BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0038.p (386 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3532 [GEPR] COG0477 Permeases of the major facilitator superfa... 183 6e-46 BMEI0267 [GEPR] COG0477 Permeases of the major facilitator super... 161 2e-39 ECs0925 [GEPR] COG0477 Permeases of the major facilitator superf... 159 9e-39 Z1072 [GEPR] COG0477 Permeases of the major facilitator superfam... 159 1e-38 ybjJ [GEPR] COG0477 Permeases of the major facilitator superfami... 159 1e-38 >PA3532 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 383 Score = 183 bits (464), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 133/349 (38%), Positives = 197/349 (56%), Gaps = 8/349 (2%) Query: 20 KLAIPLFFLLLGVVFATWAARIPAIRDHLQLDAATLALVLLCGGIGAVGSFPLAAWITGH 79 +LA FF + G+V RIPA+++ QLD L LL G+GA+ +FPL+ ++ Sbjct: 10 RLACIYFFAMAGLVIGNLMGRIPALKEQTQLDERALGQALLGVGVGALTAFPLSGFLVQR 69 Query: 80 YGARHSTLYAGLALLVSLPLLGLAPNVASLMLICTLYGAASSCFDVAINALGAQAERDAG 139 G+R + L +L+ PLLGL+ L L + G + + DVA+N ER G Sbjct: 70 IGSRSVVIGGCLIMLLVFPLLGLSQGWWQLALAFYVLGVSFAGMDVAMNIQAVDVERLLG 129 Query: 140 RPIMSMLHGWFCVGTFSGALAASAVAGMGIAPIWHFLLVAALFLYPLYACYEALPDDRPE 199 +P MSMLHG + +G GAL+A+A+AG+ P WHFL++ AL L L AL P Sbjct: 130 KPCMSMLHGMYSLGCLVGALSAAALAGL--TPFWHFLILTALGLLSLPFFVRALLPPDPS 187 Query: 200 HDPARK--LFVLPHGHLVVLGVIAFCGAIVEGSVADWSGIYMKDHIGASDGATPLAYAAF 257 ARK F LP L+ LG++ C + EG VADWS +++ + AS+ L +AAF Sbjct: 188 KAGARKGGGFTLPPRALLGLGLLILCAFVSEGGVADWSALFLHSVLDASERVAALGFAAF 247 Query: 258 AGMMLIMRMIGDRLKARYDARRVVWVGTLIASLGIALAVAAPGMTLAILGFAIAGTGVAA 317 + M++ R+ GDRL+ R D ++ +A+LG+ +A+ +P L+I GF + G G++ Sbjct: 248 SAAMVVGRLFGDRLRGRIDDAPLLRGLGSLATLGMLVALFSPWPALSIAGFGVVGLGLSV 307 Query: 318 VFPFVFSAAGRHGS----SALAAVATLGYSGSLIGPPVFGFLAHGWGLQ 362 + P V SAAG +AAV+T+GY G L+GPP+ G LAH GL+ Sbjct: 308 MVPIVISAAGNQPGIDPVIGVAAVSTVGYGGLLMGPPLIGLLAHEIGLR 356 >BMEI0267 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 397 Score = 161 bits (407), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 114/354 (32%), Positives = 183/354 (51%), Gaps = 16/354 (4%) Query: 19 RKLAIPLFFLLLGVVFATWAARIPAIRDHLQLDAATLALVLLCGGIGAVGSFPLAAWITG 78 ++A+ L FL+ G +F WA +IP + L LD+A + L++L G+G++ P+A ++ Sbjct: 21 ERIAVALLFLMNGYIFGGWAPKIPEFAERLGLDSAGMGLMILVCGLGSLAMMPVAGALSA 80 Query: 79 HYGARHSTLYAGLALLVSLPLLGLAPNVASLMLICTLYGAASSCFDVAINALGAQAERDA 138 H G+ LA + +L ++ L PNV + +++ +G + DV++NA E+ Sbjct: 81 HRGSGIVVRIFALAFIPALLIITLVPNVVTAVIVMLYFGGTMAAMDVSMNANAVAVEKKM 140 Query: 139 GRPIMSMLHGWFCVGTFSGALAASAVAGMGIAP---IWHFL--LVAALFLYPLYACYEAL 193 R IMS H ++ +G GA A G IA I H L ++AA L + A + Sbjct: 141 RRAIMSSCHAFWSLGGLIGA----ATGGFLIAQFGSIVHALVTMIAATILI-IVAWPSII 195 Query: 194 PDDRPEH-DPARKLFVLPHGHLV-VLGVIAFCGAIVEGSVADWSGIYMKDHIGASDGATP 251 PD H D ++ LP L ++GV+A + EG++ DW +M+ +GAS Sbjct: 196 PDTEHHHPDGEKQKLALPRNPLPWLVGVMALFSMVPEGAILDWGAYHMRQDLGASVTVAG 255 Query: 252 LAYAAFAGMMLIMRMIGDRLKARYDARRVVWVGTLIASLGIALAVAAPGMTLAILGFAIA 311 +AAF+G M +MR GD ++ R+ A + + T IA +G+ + AI+GFAI Sbjct: 256 FGFAAFSGSMAVMRFAGDLVRDRFGAVKTLRACTAIAIIGMLIVGFGNSSATAIIGFAIC 315 Query: 312 GTGVAAVFPFVFSAAGR----HGSSALAAVATLGYSGSLIGPPVFGFLAHGWGL 361 G G++ + P FS AG + S L+ TLGYSG L+ P + GF+A G Sbjct: 316 GIGISNMVPIAFSMAGNMPGVNPSVGLSIATTLGYSGMLVAPSLIGFVARHSGF 369 >ECs0925 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 402 Score = 159 bits (402), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 120/368 (32%), Positives = 181/368 (49%), Gaps = 14/368 (3%) Query: 11 SSPLRLIWRKLAIPLFFLLLGVVFATWAARIPAIRDHLQLDAATLALVLLCGGIGAVGSF 70 SS L R A+ +FF L G++ A+WA R PAIRD L + A + VL IG++ Sbjct: 5 SSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGI 64 Query: 71 PLAAWITGHYGARHSTLYAGLALLVSLPLLGLAPNVASLMLICT---LYGAASSCFDVAI 127 +AW+ +G R+ L LV + +L LA + S +L ++GA+ +VAI Sbjct: 65 LCSAWLVKRFGTRNVILVTMSCALVGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAI 124 Query: 128 NALGAQAERDAGRPIMSMLHGWFCVGTFSGALAASAVAGMGIAPIWHFLLVAALFLYPLY 187 N GA ER+ + ++ M+HG++ +GT +GA A+ G+ H LL A + + P+Y Sbjct: 125 NVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIY 184 Query: 188 ACYEALPD-------DRPEHDPARKLFVLPHGHLVVLGVIAFCGAIVEGSVADWSGIYMK 240 +A+PD D +H F L+++GV+ A EGS DW + M Sbjct: 185 IAIQAIPDGTGKNAADGTQHGEKGVPFYRDI-QLLLIGVVVLAMAFAEGSANDWLPLLMV 243 Query: 241 DHIGASDGATPLAYAAFAGMMLIMRMIGDRLKARYDARRVVWVGTLIASLGIALAVAAPG 300 D G S + L YA F M + R G RY VV L+ +LGI L + Sbjct: 244 DGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFIDRYSRVAVVRASALMGALGIGLIIFVDS 303 Query: 301 MTLAILGFAIAGTGVAAVFPFVFSAAGRHGSSA---LAAVATLGYSGSLIGPPVFGFLAH 357 +A + + G G + FP SAA G A ++ VAT GY L+GPP+ G+L Sbjct: 304 AWVAGVSVVLWGLGASLGFPLTISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYLGE 363 Query: 358 GWGLQAAL 365 +GL++A+ Sbjct: 364 HYGLRSAM 371 >Z1072 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 402 Score = 159 bits (402), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 120/368 (32%), Positives = 181/368 (49%), Gaps = 14/368 (3%) Query: 11 SSPLRLIWRKLAIPLFFLLLGVVFATWAARIPAIRDHLQLDAATLALVLLCGGIGAVGSF 70 SS L R A+ +FF L G++ A+WA R PAIRD L + A + VL IG++ Sbjct: 5 SSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGI 64 Query: 71 