BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0222.p (385 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl2702 [F] COG0027 Formate-dependent phosphoribosylglycinamide ... 480 e-135 PA3751 [F] COG0027 Formate-dependent phosphoribosylglycinamide f... 469 e-132 PM1053 Non COG 453 e-127 MJ1486 [F] COG0027 Formate-dependent phosphoribosylglycinamide f... 453 e-127 VC1228 [F] COG0027 Formate-dependent phosphoribosylglycinamide f... 442 e-124 >Cgl2702 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Cgl Corynebacterium glutamicum Length = 408 Score = 480 bits (1235), Expect = e-135, Method: Compositional matrix adjust. Identities = 234/381 (61%), Positives = 295/381 (77%), Gaps = 1/381 (0%) Query: 1 MLLGSGELGKEVIIALQRLGVEVIAVDRYENAPGQQVAHRAHVINMTDGAALAALIEQEQ 60 MLLGSGELGKEV IA QRLG+EV AVDRYE+AP QVAH ++VI+MTD A + L+E+ + Sbjct: 19 MLLGSGELGKEVAIAFQRLGLEVHAVDRYEHAPAHQVAHFSYVIDMTDAAQVRELVERVR 78 Query: 61 PDLIVPEIEAIATETLVKLEEAGRARVIPTARAAWLTMNREGIRRLAGETLGLATSPYRF 120 PD ++PEIEA+AT+ LVK+EE G A ++PTARAA LTMNREGIR+LA E LGL TS Y F Sbjct: 79 PDFVIPEIEALATDELVKIEEEGLATIVPTARAAKLTMNREGIRKLAAEELGLPTSNYEF 138 Query: 121 ADSLDELKAAIDQIGFPCVIKPVMSSSGKGQSKIDGPDEIEAAWNYAAAGGRVDSGRVIV 180 + +E AA +++G+P V+KPVMSSSGKGQS + D+++AAW+YA +G RV + RVIV Sbjct: 139 CSTFEEFSAAAEKLGYPNVVKPVMSSSGKGQSVLRSSDDLQAAWDYAMSGARVANSRVIV 198 Query: 181 EGFIDFDYEITLLTVRSLN-ENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEKAR 239 E F++FDYEITLLTVRS++ T FC+PIGH Q GDYVESWQP M ALE AR Sbjct: 199 EAFVEFDYEITLLTVRSIDPTTSKPATWFCEPIGHRQEDGDYVESWQPMEMTPRALENAR 258 Query: 240 DIARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFELHAKAIL 299 +A ++T LGG G+FGVELFV GD V+FSEVSPRPHDTG+VT+ +Q SEFELHAKAIL Sbjct: 259 SVAARITNALGGRGVFGVELFVSGDDVYFSEVSPRPHDTGLVTLATQRFSEFELHAKAIL 318 Query: 300 GLPVNTALRSPGASAVIYGQHDARGIAFDGVAEALRIPGADIRLFGKPESFARRRMGVAL 359 GLPV+ L SPGASAVIYG ++ G+++ G+AEAL + D+R+F KPE+F +RRMGVA+ Sbjct: 319 GLPVDVTLISPGASAVIYGGIESEGVSYTGLAEALAVAETDLRIFAKPEAFTKRRMGVAV 378 Query: 360 ASGDSVETARIRAKQAAAKVK 380 ++ + V AR RA AAA +K Sbjct: 379 STAEDVAAARDRATLAAAAIK 399 >PA3751 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Pae Pseudomonas aeruginosa Length = 393 Score = 469 bits (1208), Expect = e-132, Method: Compositional matrix adjust. Identities = 238/367 (64%), Positives = 282/367 (76%), Gaps = 7/367 (1%) Query: 1 MLLGSGELGKEVIIALQRLGVEVIAVDRYENAPGQQVAHRAHVINMTDGAALAALIEQEQ 60 +L GSGELGKEV I LQRLG EVIAVDRY NAP QVAHR+HVI+M DGAAL A+IEQE+ Sbjct: 16 LLCGSGELGKEVAIELQRLGCEVIAVDRYGNAPAMQVAHRSHVISMLDGAALRAVIEQEK 75 Query: 61 PDLIVPEIEAIATETLVKLEEAGRARVIPTARAAWLTMNREGIRRLAGETLGLATSPYRF 120 P IVPEIEAIAT TLV+LE G V+PTARAA LTMNREGIRRLA E LGL TSPY F Sbjct: 76 PHYIVPEIEAIATATLVELEAEGYT-VVPTARAAQLTMNREGIRRLAAEELGLPTSPYHF 134 Query: 121 