BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0181.p (435 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 598 e-171 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 520 e-147 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 464 e-130 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 398 e-110 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 365 e-100 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 598 bits (1543), Expect = e-171, Method: Compositional matrix adjust. Identities = 302/432 (69%), Positives = 366/432 (84%) Query: 4 QAGAAADGARASFEDATYSKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTV 63 AGA + + FE+ATY KV+WRL+P L LCYV +YLDRVNVGFAKLQML DLKFS+TV Sbjct: 11 SAGALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFSETV 70 Query: 64 YGLGAGIFFLGYFVFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVSTPEMFYIMRF 123 YGLGAGIFF+GYF+FEVPSN+ILH+VGAR+WIARIMI+WG+IS AM +V+TP MFY+MRF Sbjct: 71 YGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYVMRF 130 Query: 124 LLGVAEAGFFPGVILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWG 183 LLG+AEAGFFPG+ILYLTYWYPA RRG+ T FMT +ALSGVIGGP+SGW + GV+G Sbjct: 131 LLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGGVYG 190 Query: 184 HTGWQWMFILEAIPSLILGVLVILYMKDRIRDAEWLTEDEKRLLETNISHEESQKEHLSL 243 GWQWMF++E IPS+++G+ V+ Y+ +RI A WLT++EK LL NI+ EE+QKE + Sbjct: 191 LAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEEAQKEDAPI 250 Query: 244 GAMFANGRVWLGALIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAM 303 A+ A+ RVWL +LIYF FVMGLYGVSFWLPT+IK TGV+DPL+VGLLTAIPY A AM Sbjct: 251 AAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAAVVAM 310 Query: 304 VLIGRSADARRERRWHVAIPAFIGCIGLLLSTLYGNNTALAMASLTLASIGILTTLPLFW 363 VL+ RSAD RERRWH+AIPA G IGL+LS ++ NT LAMA+LTL ++GILTTLPLFW Sbjct: 311 VLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTLPLFW 370 Query: 364 SLPTAFLSGTAAAAGIALINSLGNLAGFVSPFLVGWLKDTTQSTNAGMYVLAASLVIGGL 423 SLPTAFL+GT AAAGIALINSLGNLAGF+SP+ VGWLKDTT+ST++GMY+LAAS+V+G L Sbjct: 371 SLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMVLGAL 430 Query: 424 LTLSLPAKLVNK 435 LTLS+PA+ VN+ Sbjct: 431 LTLSVPARTVNR 442 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 520 bits (1338), Expect = e-147, Method: Compositional matrix adjust. Identities = 254/419 (60%), Positives = 322/419 (76%) Query: 17 EDATYSKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAGIFFLGYF 76 E+ Y K W LLPLL LCYV +YLDRVNVGFAKLQM DL+FSDTVYGLGAG+FF+GYF Sbjct: 18 ENNAYRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQFSDTVYGLGAGMFFIGYF 77 Query: 77 VFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVSTPEMFYIMRFLLGVAEAGFFPGV 136 E+PSN+ILH+VGARLWIARIMITWGIIS MA+V+TP FY+MRFLLGVAEAGFFPG+ Sbjct: 78 FLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFYVMRFLLGVAEAGFFPGI 137 Query: 137 ILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQWMFILEAI 196 ILY++YW+P+ RRG++ LF+ + LSG+IG PLSGWIM G G+ GWQWMFILE I Sbjct: 138 ILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFNGFQGYAGWQWMFILEGI 