BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0044.p (187 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0261 [E] COG0119 Isopropylmalate/homocitrate/citramalate synt... 258 4e-69 PA2011 [E] COG0119 Isopropylmalate/homocitrate/citramalate synth... 240 2e-63 AGl2702 [E] COG0119 Isopropylmalate/homocitrate/citramalate synt... 218 8e-57 SMb21125 [E] COG0119 Isopropylmalate/homocitrate/citramalate syn... 205 5e-53 BMEI1926 [E] COG0119 Isopropylmalate/homocitrate/citramalate syn... 189 2e-48 >RSc0261 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases Rso Ralstonia solanacearum Length = 309 Score = 258 bits (660), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 135/184 (73%), Positives = 150/184 (81%) Query: 2 MSLPKKVKIVEVGPRDGLQNEKETISAEVKIELVNRLSAAGFPNVEAASFVSPKWVPQMA 61 M+ P VK+VEVGPRDGLQNEK +S E K+ELVNRLS AGF NVEAASFVSP+WVPQMA Sbjct: 1 MTFPHFVKVVEVGPRDGLQNEKSPVSTEAKVELVNRLSDAGFVNVEAASFVSPRWVPQMA 60 Query: 62 TSSEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 121 ++VM I R+PG +YSAL PNMKGFEAA A DEVVIF AASEAFSQKNINCSIAES Sbjct: 61 DGADVMARIQRRPGTLYSALTPNMKGFEAAAAALADEVVIFSAASEAFSQKNINCSIAES 120 Query: 122 IERFAEVAKAAKDHRKRLRAAVSCAFGCPYQGEVPLDAVADVVRRFRELGCDEIDIADTI 181 IERF VA+AAKD RLR ++SCA GCPYQGEVP+ +V DVV+R LGCDEIDIADTI Sbjct: 121 IERFVPVARAAKDAGIRLRGSISCALGCPYQGEVPVASVVDVVKRLAALGCDEIDIADTI 180 Query: 182 GVAT 185 GV T Sbjct: 181 GVGT 184 >PA2011 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases Pae Pseudomonas aeruginosa Length = 300 Score = 240 bits (612), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 113/184 (61%), Positives = 140/184 (76%) Query: 2 MSLPKKVKIVEVGPRDGLQNEKETISAEVKIELVNRLSAAGFPNVEAASFVSPKWVPQMA 61 M+LPKKV++VEVGPRDGLQNEK+ I KI LV+ LSAAG +E SFVSPKWVPQMA Sbjct: 1 MNLPKKVRLVEVGPRDGLQNEKQPIEVADKIRLVDDLSAAGLDYIEVGSFVSPKWVPQMA 60 Query: 62 TSSEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 121 S+EV GI ++PGV Y+AL PN+KGFEAALE+GV EV +F AASEAFSQ+NINCSI +S Sbjct: 61 GSAEVFAGIRQRPGVTYAALAPNLKGFEAALESGVKEVAVFAAASEAFSQRNINCSIKDS 120 Query: 122 IERFAEVAKAAKDHRKRLRAAVSCAFGCPYQGEVPLDAVADVVRRFRELGCDEIDIADTI 181 +ERF V +AA+ H+ R+R +SC GCPY G+V VA V R +++GC E+ + DTI Sbjct: 121 LERFVPVLEAARQHQVRVRGYISCVLGCPYDGDVDPRQVAWVARELQQMGCYEVSLGDTI 180 Query: 182 GVAT 185 GV T Sbjct: 181 GVGT 184 >AGl2702 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 321 Score = 218 bits (554), Expect = 8e-57, Method: Compositional matrix adjust. Identities = 108/184 (58%), Positives = 