G+LR+GFT+SA F+ +V A++ F+ + Sbjct: 61 GKAFYDVVKGMPATATRAVLAAQRVARGESGVLRVGFTASAAFNSVVPGAIRTFKRAYPD 120 Query: 121 LEISLSEGITEQLLADIAASQLDAAFVRIVTTPSAELGVVELPAEKLKVALPRSHPLARR 180 + + L EG T QL ++ LD AF+R T + + L E + + L +HP A Sbjct: 121 VRLQLEEGNTTQLADELNEGSLDVAFLRPGFTGNERFQLRLLSEEPMVIVLAETHPAAAC 180 Query: 181 KSLHLQDLAGENFIMVPRGKGSALYDNIFSACQAAGFDPQVIQLAPQLTSAINLVAAGLG 240 K + L L E F++ PR G +LYD + AC AGF+P++ QL PQ++S INLV+A +G Sbjct: 181 KQIALSILKDEFFLLFPREIGLSLYDAVIKACGKAGFEPKIGQLVPQISSVINLVSAEMG 240 Query: 241 ISIVPEAIEQVQLAQVRYIDIREPAPRAQLSLAYHR 276 +S+VP+++ QV + V Y + + P A+L+LAY R Sbjct: 241 VSMVPDSMRQVNVKGVVYRPVADQMPVAKLALAYRR 276 >DRA0336 [K] COG0583 Transcriptional regulator Dra Deinococcus radiodurans Length = 316 Score = 230 bits (587), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 122/282 (43%), Positives = 177/282 (62%) Query: 1 MELRHLRYFLAVAEQRSFTRAAEKVGIGQPPLSMQIKDLEAEIGGALFLRTSHGVELSEV 60 MELRHLRYFLAVA++R+ TRAA ++GI QPPLS QI++LE EIG LF R GVEL+E Sbjct: 17 MELRHLRYFLAVADERNVTRAAARLGIQQPPLSQQIRELEREIGTPLFHRVPRGVELTEA 76 Query: 61 GRVFLPHAQKAVDGAEQALRAAQQAASGEVGLLRMGFTSSAVFHPLVSHALQQFRERHRK 120 G FL Q E A A++A GE G LR+GFT +A +P V L+++R+ + Sbjct: 77 GHTFLRLVQSIPAQVEGATHEARRAGRGETGELRVGFTGAASINPQVQGLLRRYRDLYPD 136 Query: 121 LEISLSEGITEQLLADIAASQLDAAFVRIVTTPSAELGVVELPAEKLKVALPRSHPLARR 180 + ++L+E T LL ++ + QLDA R + +L + + E + +PR HP A+ Sbjct: 137 VRLTLTEKNTVTLLDELRSHQLDAVLARPLPQHLGDLTLTLVAREPMVAVVPRGHPAAQT 196 Query: 181 KSLHLQDLAGENFIMVPRGKGSALYDNIFSACQAAGFDPQVIQLAPQLTSAINLVAAGLG 240 + L L+ L E FI PR G +YD ++ AC+AAGF+P++ QLAPQ+ S ++LVAAGLG Sbjct: 197 RPLPLERLRDETFITTPREFGPLIYDTVWQACRAAGFEPRLGQLAPQMLSIVSLVAAGLG 256 Query: 241 ISIVPEAIEQVQLAQVRYIDIREPAPRAQLSLAYHRQSIAAS 282 +S+VP+A+ ++ L Y+++R P P L+L AA+ Sbjct: 257 VSLVPDAMRRLNLEGCEYLELRPPVPTVDLTLLCRPHERAAT 298 >YPO1929 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 292 Score = 221 bits (564), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 125/276 (45%), Positives = 177/276 (64%) Query: 1 