BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0088.p (448 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3403 [T] COG0642 Signal transduction histidine kinase Rso Ral... 425 e-119 NMA0670 [T] COG0642 Signal transduction histidine kinase NmA Nei... 270 4e-72 NMB1792 [T] COG0642 Signal transduction histidine kinase Nme Nei... 225 1e-58 RSc0549 [T] COG0642 Signal transduction histidine kinase Rso Ral... 175 2e-43 RSp1553 [T] COG0642 Signal transduction histidine kinase Rso Ral... 171 2e-42 >RSc3403 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 446 Score = 425 bits (1093), Expect = e-119, Method: Compositional matrix adjust. Identities = 225/415 (54%), Positives = 293/415 (70%), Gaps = 14/415 (3%) Query: 25 SALDESHELQDDMLRQIAHLMERQRLSSASPVPEVSYASSNEESRVIVQHL---GYSASK 81 SA E+HELQDD+LRQ+ + + Q L +AS +++ESRV+VQ L G A + Sbjct: 38 SAFSEAHELQDDVLRQVGAMFDPQHLPAAS----AEAPMADQESRVVVQLLPAPGADAGR 93 Query: 82 AEIDAEEALPLSSTLMDGLHDIDAAGENFRVLVQTMPSGERIAVAQESDFRNEIARDGAL 141 A A P STL DG+ A N+RV V+T+ G+RIAVAQE+ RNE AR+ AL Sbjct: 94 ASTRATPVFP--STLADGMQTARAGKYNYRVWVRTLADGQRIAVAQETAVRNETARNSAL 151 Query: 142 RTIMPFLLLVPVLLLIVADLIRKMFRPIAALSKEVDQRQDEQLHPVEVSHFPVEVRPFAV 201 T+MPFL+LVP+LLL +AD++RKMF PI L+ EVDQR + QLH + P EVRPF V Sbjct: 152 HTVMPFLILVPILLLAMADVLRKMFAPIRRLAHEVDQRDERQLHAIAPDAVPAEVRPFVV 211 Query: 202 AINRLLGRIDQSMASQRRFVADAAHELRSPMTAISLQAERLEEADMSEQARQRLRALREG 261 AINRLL R+ QS+ +Q RFVADAAHELR+P+TA+SLQAERL EA MS A++RL ALR+G Sbjct: 212 AINRLLARVAQSVQAQHRFVADAAHELRTPLTALSLQAERLGEAPMSAAAQERLAALRQG 271 Query: 262 IDRGRNLLNQLLALAKAQSSVSAVATPISVQTIYRRVLEDLMPLAESKQIDIGVDGQRDA 321 I+R R LL QLL LA+AQ+ A A +SVQ ++R VLEDLMPLAE+K++D+GV DA Sbjct: 272 IERSRALLEQLLTLARAQADTQAPAGAVSVQRVFRSVLEDLMPLAEAKRLDLGVTTDADA 331 Query: 322 RLLVGELDLFALVRNLADNAVRYTPNGGKVDLALEFEDENVVLIVEDSGPGIPVVERARI 381 R+ GELDLF ++RNL DNA+RYTP+GG +DL+L+ + + + V+D+GPGIP ERAR+ Sbjct: 332 RVRAGELDLFVILRNLVDNAIRYTPDGGSIDLSLQTDGDLAHITVQDTGPGIPASERARV 391 Query: 382 FEAFHRLLGSNQIGSGLGLSIVKAIADRLGASITLGFRDES--DRSGLRVAVSIP 434 F+AF+R+LG+ GSGLGLSIV + RLG + L DE+ SGLR V +P Sbjct: 392 FDAFYRVLGNGATGSGLGLSIVGTLVQRLGGEVAL---DEAAGTASGLRATVRLP 443 >NMA0670 [T] COG0642 Signal transduction histidine kinase NmA Neisseria meningitidis Z2491 Length = 416 Score = 270 bits (691), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 161/406 (39%), Positives = 251/406 (61%), Gaps = 19/406 (4%) Query: 14 VAIVAGVFSFVSALDESHELQDDMLRQIAHLMERQRLSSASPVPEVSYASSNEESRVIVQ 73 +A++AG+FS+ E+ LQDD+LRQ A + S +PE + ++R+ VQ Sbjct: 5 LAMLAGMFSYYETFHETEALQDDLLRQAALYVAPD--SKPETLPE-----GDGDTRIFVQ 57 Query: 74 HLGYSASKAEIDAEEALPLSSTLMDGLHDIDAAGEN--FRVLVQTMPSGERIAVAQESDF 131 + D +LP + L DGLH + A G++ +RV ++T G RIAV QE+++ Sbjct: 