BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0382.p (660 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3164 [R] COG0457 FOG Rso Ralstonia solanacearum 218 5e-56 FN1787 [R] COG0457 FOG Fnu Fusobacterium nucleatum 111 6e-24 CC1457 [R] COG0457 FOG Ccr Caulobacter vibrioides 105 4e-22 MTH83 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus 101 6e-21 MTH72 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus 96 3e-19 >RSc3164 [R] COG0457 FOG Rso Ralstonia solanacearum Length = 387 Score = 218 bits (554), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 140/375 (37%), Positives = 192/375 (51%), Gaps = 14/375 (3%) Query: 280 RFDDAMRMFKQALALDPKHALTYNNIGAIQHDHGDYDDALGNFRTALALRPNYPTAKHNL 339 RF++A + + LA + + + A G + +A P A+ +L Sbjct: 24 RFEEAEALVRPPLASGSGPLVLWKLLAAALRPQGRIAETRAIQEMLVAHAPGDFPARFDL 83 Query: 340 ALTLLLRGQFEEGWECHESRLTTKERAHVYRLIHKLFEVIPKWDGKSSLAGKRILLMHEQ 399 + TLLL G+FE GW + R + A + R + + P+W G+ + G+ +L+ EQ Sbjct: 84 SETLLLLGEFERGWREYRYRYSLAHTAAIERKVQR-----PRWSGQP-IPGQTLLIHDEQ 137 Query: 400 GFGDSIQFLRYARLL-MEQGASVALHVKNPLYRLFQSFTPAVTLVRESDPLPPCDCAYVL 458 GFGD+ QFLR GA V L V L + T +V PP D L Sbjct: 138 GFGDTFQFLRMVPWAKARSGARVILEVNAETLSLARRSTGFDHIVARGSLPPPFDAHCEL 197 Query: 459 MSLPYALRTHSVEDIPRYAEGYLSADASLAAHWKQKISTLTRSADNLRVGIVWGGNPEHG 518 MSLP A+ D+P YLSAD A W+Q+++ L R V +VW G P H Sbjct: 198 MSLPMAMGLKP-SDLPGPVP-YLSADPLRIAQWQQRLAGLPRPL----VALVWAGRPTHF 251 Query: 519 NDRHRSIPLEKVKQLFEIPRMEFYSLQKGKPADGLKELPTDWPVFDLGNECQDFADTAAA 578 ND +RS+ L ++ L P F S+QKG A + P + L ++ DF DTAA Sbjct: 252 NDANRSLTLARLAPLAH-PGATFLSIQKGPAAAQSADPPPGMSLVPLSDDILDFEDTAAI 310 Query: 579 ISNLDLVICVDTSVAHLAGALGHPTWVLLPHVPDWRWLNDRDDSPWYPGMRLFRQPAVSD 638 +S DL+I VD++ HLAGALG P WV+LP VPDWRWL +R D+PWYPGMRLFRQ A + Sbjct: 311 LSIADLLISVDSAPVHLAGALGRPVWVMLPFVPDWRWLLERTDTPWYPGMRLFRQHARGN 370 Query: 639 WDSVLKKVGEELTLL 653 WD VL + EL L Sbjct: 371 WDGVLSAMAGELARL 385 >FN1787 [R] COG0457 FOG Fnu Fusobacterium nucleatum Length = 628 Score = 111 bits (277), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 75/303 (24%), Positives = 148/303 (48%), Gaps = 1/303 (0%) Query: 50 TAVLARAPNLVFANHARGLIAMQEGQFAQAEQYLRKAIEADPNNAEYLSNLAGTVLSQDR 109 T + + PN + RGL ++ +A +AIE + NNA Y N A + ++ Sbjct: 17 TEKIEKEPNNDIYYNNRGLSYFLLKKYEEAINDYNRAIELNLNNASYYYNRACSYYCSNK 76 Query: 110 IDESIAIYERAIAIDKENRAARIGLANALHEKNDPEASIKYFEDAARREPNAPGPLSHLG 169 D++I Y++AI ++ + ++ N +I+ ++ A + +PN G Sbjct: 77 YDKAIEDYDKAIKLNPNDACYFNNRGHSYFALNKYSEAIEDYDKAIKLDPNNASYYYKRG 136 Query: 170 RALIDARRFDEAVATILKSLEYQINFAPSHTALGEAFHAMEMYKEAVESHKTAILLDPQD 229 + ++D+A+ K+++ N A ++ G+ ++ + Y +++E + AI LDP + Sbjct: 137 FSYYALNKYDKAIEDYNKAIKLDPNNAAYFSSRGDIYYYEKAYNKSIEDYNKAIKLDPNN 196 Query: 230 TYAHNKIADSYLKINKIDEAHEHLLRVIEIAPKDPNGYVKLGSSYFNTGDRFDDAMRMFK 289 + ++ +Y K+ K EA + I++ P + G +Y N ++ +A+ + Sbjct: 197 AFYYDNRGLAYEKLKKYKEAINDYNKAIKLNPNNAFYCYNRGFTY-NKLKKYKEAINDYD 255 Query: 290 QALALDPKHALTYNNIGAIQHDHGDYDDALGNFRTALALRPNYPTAKHNLALTLLLRGQF 349 +A+ LDP +A +NN G ++ G+Y AL ++ A+ L PNY A +N +T G+F Sbjct: 256 KAIKLDPNNASYFNNRGVAYNNLGEYSKALEDYDKAIKLNPNYTFAYNNKGITFDNLGEF 315 Query: 350 EEG 352 EE Sbjct: 316 EEA 318 Score = 101 bits (251), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 66/260 (25%), Positives = 134/260 (51%), Gaps = 3/260 (1%) Query: 85 KAIEADPNNAEYLSNLAGTVLSQDRIDESIAIYERAIAIDKENRAARIGLANALHEKNDP 144 KAI+ +PN+A Y +N + + ++ E+I Y++AI +D N + + + N Sbjct: 86 KAIKLNPNDACYFNNRGHSYFALNKYSEAIEDYDKAIKLDPNNASYYYKRGFSYYALNKY 145 Query: 145 EASIKYFEDAARREPNAPGPLSHLGRALIDARRFDEAVATILKSLEYQINFAPSHTALGE 204 + +I+ + A + +PN S G + +++++ K+++ N A + G Sbjct: 146 DKAIEDYNKAIKLDPNNAAYFSSRGDIYYYEKAYNKSIEDYNKAIKLDPNNAFYYDNRGL 205 Query: 205 AFHAMEMYKEAVESHKTAILLDPQDT-YAHNKIADSYLKINKIDEAHEHLLRVIEIAPKD 263 A+ ++ YKEA+ + AI L+P + Y +N+ +Y K+ K EA + I++ P + Sbjct: 206 AYEKLKKYKEAINDYNKAIKLNPNNAFYCYNR-GFTYNKLKKYKEAINDYDKAIKLDPNN 264 Query: 264 PNGYVKLGSSYFNTGDRFDDAMRMFKQALALDPKHALTYNNIGAIQHDHGDYDDALGNFR 323 + + G +Y N G+ + A+ + +A+ L+P + YNN G + G++++A+ N+ Sbjct: 265 ASYFNNRGVAYNNLGE-YSKALEDYDKAIKLNPNYTFAYNNKGITFDNLGEFEEAIMNYN 323 Query: 324 TALALRPNYPTAKHNLALTL 343 A+ L P+Y +A N +L Sbjct: 324 KAIELDPSYKSAIENRNFSL 343 >CC1457 [R] COG0457 FOG Ccr Caulobacter vibrioides