BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0080.p (410 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1445 [GEPR] COG0477 Permeases of the major facilitator superf... 545 e-155 all7627 [GEPR] COG0477 Permeases of the major facilitator superf... 352 8e-97 PAB0874 [GEPR] COG0477 Permeases of the major facilitator superf... 168 2e-41 MJ1317 [GEPR] COG0477 Permeases of the major facilitator superfa... 167 3e-41 PH0718 [GEPR] COG0477 Permeases of the major facilitator superfa... 157 3e-38 >RSc1445 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 400 Score = 545 bits (1403), Expect = e-155, Method: Compositional matrix adjust. Identities = 282/390 (72%), Positives = 324/390 (83%), Gaps = 11/390 (2%) Query: 6 STLGKIPASVWILGGVSMLMDISSEMIHSLLPLFMISTLGASAFAVGVVEGLAESTALIV 65 L ++P +W+LGGVS+LMD++SEMIHSLLP+FM+S LGASA VG+VEGLAESTALIV Sbjct: 8 DVLRRLPPGIWVLGGVSLLMDVASEMIHSLLPMFMVSALGASALTVGLVEGLAESTALIV 67 Query: 66 KIFSGALSDYFGKRKGLALFGYTLGALTKPLFAIAPTTGIVLTARLLDRVGKGLRGAPXN 125 KIFSGALSDY G+RKGLA+FGY LGA++KPLFA+APT G+VL ARLLDRVGKG+RGAP Sbjct: 68 KIFSGALSDYLGRRKGLAVFGYALGAVSKPLFALAPTAGLVLAARLLDRVGKGVRGAP-- 125 Query: 126 SNSTFSVAPRDALVADVTPPEIRGAAFGLRQSLDTIGAFLGPLLAVGLMLMWANDFRAVF 185 RDALVAD+ PPE+RGAAFGLRQSLDT+GAFLGPLLAVGLML WANDFRAVF Sbjct: 126 ---------RDALVADIAPPELRGAAFGLRQSLDTVGAFLGPLLAVGLMLRWANDFRAVF 176 Query: 186 WVAVLPGFLAVILLIIGIKEPSRRSTEKRTNPFRRDKLKRLSPAYWWVVTIGAVFVLARF 245 WVAV+PG L+V LL G++EP+ R+ R NP RR L+RL+ AYWWVV IGAVF LARF Sbjct: 177 WVAVVPGLLSVALLAFGLREPAARAATHRANPIRRANLRRLTRAYWWVVAIGAVFTLARF 236 Query: 246 SEAFLVLKAQKSGVPLALIPLIMVAMNVVYAACAYPFGTLSDRMSHSTMLAFGLVALIMS 305 SEAFLVL+AQ+ GVP+AL+PL+MVAMNVVYA AYPFG LSDR+SH+ +LA GLV LI + Sbjct: 237 SEAFLVLRAQRGGVPIALVPLVMVAMNVVYALSAYPFGKLSDRVSHTGLLALGLVVLIAA 296 Query: 306 DLTLAAGDHWLGLGVGVALWGVHMGMTQGLLATMVAATAPADLRGTAYGFFNLVSGIAML 365 DL L A DHW + GVALWGVHMG+TQGLLATMVA TAPADLRGTAYG FNLVSGIAML Sbjct: 297 DLVLGATDHWGAVLAGVALWGVHMGITQGLLATMVADTAPADLRGTAYGAFNLVSGIAML 356 Query: 366 LASVVAGLLWDYVGPSATFLAGAAFSLLAL 395 +AS +AG LWD G +ATF AGA F LAL Sbjct: 357 VASALAGWLWDAHGAAATFHAGAVFCGLAL 386 >all7627 [GEPR] COG0477 Permeases of the major facilitator superfamily Nos Nostoc sp. PCC 7120 Length = 399 Score = 352 bits (904), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 200/406 (49%), Positives = 270/406 (66%), Gaps = 15/406 (3%) Query: 4 SNSTLGKIPASVWILGGVSMLMDISSEMIHSLLPLFMISTLGASAFAVGVVEGLAESTAL 63 + T IP +VW+LG VS+L DISSEMIHS+LPLF++S LGA+ VG +EG+AESTA Sbjct: 2 TTKTFQTIPRNVWVLGFVSLLTDISSEMIHSVLPLFLVSALGANLLTVGWIEGIAESTAS 61 Query: 64 IVKIFSGALSDYFGKRKGLALFGYTLGALTKPLFAIAPTTGIVLTARLLDRVGKGLRGAP 123 ++K+FSGALSDY G+RK LA+ GY L L KPLFA+A + VL AR DRVGKG+R Sbjct: 62 VLKVFSGALSDYLGQRKKLAVVGYGLSTLVKPLFALATSPAWVLMARFGDRVGKGIR--- 118 Query: 124 XNSNSTFSVAPRDALVADVTPPEIRGAAFGLRQSLDTIGAFLGPLLAVGLMLMWANDFRA 183 VAPRDA+VADVT RGAA+GLRQSLDTIGAF GPL+A LM +FR Sbjct: 119 --------VAPRDAIVADVTDSVNRGAAYGLRQSLDTIGAFTGPLVAFILMSFSGQNFRL 170 Query: 184 VFWVAVLPGFLAVILLIIGIKEPSRRSTEKRTNPFRRDKLKRLSPAYWWVVTIGAVFVLA 243 VFW+AVLPG LAV LL G++EP R+ ++ NP L+ L +YW +V + +F L Sbjct: 171 VFWLAVLPGILAVALLATGVREPDNRNNRRQNNPLHWSALQSLGKSYWVLVVVALLFNLG 230 Query: 244 RFSEAFLVLKAQKSGVPLALIPLIMVAMNVVYAACAYPFGTLSDRMSHSTMLAFGLVALI 303 S+AFL+L+AQ++GV +L+PL +V MN+ Y+ AYP G LSDR+ +L G Sbjct: 231 NSSDAFLLLQAQQAGVSASLVPLTLVVMNIAYSLSAYPVGLLSDRIGRLGLLVGGFCVYA 290 Query: 304 MSDLTLA-AGDHWLGLGVGVALWGVHMGMTQGLLATMVAATAPADLRGTAYGFFNLVSGI 362 ++ L A W G+ L+G++ GM+QG+L +VA P+ LRGTA+G NL +G+ Sbjct: 291 LAYLGFAFVNAPWQVWGL-FGLYGLYQGMSQGILLALVADRVPSHLRGTAFGLINLATGV 349 Query: 363 AMLLASVVAGLLWDYVGPSATFLAGAAFSL--LALLGIWIKVRKTS 406 A+L AS++ G+LW + P ATF+ G+ F+L +ALL ++ R+ S Sbjct: 350 ALLPASLLGGVLWQTISPKATFITGSIFALSAIALLLVFEGGRRKS 395 >PAB0874 [GEPR] COG0477 Permeases of the major facilitator superfamily Pab Pyrococcus abyssi Length = 392 Score = 168 bits (425), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 114/399 (28%), Positives = 205/399 (51%), Gaps = 25/399 (6%) Query: 14 SVWILGGVSMLMDISSEMIHSLLPLFMISTLGASAFAVGVVEGLAESTALIVKIFSGALS 73 +V++LG VS L D+SSEMI ++P ++ L A G + GL ES + + K+ G +S Sbjct: 12 NVFLLGLVSFLNDMSSEMIAPIVPSYLTDILKIGKLASGSIMGLIESLSSLFKVLFGYIS 71 Query: 74 DYFGKRKGLALFGYTLGALTKPLFAIAPTTGIVLTARLLDRVGKGLRGAPXNSNSTFSVA 