58 ------MPQQEDPVVSLP--AHLADGLHTLQADGDDDYYRVYIRTTEQG-RIAVMQENEY 108 Query: 132 RNEIARDGALRTIMPFLLLVPVLLLIVADLIRKMFRPIAALSKEVDQRQDEQLHPVEVSH 191 R ++A D A ++++P L +P+++L+ + K RP+ LS+ ++QR+ L + V + Sbjct: 109 REDLAADAARQSVLPLLAALPLMILLTVWITHKAMRPVRKLSQSLEQRRINDLSALSVDN 168 Query: 192 FPVEVRPFAVAINRLLGRIDQSMASQRRFVADAAHELRSPMTAISLQAERLEEADMSEQA 251 P E+R F AIN LL R D+ + ++RFVADAAHELR+PMTA+SLQAERL + A Sbjct: 169 IPSEIRGFVTAINLLLKRADEDIRHRQRFVADAAHELRTPMTALSLQAERLNNMSLPPDA 228 Query: 252 RQRLRALREGIDRGRNLLNQLLALAKAQSSVSAVA-TPISVQTIYRRVLEDLMPLAESKQ 310 ++ L++ I R ++LL QLLALA++QS + + T +Q+ +R+VL++LMPLA K+ Sbjct: 229 ARQPAVLQQSIRRNKHLLEQLLALARSQSDETPLTKTTFGLQSRFRQVLQELMPLALEKR 288 Query: 311 IDIGVDGQRDARLLVGELDLFALVRNLADNAVRYTPNGGKVDLALEFEDENVVLIVEDSG 370 DIGV D + E +++ L++ ADNAVRYTP G++DL E + + + VED+G Sbjct: 289 QDIGVAVGGDVEVSADETEIYTLIKTFADNAVRYTPPEGRIDLGFTDEGKYLAVWVEDNG 348 Query: 371 PGIPVVERARIFEAFHRLLGSNQIGSGLGLSIVKAIADRLGASITL 416 GIP ERAR+ + F+R+LG+ Q G+GLGLSI +A + G + L Sbjct: 349 NGIPESERARVLDPFYRILGTEQQGTGLGLSIADTLAKKYGGHLEL 394 >NMB1792 [T] COG0642 Signal transduction histidine kinase Nme Neisseria meningitidis MC58 Length = 314 Score = 225 bits (574), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 122/291 (41%), Positives = 188/291 (64%), Gaps = 1/291 (0%) Query: 127 QESDFRNEIARDGALRTIMPFLLLVPVLLLIVADLIRKMFRPIAALSKEVDQRQDEQLHP 186 QE+++R ++A D A ++++P L +P+++L+ + K RP+ LS+ ++QR+ L Sbjct: 2 QENEYREDLAADAARQSVLPLLAALPLMILLTVWITHKAMRPVRKLSQSLEQRRINDLSA 61 Query: 187 VEVSHFPVEVRPFAVAINRLLGRIDQSMASQRRFVADAAHELRSPMTAISLQAERLEEAD 246 + V + P E+R F AIN LL R D+ + ++RFVADAAHELR+PMTA+ LQAERL Sbjct: 62 LSVDNIPSEIRGFVTAINLLLKRADEDIRHRQRFVADAAHELRTPMTALPLQAERLNNMP 121 Query: 247 MSEQARQRLRALREGIDRGRNLLNQLLALAKAQSS-VSAVATPISVQTIYRRVLEDLMPL 305 + A ++ L++ I R ++LL QLLALA++QS + T +Q+ +R+VL++LMPL Sbjct: 122 LPPDAARQPAVLQQSIRRNKHLLEQLLALARSQSDEIPLTKTTFGLQSRFRQVLQELMPL 181 Query: 306 AESKQIDIGVDGQRDARLLVGELDLFALVRNLADNAVRYTPNGGKVDLALEFEDENVVLI 365 A K DIGV D + E +++ L++ ADNAVRYTP G++DL E + + + Sbjct: 182 ALEKCQDIGVAVGGDVEVSADETEIYTLIKTFADNAVRYTPPEGRIDLGFTDEGKYLAVW 241 Query: 366 VEDSGPGIPVVERARIFEAFHRLLGSNQIGSGLGLSIVKAIADRLGASITL 416 VED+G GIP ERAR+ + F+R+LG+ Q G+GLGLSI +A + G + L Sbjct: 242 VEDNGKGIPESERARVLDPFYRILGTEQQGTGLGLSIADTLAKKYGGYLEL 292 >RSc0549 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 513 Score = 175 bits (444), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 119/387 (30%), Positives = 205/387 (52%), Gaps = 17/387 (4%) Query: 64 SNEESRVIVQHLGYSASKAEIDAEEALPLSSTLMDG----LHDIDAAGENFRV-LVQTMP 118 ++E + Q LG S D + LP G L D G RV Sbjct: 118 ADETDNIYYQVLGSSGEFVSGDRDLPLPPEEDAGAGSLVQLRDDRIHGAEIRVAYTYVQQ 177 Query: 119 