BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0293.p (453 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1647 [T] COG0642 Signal transduction histidine kinase Rso Ral... 417 e-116 VC2713 [T] COG0642 Signal transduction histidine kinase Vch Vibr... 180 7e-45 envZ [T] COG0642 Signal transduction histidine kinase Eco Escher... 160 4e-39 ZenvZ [T] COG0642 Signal transduction histidine kinase EcZ Esche... 160 4e-39 ECs4246 [T] COG0642 Signal transduction histidine kinase Ecs Esc... 160 4e-39 >RSc1647 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 453 Score = 417 bits (1073), Expect = e-116, Method: Compositional matrix adjust. Identities = 207/428 (48%), Positives = 290/428 (67%), Gaps = 2/428 (0%) Query: 14 LFWRTFFLLTFLITASMVAWVASFRMVERGPRAEQLAAQIVSVVTITRAALTHSAPEMRR 73 LFWRTF L+ LI S+ AW SFR+ ER PRA+Q+A QIVSVV +TRAAL +S P RR Sbjct: 20 LFWRTFMLIALLIAISLGAWFQSFRIFEREPRAQQIAMQIVSVVKLTRAALLYSDPARRR 79 Query: 74 ELLFDLASNEGIRIYPLEKSDRIVPPEDSPIVPEL-EYYVRQSLDENTIFASSVNEVEGF 132 LL DL NEGI++YP EK D P+ +P + +L + +R L ++T+ A++VN++ G Sbjct: 80 FLLLDLVQNEGIKVYPREKEDEYRTPQANPYLTQLVQREIRNRLGQDTVIATAVNDIPGV 139 Query: 133 WISFNIDDDQYWLMLDRGRLDRTSGLQWLGWGSIALFLSLIGAVFISTLINQPLARLTAA 192 W+SF I+ D YW+ + R + GLQWL W AL LS++GA FI++ +NQPL RL Sbjct: 140 WVSFQIEGDDYWVAISPDRFEHVPGLQWLWWSIAALVLSVLGAAFITSRVNQPLKRLADT 199 Query: 193 ARAIAKGRQPEPLPESGPTEIEEANRSFNQMVADLNRIESDRALILAGISHDLRTPLARM 252 ARAI+ G P+ LPE G TE+ +AN SFNQMV DL ++E+DRA++LAGISHDLRTPL R+ Sbjct: 200 ARAISAGDDPKSLPEGGGTEVAQANHSFNQMVRDLKQLEADRAVMLAGISHDLRTPLTRL 259 Query: 253 QLEVEMANLSDESRDGMHSDLAQMDSIIGQFLDYAKPFDANSLESIDLAGVLGDVAAKSA 312 +LE EM+ + D++R+ M +D+ QMD+IIGQFLDYA+P LE++DL ++ D A + Sbjct: 260 RLETEMSPVDDQTRELMVADIEQMDAIIGQFLDYARP-SGEMLEAVDLTELVRDTAPVYS 318 Query: 313 RLSDVKLITEITPATEVAGNGTELARVFSNLIENARRYGKTPGTDCAEIHLRSRIEGHQV 372 D+ L ++ P N E R+ NLIENARRYGKT T AEI + + ++G++V Sbjct: 319 AHDDIDLTLKLAPEAIARCNRMETQRILDNLIENARRYGKTHDTGRAEITVSTALQGNEV 378 Query: 373 VVEVFDHGSGVPESECERLLRPFTRLDTARGQANGSGLGLAIVNRIVLKHNGKLLLKGHE 432 V+ V D G+GVP + L RPF RL++AR +A G+GLG++IV+RI+ + G+L L+ Sbjct: 379 VLCVADRGAGVPADQLALLTRPFYRLESARSEAKGAGLGMSIVSRILQRSGGRLTLENRT 438 Query: 433 ETHGGLLI 440 GL++ Sbjct: 439 PPETGLVV 446 >VC2713 [T] COG0642 Signal transduction histidine kinase Vch Vibrio cholerae Length = 438 Score = 180 bits (456), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 112/289 (38%), Positives = 165/289 (57%), Gaps = 15/289 (5%) Query: 166 IALFLSLIGAVFISTLINQPLARLTAAARAIAKGRQPEPLPESGPTEIEEANRSFNQMVA 225 +AL + + G +FI L N+PL L AA+ + +G P LPE G EI R+FN+M Sbjct: 160 MALLIVIGGWLFIR-LQNRPLIALEKAAKMVGRGETPPHLPEQGTLEIRSVTRAFNRMSK 218 Query: 226 DLNRIESDRALILAGISHDLRTPLARMQLEVEMANLSDES-RDGMHSDLAQMDSIIGQFL 284 + +E DRAL++AGISHD+RTPL R++L EM + D + + SD + + II QF+ Sbjct: 219 GIQALEEDRALLMAGISHDIRTPLTRIRLATEMMSPEDSYLAESIISDTEECNQIISQFM 278 Query: 285 DYAKPFDANSLESIDLAGVLGDVAAKSARLSDVKLITEITPATEVA-GNGTELARVFSNL 343 DY KP + + E++DL + DVA+ +V++ TE+ A GN + R SNL Sbjct: 279 DYLKPVNREAFEAVDLNDIASDVASSEGGY-EVQIETELQAGLAPALGNPIAIKRSLSNL 337 Query: 344 IENARRYGKTPGTDCAEIHLRSRIEGHQVVV--EVFDHGSGVPESECERLLRPFTRLDTA 401 + NA RYG + + S + + +V V D+G G+ S+ ++ PFTR DTA Sbjct: 338 VVNALRYGN------GWVKVSSGMTADKKLVWLSVEDNGPGIDPSQVNKVFEPFTRGDTA 391 Query: 402 RGQANGSGLGLAIVNRIVLKHNGKLLLKGHEETHGGLLIQISLPLKGHR 450 RG + G+GLGLAIV RIV +H+G + + + GGL QIS P K + Sbjct: 392 RG-SEGTGLGLAIVKRIVSQHHGAVSVSNR--SQGGLRAQISFPTKQQK 437 >envZ [T] COG0642 Signal transduction histidine kinase Eco Escherichia coli K12 Length = 450 Score = 160 bits (406), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 107/286 (37%), Positives = 161/286 (56%), Gaps = 15/286 (5%) Query: 165 SIALFLSLIGAVFISTLI-NQPLARLTAAARAIAKGRQPEPLPESGPTEIEEANRSFNQM 223 ++A+ L IG ++ I N+PL L AA + KG P PL E G +E+ R+FN M Sbjct: 164 TLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHM 223 Query: 224 VADLNRIESDRALILAGISHDLRTPLARMQLEVEMANLSDES-RDGMHSDLAQMDSIIGQ 282 A + ++ DR L++AG+SHDLRTPL R++L EM + D + ++ D+ + ++II Q Sbjct: 224 AAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEECNAIIEQ 283 Query: 283 FLDYAKPFDANSLESIDLAGVLGDV-AAKSARLSDVKLITEITPAT-EVAGNGTELARVF 340 F+DY + +E DL VLG+V AA+S +++ T + P + EV + + R Sbjct: 284 FIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIE--TALYPGSIEVKMHPLSIKRAV 341 Query: 341 SNLIENARRYGKTPGTDCAEIHLRSRIEGHQVVVEVFDHGSGVPESECERLLRPFTRLDT 400 +N++ NA RYG I + S E ++ +V D G G+ + + L +PF R D+ Sbjct: 342 ANMVVNAARYGN------GWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDS 395 Query: 401 ARGQANGSGLGLAIVNRIVLKHNGKLLLKGHEETHGGLLIQISLPL 446 AR +G+GLGLAIV RIV HNG L L E GGL I+ LP+ Sbjct: 396 AR-TISGTGLGLAIVQRIVDNHNGMLELGTSE--RGGLSIRAWLPV 438 >ZenvZ [T] COG0642 Signal transduction histidine kinase EcZ Escherichia coli O157:H7 EDL933 Length = 450 Score = 160 bits (406), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 107/286 (37%), Positives = 161/286 (56%), Gaps = 15/286 (5%) Query: 165 SIALFLSLIGAVFISTLI-NQPLARLTAAARAIAKGRQPEPLPESGPTEIEEANRSFNQM 223 ++A+ L IG ++ I N+PL L AA + KG P PL E G +E+ R+FN M Sbjct: 164 TLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHM 223 Query: 224 VADLNRIESDRALILAGISHDLRTPLARMQLEVEMANLSDES-RDGMHSDLAQMDSIIGQ 282 A + ++ DR L++AG+SHDLRTPL R++L EM + D + ++ D+ + ++II Q Sbjct: 224 AAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEECNAIIEQ 283 Query: 283 FLDYAKPFDANSLESIDLAGVLGDV-AAKSARLSDVKLITEITPAT-EVAGNGTELARVF 340 F+DY + +E DL VLG+V AA+S +++ T + P + EV + + R Sbjct: 284 FIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIE--TALYPGSIEVKMHPLSIKRAV 341 Query: 341 SNLIENARRYGKTPGTDCAEIHLRSRIEGHQVVVEVFDHGSGVPESECERLLRPFTRLDT 400 +N++ NA RYG I + S E ++ +V D G G+ + + L +PF R D+ Sbjct: 342 ANMVVNAARYGN------GWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDS 395 Query: 401 ARGQANGSGLGLAIVNRIVLKHNGKLLLKGHEETHGGLLIQISLPL 446 AR +G+GLGLAIV RIV HNG L L E GGL I+ LP+ Sbjct: 396 AR-TISGTGLGLAIVQRIVDNHNGMLELGTSE--RGGLSIRAWLPV 438 >ECs4246 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 450 Score = 160 bits (406), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 107/286 (37%), Positives = 161/286 (56%), Gaps = 15/286 (5%) Query: 165 SIALFLSLIGAVFISTLI-NQPLARLTAAARAIAKGRQPEPLPESGPTEIEEANRSFNQM 223 ++A+ L IG ++ I N+PL L AA + KG P PL E G +E+ R+FN M Sbjct: 164 TLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHM 223 Query: 224 VADLNRIESDRALILAGISHDLRTPLARMQLEVEMANLSDES-RDGMHSDLAQMDSIIGQ 282 A + ++ DR L++AG+SHDLRTPL R++L EM + D + ++ D+ + ++II Q Sbjct: 224 AAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEECNAIIEQ 283 Query: 283 FLDYAKPFDANSLESIDLAGVLGDV-AAKSARLSDVKLITEITPAT-EVAGNGTELARVF 340 F+DY + +E DL VLG+V AA+S +++ T + P + EV + + R Sbjct: 284 FIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIE--TALYPGSIEVKMHPLSIKRAV 341 Query: 341 SNLIENARRYGKTPGTDCAEIHLRSRIEGHQVVVEVFDHGSGVPESECERLLRPFTRLDT 400 +N++ NA RYG I + S E ++ +V D G G+ + + L +PF R D+ Sbjct: 342 ANMVVNAARYGN------GWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDS 395 Query: 401 ARGQANGSGLGLAIVNRIVLKHNGKLLLKGHEETHGGLLIQISLPL 446 AR +G+GLGLAIV RIV HNG L L E GGL I+ LP+ Sbjct: 396 AR-TISGTGLGLAIVQRIVDNHNGMLELGTSE--RGGLSIRAWLPV 438