BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0061.p (258 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0140 [L] COG0708 Exonuclease III Rso Ralstonia solanacearum 360 2e-99 NMB2082 [L] COG0708 Exonuclease III Nme Neisseria meningitidis MC58 350 2e-96 NMA0348 [L] COG0708 Exonuclease III NmA Neisseria meningitidis Z... 350 2e-96 XF0164 [L] COG0708 Exonuclease III Xfa Xylella fastidiosa 9a5c 271 1e-72 TP0125 [L] COG0708 Exonuclease III Tpa Treponema pallidum 223 2e-58 >RSc0140 [L] COG0708 Exonuclease III Rso Ralstonia solanacearum Length = 261 Score = 360 bits (923), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 170/257 (66%), Positives = 204/257 (79%), Gaps = 3/257 (1%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEDFLAPAGYVGHFHY 60 M +I+SANLNG+RSAA KGFFEW+ K+ DFVCVQELK DMT +FLAP GY G F + Sbjct: 1 MLRIISANLNGVRSAASKGFFEWMGKQDADFVCVQELKCAQDDMTPEFLAPHGYHGVFQH 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A KKGYSG G+Y+R QPD V +GF EFD EGRYVE YG L++IS+Y PSGSS EERQ Sbjct: 61 AVKKGYSGAGLYARHQPDDVIVGFDGGEFDAEGRYVEARYGKLSIISVYVPSGSSGEERQ 120 Query: 121 EAKFRFMEAFLPHLMEL-EKSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWM 179 +AK+RFM+ F+ HL +L + GREVV+CGD NI HKEID+KNWK NQKNSG LPEERAW+ Sbjct: 121 QAKYRFMDLFMQHLTDLRHEKGREVVLCGDVNIVHKEIDIKNWKGNQKNSGCLPEERAWL 180 Query: 180 TRIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAA 239 TR+FD++G VDV+R L P E YTWWSNRGQA+A NVGWRIDY ++TPGIAA A S + Sbjct: 181 TRLFDEVGYVDVFRTLDPRP--EQYTWWSNRGQAYAKNVGWRIDYQIATPGIAATARSTS 238 Query: 240 IYKEQRFSDHAPLTVVY 256 I+++ +FSDHAPLTV Y Sbjct: 239 IFRDIKFSDHAPLTVDY 255 >NMB2082 [L] COG0708 Exonuclease III Nme Neisseria meningitidis MC58 Length = 259 Score = 350 bits (897), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 160/256 (62%), Positives = 204/256 (79%), Gaps = 2/256 (0%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEDFLAPAGYVGHFHY 60 M KI+SAN+NGIRSA KKGF+E++ D VCVQELKAQ AD++ D P G GH+H Sbjct: 1 MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHC 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+K+GYSGV VYS+R+PD+V+IG G EFD EGR+V CD+G L+VISLY PSGSS+EERQ Sbjct: 61 AEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEKSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 + K+RF++AF P L ++ GR++V+CGDWNIAH+ IDLKNWK NQKNSGFLPEER W+ Sbjct: 121 QVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIG 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 ++ +LG D++R L+P+ G YTWWSNRGQA+A +VGWRIDY + TP +AAKAVSA + Sbjct: 181 KVIHKLGWTDMWRTLYPDVPG--YTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHV 238 Query: 241 YKEQRFSDHAPLTVVY 256 YK+++FSDHAPL V Y Sbjct: 239 YKDEKFSDHAPLVVEY 254 >NMA0348 [L] COG0708 Exonuclease III NmA Neisseria meningitidis Z2491 Length = 259 Score = 350 bits (897), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 160/256 (62%), Positives = 204/256 (79%), Gaps = 2/256 (0%) Query: 1 MPKIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEDFLAPAGYVGHFHY 60 M KI+SAN+NGIRSA KKGF+E++ D VCVQELKAQ AD++ D P G GH+H Sbjct: 1 