Length = 596 Score = 105 bits (262), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 127/512 (24%), Positives = 206/512 (40%), Gaps = 73/512 (14%) Query: 183 ATILKSLEYQINFAPSHTA----LGEAFHAMEMYKEAVESHKTAILLDPQDTYAHNKIAD 238 A+ L++ E + P H LG M M + A + L P D N +A Sbjct: 108 ASSLRAYEAALALLPDHGPVAGDLGRLAFRMNMPELAAKFFAHYRLARPDDVEGANNLAC 167 Query: 239 SYLKINKIDEAHEHLLRVIEIAPKDPNGYVKLGSSYFNTGDRFDDAMRMFKQALALDPKH 298 + ++N+ EA E L + P+ + LG+ N GD ++ F ++L L P Sbjct: 168 ALRELNRESEAIEVLKAALGANPEAAVLWNTLGTVLCNIGDA-AGSIVFFDESLRLAPDF 226 Query: 299 ALTYNNIGAIQHDHGDYDDALGNFRTALALRPNYPTAKHNLAL-------TLLLRGQFEE 351 + Y+N + D G+ + AL + A+ P + +LA+ LL G+ E Sbjct: 227 SKAYHNRAFARLDLGEIEAALADCEAAM----RSPGSPEDLAMMQFARATILLALGRVGE 282 Query: 352 GWECHESRLTTKERAHVYRLIHKLFEVIPKWDGKSSLAGKRILLMHEQGFGDSIQFLRYA 411 GWE +ESR + I + +W G+ L GKR+++ EQG GD + F Sbjct: 283 GWEAYESRFSPALSDAPRFQIPGV-----RWSGQD-LRGKRLMITTEQGLGDEVMFANML 336 Query: 412 RLLMEQ---GASVALHVKNPLYRLFQSFTPAVTLVRESDPLPPCDCAY---VLMSLPY-- 463 ++E ++L V+ L LF+ P V + AY V + PY Sbjct: 337 PDIVEALGPDGFLSLAVERRLAPLFERTFPKVEVTAHR------TIAYEGRVFRAAPYIE 390 Query: 464 ----------------ALRTHSVEDIPRYAEGYLSADASLAAHWKQKISTLTRSADNLRV 507 +LR + E P+ +L D + AHWK ++ L +V Sbjct: 391 NWDRFDYWAAIGDFLPSLRP-TAEAFPKR-NAFLQPDPARVAHWKAQLEKL---GPGPKV 445 Query: 508 GIVWGGNPEHGNDRHRSIPLEKVKQLFEIPRMEFYSLQKGKPADGLKELPTDWPVFDLGN 567 G++W + + P + + P + F +LQ G D +E+ + +LG Sbjct: 446 GLLWKSLKLNAERARQFSPFHLWEPVLHTPGVVFVNLQYG---DCEEEIA--FAKEELGV 500 Query: 568 EC---------QDFADTAAAISNLDLVICVDTSVAHLAGALGHPTWVLLPHVPDWRWLND 618 E D D AA + +DLVI + +LAGA+G P + +L W L Sbjct: 501 EIWQPEGIDLKADLDDVAALCAAVDLVIGFSNATINLAGAVGTPIF-MLTGASSWTRLGT 559 Query: 619 RDDSPWYPGMRLFRQPAVSDWDSVLKKVGEEL 650 + PWYP +R F W+ + +V L Sbjct: 560 -EYYPWYPSVRCFVTEQYGVWEPTMGRVATAL 590 >MTH83 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus Length = 379 Score = 101 bits (251), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 80/330 (24%), Positives = 150/330 (45%), Gaps = 35/330 (10%) Query: 65 ARGLIAMQEGQFAQAEQYLRKAIEADPNNAEYLSNLAGTVLSQDRIDESIAIYERAIAID 124 A G ++++G++ +A + RKA++A PNN E L A T+L R ++++ YE+ + + Sbjct: 21 AGGRSSLKQGKYKEALKEFRKALKARPNNPEILHYNAITLLKLKRPEKALECYEKILKNN 80 Query: 125 KENRAARIGLANALHEKNDPEASIKYFEDAARREPNAPGPLSHLGRALIDARRFDEAVAT 184 + A L E + +++ +E A + P G ++ L + R+DEA+ Sbjct: 81 PKLAEAWNNKGLVLKELGRYDEALECYEKALKINPKYAGAWNNKALVLKELGRYDEALEC 140 Query: 185 ILKSL------------------------------EYQINFAPSH----TALGEAFHAME 210 K+L E I P + G H ++ Sbjct: 141 YEKALQINPKLADAWYNKGSVLIYLKKYKKALKCFEKAIELNPKNYRAWGTKGITLHNLK 200 Query: 211 MYKEAVESHKTAILLDPQDTYAHNKIADSYLKINKIDEAHEHLLRVIEIAPKDPNGYVKL 270 +Y+EA++ + + L+PQD A N + ++ + DE+ E + ++I PK + Sbjct: 201 IYEEALKCYDKVLQLNPQDDKAWNNKGLVFNELGRYDESLECYEKALQINPKLAEAWNNK 260 Query: 271 GSSYFNTGDRFDDAMRMFKQALALDPKHALTYNNIGAIQHDHGDYDDALGNFRTALALRP 330 G G R+++A+ +++AL +DP+ T+NN G + + G Y DAL F+ AL + P Sbjct: 261 GVVLSELG-RYEEALECYEKALEIDPEDDKTWNNKGLVLEELGKYKDALECFQKALEINP 319 Query: 331 NYPTAKHNLALTLLLRGQFEEGWECHESRL 360 + A + L + EE +C++ L Sbjct: 320 EFADAWKWKGIILEDLKKPEESLKCYKKAL 349 >MTH72 [R] COG0457 FOG Mth Methanothermobacter thermautotrophicus Length = 403 Score = 95.9 bits (237), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 72/294 (24%), Positives = 145/294 (49%), Gaps = 1/294 (0%) Query: 67 GLIAMQEGQFAQAEQYLRKAIEADPNNAEYLSNLAGTVLSQDRIDESIAIYERAIAIDKE 126 G ++++G++ +A + RKA++A PN+ E L A T+L R ++++ YE+ + + + Sbjct: 23 GRSSLKQGKYKEALKEFRKALKASPNDPEILHYNAMTLLKLKRPEKALKCYEKILKNNPK 82 Query: 127 NRAARIGLANALHEKNDPEASIKYFEDAARREPNAPGPLSHLGRALIDARRFDEAVATIL 186 A L E + +++ +E A + +P G ++ G L + ++A+ Sbjct: 83 LAEAWNNKGVVLKELKRYDEALECYERALQIDPQDDGTWNNKGALLDTIGKPEKAIECYE 142 Query: 187 KSLEYQINFAPSHTALGEAFHAMEMYKEAVESHKTAILLDPQDTYAHNKIADSYLKINKI 246 K+LE A + G ++ Y+EA+E ++ A+ ++ + A A + ++ + Sbjct: 143 KALEINQKNAKAWYNKGNGLRSLGKYEEALECYEKALQINAEFVEAWYNKALIFEELKRY 202 Query: 247 DEAHEHLLRVIEIAPKDPNGYVKLGSSYFNTGDRFDDAMRMFKQALALDPKHALTYNNIG 306 DEA E R ++I P+D + G + +T + + A+ +++AL ++ K+A +NN G Sbjct: 203 DEALECYGRALQIDPQDDGTWNNKG-ALLDTIGKPEKAIECYEKALEINQKNAKAWNNKG 261 Query: 307 AIQHDHGDYDDALGNFRTALALRPNYPTAKHNLALTLLLRGQFEEGWECHESRL 360 + + YD+AL + AL + N + L