197 Query: 197 PSLILGVLVILYMKDRIRDAEWLTEDEKRLLETNISHEESQKEHLSLGAMFANGRVWLGA 256 PS+++G+L+I +KDRI A WLT+ EK +L+TNI +E + H L F RVWL Sbjct: 198 PSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENEAAHYAHSRLRDAFLQPRVWLLT 257 Query: 257 LIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRSADARRER 316 LIYFC + G Y + FWLPT+I+ +GV D L++G LTAIP A AA M+++ RSAD RER Sbjct: 258 LIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAAAAVTMIVVSRSADRLRER 317 Query: 317 RWHVAIPAFIGCIGLLLSTLYGNNTALAMASLTLASIGILTTLPLFWSLPTAFLSGTAAA 376 RWH+A+ A +G +G++LST + +N +AM LT+ ++G L+T+PLFWSLPTAFL G+AAA Sbjct: 318 RWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALSTIPLFWSLPTAFLGGSAAA 377 Query: 377 AGIALINSLGNLAGFVSPFLVGWLKDTTQSTNAGMYVLAASLVIGGLLTLSLPAKLVNK 435 AGIA INS GNL GFV+P+++G+LKD TQST GM +++ +L IG L +PAK VN Sbjct: 378 AGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTLFIGAALVFLIPAKAVNH 436 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 464 bits (1195), Expect = e-130, Method: Compositional matrix adjust. Identities = 231/421 (54%), Positives = 317/421 (75%), Gaps = 4/421 (0%) Query: 17 EDATYSKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAGIFFLGYF 76 E+ TY KV +R++PLL +CY+ +YLDRVNVGFAKLQM ++L FS+ +YGLGAG+FF+GYF Sbjct: 33 ENMTYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYF 92 Query: 77 VFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVSTPEMFYIMRFLLGVAEAGFFPGV 136 FE+PSN++LHK+GARLWIARIMITWG++S A+V T FYI+RFLLG AEAGF+PGV Sbjct: 93 FFEIPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGV 152 Query: 137 ILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQWMFILEAI 196 ILYLTYW+P+ RRG + ALF G +G+ G PLSGWIM G GWQWMF+LEAI Sbjct: 153 ILYLTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAI 212 Query: 197 PSLILGVLVILYMKDRIRDAEWLTEDEKRLLETNISHEESQK--EHLSLGAMFANGRVWL 254 P+++LGV+++LY+ + ++ A+WLTE+EK ++ +I + K H SL ++ N +W+ Sbjct: 213 PAVVLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASH-SLMSLVKNPMLWV 271 Query: 255 GALIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRSADARR 314 LIYFCFVMG +G++ W+PT+I+A+GV+ + +GLL AIP+ A AMV+ RSAD R Sbjct: 272 MMLIYFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYR 331 Query: 315 ERRWHVAIPAFIGCIGLLLSTLYGNNTALAMASLTLASIGILTTLPLFWSLPTAFLSGTA 374 ERRWH+ +PA +G +G +++ NT +++ L++A+ G+L PLFWSLPTA LSG A Sbjct: 332 ERRWHLVVPALLGAVGFVVAA-SATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAA 390 Query: 375 AAAGIALINSLGNLAGFVSPFLVGWLKDTTQSTNAGMYVLAASLVIGGLLTLSLPAKLVN 434 AAAGIALINS+ NLAGF+SP++VG ++D T S+ GMYVLA L++G + L +PA VN Sbjct: 391 AAAGIALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLILGAAIVLCIPASKVN 450 Query: 435 K 435 + Sbjct: 451 R 451 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 398 bits (1022), Expect = e-110, Method: Compositional matrix adjust. Identities = 202/418 (48%), Positives = 289/418 (69%) Query: 17 EDATYSKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLGAGIFFLGYF 76 D+T+ +VTWRL+PLL +CYV ++LDR+N+GFAKLQM DL FSDTVYGLGAG+FF+ Y