PLAAWITGHYGARHSTLYAGLALLVSLPLLGLAPNVASLMLICT---LYGAASSCFDVAI 127 +AW+ +G R+ L LV + +L LA + S +L ++GA+ +VAI Sbjct: 65 LCSAWLVKRFGTRNVILVTMSCALVGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAI 124 Query: 128 NALGAQAERDAGRPIMSMLHGWFCVGTFSGALAASAVAGMGIAPIWHFLLVAALFLYPLY 187 N GA ER+ + ++ M+HG++ +GT +GA A+ G+ H LL A + + P+Y Sbjct: 125 NVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIY 184 Query: 188 ACYEALPD-------DRPEHDPARKLFVLPHGHLVVLGVIAFCGAIVEGSVADWSGIYMK 240 +A+PD D +H F L+++GV+ A EGS DW + M Sbjct: 185 IAIQAIPDGTGKNAADGTQHGEKGVPFYRDI-QLLLIGVVVLAMAFAEGSANDWLPLLMV 243 Query: 241 DHIGASDGATPLAYAAFAGMMLIMRMIGDRLKARYDARRVVWVGTLIASLGIALAVAAPG 300 D G S + L YA F M + R G RY VV L+ +LGI L + Sbjct: 244 DGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFIDRYSRVAVVRAXALMGALGIGLIIFVDS 303 Query: 301 MTLAILGFAIAGTGVAAVFPFVFSAAGRHGSSA---LAAVATLGYSGSLIGPPVFGFLAH 357 +A + + G G + FP SAA G A ++ VAT GY L+GPP+ G+L Sbjct: 304 AWVAGVSVVLWGLGASLGFPLTISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYLGE 363 Query: 358 GWGLQAAL 365 +GL++A+ Sbjct: 364 HYGLRSAM 371 >ybjJ [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 402 Score = 159 bits (401), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 119/368 (32%), Positives = 181/368 (49%), Gaps = 14/368 (3%) Query: 11 SSPLRLIWRKLAIPLFFLLLGVVFATWAARIPAIRDHLQLDAATLALVLLCGGIGAVGSF 70 SS L R A+ +FF L G++ A+WA R PAIRD L + A + VL IG++ Sbjct: 5 SSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGI 64 Query: 71 PLAAWITGHYGARHSTLYAGLALLVSLPLLGLAPNVASLMLICT---LYGAASSCFDVAI 127 +AW+ +G R+ L L+ + +L LA + S +L ++GA+ +VAI Sbjct: 65 LCSAWLVKRFGTRNVILVTMSCALIGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAI 124 Query: 128 NALGAQAERDAGRPIMSMLHGWFCVGTFSGALAASAVAGMGIAPIWHFLLVAALFLYPLY 187 N GA ER+ + ++ M+HG++ +GT +GA A+ G+ H LL A + + P+Y Sbjct: 125 NVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMALTAFGVPATVHILLAALVGIAPIY 184 Query: 188 ACYEALPD-------DRPEHDPARKLFVLPHGHLVVLGVIAFCGAIVEGSVADWSGIYMK 240 +A+PD D +H F L+++GV+ A EGS DW + M Sbjct: 185 IAIQAIPDGTGKNAADGTQHGEKGVPFYRDI-QLLLIGVVVLAMAFAEGSANDWLPLLMV 243 Query: 241 DHIGASDGATPLAYAAFAGMMLIMRMIGDRLKARYDARRVVWVGTLIASLGIALAVAAPG 300 D G S + L YA F M + R G RY VV L+ +LGI L + Sbjct: 244 DGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFIDRYSRVAVVRASALMGALGIGLIIFVDS 303 Query: 301 MTLAILGFAIAGTGVAAVFPFVFSAAGRHGSSA---LAAVATLGYSGSLIGPPVFGFLAH 357 +A + + G G + FP SAA G A ++ VAT GY L+GPP+ G+L Sbjct: 304 AWVAGVSVVLWGLGASLGFPLTISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYLGE 363 Query: 358 GWGLQAAL 365 +GL++A+ Sbjct: 364 HYGLRSAM 371