ADSLDELKAAIDQIGFPCVIKPVMSSSGKGQSKIDGPDEIEAAWNYAAAGGRVDSGRVIV 180 AD+ ++ + ++++G+PCV+KP+MSSSGKGQS + GPD+++AAW+YA GGR GRVIV Sbjct: 135 ADTFEDYRRGVERVGYPCVVKPIMSSSGKGQSVLKGPDDLQAAWDYAQEGGRAGKGRVIV 194 Query: 181 EGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEKARD 240 EGFIDFDYEITLLTVR ++ T+FC PIGH QVKGDY ESWQP M AL ++ Sbjct: 195 EGFIDFDYEITLLTVRHVDG-----TTFCAPIGHRQVKGDYHESWQPQAMSAQALAESER 249 Query: 241 IARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFELHAKAILG 300 +AR VTE LGG GLFGVELFVKGD VWFSEVSPRPHDTG+VT++SQ SEF LHA+AILG Sbjct: 250 VARAVTEALGGRGLFGVELFVKGDQVWFSEVSPRPHDTGLVTLISQDLSEFALHARAILG 309 Query: 301 LPVNTALR-SPGASAVIYGQHDARGIAFDGVAEALRIPGADIRLFGKPESFARRRMGVAL 359 LP+ + P ASAVI + +R +AF + AL +RLFGKPE +RRMGVAL Sbjct: 310 LPIPVIRQLGPSASAVILVEGKSRQVAFANLGAALSEADTALRLFGKPEVDGQRRMGVAL 369 Query: 360 ASGDSVE 366 A +S++ Sbjct: 370 ARDESID 376 >PM1053 Non COG Length = 393 Score = 453 bits (1166), Expect = e-127, Method: Compositional matrix adjust. Identities = 234/381 (61%), Positives = 284/381 (74%), Gaps = 7/381 (1%) Query: 1 MLLGSGELGKEVIIALQRLGVEVIAVDRYENAPGQQVAHRAHVINMTDGAALAALIEQEQ 60 M+LGSGELGKEV+I LQRLGVEVIAVDRY NAP QQVAHRA+ I+M DG AL AL+E+E+ Sbjct: 16 MMLGSGELGKEVVIELQRLGVEVIAVDRYANAPAQQVAHRAYTISMLDGEALKALVEKEK 75 Query: 61 PDLIVPEIEAIATETLVKLEEAGRARVIPTARAAWLTMNREGIRRLAGETLGLATSPYRF 120 PD IVPE+EAIAT TLV+LE+AG VIPTA+A LTMNREGIRRLA E LGL TS Y+F Sbjct: 76 PDYIVPEVEAIATATLVELEQAGFT-VIPTAKATQLTMNREGIRRLAAEELGLPTSNYQF 134 Query: 121 ADSLDELKAAIDQIGFPCVIKPVMSSSGKGQSKIDGPDEIEAAWNYAAAGGRVDSGRVIV 180 D+ D+ K A+++IG PCV+KP+MSSSG GQS + ++I +AW YA GGR +GRVIV Sbjct: 135 VDNFDDFKRAVEKIGIPCVVKPIMSSSGHGQSILKSVEQIPSAWEYAQQGGRAGAGRVIV 194 Query: 181 EGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEKARD 240 EGF+ FDYEITLLTVR ++ TSF PIGH+Q+ GDY ESWQP M ALEKA+ Sbjct: 195 EGFVKFDYEITLLTVRHVHG-----TSFLAPIGHIQIDGDYRESWQPQAMSAVALEKAQA 249 Query: 241 IARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFELHAKAILG 300 IA K+T LGG G+FGVE+FV GD V F+EVSPRPHDTGMVT++SQ SEF LHA+AILG Sbjct: 250 IAEKITGALGGRGIFGVEMFVCGDEVIFNEVSPRPHDTGMVTLISQELSEFALHARAILG 309 Query: 301 LPV-NTALRSPGASAVIYGQHDARGIAFDGVAEALRIPGADIRLFGKPESFARRRMGVAL 359 LP+ + L SP AS I + + + F +AE L P ++RLFGK E RRMGV L Sbjct: 310 LPIPDITLISPSASKAIVVEGKSTQVVFGQLAEVLAEPHTNLRLFGKGEVDGHRRMGVIL 369 Query: 360 ASGDSVETARIRAKQAAAKVK 380 A SVE A +A++A K++ Sbjct: 370 ARDISVEKALEKARRAYDKLE 390 >MJ1486 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Mja Methanococcus jannaschii Length = 393 Score = 453 bits (1165), Expect = e-127, Method: Compositional matrix adjust. Identities = 228/380 (60%), Positives = 281/380 (73%), Gaps = 7/380 (1%) Query: 1 MLLGSGELGKEVIIALQRLGVEVIAVDRYENAPGQQVAHRAHVINMTDGAALAALIEQEQ 60 +LLGSGELGKEV+I QRLG+E IAVDRY+NAP QVAH+++VI+M D AL A+IE+E+ Sbjct: 19 