MELRHLRYFLAVAEQRSFTRAAEKVGIGQPPLSMQIKDLEAEIGGALFLRTSHGVELSEV 60 MELRH+RYFLAVAE+R FTRAA ++GIGQPPLS QIKDLE E+G LF R S+G EL+E Sbjct: 1 MELRHIRYFLAVAEERHFTRAAARLGIGQPPLSQQIKDLERELGALLFRRVSYGAELTEA 60 Query: 61 GRVFLPHAQKAVDGAEQALRAAQQAASGEVGLLRMGFTSSAVFHPLVSHALQQFRERHRK 120 G FL ++ AE+A +AAQ+A GE+G+LR+GFT+S+ F+ +V A++ FR + Sbjct: 61 GIAFLDVVKEIPVMAERAAQAAQRAVRGELGVLRVGFTASSAFNSVVPTAIRAFRRAYPD 120 Query: 121 LEISLSEGITEQLLADIAASQLDAAFVRIVTTPSAELGVVELPAEKLKVALPRSHPLARR 180 + + L E T +L + LD AF+R S + L E + + + +HP A Sbjct: 121 VRLQLEEDNTTRLADGLNEGSLDVAFLRPGFAGSERFHLRMLSEEPMMIVMAENHPAASY 180 Query: 181 KSLHLQDLAGENFIMVPRGKGSALYDNIFSACQAAGFDPQVIQLAPQLTSAINLVAAGLG 240 + + L E F++ PR G LYD++ +C+ AGF+P + QLAPQ+ S INLVAA +G Sbjct: 181 EEISLSAFRDETFLLFPREIGLTLYDSVIESCRTAGFEPTIGQLAPQIASVINLVAAEMG 240 Query: 241 ISIVPEAIEQVQLAQVRYIDIREPAPRAQLSLAYHR 276 +SIVP ++ QV++ V Y I + P A+L+LAY R Sbjct: 241 VSIVPASMSQVKVIGVVYRHIADQTPTAKLALAYRR 276 >PA5029 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 301 Score = 185 bits (470), Expect = 9e-47, Method: Compositional matrix adjust. Identities = 107/266 (40%), Positives = 160/266 (60%), Gaps = 3/266 (1%) Query: 1 MELRHLRYFLAVAEQRSFTRAAEKVGIGQPPLSMQIKDLEAEIGGALFLRTSHGVELSEV 60 MELRHLRYF+AVAE+ F RAAE++GI QPPLS QI+ LE EIG LF RT+ VEL++ Sbjct: 1 MELRHLRYFIAVAEELHFGRAAERLGISQPPLSQQIQALEEEIGARLFERTNRRVELTDA 60 Query: 61 GRVFLPHAQKAVDGAEQALRAAQQAASGEVGLLRMGFTSSAVFHPLVSHALQQFRERHRK 120 GR+FL +++ + ++A+ A++A GE+G L++GFTSSA F + ++ FR+ + Sbjct: 61 GRLFLDESRQVLAQVDKAVLLARRAHLGELGELKIGFTSSAPFTSTIPSSIHAFRKAYPD 120 Query: 121 LEISLSEGITEQLLADIAASQLDAAFVRIVTTPSAELGVVELPAEKLKVALPRSHPLA-- 178 + + L E + Q+L + L +R + P A + VEL E L L HPLA Sbjct: 121 VHLDLQEMSSRQVLKALLEESLQVGVIRPLALPDA-VHWVELFREPLVAVLRADHPLAAG 179 Query: 179 RRKSLHLQDLAGENFIMVPRGKGSALYDNIFSACQAAGFDPQVIQLAPQLTSAINLVAAG 238 L + LA E F+ PR G+ LYD + + + AGF P++ Q A + + I LV+AG Sbjct: 180 SEDGLAIAALAEEPFVFFPRSYGTGLYDQVIALTRQAGFSPRIAQEASEAMTIIGLVSAG 239 Query: 239 LGISIVPEAIEQVQLAQVRYIDIREP 264 LG+SI+P + + ++ V Y + +P Sbjct: 240 LGVSILPASFRRTRVDGVVYRTLSDP 265