G++EE EC E L Sbjct: 262 VVLEELKRYDEALECYEKALEINLENDETWANKGVLLRKLGKYEEALECFEKAL 315 Score = 84.0 bits (206), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 81/366 (22%), Positives = 157/366 (42%), Gaps = 42/366 (11%) Query: 1 MSTRKSSNKHGKHIPAPAAAKSNLQ------DLLDVRKCLDLLDNRKTEEAKTICTAVLA 54 +S +SS K GK+ A + L+ ++L + LL ++ E+A +L Sbjct: 20 LSGGRSSLKQGKYKEALKEFRKALKASPNDPEILHYN-AMTLLKLKRPEKALKCYEKILK 78 Query: 55 RAPNLVFANHARGLIAMQEGQFAQAEQYLRKAIEADPNNAEYLSNLAGTVLSQDRIDESI 114 P L A + +G++ + ++ +A + +A++ DP + +N + + + +++I Sbjct: 79 NNPKLAEAWNNKGVVLKELKRYDEALECYERALQIDPQDDGTWNNKGALLDTIGKPEKAI 138 Query: 115 AIYERAIAIDKENRAARIGLANALHEKNDPEASIKYFEDAARREPNAPGPLSHLGRALID 174 YE+A+ I+++N A N L LG Sbjct: 139 ECYEKALEINQKNAKAWYNKGNGLR---------------------------SLG----- 166 Query: 175 ARRFDEAVATILKSLEYQINFAPSHTALGEAFHAMEMYKEAVESHKTAILLDPQDTYAHN 234 +++EA+ K+L+ F + F ++ Y EA+E + A+ +DPQD N Sbjct: 167 --KYEEALECYEKALQINAEFVEAWYNKALIFEELKRYDEALECYGRALQIDPQDDGTWN 224 Query: 235 KIADSYLKINKIDEAHEHLLRVIEIAPKDPNGYVKLGSSYFNTGDRFDDAMRMFKQALAL 294 I K ++A E + +EI K+ + G R+D+A+ +++AL + Sbjct: 225 NKGALLDTIGKPEKAIECYEKALEINQKNAKAWNNKGVV-LEELKRYDEALECYEKALEI 283 Query: 295 DPKHALTYNNIGAIQHDHGDYDDALGNFRTALALRPNYPTAKHNLALTLLLRGQFEEGWE 354 + ++ T+ N G + G Y++AL F AL + P + A + L + EE + Sbjct: 284 NLENDETWANKGVLLRKLGKYEEALECFEKALEINPEFADAWEWKGIILEDLKKPEEALK 343 Query: 355 CHESRL 360 C+E L Sbjct: 344 CYEKAL 349 Score = 72.0 bits (175), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 53/219 (24%), Positives = 101/219 (46%), Gaps = 1/219 (0%) Query: 147 SIKYFEDAARREPNAPGPLSHLGRALIDARRFDEAVATILKSLEYQINFAPSHTALGEAF 206 ++K F A + PN P L + L+ +R ++A+ K L+ A + G Sbjct: 35 ALKEFRKALKASPNDPEILHYNAMTLLKLKRPEKALKCYEKILKNNPKLAEAWNNKGVVL 94 Query: 207 HAMEMYKEAVESHKTAILLDPQDTYAHNKIADSYLKINKIDEAHEHLLRVIEIAPKDPNG 266 ++ Y EA+E ++ A+ +DPQD N I K ++A E + +EI K+ Sbjct: 95 KELKRYDEALECYERALQIDPQDDGTWNNKGALLDTIGKPEKAIECYEKALEINQKNAKA 154 Query: 267 YVKLGSSYFNTGDRFDDAMRMFKQALALDPKHALTYNNIGAIQHDHGDYDDALGNFRTAL 326 + G+ + G ++++A+ +++AL ++ + + N I + YD+AL + AL Sbjct: 155 