MLKIISANVNGIRSAYKKGFYEYIAASGADIVCVQELKAQEADLSADMKNPHGMHGHWHC 60 Query: 61 AQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQ 120 A+K+GYSGV VYS+R+PD+V+IG G EFD EGR+V CD+G L+VISLY PSGSS+EERQ Sbjct: 61 AEKRGYSGVAVYSKRKPDNVQIGMGIEEFDREGRFVRCDFGRLSVISLYLPSGSSAEERQ 120 Query: 121 EAKFRFMEAFLPHLMELEKSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMT 180 + K+RF++AF P L ++ GR++V+CGDWNIAH+ IDLKNWK NQKNSGFLPEER W+ Sbjct: 121 QVKYRFLDAFYPMLEAMKNEGRDIVVCGDWNIAHQNIDLKNWKGNQKNSGFLPEEREWIG 180 Query: 181 RIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKAVSAAI 240 ++ +LG D++R L+P+ G YTWWSNRGQA+A +VGWRIDY + TP +AAKAVSA + Sbjct: 181 KVIHKLGWTDMWRTLYPDVPG--YTWWSNRGQAYAKDVGWRIDYQMVTPELAAKAVSAHV 238 Query: 241 YKEQRFSDHAPLTVVY 256 YK+++FSDHAPL V Y Sbjct: 239 YKDEKFSDHAPLVVEY 254 >XF0164 [L] COG0708 Exonuclease III Xfa Xylella fastidiosa 9a5c Length = 266 Score = 271 bits (693), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 141/265 (53%), Positives = 169/265 (63%), Gaps = 13/265 (4%) Query: 3 KIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEDFLAPAGYVGHFHYAQ 62 +I S N NG+RSA KGFF+W + D +CVQE KAQ + PAGY F A Sbjct: 2 RISSFNANGLRSALSKGFFDWFSTQDIDVLCVQETKAQRQQLVGPDFFPAGYHVCFRDAT 61 Query: 63 -KKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSSSEERQE 121 KKGYSGV +YSR +PD +R G EFD+EGRYVE +G+L+V+S Y PSGSS E+RQ Sbjct: 62 TKKGYSGVAIYSRCEPDELRTTLGWAEFDEEGRYVEARFGNLSVVSFYIPSGSSGEQRQH 121 Query: 122 AKFRFMEAFLPHLMELEKSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEERAWMTR 181 KF M P L E SGR+ V+CGDWNI +D++NWKSNQKNSG LP ER W+ Sbjct: 122 YKFEVMRWLRPILCEWLLSGRDYVLCGDWNIVRSALDIRNWKSNQKNSGCLPLERDWLNG 181 Query: 182 IF-DQL---------GLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGI 231 + D L G VD YR L+P+ GE YTWWSNRG A NNVGWRIDY +PG+ Sbjct: 182 LCADSLHEVNAAQGRGWVDTYRVLYPQ--GEDYTWWSNRGAARVNNVGWRIDYQFVSPGL 239 Query: 232 AAKAVSAAIYKEQRFSDHAPLTVVY 256 + AIY+EQRFSDHAP TV Y Sbjct: 240 RERVSRCAIYREQRFSDHAPYTVEY 264 >TP0125 [L] COG0708 Exonuclease III Tpa Treponema pallidum Length = 264 Score = 223 bits (569), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 115/263 (43%), Positives = 158/263 (60%), Gaps = 11/263 (4%) Query: 3 KIVSANLNGIRSAAKKGFFEWLQKEAPDFVCVQELKAQAADMTEDFLAP-----AG--YV 55 +I+S N+NGIR+ +K F WL +EAPD +C+QE+KA + ++ AP AG Y Sbjct: 6 RIISWNVNGIRAIERKDFLSWLAREAPDVLCLQEIKAHESQLSAALRAPVWSAGAGGTYY 65 Query: 56 GHFHYAQKKGYSGVGVYSRRQPDSVRIGFGNTEFDDEGRYVECDYGDLTVISLYAPSGSS 115 +FH AQ+ GYSG ++S+R PD+VR FG FD EGR + +G+LTV+S Y P+ Sbjct: 66 TYFHSAQRPGYSGTALFSKRAPDAVRF-FGVPAFDCEGRMLAARFGELTVVSAYFPNAQE 124 Query: 116 SEERQEAKFRFMEAFLPHLMELEKSGREVVICGDWNIAHKEIDLKNWKSNQKNSGFLPEE 175 +R K F AF E +G+ V++CGD+NIAHKEIDL + + N+ N GFLP+E Sbjct: 125 GGKRLAYKLDFCAAFRAFCDEERTAGQHVILCGDYNIAHKEIDLAHPQENEGNPGFLPQE 184 Query: 176 RAWMTRIFDQLGLVDVYRRLHPETTGEAYTWWSNRGQAWANNVGWRIDYHVSTPGIAAKA 235 RAWM F + G D +R E G+ YTWWS R +A A N+GWRIDY A+ Sbjct: 185 RAWMD-TFTEAGYADSFRAFCTE--GQQYTWWSYRARARARNIGWRIDYQCVDQAFLARV 241 Query: 236 VSAAIYKEQRFSDHAPLTVVYSD 258 S+ I E SDH P+ + Y+D Sbjct: 242 TSSQILSEVTGSDHCPVCLTYAD 264