133 D F KRK GY + ++K A+ + L R+LDR+GKG+R A Sbjct: 72 DKFRKRKAFVALGYLISTISKGALAVTHSWWDFLILRILDRIGKGIR-----------TA 120 Query: 134 PRDALVADVTPPEIRGAAFGLRQSLDTIGAFLGPLLAVGLMLMWAN-----DFRAVFWVA 188 PRDAL+A+ + G +FG + +DT+GA GPL+A+GL+ + AN +R +F ++ Sbjct: 121 PRDALIAESSEKGKSGKSFGFHRMMDTLGAVAGPLVAMGLLALLANYPKELAYRYIFLIS 180 Query: 189 VLPGFLAVILLIIGIKEPSRRSTEKRT--NPFRRDKLKRLSPAYWWVVTIGAVFVLARFS 246 +PG + V+++++ +K+ +K + + L+ + I A+ L R+S Sbjct: 181 AVPGVIGVLIVLLLVKDKGSEVKKKIKGISALKSSNLRIF-------LVIVAIAALGRYS 233 Query: 247 EAFLVLKAQKSGVPLALIPLIMVAMNVVYAACAYPFGTLSDRMSHSTMLAFGLVALIMSD 306 AF + KA++ G + NV+YA AYP G SD++ ++ G ++ Sbjct: 234 YAFTLWKAEELGYSVFQGLGFYALFNVIYALSAYPIGYYSDKVGKKIIITIGFGIAGLAS 293 Query: 307 LTLAAGDHWLGLGVGVALWGVHMGMTQGLLATMVAATAPADLRGTAYGFFNLVSGIAMLL 366 L A ++ L + L+G++M + + +A A +GT G ++ V G+ + Sbjct: 294 LIFAYANNLPTLLLAFVLYGLYMAIEDTIPRAYMADLAKEFEKGTVIGAYHTVFGVFVFP 353 Query: 367 ASVVAGLLWDYVGPSATFLAGAAFSLLALLGIWIKVRKT 405 AS++ G LW + FL A +++A++ + + ++++ Sbjct: 354 ASIIVGYLWQTYSLTVGFLYSAVMNVIAMIMMALLIKES 392 >MJ1317 [GEPR] COG0477 Permeases of the major facilitator superfamily Mja Methanococcus jannaschii Length = 398 Score = 167 bits (424), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 123/401 (30%), Positives = 210/401 (52%), Gaps = 26/401 (6%) Query: 1 MSNSNSTLGKIPASVWILGGVSMLMDISSEMIHSLLPLFMISTLGASAFAVGVVEGLAES 60 + +N ++ +V++LG S L D+SSEMI +LP+ +I+++G + ++G+V GL E Sbjct: 10 LQKNNENDRELSKNVYLLGFTSFLNDMSSEMIMPILPM-LITSVGGGSLSIGLVGGLREF 68 Query: 61 TALIVKIFSGALSDYFGKRKGLALFGYTLGALTKPLFAIAPT-TGIVLTARLLDRVGKGL 119 + I+ + G SD KRK + GY ++ K L ++ + G V+ + L +R+GKG+ Sbjct: 69 ISNILMVLIGYCSDKVRKRKIFVVLGYLTSSMFKLLLGLSKSWLGAVIFSSL-ERMGKGI 127 Query: 120 RGAPXNSNSTFSVAPRDALVADVTPPEIRGAAFGLRQSLDTIGAFLGPLLAVGLMLMWAN 179 R APRDA++++ + P+ G FG++++ DT GA LG L++ +L Sbjct: 128 R-----------TAPRDAIISE-SMPKTLGKGFGIQRAFDTAGAILGSTLSLLFILYLQY 175 Query: 180 DFRAVFWVAVLPGFLAVILLIIGIKEPSRRSTEKRTNPFRRDKLKRLSPAYWWVVTIGAV 239 F + +A + GFL +I L +KE S K T R +K L + I A+ Sbjct: 176 SFNQIILIAAVIGFLTLIPLYF-VKEKPSPSNNKIT---FRVGIKNLPKELKLFILISAI 231 Query: 240 