Sbjct: 15 SDSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTVYGLGAGLFFIAYA 74 Query: 77 VFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVSTPEMFYIMRFLLGVAEAGFFPGV 136 +F +PSN++L ++G R WIA +M+ WG +S AM V T FY++RFLLGVAEAGFFPG+ Sbjct: 75 LFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRFLLGVAEAGFFPGI 134 Query: 137 ILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGWQWMFILEAI 196 ++YL W+PA RRG+ITALF + ++GVIGGPLSGWI+ G GWQWMF++E + Sbjct: 135 LVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHDALGLRGWQWMFLIEGL 194 Query: 197 PSLILGVLVILYMKDRIRDAEWLTEDEKRLLETNISHEESQKEHLSLGAMFANGRVWLGA 256 P ++LGV+V + + WL++++K LL ++ EE +K S +F+N +VWL Sbjct: 195 PVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQRKTITSFSGIFSNPQVWLLV 254 Query: 257 LIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIGRSADARRER 316 IYF ++ + ++FW+P++I G++ +G+L+A+PY A M+ IGRS+D RER Sbjct: 255 AIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYLAGCAFMIFIGRSSDRLRER 314 Query: 317 RWHVAIPAFIGCIGLLLSTLYGNNTALAMASLTLASIGILTTLPLFWSLPTAFLSGTAAA 376 RWH+ IP + GL L+ L + L M L +A +G LP+FW LP AFLS A Sbjct: 315 RWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASAALPMFWQLPPAFLSSATLA 374 Query: 377 AGIALINSLGNLAGFVSPFLVGWLKDTTQSTNAGMYVLAASLVIGGLLTLSLPAKLVN 434 AGIALI+S G++A F++P+L+GW++DTTQS + +Y+LA + +G L L PA +VN Sbjct: 375 AGIALISSFGSIAAFLAPYLIGWMRDTTQSASLALYLLAILIALGAGLVLRTPAAVVN 432 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 365 bits (938), Expect = e-100, Method: Compositional matrix adjust. Identities = 192/403 (47%), Positives = 254/403 (63%), Gaps = 5/403 (1%) Query: 8 AADGARASFEDATYSKVTWRLLPLLFLCYVASYLDRVNVGFAKLQMLQDLKFSDTVYGLG 67 A G R++ + YS V R+LP L CY+ +YLDR+N+GFAKLQM DL SD YGLG Sbjct: 10 AHSGERST---SVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLG 66 Query: 68 AGIFFLGYFVFEVPSNMILHKVGARLWIARIMITWGIISGAMAYVSTPEMFYIMRFLLGV 127 AGIFF GY +FEVPSN++L K+GAR ++RI+I WGI+S +M +V+ FY +RFLLGV Sbjct: 67 AGIFFFGYMLFEVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGV 126 Query: 128 AEAGFFPGVILYLTYWYPAARRGKITALFMTGIALSGVIGGPLSGWIMHAMPGVWGHTGW 187 EAGF PG+I YLT WYP R + A+ + L GVIGGP S WIM G G GW Sbjct: 127 FEAGFAPGMIYYLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGW 186 Query: 188 QWMFILEAIPSLILGVLVILYMKDRIRDAEWLTEDEKRLLETNISHEESQKEHLSLGAMF 247 QWMF+ E IPS++LG+ Y+ D+ DA WLT+ +K ++ +I+ + S G Sbjct: 187 QWMFLAEGIPSILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIARAAPGQAS-SFGKAL 245 Query: 248 ANGRVWLGALIYFCFVMGLYGVSFWLPTIIKATGVSDPLNVGLLTAIPYAFAAAAMVLIG 307 ++++ A YFC + G+Y V FWLP+I+K+ G+SD +GL +AIP AM +G Sbjct: 246 TEPKLYVLAAAYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALG 305 Query: 308 RSADARRERRWHVAIPAFIGCIGLLLSTLYGNNTALAMASLTLASIGILTTLPLFWSLPT 367 R +D R ER H AI A +G GLL Y + A+ S+TLAS I + +FW++P Sbjct: 306 RRSDRRGERHLHSAITAVLGA-GLLAWAAYATSFPAALISITLASAAIFASYSVFWAIPQ 364 Query: 368 AFLSGTAAAAGIALINSLGNLAGFVSPFLVGWLKDTTQSTNAG 410 L GTAAA GIALINS+G GF SP L+GW K+ T S AG Sbjct: 365 QHLKGTAAAGGIALINSIGLFGGFFSPTLIGWTKEATGSLQAG 407