BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0203.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0239 [GER] COG0697 Permeases of the drug/metabolite transporte... 179 7e-45 mlr5160 [GER] COG0697 Permeases of the drug/metabolite transport... 136 6e-32 RSp0133 [GER] COG0697 Permeases of the drug/metabolite transport... 132 9e-31 AGl1685 [GER] COG0697 Permeases of the drug/metabolite transport... 120 4e-27 SMc02817 [GER] COG0697 Permeases of the drug/metabolite transpor... 112 1e-24 >PA0239 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 179 bits (454), Expect = 7e-45, Method: Compositional matrix adjust. Identities = 103/283 (36%), Positives = 163/283 (57%), Gaps = 7/283 (2%) Query: 18 GIIFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATLAPLYRRRHGRSI 77 GI+ + + ++ + D K L+ Y +VM+ W RY ++ M A P R+G ++ Sbjct: 17 GILLICAAVFLFASHDGLSKFLS-GFYPIVMVVWARYLVHTLLMVAVFVP----RNGLAV 71 Query: 78 LKSNRLGLQLGRGALLLASTLIFFSVLKIVPLAEGTAMNFCAPMIVLAISPWLLGERSYL 137 ++S R +QL R L+ ++L F + L+ +PLAE TA+NF AP++V A+S LL E+ L Sbjct: 72 IRSRRPLMQLARALCLIGTSLFFTTGLRYLPLAEATAVNFLAPLLVTALSVPLLKEKVSL 131 Query: 138 SRWIAVLIGFTGMLIVIRPSGDIPPVGVALGLVSAFTQALLSILNRKASQADNPMVTLFY 197 +W+AVL GF G+L ++RP G + L SA L +L R + +D+P + F Sbjct: 132 GQWLAVLTGFIGVLFIVRPGGALFTPAALFPLGSALCFGLYQLLTRMLANSDSPTTSNFL 191 Query: 198 GALVGSIVSTLLVPFFWTSHTPTVVELAILVSTGITSTIGHFLQNSAYRHAEASVLTPFF 257 + +++ +LLVPFFW TP+++ ++++ G GH L A+RHA + L PF Sbjct: 192 AGIFNTLIMSLLVPFFW--QTPSLLHGLMMIALGGCGMGGHLLLTQAFRHAPPATLAPFS 249 Query: 258 YAQIISACGMGWLVFGQFPDQITVLGIAIICASGIGIAYIEHK 300 Y QII A +G LVFG PD +LGI +ICASG+ +A+ + Sbjct: 250 YGQIIFAGLLGLLVFGHVPDAWALLGILVICASGLVVAWRRGR 292 >mlr5160 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 313 Score = 136 bits (342), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 89/275 (32%), Positives = 146/275 (53%), Gaps = 11/275 (4%) Query: 29 LSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATLAPLYRRRHGRSILKSNRLGL--Q 86 + LDT+ K L LAG +++AW+R+ +++ + L R R L+ + L Sbjct: 27 FTFLDTSSKYLVLAGVSALIVAWVRFAVHVVLVGTLL------RGWRDPLRFRPVNLPAH 80 Query: 87 LGRGALLLASTLIFFSVLKIVPLAEGTAMNFCAPMIVLAISPWLLGERSYLSRWIAVLIG 146 + RG L ST+ L+ + LAE T++ F PM++ A++ LLGE + RW+A+L Sbjct: 81 VLRGVFLFGSTMCNILALRSLQLAETTSIYFFGPMVITALAGPLLGEWAGWRRWLAILAA 140 Query: 147 FTGMLIVIRPSGDIPPVGVALGLVSAFTQALLSILNRKASQADNPMVTLFYGALVGSIVS 206 F G+LI+ RP + +G L S + I+ R+ S + + + AL +++ Sbjct: 141 FAGVLIITRPGVGVFGIGHLFALGSMLSNCFYVIMTRRMSSTETSESLILFSALAPTVLL 200 Query: 207 TLLVPF-FWTSHTPTVVELAILVSTGITSTIGHFLQNSAYRHAEASVLTPFFYAQIISAC 265 ++PF F H IL+ G+ +GH+L AYR A + L P+ Y+Q++ Sbjct: 201 LPMLPFSFSLPHDGW--HWFILLMLGVFGGVGHWLLVQAYRLATTTALAPYPYSQMVWMV 258 Query: 266 GMGWLVFGQFPDQITVLGIAIICASGIGIAYIEHK 300 GW+VF QFPD+ T++G AII ASG+ I + EH+ Sbjct: 259 ISGWIVFKQFPDRWTLVGAAIIVASGLYIVHREHR 293 >RSp0133 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 132 bits (333), Expect = 9e-31, Method: Compositional matrix adjust. Identities = 108/300 (36%), Positives = 154/300 (51%), Gaps = 11/300 (3%) Query: 7 PYIRIAHNHKL-GIIFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATL 65 P I H L GI FLI+ + ++ DT K +++ VVM W RY + ATL Sbjct: 17 PTILTRSQHPLQGIAFLIAAVAFFAVFDTLTKYISIT-VPVVMALWFRYLFQMVATGATL 75 