SGERIA---VAQESDFRNEIARDGALRTIMPFLLLVPVLLLIVADLIRKMFRPIAALSKE 175 G R A VA+ D R ++A + I+P +++P+ +++V + + P+ A+ + Sbjct: 178 PGARPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFGLTRGLAPLNAIQER 237 Query: 176 VDQRQDEQLHPVEVSHFPVEVRPFAVAINRLLGRIDQSMASQRRFVADAAHELRSPMTAI 235 + R P++ P E+ P + N LLGR++QS+ +Q+RF+ADAAH++++P+ + Sbjct: 238 IRARSPGDTSPIDEGAAPQELTPLVASFNELLGRLEQSVQTQKRFIADAAHQMKTPLAGL 297 Query: 236 SLQAERLEEADMSEQARQRLRALREGIDRGRNLLNQLLALAKAQSSVSAVA-TPISVQTI 294 +QAE + ++ R+ L + + +R +L+ QLL+LA+ ++ +A P+ + + Sbjct: 298 RMQAELAQREQSPDELRRTLAHIADSSERTAHLVKQLLSLARMENMGAADGMVPLDLCAL 357 Query: 295 YRRVLEDLMPLAESKQIDIGVDGQRDARLLVGELDLFA-LVRNLADNAVRYTPNGGKVDL 353 R+V+ + +P A +KQID+G + G + A ++ NL DNA+RYTP+GG V + Sbjct: 358 SRQVVAEWLPKAWAKQIDLGFEEPGAPVTTSGNATMLAEMLNNLLDNAIRYTPDGGHVTV 417 Query: 354 AL---EFEDENVVLIVEDSGPGIPVVERARIFEAFHRLLGSNQIGSGLGLSIVKAIADRL 410 + FE V L VED+GPGIP ER R+ + F+R+LG+ GSGLGL+IV+ I + Sbjct: 418 RVTTAPFE-PFVFLDVEDTGPGIPAGERERVMQRFYRILGTQAEGSGLGLAIVREIVQQH 476 Query: 411 GASITL---GFRDESDRSGLRVAVSIP 434 G I + ++ +G R +++P Sbjct: 477 GGDIAVLDYVYQSSPRLAGARFRITLP 503 >RSp1553 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 438 Score = 171 bits (434), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 137/423 (32%), Positives = 217/423 (51%), Gaps = 14/423 (3%) Query: 16 IVAGVFSFVSALDESHELQDDMLRQIAHLMERQRLSSASPVPEVSYASSNEESRVIVQHL 75 + A + + A E++ L D ++Q+A + Q + P P ++++ VI Sbjct: 21 VAATLLIYAQARQEANALFDYQMQQVAAALPSQWID---PPPPALAGIAHDDDVVIRIWD 77 Query: 76 GYSASKAEIDAEEALPLSSTLMDGLHDIDAAGENFRVL-VQTMPSGERIAVAQESDFRNE 134 S A LP + L G D+ +RV V P+ + +AQ R+E Sbjct: 78 DTGRSLYLSHARPDLPTQAEL--GFSDVVTPEGTWRVYSVAFGPA--VVQIAQPYSARHE 133 Query: 135 IARDGALRTIMPFLLLVPVLLLIVADLIRKMFRPIAALSKEVDQRQDEQLHPVEVSHFPV 194 +A ALRT+ P L+L+P+L +V + + P+ ++++V R L P+ P Sbjct: 134 VAARMALRTVAPLLILLPLLAWLVWLAVGRGLSPLGTVARQVQTRDAAALSPLPTHGLPA 193 Query: 195 EVRPFAVAINRLLGRIDQSMASQRRFVADAAHELRSPMTAISLQAERLEEADMSEQARQR 254 E+RP A+N LL R+ ++A QR FVADAAH LR+P+ A+ LQ + + A ++ R Sbjct: 194 EIRPLTTALNDLLARLGGALAHQRAFVADAAHALRTPLAALKLQLQVADRAQSEDERRAA 253 Query: 255 LRALREGIDRGRNLLNQLLALAKAQSSVSAVA-TPISVQTIYRRVLEDLMPLAESKQIDI 313 L G++R L+ QLL LA+ + + P+++ I V+ +L P A K+ID+ Sbjct: 254 HADLHRGVERMIRLVGQLLTLARQEPGAADTQRGPVALDVIAAEVVAELSPAALQKRIDL 313 Query: 314 GVDGQRDARLLVGELD-LFALVRNLADNAVRYTPNGGKVDLAL-EFEDENVVLIVEDSGP 371 G+ + + G D L L+ NL DNA+ Y P G +VD++ D LIVED+GP Sbjct: 314 GIAVESQPASVGGNADALRVLLVNLVDNALCYCPEGARVDVSTGHAPDGGAQLIVEDNGP 373 Query: 372 GIPVVERARIFEAFHRLLGSNQIGSGLGLSIVKAIADRLGASITLGFRDESDRSGLRVAV 431 GIP ER R+ + F+R + GSGLGL+IV+ IA A+++L R+ GLRV + Sbjct: 374 GIPAAERERVLDRFYRPAQAPTGGSGLGLAIVREIAQAHDATLSLEAREG---GGLRVVL 430 Query: 432 SIP 434 P Sbjct: 431 RFP 433