FVLARFSEAFLVLKAQKSGVPL-----ALIPL-IMVAMNVVYAACAYPFGTLSDRMSHST 293 F L+ FS F +L+AQ+ + + +IP+ + + N+ YA + PFG LSD++ + Sbjct: 232 FTLSNFSYMFYILRAQEFLMIVDEKMAIIIPIALYILYNIFYATFSIPFGILSDKIGRKS 291 Query: 294 MLAFGLVALIMSDLTLAAGDHWLGLGVGVALWGVHMGMTQGLLATMVAATAPADLRGTAY 353 +L G + + L A L + AL+G+ + G V+ + D+R TA Sbjct: 292 VLTIGYIVYGIVSLGFAYFISQKSLILLFALYGIAYALFAGNQKAYVSDLSSEDIRATAL 351 Query: 354 GFFNLVSGIAMLLASVVAGLLWDYVGPSATFLAGAAFSLLA 394 G F V G+ L AS++AG LW + P TFL G+ ++++ Sbjct: 352 GLFYTVVGLTSLPASLIAGYLWK-ISPEMTFLYGSVLAIIS 391 >PH0718 [GEPR] COG0477 Permeases of the major facilitator superfamily Pho Pyrococcus horikoshii Length = 398 Score = 157 bits (398), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 123/410 (30%), Positives = 202/410 (49%), Gaps = 27/410 (6%) Query: 3 NSNSTLGKIPASVWILGGVSMLMDISSEMIHSLLPLFMISTLGASAFAVGVVEGLAESTA 62 + I +V++LG VS L D+SSEMI ++P ++ L A G + GL ES + Sbjct: 5 EKERKIAGISWNVFLLGLVSFLNDMSSEMIAPIVPTYLTDILKMGKLASGSIMGLIESLS 64 Query: 63 LIVKIFSGALSDYFGKRKGLALFGYTLGALTKPLFAIAPTTGIVLTARLLDRVGKGLRGA 122 + K+ G +SD F KRK GY L + K A+ + LT R+LDR+GKG+R Sbjct: 65 SLFKVIFGYISDVFRKRKTFVALGYLLSTIAKGALALTHSWWDFLTLRILDRIGKGIR-- 122 Query: 123 PXNSNSTFSVAPRDALVADVTPPEIRGAAFGLRQSLDTIGAFLGPLLAVGLMLMWAN--- 179 APRDAL+A+ + G +FG + +DT+GA GPL+AVGL+ + + Sbjct: 123 ---------TAPRDALIAESSEKGKSGKSFGFHRMMDTLGAVTGPLVAVGLLALLSKYPK 173 Query: 180 --DFRAVFWVAVLPGFLAVILLIIGIKEPS--RRSTEKRTNPFRRDKLKRLSPAYWWVVT 235 +R +F ++ +PG + V+++I +K+ + K + + L+ A+ VV Sbjct: 174 ELAYRYIFLISAIPGAIGVLIVIFLVKDRGGIVKKKIKEISSLKSPHLR----AFLAVVA 229 Query: 236 IGAVFVLARFSEAFLVLKAQKSGVPLALIPLIMVAMNVVYAACAYPFGTLSDRMSHSTML 295 I A L R+S AF + K ++ G + NV+YA AYP G+ SD++ ++ Sbjct: 230 IAA---LGRYSYAFTLWKVKELGYSIFQGLEFYALFNVIYALAAYPIGSYSDKVGKKKII 286 Query: 296 AFGLVALIMSDLTLAAGDHWLGLGVGVALWGVHMGMTQGLLATMVAATAPADLRGTAYGF 355 G ++ L A L + L+GV+M + + +A A +GT G Sbjct: 287 TTGFGIAGLASLLFAYSKSLAMLMLAFILYGVYMAIEDTIPRAYMADLAKEYEKGTIIGM 346 Query: 356 FNLVSGIAMLLASVVAGLLWDYVGPSATFLAGAAFSLLA--LLGIWIKVR 403 ++ V GI + AS++ G LW FL + + +A L+G ++K + Sbjct: 347 YHTVFGIFVFPASIIVGYLWQTYSLEIGFLYASVMNFIAMILMGTFVKEK 396