Query: 66 APLYRRRHGRSILKSNRLGLQLGRGALLLASTLIFFSVLKIVPLAEGTAMNFCAPMIVLA 125 P GRS+L++ R LQ+ RG LLL +L F L+ +P+ + TA+ P++V Sbjct: 76 LP----SRGRSLLRTRRPWLQVVRGLLLLLVSLFSFLSLRRMPVGDVTAIVMLTPLVVTF 131 Query: 126 ISPWLLGERSYLSRWIAVLIGFTGMLIVIRPSGDIPPVGVALGLVSAFTQALLSILNRKA 185 ++ LGE+ +RWI + GF G L+VIRP G G+ L L A ++ + Sbjct: 132 VAAVSLGEQVSATRWIFMAGGFFGALMVIRPGGAAFDWGMLLPLGMVVANAAFQVVTSRL 191 Query: 186 SQADNPMVTLFYGALVGSIVSTLLVPFFWTSHTPTVVELAILVSTGITSTIGHFLQNSAY 245 + D T FY VG+++ T ++PF W + L IL+ GI S+ GH L AY Sbjct: 192 ANVDEAGTTQFYTGAVGALLLTCMLPFGWQALGGKWWWLLILI--GIVSSSGHALLIMAY 249 Query: 246 RHAEASVLTPFFYAQIISACGMGWLVFGQFPDQITVLGIAIIC---ASGIGIAYIEHKRA 302 A ++LTP+ Y QI A GWLVF PD +V GIAII A+G +A E + A Sbjct: 250 TRAPVAMLTPYLYMQIGFAMIGGWLVFSHVPDGWSVAGIAIIAMCGAAGTWVAARERRMA 309 >AGl1685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 120 bits (301), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 89/288 (30%), Positives = 144/288 (50%), Gaps = 13/288 (4%) Query: 16 KLGIIFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRY---TINLFFMAATLAPLYRRR 72 K G ++ + + D K L A Y V +A +RY + + MAA R Sbjct: 5 KTGFLYALVAFTIFAAQDGISKHLGSA-YPPVFVAMLRYWAFAVFVLLMAA------RSA 57 Query: 73 HG-RSILKSNRLGLQLGRGALLLASTLIFFSVLKIVPLAEGTAMNFCAPMIVLAISPWLL 131 G R + +NR LQ+ RG LL + +V LA ++ AP+IV A+S LL Sbjct: 58 GGIRGAVMANRPWLQISRGVLLAVQIVFSIFSFAVVGLAHSHSILASAPLIVAALSMPLL 117 Query: 132 GERSYLSRWIAVLIGFTGMLIVIRPSGDIPPVGVALGLVSAFTQALLSILNRKASQADNP 191 GE RW A+ +GF G+L++++P GD + + V+AF AL S+L R S++D+ Sbjct: 118 GEHVGWRRWCAIFVGFIGVLVILKPDGDGFDNKLIITFVAAFMLALYSVLTRLGSKSDSA 177 Query: 192 MVTLFYGALVGSIVSTLLVPFFWTSHTPTVVELAILVSTGITSTIGHFLQNSAYRHAEAS 251 M + FY + G+ TL+ PF+W P + +++ IT GH+ A+ A+A+ Sbjct: 178 MTSFFYTGVAGAAALTLVGPFYWVPLAPQ--DWGWMLALCITGMSGHYCLIKAFELADAA 235 Query: 252 VLTPFFYAQIISACGMGWLVFGQFPDQITVLGIAIICASGIGIAYIEH 299 + PF Y Q++ +G ++G+ V G AI+ A+G+ + EH Sbjct: 236 SVQPFSYYQLVLVSIIGVTIYGEVVTSNMVTGAAIVIAAGLFTIWREH 283 >SMc02817 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 317 Score = 112 bits (280), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 98/320 (30%), Positives = 150/320 (46%), Gaps = 15/320 (4%) Query: 1 MSSAVLPYIRIAHNH-KLGIIFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLF 59 MS L I HN G+ ++ + L+D KL A+A I R+ + + Sbjct: 1 MSELSLSKAAIDHNRISYGLTLMVLSVLLSPLIDIFSKL-AIATVPSAEITAARFLLQIV 59 Query: 60 FMAATLAPLYRRRHGRSILKSNRLGLQLGRGALLLASTLIFFSVLKIVPLAEGTAMNFCA 119 F + P+ R L + L RG LL+ + L F + LK++ +A+ A+ F Sbjct: 60 F----ILPIVLVRGTLFDLTWRKSALHALRGGLLVVTMLSFITTLKVMEVADAIAIFFVE 115 Query: 120 PMIVLAISPWLLGERSYLSRWIAVLIGFTGMLIVIRPSGDIPPVGVALGLVSAFTQALLS 179 P+I+ + L E R+ A +GF G L+VI+PS + L +V+AF A+ Sbjct: 116 PIILTILGSIFLKETIGWRRYTACAVGFLGSLLVIQPSMQEVGLVALLPIVAAFGLAVFL 175 Query: 180 ILNRKASQADNPMVTLFYGALVGSIVSTLLVPFFWTSHT-------PTVVELAILVSTGI 232 ++ R +Q ++P F+ + G + L+ F S + P L+ G+ Sbjct: 176 LVTRMVAQNEDPWSMQFHAGIWGGLFCLALLWFGEGSGSSVFDPVWPDGRAWYYLLGVGV 235 Query: 233 TSTIGHFLQNSAYRHAEASVLTPFFYAQIISACGMGWLVFGQFPDQITVLGIAIICASGI 292 T+TI L AYR A ASVL P Y +I+SA GWLVFG PD + LGIAII SG+ Sbjct: 236 TATISGVLGVYAYRAAPASVLAPLQYLEIVSATIFGWLVFGDLPDALKWLGIAIIIGSGL 295 Query: 293 GIAYIEH--KRAHPLPPADP 310 I + E ++ + P P Sbjct: 296 YIIWRERQVQKTAGIAPVSP 315