BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0215.p (341 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0547 [GEPR] COG0477 Permeases of the major facilitator superf... 432 e-121 CC0980 [GEPR] COG0477 Permeases of the major facilitator superfa... 422 e-118 PA3709 [GEPR] COG0477 Permeases of the major facilitator superfa... 385 e-107 SMc04407 [GEPR] COG0477 Permeases of the major facilitator super... 370 e-102 AGc4527 [GEPR] COG0477 Permeases of the major facilitator superf... 364 e-100 >RSc0547 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 567 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 226/347 (65%), Positives = 272/347 (78%), Gaps = 6/347 (1%) Query: 1 MSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGLTAGQAVVWYTGQFYALF 60 +SM+ESPAF KMKAEGKTSKAPLTE+FGQW+NLK+VILALVGLTAGQAVVWYTGQFYALF Sbjct: 219 LSMSESPAFQKMKAEGKTSKAPLTESFGQWRNLKIVILALVGLTAGQAVVWYTGQFYALF 278 Query: 61 FLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGRKPIILGGCLIAAVTYFPIFN 120 FLTQ LKVD TAN+LIA AL + TPFF+FFGSLSD+IGRK II+ GCL+A +TYFP+F Sbjct: 279 FLTQVLKVDAFTANVLIAVALAIGTPFFVFFGSLSDRIGRKGIIMAGCLLAVLTYFPLFK 338 Query: 121 GLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTK-KFTSSCDIVKAKLSAASVNYQ 179 LTH+ANPALE A Q + + + ADP C FQ +P + F SSCDI K L+ +S +Y+ Sbjct: 339 ALTHYANPALERAQQTAQITIKADPKECSFQGSPIAREVDFRSSCDIAKRTLAQSSASYE 398 Query: 180 NVAGAPGSVATVKIGDRVITSYDAAGLSKE---DAAAKDK--ELSKALADDIKAAGYPSK 234 + G++A+V I R I S +A+ + DA +K K + K+++D +KAA YPSK Sbjct: 399 SEDAPAGTIASVTIAGREIASLNASRTADGQNFDADSKKKITDFKKSVSDALKAANYPSK 458 Query: 235 ADPEQINKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMPYHIGNGWFGGL 294 ADP Q+N MVL++L ILVIYVTMVYGPIAA LVE+FPTRIRYTSMS+PYHIGNGWFGGL Sbjct: 459 ADPAQMNTVMVLVILVILVIYVTMVYGPIAAMLVELFPTRIRYTSMSLPYHIGNGWFGGL 518 Query: 295 LPTTSFALVAFKGDIYYGLWYPIVISLITVVIGLLFVKETVRNNIHE 341 LPT SFALVA G+IYYGLWYPI I+ IT VIG LFV+ET +I+ Sbjct: 519 LPTISFALVAQHGNIYYGLWYPIWIAAITFVIGALFVRETKDVDIYR 565 >CC0980 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 567 Score = 422 bits (1086), Expect = e-118, Method: Compositional matrix adjust. Identities = 206/341 (60%), Positives = 254/341 (74%) Query: 1 MSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGLTAGQAVVWYTGQFYALF 60 + ++ESP F +M AEGK SK PLTEAFG W NLK+V+LALVGLT GQAVVWYTGQFYALF Sbjct: 227 LKLHESPTFERMIAEGKGSKKPLTEAFGNWPNLKIVLLALVGLTMGQAVVWYTGQFYALF 286 Query: 61 FLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGRKPIILGGCLIAAVTYFPIFN 120 FL +TLK+DG AN L+A ALL+ TPFF+ G LSDKIGRKPII+ GCL+AA+TYFPIF Sbjct: 287 FLEKTLKLDGALANTLVAVALLIGTPFFVICGWLSDKIGRKPIIILGCLLAALTYFPIFK 346 Query: 121 GLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTSSCDIVKAKLSAASVNYQN 180 +T +ANPAL A +PV+VTAD A+C FQF+ G KF + CD+ KA L+ A V+Y Sbjct: 347 AITTYANPALAKAEATAPVVVTADTATCAFQFDLIGKAKFNTPCDVAKAYLAKAGVSYSV 406 Query: 181 VAGAPGSVATVKIGDRVITSYDAAGLSKEDAAAKDKELSKALADDIKAAGYPSKADPEQI 240 A G+ VK+GD + D+ G + + A K L +KAAGYP+KAD + Sbjct: 407 QAAPAGTPTAVKVGDVTLEGLDSKGATGQAFADARKAWEADLGAQLKAAGYPAKADAALV 466 Query: 241 NKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSF 300 NKP V+ LL +LVIYVTMVYGPIAA LVE+FPTRIRYT+MS+PYHIGNGWFGG LPTT+F Sbjct: 467 NKPAVIGLLALLVIYVTMVYGPIAAMLVELFPTRIRYTAMSLPYHIGNGWFGGFLPTTAF 526 Query: 301 ALVAFKGDIYYGLWYPIVISLITVVIGLLFVKETVRNNIHE 341 A+VA GDIY GLWYP++I+ IT V+G LF+K+T N + + Sbjct: 527 AIVAATGDIYSGLWYPVIIAAITAVVGGLFLKDTRHNRLED 567 >PA3709 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 539 Score = 385 bits (989), Expect = e-107, Method: Compositional matrix adjust. Identities = 191/341 (56%), Positives = 244/341 (71%), Gaps = 16/341 (4%) Query: 1 MSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGLTAGQAVVWYTGQFYALF 60 +SM ESPAFLKMKAEGK SKAPL E+F QW NLK+V+ AL + AGQAV +YT QFY LF Sbjct: 215 LSMRESPAFLKMKAEGKVSKAPLRESFTQWGNLKVVLTALFSINAGQAVTFYTAQFYVLF 274 Query: 61 FLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGRKPIILGGCLIAAVTYFPIFN 120 FLTQ LKVDG TAN L+ AL+L PFF+ G LSD+IGRKP++L G L+A + YFP+F Sbjct: 275 FLTQVLKVDGGTANGLLIVALVLGAPFFIVAGWLSDRIGRKPVLLAGLLLATLFYFPLFK 334 Query: 121 GLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTSSCDIVKAKLSAASVNYQN 180 GLTH+ANPA++ A ++SP+ V ADPA+C FQF+P G F S CD VK L A + Y Sbjct: 335 GLTHYANPAIDQASRQSPISVVADPATCTFQFDPVGKATFDSPCDKVKTFLVKAGLPYST 394 Query: 181 VAGAPGSVATVKIGDRVITSYDAAGLSKEDAAAKDKELSKALADDIKAAGYPSKADPEQI 240 VA GS V+IG+ I +DA +A+A +K AGYP +AD Q+ Sbjct: 395 VAAPAGSDVRVRIGETEIAGFDA----------------EAMAAAVKTAGYPQQADGSQV 438 Query: 241 NKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSF 300 NKPMV+ ++F LV+ T+ YGP+AA +VE+FPTRIRY+S+S+PYHIGNGWFGG LPT SF Sbjct: 439 NKPMVIAIIFALVLISTLCYGPLAALMVELFPTRIRYSSLSLPYHIGNGWFGGFLPTVSF 498 Query: 301 ALVAFKGDIYYGLWYPIVISLITVVIGLLFVKETVRNNIHE 341 ALV + GDI+YGLWYP++I+ ++V LLF++ET +IH Sbjct: 499 ALVVYTGDIFYGLWYPVLITGGSLVCALLFLRETRHTDIHR 539 >SMc04407 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 629 Score = 370 bits (951), Expect = e-102, Method: Compositional matrix adjust. Identities = 204/412 (49%), Positives = 250/412 (60%), Gaps = 72/412 (17%) Query: 1 MSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGLTAGQAVVWYTGQFYALF 60 + MNESPAF KMK EGK SKAPLTEAFGQW+N K+ +LAL G GQAVVWY+GQFYALF Sbjct: 215 LKMNESPAFKKMKEEGKGSKAPLTEAFGQWRNAKIAVLALFGAVVGQAVVWYSGQFYALF 274 Query: 61 FLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGRKPIILGGCLIAAVTYFPIFN 120 FL LKVDG +AN+++AA+LLL T FF+FFG