LLLGSGELGKEVVIEAQRLGIECIAVDRYQNAPAMQVAHKSYVIDMKDYDALMAIIEREE 78 Query: 61 PDLIVPEIEAIATETLVKLEEAGRARVIPTARAAWLTMNREGIRRLAGETLGLATSPYRF 120 PD IVPEIEAI T+ L+ E+ G VIPTA A +TMNRE IRRLA E LGL T+ Y F Sbjct: 79 PDYIVPEIEAINTDALIDAEKMGYT-VIPTAEATKITMNRELIRRLAAEKLGLKTAKYEF 137 Query: 121 ADSLDELKAAIDQIGFPCVIKPVMSSSGKGQSKIDGPDEIEAAWNYAAAGGRVDSGRVIV 180 ADSL+EL+ A++++G PCV+KP+MSSSGKGQS + ++IE AW A G R RVIV Sbjct: 138 ADSLEELRDAVEKLGLPCVVKPIMSSSGKGQSVVRSEEDIEKAWKIAKEGARGIGNRVIV 197 Query: 181 EGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEKARD 240 E FI+FDYEITLLT R+ T FC+PIGHVQ+ GDY ESWQPH M E+A+D Sbjct: 198 EEFINFDYEITLLTARTAEG-----TKFCEPIGHVQIDGDYHESWQPHNMSAELKEQAQD 252 Query: 241 IARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFELHAKAILG 300 IA+KVT+ LGG G+FGVELFVKGD V FSEVSPRPHDTGMVTM++Q SEFE+H +AILG Sbjct: 253 IAKKVTDALGGYGIFGVELFVKGDEVIFSEVSPRPHDTGMVTMITQEMSEFEIHVRAILG 312 Query: 301 LPVNTALRSPGASAVIYGQHDARGIAFDGVAEALRIPGADIRLFGKPESFARRRMGVALA 360 LPV+T L PGAS VI + + + + +AL++P +RLFGKP + RRMGVALA Sbjct: 313 LPVSTKLIHPGASHVIKAEINKYAPKYH-IEDALKVPNTKLRLFGKPNAKVGRRMGVALA 371 Query: 361 SGDSVETARIRAKQAAAKVK 380 DSVE AR A++ A V+ Sbjct: 372 YADSVEKARELAEKCAHAVR 391 >VC1228 [F] COG0027 Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Vch Vibrio cholerae Length = 393 Score = 442 bits (1138), Expect = e-124, Method: Compositional matrix adjust. Identities = 227/381 (59%), Positives = 272/381 (71%), Gaps = 7/381 (1%) Query: 1 MLLGSGELGKEVIIALQRLGVEVIAVDRYENAPGQQVAHRAHVINMTDGAALAALIEQEQ 60 +LLGSGELGKEV I QRLG+EVIA DRY +AP QVAHR+HV +M D AL +I+ E+ Sbjct: 16 LLLGSGELGKEVAIECQRLGLEVIACDRYADAPAMQVAHRSHVFDMLDADALQQVIDLEK 75 Query: 61 PDLIVPEIEAIATETLVKLEEAGRARVIPTARAAWLTMNREGIRRLAGETLGLATSPYRF 120 P +VPEIEAIAT LV+LE G V+PTA A LTMNREGIRRLA E LGL TS Y+F Sbjct: 76 PHFVVPEIEAIATSKLVELEAQG-LNVVPTANATRLTMNREGIRRLAAEELGLPTSAYQF 134 Query: 121 ADSLDELKAAIDQIGFPCVIKPVMSSSGKGQSKIDGPDEIEAAWNYAAAGGRVDSGRVIV 180 ADS + AA++ IG PCV KPVMSSSGKGQS I P++IEAAW YA GGR +GRVIV Sbjct: 135 ADSYESFAAAVETIGLPCVCKPVMSSSGKGQSVIRTPEQIEAAWQYAQQGGRSGAGRVIV 194 Query: 181 EGFIDFDYEITLLTVRSLNENGDTITSFCDPIGHVQVKGDYVESWQPHPMPGAALEKARD 240 EGF+DFDYEITLLTVR+++ FC PIGH Q GDY ESWQP M A++ A Sbjct: 195 EGFVDFDYEITLLTVRAVDG-----VHFCAPIGHRQEDGDYRESWQPQVMSENAIKAAEY 249 Query: 241 IARKVTENLGGLGLFGVELFVKGDMVWFSEVSPRPHDTGMVTMVSQVQSEFELHAKAILG 300 +A +V LGG GLFGVELFVKGD V F+EVSPRPHDTGMVT++SQ SEF LH +A G Sbjct: 250 VAEQVVNALGGYGLFGVELFVKGDKVIFNEVSPRPHDTGMVTLISQELSEFALHVRAFTG 309 Query: 301 LPVNTALR-SPGASAVIYGQHDARGIAFDGVAEALRIPGADIRLFGKPESFARRRMGVAL 359 LP+ ++ P ASA I GQ ++ I F+G+ +AL IP +RLFGKP+ RRR+GVAL Sbjct: 310 LPIGQIVQYGPSASAAILGQGQSQNIQFNGLDDALSIPHTQVRLFGKPDIAGRRRLGVAL 369 Query: 360 ASGDSVETARIRAKQAAAKVK 380 + G + + A RA + A VK Sbjct: 370 SRGKTTQEATDRAIECAKAVK 390