WYNKGNGLRSLG-KYEEALECYEKALQINAEFVEAWYNKALIFEELKRYDEALECYGRAL 213 Query: 327 ALRPNYPTAKHNLALTLLLRGQFEEGWECHESRLTTKER 365 + P +N L G+ E+ EC+E L ++ Sbjct: 214 QIDPQDDGTWNNKGALLDTIGKPEKAIECYEKALEINQK 252 Score = 65.1 bits (157), Expect = 5e-10, Method: Compositional matrix adjust. Identities = 57/239 (23%), Positives = 107/239 (44%), Gaps = 7/239 (2%) Query: 60 VFANHARGLIAMQEGQFAQAEQYLRKAIEADPNNAEYLSNLAGTVLSQDRIDESIAIYER 119 + N GL ++ G++ +A + KA++ + E N A R DE++ Y R Sbjct: 154 AWYNKGNGLRSL--GKYEEALECYEKALQINAEFVEAWYNKALIFEELKRYDEALECYGR 211 Query: 120 AIAIDKENRAARIGLANALHEKNDPEASIKYFEDAARREPNAPGPLSHLGRALIDARRFD 179 A+ ID ++ L PE +I+ +E A ++ G L + +R+D Sbjct: 212 ALQIDPQDDGTWNNKGALLDTIGKPEKAIECYEKALEINQKNAKAWNNKGVVLEELKRYD 271 Query: 180 EAVATILKSLEYQINFAPSHTALGEAFHAMEMYKEAVESHKTAILLDPQ--DTYAHNKIA 237 EA+ K+LE + + G + Y+EA+E + A+ ++P+ D + I Sbjct: 272 EALECYEKALEINLENDETWANKGVLLRKLGKYEEALECFEKALEINPEFADAWEWKGII 331 Query: 238 DSYLKINKIDEAHEHLLRVIEIAPKDPNGYVKLGSSYFNTGDRFDDAMRMFKQALALDP 296 LK K +EA + + +++ P+D + G + G + A + +K+AL +DP Sbjct: 332 LEDLK--KPEEALKCYEKALKLNPQDKTLWYMQGKTLQKLG-KHQKAKKSYKKALKIDP 387 Score = 62.8 bits (151), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 58/259 (22%), Positives = 120/259 (46%), Gaps = 5/259 (1%) Query: 74 GQFAQAEQYLRKAIEADPNNAEYLSNLAGTVLSQDRIDESIAIYERAIAIDKENRAARIG 133 G+ +A + KA+E + NA+ N + S + +E++ YE+A+ I+ E A Sbjct: 132 GKPEKAIECYEKALEINQKNAKAWYNKGNGLRSLGKYEEALECYEKALQINAEFVEAWYN 191 Query: 134 LANALHEKNDPEASIKYFEDAARREPNAPGPLSHLGRALIDARRFDEAVATILKSLEYQI 193 A E + +++ + A + +P G ++ G L + ++A+ K+LE Sbjct: 192 KALIFEELKRYDEALECYGRALQIDPQDDGTWNNKGALLDTIGKPEKAIECYEKALEINQ 251 Query: 194 NFAPSHTALGEAFHAMEMYKEAVESHKTA--ILLDPQDTYAHNKIADSYLKINKIDEAHE 251 A + G ++ Y EA+E ++ A I L+ +T+A+ + K+ K +EA E Sbjct: 252 KNAKAWNNKGVVLEELKRYDEALECYEKALEINLENDETWANKGVL--LRKLGKYEEALE 309 Query: 252 HLLRVIEIAPKDPNGYVKLGSSYFNTGDRFDDAMRMFKQALALDPKHALTYNNIGAIQHD 311 + +EI P+ + + G + ++A++ +++AL L+P+ + G Sbjct: 310 CFEKALEINPEFADAWEWKG-IILEDLKKPEEALKCYEKALKLNPQDKTLWYMQGKTLQK 368 Query: 312 HGDYDDALGNFRTALALRP 330 G + A +++ AL + P Sbjct: 369 LGKHQKAKKSYKKALKIDP 387