LSDKIGRKPII+ G L+A +TYFP+F Sbjct: 275 FLQSILKVDGQSANLMVAASLLLGTGFFVFFGWLSDKIGRKPIIMAGLLLAMLTYFPLFK 334 Query: 121 GLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTSSC--------------DI 166 LT NPAL A Q VTA P C+FQFNPTGT KFT+SC D+ Sbjct: 335 ALTWAGNPALAEAQQSVRATVTAAPGDCKFQFNPTGTAKFTTSCDIATAFLTKNSVPYDV 394 Query: 167 V----------------------------KAKLSAASVNYQ-----NVAGAPGSVATVKI 193 V +AK A+ Q +G P K+ Sbjct: 395 VTTAAAGTPATVKIGETTITSYDAIAAGDRAKAEEAAFGKQINMALQASGYPLVRGAAKV 454 Query: 194 GDRVITSYDAA----GLSKEDAAAKDKEL---SKALADDI------------------KA 228 + + ++ AA GL A +K + K +AD + K Sbjct: 455 PESKLDAFVAANPELGLDAAAVRAGEKTMVPADKLVADKLLTQEEVGSATEMAVYNIDKG 514 Query: 229 AGYPSKADPEQINKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMPYHIGN 288 + ADP ++N +++ +L +LVIYVTMVYGPIAA LVE+FPTRIRYT MS+PYHIGN Sbjct: 515 GAFTMVADPARVNWTVIIAVLTVLVIYVTMVYGPIAALLVELFPTRIRYTGMSLPYHIGN 574 Query: 289 GWFGGLLPTTSFALVAFKGDIYYGLWYPIVISLITVVIGLLFVKETVRNNIH 340 GWFGGLLP T+FA+ A KGDIYYGLWYPIV + IT+VIGLLF+ ET +IH Sbjct: 575 GWFGGLLPATAFAMSAAKGDIYYGLWYPIVFAGITLVIGLLFLPETKDRDIH 626 >AGc4527 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 657 Score = 364 bits (934), Expect = e-100, Method: Compositional matrix adjust. Identities = 207/411 (50%), Positives = 256/411 (62%), Gaps = 71/411 (17%) Query: 1 MSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGLTAGQAVVWYTGQFYALF 60 + MNESPAF KMK EGKTSKAPL+EAFGQWKN K+ +LALVG GQAVVWYTGQFYALF Sbjct: 244 LKMNESPAFKKMKEEGKTSKAPLSEAFGQWKNAKIALLALVGAVIGQAVVWYTGQFYALF 303 Query: 61 FLTQTLKVDGPTANILIAAALLLATPFFLFFGSLSDKIGRKPIILGGCLIAAVTYFPIFN 120 FL LKVDG +ANI++AAAL+L T FF+ FG LSDKIGRKPII+ G ++A +TYFP+F Sbjct: 304 FLQSILKVDGQSANIMVAAALILGTGFFVLFGWLSDKIGRKPIIMAGLILAMLTYFPLFK 363 Query: 121 GLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTSSC--------------DI 166 LT NPAL A VTA P C+FQFNPTGT KFT+SC D+ Sbjct: 364 ALTWAGNPALAQAQSTVRATVTAAPGDCKFQFNPTGTAKFTTSCDIATSFLTRNSVPYDV 423 Query: 167 V--------KAKLSAASV-NYQ-------------------NVA----GAPGSVATVKIG 194 V KL A++ +Y N+A G P ++ Sbjct: 424 VAGAAGEPASVKLGDATIASYDAIAAGADASAKDKAFQKQINIALHDSGYPLVRGAAQVP 483 Query: 195 DRVITSYDAAG----LSKEDAAAKDKEL---SKALADDI----KAAG------------- 230 D + ++ AA L+ + A DK++ K +AD + + AG Sbjct: 484 DAKLDAFIAANPELNLNADAVRATDKKMVATDKLVADKLLTPAETAGAAEMAVYTIAGGG 543 Query: 231 -YPSKADPEQINKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMPYHIGNG 289 + ADP +N +++ +L +LVIYVTMVYGPIAA LVE+FPTRIRY+ MS+PYHIGNG Sbjct: 544 AFTMVADPAAVNWIVIIAVLTVLVIYVTMVYGPIAALLVELFPTRIRYSGMSLPYHIGNG 603 Query: 290 WFGGLLPTTSFALVAFKGDIYYGLWYPIVISLITVVIGLLFVKETVRNNIH 340 WFGGLLP T+FA+ A KGDIYYGLWYPIV + IT+VIGLLF+ ET +IH Sbjct: 604 WFGGLLPATAFAMSAAKGDIYYGLWYPIVFAGITLVIGLLFLPETKDRDIH 654