129/184 (70%) Query: 2 MSLPKKVKIVEVGPRDGLQNEKETISAEVKIELVNRLSAAGFPNVEAASFVSPKWVPQMA 61 M P+ VKIVEVG RDGLQNE +S +KIEL+ RL+AAG P VEA +FVSP+ VPQMA Sbjct: 14 MDWPRNVKIVEVGARDGLQNESAEVSTAIKIELIERLAAAGLPAVEAGAFVSPRKVPQMA 73 Query: 62 TSSEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAES 121 S EV G+ R PG Y+ALVPNMKGFEAA+EAGV E+ +F +AS+ FS+ NI CS AES Sbjct: 74 DSREVFQGLKRWPGTAYAALVPNMKGFEAAIEAGVTEIAVFVSASDGFSRHNIGCSRAES 133 Query: 122 IERFAEVAKAAKDHRKRLRAAVSCAFGCPYQGEVPLDAVADVVRRFRELGCDEIDIADTI 181 +ER +VA+AA D R+R VSC GCPY G V D VA + LGC EI + DTI Sbjct: 134 LERLRDVAEAAADRNIRMRGYVSCIAGCPYDGAVAPDDVAAMAEALVALGCYEISLGDTI 193 Query: 182 GVAT 185 GV T Sbjct: 194 GVGT 197 >SMb21125 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases Sme Sinorhizobium meliloti Length = 289 Score = 205 bits (521), Expect = 5e-53, Method: Compositional matrix adjust. Identities = 103/186 (55%), Positives = 127/186 (68%), Gaps = 2/186 (1%) Query: 2 MSLPKK--VKIVEVGPRDGLQNEKETISAEVKIELVNRLSAAGFPNVEAASFVSPKWVPQ 59 M+ P K V IVEV PRDGLQNE ++ E KI LV+ L+ G+ +E SFVSP+WVPQ Sbjct: 1 MTSPAKERVTIVEVAPRDGLQNESRLVATEDKIRLVDLLADCGYERIEVTSFVSPRWVPQ 60 Query: 60 MATSSEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIA 119 +A + VM GI R+PG Y+AL PNM+GFEAAL AG DEV IF +ASE+FS++NINCSIA Sbjct: 61 LADAPAVMAGIVRRPGTRYAALTPNMRGFEAALAAGADEVAIFASASESFSERNINCSIA 120 Query: 120 ESIERFAEVAKAAKDHRKRLRAAVSCAFGCPYQGEVPLDAVADVVRRFRELGCDEIDIAD 179 ESIERF VA+A++ LR VSC CPY+G + A V R +LGC EI + D Sbjct: 121 ESIERFRPVAEASRHRGVPLRGYVSCVVECPYEGAIVPAETARVARLLADLGCYEISLGD 180 Query: 180 TIGVAT 185 TIG T Sbjct: 181 TIGRGT 186 >BMEI1926 [E] COG0119 Isopropylmalate/homocitrate/citramalate synthases Bme Brucella melitensis Length = 287 Score = 189 bits (481), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 99/182 (54%), Positives = 120/182 (65%) Query: 4 LPKKVKIVEVGPRDGLQNEKETISAEVKIELVNRLSAAGFPNVEAASFVSPKWVPQMATS 63 + + V+IVE+ RDGLQNEK + KI L+NRLS G+ +EA SFVSPKWVPQ+A S Sbjct: 1 MAEHVEIVEMAARDGLQNEKRFVPTADKIALINRLSDCGYARIEATSFVSPKWVPQLADS 60 Query: 64 SEVMHGITRKPGVVYSALVPNMKGFEAALEAGVDEVVIFGAASEAFSQKNINCSIAESIE 123 EVM GI R GV YS LVPNMKG+EAA A DE+ +F +ASE FS+ NINC+IAESIE Sbjct: 61 REVMAGIRRADGVRYSVLVPNMKGYEAAAAAHADEIAVFISASEGFSKANINCTIAESIE 120 Query: 124 RFAEVAKAAKDHRKRLRAAVSCAFGCPYQGEVPLDAVADVVRRFRELGCDEIDIADTIGV 183 R + V AA + +R VSC CPY G V AVA V + LGC E+ + DTIG Sbjct: 121 RLSPVIGAAINDGLAIRGYVSCVVECPYDGPVTPQAVASVTEQLFSLGCHEVSLGDTIGR 180 Query: 184 AT 185 T Sbjct: 181 GT 182